JPH0576310B2 - - Google Patents

Info

Publication number
JPH0576310B2
JPH0576310B2 JP60220494A JP22049485A JPH0576310B2 JP H0576310 B2 JPH0576310 B2 JP H0576310B2 JP 60220494 A JP60220494 A JP 60220494A JP 22049485 A JP22049485 A JP 22049485A JP H0576310 B2 JPH0576310 B2 JP H0576310B2
Authority
JP
Japan
Prior art keywords
hemostatic material
material according
density
fabric
tricot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60220494A
Other languages
English (en)
Other versions
JPS6190668A (ja
Inventor
Hariideru Buroodonatsu Seshiru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Hospital Services Inc
Original Assignee
Johnson and Johnson Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Products Inc filed Critical Johnson and Johnson Products Inc
Publication of JPS6190668A publication Critical patent/JPS6190668A/ja
Publication of JPH0576310B2 publication Critical patent/JPH0576310B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/20—Tampons, e.g. catamenial tampons; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01034—Non-adhesive bandages or dressings characterised by a property
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04B—KNITTING
    • D04B21/00—Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84—Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405—Additives, e.g. for odour, disinfectant or pH control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00106—Wound bandages emergency bandages, e.g. for first aid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00238—Wound bandages characterised by way of knitting or weaving
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Textile Engineering (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Knitting Of Fabric (AREA)

Description

【発明の詳細な説明】
本発明は出血を止めるための手術用止血材に関
し、さらに具体的にに、優れた取扱い特性及び止
血特性を有する酸化セルロース製の編み地に関す
る。 出血を止めることは、ある種の手術及び種々の
突発的創傷において重要な問題である。例えば、
腎臓、脳もしくは肝臓からの出血、又は切断した
毛細血管及び静脈からの永続的な出血は、縫合又
は結さつのような通常の方法によつて止血するこ
とが特に困難であり、また多くの場合、生命を危
険にさらすほど重大である。塩化第二鉄、トロン
ピン等の止血剤をしみ込ませた通常のガーゼパツ
ド又はこれらに類したものが出血を止めるために
長年使用されてきた。しかしながら、この種の止
血材は、異物組織反応が生じるので、閉じた創傷
中に残しておくことができない。 出血を止めるために、必要ならば、創傷部位中
に残しておくことが可能であり、悪影響を与える
組織反応なしに生体によつてついには吸収される
吸収性の止血材が開発された。そのような吸収材
としては、ラクチド及びグリコリドの重合体又は
それらの共重合体並びに酸化セルロースがある。
吸収性止血材としての酸化セルロースの製造法及
び使用法が米国特許第3364200号に開示されてい
る。 簡単に説明すると、米国特許第3364200号は、
プライトレーヨン再生セルロースをフレオン溶媒
中の四酸化二窒素のような酸化剤で処理すること
による酸化セルロースの製造法を開示している。
酸化後、布は四塩化炭素のような溶媒、次いで50
％イソプロピルアルコール水溶液、次に99％イソ
プロピルアルコールで十分洗浄される。酸化の前
に、この止血材はガーゼ、ニツト、織布、フエル
ト又はステーブルフアイバーの集積塊のような所
望の形態に構成される。米国特許第3364200号の
実施例１は、1.6デニールの連続フイラメントブ
ライトレーヨンからの止血性手術用ガーゼの製造
法に記載している。このレーヨンはまず90本のフ
イラメントからなる合計150デニールの糸にされ、
その後、ワイルドマン（wildman）２８交差、
ヒゲ針編機で13平方インチ（約10.9m2）当たり約
１ポンド（約453.6ｇ）の重量並びに直線インチ
当たり18コース及び18ウエールを有する平らなジ
ヤージー組織に編成される。 米国特許第3364200号、特にその実施例１の教
示によつて編成したジヤージー布地は創傷部位の
表面形状にうまく適合する軽量の目の荒いメツシ
ユ材であり、出血を止めるのに効果的である。本
発明は、改良された止血材に関し、同様に酸化セ
ルロースで編成されている。これは米国特許第
3364200号の止血材より出血を止めるのに効果的
であり、かつ他の改良された特性も有する。 本発明の吸収性止血材は、その後に公知の技術
によつて酸化されるプライトレーヨンで編成され
た縦編みトリコツト布である。この布は、単一プ
ライの厚さが少なくとも0.5mm、少なくとも0.03
ｇ／cm2の密度、150cm3／sec／cm2未満の空〓率及び
生地の乾燥重量の３倍の液体吸収力を有すること
によつて特徴づけられる。 本発明の編成布は過度の重量を持つことなしに
良好な崇を有し、柔軟で、かつドレープ性を有し
ているので、適用される表面の形状に十分に適合
する。この布は切り口に沿う伝染又はほつれなし
に適当な寸法に切断することができる。酸化後の
生地強度は手術用止血材として使用するのに十分
適合する。 本発明の布の止血特性は、先行技術の編成生地
の止血特性より優れている。さらに、本発明の布
の増加した嵩は、先行技術の布地では折り重ねる
ことを必要としたのに反し、本発明の布を単一プ
ライで使用することを可能にする。 酸化セルロースから成る本発明の改良された止
血性布は上述した通り、厚さ、嵩、空〓率及び液
体吸収力というそれらの物理的特性によつて最良
に特徴づけられている。これらの特性を有する適
切な布は32ゲージ編機で編成品位１２に60デニー
ル、18フイラメントブライトレーヨン糸を編成す
ることによつて構成される。適切なトリコツト生
地組織はフロントバー１−０、10−11、バツクバ
ー２−３、１−０である。フロントバーに与えら
れた長い振り移動の結果がバツクガイドバーのた
めの70インチ（約178cm）ランナーに反して188イ
ンチ（約477cm）ランナーになり、布の嵩及びを
密度を増大する。この特別な組織におけるフロン
トバーランナーのバツクバーランナーに対する比
は１：2.68である。 以上に説明したようにして製造した布の物理的
特性及び止血性を米国特許第3364200号の実施例
１に記載した先行技術の布の特性と比較した。そ
の結果を次に示す。
【表】 本発明のトリコツト布は合計約40〜80デニール
のプライトレーヨン系から編成することができ
る。各糸は10〜25本の別個のフイラメントから成
るが、それぞれのフイラメントは吸収時間が長く
なるのを避けるために５デニール未満であるのが
好ましい。 本発明の大きい嵩及び高い布密度は、28ゲージ
又はより密、好ましくは32ゲージで、ほぼ10又は
12の生地品位（１インチ当たり40〜48コース）に
編成することによつて達成される。少なくとも６
ニードルスペース、好ましくは８〜12ニードルス
ペースの長いガイドバー振り移動が布の厚さ及び
密度をさらに大きくする。 同等の物理的特性を生じる他の縦編みトリコツ
ト布組織が本発明の改良された止血材の製造に利
用できるのは勿論のことであり、そのような組織
は当業者に明白である。

Claims (1)

  1. 【特許請求の範囲】 １ 少なくとも0.03ｇ／cm2の密度と150cm3／sec／
    cm2未満の空〓率、および自身の乾燥重量の少なく
    とも３倍の液体吸収力を有する酸化セルロース縦
    編みトリコツト布を含む手術用止血材。 ２ 前記トリコツト布は、10〜25本のフイラメン
    トを含む約40〜80デニールのブライトレーヨン糸
    から得られる特許請求の範囲第１項記載の止血
    材。 ３ 前記ブライトレーヨン糸は、18本のフイラメ
    ントを含み、かつ60デニールである特許請求の範
    囲第２項記載の止血材。 ４ 前記トリコツト布は約0.05ｇ／cm2の密度と約
    60cm3／sec／cm2未満の空〓率、および自身の乾燥
    重量の約3.8倍の液体吸収力を有する特許請求の
    範囲第３項記載の止血材。 ５ 前記トリコツト布は40〜80デニールの酸化セ
    ルロール糸を含む特許請求の範囲第１項記載の止
    血材。 ６ 前記縦編みトリコツト布の編み組織は、 フロントバー……１−０、10−11、 バツクバー……２−３、１−０、および バツクバーランナーのフロントバーランナーに
    対する比が約2.7 である特許請求の範囲第５項記載の止血材。 ７ 前記フロントバーランナーが約190インチ
    （約483cm）、また前記バツクバーランナーが約70
    インチ（約178cm）である特許請求の範囲第６項
    記載の止血材。 ８ 前記止血材が約0.05ｇ／cm2の密度と約60cm3／
    sec／cm2未満の空〓率、および自身の乾燥重量の
    約3.8倍の液体吸収力を有する特許請求の範囲第
    ６項記載の止血材。 ９ 前記トリコツト布は32ゲージで、12インチ品
    位を有する特許請求の範囲第６項記載の止血材。 １０ 前記トリコツト布は32ゲージで、12インチ
    品位を有し、かつその編み組織は、 フロントバー……１−０、10−11、および バツクバー……２−３、１−０で、さらに60デ
    ニールの糸で構成される特許請求の範囲第１項記
    載の止血材。
JP60220494A 1984-10-05 1985-10-04 酸化セルロースからなる手術用止血材 Granted JPS6190668A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US657997 1984-10-05
US06/657,997 US4626253A (en) 1984-10-05 1984-10-05 Surgical hemostat comprising oxidized cellulose

Publications (2)

Publication Number Publication Date
JPS6190668A JPS6190668A (ja) 1986-05-08
JPH0576310B2 true JPH0576310B2 (ja) 1993-10-22

Family

ID=24639487

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60220494A Granted JPS6190668A (ja) 1984-10-05 1985-10-04 酸化セルロースからなる手術用止血材

Country Status (12)

Country Link
US (1) US4626253A (ja)
EP (1) EP0177064B1 (ja)
JP (1) JPS6190668A (ja)
AT (1) ATE66155T1 (ja)
AU (1) AU580337B2 (ja)
CA (1) CA1253321A (ja)
DE (1) DE3583786D1 (ja)
HK (1) HK17392A (ja)
IE (1) IE57311B1 (ja)
NZ (1) NZ213571A (ja)
SG (1) SG107791G (ja)
ZA (1) ZA857682B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013213213A (ja) * 2011-09-12 2013-10-17 Gunze Ltd 親水性化セルロース繊維

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