JPH0586220B2 - - Google Patents

Info

Publication number: JPH0586220B2
Authority: JP; Japan
Prior art keywords: abrasive material; vibrator; present; vibration; stratum corneum
Prior art date: 1986-03-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP4417286A

Other languages

English (en)

Japanese (ja)

Other versions

JPS62270144A (ja

Inventor

Keiji Fukui

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Advance KK

Original Assignee

Advance KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-03

Filing date

1986-03-03

Publication date

1993-12-10

1986-03-03 Application filed by Advance KK filed Critical Advance KK

1986-03-03 Priority to JP4417286A priority Critical patent/JPS62270144A/ja

1987-11-24 Publication of JPS62270144A publication Critical patent/JPS62270144A/ja

1993-12-10 Publication of JPH0586220B2 publication Critical patent/JPH0586220B2/ja

Status Granted legal-status Critical Current

Links

239000003082 abrasive agent Substances 0.000 claims description 28
230000037380 skin damage Effects 0.000 claims description 3
210000000434 stratum corneum Anatomy 0.000 description 12
210000003491 skin Anatomy 0.000 description 8
230000006378 damage Effects 0.000 description 7
229940079593 drug Drugs 0.000 description 7
239000003814 drug Substances 0.000 description 7
230000005540 biological transmission Effects 0.000 description 6
239000010419 fine particle Substances 0.000 description 6
239000000463 material Substances 0.000 description 6
239000002245 particle Substances 0.000 description 6
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
230000007794 irritation Effects 0.000 description 4
239000000758 substrate Substances 0.000 description 4
102000011782 Keratins Human genes 0.000 description 3
108010076876 Keratins Proteins 0.000 description 3
238000000034 method Methods 0.000 description 3
238000005498 polishing Methods 0.000 description 3
229910001220 stainless steel Inorganic materials 0.000 description 3
239000010935 stainless steel Substances 0.000 description 3
210000001519 tissue Anatomy 0.000 description 3
102000004877 Insulin Human genes 0.000 description 2
108090001061 Insulin Proteins 0.000 description 2
UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
230000001154 acute effect Effects 0.000 description 2
239000000853 adhesive Substances 0.000 description 2
230000001070 adhesive effect Effects 0.000 description 2
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 2
229910052593 corundum Inorganic materials 0.000 description 2
239000010431 corundum Substances 0.000 description 2
238000010586 diagram Methods 0.000 description 2
239000010432 diamond Substances 0.000 description 2
230000000694 effects Effects 0.000 description 2
229940125396 insulin Drugs 0.000 description 2
229910052742 iron Inorganic materials 0.000 description 2
239000011148 porous material Substances 0.000 description 2
108090000765 processed proteins & peptides Proteins 0.000 description 2
VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
239000004925 Acrylic resin Substances 0.000 description 1
229920000178 Acrylic resin Polymers 0.000 description 1
229910052580 B4C Inorganic materials 0.000 description 1
208000035473 Communicable disease Diseases 0.000 description 1
208000018522 Gastrointestinal disease Diseases 0.000 description 1
WGLPBDUCMAPZCE-UHFFFAOYSA-N Trioxochromium Chemical compound O=[Cr](=O)=O WGLPBDUCMAPZCE-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
230000004913 activation Effects 0.000 description 1
239000012790 adhesive layer Substances 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
INAHAJYZKVIDIZ-UHFFFAOYSA-N boron carbide Chemical compound B12B3B4C32B41 INAHAJYZKVIDIZ-UHFFFAOYSA-N 0.000 description 1
239000000919 ceramic Substances 0.000 description 1
229910000423 chromium oxide Inorganic materials 0.000 description 1
239000004927 clay Substances 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
229910003460 diamond Inorganic materials 0.000 description 1
238000009792 diffusion process Methods 0.000 description 1
238000001647 drug administration Methods 0.000 description 1
229910001651 emery Inorganic materials 0.000 description 1
239000002223 garnet Substances 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
239000004579 marble Substances 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
229930014626 natural product Natural products 0.000 description 1
238000000554 physical therapy Methods 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
-1 prints Substances 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
238000004080 punching Methods 0.000 description 1
230000029058 respiratory gaseous exchange Effects 0.000 description 1
HBMJWWWQQXIZIP-UHFFFAOYSA-N silicon carbide Chemical compound [Si+]#[C-] HBMJWWWQQXIZIP-UHFFFAOYSA-N 0.000 description 1
229910010271 silicon carbide Inorganic materials 0.000 description 1
238000005507 spraying Methods 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1

Landscapes

Surgical Instruments (AREA)

JP4417286A 1986-03-03 1986-03-03 経皮投薬用皮膚損傷装置 Granted JPS62270144A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP4417286A JPS62270144A (ja)	1986-03-03	1986-03-03	経皮投薬用皮膚損傷装置

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP4417286A JPS62270144A (ja)	1986-03-03	1986-03-03	経皮投薬用皮膚損傷装置

Publications (2)

Publication Number	Publication Date
JPS62270144A JPS62270144A (ja)	1987-11-24
JPH0586220B2 true JPH0586220B2 (de)	1993-12-10

Family

ID=12684163

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP4417286A Granted JPS62270144A (ja)	1986-03-03	1986-03-03	経皮投薬用皮膚損傷装置

Country Status (1)

Country	Link
JP (1)	JPS62270144A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2703035B2 (ja) *	1989-02-28	1998-01-26	久光製薬株式会社	イオントフォレーゼ用デバイス
US6835184B1 (en) *	1999-09-24	2004-12-28	Becton, Dickinson And Company	Method and device for abrading skin
PT2152358E (pt) *	2007-04-27	2011-06-07	Echo Therapeutics Inc	Dispositivo de permeação da pele para detecção de analito ou distribuição transdérmica de droga
WO2012078649A1 (en) *	2010-12-06	2012-06-14	Follica, Inc.	Methods for treating baldness and promoting hair growth

1986
- 1986-03-03 JP JP4417286A patent/JPS62270144A/ja active Granted

Also Published As

Publication number	Publication date
JPS62270144A (ja)	1987-11-24

Legal Events

Date	Code	Title	Description
2006-03-03	EXPY	Cancellation because of completion of term

Publication	Publication Date	Title
CN101711130B (zh)	2013-03-27	形成多个微导管的装置
JPH0363913B2 (de)	1991-10-03
US7316665B2 (en)	2008-01-08	Method and device for the delivery of a substance including a covering
CA2315469C (en)	2009-04-21	Method and apparatus for the transdermal administration of a substance
EP2121111B1 (de)	2018-03-14	Applikator für mikronadelanordnung
CN1905920A (zh)	2007-01-31	用于透皮递送的系统和方法
WO1998017184A1 (en)	1998-04-30	Apparatus and method for sonically enhanced drug delivery
NO972897D0 (no)	1997-06-20	Partikkel-utleveringsanordning
JP2010515469A (ja)	2010-05-13	皮膚表面の研磨処理装置
US10525246B2 (en)	2020-01-07	Microdevice and method for transdermal delivery and sampling of active substances
WO2003039622A3 (en)	2003-08-14	Novel iontophoretic drug delivery systems
WO1998017184A9 (en)	1998-08-06	Apparatus and method for sonically enhanced drug delivery
JP2007503268A (ja)	2007-02-22	免疫応答修飾化合物の送達
JP4647863B2 (ja)	2011-03-09	薬剤投与具及び薬剤投与装置
CA2545798A1 (en)	2004-09-02	Ultrasonically enhanced saline treatment for burn damaged skin
AU2005228177A1 (en)	2005-10-13	Microsurgical tissue treatment system
WO2007116959A1 (ja)	2007-10-18	マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置
CA2316534A1 (en)	2001-03-24	Method and device for abrading skin
JP4145628B2 (ja)	2008-09-03	美容処理装置
JPS62270144A (ja)	1987-11-24	経皮投薬用皮膚損傷装置
JP2002535293A (ja)	2002-10-22	無針の経皮的粉末薬物送達を増強する方法
JPH02224752A (ja)	1990-09-06	イオントフォレーゼ用デバイス
JPH0794380B2 (ja)	1995-10-11	経皮投薬用皮膚処理剤
EP1199084A3 (de)	2004-03-17	Iontophoretisches Gerät mit hoher Stromdichte
JP2008512199A (ja)	2008-04-24	皮膚への接着及び伸展性（ｃｏｍｐｌｉａｎｃｅ）が改善された微小突起アレイ