JPH07188230A - １−（２−フルオロシクロプロピル）−キノロンカルボン酸および１−（２−フルオロシクロプロピル）−ナフチリドンカルボン酸誘導体 - Google Patents

１−（２−フルオロシクロプロピル）−キノロンカルボン酸および１−（２−フルオロシクロプロピル）−ナフチリドンカルボン酸誘導体

Info

Publication number
JPH07188230A
JPH07188230A JP6301672A JP30167294A JPH07188230A JP H07188230 A JPH07188230 A JP H07188230A JP 6301672 A JP6301672 A JP 6301672A JP 30167294 A JP30167294 A JP 30167294A JP H07188230 A JPH07188230 A JP H07188230A
Authority
JP
Japan
Prior art keywords
oxo
acid
dihydro
fluoro
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6301672A
Other languages
English (en)
Japanese (ja)
Inventor
Uwe Petersen
ウベ・ペーターゼン
Thomas Schenke
トーマス・シエンケ
Stephan Boehm
シユテフアン・ベーム
Rolf Grosser
ロルフ・グロサー
Klaus Dieter Dr Bremm
クラウス・デイーター・ブレム
Rainer Endermann
ライナー・エンデルマン
Karl Georg Metzger
カール・ゲオルク・メツツガー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPH07188230A publication Critical patent/JPH07188230A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP6301672A 1993-11-16 1994-11-11 １−（２−フルオロシクロプロピル）−キノロンカルボン酸および１−（２−フルオロシクロプロピル）−ナフチリドンカルボン酸誘導体 Pending JPH07188230A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4339134.6 1993-11-16
DE4339134A DE4339134A1 (de) 1993-11-16 1993-11-16 1-(2-Fluorcyclopropyl)-chinolon- und -naphthyridoncarbonsäure-Derivate

Publications (1)

Publication Number Publication Date
JPH07188230A true JPH07188230A (ja) 1995-07-25

Family

ID=6502741

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6301672A Pending JPH07188230A (ja) 1993-11-16 1994-11-11 １−（２−フルオロシクロプロピル）−キノロンカルボン酸および１−（２−フルオロシクロプロピル）−ナフチリドンカルボン酸誘導体

Country Status (27)

Country Link
US (1) US5545642A (2)
EP (1) EP0653425A1 (2)
JP (1) JPH07188230A (2)
KR (1) KR950014114A (2)
CN (1) CN1106412A (2)
AU (2) AU681703B2 (2)
BG (1) BG62003B1 (2)
CA (1) CA2135548A1 (2)
CO (1) CO4180605A1 (2)
CZ (1) CZ280594A3 (2)
DE (1) DE4339134A1 (2)
EE (1) EE9400240A (2)
FI (1) FI945360A7 (2)
HR (1) HRP940833A2 (2)
HU (1) HUT70175A (2)
IL (1) IL111624A0 (2)
LV (1) LV11328B (2)
NO (1) NO302367B1 (2)
NZ (1) NZ264905A (2)
PE (1) PE32395A1 (2)
PL (1) PL305862A1 (2)
RU (1) RU94040885A (2)
SK (1) SK137194A3 (2)
SV (1) SV1994000064A (2)
TW (1) TW273547B (2)
YU (1) YU65494A (2)
ZA (1) ZA949052B (2)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058928A1 (fr) * 1997-06-23 1998-12-30 Yoshitomi Pharmaceutical Industries, Ltd. Agent prophylactique ou therapeutique contre des maladies attribuables a une infection par des helicobacters

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100236852B1 (ko) * 1992-10-09 2000-03-02 나가야마 오사무 플루오로 퀴놀린 유도체
EP0870500B1 (en) * 1995-12-22 2008-02-20 Nagase ChemteX Corporation Anti-helicobacter pylori agent
DE10108750A1 (de) * 2001-02-23 2002-09-05 Bayer Ag Verbessertes Verfahren zur Herstellung von Fluorchinoloncarbonsäuren
WO2004108680A1 (ja) * 2003-06-06 2004-12-16 Daiichi Pharmaceutical Co., Ltd. 光学活性なキノロンカルボン酸誘導体の製造中間体およびその製造法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274167A (en) * 1989-01-26 1993-12-28 Bayer Aktiengesellschaft Polymeriable optically active (meth) acrylic acid derivatives
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
KR910009333B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
KR910009331B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 디아자비시클로아민 화합물과 그의 제조방법
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
EP0593766B1 (en) * 1991-05-28 2000-09-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058928A1 (fr) * 1997-06-23 1998-12-30 Yoshitomi Pharmaceutical Industries, Ltd. Agent prophylactique ou therapeutique contre des maladies attribuables a une infection par des helicobacters
US6221864B1 (en) 1997-06-23 2001-04-24 Welfide Corporation Prophylactic or therapeutic agent for diseases attributable to infection with helicobacters

Also Published As

Publication number Publication date
KR950014114A (ko) 1995-06-15
DE4339134A1 (de) 1995-05-18
AU681703B2 (en) 1997-09-04
BG62003B1 (bg) 1998-12-30
FI945360A0 (fi) 1994-11-14
US5545642A (en) 1996-08-13
HU9403288D0 (en) 1995-01-30
EE9400240A (et) 1996-02-15
AU7773094A (en) 1995-05-25
LV11328B (en) 1996-12-20
NO944365D0 (no) 1994-11-15
PL305862A1 (en) 1995-05-29
FI945360L (fi) 1995-05-17
ZA949052B (en) 1995-07-19
SV1994000064A (es) 1995-05-25
HRP940833A2 (en) 1996-12-31
NO302367B1 (no) 1998-02-23
RU94040885A (ru) 1996-11-20
CN1106412A (zh) 1995-08-09
CZ280594A3 (en) 1995-08-16
EP0653425A1 (de) 1995-05-17
HUT70175A (en) 1995-09-28
NZ264905A (en) 1995-11-27
CO4180605A1 (es) 1995-06-07
TW273547B (2) 1996-04-01
PE32395A1 (es) 1995-12-15
SK137194A3 (en) 1995-06-07
IL111624A0 (en) 1995-01-24
LV11328A (lv) 1996-06-20
FI945360A7 (fi) 1995-05-17
BG99179A (en) 1995-07-28
CA2135548A1 (en) 1995-05-17
YU65494A (sh) 1997-09-30
AU2559997A (en) 1997-09-04
NO944365L (no) 1995-05-18

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