JPH07304641A - Tooth paste composition and its production - Google Patents

Abstract

PURPOSE:To produce a tooth paste composition low in viscosity change with time, free from liquid separation and excellent in shape retention by blending a polyoxyethylene-hardened castol oil with a specified ratio of a polyhydric alcohol/water. CONSTITUTION:This tooth paste composition is produced by blending (A) a polyoxyethylene-hardened castor oil having 40 to 80 number of moles of additional ethylene oxide with (B) a polyhydric alcohol/water-based solution having a ratio of 1:1.4 to 1:2.2 and subsequently blending (C) pyrogenous silica therewith. specific surface area measured by BET method and the mixture ratio of the components (A), (B) and (C) is preferably (A): 0.1 to 2wt.%, (B): 25 to 40wt.% and (C): 1 to 4wt.%.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dentifrice composition and a method for producing the same, and more particularly to a dentifrice composition which exhibits little change in viscosity over time and has good shape retention, and a method for producing the same.

[0002]

2. Description of the Related Art Calcium carbonate, calcium phosphate, aluminum hydroxide, silica, etc. are widely used as abrasives used in dentifrice compositions, but recently, they have a transparent formulation and a light weight. There is an increasing demand for silica-based abrasives that provide a feeling of use. Among them, the igneous silica has a feature that it has a high water absorption and a good shape retention property, and the ignitable silica is used for improving the feeling of use of the dentifrice composition. As a technique of a dentifrice composition having good shape retention by blending a pyrogenic silica, it is disclosed in JP-A-60-75412, and an oral composition containing a blend of a pyrogenic silica and polyethylene glycol. The product is disclosed in JP-A-63-162617. However, in our study, it has been found that these techniques have a problem that the use of the fumed silica causes a rapid change in the viscosity with the passage of time immediately after the production. For this reason, if the viscosity is too low immediately after production, or becomes too high over time, it becomes difficult to squeeze out of the tube, and solid-liquid separation tends to occur, which causes inconveniences and quality control can be performed. It gets harder. From the above, it is considered that there is room for improvement in the viscosity change with time when the ignitable silica is blended in the dentifrice composition.

[0003]

Means for Solving the Problems The inventors of the present invention have conducted diligent research on the improvement of the daily viscosity change of a dentifrice composition containing ignitable silica. As a result, polyoxyethylene hydrogenated castor oil and a specific ratio of It has been found that by adding a polyhydric alcohol / water, it is possible to obtain a stable dentifrice composition with little viscosity change over time and without liquid separation. Further, knowledge has been obtained regarding the manufacturing method thereof, and the present invention has been completed.

The present invention provides a dentifrice composition, which is characterized by comprising a polyoxyethylene hydrogenated castor oil and a polyhydric alcohol / water in a specific ratio in the ignitable silica. It is a thing.

The present invention also provides a method for producing a dentifrice composition, which comprises mixing polyoxyethylene hydrogenated castor oil in a polyhydric alcohol / water-based solution and then mixing ignitable silica. is there.

As the wetting agent used in the present invention, polyhydric alcohols such as sorbit, propylene glycol, glycerin and polyethylene glycol are used. These have a ratio of polyhydric alcohol to water of 1: 1.4 to 1:
It is most preferable that the compounding ratio is 2.2. If the ratio of water is less than 1.4, the viscosity will increase with the lapse of time, resulting in 2.2.
If it exceeds, separation will occur. The polyhydric alcohol content is preferably 25 to 40% by weight. If the amount is less than 25% by weight, the shape retention may be poor and the appearance may be impaired, and if it exceeds 40% by weight, the usability may be deteriorated.

The polyoxyethylene hydrogenated castor oil used in the present invention has an average added mole number of ethylene oxide of 4
It is preferably from 0 to 80, particularly preferably from 60 mol. The blending amount is 0.1 to 2% by weight, preferably 0.2 to 0.8%. If the content of polyoxyethylene hydrogenated castor oil is less than 0.1%, there will be a large change in viscosity, and if it exceeds 2% by weight, the polyoxyethylene hydrogenated castor oil will have an oily feel, resulting in a poor feeling in use. There is a problem of becoming.

[0008] The pyrogenic silica used in the present invention is selected variously, and among them, the specific surface area (BET) is particularly preferable.
Method) is preferably 175 to 225 m ² / g. When the specific surface area is 175 m ² / g or less, the shape retention is poor and 2
If it is at least 25 m ² / g, the viscosity will increase with time and it will be difficult to squeeze out of the container. Examples of the preferable igneous silica include Aerosil manufactured by Degussa, and Reolosil QS-20 manufactured by Tokuyama Soda. It is desirable that the ignitable silica is usually added in an amount of 1 to 4%, more preferably 2 to 3%. If it is 1% or less, the shape retention is poor, and if it is 4% or more, the viscosity increases over time, and it becomes difficult to squeeze out from the container. Further, the ignitable silica may be used in combination with the precipitated silica, and the one having a specific surface area (BET method) of 500 m ² / g or less, more preferably 300 m ² / g or less is preferred. Specifically, Huber's Zeo49, Zeodent1
13, W, R, Syloid AL of Grace
1, 63, 74, 404, etc., and one or more of these may be blended, but the blending amount is 1 to 20%.
It is preferable to mix, more preferably 5 to 15%.

Further, as a method for producing this dentifrice composition,
After mixing polyoxyethylene hydrogenated castor oil in a polyhydric alcohol / water-based solution, and then blending pyrogenic silica,
It is possible to obtain a product having less change in viscosity over time and good shape retention. If the polyoxyethylene hydrogenated castor oil is not mixed into the polyhydric alcohol / water solution before blending the fumed silica, the effect will be diminished.

The dentifrice composition of the present invention can be made into a dosage form such as a toothpaste according to a conventional method, and if necessary, appropriate components such as essential oils such as peppermint and spearmint, 1-
Fragrances such as menthol, carvone, anethole, and other flavoring materials, sweeteners such as sodium saccharin, stevioside, neohespiridyl hydrochalcone, glycyrrhizin, thaumatin, perillartine, P-methoxycinnamic aldehyde, sodium carboxyethyl cellulose, carrageenan, xanthan gum, sodium alginate. , A binder such as hydroxyethyl cellulose, and sodium fluoride, sodium monofluorophosphate, dextranase, mutanase, hinokitiol, lysozyme, allantoin, dipotassium glycyrrhizinate, epsilon aminocaproic acid, tranexamic acid, vitamin E and its derivatives, Active ingredients such as sodium chloride and azulene can be added within a range that does not impair the effects of the present invention.

[0011]

EXAMPLES The present invention will be described in more detail with reference to Examples and Experimental Examples. Experiment 1 In the formulation shown below, after mixing polyoxyethylene hydrogenated castor oil in a polyhydric alcohol / water-based solution,
A method of reacting the toothpaste prepared by the method of mixing the igneous silica (manufacturing method A) with the igneous silica in a polyhydric alcohol / water solution, and then blending polyoxyethylene hydrogenated castor oil (manufacturing method B). The toothpaste prepared in () was evaluated for viscosity change and property change after 1 month at room temperature. The viscosity was measured with a BH type viscometer at 30 ° C., and the change in viscosity was evaluated according to the following evaluation criteria. The properties were visually evaluated according to the following evaluation criteria. The results are shown in Table 1. Ingredient content (wt%) Pyrogenic silica 3.0 Precipitable silica 13.0 Sodium carboxymethyl cellulose 2.0 Sorbit liquid Water shown in Table 1 Perfume 1.3 Saccharin sodium 0.2 Polyoxyethylene curing Castor oil (60.EO) 0.5 Total 100.0% (Evaluation criteria) 1. Viscosity change ◯: The value of the viscosity after one month / the viscosity immediately after production is 1.0 or more and less than 1.3. Δ: The value of the viscosity after one month / the viscosity immediately after production is 1.3 or more and less than 2.0. X: The value of the viscosity after one month / the viscosity immediately after production is 2.0 or more. 2. Property change ○: Separation is not observed after 1 month. Δ: Some separation is observed after 1 month. ×: Separation is observed after 1 month. 3. Comprehensive evaluation ◯: Both viscosity and properties are ◯. Δ: There is Δ in either. X: There is x in either.

[0012]

[Table 1]

Experiment 2 A toothpaste prepared by mixing the additives shown in Table 2 in a polyhydric alcohol / water solution and then mixing the igneous silica with the igneous silica based on the production method A in the following formulation. Was adjusted. The ratio of the polyhydric alcohol and the water was as good as the result of Experiment 1, and was set to 1: 1.8, and the change in viscosity and the change in property after 1 month at room temperature were evaluated. The viscosity,
The change in viscosity, the change in properties and the overall evaluation were evaluated according to the same criteria as in Experiment 1. The results are shown in Table 2. Component content (wt%) Pyrogenic silica 3.0 Precipitable silica 13.0 Sodium carboxymethyl cellulose 2.0 Perfume 1.3 Saccharin sodium 0.2 Sorbit solution 28.0 Water 52.0 Additives Shown in Table 2 Total 100.0%

[0014]

[Table 2]

[0015]

EFFECTS OF THE INVENTION According to the present invention, a dentifrice composition having little change in viscosity over time and good shape retention can be obtained.

Claims (6)

[Claims] Claims: 1. A dentifrice composition containing a fumed silica, wherein polyoxyethylene hydrogenated castor oil in which the added mole number of ethylene oxide is 40 to 80 and 1: 1.4-.
A dentifrice composition comprising a polyhydric alcohol / water in a ratio of 1: 2.2. 2. A method for producing a dentifrice composition, which comprises mixing polyoxyethylene hydrogenated castor oil in a polyhydric alcohol / water-based solution and then mixing ignitable silica. 3. The specific surface area according to the BET method is 175 to 22.
The dentifrice composition according to claim 1 or 2, and a method for producing the same, which comprises using 5 m ² / g of ignitable silica. 4. The blending amount of the igneous silica is 1 to 4% by weight, and the blending amount of the polyoxyethylene hydrogenated castor oil is 0.
The dentifrice composition according to any one of claims 1 to 3 and the method for producing the dentifrice composition, wherein the content is 1 to 2% by weight and the polyhydric alcohol is 25 to 40% by weight. 5. The dentifrice composition according to claim 1, wherein a silica-based abrasive is blended as the abrasive, and the method for producing the same. 6. The dentifrice composition according to claim 1, wherein the dentifrice composition has a viscosity of 350 to 650 poise, and a method for producing the same.