JPH0737978B2 - 生育可能細胞の標識 - Google Patents

生育可能細胞の標識

Info

Publication number
JPH0737978B2
JPH0737978B2 JP62277256A JP27725687A JPH0737978B2 JP H0737978 B2 JPH0737978 B2 JP H0737978B2 JP 62277256 A JP62277256 A JP 62277256A JP 27725687 A JP27725687 A JP 27725687A JP H0737978 B2 JPH0737978 B2 JP H0737978B2
Authority
JP
Japan
Prior art keywords
cells
labeling
cell
dye
good
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62277256A
Other languages
English (en)
Japanese (ja)
Other versions
JPS63122954A (ja
Inventor
ポール・カール・ホーラン
ブルース・デイビッド・ジェンセン
シュー・エレン・スレザック
Original Assignee
スミスクライン・ベックマン・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スミスクライン・ベックマン・コーポレイション filed Critical スミスクライン・ベックマン・コーポレイション
Publication of JPS63122954A publication Critical patent/JPS63122954A/ja
Publication of JPH0737978B2 publication Critical patent/JPH0737978B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP62277256A 1986-10-31 1987-10-30 生育可能細胞の標識 Expired - Lifetime JPH0737978B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US925192 1986-10-31
US06/925,192 US4783401A (en) 1986-10-31 1986-10-31 Viable cell labelling

Publications (2)

Publication Number Publication Date
JPS63122954A JPS63122954A (ja) 1988-05-26
JPH0737978B2 true JPH0737978B2 (ja) 1995-04-26

Family

ID=25451357

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62277256A Expired - Lifetime JPH0737978B2 (ja) 1986-10-31 1987-10-30 生育可能細胞の標識

Country Status (15)

Country Link
US (1) US4783401A (da)
EP (1) EP0266194B1 (da)
JP (1) JPH0737978B2 (da)
KR (1) KR970000783B1 (da)
CN (1) CN1014547B (da)
AT (1) ATE110417T1 (da)
AU (1) AU606894B2 (da)
CA (1) CA1311685C (da)
DE (1) DE3750421T2 (da)
DK (1) DK175074B1 (da)
IE (1) IE69533B1 (da)
IL (1) IL84278A (da)
PH (1) PH23564A (da)
PT (1) PT86028B (da)
ZA (1) ZA878157B (da)

Families Citing this family (61)

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US4859584A (en) * 1986-10-31 1989-08-22 Smithkline Beckman Corporation Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes
ATE145337T1 (de) * 1988-05-02 1996-12-15 Phanos Tech Inc Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen
US5256532A (en) * 1988-05-02 1993-10-26 Zynaxis Technologies, Inc. Methods, reagents and test kits for determination of subpopulations of biological entities
US4963478A (en) * 1988-07-05 1990-10-16 Immucor, Inc. Article for preforming immunological assays utilizing organic dyes and method for producing and utilizing same
JPH02187661A (ja) * 1989-01-13 1990-07-23 J M L:Kk 網状赤血球の新染色法
US5169788A (en) * 1989-06-09 1992-12-08 New England Deaconess Hospital Corporation Methods of measuring membrane potential using j-aggregate forming dyes
US5279936A (en) * 1989-12-22 1994-01-18 Syntex (U.S.A.) Inc. Method of separation employing magnetic particles and second medium
US5375606A (en) * 1990-02-28 1994-12-27 Zynaxis, Inc. Bio-analytical separation method
US5242792A (en) * 1991-02-25 1993-09-07 The United States Of America As Represented By The Secretary Of The Navy Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides
WO1993002360A1 (en) * 1991-07-16 1993-02-04 Transmed Biotech Incorporated Methods and compositions for simultaneous analysis of multiple analytes
EP0643706A1 (en) * 1991-11-27 1995-03-22 Zynaxis Inc. Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles
US5334509A (en) * 1992-10-22 1994-08-02 Riordan Neil H Method for detecting intestinal pathogen dientamoeba fragilis
US5585246A (en) * 1993-02-17 1996-12-17 Biometric Imaging, Inc. Method for preparing a sample in a scan capillary for immunofluorescent interrogation
AU6365894A (en) * 1993-03-16 1994-10-11 Alliance Pharmaceutical Corporation Fluorocarbon compositions containing a visible or fluorescent label
ES2156927T3 (es) * 1994-10-20 2001-08-01 Sysmex Corp Reactivo y metodo para analizar componentes solidos en orina.
US6004536A (en) * 1995-11-14 1999-12-21 Molecular Probes, Inc. Lipophilic cyanine dyes with enchanced aqueous solubilty
US5804389A (en) * 1995-12-29 1998-09-08 Phanos Technologies, Inc. Method for detecting abnormal epithelial cell shedding
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US6008010A (en) * 1996-11-01 1999-12-28 University Of Pittsburgh Method and apparatus for holding cells
US6727071B1 (en) 1997-02-27 2004-04-27 Cellomics, Inc. System for cell-based screening
US7117098B1 (en) 1997-02-27 2006-10-03 Cellomics, Inc. Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm
CA2282658C (en) 1997-02-27 2003-02-25 Cellomics, Inc. A system for cell-based screening
US6858439B1 (en) * 1999-03-15 2005-02-22 Aviva Biosciences Compositions and methods for separation of moieties on chips
EP1163372A4 (en) * 1999-03-24 2002-10-02 Princeton Separations CHEMICALLY REACTIVE CYANINE DYES AND DERIVATIVES IN A LEVEL
US6986993B1 (en) * 1999-08-05 2006-01-17 Cellomics, Inc. System for cell-based screening
WO2001042786A2 (en) 1999-12-09 2001-06-14 Cellomics, Inc. System for cell based screening : cell spreading
US20090087450A1 (en) * 2000-01-11 2009-04-02 Greenville Hospital System Combination therapy of hybrid cells with BCG injection for treating Cancer Patients
DK1248836T3 (da) 2000-01-11 2005-08-15 Greenville Hospital System Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller
US20070212338A1 (en) * 2000-01-11 2007-09-13 Greenville Hospital System Hybrid cells
US20030223935A1 (en) * 2001-03-05 2003-12-04 Gray Brian D. Fluorescent membrane intercalating probes and methods for their use
AU2001245424B2 (en) * 2000-03-03 2005-08-18 Phanos Technologies, Inc. Fluorescent membrane intercalating probes and methods for their use
WO2002008454A2 (en) * 2000-07-24 2002-01-31 Genprime, Inc. Method and device for viable and nonviable prokaryotic and eukaryotic cell quantitation
WO2002012896A1 (en) * 2000-08-08 2002-02-14 Aviva Biosciences Corporation Methods for manipulating moieties in microfluidic systems
US7309581B2 (en) * 2000-11-01 2007-12-18 Sysmex Corporation Method of staining, detection and counting bacteria, and a diluent for bacterial stain
US6689391B2 (en) 2001-03-30 2004-02-10 Council Of Scientific & Industrial Research Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses
US20020159625A1 (en) * 2001-04-02 2002-10-31 Cytoprint, Inc. Method and apparatus for discovering, identifying and comparing biological activity mechanisms
EP1406492B1 (en) * 2001-06-06 2009-12-30 Perfusion Partners & Associates, Inc. Centrifuge tube assembly
US6955872B2 (en) * 2003-03-20 2005-10-18 Coulter International Corp. Dye compositions which provide enhanced differential fluorescence and light scatter characteristics
SI1656455T1 (sl) * 2003-08-13 2012-12-31 Sandoz Ag Postopek za čiščenje rekombinantnih polipeptidov
US7776529B2 (en) 2003-12-05 2010-08-17 Life Technologies Corporation Methine-substituted cyanine dye compounds
CA2560544C (en) 2004-01-16 2015-05-19 Carnegie Mellon University Cellular labeling for nuclear magnetic resonance techniques
US10858384B2 (en) 2004-03-22 2020-12-08 Kode Biotech Limited Synthetic molecule constructs
US7205145B2 (en) * 2004-03-24 2007-04-17 Zefon International, Inc. Gas-borne matter collection device
US20050266415A1 (en) * 2004-05-28 2005-12-01 Zefon International, Inc. Method for sampling gas-borne matter
US20060052324A1 (en) * 2004-08-05 2006-03-09 Artandi Steven E Methods and compositions for cell activation
JP5306811B2 (ja) 2005-05-11 2013-10-02 ライフ テクノロジーズ コーポレーション 2本鎖dnaへの高い選択性を有する蛍光化学物質及びそれらの使用
AU2005234696B2 (en) 2005-11-18 2012-02-16 Phanos Technologies, Inc. Fluorescent membrane intercalating probes and methods for their use
WO2008054509A2 (en) * 2006-04-14 2008-05-08 Celsense, Inc. Methods for assessing cell labeling
WO2007120911A2 (en) * 2006-04-14 2007-10-25 Carnegie Mellon University Cellular labeling and quantification for nuclear magnetic resonance techniques
ES2264403B1 (es) 2006-06-22 2007-11-01 Grifols S.A. Medio de suspension de hematies.
US20100203637A1 (en) * 2006-09-06 2010-08-12 Elena Korchagina Fluorescent cell markers
US7926368B2 (en) * 2006-11-01 2011-04-19 Zefon International, Inc. Humidity-controlled gas-borne matter collection device
CA2693678C (en) * 2007-07-10 2017-02-14 Carnegie Mellon University Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
US11266736B2 (en) 2008-04-17 2022-03-08 Vin De Bona Trading Company Pte Ltd Method of painting micro vesicles
US20110110863A1 (en) * 2008-05-02 2011-05-12 Celsense, Inc. Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
DE102008040513B4 (de) * 2008-07-17 2010-08-26 BAM Bundesanstalt für Materialforschung und -prüfung Verwendung einer langwellig emittierenden Cyaninverbindung als NIR-Fluoreszenzstandard und Kit zur Kalibrierung von Photolumineszenzmesssystemen
CN104685346B (zh) 2012-05-02 2018-05-29 查尔斯河实验室公司 细胞捕获系统及其使用
CA2872149C (en) 2012-05-02 2019-03-19 Charles River Laboratories, Inc. Viability staining method
CN104755931B (zh) 2012-05-02 2016-08-31 查尔斯河实验室公司 用于检测细胞样品中的活细胞的方法
DK2906717T3 (da) 2012-10-11 2019-04-01 Vin De Bona Trading Company Pte Ltd Fremgangsmåde til maling af mikrovesikler
EP4492037A1 (en) * 2023-07-10 2025-01-15 Sysmex Corporation Method for detecting platelet aggregation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4232121A (en) * 1978-09-25 1980-11-04 Eastman Kodak Company Process for selecting methine dyes which inhibit cell growth
US4424201A (en) * 1978-11-28 1984-01-03 Rockefeller University Employment of a mereyanine dye for the detection of malignant leukocytic cells
US4400370A (en) * 1980-03-12 1983-08-23 Lawrence Kass Metachromatic dye sorption means for differential determination of leukocytes
US4581223A (en) * 1980-03-12 1986-04-08 Lawrence Kass Individual leukocyte determination by means of differential metachromatic dye sorption
DE3238353A1 (de) * 1982-10-15 1984-04-19 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer
US4555396A (en) * 1982-12-22 1985-11-26 Eastman Kodak Company Use of pyrylium and thiapyrylium compounds as biological stains
JPH06100596B2 (ja) * 1986-09-10 1994-12-12 東亜医用電子株式会社 フロ−サイトメトリ−による白血球の分類方法

Also Published As

Publication number Publication date
ATE110417T1 (de) 1994-09-15
PT86028A (en) 1987-11-01
CN87107216A (zh) 1988-05-11
EP0266194B1 (en) 1994-08-24
IE69533B1 (en) 1996-09-18
EP0266194A2 (en) 1988-05-04
IE872872L (en) 1988-04-30
DE3750421T2 (de) 1995-03-16
DK570387D0 (da) 1987-10-30
US4783401A (en) 1988-11-08
KR880005456A (ko) 1988-06-29
DK175074B1 (da) 2004-05-24
EP0266194A3 (en) 1988-08-03
CA1311685C (en) 1992-12-22
ZA878157B (en) 1988-08-31
JPS63122954A (ja) 1988-05-26
DK570387A (da) 1988-05-01
KR970000783B1 (ko) 1997-01-20
IL84278A (en) 1992-07-15
AU8040387A (en) 1988-05-05
CN1014547B (zh) 1991-10-30
IL84278A0 (en) 1988-03-31
DE3750421D1 (de) 1994-09-29
PH23564A (en) 1989-08-25
AU606894B2 (en) 1991-02-21
PT86028B (pt) 1990-08-31

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