JPH07509237A - ｇｐ１２０ＨＩＶエピトープを模倣したペプチド - Google Patents

ｇｐ１２０ＨＩＶエピトープを模倣したペプチド

Info

Publication number
JPH07509237A
JPH07509237A JP6504265A JP50426593A JPH07509237A JP H07509237 A JPH07509237 A JP H07509237A JP 6504265 A JP6504265 A JP 6504265A JP 50426593 A JP50426593 A JP 50426593A JP H07509237 A JPH07509237 A JP H07509237A
Authority
JP
Japan
Prior art keywords
molecule according
peptide
hiv
molecule
peptide sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6504265A
Other languages
English (en)
Japanese (ja)
Inventor
バトラー，ピーター・ジョナサン・ガスキング
ハッキング，グレーム・ノーマン・バーレイ
Original Assignee
メディカル・リサーチ・カウンシル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メディカル・リサーチ・カウンシル filed Critical メディカル・リサーチ・カウンシル
Publication of JPH07509237A publication Critical patent/JPH07509237A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pressure Welding/Diffusion-Bonding (AREA)
JP6504265A 1992-07-16 1993-07-16 ｇｐ１２０ＨＩＶエピトープを模倣したペプチド Pending JPH07509237A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929215129A GB9215129D0 (en) 1992-07-16 1992-07-16 Development relating to human immunodeficiency viruses
GB9215129.9 1992-07-16
PCT/GB1993/001503 WO1994002614A1 (en) 1992-07-16 1993-07-16 PEPTIDES THAT MIMIC gp120 HIV EPITOPE

Publications (1)

Publication Number Publication Date
JPH07509237A true JPH07509237A (ja) 1995-10-12

Family

ID=10718806

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6504265A Pending JPH07509237A (ja) 1992-07-16 1993-07-16 ｇｐ１２０ＨＩＶエピトープを模倣したペプチド

Country Status (7)

Country Link
EP (1) EP0654080A1 (de)
JP (1) JPH07509237A (de)
AU (1) AU681591B2 (de)
CA (1) CA2140151A1 (de)
GB (1) GB9215129D0 (de)
WO (1) WO1994002614A1 (de)
ZA (1) ZA935165B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4402756A1 (de) * 1994-01-31 1995-08-03 Boehringer Mannheim Gmbh Spezifische Bindungssubstanzen für Antikörper und deren Verwendung für Immunoassays oder Vakzine
US6911527B1 (en) 1999-01-11 2005-06-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services HIV related peptides
EP1159297A2 (de) * 1999-01-11 2001-12-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Hiv-verwandte peptide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714802D0 (en) * 1987-06-24 1987-07-29 Proteus Biotech Ltd Synthetic polypeptides
FR2617944B1 (fr) * 1987-07-06 1990-09-28 Macc Sa Perfectionnement aux chevalets
GB8828097D0 (en) * 1988-12-01 1989-01-05 Wellcome Found Peptides
CA2035576A1 (en) * 1990-02-07 1991-08-08 Alexander R. Neurath Conformational epitopes of human immunodeficiency virus envelope glycoprotein gp120 hiv-1

Also Published As

Publication number Publication date
WO1994002614A1 (en) 1994-02-03
CA2140151A1 (en) 1994-02-03
ZA935165B (en) 1994-03-14
EP0654080A1 (de) 1995-05-24
AU4578893A (en) 1994-02-14
GB9215129D0 (en) 1992-08-26
AU681591B2 (en) 1997-09-04

Similar Documents

Publication Publication Date Title
Rusche et al. Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.
Palker et al. Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.
US5019387A (en) Production of antibodies to HIV
AU693098B2 (en) Tandem synthetic HIV-1 peptides
US5013548A (en) Production of antibodies to HIV
EP0328403B1 (de) Synthetische vom HIV-GP120-env-Protein abgeleitete Peptide und ihre Anwendung
Shafferman et al. Protection of macaques with a simian immunodeficiency virus envelope peptide vaccine based on conserved human immunodeficiency virus type 1 sequences.
US7172761B2 (en) Polyvalent immunogen
US7195768B2 (en) Polyvalent immunogen
EP0436634A1 (de) Hiv-proteine und peptide und deren verwendung zur diagnose, prophylaxe und therapie von aids
JPH06501260A (ja) ヒト免疫不全ウィルスに対する中和抗体の誘発とワクチン接種に用いられるペプチド
EP0519986A1 (de) Synthetische polypeptide
AU707894B2 (en) Synthetic vaccine for protection against human immunodeficiency virus infection
Conley et al. Immunogenicity of synthetic HIV-1 gp120 V3-loop peptide-conjugate immunogens
JPH03128399A (ja) エイズ用複合免疫原
US5820865A (en) Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides
US6080846A (en) Composition containing a B epitope of the envelope glycoprotein of a retrovirus and a T epitope of another distinct protein of this retrovirus
US5688914A (en) Composition containing a B epitope of the envelope glycoprotein of a retrovirus and a T epitope of another distinct protein of this retrovirus
JPH07509237A (ja) ｇｐ１２０ＨＩＶエピトープを模倣したペプチド
WO1993025235A1 (en) Aids therapeutics based on hiv-2 vpx peptides
Lynch et al. Advances in HTLV-1 peptide vaccines and therapeutics
CA2262427A1 (en) Conjugated peptides, immunological reagent containing same and use thereof for treatment of immunological disorders
Wagner et al. Immunological reactivity of a human immunodeficiency virus type I derived peptide representing a consensus sequence of the GP 120 major neutralizing region V3
JPH09500096A (ja) ヒト免疫不全ウイルスに対する予防接種および中和抗体誘発に用いられるペプチド
Wolf et al. Fine specificity of the murine antibody response to HIV-1 gp160 determined by synthetic peptides which define selected epitopes