JPH09506260A - メトトレキサートを検出するための試薬および方法 - Google Patents

メトトレキサートを検出するための試薬および方法

Info

Publication number
JPH09506260A
JPH09506260A JP7516209A JP51620995A JPH09506260A JP H09506260 A JPH09506260 A JP H09506260A JP 7516209 A JP7516209 A JP 7516209A JP 51620995 A JP51620995 A JP 51620995A JP H09506260 A JPH09506260 A JP H09506260A
Authority
JP
Japan
Prior art keywords
methotrexate
antibody
cell line
reactivity
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP7516209A
Other languages
English (en)
Japanese (ja)
Inventor
タイナー，ジヨウン・デイー
ジユーブランド，シエリ・エル
Original Assignee
アボツト・ラボラトリーズ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アボツト・ラボラトリーズ filed Critical アボツト・ラボラトリーズ
Publication of JPH09506260A publication Critical patent/JPH09506260A/ja
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP7516209A 1993-12-10 1994-11-22 メトトレキサートを検出するための試薬および方法 Ceased JPH09506260A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16512193A 1993-12-10 1993-12-10
US08/165,121 1993-12-10
PCT/US1994/013558 WO1995016026A1 (fr) 1993-12-10 1994-11-22 Reactifs et procedes de detection du methotrexate

Publications (1)

Publication Number Publication Date
JPH09506260A true JPH09506260A (ja) 1997-06-24

Family

ID=22597511

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7516209A Ceased JPH09506260A (ja) 1993-12-10 1994-11-22 メトトレキサートを検出するための試薬および方法

Country Status (5)

Country Link
EP (1) EP0733102A1 (fr)
JP (1) JPH09506260A (fr)
AU (1) AU1186695A (fr)
CA (1) CA2178590A1 (fr)
WO (1) WO1995016026A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710009A (en) * 1994-02-17 1998-01-20 Serex, Inc. Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon
AU2678997A (en) * 1996-04-19 1997-11-12 Lexigen Pharmaceuticals Corp. Inhibition of the binding of human ige to its receptor by tetracyclic compounds for the alleviation of ige-mediated immune response
EP3002299A1 (fr) 2008-06-03 2016-04-06 AbbVie Inc. Immunoglobulines à deux domaines variables et leurs utilisations
AR078254A1 (es) * 2009-09-01 2011-10-26 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
US8735546B2 (en) 2010-08-03 2014-05-27 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
PH12013500337A1 (en) 2010-08-26 2017-08-23 Abbvie Inc Dual variable domain immunoglobulins and uses thereof
US9120870B2 (en) 2011-12-30 2015-09-01 Abbvie Inc. Dual specific binding proteins directed against IL-13 and IL-17
AU2013337775B2 (en) 2012-11-01 2017-03-30 Abbvie Inc. Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof
EP2970459A2 (fr) 2013-03-15 2016-01-20 AbbVie Inc. Protéines de liaison spécifiques à domaines variables doubles dirigées contre il -1beta et il -17
US10093733B2 (en) 2014-12-11 2018-10-09 Abbvie Inc. LRP-8 binding dual variable domain immunoglobulin proteins
CN104569373B (zh) * 2015-01-27 2016-08-17 苏州博源医疗科技有限公司 一种甲氨蝶呤均相酶免疫检测试剂及其制备和检测方法
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
US10675364B2 (en) * 2015-06-23 2020-06-09 The Board Of Trustees Of The Leland Stanford Junior University Rhodol fluorophores for near-infrared imaging
WO2017007889A1 (fr) * 2015-07-08 2017-01-12 Defined Diagnostics, Llc Composés et méthodes pour la détection du méthotrexate
CN108614107A (zh) * 2016-12-12 2018-10-02 上海复星长征医学科学有限公司 一种甲氨蝶呤胶乳免疫比浊测定试剂盒及其制备方法
CN107219357B (zh) * 2017-04-21 2020-07-07 中国人民解放军第三军医大学第一附属医院 一种检测甲氨蝶呤的elisa试剂盒及其应用
CN110357886B (zh) * 2018-04-09 2022-06-24 浙江准策生物技术有限公司 甲氨蝶呤半抗原和完全抗原及其制备方法和应用

Also Published As

Publication number Publication date
WO1995016026A1 (fr) 1995-06-15
CA2178590A1 (fr) 1995-06-15
AU1186695A (en) 1995-06-27
EP0733102A1 (fr) 1996-09-25

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