JPH09509562A - 新規なタンパク質／ポリペプチド及びコトランスフェクションプラスミド並びにその組換え生キャリヤー - Google Patents

新規なタンパク質／ポリペプチド及びコトランスフェクションプラスミド並びにその組換え生キャリヤー

Info

Publication number
JPH09509562A
JPH09509562A JP7508961A JP50896195A JPH09509562A JP H09509562 A JPH09509562 A JP H09509562A JP 7508961 A JP7508961 A JP 7508961A JP 50896195 A JP50896195 A JP 50896195A JP H09509562 A JPH09509562 A JP H09509562A
Authority
JP
Japan
Prior art keywords
protein
coronavirus
modified
region
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7508961A
Other languages
English (en)
Japanese (ja)
Inventor
ミッシェル ビューブロ
ワナメイカー カテリーヌ ド
ディディエール コロー
サランビアン フィリップ ルー
Original Assignee
ソルヴェイ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソルヴェイ filed Critical ソルヴェイ
Publication of JPH09509562A publication Critical patent/JPH09509562A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP7508961A 1993-09-16 1994-09-07 新規なタンパク質／ポリペプチド及びコトランスフェクションプラスミド並びにその組換え生キャリヤー Pending JPH09509562A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9319212.8 1993-09-16
GB9319212A GB2282601B (en) 1993-09-16 1993-09-16 Antigenically-active proteins/polypeptides and coronavirus vaccines containing the same
PCT/EP1994/002990 WO1995007987A2 (fr) 1993-09-16 1994-09-07 Nouveaux polypeptides/proteines, plasmides de cotransfection et leurs vecteurs recombinants vivants

Publications (1)

Publication Number Publication Date
JPH09509562A true JPH09509562A (ja) 1997-09-30

Family

ID=10742112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7508961A Pending JPH09509562A (ja) 1993-09-16 1994-09-07 新規なタンパク質／ポリペプチド及びコトランスフェクションプラスミド並びにその組換え生キャリヤー

Country Status (10)

Country Link
EP (1) EP0720654A1 (fr)
JP (1) JPH09509562A (fr)
KR (1) KR960705047A (fr)
AU (1) AU7615894A (fr)
BR (1) BR9407507A (fr)
CA (1) CA2171869A1 (fr)
GB (2) GB2282601B (fr)
NO (1) NO961086L (fr)
WO (1) WO1995007987A2 (fr)
ZA (1) ZA946887B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724385B1 (fr) * 1994-08-29 1996-12-13 Rhone Merieux Vaccin de la peritonite infectieuse feline.
FR2741806B1 (fr) * 1995-11-30 1998-02-20 Rhone Merieux Vaccin vivant recombinant a base d'herpesvirus felin de type 1, notamment contre la peritonite infectieuse feline
AU3650197A (en) * 1996-07-05 1998-02-02 Vanderbilt University Mutated antibody-dependent infection enhancing domains of hiv
FR2751223B1 (fr) * 1996-07-19 1998-12-04 Rhone Merieux Formule de vaccin polynucleotidique felin
CN1223605C (zh) * 2003-05-16 2005-10-19 中国科学院微生物研究所 抑制sars冠状病毒的多肽药物及其衍生物和其应用
CN113321714B (zh) * 2020-02-28 2022-12-09 深圳市亚辉龙生物科技股份有限公司 SARS-CoV-2的重组N蛋白及其制备与纯化方法
WO2022055978A1 (fr) * 2020-09-08 2022-03-17 The Trustees Of The University Of Pennsylvania Compositions et méthodes de diminution de risque de maladie amplifiée par vaccin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76751A (en) * 1984-11-01 1991-04-15 American Home Prod Method and oral vaccines against infectious organisms using live,recombinant adenovirus for the production of antibodies
JPS63123385A (ja) * 1986-09-05 1988-05-27 デュファル・インテルナチオナル・レセールフ・ベー・ヴェー 新規抗原的活性蛋白質およびぺプチド、並びにネコ科感染性腹膜炎ウイルスワクチン
CA2005291C (fr) * 1988-12-30 1999-01-26 Beverly Dale Instruments de diagnostic du virus de la peritonite infectieuse des felins
HUT54733A (en) * 1989-07-12 1991-03-28 Duphar Int Res Process for producing new, antigenically active proteins and peptides, as well as feline infectious peritonitis virus (fipv) vaccines
NZ240558A (en) * 1990-11-14 1994-11-25 Smithkline Beecham Corp Recombinant feline coronavirus s proteins useful in diagnosis and vaccination against feline peritonitis virus disease
CA2128698A1 (fr) * 1992-02-18 1993-08-19 Richard G. Olsen Vaccin contre la peritonite feline infectieuse et methode de preparation
ES2182827T3 (es) * 1992-05-08 2003-03-16 Pfizer Gen del virus corona canino y usos del mismo.
JPH07508176A (ja) * 1992-05-08 1995-09-14 ファイザー・インコーポレイテッド 普遍コロナウイルスワクチン

Also Published As

Publication number Publication date
GB2282601A (en) 1995-04-12
BR9407507A (pt) 1997-01-07
EP0720654A1 (fr) 1996-07-10
WO1995007987A2 (fr) 1995-03-23
GB2316681A (en) 1998-03-04
ZA946887B (en) 1995-06-27
WO1995007987A3 (fr) 1995-06-22
AU7615894A (en) 1995-04-03
NO961086L (no) 1996-05-09
GB2282601B (en) 1998-04-15
GB2316681B (en) 1998-04-15
GB9319212D0 (en) 1993-11-03
CA2171869A1 (fr) 1995-03-23
NO961086D0 (no) 1996-03-15
KR960705047A (ko) 1996-10-09
GB9722558D0 (en) 1997-12-24

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