JPH10500978A - ｐ５３タンパク質の調節による腫瘍の治療方法 - Google Patents

ｐ５３タンパク質の調節による腫瘍の治療方法

Info

Publication number
JPH10500978A
JPH10500978A JP8500420A JP50042096A JPH10500978A JP H10500978 A JPH10500978 A JP H10500978A JP 8500420 A JP8500420 A JP 8500420A JP 50042096 A JP50042096 A JP 50042096A JP H10500978 A JPH10500978 A JP H10500978A
Authority
JP
Japan
Prior art keywords
protein
nucleic acid
calpain
vector
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8500420A
Other languages
English (en)
Japanese (ja)
Inventor
ジヤン−マリー ブランシヤール，
セルジユ カリヨ，
マルク ピエシヤクジク，
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH10500978A publication Critical patent/JPH10500978A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP8500420A 1994-05-31 1995-05-22 ｐ５３タンパク質の調節による腫瘍の治療方法 Pending JPH10500978A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/06583 1994-05-31
FR9406583A FR2720277B1 (fr) 1994-05-31 1994-05-31 Méthode de traitement des cancers par régulation de la protéine P53.
PCT/FR1995/000670 WO1995033060A1 (fr) 1994-05-31 1995-05-22 Methode de traitement des cancers par regulation de la proteine p53

Publications (1)

Publication Number Publication Date
JPH10500978A true JPH10500978A (ja) 1998-01-27

Family

ID=9463670

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8500420A Pending JPH10500978A (ja) 1994-05-31 1995-05-22 ｐ５３タンパク質の調節による腫瘍の治療方法

Country Status (8)

Country Link
EP (1) EP0763121A1 (fr)
JP (1) JPH10500978A (fr)
AU (1) AU714209B2 (fr)
CA (1) CA2190293C (fr)
FI (1) FI120501B (fr)
FR (1) FR2720277B1 (fr)
NO (1) NO321411B1 (fr)
WO (1) WO1995033060A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518488C1 (de) * 1995-05-19 1996-10-10 Progen Biotechnik Gmbh Autoantigen, geeignet zur Feststellung einer Thromboseneigung
EP0799892A3 (fr) * 1996-04-05 1998-08-12 Takeda Chemical Industries, Ltd. Calpain, sa préparation et son utilisation
US6232454B1 (en) * 1998-02-27 2001-05-15 Incyte Genomics, Inc. Human proteinase molecules
JP2002530085A (ja) * 1998-11-18 2002-09-17 カンジ，インコーポレイテッド 後期導入遺伝子の発現を有するウイルスベクター
WO2001074381A2 (fr) * 2000-03-31 2001-10-11 Parker Hughes Institute Inhibiteurs de calpaines pour le traitement du cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753665B2 (ja) * 1984-04-20 1995-06-07 財団法人癌研究会 抗転移剤
US5340922B1 (en) * 1988-05-31 1999-11-02 Mclean Hospital Corp Neural calcium-activated neutral proteinase inhibitors
EP0395309B1 (fr) * 1989-04-28 1995-12-27 Takara Shuzo Co. Ltd. Polypeptide semblable à la calpastatine humaine
JPH0641067A (ja) * 1992-04-20 1994-02-15 Kitasato Inst:The 新規カルパイン阻害物質ｋｐ−１２４１及びその製造法
EP0580161A1 (fr) * 1992-07-22 1994-01-26 THE McLEAN HOSPITAL CORPORATION Traitement prophylactique et thérapeutique de la maladie d'Alzheimer
US5607831A (en) * 1993-03-25 1997-03-04 The United States Of America As Represented By The Department Of Health And Human Services In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death

Also Published As

Publication number Publication date
WO1995033060A1 (fr) 1995-12-07
CA2190293C (fr) 2011-06-28
FI964783L (fi) 1996-11-29
NO964772L (no) 1996-11-11
AU2620695A (en) 1995-12-21
FR2720277A1 (fr) 1995-12-01
NO321411B1 (no) 2006-05-08
FI120501B (fi) 2009-11-13
FR2720277B1 (fr) 1996-07-12
FI964783A0 (fi) 1996-11-29
AU714209B2 (en) 1999-12-23
EP0763121A1 (fr) 1997-03-19
CA2190293A1 (fr) 1995-12-07
NO964772D0 (no) 1996-11-11

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