JPH11507017A5 - - Google Patents

Info

Publication number
JPH11507017A5
JPH11507017A5 JP1996534120A JP53412096A JPH11507017A5 JP H11507017 A5 JPH11507017 A5 JP H11507017A5 JP 1996534120 A JP1996534120 A JP 1996534120A JP 53412096 A JP53412096 A JP 53412096A JP H11507017 A5 JPH11507017 A5 JP H11507017A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1996534120A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11507017A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1996/006119 external-priority patent/WO1996035678A1/en
Publication of JPH11507017A publication Critical patent/JPH11507017A/ja
Publication of JPH11507017A5 publication Critical patent/JPH11507017A5/ja
Withdrawn legal-status Critical Current

Links

JP8534120A 1995-05-08 1996-05-03 ウイルス逆転写酵素の阻害剤としてのα−置換のピリミジン−チオアルキルおよびアルキルエーテル化合物 Withdrawn JPH11507017A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43670895A 1995-05-08 1995-05-08
US08/436,708 1995-05-08
PCT/US1996/006119 WO1996035678A1 (en) 1995-05-08 1996-05-03 Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase

Publications (2)

Publication Number Publication Date
JPH11507017A JPH11507017A (ja) 1999-06-22
JPH11507017A5 true JPH11507017A5 (2) 2004-07-08

Family

ID=23733510

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8534120A Withdrawn JPH11507017A (ja) 1995-05-08 1996-05-03 ウイルス逆転写酵素の阻害剤としてのα−置換のピリミジン−チオアルキルおよびアルキルエーテル化合物

Country Status (26)

Country Link
US (1) US6043248A (2)
EP (2) EP0824524B1 (2)
JP (1) JPH11507017A (2)
KR (1) KR100445498B1 (2)
CN (2) CN1535958A (2)
AT (1) ATE275550T1 (2)
AU (1) AU712404B2 (2)
BR (1) BR9608265A (2)
CA (1) CA2216099C (2)
CZ (1) CZ293135B6 (2)
DE (1) DE69633332T2 (2)
ES (1) ES2227586T3 (2)
GE (1) GEP20002297B (2)
HU (1) HUP9801995A3 (2)
IL (1) IL118075A0 (2)
MX (1) MX9708582A (2)
NO (1) NO310287B1 (2)
NZ (1) NZ307089A (2)
PL (1) PL323240A1 (2)
PT (1) PT824524E (2)
RU (1) RU2167155C2 (2)
SK (1) SK150297A3 (2)
TW (1) TW450962B (2)
UA (1) UA56992C2 (2)
WO (1) WO1996035678A1 (2)
ZA (1) ZA963281B (2)

Families Citing this family (33)

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NZ503586A (en) * 1997-09-25 2002-03-28 Upjohn Co Thioalkyl alpha substituted pyrimidine compounds for treating HIV.
US6111111A (en) 1997-10-23 2000-08-29 Kuraray Co., Ltd. Intermediates for producing pyridine derivatives
US7358254B2 (en) 2001-07-13 2008-04-15 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an aP2 inhibitor and combination
GEP20033044B (en) 1998-09-17 2003-08-25 Bristol Myers Squibb Co Method for Treating Atherosclerosis
JP2003503354A (ja) 1999-06-30 2003-01-28 メルク エンド カムパニー インコーポレーテッド Ｓｒｃキナーゼ阻害剤化合物
AU5636900A (en) 1999-06-30 2001-01-31 Merck & Co., Inc. Src kinase inhibitor compounds
WO2001000207A1 (en) 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
US7138404B2 (en) * 2001-05-23 2006-11-21 Hoffmann-La Roche Inc. 4-aminopyrimidine derivatives
MX2007006635A (es) * 2004-12-03 2007-06-19 Merck & Co Inc Formulacion farmaceutica de inhibidores dela carboxamida vih integrasa que contienen una composicion que controla la velocidad de liberacion.
RU2401261C2 (ru) * 2005-03-04 2010-10-10 Тиботек Фармасьютикалз Лтд. Ингибирующие вич 2-(4-цианофенил)-6-гидроксиламинопиримидины
US7923056B2 (en) 2007-06-01 2011-04-12 Illinois Tool Works Inc. Method and apparatus for dispensing material on a substrate
US9040538B2 (en) 2009-05-21 2015-05-26 Universite Laval Pyrimidines as novel therapeutic agents
CN101638391B (zh) * 2009-08-21 2011-04-27 山东大学 2-[(取代苯氨基)羰基甲硫基]-6-(2,6-二氯苄基)-3h-嘧啶-4-酮类衍生物及其制备方法与应用
US9226970B2 (en) 2010-02-22 2016-01-05 Nektar Therapeutics Oligomer modified diaromatic substituted compounds
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
TWI453208B (zh) * 2010-07-02 2014-09-21 Gilead Sciences Inc 治療性化合物類
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
KR101360587B1 (ko) * 2012-11-01 2014-03-10 현대자동차주식회사 스마트 도어 언록 시스템
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3324977B1 (en) 2015-07-22 2022-07-13 Enanta Pharmaceuticals, Inc. Benzodiazepine derivatives as rsv inhibitors
GB201807898D0 (en) * 2018-05-15 2018-06-27 Kancera Ab New processes and products with increased chiral purity
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
WO2021066922A1 (en) * 2019-10-04 2021-04-08 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
WO2021149051A1 (en) * 2020-01-20 2021-07-29 Agrematch Ltd. Compositions for crop protection
KR20240056718A (ko) 2021-08-10 2024-04-30 아이에프엠 듀, 인크. Sting 활성과 연합된 상태를 치료하기 위한 화합물 및 조성물
CN114057707A (zh) * 2021-11-24 2022-02-18 上海应用技术大学 一种n-4-吲哚基-2-呋喃甲酰胺化合物的制备方法
JP2025504415A (ja) * 2022-01-12 2025-02-12 アイエフエム デュー インコーポレイテッド Ｓｔｉｎｇ活性に関連する病態を治療するための化合物及び組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2295560A (en) * 1941-06-18 1942-09-15 Gen Electric Pyrimidine derivatives
GB744867A (en) * 1952-10-29 1956-02-15 American Cyanamid Co Improvements relating to 2-substituted-mercapto-4-amino-6-disubstituted-aminopyrimidines and acid addition salts thereof
US3940394A (en) * 1972-03-31 1976-02-24 Santilli Arthur A 2-pyrimidinylthio)alkanoic acids, esters, amides and hydrazides
US3940240A (en) * 1974-07-11 1976-02-24 Ina Seito Co., Ltd. Baking method and kiln for tile
EP0124630B1 (de) * 1983-05-05 1987-01-28 LUDWIG HEUMANN & CO GMBH Pyrimidin-Thioalkylpyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindung enthaltende Arzneimittel
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
JPS62209062A (ja) * 1986-03-10 1987-09-14 Yamanouchi Pharmaceut Co Ltd ２−ピリジルメチルチオ−または２−ピリジルメチルスルフイニル−置換縮合環化合物
JPH07107056B2 (ja) * 1987-01-30 1995-11-15 日清製粉株式会社 ４（３ｈ）−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤
WO1989011279A1 (en) * 1988-05-16 1989-11-30 Georgia State University Foundation, Inc. Nucleic acid interacting unfused heteropolycyclic compounds
HU203736B (en) * 1989-04-06 1991-09-30 Gyogyszerkutato Intezet Process for producing new thiouracil-derivatives and pharmaceutical compositions containing them
MX9203454A (es) * 1989-12-28 1992-08-01 Upjohn Co Compuestos anti sida diaromaticos substituidos.
US5668136A (en) * 1990-09-25 1997-09-16 Eisai Co., Ltd. Trisubstituted benzene derivatives, composition and methods of treatment
EP0594702B1 (en) * 1991-07-03 1997-01-29 PHARMACIA & UPJOHN COMPANY Substituted indoles as anti-aids pharmaceuticals
GB2266716A (en) * 1992-05-05 1993-11-10 Merck & Co Inc Inhibitors of HIV reverse transcriptase
JP3077046B2 (ja) * 1992-08-31 2000-08-14 久光製薬株式会社 新規なキナゾリン誘導体
US5977169A (en) * 1993-09-17 1999-11-02 Chrusciel; Robert A. Substituted tetronic acids useful for treating HIV and other retroviruses
US5981537A (en) * 1993-11-12 1999-11-09 Pharmacia & Upjohn Company Pyrimidine-thioalkyl and alkylether compounds
US5945425A (en) * 1994-04-29 1999-08-31 G.D. Searle & Co. Method of using (H+ /K+)ATPase inhibitors as antiviral agents
JPH10502660A (ja) * 1994-07-20 1998-03-10 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング ヘリコバクター細菌に対抗するためのピリジルチオ化合物

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