JPH11507036A - ジカチオン性ビス−ベンズイミダゾール類を用いた感染病治療方法 - Google Patents

ジカチオン性ビス−ベンズイミダゾール類を用いた感染病治療方法

Info

Publication number: JPH11507036A
Authority: JP; Japan
Prior art keywords: bis; benzimidazolyl; structural formula; following structural; lower alkyl
Prior art date: 1995-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

JP9500868A

Other languages

English (en)

Japanese (ja)

Other versions

JPH11507036A5 (2

Inventor

ダイクストラ，クリスティン・シー

パーフェクト，ジョン・アール

ボイキン，デイヴィッド・ダブリュー

ウィルソン，ダブリュー・デイヴィッド

ティドウェル，リチャード・アール

Original Assignee

ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル

デューク・ユニヴァーシティ

ジョージア・ステイト・ユニヴァーシティ・リサーチ・ファンデイション，インコーポレイテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-07

Filing date

1996-06-03

Publication date

1999-06-22

1996-06-03 Application filed by ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル, デューク・ユニヴァーシティ, ジョージア・ステイト・ユニヴァーシティ・リサーチ・ファンデイション，インコーポレイテッド filed Critical ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル

1999-06-22 Publication of JPH11507036A publication Critical patent/JPH11507036A/ja

2004-07-22 Publication of JPH11507036A5 publication Critical patent/JPH11507036A5/ja

Status Ceased legal-status Critical Current

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

JP9500868A 1995-06-07 1996-06-03 ジカチオン性ビス−ベンズイミダゾール類を用いた感染病治療方法 Ceased JPH11507036A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/472,996 US5643935A (en)	1995-06-07	1995-06-07	Method of combatting infectious diseases using dicationic bis-benzimidazoles
US08/472,996		1995-06-07
PCT/US1996/008084 WO1996040145A1 (en)	1995-06-07	1996-06-03	Methods of combatting infectious diseases using dicationic bis-benzimidazoles

Publications (2)

Publication Number	Publication Date
JPH11507036A true JPH11507036A (ja)	1999-06-22
JPH11507036A5 JPH11507036A5 (2)	2004-07-22

Family

ID=23877744

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP9500868A Ceased JPH11507036A (ja)	1995-06-07	1996-06-03	ジカチオン性ビス−ベンズイミダゾール類を用いた感染病治療方法

Country Status (9)

Country	Link
US (11)	US5643935A (2)
EP (1)	EP0831832B1 (2)
JP (1)	JPH11507036A (2)
AT (1)	ATE256464T1 (2)
AU (1)	AU705261B2 (2)
CA (1)	CA2223912A1 (2)
DE (1)	DE69631134T2 (2)
ES (1)	ES2213775T3 (2)
WO (1)	WO1996040145A1 (2)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
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1995
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1996
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- 1996-06-03 WO PCT/US1996/008084 patent/WO1996040145A1/en not_active Ceased
- 1996-06-03 ES ES96916817T patent/ES2213775T3/es not_active Expired - Lifetime
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- 1996-06-03 AT AT96916817T patent/ATE256464T1/de not_active IP Right Cessation
- 1996-06-03 DE DE69631134T patent/DE69631134T2/de not_active Expired - Fee Related
1997
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1998
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Also Published As

Publication number	Publication date
DE69631134D1 (de)	2004-01-29
US6294565B1 (en)	2001-09-25
US5792782A (en)	1998-08-11
ES2213775T3 (es)	2004-09-01
US5972969A (en)	1999-10-26
US6017941A (en)	2000-01-25
AU5956696A (en)	1996-12-30
EP0831832B1 (en)	2003-12-17
WO1996040145A1 (en)	1996-12-19
US5639755A (en)	1997-06-17
US6046226A (en)	2000-04-04
US6156779A (en)	2000-12-05
US5817686A (en)	1998-10-06
AU705261B2 (en)	1999-05-20
ATE256464T1 (de)	2004-01-15
DE69631134T2 (de)	2004-09-02
US5643935A (en)	1997-07-01
CA2223912A1 (en)	1996-12-19
US5817687A (en)	1998-10-06
US5939440A (en)	1999-08-17
EP0831832A4 (en)	1999-07-07
EP0831832A1 (en)	1998-04-01

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