JPH11511113A5 - - Google Patents
Info
- Publication number
- JPH11511113A5 JPH11511113A5 JP1996531337A JP53133796A JPH11511113A5 JP H11511113 A5 JPH11511113 A5 JP H11511113A5 JP 1996531337 A JP1996531337 A JP 1996531337A JP 53133796 A JP53133796 A JP 53133796A JP H11511113 A5 JPH11511113 A5 JP H11511113A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9516943.9 | 1995-08-18 | ||
| GBGB9516943.9A GB9516943D0 (en) | 1995-08-18 | 1995-08-18 | Novel cyclopropylindoles and their secoprecursors,and their use as prodrugs |
| PCT/NZ1996/000083 WO1997007097A1 (en) | 1995-08-18 | 1996-08-19 | Cyclopropylindoles and their seco precursors, and their use as prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11511113A JPH11511113A (ja) | 1999-09-28 |
| JPH11511113A5 true JPH11511113A5 (2) | 2004-07-22 |
Family
ID=10779431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8531337A Withdrawn JPH11511113A (ja) | 1995-08-18 | 1996-08-19 | シクロプロピルインドール類およびそのセコ前駆体、ならびにプロドラッグとしてのこれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5985909A (2) |
| EP (1) | EP0850220A1 (2) |
| JP (1) | JPH11511113A (2) |
| AU (1) | AU707644B2 (2) |
| CA (1) | CA2229264A1 (2) |
| GB (1) | GB9516943D0 (2) |
| NZ (1) | NZ315410A (2) |
| WO (1) | WO1997007097A1 (2) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE310725T1 (de) * | 1996-09-12 | 2005-12-15 | Auckland Uniservices Ltd | Kondensierte n-acylindole als antitumormittel |
| US6130237A (en) * | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| GB9712370D0 (en) * | 1997-06-14 | 1997-08-13 | Aepact Ltd | Therapeutic systems |
| EP0887348A1 (en) * | 1997-06-25 | 1998-12-30 | Boehringer Mannheim Italia S.p.A. | Bis-Indole derivatives having antimetastatic activity, a process for their preparation and pharmaceutical compositions containing them |
| US6410584B1 (en) * | 1998-01-14 | 2002-06-25 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells with indole derivatives |
| GB9818730D0 (en) | 1998-08-27 | 1998-10-21 | Univ Portsmouth | Collections of compounds |
| ES2260570T3 (es) | 1998-08-27 | 2006-11-01 | Spirogen Limited | Pirrolobenziodiazepinas dimericas. |
| US6909006B1 (en) | 1999-08-27 | 2005-06-21 | Spirogen Limited | Cyclopropylindole derivatives |
| DE60335383D1 (de) | 2002-07-15 | 2011-01-27 | Univ Texas | Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen |
| GB0226593D0 (en) | 2002-11-14 | 2002-12-24 | Consultants Ltd | Compounds |
| ZA200507752B (en) * | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
| GB0321295D0 (en) | 2003-09-11 | 2003-10-15 | Spirogen Ltd | Synthesis of protected pyrrolobenzodiazepines |
| ZA200800314B (en) | 2005-06-29 | 2009-09-30 | Threshold Pharmaceuticals Inc | Phosphoramidate alkylator prodrugs |
| MX2008009956A (es) * | 2006-02-02 | 2008-12-12 | Syntarga Bv | Analogos de cc-1065 solubles en agua y sus conjugados. |
| GB0619325D0 (en) * | 2006-09-30 | 2006-11-08 | Univ Strathclyde | New compounds |
| US8552048B2 (en) * | 2006-12-26 | 2013-10-08 | Threshold Pharmaceuticals, Inc. | Phosphoramidate alkylator prodrugs for the treatment of cancer |
| US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
| US20090118031A1 (en) * | 2007-11-01 | 2009-05-07 | Qualizza Gregory K | Shaft Structure with Configurable Bending Profile |
| WO2009060198A1 (en) | 2007-11-09 | 2009-05-14 | Peregrine Pharmaceuticals, Inc. | Anti-vegf antibody compositions and methods |
| PE20091445A1 (es) * | 2007-12-03 | 2009-10-19 | Boehringer Ingelheim Int | Derivados de indolinona y procedimiento para su fabricacion |
| HUE035798T2 (en) | 2008-11-03 | 2018-05-28 | Syntarga Bv | CC-1065 analogues and conjugates |
| NO3056203T3 (2) | 2010-04-21 | 2018-05-12 | ||
| US9056874B2 (en) | 2012-05-04 | 2015-06-16 | Novartis Ag | Complement pathway modulators and uses thereof |
| US9475806B2 (en) | 2013-03-14 | 2016-10-25 | Novartis Ag | Complement factor B inhibitors and uses there of |
| EP3089963A1 (en) | 2013-10-30 | 2016-11-09 | Novartis AG | 2-benzyl-benzimidazole complement factor b inhibitors and uses thereof |
| TR201810856T4 (tr) | 2014-01-10 | 2018-08-27 | Synthon Biopharmaceuticals Bv | CYS'le bağlı antikor-ilaç konjugatlarını saflaştırmak için usul. |
| JP2024510435A (ja) | 2021-03-18 | 2024-03-07 | シージェン インコーポレイテッド | 生体活性化合物の内部移行複合体からの選択的薬物放出 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU617304B2 (en) * | 1986-12-19 | 1991-11-28 | Pharmacia & Upjohn Company | Novel cc-1065 analogs |
| GB8705477D0 (en) * | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
| AU648313B2 (en) * | 1990-04-25 | 1994-04-21 | Pharmacia & Upjohn Company | Novel CC-1065 analogs |
| JP4115514B2 (ja) * | 1991-10-23 | 2008-07-09 | キャンサー・リサーチ・キヤンペーン・テクノロジー・リミテツド | Ｃｂ １９５４およびその類似体を細胞障害性の形態に還元するための細菌のニトロリダクターゼ |
| NZ240785A (en) * | 1991-11-28 | 1995-08-28 | Cancer Res Campaign Tech | Substituted nitro aniline derivatives and medicaments |
| GB9314960D0 (en) * | 1992-07-23 | 1993-09-01 | Zeneca Ltd | Chemical compounds |
| GB9323008D0 (en) * | 1993-11-05 | 1994-01-05 | Connors Thomas | Improvements relating to cancer therapy |
-
1995
- 1995-08-18 GB GBGB9516943.9A patent/GB9516943D0/en active Pending
-
1996
- 1996-08-19 NZ NZ315410A patent/NZ315410A/xx unknown
- 1996-08-19 EP EP96927217A patent/EP0850220A1/en not_active Withdrawn
- 1996-08-19 AU AU67109/96A patent/AU707644B2/en not_active Ceased
- 1996-08-19 WO PCT/NZ1996/000083 patent/WO1997007097A1/en not_active Ceased
- 1996-08-19 US US09/011,883 patent/US5985909A/en not_active Expired - Fee Related
- 1996-08-19 CA CA002229264A patent/CA2229264A1/en not_active Abandoned
- 1996-08-19 JP JP8531337A patent/JPH11511113A/ja not_active Withdrawn