JPS5356669A - 4aaarylloctahydroo1hh22 pyridines - Google Patents

4aaarylloctahydroo1hh22 pyridines

Info

Publication number
JPS5356669A
JPS5356669A JP13211177A JP13211177A JPS5356669A JP S5356669 A JPS5356669 A JP S5356669A JP 13211177 A JP13211177 A JP 13211177A JP 13211177 A JP13211177 A JP 13211177A JP S5356669 A JPS5356669 A JP S5356669A
Authority
JP
Japan
Prior art keywords
pyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13211177A
Other languages
English (en)
Japanese (ja)
Inventor
Emu Tsuinmaaman Denisu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPS5356669A publication Critical patent/JPS5356669A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
JP13211177A 1976-11-02 1977-11-02 4aaarylloctahydroo1hh22 pyridines Pending JPS5356669A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73795876A 1976-11-02 1976-11-02

Publications (1)

Publication Number Publication Date
JPS5356669A true JPS5356669A (en) 1978-05-23

Family

ID=24965981

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13211177A Pending JPS5356669A (en) 1976-11-02 1977-11-02 4aaarylloctahydroo1hh22 pyridines

Country Status (26)

Country Link
JP (1) JPS5356669A (cs)
AR (1) AR223454A1 (cs)
AT (1) ATA782177A (cs)
AU (1) AU513679B2 (cs)
BE (1) BE860314A (cs)
CA (1) CA1100136A (cs)
CS (1) CS211380B2 (cs)
DD (1) DD133795A5 (cs)
DE (1) DE2748466A1 (cs)
DK (1) DK485277A (cs)
ES (3) ES463783A1 (cs)
FR (1) FR2369267A1 (cs)
GB (1) GB1590155A (cs)
GR (1) GR70053B (cs)
HU (1) HU176231B (cs)
IE (1) IE45901B1 (cs)
IL (1) IL53236A0 (cs)
NL (1) NL7712053A (cs)
NZ (1) NZ185539A (cs)
PH (1) PH12590A (cs)
PL (3) PL108466B1 (cs)
PT (1) PT67194B (cs)
RO (3) RO72900A (cs)
SE (3) SE7712218L (cs)
SU (3) SU812174A3 (cs)
ZA (1) ZA776497B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT68934A (en) * 1977-12-27 1979-01-01 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines
US4277608A (en) * 1979-06-21 1981-07-07 Eli Lilly And Company Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
US4236009A (en) * 1979-06-21 1980-11-25 Eli Lilly And Company Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
ZA9510829B (en) * 1994-12-23 1996-07-03 Smithkline Beecham Corp 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
US8598164B2 (en) 2010-05-06 2013-12-03 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
KR101923367B1 (ko) 2011-02-02 2018-12-04 버텍스 파마슈티칼스 인코포레이티드 이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드
WO2012112743A1 (en) 2011-02-18 2012-08-23 Vertex Pharmaceuticals Incorporated Chroman - spirocyclic piperidine amides as modulators of ion channels
US8828996B2 (en) 2011-03-14 2014-09-09 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels

Also Published As

Publication number Publication date
ZA776497B (en) 1979-06-27
PL109690B1 (en) 1980-06-30
RO72900A (ro) 1981-11-04
SE7712218L (sv) 1978-05-03
AR223454A1 (es) 1981-08-31
DD133795A5 (de) 1979-01-24
PT67194B (en) 1979-03-23
PH12590A (en) 1979-06-27
SE8103107L (sv) 1981-05-18
GR70053B (cs) 1982-07-26
CA1100136A (en) 1981-04-28
GB1590155A (en) 1981-05-28
PL108466B1 (en) 1980-04-30
FR2369267B1 (cs) 1980-05-16
IE45901B1 (en) 1982-12-29
SU913941A3 (en) 1982-03-15
ES463784A1 (es) 1978-06-16
NL7712053A (nl) 1978-05-05
ES472276A1 (es) 1979-10-01
SE8103106L (sv) 1981-05-18
ES463783A1 (es) 1979-07-16
PL201885A1 (pl) 1978-12-04
SU845777A3 (ru) 1981-07-07
SU812174A3 (ru) 1981-03-07
PT67194A (en) 1977-11-01
AU513679B2 (en) 1980-12-18
HU176231B (en) 1981-01-28
RO78300A (ro) 1982-04-12
IE45901L (en) 1978-05-02
CS211380B2 (en) 1982-02-26
DK485277A (da) 1978-05-03
IL53236A0 (en) 1977-12-30
PL108610B1 (en) 1980-04-30
ATA782177A (de) 1981-10-15
DE2748466A1 (de) 1978-05-03
FR2369267A1 (fr) 1978-05-26
AU3023577A (en) 1979-05-10
BE860314A (fr) 1978-04-28
NZ185539A (en) 1979-12-11
RO77935A (ro) 1981-12-25

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