JPS5483095A - Preparation of anti-thrombogenetic polyamide - Google Patents
Preparation of anti-thrombogenetic polyamideInfo
- Publication number
- JPS5483095A JPS5483095A JP15153277A JP15153277A JPS5483095A JP S5483095 A JPS5483095 A JP S5483095A JP 15153277 A JP15153277 A JP 15153277A JP 15153277 A JP15153277 A JP 15153277A JP S5483095 A JPS5483095 A JP S5483095A
- Authority
- JP
- Japan
- Prior art keywords
- polyamide
- thrombogenetic
- quaternarized
- aminated
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004952 Polyamide Substances 0.000 title abstract 6
- 229920002647 polyamide Polymers 0.000 title abstract 6
- 125000000129 anionic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- NLVXSWCKKBEXTG-UHFFFAOYSA-N vinylsulfonic acid Chemical compound OS(=O)(=O)C=C NLVXSWCKKBEXTG-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- External Artificial Organs (AREA)
- Materials For Medical Uses (AREA)
- Polyamides (AREA)
Abstract
PURPOSE: To prepare the title polyamide having excellent antithrombogenetic action, mechanical strength, and moldability, by reacting a quaternarized aminated polyamide with an anti-thrombogenetic compound having an anionic group.
CONSTITUTION: An aminated polyamide obtained by reacting a polyamide with an oligomer and/or polymer of ethylene imine of formula I or II (n≥2) in a solvent at -20 - +250°C for 10 min. -24 hours, is quaternarized by reacting with a quaternarization agent such as hydrogen halide, halogenated hydrocarbon, etc., at 0W90°C for 1W24 hours; and the quaternarized aminated polyamide is made to react with 0.01W10 wt.% aqueous solution of an anti-thrombogenetic compound having an anionic group, such as heparin, vinylsulfonic acid, etc., at 10W100°C.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP52151532A JPS6047287B2 (en) | 1977-12-15 | 1977-12-15 | Method for producing antithrombotic polyamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP52151532A JPS6047287B2 (en) | 1977-12-15 | 1977-12-15 | Method for producing antithrombotic polyamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5483095A true JPS5483095A (en) | 1979-07-02 |
| JPS6047287B2 JPS6047287B2 (en) | 1985-10-21 |
Family
ID=15520564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52151532A Expired JPS6047287B2 (en) | 1977-12-15 | 1977-12-15 | Method for producing antithrombotic polyamide |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6047287B2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58105759A (en) * | 1981-12-21 | 1983-06-23 | 東レ株式会社 | Anti-thromotic composition |
| JPS58173557A (en) * | 1982-04-05 | 1983-10-12 | 旭メディカル株式会社 | Header for blood treating apparatus and production thereof |
| WO2014168198A1 (en) * | 2013-04-12 | 2014-10-16 | 東レ株式会社 | Antithrombotic artificial blood vessel |
| US20180344906A1 (en) * | 2015-03-31 | 2018-12-06 | Toray Industries, Inc. | Antithrombotic metallic material |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3078389B1 (en) | 2013-11-28 | 2020-04-01 | Toray Industries, Inc. | Antithrombotic material |
| WO2015080176A1 (en) | 2013-11-28 | 2015-06-04 | 東レ株式会社 | Anti-thrombotic material |
| EP3106128B1 (en) | 2014-02-12 | 2020-12-02 | Toray Industries, Inc. | Artificial blood vessel |
| CN113330151A (en) | 2019-01-30 | 2021-08-31 | 东丽株式会社 | Medical base material for cardiovascular indwelling device |
-
1977
- 1977-12-15 JP JP52151532A patent/JPS6047287B2/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58105759A (en) * | 1981-12-21 | 1983-06-23 | 東レ株式会社 | Anti-thromotic composition |
| JPS58173557A (en) * | 1982-04-05 | 1983-10-12 | 旭メディカル株式会社 | Header for blood treating apparatus and production thereof |
| WO2014168198A1 (en) * | 2013-04-12 | 2014-10-16 | 東レ株式会社 | Antithrombotic artificial blood vessel |
| EP2985042A4 (en) * | 2013-04-12 | 2016-10-19 | Toray Industries | Antithrombotic artificial blood vessel |
| JPWO2014168198A1 (en) * | 2013-04-12 | 2017-02-16 | 東レ株式会社 | Artificial blood vessel with antithrombotic properties |
| US9662233B2 (en) | 2013-04-12 | 2017-05-30 | Toray Industries, Inc. | Antithrombotic artificial blood vessel |
| US20180344906A1 (en) * | 2015-03-31 | 2018-12-06 | Toray Industries, Inc. | Antithrombotic metallic material |
| US10709822B2 (en) * | 2015-03-31 | 2020-07-14 | Toray Industries, Inc. | Antithrombotic metallic material |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6047287B2 (en) | 1985-10-21 |
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