JPS5536445A - Naphthyloxybutyramide derivative - Google Patents
Naphthyloxybutyramide derivativeInfo
- Publication number
- JPS5536445A JPS5536445A JP11044478A JP11044478A JPS5536445A JP S5536445 A JPS5536445 A JP S5536445A JP 11044478 A JP11044478 A JP 11044478A JP 11044478 A JP11044478 A JP 11044478A JP S5536445 A JPS5536445 A JP S5536445A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- naphthyloxybutyramide
- derivative
- compound
- antiasthamitic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- JWAZRIHNYRIHIV-UHFFFAOYSA-N 2-naphthol Chemical compound C1=CC=CC2=CC(O)=CC=C21 JWAZRIHNYRIHIV-UHFFFAOYSA-N 0.000 abstract 1
- -1 N-Methyl-N-cyclohexyl-4-(β-naphthyloxy)butyramide Chemical compound 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:Naphthyloxybutyramide derivative of formula 1.
EXAMPLE: N-Methyl-N-cyclohexyl-4-(β-naphthyloxy)butyramide.
USE: Antithrombosis, anti-inflammatory, antiulcerative and antiasthamitic.
PREPARATION: β-Hydroxynaphthalene of formula 2 and a haloamide of formula 3 (X is Br, Cl, I) are subjected to dehydrohalogenation reaction to give the compound of formula 1. The compound of formula 2 is known, whereas the compound of formula 3 is novel, though partially known.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11044478A JPS5536445A (en) | 1978-09-07 | 1978-09-07 | Naphthyloxybutyramide derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11044478A JPS5536445A (en) | 1978-09-07 | 1978-09-07 | Naphthyloxybutyramide derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5536445A true JPS5536445A (en) | 1980-03-14 |
| JPS5761346B2 JPS5761346B2 (en) | 1982-12-23 |
Family
ID=14535867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11044478A Granted JPS5536445A (en) | 1978-09-07 | 1978-09-07 | Naphthyloxybutyramide derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5536445A (en) |
-
1978
- 1978-09-07 JP JP11044478A patent/JPS5536445A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5761346B2 (en) | 1982-12-23 |
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