JPS55501025A - - Google Patents

Info

Publication number: JPS55501025A
Authority: JP; Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP50190279A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-19

Filing date

1979-10-18

Publication date

1980-11-27

1979-10-18 Application filed filed Critical

1980-11-27 Publication of JPS55501025A publication Critical patent/JPS55501025A/ja

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polarising Elements (AREA)

JP50190279A 1978-10-19 1979-10-18 Pending JPS55501025A (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US95305678A	1978-10-19	1978-10-19

Publications (1)

Publication Number	Publication Date
JPS55501025A true JPS55501025A (cs)	1980-11-27

Family

ID=25493512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP50190279A Pending JPS55501025A (cs)	1978-10-19	1979-10-18

Country Status (16)

Country	Link
JP (1)	JPS55501025A (cs)
AU (1)	AU5189779A (cs)
BE (1)	BE879494A (cs)
CA (1)	CA1108132A (cs)
CS (1)	CS211364B2 (cs)
DK (1)	DK258280A (cs)
ES (1)	ES485154A1 (cs)
FI (1)	FI793235A7 (cs)
FR (1)	FR2439201A1 (cs)
GB (1)	GB2049680A (cs)
IL (1)	IL58489A0 (cs)
IT (1)	IT7969032A0 (cs)
NL (1)	NL7920126A (cs)
NO (1)	NO793297L (cs)
SE (1)	SE8004454L (cs)
WO (1)	WO1980000841A1 (cs)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795813A (en) *	1981-08-17	1989-01-03	The Florida Board Of Regents On Behalf Of The Florida State University	Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) *	1986-10-31	1997-09-16	The United States Of America As Represented By The Department Of Health And Human Services	Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) *	1988-09-13	1990-11-30	Sanofi Sa	Procede de preparation de derives de morphinane
ATE178329T1 (de) *	1989-10-16	1999-04-15	Us Health	Totale synthese von northebain-, normorphin-, noroxymorphon-enantiomeren und -derivaten via n- nor-zwischenverbindungen
KR20030048026A (ko)	2001-07-06	2003-06-18	펜웨스트 파머슈티칼즈 컴파니	옥시모르폰의 서방형 제제
US8329216B2 (en)	2001-07-06	2012-12-11	Endo Pharmaceuticals Inc.	Oxymorphone controlled release formulations
CN1610551A (zh)	2001-07-06	2005-04-27	恩德制药公司	用作止痛剂的6－羟基羟吗啡酮的肠胃外给药
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
MX2008010921A (es)	2006-03-02	2008-09-03	Mallinckrodt Inc	Procesos para preparar productos de morfinan-6-ona con bajos niveles de compuestos de cetona alfa, beta-insaturados.
KR101616246B1 (ko)	2008-01-25	2016-05-02	그뤼넨탈 게엠베하	약제학적 투여형
AU2009243681B2 (en)	2008-05-09	2013-12-19	Grunenthal Gmbh	Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
TWI473628B (zh)	2009-07-22	2015-02-21		用於對氧化敏感之類鴉片藥劑之抗破壞劑型
WO2011009602A1 (en)	2009-07-22	2011-01-27	Grünenthal GmbH	Hot-melt extruded controlled release dosage form
CA2808219C (en)	2010-09-02	2019-05-14	Gruenenthal Gmbh	Tamper resistant dosage form comprising inorganic salt
WO2012028318A1 (en)	2010-09-02	2012-03-08	Grünenthal GmbH	Tamper resistant dosage form comprising an anionic polymer
ES2648129T3 (es)	2011-07-29	2017-12-28	Grünenthal GmbH	Pastilla a prueba de manipulación que proporciona una liberación inmediata de un medicamento
AU2012289764B2 (en)	2011-07-29	2017-03-02	Grünenthal GmbH	Tamper-resistant tablet providing immediate drug release
US20130225697A1 (en)	2012-02-28	2013-08-29	Grunenthal Gmbh	Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
PL2838512T3 (pl)	2012-04-18	2018-12-31	Grünenthal GmbH	Farmaceutyczna postać dawkowania odporna na niewłaściwe użycie i odporna na uderzeniowe uwalnianie dawki
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
AU2014273227B2 (en)	2013-05-29	2019-08-15	Grunenthal Gmbh	Tamper-resistant dosage form containing one or more particles
JP6466417B2 (ja)	2013-05-29	2019-02-06	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	二峰性放出プロファイルを有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
JP6449871B2 (ja)	2013-07-12	2019-01-09	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	エチレン−酢酸ビニルポリマーを含有する改変防止剤形
EP3073994A1 (en)	2013-11-26	2016-10-05	Grünenthal GmbH	Preparation of a powdery pharmaceutical composition by means of cryo-milling
EP3142646A1 (en)	2014-05-12	2017-03-22	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
EA201692388A1 (ru)	2014-05-26	2017-05-31	Грюненталь Гмбх	Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы
BR112017021475A2 (pt)	2015-04-24	2018-07-10	Gruenenthal Gmbh	forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
WO2017042325A1 (en)	2015-09-10	2017-03-16	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
EP3252055B1 (en)	2016-05-31	2018-09-19	Alcaliber Investigacion Desarrollo e Innovacion SLU	Process for obtaining 3,14-diacetyloxymorphone from oripavine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3249616A (en) *		1966-05-03		Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) *	1955-08-03	1957-09-10	Lewenstein	Morphine derivative
US3775414A (en) *	1972-05-10	1973-11-27	Bristol Myers Co	Process for the preparation of 14-hydroxymorphinan derivatives

1979
- 1979-10-12 NO NO793297A patent/NO793297L/no unknown
- 1979-10-18 CA CA337,908A patent/CA1108132A/en not_active Expired
- 1979-10-18 FR FR7925895A patent/FR2439201A1/fr not_active Withdrawn
- 1979-10-18 WO PCT/US1979/000862 patent/WO1980000841A1/en not_active Ceased
- 1979-10-18 NL NL7920126A patent/NL7920126A/nl unknown
- 1979-10-18 JP JP50190279A patent/JPS55501025A/ja active Pending
- 1979-10-18 IL IL58489A patent/IL58489A0/xx unknown
- 1979-10-18 IT IT7969032A patent/IT7969032A0/it unknown
- 1979-10-18 AU AU51897/79A patent/AU5189779A/en not_active Abandoned
- 1979-10-18 ES ES485154A patent/ES485154A1/es not_active Expired
- 1979-10-18 GB GB8014422A patent/GB2049680A/en not_active Withdrawn
- 1979-10-18 FI FI793235A patent/FI793235A7/fi not_active Application Discontinuation
- 1979-10-18 BE BE0/197710A patent/BE879494A/fr unknown
- 1979-10-19 CS CS797115A patent/CS211364B2/cs unknown
1980
- 1980-06-16 SE SE8004454A patent/SE8004454L/xx not_active Application Discontinuation
- 1980-06-17 DK DK258280A patent/DK258280A/da unknown

Also Published As

Publication number	Publication date
NL7920126A (nl)	1980-08-29
IT7969032A0 (it)	1979-10-18
NO793297L (no)	1980-04-22
IL58489A0 (en)	1980-01-31
BE879494A (fr)	1980-02-15
GB2049680A (en)	1980-12-31
CA1108132A (en)	1981-09-01
CS211364B2 (en)	1982-02-26
ES485154A1 (es)	1980-06-16
AU5189779A (en)	1980-04-24
FR2439201A1 (fr)	1980-05-16
DK258280A (da)	1980-06-17
FI793235A7 (fi)	1981-01-01
WO1980000841A1 (en)	1980-05-01
SE8004454L (sv)	1980-06-16

Publication	Publication Date	Title
JPS55501025A (cs)	1980-11-27
AU3898778A (cs)	1978-09-28
AU73950S (cs)	1978-04-07
AU3892778A (cs)	1978-10-13
BG25973A1 (cs)	1979-01-12
BG26012A1 (cs)	1979-02-15
BE871570A (cs)	1979-02-15
BG25806A1 (cs)	1979-01-12
BG26006A1 (cs)	1979-02-15
BG25816A1 (cs)	1979-01-12
BG25818A1 (cs)	1979-01-12
BG25835A1 (cs)	1979-01-12
BG25836A1 (cs)	1979-01-12
BG25842A1 (cs)	1979-01-12
BG25843A1 (cs)	1979-01-12
BG25849A1 (cs)	1979-01-12
BG25857A1 (cs)	1979-01-12
BG25858A1 (cs)	1979-01-12
BG25871A1 (cs)	1979-01-12
BG25872A1 (cs)	1979-01-12
BG25874A1 (cs)	1979-01-12
BG25875A1 (cs)	1979-01-12
BG25879A1 (cs)	1979-01-12
BG25889A1 (cs)	1979-01-12
BG25897A1 (cs)	1979-01-12