JPS5555154A - Guanidinobenzoic acid derivative and its preparation - Google Patents

Guanidinobenzoic acid derivative and its preparation

Info

Publication number
JPS5555154A
JPS5555154A JP12867578A JP12867578A JPS5555154A JP S5555154 A JPS5555154 A JP S5555154A JP 12867578 A JP12867578 A JP 12867578A JP 12867578 A JP12867578 A JP 12867578A JP S5555154 A JPS5555154 A JP S5555154A
Authority
JP
Japan
Prior art keywords
formula
compound
preparation
guanidino
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12867578A
Other languages
Japanese (ja)
Other versions
JPS6049185B2 (en
Inventor
Setsuo Fujii
Takeshi Watanabe
Seiji Shioda
Itsuo Okumoto
Naohiro Kayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP12867578A priority Critical patent/JPS6049185B2/en
Publication of JPS5555154A publication Critical patent/JPS5555154A/en
Publication of JPS6049185B2 publication Critical patent/JPS6049185B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A guanidino-benzoic acid devivative of formula I: (Z is methylene, ethylene, or vinylene group; R is lower alkyl group), or its acid addition salt.
EXAMPLE: Methyl p-(p-guanidino-benzoyloxy)phenylacetate.
USE: Useful as a treating medicine for acute pancreatitis or as an antiplasmin agent for hemorrhagic diseases, having a strong inhibitory action on protease trypsin or plasmin.
PROCESS: An acid addition salt of a compound of formula II: (X is halogen) is reacted with a compound of formula III to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP12867578A 1978-10-20 1978-10-20 Guanidinobenzoic acid derivatives Expired JPS6049185B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12867578A JPS6049185B2 (en) 1978-10-20 1978-10-20 Guanidinobenzoic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12867578A JPS6049185B2 (en) 1978-10-20 1978-10-20 Guanidinobenzoic acid derivatives

Publications (2)

Publication Number Publication Date
JPS5555154A true JPS5555154A (en) 1980-04-22
JPS6049185B2 JPS6049185B2 (en) 1985-10-31

Family

ID=14990656

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12867578A Expired JPS6049185B2 (en) 1978-10-20 1978-10-20 Guanidinobenzoic acid derivatives

Country Status (1)

Country Link
JP (1) JPS6049185B2 (en)

Also Published As

Publication number Publication date
JPS6049185B2 (en) 1985-10-31

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