JPS5559113A - Method of making alkylated product of active methylene compound - Google Patents

Method of making alkylated product of active methylene compound

Info

Publication number
JPS5559113A
JPS5559113A JP13338078A JP13338078A JPS5559113A JP S5559113 A JPS5559113 A JP S5559113A JP 13338078 A JP13338078 A JP 13338078A JP 13338078 A JP13338078 A JP 13338078A JP S5559113 A JPS5559113 A JP S5559113A
Authority
JP
Japan
Prior art keywords
alkali hydroxide
fine particles
active methylene
methylene compound
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13338078A
Other languages
Japanese (ja)
Other versions
JPS6323177B2 (en
Inventor
Yoshiki Nakayama
Taro Inosawa
Yasushi Higuchi
Yutaka Oishi
Chihiro Yazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ihara Chemical Industry Co Ltd
Original Assignee
Ihara Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ihara Chemical Industry Co Ltd filed Critical Ihara Chemical Industry Co Ltd
Priority to JP13338078A priority Critical patent/JPS5559113A/en
Priority to US06/075,314 priority patent/US4307034A/en
Priority to DE19792937945 priority patent/DE2937945A1/en
Priority to NL7907113A priority patent/NL193189C/en
Priority to CH862079A priority patent/CH646615A5/en
Priority to CA000336278A priority patent/CA1142961A/en
Priority to FR797923788A priority patent/FR2437240B1/en
Priority to GB7933248A priority patent/GB2033362B/en
Priority to GB8131017A priority patent/GB2082563B/en
Priority to IT26018/79A priority patent/IT1165340B/en
Publication of JPS5559113A publication Critical patent/JPS5559113A/en
Priority to FR8017482A priority patent/FR2455577B1/en
Publication of JPS6323177B2 publication Critical patent/JPS6323177B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The reaction between an active hydrogen compound and an alkyl halide is effected in the presence of fine particles of alkali hydroxide to produce title compound useful as synthetic intermediate of medicine and agricultural chemical with no use of specific solvent in high yield and purity.
CONSTITUTION: In the presence of fine particles of alkali hydroxide with particle sizes of less than several hundred microns, preferably less than a hundred microns, an active hydrogen compound and an alkyl halide are made to react in a usual solvent as benzene or toluene preferably at 20W60°C for 0.5W1hr. The fine particles of alkali hydroxide is obtained by melting the alkali hydroxide in an inert solvent in the presence of a dispersant and then gradually cooling under vigorus stirring. The amount of the alkali used is 3W6 times the moles of the active methylene compound.
COPYRIGHT: (C)1980,JPO&Japio
JP13338078A 1978-09-26 1978-10-30 Method of making alkylated product of active methylene compound Granted JPS5559113A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP13338078A JPS5559113A (en) 1978-10-30 1978-10-30 Method of making alkylated product of active methylene compound
US06/075,314 US4307034A (en) 1978-09-26 1979-09-13 Inert organic solvent dispersion of alkali hydroxide and reaction using the same
DE19792937945 DE2937945A1 (en) 1978-09-26 1979-09-20 DISPERSION OF AN ALKALINE HYDROXIDE IN INERT ORGANIC SOLVENT AND IMPLEMENTATIONS USING THE SAME
CA000336278A CA1142961A (en) 1978-09-26 1979-09-25 Inert organic solvent dispersion of alkali hydroxide and reaction using the same
CH862079A CH646615A5 (en) 1978-09-26 1979-09-25 DISPERSION OF AN ALKALINE HYDROXIDE IN INERT ORGANIC SOLVENT AND IMPLEMENTATIONS USING THE SAME.
NL7907113A NL193189C (en) 1978-09-26 1979-09-25 Process for alkylating the methylene group of an organic compound with an active methylene group.
FR797923788A FR2437240B1 (en) 1978-09-26 1979-09-25 INVERTED ORGANIC SOLVENT DISPERSION OF AN ALKALINE HYDROXIDE AND REACTION USING THE SAME
GB7933248A GB2033362B (en) 1978-09-26 1979-09-26 Inert organic solvent dispersion of alkaline hydroxide andreaction using the same
GB8131017A GB2082563B (en) 1978-09-26 1979-09-26 Preparing inert organic solvent dispersion of alkaline hydroxide
IT26018/79A IT1165340B (en) 1978-09-26 1979-09-26 INERT ORGANIC SOLVENT DISPERSION OF ALKALINE HYDROXIDE AND REACTION USING THE SAME
FR8017482A FR2455577B1 (en) 1978-09-26 1980-08-07 IMPROVEMENT IN THE PROCESS FOR THE PREPARATION OF ORGANOALKYLATED METHYLENE COMPOUNDS BY ALKYLATION OF AN ACTIVE METHYLENE COMPOUND IN THE PRESENCE OF ALKALINE HYDROXIDE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13338078A JPS5559113A (en) 1978-10-30 1978-10-30 Method of making alkylated product of active methylene compound

Publications (2)

Publication Number Publication Date
JPS5559113A true JPS5559113A (en) 1980-05-02
JPS6323177B2 JPS6323177B2 (en) 1988-05-16

Family

ID=15103371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13338078A Granted JPS5559113A (en) 1978-09-26 1978-10-30 Method of making alkylated product of active methylene compound

Country Status (1)

Country Link
JP (1) JPS5559113A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5872551A (en) * 1981-10-07 1983-04-30 アメリカン・サイアナミド・カンパニ− Alkylation of phenylacetonitriles
JPS59118A (en) * 1982-06-25 1984-01-05 Nippon Telegr & Teleph Corp <Ntt> Machine for connecting multicore optical fiber by fusion
JP2010037298A (en) * 2008-08-07 2010-02-18 Toho Earthtech Inc Method for producing aliphatic diketone

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8829821D0 (en) * 1988-12-21 1989-02-15 Trico Folberth Ltd Pivot joint and method of producing such a pivot joint

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ORGANIC.REACTIONS *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5872551A (en) * 1981-10-07 1983-04-30 アメリカン・サイアナミド・カンパニ− Alkylation of phenylacetonitriles
JPS59118A (en) * 1982-06-25 1984-01-05 Nippon Telegr & Teleph Corp <Ntt> Machine for connecting multicore optical fiber by fusion
JP2010037298A (en) * 2008-08-07 2010-02-18 Toho Earthtech Inc Method for producing aliphatic diketone

Also Published As

Publication number Publication date
JPS6323177B2 (en) 1988-05-16

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