JPS5753653A - Liquid chromatography mass spectrometer - Google Patents

Liquid chromatography mass spectrometer

Info

Publication number
JPS5753653A
JPS5753653A JP55128760A JP12876080A JPS5753653A JP S5753653 A JPS5753653 A JP S5753653A JP 55128760 A JP55128760 A JP 55128760A JP 12876080 A JP12876080 A JP 12876080A JP S5753653 A JPS5753653 A JP S5753653A
Authority
JP
Japan
Prior art keywords
nozzle
lcg
impressed
electric potential
electroconductivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55128760A
Other languages
Japanese (ja)
Other versions
JPS6249932B2 (en
Inventor
Etsuo Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jeol Ltd
NTT Inc
Original Assignee
Jeol Ltd
Nihon Denshi KK
Nippon Telegraph and Telephone Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jeol Ltd, Nihon Denshi KK, Nippon Telegraph and Telephone Corp filed Critical Jeol Ltd
Priority to JP55128760A priority Critical patent/JPS5753653A/en
Publication of JPS5753653A publication Critical patent/JPS5753653A/en
Publication of JPS6249932B2 publication Critical patent/JPS6249932B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8429—Preparation of the fraction to be distributed adding modificating material
    • G01N2030/8441—Preparation of the fraction to be distributed adding modificating material to modify physical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/726—Nebulising, aerosol formation or ionisation by electrical or glow discharge

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

PURPOSE:To enable to analyze even low volatile sample without heating and to use a solvent with low electroconductivity, by setting up an electroconductive nozzle in liquid chromatographic apparatus (LCG) to mixing an electrolytic solution in a outlet flow of liquid between the nozzle and LCG. CONSTITUTION:A outlet flow from LCG4 is brought to a metallic nozzle 1 that pass through a flange of ion source. An electrolytic solution 8 (solution of NaH2PO4, HCl, NaOH, etc.) is brought to mixing section 5 through a line 7 to increase the electroconductivity in case of using an organic solvent with low electroconductivity for an eluate of LCG. An excess mixed solution is drained off through a dischange pipe 9 at a splitter section 6. A cathode 2 of a mass spectrometer (MS) is arranged gaginst the nozzle 1. Negative electric potential of about 2kV is impressed to the cathode 2 from an electric power source 13 and positive electric potential of about 8kV is impressed to the nozzle 1 from an electric power source 12, then a suitable electric potential is impressed on an ion source lens system 15. Thus ion is emitted from the top of the nozzle 1, and the out let flow from the LCG is ionized to analyse continuouslly and surely without heating the liquid, accordingly without plugging the piping and the nozzle.
JP55128760A 1980-09-17 1980-09-17 Liquid chromatography mass spectrometer Granted JPS5753653A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55128760A JPS5753653A (en) 1980-09-17 1980-09-17 Liquid chromatography mass spectrometer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55128760A JPS5753653A (en) 1980-09-17 1980-09-17 Liquid chromatography mass spectrometer

Publications (2)

Publication Number Publication Date
JPS5753653A true JPS5753653A (en) 1982-03-30
JPS6249932B2 JPS6249932B2 (en) 1987-10-22

Family

ID=14992780

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55128760A Granted JPS5753653A (en) 1980-09-17 1980-09-17 Liquid chromatography mass spectrometer

Country Status (1)

Country Link
JP (1) JPS5753653A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520430A (en) * 1983-01-28 1985-05-28 Union Carbide Corporation Lead attachment for tantalum anode bodies
JPH03105841A (en) * 1989-09-20 1991-05-02 Hitachi Ltd Mass spectrometry and its device
JPH07216565A (en) * 1994-02-02 1995-08-15 Internatl Business Mach Corp <Ibm> Device and method for attaching a dry film to a panel
WO2000018256A3 (en) * 1998-09-28 2000-10-19 Varian Inc Multiple liquid flow electrospray interface

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7604623B2 (en) 2005-08-30 2009-10-20 Kimberly-Clark Worldwide, Inc. Fluid applicator with a press activated pouch
US7565987B2 (en) 2005-08-31 2009-07-28 Kimberly-Clark Worldwide, Inc. Pull tab activated sealed packet
US7575384B2 (en) 2005-08-31 2009-08-18 Kimberly-Clark Worldwide, Inc. Fluid applicator with a pull tab activated pouch

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520430A (en) * 1983-01-28 1985-05-28 Union Carbide Corporation Lead attachment for tantalum anode bodies
JPH03105841A (en) * 1989-09-20 1991-05-02 Hitachi Ltd Mass spectrometry and its device
JPH07216565A (en) * 1994-02-02 1995-08-15 Internatl Business Mach Corp <Ibm> Device and method for attaching a dry film to a panel
WO2000018256A3 (en) * 1998-09-28 2000-10-19 Varian Inc Multiple liquid flow electrospray interface

Also Published As

Publication number Publication date
JPS6249932B2 (en) 1987-10-22

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