JPS5775979A - Acylated furanyl and thienylacrylic acids - Google Patents

Acylated furanyl and thienylacrylic acids

Info

Publication number: JPS5775979A
Authority: JP; Japan
Prior art keywords: acylated; furanyl; acids; thienylacrylic; amides
Prior art date: 1980-08-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP56131654A

Other languages

English (en)

Other versions

JPH0371427B2 (ja

Inventor

Ei Paakaa Rojiyaa

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Merrell Dow Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-08-27

Filing date

1981-08-24

Publication date

1982-05-12

1981-08-24 Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc

1982-05-12 Publication of JPS5775979A publication Critical patent/JPS5775979A/ja

1991-11-13 Publication of JPH0371427B2 publication Critical patent/JPH0371427B2/ja

Status Granted legal-status Critical Current

Links

239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
125000002541 furyl group Chemical group 0.000 title 1
150000001408 amides Chemical class 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
LXZFMKLKTRIZDJ-UHFFFAOYSA-N 2-(furan-2-yl)prop-2-enoic acid Chemical class OC(=O)C(=C)C1=CC=CO1 LXZFMKLKTRIZDJ-UHFFFAOYSA-N 0.000 abstract 1
-1 acylated thienyl acrylic acids Chemical class 0.000 abstract 1
230000000055 hyoplipidemic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Furan Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP56131654A 1980-08-27 1981-08-24 Acylated furanyl and thienylacrylic acids Granted JPS5775979A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US18191780A	1980-08-27	1980-08-27

Publications (2)

Publication Number	Publication Date
JPS5775979A true JPS5775979A (en)	1982-05-12
JPH0371427B2 JPH0371427B2 (ja)	1991-11-13

Family

ID=22666349

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP56131654A Granted JPS5775979A (en)	1980-08-27	1981-08-24	Acylated furanyl and thienylacrylic acids

Country Status (14)

Country	Link
EP (1)	EP0046595B1 (ja)
JP (1)	JPS5775979A (ja)
AT (1)	ATE10000T1 (ja)
AU (1)	AU546507B2 (ja)
CA (1)	CA1169431A (ja)
DE (1)	DE3166849D1 (ja)
DK (1)	DK164549C (ja)
ES (1)	ES8300328A1 (ja)
IE (1)	IE51573B1 (ja)
IL (1)	IL63632A (ja)
NO (1)	NO812904L (ja)
NZ (1)	NZ198145A (ja)
PH (1)	PH19421A (ja)
ZA (1)	ZA815959B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE602005027563D1 (de)	2004-05-28	2011-06-01	Expanscience Lab	Verwendung von furanalkylen zur kosmetischen behandlung von zellulitis
ES2340510T3 (es)	2004-05-28	2010-06-04	Laboratoires Expanscience	Uso de alquil-furanos para la preparacion de un medicamento destinado al tratamiento de la obesidad y para el tratamiento cosmetico del exceeso de peso.
FR2870742B1 (fr) *	2004-05-28	2008-03-14	Expanscience Laboratoires Sa	Utilisation d'alkyle furannes pour la preparation d'un medicament destine au traitement du diabete, de l'obesite et pour le traitement cosmetique de la cellulite et de la surcharge ponderale

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2632010A (en) *	1951-04-19	1953-03-17	Parke Davis & Co	N-alkyl thiopheneacrylamides
IL56517A0 (en) *	1978-02-02	1979-03-12	American Cyanamid Co	Novel 4-(cycloalkyl or cyclalkenyl substituted) amino, alkylamino or alkenylamino benzoic acids, salts and derivatives

1981
- 1981-08-21 IL IL63632A patent/IL63632A/xx unknown
- 1981-08-21 CA CA000384343A patent/CA1169431A/en not_active Expired
- 1981-08-24 JP JP56131654A patent/JPS5775979A/ja active Granted
- 1981-08-24 DK DK374281A patent/DK164549C/da not_active IP Right Cessation
- 1981-08-24 ES ES504915A patent/ES8300328A1/es not_active Expired
- 1981-08-24 NZ NZ198145A patent/NZ198145A/en unknown
- 1981-08-25 AU AU74608/81A patent/AU546507B2/en not_active Ceased
- 1981-08-25 DE DE8181106594T patent/DE3166849D1/de not_active Expired
- 1981-08-25 EP EP81106594A patent/EP0046595B1/en not_active Expired
- 1981-08-25 IE IE1950/81A patent/IE51573B1/en not_active IP Right Cessation
- 1981-08-25 AT AT81106594T patent/ATE10000T1/de not_active IP Right Cessation
- 1981-08-26 NO NO812904A patent/NO812904L/no unknown
- 1981-08-27 ZA ZA815959A patent/ZA815959B/xx unknown
- 1981-08-27 PH PH26111A patent/PH19421A/en unknown

Also Published As

Publication number	Publication date
IE51573B1 (en)	1987-01-21
JPH0371427B2 (ja)	1991-11-13
IL63632A (en)	1986-02-28
PH19421A (en)	1986-04-15
ES504915A0 (es)	1982-11-01
DK374281A (da)	1982-02-28
AU7460881A (en)	1982-03-04
ES8300328A1 (es)	1982-11-01
AU546507B2 (en)	1985-09-05
DK164549C (da)	1992-11-30
DE3166849D1 (en)	1984-11-29
DK164549B (da)	1992-07-13
ATE10000T1 (de)	1984-11-15
IL63632A0 (en)	1981-11-30
EP0046595B1 (en)	1984-10-24
EP0046595A1 (en)	1982-03-03
IE811950L (en)	1982-02-27
ZA815959B (en)	1982-09-29
CA1169431A (en)	1984-06-19
NZ198145A (en)	1984-04-27
NO812904L (no)	1982-03-01

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