JPS5798228A - Biphenyl derivative - Google Patents

Biphenyl derivative

Info

Publication number
JPS5798228A
JPS5798228A JP17505580A JP17505580A JPS5798228A JP S5798228 A JPS5798228 A JP S5798228A JP 17505580 A JP17505580 A JP 17505580A JP 17505580 A JP17505580 A JP 17505580A JP S5798228 A JPS5798228 A JP S5798228A
Authority
JP
Japan
Prior art keywords
compound
derivative
halogen
formula iii
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17505580A
Other languages
Japanese (ja)
Inventor
Kanji Noda
Akira Nakagawa
Satoru Miyata
Kazuyoshi Noguchi
Toshitaka Inoue
Masayoshi Tsuji
Tetsuo Aoki
Takenobu Mizoguchi
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP17505580A priority Critical patent/JPS5798228A/en
Publication of JPS5798228A publication Critical patent/JPS5798228A/en
Pending legal-status Critical Current

Links

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound of formulaI(R1 is H, aryl or lower alkyl; X and Y are H, CH3, halogen or CF3, except when both X and Y are H, and either one of X and Y is H, the other being 4'-bromo, 4'-chloro or 2'-fluoro).
EXAMPLE: 2-Methoxy-4'-fluorobiphenyl.
USE: An antimicrobial agent and an intermediate for a biphenylylacetic acid derivative having the analgesic anti-inflammatory and antipyretic actions.
PROCESS: The compound of formulaIis obtained by the following methods: (A) An aniline derivative of formula II is diazotized and coupled with anisole. (B) A halogenobenzene derivative of formula III (Z is halogen) is reacted with an o-alkoxyhalogenobenzene derivative in the presence of a metallic complex. (C) The compound of formula III is condensed with 2-chlorocyclohexanone and then converted into an aromatic compound.
COPYRIGHT: (C)1982,JPO&Japio
JP17505580A 1980-12-10 1980-12-10 Biphenyl derivative Pending JPS5798228A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17505580A JPS5798228A (en) 1980-12-10 1980-12-10 Biphenyl derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17505580A JPS5798228A (en) 1980-12-10 1980-12-10 Biphenyl derivative

Publications (1)

Publication Number Publication Date
JPS5798228A true JPS5798228A (en) 1982-06-18

Family

ID=15989437

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17505580A Pending JPS5798228A (en) 1980-12-10 1980-12-10 Biphenyl derivative

Country Status (1)

Country Link
JP (1) JPS5798228A (en)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100384193B1 (en) * 2000-11-14 2003-06-09 주식회사 에스엔테크 Preparation of 2,4-halogen substituted biphenyl derivatives
WO2004017920A3 (en) * 2002-08-23 2004-07-08 Univ Connecticut Novel biphenyl and biphenyl-like cannabinoids
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6939977B2 (en) 1998-05-04 2005-09-06 The University Of Connecticut Analgesic and immunomodulatory cannabinoids
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US6995187B1 (en) 1999-10-18 2006-02-07 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7057076B2 (en) 2001-07-13 2006-06-06 University Of Connecticut Bicyclic and tricyclic cannabinoids
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7173027B2 (en) 2001-01-29 2007-02-06 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7393842B2 (en) 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US7589220B2 (en) 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US8084467B2 (en) 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS491541A (en) * 1972-05-02 1974-01-08

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS491541A (en) * 1972-05-02 1974-01-08

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6939977B2 (en) 1998-05-04 2005-09-06 The University Of Connecticut Analgesic and immunomodulatory cannabinoids
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6995187B1 (en) 1999-10-18 2006-02-07 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US8084467B2 (en) 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
KR100384193B1 (en) * 2000-11-14 2003-06-09 주식회사 에스엔테크 Preparation of 2,4-halogen substituted biphenyl derivatives
US7173027B2 (en) 2001-01-29 2007-02-06 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
US7057076B2 (en) 2001-07-13 2006-06-06 University Of Connecticut Bicyclic and tricyclic cannabinoids
US7393842B2 (en) 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications
WO2004017920A3 (en) * 2002-08-23 2004-07-08 Univ Connecticut Novel biphenyl and biphenyl-like cannabinoids

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