JPS59222498A - 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤 - Google Patents

新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤

Info

Publication number
JPS59222498A
JPS59222498A JP58098631A JP9863183A JPS59222498A JP S59222498 A JPS59222498 A JP S59222498A JP 58098631 A JP58098631 A JP 58098631A JP 9863183 A JP9863183 A JP 9863183A JP S59222498 A JPS59222498 A JP S59222498A
Authority
JP
Japan
Prior art keywords
compound
formula
cis
platinum
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58098631A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0358358B2 (2
Inventor
Tetsushi Totani
戸谷　徹志
Katsutoshi Aono
青野　勝利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP58098631A priority Critical patent/JPS59222498A/ja
Priority to US06/606,961 priority patent/US4577038A/en
Priority to CA000454367A priority patent/CA1226295A/en
Priority to GB08412541A priority patent/GB2140804B/en
Priority to EP84106210A priority patent/EP0127884B1/en
Priority to DE8484106210T priority patent/DE3473762D1/de
Publication of JPS59222498A publication Critical patent/JPS59222498A/ja
Publication of JPH0358358B2 publication Critical patent/JPH0358358B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58098631A 1983-06-01 1983-06-01 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤 Granted JPS59222498A (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP58098631A JPS59222498A (ja) 1983-06-01 1983-06-01 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤
US06/606,961 US4577038A (en) 1983-06-01 1984-05-04 Glycolic acid type platinum complexes
CA000454367A CA1226295A (en) 1983-06-01 1984-05-15 Glycolic acid type platinum complexes
GB08412541A GB2140804B (en) 1983-06-01 1984-05-17 Glycolic acid type platinum complexes
EP84106210A EP0127884B1 (en) 1983-06-01 1984-05-30 Novel glycolic acid type platinum complexes
DE8484106210T DE3473762D1 (en) 1983-06-01 1984-05-30 Novel glycolic acid type platinum complexes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58098631A JPS59222498A (ja) 1983-06-01 1983-06-01 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤

Publications (2)

Publication Number Publication Date
JPS59222498A true JPS59222498A (ja) 1984-12-14
JPH0358358B2 JPH0358358B2 (2) 1991-09-05

Family

ID=14224854

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58098631A Granted JPS59222498A (ja) 1983-06-01 1983-06-01 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤

Country Status (6)

Country Link
US (1) US4577038A (2)
EP (1) EP0127884B1 (2)
JP (1) JPS59222498A (2)
CA (1) CA1226295A (2)
DE (1) DE3473762D1 (2)
GB (1) GB2140804B (2)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006169537A (ja) * 2004-12-17 2006-06-29 Wacker Chemie Ag 架橋性ポリオルガノシロキサン材料

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748254A (en) * 1984-01-23 1988-05-31 Institut Obschei I Neorganicheskoi Khimii Imeni N.S. Kurnakova Akademii Nauk SSR Mixed carboxylato platinum (II) complexes
JPS617283A (ja) * 1984-06-20 1986-01-13 Shionogi & Co Ltd 新規白金錯体および抗悪性腫瘍剤
DE3582961D1 (de) * 1984-06-27 1991-07-04 Johnson Matthey Plc Platinkoordinationsverbindungen.
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
JPH08176176A (ja) * 1994-12-26 1996-07-09 Ss Pharmaceut Co Ltd 白金錯体及びこれを含有する悪性腫瘍治療剤
WO2013083058A1 (zh) * 2011-12-07 2013-06-13 北京市丰硕维康技术开发有限责任公司 一类离去基团是含氨基或烷氨基的羟基酸衍生物的铂类化合物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (2) * 1972-06-08 1978-09-29 Research Corp
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
GB2025938B (en) * 1977-10-19 1982-11-03 Johnson Matthey Co Ltd (ii)-amine complexes
GB2006777B (en) * 1977-10-19 1982-10-27 Johnson Matthey Co Ltd Compositions containing platinum
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006169537A (ja) * 2004-12-17 2006-06-29 Wacker Chemie Ag 架橋性ポリオルガノシロキサン材料

Also Published As

Publication number Publication date
EP0127884A1 (en) 1984-12-12
JPH0358358B2 (2) 1991-09-05
GB8412541D0 (en) 1984-06-20
CA1226295A (en) 1987-09-01
EP0127884B1 (en) 1988-08-31
US4577038A (en) 1986-03-18
GB2140804B (en) 1986-10-29
GB2140804A (en) 1984-12-05
DE3473762D1 (en) 1988-10-06

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