JPS595114A - 抗動脈硬化症剤 - Google Patents

抗動脈硬化症剤

Info

Publication number
JPS595114A
JPS595114A JP58103003A JP10300383A JPS595114A JP S595114 A JPS595114 A JP S595114A JP 58103003 A JP58103003 A JP 58103003A JP 10300383 A JP10300383 A JP 10300383A JP S595114 A JPS595114 A JP S595114A
Authority
JP
Japan
Prior art keywords
dihydropyridine
atoms
alkyl
nitro
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58103003A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0553774B2 (it
Inventor
フリ−デル・ゾイタ−
フリ−ドリツヒ・ボツサ−ト
ホルスト・マイヤ−
エグバ−ト・ベヒンガ−
ホルスト・ベシヤゲン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS595114A publication Critical patent/JPS595114A/ja
Publication of JPH0553774B2 publication Critical patent/JPH0553774B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP58103003A 1982-06-15 1983-06-10 抗動脈硬化症剤 Granted JPS595114A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823222367 DE3222367A1 (de) 1982-06-15 1982-06-15 Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
DE3222367.6 1982-06-15

Publications (2)

Publication Number Publication Date
JPS595114A true JPS595114A (ja) 1984-01-12
JPH0553774B2 JPH0553774B2 (it) 1993-08-10

Family

ID=6166052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58103003A Granted JPS595114A (ja) 1982-06-15 1983-06-10 抗動脈硬化症剤

Country Status (9)

Country Link
JP (1) JPS595114A (it)
BE (1) BE897035A (it)
CA (1) CA1228549A (it)
DE (1) DE3222367A1 (it)
ES (1) ES8403456A1 (it)
FR (1) FR2528425B1 (it)
IL (1) IL68970A0 (it)
IT (1) IT1175920B (it)
ZA (1) ZA834344B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0627069B2 (ja) * 1984-11-12 1994-04-13 サンド・アクチエンゲゼルシヤフト １，４―ジヒドロピリジン誘導体の新規用途

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
GB8431119D0 (en) * 1984-12-10 1985-01-16 Fujisawa Pharmaceutical Co Anti-arteriosclerotic composition
GB2180532B (en) * 1985-09-17 1989-08-23 Inst Organicheskogo Sinteza Ak Alkoxy-and phenoxy-alkyl-esters of 2,6-dimethyl-4-(2-difluoromethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid
DE4222770A1 (de) * 1992-07-10 1994-01-13 Bayer Ag Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine
DE4328884A1 (de) * 1993-08-27 1995-03-02 Bayer Ag Verwendung von N-alkylierten 1,4-Dihydropyridincarbonsäureestern als Arzneimittel
DE60214428T2 (de) * 2001-12-20 2007-09-20 Bayer Healthcare Ag 1, 4-dihydro-1, 4-diphenylpyridin-derivate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750913A (en) * 1980-09-09 1982-03-25 Bayer Ag Nifedipin-containing solid medicine and manufacture

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2335466A1 (de) * 1973-07-12 1975-01-30 Bayer Ag Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2549568C3 (de) * 1975-11-05 1981-10-29 Bayer Ag, 5090 Leverkusen 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750913A (en) * 1980-09-09 1982-03-25 Bayer Ag Nifedipin-containing solid medicine and manufacture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0627069B2 (ja) * 1984-11-12 1994-04-13 サンド・アクチエンゲゼルシヤフト １，４―ジヒドロピリジン誘導体の新規用途

Also Published As

Publication number Publication date
CA1228549A (en) 1987-10-27
FR2528425A1 (fr) 1983-12-16
IT1175920B (it) 1987-08-12
IT8321465A0 (it) 1983-06-03
BE897035A (fr) 1983-12-13
DE3222367C2 (it) 1992-02-13
IL68970A0 (en) 1983-10-31
ES523244A0 (es) 1984-03-16
JPH0553774B2 (it) 1993-08-10
ES8403456A1 (es) 1984-03-16
ZA834344B (en) 1984-03-28
DE3222367A1 (de) 1983-12-15
FR2528425B1 (fr) 1987-02-06

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