JPS61200923A - 抗アレルギ−作用を有する物質とその製造方法 - Google Patents

抗アレルギ−作用を有する物質とその製造方法

Info

Publication number: JPS61200923A
Authority: JP; Japan
Prior art keywords: extract; lower alcohol; substance; antiallergic; residue
Prior art date: 1985-03-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP60043188A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0541608B2 (da

Inventor

Dotaro Fujimoto

藤本　導太郎

Hiroyuki Takahashi

宏幸高橋

Jun Morita

純森田

Koichi Tateishi

耕一建石

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Fujimoto Pharmaceutical Corp

Original Assignee

Fujimoto Pharmaceutical Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-04

Filing date

1985-03-04

Publication date

1986-09-05

1985-03-04 Application filed by Fujimoto Pharmaceutical Corp filed Critical Fujimoto Pharmaceutical Corp

1985-03-04 Priority to JP60043188A priority Critical patent/JPS61200923A/ja

1986-09-05 Publication of JPS61200923A publication Critical patent/JPS61200923A/ja

1993-06-24 Publication of JPH0541608B2 publication Critical patent/JPH0541608B2/ja

Status Granted legal-status Critical Current

Links

239000000126 substance Substances 0.000 title claims abstract description 13
230000003266 anti-allergic effect Effects 0.000 title claims abstract description 9
238000004519 manufacturing process Methods 0.000 title claims description 5
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims abstract description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
239000000284 extract Substances 0.000 claims abstract description 13
239000002244 precipitate Substances 0.000 claims abstract description 10
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 9
238000000502 dialysis Methods 0.000 claims abstract description 9
238000002523 gelfiltration Methods 0.000 claims abstract description 7
239000007864 aqueous solution Substances 0.000 claims abstract description 5
238000005342 ion exchange Methods 0.000 claims abstract description 4
235000001674 Agaricus brunnescens Nutrition 0.000 claims description 9
238000000746 purification Methods 0.000 claims description 5
238000007796 conventional method Methods 0.000 claims description 3
230000000704 physical effect Effects 0.000 claims description 2
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract description 12
238000000034 method Methods 0.000 abstract description 7
230000000694 effects Effects 0.000 abstract description 5
239000012528 membrane Substances 0.000 abstract description 5
150000001875 compounds Chemical class 0.000 abstract description 4
241000001493 Sarcodon aspratus Species 0.000 abstract description 3
239000002994 raw material Substances 0.000 abstract description 3
229920002678 cellulose Polymers 0.000 abstract description 2
239000001913 cellulose Substances 0.000 abstract description 2
150000002772 monosaccharides Chemical class 0.000 abstract description 2
238000001556 precipitation Methods 0.000 abstract description 2
235000013399 edible fruits Nutrition 0.000 abstract 2
239000000043 antiallergic agent Substances 0.000 abstract 1
239000000047 product Substances 0.000 abstract 1
239000000706 filtrate Substances 0.000 description 12
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
239000000843 powder Substances 0.000 description 6
239000011347 resin Substances 0.000 description 6
229920005989 resin Polymers 0.000 description 6
239000000243 solution Substances 0.000 description 6
239000000427 antigen Substances 0.000 description 5
102000036639 antigens Human genes 0.000 description 5
108091007433 antigens Proteins 0.000 description 5
238000000605 extraction Methods 0.000 description 5
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 4
239000003957 anion exchange resin Substances 0.000 description 4
239000003729 cation exchange resin Substances 0.000 description 4
241000700199 Cavia porcellus Species 0.000 description 3
239000003814 drug Substances 0.000 description 3
229940079593 drug Drugs 0.000 description 3
238000002474 experimental method Methods 0.000 description 3
239000000463 material Substances 0.000 description 3
239000000203 mixture Substances 0.000 description 3
229940092253 ovalbumin Drugs 0.000 description 3
239000011780 sodium chloride Substances 0.000 description 3
SPCKHVPPRJWQRZ-UHFFFAOYSA-N 2-benzhydryloxy-n,n-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 SPCKHVPPRJWQRZ-UHFFFAOYSA-N 0.000 description 2
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
108010058846 Ovalbumin Proteins 0.000 description 2
206010040914 Skin reaction Diseases 0.000 description 2
238000000862 absorption spectrum Methods 0.000 description 2
239000003463 adsorbent Substances 0.000 description 2
150000001450 anions Chemical class 0.000 description 2
229960000520 diphenhydramine Drugs 0.000 description 2
238000001914 filtration Methods 0.000 description 2
239000012530 fluid Substances 0.000 description 2
239000003456 ion exchange resin Substances 0.000 description 2
229920003303 ion-exchange polymer Polymers 0.000 description 2
230000000144 pharmacologic effect Effects 0.000 description 2
239000000049 pigment Substances 0.000 description 2
238000010992 reflux Methods 0.000 description 2
230000035483 skin reaction Effects 0.000 description 2
231100000430 skin reaction Toxicity 0.000 description 2
238000003756 stirring Methods 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
206010011655 Cushingoid Diseases 0.000 description 1
201000005505 Measles Diseases 0.000 description 1
206010030113 Oedema Diseases 0.000 description 1
239000012506 Sephacryl® Substances 0.000 description 1
206010041349 Somnolence Diseases 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
230000001919 adrenal effect Effects 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
229940125715 antihistaminic agent Drugs 0.000 description 1
239000000739 antihistaminic agent Substances 0.000 description 1
235000012745 brilliant blue FCF Nutrition 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
238000004587 chromatography analysis Methods 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
238000012258 culturing Methods 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000000385 dialysis solution Substances 0.000 description 1
238000001035 drying Methods 0.000 description 1
238000010828 elution Methods 0.000 description 1
239000003925 fat Substances 0.000 description 1
238000011597 hartley guinea pig Methods 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
231100000957 no side effect Toxicity 0.000 description 1
OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
239000002504 physiological saline solution Substances 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
150000003431 steroids Chemical class 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
210000003462 vein Anatomy 0.000 description 1
230000002747 voluntary effect Effects 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Landscapes

Medicines Containing Plant Substances (AREA)

JP60043188A 1985-03-04 1985-03-04 抗アレルギ−作用を有する物質とその製造方法 Granted JPS61200923A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP60043188A JPS61200923A (ja)	1985-03-04	1985-03-04	抗アレルギ−作用を有する物質とその製造方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP60043188A JPS61200923A (ja)	1985-03-04	1985-03-04	抗アレルギ−作用を有する物質とその製造方法

Publications (2)

Publication Number	Publication Date
JPS61200923A true JPS61200923A (ja)	1986-09-05
JPH0541608B2 JPH0541608B2 (da)	1993-06-24

Family

ID=12656941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP60043188A Granted JPS61200923A (ja)	1985-03-04	1985-03-04	抗アレルギ−作用を有する物質とその製造方法

Country Status (1)

Country	Link
JP (1)	JPS61200923A (da)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63297400A (ja) *	1987-05-29	1988-12-05	Fujimoto Seiyaku Kk	抗アレルギ−作用を有する物質とその製造方法
JPH0554665U (ja) *	1991-03-01	1993-07-23	テムコ株式会社	自己制御水道凍結防止器
JP2005075740A (ja) *	2003-08-28	2005-03-24	Hajime Otani	免疫賦活化組成物、並びにそれが含まれた医薬品、動物薬、食品、飼料及び化粧品

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001151689A (ja) *	1999-11-29	2001-06-05	Naris Cosmetics Co Ltd	皮膚外用剤

1985
- 1985-03-04 JP JP60043188A patent/JPS61200923A/ja active Granted

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63297400A (ja) *	1987-05-29	1988-12-05	Fujimoto Seiyaku Kk	抗アレルギ−作用を有する物質とその製造方法
JPH0554665U (ja) *	1991-03-01	1993-07-23	テムコ株式会社	自己制御水道凍結防止器
JP2005075740A (ja) *	2003-08-28	2005-03-24	Hajime Otani	免疫賦活化組成物、並びにそれが含まれた医薬品、動物薬、食品、飼料及び化粧品

Also Published As

Publication number	Publication date
JPH0541608B2 (da)	1993-06-24

Publication	Publication Date	Title
US4409144A (en)	1983-10-11	Xeronine, a new alkaloid, useful in medical, food and industrial fields
EP0030444B1 (en)	1985-01-30	A process for preparing substances having interferon inducing activity
DE69431024T2 (de)	2003-01-30	Neues physiologisch aktives Mittel
US5057324A (en)	1991-10-15	Kallikrein inhibitor substance, a process for preparation and pharmaceutical compositions thereof
CN106265754A (zh)	2017-01-04	一种从美洲大蠊中连环提取得到两种有效成分的方法
JPS6312846B2 (da)	1988-03-23
CA1083137A (en)	1980-08-05	Isolation of physiologically active substances
JPS61200923A (ja)	1986-09-05	抗アレルギ−作用を有する物質とその製造方法
CA2430113A1 (en)	2002-05-30	Process for preparing aqueous extracts of plants and extracts so obtained
HU203043B (en)	1991-05-28	Process for producing pharmaceutical compositions against tumour and ulcer containing euphorbia hirta l. it's parts or extract
KR0168485B1 (ko)	1998-12-01	산성다당체를 다량 함유하는 홍삼엑기스 제조방법
CN119264286A (zh)	2025-01-07	一种石斛多糖及其制备方法和应用
CN108997509B (zh)	2021-01-01	一种分心木多糖、分心木多糖的制备方法及用途
DE19600301C2 (de)	1999-12-09	Durch Cyclooligomerisierung des einfachen Kohlensuboxids C¶3¶O¶2¶ aufgebaute makrocyclische Verbindungen, Verfahren zu deren Herstellung und Gewinnung sowie deren Verwendung
CH634854A5 (de)	1983-02-28	Verfahren zur herstellung organopeptidhaltiger substanzen mit insulinaehnlicher wirksamkeit aus blut oder blutbestandteilen.
GB2101888A (en)	1983-01-26	Vegetable/animal extracts
JP4480204B2 (ja)	2010-06-16	カワリハラタケの抗腫瘍性画分
KR0124969B1 (ko)	1997-11-28	백삼박으로부터 산성 다당체의 제조방법
DE1293705B (de)	1969-04-30	Verfahren zur Gewinnung eines elastolytisch wirksamen Bauchspeicheldruesen-Praeparates
US3172813A (en)	1965-03-09	Process for preparation of kidney extracts
AU2021100051A4 (en)	2021-03-25	Antitumor formula and extraction method thereof
US3919186A (en)	1975-11-11	Method of recovering cytobiotic globulin from skin tissue
JPS6372629A (ja)	1988-04-02	霊芝から生理活性エキスを製造する方法
JPS6338325B2 (da)	1988-07-29
JPS56102787A (en)	1981-08-17	Preparation of human placenta superoxide dismutase

JPS61200923A - 抗アレルギ−作用を有する物質とその製造方法 - Google Patents

Info

Links

Landscapes

Priority Applications (1)

Applications Claiming Priority (1)

Publications (2)

Family

ID=12656941

Family Applications (1)

Country Status (1)

Cited By (3)

Families Citing this family (1)

Cited By (3)

Also Published As

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