JPS6121453B2 - - Google Patents

Info

Publication number
JPS6121453B2
JPS6121453B2 JP53155873A JP15587378A JPS6121453B2 JP S6121453 B2 JPS6121453 B2 JP S6121453B2 JP 53155873 A JP53155873 A JP 53155873A JP 15587378 A JP15587378 A JP 15587378A JP S6121453 B2 JPS6121453 B2 JP S6121453B2
Authority
JP
Japan
Prior art keywords
composition
compounds
anthelmintic
milbemycin
feed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53155873A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5489041A (en
Inventor
Pataa Maauingu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5489041A publication Critical patent/JPS5489041A/ja
Publication of JPS6121453B2 publication Critical patent/JPS6121453B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
JP15587378A 1977-12-19 1978-12-19 Myrbemicine compound as vermicide Granted JPS5489041A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/861,808 US4144352A (en) 1977-12-19 1977-12-19 Milbemycin compounds as anthelmintic agents

Publications (2)

Publication Number Publication Date
JPS5489041A JPS5489041A (en) 1979-07-14
JPS6121453B2 true JPS6121453B2 (2) 1986-05-27

Family

ID=25336823

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15587378A Granted JPS5489041A (en) 1977-12-19 1978-12-19 Myrbemicine compound as vermicide

Country Status (7)

Country Link
US (1) US4144352A (2)
EP (1) EP0002916B1 (2)
JP (1) JPS5489041A (2)
AU (1) AU526160B2 (2)
DE (1) DE2861426D1 (2)
NZ (1) NZ189103A (2)
ZA (1) ZA787082B (2)

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US4686297A (en) * 1985-07-22 1987-08-11 The Upjohn Company Anthelmintic spiroketals useful for killing parasitic worms
US4820758A (en) * 1985-07-22 1989-04-11 The Upjohn Company Novel [5.5]-spiroketals
US4812582A (en) * 1985-07-22 1989-03-14 The Upjohn Company Process for preparing aldol intermediates
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ES2086022T3 (es) * 1991-07-23 1996-06-16 American Cyanamid Co Composiciones estables para administracion parenteral y su uso.
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ES2359973T3 (es) * 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
US7671034B2 (en) 2003-12-19 2010-03-02 Merial Limited Stabilized formulation of ivermectin feed premix with an extended shelf life
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
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FR2906466B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des milbemycines pour le traitement de desordres dermatologiques chez l'homme
CN100467473C (zh) * 2007-01-17 2009-03-11 东北农业大学 用冰城链霉菌制备化合物的方法
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WO2009070687A1 (en) 2007-11-26 2009-06-04 Merial Limited Solvent systems for pour-on formulations for combating parasites
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MY155497A (en) 2008-11-19 2015-10-30 Merial Inc Compositions comprising an aryl pyrazole and/or a formamidine, methods and use thereof
JP5595412B2 (ja) 2008-12-04 2014-09-24 メリアル リミテッド 二量体アベルメクチン及びミルベマイシン誘導体
CN102712583B (zh) 2009-12-04 2015-04-08 梅里亚有限公司 农药用双-有机硫化合物
RS54772B1 (sr) 2009-12-17 2016-10-31 Merial Sas Antiparazitska jedinjenja dihidroazola i kompozicije koje ih sadrže
BR112012014933B1 (pt) 2009-12-17 2020-10-27 Merial, Inc. composições que compreendem compostos lactonas macrocíclicas e spirodioxepinoindóis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2629772B1 (en) 2010-10-20 2016-05-18 Galderma S.A. Ivermectin for use in the treatment of hemorrhoids
US8901090B2 (en) 2010-10-20 2014-12-02 Galderma S.A. Method of treating otitis externa using macrocyclic lactone compound
US8822528B2 (en) 2010-11-16 2014-09-02 Merial Limited Monensin derivatives for the treatment and prevention of protozoal infections
WO2012150543A1 (en) 2011-05-02 2012-11-08 Universite De Geneve Macrocyclic lactones and use thereof
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
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RS58417B1 (sr) 2011-09-12 2019-04-30 Merial Inc Paraziticidne kompozicije koje sadrže izoksazolinsko aktivno sredstvo, postupci i upotrebe povezane sa njima
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
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BR112014013371B1 (pt) 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
EP3216448B8 (en) 2012-02-06 2019-06-05 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
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BR122015032741B1 (pt) 2012-04-20 2019-11-26 Merial Ltd composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
EP2950795B1 (en) 2013-01-31 2018-04-25 Merial, Inc. Method for treating and curing leishmaniosis using fexinindazole
US10307405B2 (en) 2013-04-12 2019-06-04 Zoetis Services Llc Stable veterinary combination formulations of macrocyclic lactones and imidazothiazoles
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
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ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
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US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
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LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
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BR112020003217A2 (pt) 2017-08-14 2020-10-06 Boehringer Ingelheim Animal Health USA Inc. compostos pesticidas e parasiticidas de pirazolisoxazolina
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EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
AU2019301510B2 (en) 2018-07-09 2024-06-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelminthic heterocyclic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
AU2020231319A1 (en) 2019-03-01 2021-10-21 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
BR112022000982A2 (pt) 2019-07-22 2022-03-08 Intervet Int Bv Forma de dosagem veterinária mastigável macia
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances

Also Published As

Publication number Publication date
US4144352A (en) 1979-03-13
AU526160B2 (en) 1982-12-23
AU4230978A (en) 1979-06-28
EP0002916B1 (en) 1981-12-02
EP0002916A2 (en) 1979-07-11
ZA787082B (en) 1980-08-27
JPS5489041A (en) 1979-07-14
DE2861426D1 (en) 1982-01-28
NZ189103A (en) 1984-10-19
EP0002916A3 (en) 1979-07-25

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