JPS6121526B2 - - Google Patents

Info

Publication number
JPS6121526B2
JPS6121526B2 JP55137124A JP13712480A JPS6121526B2 JP S6121526 B2 JPS6121526 B2 JP S6121526B2 JP 55137124 A JP55137124 A JP 55137124A JP 13712480 A JP13712480 A JP 13712480A JP S6121526 B2 JPS6121526 B2 JP S6121526B2
Authority
JP
Japan
Prior art keywords
ascorbate
sodium
granules
weight
tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55137124A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5759803A (en
Inventor
Nobuyuki Kitamori
Keiji Henmi
Masaya Maeno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP55137124A priority Critical patent/JPS5759803A/ja
Priority to US06/201,965 priority patent/US4372968A/en
Priority to CA000363755A priority patent/CA1142432A/en
Priority to AU64123/80A priority patent/AU523837B2/en
Priority to AR286790A priority patent/AR229033A1/es
Priority to ZA816504A priority patent/ZA816504B/xx
Priority to DE8181304461T priority patent/DE3175304D1/de
Priority to EP81304461A priority patent/EP0049143B1/en
Priority to ES505823A priority patent/ES505823A0/es
Priority to MX819682U priority patent/MX6965E/es
Priority to DK430481A priority patent/DK164536C/da
Priority to NZ198493A priority patent/NZ198493A/en
Publication of JPS5759803A publication Critical patent/JPS5759803A/ja
Publication of JPS6121526B2 publication Critical patent/JPS6121526B2/ja
Priority to MY653/87A priority patent/MY8700653A/xx
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP55137124A 1980-09-30 1980-09-30 Granule of l-sodium ascorbate, its preparation, and tablet comprising it Granted JPS5759803A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP55137124A JPS5759803A (en) 1980-09-30 1980-09-30 Granule of l-sodium ascorbate, its preparation, and tablet comprising it
US06/201,965 US4372968A (en) 1980-09-30 1980-10-29 Granules of sodium ascorbate and the production thereof
CA000363755A CA1142432A (en) 1980-09-30 1980-10-31 Granules of sodium ascorbate and the production thereof
AU64123/80A AU523837B2 (en) 1980-09-30 1980-11-06 L-ascorbate granules
AR286790A AR229033A1 (es) 1980-09-30 1981-09-17 Procedimiento para obtener granulos y tabletas de ascorbato de sodio
ZA816504A ZA816504B (en) 1980-09-30 1981-09-18 Granules of sodium ascorbate and the production thereof
EP81304461A EP0049143B1 (en) 1980-09-30 1981-09-28 Granules of sodium ascorbate and the production thereof
DE8181304461T DE3175304D1 (en) 1980-09-30 1981-09-28 Granules of sodium ascorbate and the production thereof
ES505823A ES505823A0 (es) 1980-09-30 1981-09-28 Un metodo para producir granulos de l-ascorbato sodico
MX819682U MX6965E (es) 1980-09-30 1981-09-29 Procedimiento para elaborar granulos de l-ascorbato de sodio
DK430481A DK164536C (da) 1980-09-30 1981-09-29 Fremgangsmaade til fremstilling af tabletter indeholdende natrium-l-askorbat
NZ198493A NZ198493A (en) 1980-09-30 1981-09-29 Sodium l-ascorbate granules and tablets,and processes for their production
MY653/87A MY8700653A (en) 1980-09-30 1987-12-30 Granules of sodium ascorbate and the production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55137124A JPS5759803A (en) 1980-09-30 1980-09-30 Granule of l-sodium ascorbate, its preparation, and tablet comprising it

Publications (2)

Publication Number Publication Date
JPS5759803A JPS5759803A (en) 1982-04-10
JPS6121526B2 true JPS6121526B2 (2) 1986-05-27

Family

ID=15191372

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55137124A Granted JPS5759803A (en) 1980-09-30 1980-09-30 Granule of l-sodium ascorbate, its preparation, and tablet comprising it

Country Status (13)

Country Link
US (1) US4372968A (2)
EP (1) EP0049143B1 (2)
JP (1) JPS5759803A (2)
AR (1) AR229033A1 (2)
AU (1) AU523837B2 (2)
CA (1) CA1142432A (2)
DE (1) DE3175304D1 (2)
DK (1) DK164536C (2)
ES (1) ES505823A0 (2)
MX (1) MX6965E (2)
MY (1) MY8700653A (2)
NZ (1) NZ198493A (2)
ZA (1) ZA816504B (2)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998009624A1 (fr) * 1996-09-05 1998-03-12 Takeda Chemical Industries, Ltd. Composition vitaminique hydrosoluble fournissant de remarquables comprimes et technique de production

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495177A (en) * 1983-01-17 1985-01-22 Shaklee Corporation Gel tableting agent
US4533674A (en) * 1983-10-24 1985-08-06 Basf Wyandotte Corporation Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid
JPH0753663B2 (ja) * 1984-10-09 1995-06-07 武田薬品工業株式会社 チアミン塩の顆粒，その製造法および錠剤
JPS61145111A (ja) * 1984-12-20 1986-07-02 Lion Corp アセトアミノフェン含有錠剤の製造方法
DE3447422A1 (de) * 1984-12-24 1986-06-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von ascorbinsaeure-granulat
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
AU587863B2 (en) * 1985-10-07 1989-08-31 Basf Aktiengesellschaft Vitamin-containing granules and production thereof
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
AU1193092A (en) * 1992-01-10 1993-08-03 Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki Granulated pharmaceutical composition and method of obtaining it
DE19733094A1 (de) * 1997-07-31 1999-02-04 Merck Patent Gmbh Formulierung auf der Basis von Ascorbinsäure mit verbesserter Farbstabilität
US20030138485A1 (en) * 1998-01-14 2003-07-24 Daiichi Pharmaceutical Co., Ltd. Disintegrant
ATE250415T1 (de) * 1999-12-22 2003-10-15 Hoffmann La Roche Arzneizusammensetzung enthaltend ascorbinsäure und pektin
US6786949B2 (en) * 2001-03-20 2004-09-07 Startec Iron, Llc Method and apparatus for using a pre-jel for producing self-reducing agglomerates
CN1325049C (zh) * 2001-07-30 2007-07-11 Dsmip资产有限公司 含有表没食子儿茶素没食子酸酯的组合物
US20050008692A1 (en) * 2001-09-03 2005-01-13 Chyi-Cheng Chen Compositions comprising pectin and ascorbic acid
DE602004020187D1 (de) * 2003-02-20 2009-05-07 Constant Res & Dev Ltd Prozess zur Herstellung einer Dexamethason enthaltenden Formulierung zur oralen Anwendung
CN100431515C (zh) * 2005-05-24 2008-11-12 浙江大学 稳定微粒化药物添加剂的制备方法
CN104605224A (zh) * 2014-12-11 2015-05-13 张莘蔓 一种原菠萝味维生素c钠口含片及其制备工艺
CN106420643B (zh) * 2016-10-28 2019-08-16 广西圣保堂健康产业股份有限公司 一种含维生素c钠的咀嚼片及其制备方法
JP2023083990A (ja) * 2021-12-06 2023-06-16 東和薬品株式会社 シタグリプチンリン酸塩無水物経口製剤の安定化方法および用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453368A (en) * 1966-01-13 1969-07-01 Hoffmann La Roche Smaller high potency compressed tablets of ascorbic acid
US3493659A (en) * 1967-10-23 1970-02-03 Hoffmann La Roche Compositions and process for the production thereof
GB1443923A (en) * 1972-05-02 1976-07-28 Shepard M Sustained release compositions
NL184308C (nl) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd Werkwijze voor het bereiden van l-ascorbienzuurgranules.
JPS58403B2 (ja) * 1975-07-24 1983-01-06 武田薬品工業株式会社 Ｌ− アスコルビンサンセイザイノ セイゾウホウ

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998009624A1 (fr) * 1996-09-05 1998-03-12 Takeda Chemical Industries, Ltd. Composition vitaminique hydrosoluble fournissant de remarquables comprimes et technique de production
JPH1077224A (ja) * 1996-09-05 1998-03-24 Takeda Chem Ind Ltd 錠剤特性の優れた水溶性ビタミン組成物およびその製造法

Also Published As

Publication number Publication date
DK164536C (da) 1992-11-30
EP0049143B1 (en) 1986-09-10
CA1142432A (en) 1983-03-08
US4372968A (en) 1983-02-08
EP0049143A3 (en) 1982-12-29
AU6412380A (en) 1982-04-08
MY8700653A (en) 1987-12-31
NZ198493A (en) 1984-02-03
DK430481A (da) 1982-03-31
EP0049143A2 (en) 1982-04-07
ES8301628A1 (es) 1983-01-01
ZA816504B (en) 1982-12-29
ES505823A0 (es) 1983-01-01
AR229033A1 (es) 1983-05-31
JPS5759803A (en) 1982-04-10
AU523837B2 (en) 1982-08-19
DE3175304D1 (en) 1986-10-16
DK164536B (da) 1992-07-13
MX6965E (es) 1987-01-08

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