JPS6229559A - 新規脂環式ケトアミン、その製法及びこれを含有する心臓機能改良剤 - Google Patents

新規脂環式ケトアミン、その製法及びこれを含有する心臓機能改良剤

Info

Publication number: JPS6229559A
Authority: JP; Japan
Prior art keywords: group; hydrogen; formula; alkanoyloxy; acid
Prior art date: 1985-07-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP17584286A

Other languages

English (en)

Japanese (ja)

Inventor

ユルゲン・エンゲル

ベルンハルト・クチヤー

ゲルハルト・エーペン

ゲオルク・ニーブフ

ペーター・メツエナウアー

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Evonik Operations GmbH

Original Assignee

Degussa GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-31

Filing date

1986-07-28

Publication date

1987-02-07

1986-07-28 Application filed by Degussa GmbH filed Critical Degussa GmbH

1987-02-07 Publication of JPS6229559A publication Critical patent/JPS6229559A/ja

Status Pending legal-status Critical Current

Links

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235000019341 magnesium sulphate Nutrition 0.000 description 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
239000011976 maleic acid Substances 0.000 description 1
239000001630 malic acid Substances 0.000 description 1
239000011159 matrix material Substances 0.000 description 1
235000013336 milk Nutrition 0.000 description 1
239000008267 milk Substances 0.000 description 1
210000004080 milk Anatomy 0.000 description 1
238000002156 mixing Methods 0.000 description 1
150000002763 monocarboxylic acids Chemical class 0.000 description 1
230000002107 myocardial effect Effects 0.000 description 1
229910000069 nitrogen hydride Inorganic materials 0.000 description 1
238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
229940126701 oral medication Drugs 0.000 description 1
235000006408 oxalic acid Nutrition 0.000 description 1
125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 description 1
229920002866 paraformaldehyde Polymers 0.000 description 1
239000011886 peripheral blood Substances 0.000 description 1
210000005259 peripheral blood Anatomy 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 description 1
ABLZXFCXXLZCGV-UHFFFAOYSA-N phosphonic acid group Chemical group P(O)(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
125000001557 phthalyl group Chemical group C(=O)(O)C1=C(C(=O)*)C=CC=C1 0.000 description 1
229920006324 polyoxymethylene Polymers 0.000 description 1
229920005990 polystyrene resin Polymers 0.000 description 1
235000011118 potassium hydroxide Nutrition 0.000 description 1
235000019260 propionic acid Nutrition 0.000 description 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
238000010992 reflux Methods 0.000 description 1
238000000926 separation method Methods 0.000 description 1
RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
150000003388 sodium compounds Chemical class 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000007921 spray Substances 0.000 description 1
125000000542 sulfonic acid group Chemical group 0.000 description 1
239000000829 suppository Substances 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
238000010408 sweeping Methods 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 description 1
125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
238000009941 weaving Methods 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP17584286A 1985-07-31 1986-07-28 新規脂環式ケトアミン、その製法及びこれを含有する心臓機能改良剤 Pending JPS6229559A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE3527355		1985-07-31
DE3527355.0		1985-07-31
DE3530789.7		1985-08-29

Publications (1)

Publication Number	Publication Date
JPS6229559A true JPS6229559A (ja)	1987-02-07

Family

ID=6277223

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP17584286A Pending JPS6229559A (ja)	1985-07-31	1986-07-28	新規脂環式ケトアミン、その製法及びこれを含有する心臓機能改良剤

Country Status (3)

Country	Link
JP (1)	JPS6229559A (de)
DD (1)	DD259848A5 (de)
ZA (1)	ZA865701B (de)

1986
- 1986-07-28 JP JP17584286A patent/JPS6229559A/ja active Pending
- 1986-07-30 ZA ZA865701A patent/ZA865701B/xx unknown
- 1986-07-30 DD DD29314686A patent/DD259848A5/de unknown

Also Published As

Publication number	Publication date
DD259848A5 (de)	1988-09-07
ZA865701B (en)	1987-03-25

Publication	Publication Date	Title
US3341584A (en)	1967-09-12	Anilides
EP0279281B1 (de)	1992-08-26	Lipoxygenasehemmende Verbindungen
EP0091468B1 (de)	1987-08-19	1-2(benzoxazolyl)hydrazinoalkylnitrilabkömmlinge
US3341594A (en)	1967-09-12	1-(3, 5-dihydroxy-phenyl)-1-hydroxy-2-isopropylamino-ethane and salts thereof
JPH06506467A (ja)	1994-07-21	多環式三級アミンポリ芳香族スクアレンシンセターゼインヒビター
JPS5921684A (ja)	1984-02-03	３−アミノキヌクリジン誘導体、該誘導体の製法及び該誘導体を用いた治療上用の薬剤
CN86105400A (zh)	1987-03-11	茶醚
JPH0579057B2 (de)	1993-11-01
JPH02292272A (ja)	1990-12-03	抗高血糖症剤として有用な新規ナフタレニルアルキル―３ｈ―１，２，３，５―オキサチアジアゾール２―オキシド類
US4147780A (en)	1979-04-03	α-Amino-phosphonous acids for inhibiting bacteria and yeast
EP0047536A2 (de)	1982-03-17	Substituierte Propylamine
US4348402A (en)	1982-09-07	2-Hydroxyalkyl-3,4,5-trihydroxy-piperidine compounds, their production and their medicinal use
US3755413A (en)	1973-08-28	1-cyanophenoxy-2-hydroxy-3-(cycloalkyl-amino)-propanes
JPS5838263A (ja)	1983-03-05	ピリダジン誘導体
JPS62230767A (ja)	1987-10-09	アセトアミド誘導体、その製造方法およびその医薬への応用
US3192253A (en)	1965-06-29	N-substituted methoxyphenoxy-ethylamines
US3655743A (en)	1972-04-11	Substituted 4 - biphenyl-4-hydroxy crotonic acids and salts thereof
AU672989B2 (en)	1996-10-24	Pharmacologically active alpha-(tertiary-aminomethyl)-benzenemethanol derivatives
US3344188A (en)	1967-09-26	d (-)-n-tert.butyl- and -n-isopropyl-1-phenyl-2-amino-ethanols
US3478149A (en)	1969-11-11	Therapeutic compositions and methods employing sulfonamidophenethanolamines
JPS6229559A (ja)	1987-02-07	新規脂環式ケトアミン、その製法及びこれを含有する心臓機能改良剤
JPS63183542A (ja)	1988-07-28	置換オクタヒドロフェナントレン
US2431285A (en)	1947-11-18	Process for preparing 1-(dihydroxy-phenyl)-2-amino butanol-1 and intermediates
EP0005091B1 (de)	1981-11-25	Monosubstituierte Piperazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
JPH06511259A (ja)	1994-12-15	治療用アミン