JPS62500402A - 生体臨床医学用血漿の膜分離装置 - Google Patents
生体臨床医学用血漿の膜分離装置Info
- Publication number
- JPS62500402A JPS62500402A JP61501982A JP50198286A JPS62500402A JP S62500402 A JPS62500402 A JP S62500402A JP 61501982 A JP61501982 A JP 61501982A JP 50198286 A JP50198286 A JP 50198286A JP S62500402 A JPS62500402 A JP S62500402A
- Authority
- JP
- Japan
- Prior art keywords
- pivot pin
- rotor
- spinner
- seal
- disposable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000926 separation method Methods 0.000 title description 6
- 239000003814 drug Substances 0.000 title description 3
- 210000000170 cell membrane Anatomy 0.000 title 1
- 239000004033 plastic Substances 0.000 claims description 36
- 229920003023 plastic Polymers 0.000 claims description 36
- 229920000642 polymer Polymers 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 16
- 210000004369 blood Anatomy 0.000 claims description 14
- 239000008280 blood Substances 0.000 claims description 14
- 239000012528 membrane Substances 0.000 claims description 14
- 238000001914 filtration Methods 0.000 claims description 13
- 239000011347 resin Substances 0.000 claims description 8
- 229920005989 resin Polymers 0.000 claims description 8
- 239000012530 fluid Substances 0.000 claims description 7
- 238000002347 injection Methods 0.000 claims description 7
- 239000007924 injection Substances 0.000 claims description 7
- 238000001746 injection moulding Methods 0.000 claims description 7
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- 230000004048 modification Effects 0.000 claims description 4
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- 229920001296 polysiloxane Polymers 0.000 claims description 4
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- 230000003993 interaction Effects 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 229920006122 polyamide resin Polymers 0.000 claims description 2
- 238000005374 membrane filtration Methods 0.000 claims 8
- 210000002381 plasma Anatomy 0.000 claims 6
- 239000000314 lubricant Substances 0.000 claims 2
- 239000004952 Polyamide Substances 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 239000000565 sealant Substances 0.000 claims 1
- 229910001220 stainless steel Inorganic materials 0.000 description 8
- 239000010935 stainless steel Substances 0.000 description 8
- 238000012546 transfer Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 238000005498 polishing Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 230000008878 coupling Effects 0.000 description 5
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- 229920001343 polytetrafluoroethylene Polymers 0.000 description 5
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- 230000005855 radiation Effects 0.000 description 5
- 239000000306 component Substances 0.000 description 4
- 206010073306 Exposure to radiation Diseases 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000005461 lubrication Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
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- 238000000605 extraction Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 229920001721 polyimide Polymers 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N 1,1-Diethoxyethane Chemical compound CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- BQCIDUSAKPWEOX-UHFFFAOYSA-N 1,1-Difluoroethene Chemical compound FC(F)=C BQCIDUSAKPWEOX-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- GUTLYIVDDKVIGB-OUBTZVSYSA-N Cobalt-60 Chemical compound [60Co] GUTLYIVDDKVIGB-OUBTZVSYSA-N 0.000 description 1
- 229920004943 Delrin® Polymers 0.000 description 1
- 241000257465 Echinoidea Species 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229920002292 Nylon 6 Polymers 0.000 description 1
- 229920000572 Nylon 6/12 Polymers 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000004963 Torlon Substances 0.000 description 1
- 229920003997 Torlon® Polymers 0.000 description 1
- 229920004738 ULTEM® Polymers 0.000 description 1
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 1
- 239000011354 acetal resin Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000004917 carbon fiber Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- ZMUCVNSKULGPQG-UHFFFAOYSA-N dodecanedioic acid;hexane-1,6-diamine Chemical compound NCCCCCCN.OC(=O)CCCCCCCCCCC(O)=O ZMUCVNSKULGPQG-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 229920001973 fluoroelastomer Polymers 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- HCDGVLDPFQMKDK-UHFFFAOYSA-N hexafluoropropylene Chemical group FC(F)=C(F)C(F)(F)F HCDGVLDPFQMKDK-UHFFFAOYSA-N 0.000 description 1
- 150000003949 imides Chemical class 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 230000005541 medical transmission Effects 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000009719 polyimide resin Substances 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
- F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
- F16C33/02—Parts of sliding-contact bearings
- F16C33/04—Brasses; Bushes; Linings
- F16C33/20—Sliding surface consisting mainly of plastics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/26—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving
- A61M1/262—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving rotating
- A61M1/265—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving rotating inducing Taylor vortices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/06—Tubular membrane modules
- B01D63/062—Tubular membrane modules with membranes on a surface of a support tube
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/16—Rotary, reciprocated or vibrated modules
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
- F16C17/00—Sliding-contact bearings for exclusively rotary movement
- F16C17/04—Sliding-contact bearings for exclusively rotary movement for axial load only
- F16C17/08—Sliding-contact bearings for exclusively rotary movement for axial load only for supporting the end face of a shaft or other member, e.g. footstep bearings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/02—Rotation or turning
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Centrifugal Separators (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Prostheses (AREA)
- Pivots And Pivotal Connections (AREA)
- Sliding-Contact Bearings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/722,707 US4675106A (en) | 1985-04-12 | 1985-04-12 | Pivot pin bearing for biomedical systems |
| US722707 | 1985-04-12 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4242707A Division JP2530978B2 (ja) | 1985-04-12 | 1992-08-18 | 使い捨て式膜濾過装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62500402A true JPS62500402A (ja) | 1987-02-19 |
| JPH058986B2 JPH058986B2 (2) | 1993-02-03 |
Family
ID=24903034
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61501982A Granted JPS62500402A (ja) | 1985-04-12 | 1986-03-21 | 生体臨床医学用血漿の膜分離装置 |
| JP4242707A Expired - Lifetime JP2530978B2 (ja) | 1985-04-12 | 1992-08-18 | 使い捨て式膜濾過装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4242707A Expired - Lifetime JP2530978B2 (ja) | 1985-04-12 | 1992-08-18 | 使い捨て式膜濾過装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4675106A (2) |
| EP (1) | EP0218638B1 (2) |
| JP (2) | JPS62500402A (2) |
| AT (1) | ATE66382T1 (2) |
| DE (1) | DE3680983D1 (2) |
| WO (1) | WO1986005998A1 (2) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0691201A (ja) * | 1985-04-12 | 1994-04-05 | Baxter Internatl Inc | 使い捨て式膜濾過装置 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4790942A (en) * | 1983-12-20 | 1988-12-13 | Membrex Incorporated | Filtration method and apparatus |
| AU611648B2 (en) * | 1986-08-11 | 1991-06-20 | Baxter International Inc. | Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges |
| US4965846A (en) * | 1986-08-11 | 1990-10-23 | Baxter International Inc. | Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges |
| SE459715B (sv) * | 1986-09-08 | 1989-07-31 | Karl J Allsing | Foerfarande vid s.k.roterande filter samt filter |
| US4867878A (en) * | 1988-06-09 | 1989-09-19 | Membrex, Inc. | Liquid bearing for rotary apparatus |
| US4935002A (en) * | 1988-06-29 | 1990-06-19 | Biodynamics, Inc. | Apparatus and method for the autotransfusion of blood |
| US5004540A (en) * | 1989-12-01 | 1991-04-02 | Ketema Process Equipment Division | Invertible filter-type centrifuge with improved bearing and seal assembly |
| US5298016A (en) * | 1992-03-02 | 1994-03-29 | Advanced Haemotechnologies | Apparatus for separating plasma and other wastes from blood |
| US5487719A (en) * | 1994-01-14 | 1996-01-30 | Denver Instrument Company | Centrifuge rotor assembly |
| US6251295B1 (en) | 1998-01-08 | 2001-06-26 | Nexell Therapeutics Inc. | Method for recirculation washing of blood cells |
| US6773389B2 (en) | 2000-11-02 | 2004-08-10 | Gambro Inc | Fluid separation devices, systems and/or methods using a fluid pressure driven and/or balanced configuration |
| EP1509306B1 (en) * | 2002-05-30 | 2008-07-23 | Kkj, Inc. | Vortex enhanced filtration device and methods |
| AU2004220569B2 (en) * | 2003-03-10 | 2009-12-03 | Kkj, Inc. | Vortex-enhanced filtration devices |
| AU2004322685B2 (en) | 2004-08-20 | 2009-04-23 | Kkj, Inc. | Two stage hemofiltration that generates replacement fluid |
| US7374677B2 (en) * | 2004-08-20 | 2008-05-20 | Kkj, Inc. | Two stage hemofiltration that generates replacement fluid |
| AU2011207357A1 (en) * | 2010-01-21 | 2012-08-09 | Kkj, Inc. | Vortex-enhanced filtration devices |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59155758A (ja) * | 1982-12-13 | 1984-09-04 | ウイリアム・エフ・マツクロ−リン | 血液の分別装置および分別法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE557363A (2) * | 1956-06-16 | |||
| US3448858A (en) * | 1968-07-25 | 1969-06-10 | Ingersoll Rand Canada | Centrifugal filtering apparatus |
| FR2251230A5 (en) * | 1973-11-09 | 1975-06-06 | Cons Foods Corp | Roller assembly - with in situ moulded inner bearing stator member |
| DD126140A1 (2) * | 1975-12-06 | 1977-06-22 | ||
| US4776964A (en) * | 1984-08-24 | 1988-10-11 | William F. McLaughlin | Closed hemapheresis system and method |
| US4675106A (en) * | 1985-04-12 | 1987-06-23 | Hemascience Laboratories, Inc. | Pivot pin bearing for biomedical systems |
-
1985
- 1985-04-12 US US06/722,707 patent/US4675106A/en not_active Expired - Lifetime
-
1986
- 1986-03-21 AT AT86902224T patent/ATE66382T1/de active
- 1986-03-21 DE DE8686902224T patent/DE3680983D1/de not_active Expired - Lifetime
- 1986-03-21 EP EP86902224A patent/EP0218638B1/en not_active Expired
- 1986-03-21 WO PCT/US1986/000586 patent/WO1986005998A1/en not_active Ceased
- 1986-03-21 JP JP61501982A patent/JPS62500402A/ja active Granted
-
1992
- 1992-08-18 JP JP4242707A patent/JP2530978B2/ja not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59155758A (ja) * | 1982-12-13 | 1984-09-04 | ウイリアム・エフ・マツクロ−リン | 血液の分別装置および分別法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0691201A (ja) * | 1985-04-12 | 1994-04-05 | Baxter Internatl Inc | 使い捨て式膜濾過装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1986005998A1 (en) | 1986-10-23 |
| JPH058986B2 (2) | 1993-02-03 |
| JP2530978B2 (ja) | 1996-09-04 |
| EP0218638A4 (en) | 1987-09-30 |
| EP0218638B1 (en) | 1991-08-21 |
| ATE66382T1 (de) | 1991-09-15 |
| DE3680983D1 (de) | 1991-09-26 |
| US4675106A (en) | 1987-06-23 |
| EP0218638A1 (en) | 1987-04-22 |
| JPH0691201A (ja) | 1994-04-05 |
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