JPS6419025A - Active substance release-delayed oral medicine - Google Patents

Active substance release-delayed oral medicine

Info

Publication number: JPS6419025A
Authority: JP; Japan
Prior art keywords: active substance; formula; oral medicine; dioxan; decomposable
Prior art date: 1987-01-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP63010562A

Other languages

English (en)

Other versions

JP2744240B2 (ja

Inventor

Tsuiirenberugu Berunto

Furointo Berunharuto

Bendeikusu Deiiteru

Entenman Giyunteru

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim GmbH

Original Assignee

Boehringer Ingelheim GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-21

Filing date

1988-01-20

Publication date

1989-01-23

1988-01-20 Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH

1989-01-23 Publication of JPS6419025A publication Critical patent/JPS6419025A/ja

1998-04-28 Application granted granted Critical

1998-04-28 Publication of JP2744240B2 publication Critical patent/JP2744240B2/ja

2013-04-28 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000013543 active substance Substances 0.000 title abstract 3
239000003814 drug Substances 0.000 title 1
-1 cyclic carboxylic acid ester Chemical class 0.000 abstract 4
229940126701 oral medication Drugs 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000011248 coating agent Substances 0.000 abstract 1
239000011247 coating layer Substances 0.000 abstract 1
238000000576 coating method Methods 0.000 abstract 1
229920001577 copolymer Polymers 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
239000008187 granular material Substances 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 abstract 1
150000002596 lactones Chemical class 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008188 pellet Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
239000003826 tablet Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

JP63010562A 1987-01-21 1988-01-20 活性物質の放出を遅延させた経口医薬製剤 Expired - Lifetime JP2744240B2 (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19873701625 DE3701625A1 (de)	1987-01-21	1987-01-21	Perorale arzneimittelzubereitung mit verzoegerter wirkstofffreigabe
DE3701625.3		1987-01-21

Publications (2)

Publication Number	Publication Date
JPS6419025A true JPS6419025A (en)	1989-01-23
JP2744240B2 JP2744240B2 (ja)	1998-04-28

Family

ID=6319213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP63010562A Expired - Lifetime JP2744240B2 (ja)	1987-01-21	1988-01-20	活性物質の放出を遅延させた経口医薬製剤

Country Status (14)

Country	Link
EP (1)	EP0275961B1 (ja)
JP (1)	JP2744240B2 (ja)
KR (1)	KR970002615B1 (ja)
AT (1)	ATE106718T1 (ja)
AU (1)	AU605824B2 (ja)
CA (1)	CA1329767C (ja)
DE (2)	DE3701625A1 (ja)
DK (1)	DK23588A (ja)
FI (1)	FI93425C (ja)
IL (1)	IL85144A (ja)
MX (1)	MX10146A (ja)
NO (1)	NO175352C (ja)
NZ (1)	NZ223228A (ja)
ZA (1)	ZA88358B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4981696A (en) *	1986-12-22	1991-01-01	E. I. Du Pont De Nemours And Company	Polylactide compositions
US4902515A (en) *	1988-04-28	1990-02-20	E. I. Dupont De Nemours And Company	Polylactide compositions
FR2634770B1 (fr) *	1988-07-29	1990-10-05	Rhone Poulenc Chimie	Composition polyester erodable contenant de l'iode pour le traitement des eaux
DE59003337D1 (de) *	1989-10-16	1993-12-09	Danubia Petrochem Polymere	Pressling mit retardierter Wirkstofffreisetzung.
DE4041563A1 (de) *	1990-12-22	1992-06-25	Sanol Arznei Schwarz Gmbh	Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren
DE19500977C2 (de) *	1995-01-14	1999-01-07	Lohmann Therapie Syst Lts	Feste Arzneimittelform mit in polymerem Material verteiltem Wirkstoff
DE19908753C2 (de) *	1999-02-20	2003-10-02	Jenapharm Gmbh	Bioabbaubare, injizierbare Oligomer-Polymer-Zusammensetzung
WO2015184256A2 (en)	2014-05-30	2015-12-03	Shire Human Genetic Therapies, Inc.	Biodegradable lipids for delivery of nucleic acids

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5966425A (ja) *	1982-10-08	1984-04-14	Mitsui Toatsu Chem Inc	生体分解性重合体を用いた微小粒子の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3773919A (en) *	1969-10-23	1973-11-20	Du Pont	Polylactide-drug mixtures
CA1098443A (en) *	1977-05-20	1981-03-31	Namassivaya Doddi	Absorbable p-dioxanone polymer-drug compositions
DE2824112A1 (de) *	1978-06-01	1979-12-06	Garching Instrumente	Mikropellets, verfahren zu ihrer herstellung und deren verwendung
IE52535B1 (en) *	1981-02-16	1987-12-09	Ici Plc	Continuous release pharmaceutical compositions
FR2557459B1 (fr) *	1984-01-02	1986-05-30	Lhd Lab Hygiene Dietetique	Matrice inerte a base de polycaprolactone pour administration orale d'un medicament, et procede de preparation de la forme galenique comprenant cette matrice

1987
- 1987-01-21 DE DE19873701625 patent/DE3701625A1/de not_active Ceased
1988
- 1988-01-19 DE DE3889933T patent/DE3889933D1/de not_active Expired - Fee Related
- 1988-01-19 NZ NZ223228A patent/NZ223228A/en unknown
- 1988-01-19 EP EP88100636A patent/EP0275961B1/de not_active Expired - Lifetime
- 1988-01-19 AT AT88100636T patent/ATE106718T1/de not_active IP Right Cessation
- 1988-01-19 FI FI880210A patent/FI93425C/fi not_active IP Right Cessation
- 1988-01-19 MX MX1014688A patent/MX10146A/es unknown
- 1988-01-20 IL IL85144A patent/IL85144A/xx not_active IP Right Cessation
- 1988-01-20 JP JP63010562A patent/JP2744240B2/ja not_active Expired - Lifetime
- 1988-01-20 ZA ZA88358A patent/ZA88358B/xx unknown
- 1988-01-20 NO NO880230A patent/NO175352C/no not_active IP Right Cessation
- 1988-01-20 CA CA000556899A patent/CA1329767C/en not_active Expired - Fee Related
- 1988-01-20 KR KR1019880000394A patent/KR970002615B1/ko not_active Expired - Fee Related
- 1988-01-20 DK DK023588A patent/DK23588A/da not_active Application Discontinuation
- 1988-01-21 AU AU10653/88A patent/AU605824B2/en not_active Ceased

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5966425A (ja) *	1982-10-08	1984-04-14	Mitsui Toatsu Chem Inc	生体分解性重合体を用いた微小粒子の製造方法

Also Published As

Publication number	Publication date
CA1329767C (en)	1994-05-24
ZA88358B (en)	1989-09-27
FI93425B (fi)	1994-12-30
FI880210L (fi)	1988-07-22
EP0275961A3 (en)	1990-11-22
IL85144A (en)	1991-06-30
AU1065388A (en)	1988-07-28
FI93425C (fi)	1995-04-10
IL85144A0 (en)	1988-06-30
NO880230L (no)	1988-07-22
DE3701625A1 (de)	1988-08-04
NZ223228A (en)	1990-12-21
KR970002615B1 (ko)	1997-03-06
NO880230D0 (no)	1988-01-20
NO175352C (no)	1994-10-05
EP0275961B1 (de)	1994-06-08
MX10146A (es)	1993-09-01
ATE106718T1 (de)	1994-06-15
DK23588D0 (da)	1988-01-20
AU605824B2 (en)	1991-01-24
KR880008806A (ko)	1988-09-13
JP2744240B2 (ja)	1998-04-28
EP0275961A2 (de)	1988-07-27
NO175352B (no)	1994-06-27
FI880210A0 (fi)	1988-01-19
DK23588A (da)	1988-07-22
DE3889933D1 (de)	1994-07-14

Publication	Publication Date	Title
PH23993A (en)	1990-02-09	Controlled absorption pharmaceutical composition
ES2000269A6 (es)	1988-02-01	Procedimiento para preparar formas medicamentosas solidas, que contienen 9-desoxo-11-desoxi-9,11-(iminon2-(2-metoxietoxi)-etiliden)-oxi-(9s)-eritromicina como substancia activa
GEP19991686B (en)	1999-08-05	Pharmaceutical Composition for Obtaining Effervescent Powder or Tablet, Pharmaceutical Preparation and Method for Preparing Same
ATE172183T1 (de)	1998-10-15	Ester und kombinationen von einem organischen nitrat und einem salicyclat
DE3689983D1 (de)	1994-08-25	Arzneimittel mit langsamer Wirkstofffreisetzung.
HU892559D0 (en)	1990-01-28	Process for the preparation of transdermal pharmaceutical composition suitable for systemic administration, containing deprenyl as active ingredient
AU1196988A (en)	1988-08-25	Process for preparing a retard product containing diltiazem for a single daily administration
HUT38097A (en)	1986-04-28	Process for preparing substituted benzopyrans and pharmaceutical compositions containing them as active substances
PH25545A (en)	1991-08-08	Sustained release multi-granule tablet
IL85144A (en)	1991-06-30	Controlled release oral pharmaceutical compositions containing cyclic carboxylic acid esters or their polymers as carrier or coating material and their preparation
KR860006265A (ko)	1986-09-09	9,10-디하이드로 에르고트 알카로이드를 함유하는 서방성 제재의 제조방법
ES500670A0 (es)	1984-07-01	Procedimiento de preparar farmacos con liberacion programada de materia activa.
HUT49135A (en)	1989-08-28	Process for production of cyclic carbonic acids, cyclic alcohols and amin-esthers and their amids and medical compounds containing them as active substance
KR900001701A (ko)	1990-02-27	이미다조피라졸 유도체의 진통제 및 항염제로서의 용도
PT84580A (en)	1987-04-01	Process for the preparation of pharmaceutical compositions containing indomethacin
IL82639A0 (en)	1987-11-30	Transdermal pharmaceutical composition
RU96123569A (ru)	1999-01-27	Лекарственный препарат
JPS5350319A (en)	1978-05-08	Drug discharging means of medical capsule
KR870000067A (ko)	1987-02-16	조절된 서방성을 지닌 활성제의 고형분산액
ES2004693A6 (es)	1989-02-01	Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo.
JPS6429313A (en)	1989-01-31	Enzyme inhibitor
GB2001966A (en)	1979-02-14	Penicillin esters and their preparation
JPS6440427A (en)	1989-02-10	5-lipoxygenase action inhibitor
FR2637287B1 (fr)	1992-07-17	Esters de l'hydroxy-2((pyrrolidinyl-1)-2 ethoxy)-5 p-cymene, le procede de preparation desdits produits, et les medicaments contenant lesdits composes comme principe actif