JPS643182A - Carbostyril derivative - Google Patents

Carbostyril derivative

Info

Publication number: JPS643182A
Authority: JP; Japan
Prior art keywords: formula; expressed; reacted; increasing action; carbostyril derivative
Prior art date: 1987-06-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP15688787A

Other languages

English (en)

Other versions

JPH0745493B2 (ja

JPH013182A (ja

Inventor

Shigeharu Tamada

Takafumi Fujioka

Hidenori Ogawa

Shuji Teramoto

Kazumi Kondo

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Otsuka Pharmaceutical Co Ltd

Original Assignee

Otsuka Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-24

Filing date

1987-06-24

Publication date

1989-01-06

1987-06-24 Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd

1987-06-24 Priority to JP15688787A priority Critical patent/JPH0745493B2/ja

1987-07-30 Priority to US07/079,875 priority patent/US4886809A/en

1987-07-30 Priority to DK397387A priority patent/DK397387A/da

1987-07-30 Priority to EP87111045A priority patent/EP0255134B1/en

1987-07-30 Priority to DE8787111045T priority patent/DE3784401T2/de

1987-07-30 Priority to ES87111045T priority patent/ES2053480T3/es

1987-07-31 Priority to KR1019870008446A priority patent/KR880001601A/ko

1989-01-06 Publication of JPS643182A publication Critical patent/JPS643182A/ja

1989-01-06 Publication of JPH013182A publication Critical patent/JPH013182A/ja

1989-09-11 Priority to US07/405,295 priority patent/US5071856A/en

1995-05-17 Publication of JPH0745493B2 publication Critical patent/JPH0745493B2/ja

2010-05-17 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 2
ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
230000001965 increasing effect Effects 0.000 abstract 2
208000001953 Hypotension Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000008065 acid anhydrides Chemical class 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
239000000496 cardiotonic agent Substances 0.000 abstract 1
230000003177 cardiotonic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
208000021822 hypotensive Diseases 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
230000000297 inotrophic effect Effects 0.000 abstract 1
231100000053 low toxicity Toxicity 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
XMJHPCRAQCTCFT-UHFFFAOYSA-N methyl chloroformate Chemical compound COC(Cl)=O XMJHPCRAQCTCFT-UHFFFAOYSA-N 0.000 abstract 1
VABGRYQJOPKALR-UHFFFAOYSA-N n-[1-(2-oxo-3,4-dihydro-1h-quinolin-6-yl)piperidin-4-yl]propanamide Chemical compound C1CC(NC(=O)CC)CCN1C1=CC=C(NC(=O)CC2)C2=C1 VABGRYQJOPKALR-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Landscapes

Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP15688787A 1986-07-31 1987-06-24 カルボスチリル誘導体 Expired - Lifetime JPH0745493B2 (ja)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
JP15688787A JPH0745493B2 (ja)	1987-06-24	1987-06-24	カルボスチリル誘導体
ES87111045T ES2053480T3 (es)	1986-07-31	1987-07-30	Un procedimiento para preparar un derivado de carboestirilo.
DK397387A DK397387A (da)	1986-07-31	1987-07-30	Carbostyrilderivater og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
EP87111045A EP0255134B1 (en)	1986-07-31	1987-07-30	Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same
DE8787111045T DE3784401T2 (de)	1986-07-31	1987-07-30	Karbostyril-derivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende kardiotonische zusammensetzung.
US07/079,875 US4886809A (en)	1986-07-31	1987-07-30	Carbostyril derivatives and salts thereof
KR1019870008446A KR880001601A (ko)	1986-07-31	1987-07-31	신규 카르보스티릴 유도체 및 그의 염
US07/405,295 US5071856A (en)	1986-07-31	1989-09-11	Carbostyril derivatives and salts thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP15688787A JPH0745493B2 (ja)	1987-06-24	1987-06-24	カルボスチリル誘導体

Publications (3)

Publication Number	Publication Date
JPS643182A true JPS643182A (en)	1989-01-06
JPH013182A JPH013182A (ja)	1989-01-06
JPH0745493B2 JPH0745493B2 (ja)	1995-05-17

Family

ID=15637565

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP15688787A Expired - Lifetime JPH0745493B2 (ja)	1986-07-31	1987-06-24	カルボスチリル誘導体

Country Status (1)

Country	Link
JP (1)	JPH0745493B2 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001053258A1 (en) *	2000-01-20	2001-07-26	Eisai Co., Ltd.	Nitrogenous cyclic compounds and pharmaceutical compositions containing the same

1987
- 1987-06-24 JP JP15688787A patent/JPH0745493B2/ja not_active Expired - Lifetime

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001053258A1 (en) *	2000-01-20	2001-07-26	Eisai Co., Ltd.	Nitrogenous cyclic compounds and pharmaceutical compositions containing the same
US6906072B1 (en)	2000-01-20	2005-06-14	Eisai Co., Ltd.	Piperazine compound and pharmaceutical composition containing the compound

Also Published As

Publication number	Publication date
JPH0745493B2 (ja)	1995-05-17

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