JPS6460396A - Production of 2'-deoxycytidine - Google Patents

Production of 2'-deoxycytidine

Info

Publication number
JPS6460396A
JPS6460396A JP62214783A JP21478387A JPS6460396A JP S6460396 A JPS6460396 A JP S6460396A JP 62214783 A JP62214783 A JP 62214783A JP 21478387 A JP21478387 A JP 21478387A JP S6460396 A JPS6460396 A JP S6460396A
Authority
JP
Japan
Prior art keywords
deoxycytidine
deoxyribose
cytosine
phosphoric acid
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62214783A
Other languages
Japanese (ja)
Other versions
JPH0789948B2 (en
Inventor
Kenzo Yokozeki
Hideyuki Shirae
Koji Kubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP62214783A priority Critical patent/JPH0789948B2/en
Publication of JPS6460396A publication Critical patent/JPS6460396A/en
Publication of JPH0789948B2 publication Critical patent/JPH0789948B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE:To obtain 2'-deoxycytidine useful as a raw material for 2',3'- dideoxycytidine known as a remedy for AIDS, in high efficiency, by reacting 2'-deoxyribose-1-phosphoric acid or its salt with cytosine in the presence of a specific microorganism. CONSTITUTION:2'-Deoxyribonucleoside (2'-deoxyadenosine, etc.) or 2'- deoxyribose-1-phosphoric acid present in the hydrolyzed product of DNA (excluding 2'-deoxycytidine) is made to react with cytosine in an aqueous medium containing a microbial strain belonging to Achromobacter genus, Aeromonas genus, etc., and capable of producing 2'-deoxycytidine from cytosine and 2'- deoxyribose-1-phosphoric acid or its salt, e.g. Achromobacter viscosus ATCC-12448.
JP62214783A 1987-08-28 1987-08-28 2 ▲ '▼ -Method for producing deoxycytidine Expired - Lifetime JPH0789948B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62214783A JPH0789948B2 (en) 1987-08-28 1987-08-28 2 ▲ '▼ -Method for producing deoxycytidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62214783A JPH0789948B2 (en) 1987-08-28 1987-08-28 2 ▲ '▼ -Method for producing deoxycytidine

Publications (2)

Publication Number Publication Date
JPS6460396A true JPS6460396A (en) 1989-03-07
JPH0789948B2 JPH0789948B2 (en) 1995-10-04

Family

ID=16661464

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62214783A Expired - Lifetime JPH0789948B2 (en) 1987-08-28 1987-08-28 2 ▲ '▼ -Method for producing deoxycytidine

Country Status (1)

Country Link
JP (1) JPH0789948B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777208B2 (en) 2000-10-25 2004-08-17 Ajinomoto Co., Inc. Method for producing 2′ -deoxyribonucleoside
US6858721B2 (en) 2001-05-01 2005-02-22 Mitsui Chemicals, Inc. Method for producing cytosine nucleoside compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102794A (en) * 1979-05-01 1981-08-17 Ajinomoto Co Inc Preparation of pyrimidine ribonucleosides and pyrimidine deoxyribonucleosides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102794A (en) * 1979-05-01 1981-08-17 Ajinomoto Co Inc Preparation of pyrimidine ribonucleosides and pyrimidine deoxyribonucleosides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777208B2 (en) 2000-10-25 2004-08-17 Ajinomoto Co., Inc. Method for producing 2′ -deoxyribonucleoside
US7223589B2 (en) 2000-10-25 2007-05-29 Ajinomoto Co., Inc. Bacterium for the production of 2′-deoxyribonucleoside
US6858721B2 (en) 2001-05-01 2005-02-22 Mitsui Chemicals, Inc. Method for producing cytosine nucleoside compounds
US7629457B2 (en) 2001-05-01 2009-12-08 Mitsui Chemicals, Inc. Method for producing cytosine nucleoside compounds

Also Published As

Publication number Publication date
JPH0789948B2 (en) 1995-10-04

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term