JPS6466A - Production of 2-azetidinone derivative - Google Patents
Production of 2-azetidinone derivativeInfo
- Publication number
- JPS6466A JPS6466A JP63033283A JP3328388A JPS6466A JP S6466 A JPS6466 A JP S6466A JP 63033283 A JP63033283 A JP 63033283A JP 3328388 A JP3328388 A JP 3328388A JP S6466 A JPS6466 A JP S6466A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound shown
- formula
- enolate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 carboxylic acid ester compound Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000004705 aldimines Chemical class 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- JGHYBJVUQGTEEB-UHFFFAOYSA-M dimethylalumanylium;chloride Chemical compound C[Al](C)Cl JGHYBJVUQGTEEB-UHFFFAOYSA-M 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Plural Heterocyclic Compounds (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as an antimicrobial agent and an intermediate thereof in high yield, by reacting an aldimine derivative with an enolate of a carboxylic acid ester compound in the presence of a di-lower alkylaluminum halide.
CONSTITUTION: A compound shown by formula I (R1 is H, arylalkyl or imino- protecting group; R2 is H or alkyl; R3 is H, halogen or organic group) or a salt thereof is reacted with an enolate of a compound shown by formula II (R4 is H or alkyl; R5 is H or alkyl which may be replaced; R6 is ester residue) in the presence of a di-lower alkylaluminum halide (e.g. dimethylaluminum chloride) usually under cooling or at room temperature to give the aimed compound shown by formula III or a salt thereof.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63033283A JPS6466A (en) | 1987-02-20 | 1988-02-16 | Production of 2-azetidinone derivative |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62-38538 | 1987-02-20 | ||
| JP3853887 | 1987-02-20 | ||
| JP63033283A JPS6466A (en) | 1987-02-20 | 1988-02-16 | Production of 2-azetidinone derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0166A JPH0166A (en) | 1989-01-05 |
| JPS6466A true JPS6466A (en) | 1989-01-05 |
Family
ID=26371959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63033283A Pending JPS6466A (en) | 1987-02-20 | 1988-02-16 | Production of 2-azetidinone derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6466A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610763B1 (en) | 1998-01-22 | 2003-08-26 | Gebr. Otto Gmbh & Co. Kg | Polymer composition, the production and further processing thereof into receptacles |
-
1988
- 1988-02-16 JP JP63033283A patent/JPS6466A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610763B1 (en) | 1998-01-22 | 2003-08-26 | Gebr. Otto Gmbh & Co. Kg | Polymer composition, the production and further processing thereof into receptacles |
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