JPS6468363A - Macrocyclic polyamines having phenol group in ring and production thereof - Google Patents
Macrocyclic polyamines having phenol group in ring and production thereofInfo
- Publication number
- JPS6468363A JPS6468363A JP22404187A JP22404187A JPS6468363A JP S6468363 A JPS6468363 A JP S6468363A JP 22404187 A JP22404187 A JP 22404187A JP 22404187 A JP22404187 A JP 22404187A JP S6468363 A JPS6468363 A JP S6468363A
- Authority
- JP
- Japan
- Prior art keywords
- compound expressed
- ring
- production
- formula
- phenol group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A compound expressed by formula I (X is Cl, Br, I or H). USE:A chelating agent. PREPARATION:A compound expressed by formula II (R is alkyl) is subjected to cyclocondensation with a compound expressed by III (Ts is p-toluene sulfonyl) in a solvent such as DMF in the presence of a base catalyst (preferably NaH) at 60-140 deg.C and the resultant cyclocondensation product is hydrolyzed in the presence of a detosylation catalyst (e.g. hydrobromic acid/acetic acid mixture) and p-toluene sulfonyl group and alkyl group are removed to provide the compound expressed by formula I.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22404187A JPS6468363A (en) | 1987-09-09 | 1987-09-09 | Macrocyclic polyamines having phenol group in ring and production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22404187A JPS6468363A (en) | 1987-09-09 | 1987-09-09 | Macrocyclic polyamines having phenol group in ring and production thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6468363A true JPS6468363A (en) | 1989-03-14 |
Family
ID=16807668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22404187A Pending JPS6468363A (en) | 1987-09-09 | 1987-09-09 | Macrocyclic polyamines having phenol group in ring and production thereof |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6468363A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
| US11822171B2 (en) | 2017-04-27 | 2023-11-21 | Manufacturing Resources International, Inc. | Field serviceable and replaceable assembly |
-
1987
- 1987-09-09 JP JP22404187A patent/JPS6468363A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
| US5403572A (en) * | 1988-07-20 | 1995-04-04 | Schering Aktiengesellschaft | Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them |
| US11822171B2 (en) | 2017-04-27 | 2023-11-21 | Manufacturing Resources International, Inc. | Field serviceable and replaceable assembly |
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