JPS6497A - 16-membered ring macrolide compound - Google Patents
16-membered ring macrolide compoundInfo
- Publication number
- JPS6497A JPS6497A JP15482687A JP15482687A JPS6497A JP S6497 A JPS6497 A JP S6497A JP 15482687 A JP15482687 A JP 15482687A JP 15482687 A JP15482687 A JP 15482687A JP S6497 A JPS6497 A JP S6497A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- coc
- membered ring
- compound shown
- macrolide compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000003120 macrolide antibiotic agent Substances 0.000 title 1
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- HDFRDWFLWVCOGP-UHFFFAOYSA-N carbonothioic O,S-acid Chemical compound OC(S)=O HDFRDWFLWVCOGP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by formula I [n is 0 or 1; R0 is H or alkyl; A is OH, =0 or group shown by formula II; R1 is OCH3 or CH3; R2 is H or CH3; R3 is H, CH3, CH2OH or group shown by formula III; R4 is CH3 of C2H5; R5 is H, COCH3 or COC2H5; R6 is H or COC2H5, COC3H7 or COCH2 CH(CH3)2] and an acid addition salt thereof.
EXAMPLE: A compound shown by formula IV.
USE: An antimicrobial agent for oral administration.
PREPARATION: A compound shown by formula V is reacted with a mercaptocarboxylic acid in an organic solvent containing no active hydrogen in the presence of 1,3-dicyclohexylcarbodiimide and optionally a base at -25W60°C for 1W6 days.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15482687A JPS6497A (en) | 1987-06-22 | 1987-06-22 | 16-membered ring macrolide compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15482687A JPS6497A (en) | 1987-06-22 | 1987-06-22 | 16-membered ring macrolide compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0197A JPH0197A (en) | 1989-01-05 |
| JPS6497A true JPS6497A (en) | 1989-01-05 |
Family
ID=15592725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15482687A Pending JPS6497A (en) | 1987-06-22 | 1987-06-22 | 16-membered ring macrolide compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6497A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2012000933A1 (en) | 2011-04-14 | 2014-07-25 | Harnischfeger Tech Inc | A method and a cable shovel for the generation of an ideal path, comprises: an oscillation engine, a hoisting engine, a feed motor, a bucket for digging and emptying materials and, positioning the shovel by means of the operation of the lifting motor, feed motor and oscillation engine and; a controller that includes an ideal path generator module. |
-
1987
- 1987-06-22 JP JP15482687A patent/JPS6497A/en active Pending
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