KR20100105587A - 항-인자 b 항체 및 이들의 용도 - Google Patents
항-인자 b 항체 및 이들의 용도 Download PDFInfo
- Publication number
- KR20100105587A KR20100105587A KR1020107012466A KR20107012466A KR20100105587A KR 20100105587 A KR20100105587 A KR 20100105587A KR 1020107012466 A KR1020107012466 A KR 1020107012466A KR 20107012466 A KR20107012466 A KR 20107012466A KR 20100105587 A KR20100105587 A KR 20100105587A
- Authority
- KR
- South Korea
- Prior art keywords
- antibody
- factor
- ser
- complement
- val
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US264807P | 2007-11-08 | 2007-11-08 | |
| US61/002,648 | 2007-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100105587A true KR20100105587A (ko) | 2010-09-29 |
Family
ID=40344464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020107012466A Withdrawn KR20100105587A (ko) | 2007-11-08 | 2008-11-06 | 항-인자 b 항체 및 이들의 용도 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8158762B2 (2) |
| EP (1) | EP2209807A1 (2) |
| JP (1) | JP2011503094A (2) |
| KR (1) | KR20100105587A (2) |
| CN (1) | CN101918444A (2) |
| AR (1) | AR069233A1 (2) |
| AU (1) | AU2008323939A1 (2) |
| BR (1) | BRPI0820343A2 (2) |
| CA (1) | CA2704973A1 (2) |
| CL (1) | CL2008003313A1 (2) |
| IL (1) | IL205577A0 (2) |
| MX (1) | MX2010005115A (2) |
| PE (1) | PE20091022A1 (2) |
| TW (1) | TW200927170A (2) |
| WO (1) | WO2009061910A1 (2) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
| TWI407953B (zh) * | 2011-03-24 | 2013-09-11 | Univ Kaohsiung Medical | 用於調節補體因子b(cfb)表現的醫藥組合物 |
| US9803005B2 (en) | 2012-05-24 | 2017-10-31 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor B antibody |
| MY180626A (en) | 2013-11-15 | 2020-12-03 | Akebia Therapeutics Inc | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| EP3452510A4 (en) | 2016-04-04 | 2020-01-15 | Bioverativ USA Inc. | ANTI-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| EP4139350A4 (en) | 2020-04-20 | 2024-04-24 | Genzyme Corporation | Humanized anti-complement factor bb antibodies and uses thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク,インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| ATE207080T1 (de) | 1991-11-25 | 2001-11-15 | Enzon Inc | Multivalente antigen-bindende proteine |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| CA2488441C (en) | 2002-06-03 | 2015-01-27 | Genentech, Inc. | Synthetic antibody phage libraries |
| US20070123466A1 (en) * | 2003-05-13 | 2007-05-31 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method of treating recurrent miscarriages |
| BRPI0506629A (pt) * | 2004-02-10 | 2007-05-02 | Univ Colorado | inibição do fator b, a via alternativa do sistema complemento e métodos relacionados |
| SG10201804008UA (en) * | 2005-11-04 | 2018-06-28 | Genentech Inc | Use of complement pathway inhibitors to treat ocular diseases |
| NZ571791A (en) * | 2006-03-08 | 2012-03-30 | Archemix Llc | Complement binding aptamers and anti-C5 agents useful in the treatment of ocular disorders |
| JP5332064B2 (ja) * | 2007-03-01 | 2013-11-06 | ウェルスタット イムノセラピューティクス, エルエルシー | 炎症により特徴付けられる疾患の治療 |
-
2008
- 2008-11-06 US US12/291,222 patent/US8158762B2/en not_active Expired - Fee Related
- 2008-11-06 CA CA2704973A patent/CA2704973A1/en not_active Abandoned
- 2008-11-06 CN CN2008801243361A patent/CN101918444A/zh active Pending
- 2008-11-06 EP EP08848036A patent/EP2209807A1/en not_active Withdrawn
- 2008-11-06 BR BRPI0820343A patent/BRPI0820343A2/pt not_active IP Right Cessation
- 2008-11-06 MX MX2010005115A patent/MX2010005115A/es unknown
- 2008-11-06 AU AU2008323939A patent/AU2008323939A1/en not_active Abandoned
- 2008-11-06 JP JP2010533241A patent/JP2011503094A/ja active Pending
- 2008-11-06 KR KR1020107012466A patent/KR20100105587A/ko not_active Withdrawn
- 2008-11-06 WO PCT/US2008/082621 patent/WO2009061910A1/en not_active Ceased
- 2008-11-07 PE PE2008001904A patent/PE20091022A1/es not_active Application Discontinuation
- 2008-11-07 AR ARP080104888A patent/AR069233A1/es not_active Application Discontinuation
- 2008-11-07 CL CL2008003313A patent/CL2008003313A1/es unknown
- 2008-11-07 TW TW097143224A patent/TW200927170A/zh unknown
-
2010
- 2010-05-06 IL IL205577A patent/IL205577A0/en unknown
-
2012
- 2012-01-31 US US13/385,057 patent/US20120230997A1/en not_active Abandoned
-
2015
- 2015-10-06 US US14/876,655 patent/US20160024224A1/en not_active Abandoned
-
2017
- 2017-10-23 US US15/791,064 patent/US20180037667A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20180037667A1 (en) | 2018-02-08 |
| EP2209807A1 (en) | 2010-07-28 |
| WO2009061910A1 (en) | 2009-05-14 |
| US20090123469A1 (en) | 2009-05-14 |
| MX2010005115A (es) | 2010-05-27 |
| CL2008003313A1 (es) | 2010-02-05 |
| IL205577A0 (en) | 2010-11-30 |
| US20160024224A1 (en) | 2016-01-28 |
| CN101918444A (zh) | 2010-12-15 |
| US8158762B2 (en) | 2012-04-17 |
| AU2008323939A1 (en) | 2009-05-14 |
| AR069233A1 (es) | 2010-01-06 |
| JP2011503094A (ja) | 2011-01-27 |
| TW200927170A (en) | 2009-07-01 |
| US20120230997A1 (en) | 2012-09-13 |
| BRPI0820343A2 (pt) | 2017-08-22 |
| PE20091022A1 (es) | 2009-07-16 |
| CA2704973A1 (en) | 2009-05-14 |
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| US20180037667A1 (en) | Anti-factor b antibodies and their uses | |
| AU2017254945A1 (en) | Prevention and treatment of complement-associated eye conditions | |
| AU2013213753A1 (en) | Prevention and treatment of complement-associated eye conditions | |
| HK1139161B (en) | Prevention and treatment of complement- associated eye conditions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20100607 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |