KR20150102852A - 무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법 - Google Patents

무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법 Download PDF

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Publication number
KR20150102852A
KR20150102852A KR1020140024747A KR20140024747A KR20150102852A KR 20150102852 A KR20150102852 A KR 20150102852A KR 1020140024747 A KR1020140024747 A KR 1020140024747A KR 20140024747 A KR20140024747 A KR 20140024747A KR 20150102852 A KR20150102852 A KR 20150102852A
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South Korea
Prior art keywords
solifenacin
solid dispersion
pharmaceutically acceptable
amorphous
dispersion composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
KR1020140024747A
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English (en)
Korean (ko)
Inventor
유용원
강세연
송세현
손세일
이홍우
Original Assignee
대원제약주식회사
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Priority to KR1020140024747A priority Critical patent/KR20150102852A/ko
Priority to PCT/KR2015/001891 priority patent/WO2015130110A1/fr
Publication of KR20150102852A publication Critical patent/KR20150102852A/ko
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020140024747A 2014-02-28 2014-02-28 무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법 Withdrawn KR20150102852A (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020140024747A KR20150102852A (ko) 2014-02-28 2014-02-28 무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법
PCT/KR2015/001891 WO2015130110A1 (fr) 2014-02-28 2015-02-26 Composition de dispersion solide à stabilité accrue, contenant de la solifénacine amorphe ou un sel de celui-ci, et son procédé de préparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020140024747A KR20150102852A (ko) 2014-02-28 2014-02-28 무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법

Publications (1)

Publication Number Publication Date
KR20150102852A true KR20150102852A (ko) 2015-09-08

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Family Applications (1)

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KR1020140024747A Withdrawn KR20150102852A (ko) 2014-02-28 2014-02-28 무정형 솔리페나신 또는 그의 염을 포함하는 안정성이 증가된 고체분산체 조성물 및 그 제조방법

Country Status (2)

Country Link
KR (1) KR20150102852A (fr)
WO (1) WO2015130110A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017082577A1 (fr) * 2015-11-11 2017-05-18 한미약품 주식회사 Préparation solide contenant de la solifénacine amorphe à usage oral et son procédé de préparation
WO2018004270A1 (fr) * 2016-06-30 2018-01-04 한미약품 주식회사 Préparation solide administrée par voie orale contenant de la solifénacine amorphe et son procédé de préparation
KR20210114271A (ko) 2020-03-10 2021-09-23 주식회사 종근당 솔리페나신 또는 이의 약제학적으로 허용가능한 염을 함유하는 약제학적 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100137358A1 (en) * 1996-11-05 2010-06-03 Dr. Reddy's Laboratories Ltd. Solifenacin compositions
KR101836467B1 (ko) * 2004-03-25 2018-03-08 아스텔라스세이야쿠 가부시키가이샤 솔리페나신 또는 그의 염의 고형 제제용 조성물

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017082577A1 (fr) * 2015-11-11 2017-05-18 한미약품 주식회사 Préparation solide contenant de la solifénacine amorphe à usage oral et son procédé de préparation
WO2018004270A1 (fr) * 2016-06-30 2018-01-04 한미약품 주식회사 Préparation solide administrée par voie orale contenant de la solifénacine amorphe et son procédé de préparation
KR20210114271A (ko) 2020-03-10 2021-09-23 주식회사 종근당 솔리페나신 또는 이의 약제학적으로 허용가능한 염을 함유하는 약제학적 조성물
KR20230065222A (ko) 2020-03-10 2023-05-11 주식회사 종근당 솔리페나신 또는 이의 약제학적으로 허용가능한 염을 함유하는 약제학적 조성물

Also Published As

Publication number Publication date
WO2015130110A1 (fr) 2015-09-03

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