KR20200079292A - 항생제 내성을 치료하기 위한 조성물 및 방법 - Google Patents

Abstract

본 발명은 항생제 내성 유전자의 운반을 감소시키기 위한 조성물 및 방법에 관한 것이다.

Description

항생제 내성을 치료하기 위한 조성물 및 방법

본 발명은 항생제 내성 예방 및 치료에 관한 것이다.

세계 보건 기구 (WHO)에 따르면, 세균의 "항생제 내성은 오늘날 세계 보건, 식량 안보, 및 개발에 대한 가장 큰 위협 중 하나이다" (who.int/mediacentre/factsheets/antibiotic-resistance/en). 항생제 내성은 세균에서 자연적으로 발생할 수 있지만 항생제의 사용 및 오용이 증가함에 따라 크게 악화되고 있다. 문제를 추가하는 것은 항생제 내성 메커니즘의 다양성이다; 다양한 이질적 유전자가 내성을 부여할 수 있고, 관련이 없는 세균이 항생제 내성 유전자를 수평으로 전달할 수 있다. 또한 WHO는 "일부 새로운 항생제가 개발되고 있지만, 이들 중 어느 것도 항생제 내성균의 가장 위험한 형태에 효과가 있을 것으로 예상되지 않는다(같은 글)"고 명시하였다.

따라서, 항생제 내성을 감소시키는 새로운 방법이 개발되어 이용 가능하여야 함은 반드시 필수적이다.

본 발명은 세균 조성물이 대상체의 위장 (GI) 마이크로바이옴에서 항생제 내성 유전자의 존재비를 감소시키기 위해 사용될 수 있다는 발견에 관한 것이다.

본 발명은 대상체의 마이크로바이옴에서 하나 이상의 항생제 내성 유전자의 존재비를 감소시키는 데 사용하기 위한 포자 형성자 세균을 포함하는 치료적 유효량의 마이크로바이옴 조성물을 포함하는 조성물을 제공한다.

본 발명은 또한 바람직하지 않은 수준 또는 집단의 약물 내성 세균을 가질 위험이 있거나 가진 것으로 진단된 대상체를 치료하기 위해 하나 이상의 건강한 인간 개체로부터 유래된 후벽균(Firmicutes)을 포함하는 치료적 유효량의 마이크로바이옴 조성물을 포함하는 조성물을 제공한다.

본 발명은 또한 대상체의 마이크로바이옴에서 항생제 내성 세균의 존재비를 감소시키는 용도를 위한 ROAR 조성물을 제공한다.

본 발명은 추가로 선택적으로 체액 또는 노폐물과의 접촉을 포함하는, 직접 또는 간접적으로 접촉할 가능성이 큰 적어도 2명의 개체에 대한 투여를 통해, 항생제 내성 유전자의 전달 주기를 방해하는 용도를 위한 ROAR 조성물을 제공한다.

또한, 본 발명은 대상체의 마이크로바이옴의 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는 방법을 제공하며, 상기 방법은 포자-형성자 세균을 함유하는 치료적 유효량의 마이크로바이옴 조성물을 투여하는 것을 포함한다.

본 발명은 또한 바람직하지 않은 수준 또는 집단의 약물 내성 세균을 가질 위험이 있거나 가진 것으로 진단된 대상체를 치료하는 방법을 제공하며, 상기 방법은 하나 이상의 건강한 인간 개체로부터 유래된 후벽균을 함유하는 치료적 유효량의 마이크로바이옴 조성물을 투여하는 것을 포함한다.

본 발명은 추가로 대상체의 마이크로바이옴의 항생제 내성균의 존재비를 감소시키는 방법을 제공하며, 상기 방법은 치료적 유효량의 ROAR 조성물을 투여하는 단계를 포함한다.

본 발명은 또한 항생제 내성 유전자의 전달 주기를 방해하는 방법을 제공하며, 상기 방법은 체액 또는 노폐물과의 접촉을 포함하여 직접 또는 간접적으로 접촉할 가능성이 큰 적어도 2 명의 개체에게 ROAR 조성물을 투여하는 단계를 포함한다.

상기 언급된 임의의 방법의 다양한 양태는 하기에 제시된 바와 같다.

일부 양태에서, 항생제 내성 유전자(들)는 표 1에 열거된 것들로부터 선택된다.

일부 양태에서, 표 1의 적어도 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 초과의 항생제 내성 유전자의 존재비가 감소된다.

일부 양태에서, 약물 또는 항생제는 표 2에 열거된 약물 종류로부터 유래된다.

일부 양태에서, 방법은 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25개 또는 그 초과의 항생제 내성 유전자 또는 약물 종류의 존재비를 감소시키는 단계를 포함하거나 또는 감소시키는 추가적인 결과를 초래하는 용도를 위한 조성물을 추가로 포함한다.

일부 양태에서, 조성물은 표 3에 열거된 하나 이상의 종을 포함한다. 일부 양태에서, 표 3에 열거된 종은 또한 표 4에 열거되지 않는다. 조성물은 상기 또는 본원의 다른 곳에 기재된 방법에 의해 투여될 수 있다.

일부 양태에서, 조성물은 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함한다. 일부 양태에서, 표 3에 열거된 종은 또한 표 4에 열거되지 않는다. 조성물은 상기 또는 본원의 다른 곳에 기재된 방법에 의해 투여될 수 있다.

일부 양태에서, 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함한다. 종은 상기 또는 본원의 다른 곳에 기재된 방법에 의해 투여될 수 있다.

일부 양태에서, 조성물은 표 4의 하나 이상의 종을 포함하지 않는다. 일부 양태에서, 포함되지 않은 표 4에 열거된 종은 표 3에 열거되지 않는다. 상기 조성물은 상기 또는 본원의 다른 곳에 기재된 방법에 의해 투여될 수 있다.

일부 양태에서, 상기 종은 표 6에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하지 않는다. 종은 상기 또는 본원의 다른 곳에 기재된 방법에 의해 투여될 수 있다.

일부 양태에서 조성물 중 세균은 포자의 형태이다.

일부 양태에서, 조성물 중 세균은 배양된다.

일부 양태에서, 조성물은 후벽군 및 하나 이상의 박테로이데스(Bacteroides) 종을 포함한다.

일부 양태에서, 대상체는 퀴놀론 내성, 베타-락탐-내성 및 카바페넴-내성 세균으로 이루어진 군으로부터 선택된 1, 2 또는 3개의 세균의 감소된 존재비를 가진다.

일부 양태에서, 대상체는 항생제 치료에 비반응성이었다.

일부 양태에서, 대상체는 C. 디피실리(C.difficile) 감염 또는 질환, 또는 대장염을 앓고 있거나 발병할 위험이 있으며, 일부 양태에서, 대장염은 선택적으로 크론병 또는 궤양성 대장염 (예를 들어, 경증 내지 중등도의 궤양성 대장염)이다. 일부 양태에서, 대상체는 C. 디피실리 감염 또는 질환, 또는 대장염 (예를 들어 크론병 또는 궤양성 대장염, 예를 들어, 경증 내지 중등도의 궤양성 대장염)을 갖지 않는다 (또는 발병 위험이 없다).

본 발명은 또한 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비 감소와 관련된 세균 종을 포함하는 조성물을 제공한다.

일부 양태에서, 항생제 내성 유전자(들)는 표 1에 열거된 것들로부터 선택된다.

일부 양태에서, 표 1의 적어도 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 초과의 항생제 내성 유전자의 존재비가 감소된다.

일부 양태에서, 항생제는 표 2에 열거된 종류로부터 유래된다.

일부 양태에서, 조성물은 표 3에 열거된 하나 이상의 종을 포함한다. 일부 양태에서, 표 3에 열거된 종은 또한 표 4에 열거되지 않는다.

일부 양태에서, 조성물은 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함한다. 일부 양태에서, 표 3에 열거된 종은 또한 표 4에 열거되지 않는다.

일부 양태에서, 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함한다.

일부 양태에서, 조성물은 표 4의 하나 이상의 종을 포함하지 않는다. 일부 양태에서, 포함되지 않은 표 4의 종은 표 3에 열거되지 않는다.

일부 양태에서, 종은 표 6에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하지 않는다.

일부 양태에서, 조성물은 하나 이상의 후벽군 종을 포함한다.

일부 양태에서, 조성물은 하나 이상의 박테로이데스 종을 포함한다.

일부 양태에서, 조성물 중 세균은 포자의 형태이다.

일부 양태에서, 조성물 중 세균은 건강한 대상체의 배설물(feces)로부터 유래된 포자 분획으로부터 수득된다.

일부 양태에서, 조성물은 하나 이상의 후벽군 종, 및 선택적으로 하나 이상의 박테로이데스 종을 조성물 중의 유일한 세균 종으로서 포함한다.

일부 양태에서, 조성물 중 세균은 배양된다.

본 발명은 또한 조성물이 투여되는 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는 용도를 위한 세균을 포함하는 조성물을 제공한다.

일부 양태에서, 조성물 중 세균은 건강한 대상체의 배설물로부터 유래된 포자 분획으로부터 수득된다.

일부 양태에서, 세균은 대상체에서 하나 이상의 항생제 내성 유전자의 존재비 감소와 관련되도록 선택된다.

일부 양태에서, 항생제 내성 유전자(들)는 표 1로부터 선택된다.

일부 양태에서, 조성물은 표 3으로부터 선택된 적어도 하나의 종을 포함한다.

일부 양태에서, 조성물은 표 4의 종을 포함하지 않는다.

본 발명은 또한 조성물이 투여되는 대상체에서 하나 이상의 항생제 내성 유전자의 존재비를 감소시키는 데 유용한 세균 조성물을 확인하는 방법을 제공하며, 상기 방법은 표 3의 하나 이상의 세균 종의 존재에 대해 조성물을 스크리닝하는 단계를 포함하고, 여기서 세균 조성물에서 표 3의 하나 이상의 종의 검출은 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는데 사용될 수 있는 조성물의 확인을 나타낸다. 일부 양태에서, 표 3의 종은 또한 표 4에 열거되지 않는다.

일부 양태에서, 스크리닝은 조성물 중 표 5의 하나 이상의 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열의 검출을 포함한다.

일부 양태에서, 방법은 표 4의 하나 이상의 세균 종의 존재에 대한 스크리닝을 추가로 포함한다. 일부 양태에서, 표 4로부터 스크리닝된 종은 또한 표 3에 열거되지 않는다.

일부 양태에서, 스크리닝은 조성물 중 표 6의 하나 이상의 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열의 검출을 포함한다.

본 발명은 또한 치료 방법에 사용하기 위한 배설물의 공여자를 스크리닝하는 방법을 포함하며, 상기 방법은 표 3 또는 표 4의 세균 종의 존재에 대해 잠재적 공여자로부터의 배설물 샘플을 시험하는 단계를 포함하며, 여기서 표 3으로부터 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 될 수 있음을 나타내는 반면, 표 4로부터 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 되지 않아야 함을 나타낸다. 일부 양태에서, 시험된 표 3으로부터의 종은 표 4에 열거되지 않는다. 일부 양태에서, 시험된 표 4로부터의 종은 표 3에 열거되지 않는다.

본 발명은 대상체가 ROAR 조성물로 치료함으로써 이익을 얻을 수 있는지를 결정하는 방법을 추가로 포함하며, 상기 방법은 대상체로부터의 샘플이 표 4로부터의 하나 이상의 세균 종을 포함하는지를 결정하는 것을 포함하며, 여기서 표 4로부터 하나 이상의 종의 검출은 대상체가 ROAR 조성물을 사용하는 치료로부터 이익을 얻을 수 있다는 것을 나타낸다. 일부 양태에서, 시험된 표 3으로부터의 종은 표 4에 열거되지 않는다. 일부 양태에서, 시험된 표 4로부터의 종은 표 3에 열거되지 않는다.

본 발명은 조성물 (예를 들어, 상기 및 본원의 다른 곳에 기술된 조성물)을 추가로 제공하며, 여기서 조성물 중 세균은 항생제 내성의 동물 모델에서 하나 이상의 항생제 내성 유전자(들)의 존재비를 감소시키는 능력을 나타낸다. 일부 양태에서, 동물 모델은 하나 이상의 항생제로 처리된 후 하나 이상의 항생제 내성 유전자를 보유하는 하나 이상의 세균으로 콜로니화시킨 마우스이다. 일부 양태에서, 마우스는 반코마이신 내성 세균 또는 반코마이신 및 카바페넴 내성 세균으로 콜로니화된다.

본 발명은 또한 본원에 기술된 방법에서 특정된 목적을 위해 본원에 기술된 조성물의 용도, 뿐만 아니라 이들 용도를 위한 약제의 제조를 위한 이들 조성물의 용도를 포함한다.

본원에 언급된 각각의 특허 문헌 및 과학 논문, 및 그에 인용된 특허 문헌 및 과학 논문의 전체 개시는, 모든 목적을 위해 본원에 참고로 명백하게 포함된다.

본 발명의 추가 특징 및 장점은 하기에 보다 구체적으로 설명된다.

도 1은 인간 공생 포자 조성물을 투여한 후 7, 28 및 56일에 인간 대상체에서 플루오로퀴놀론 내성과 관련된 유전자의 감소를 검출한 실험 결과를 도시한 그래프이다. 백색 = 위약을 받은 대상체, 중간 회색 = 포자 조성물로 처리된 모든 대상체, 및 어두운 회색 = 유의한 생착 신호를 갖는 대상체의 서브셋으로부터의 결과.
도 2는 인간 공생 포자 조성물을 투여한 후 7, 28 및 56일에 인간 대상체에서 베타-락탐 항생제 내성과 관련된 유전자의 감소를 검출한 실험 결과를 도시한 그래프이다. 백색 = 위약을 받은 대상체, 중간 회색 = 포자 조성물로 처리된 모든 대상체, 어두운 회색 = 유의한 생착 신호를 갖는 대상체의 서브셋으로부터의 결과.
도 3은 코호트 (A: 위약, B: 건강한, 스크리닝된 사람의 대변으로부터 제조된 포자, 매주, D: 반코마이신. 매주 포자 제조, 및 C: 반코마이신, 매일 포자 제조에 의해 패싯화된, 시점 (x 축)에 따라 항생제 내성 유전자의 존재비를 나타내는 그래프이다.
도 4는 빠른 초기 생착을 나타내지 않은 대상체에 비해, 중재군(Arm) D (반코마이신, 매주 포자 제조)에서 포자 제조물에 의해 빠른 초기 생착이 있는 대상체에서 항생제 내성 유전자가 더 빠르게 감소함을 보여주는 그래프이다. 방문 4 (8일)는 항생제 중단 직후이며, 방문 4 (11 일)는 첫 포자 제조 시점이다.

항생제 내성 (본원에서 "AbxR"으로 지칭함)은 증가하는 전 세계 공중 보건 문제이다. 모든 종류의 항생제에 대한 내성은 전 세계의 모든 지역에서 보고되었으며 (2014, Antimicrobial Resistance, Global Report on Surveillance, Summary, WHO) 기존 항생제의 개발은 수요에 비해 상대적으로 느리다. 예를 들어, 1980년대에 리포펩티드 항생제 답토마이신이 발견 이후에 새로운 종류의 항생제는 시판되지 않았다. 또한 항생제 사용을 제한하는 항생제 관리 프로그램은 내성 증가 추세를 즉시 반전시키지 않는다.

출원인은 세균, 예를 들어 건강한 인간으로부터 유래된 포자 형성자 세균을 포함하는 조성물로 대상체를 치료하는 것이 인간 대상체에서 AbxR 유전자 (총괄적으로, "장내 레지스톰")의 존재비를 감소시킬 수 있음을 발견하였다. 이러한 조성물은 본원에서 항생제 내성 감소 조성물 (ROAR:reduction of antibiotic resistance 조성물)로 지칭된다.

또한, 이러한 치료는 여러 종류의 항생제, 예를 들어, β-락탐 (카바페넴 포함), 퀴놀론, 당펩티드 (예를 들어 반코마이신), 및 테트라사이클린에 대한 내성과 연관된 AbxR 유전자의 존재비를 줄일 수 있다. 또한, 비병원성 공생체는 항생제 내성 유전자를 보유할 수 있으며, 치료는 비병원성 공생 유기체에서 항생제 내성 유전자의 존재비를 감소를 초래하는 것으로 밝혀졌다. 특정 이론을 고수하지 않으면서, 이들 데이터는 비병원성 공생 유기체로부터 병원성 세균으로 항생제 내성 유전자의 수평 이동을 감소시키는 메커니즘에 의해 적어도 부분적으로, 항생제 내성 유전자의 존재를 감소시키는 방법을 지지한다. 이러한 메카니즘은 이들 세균을 영양소에 대한 경쟁에서 우월하게 함으로써 항생제 내성 유전자를 보유하는 세균의 존재비를 감소시키는 것과; AbxR 유전자를 보유하는 잠재적 병원체의 성장을 제한하는 숙주에서의 반응을 유도함으로써 항생제 내성 유전자를 보유하는 세균의 존재비를 감소시키는 것과; AbxR 유전자를 보유한 잠재적 병원체에 직접 길항성인 세균을 도입함으로써 항생제 내성 유전자를 보유하는 세균의 존재비를 감소시키는 것과; 기회 병원체를 감소시키고/시키거나, 항생제 내성 및 감수성 유기체 사이에서 항생제 내성 유전자의 확산 가능성을 감소시키는 것과 적어도 부분적으로 관련될 수 있다. 일부 양태에서, 항생제 내성 유전자의 존재의 감소는 AbxR 유전자를 보유하는 미생물 숙주에서 콜로니화를 감소시킴으로써 발생한다.

일부 양태에서, ROAR 조성물은 항생제 내성 전달 주기를 파괴하거나 예방하기 위해 사용된다. 이러한 방법에서, ROAR 조성물은 항생제 내성 주기의 위험이 있는 환경 또는 항생제 내성 주기의 존재가 확인된 환경, 예를 들어 항생제 내성이 퍼지는 것으로 확인되었거나 그러한 퍼질 위험이 있는 환경에 진입하는 대상체에게 투여될 수 있다. 이러한 환경의 예시로는 병원, 중환자실, 요양원, 재활 센터, 그룹 홈 등을 포함한다. 일부 양태에서, 이러한 환경에서의 투여는 만성적이다. 일부 양태에서, 대상체는 하나 이상의 AbxR 유전자에 의한 콜로니화를 예방 또는 감소시키도록 처리된다. 하나 이상의 AbxR 유전자를 보유하는 대상체에서, 대상체가 C. 디피실리 질환의 치료 후 이러한 대상체가 항생제 내성 세균에 감염되거나 보유할 수 있기 때문에, 대상체에서 AbxR 감염의 위험을 감소시키고, AbxR 유전자를 전달할 위험을 감소시키는 조성물이 투여될 수 있다. 일부 양태에서, 조성물은 AbxR 유전자의 확산과 관련된 특정 위험이 있는 환경에서 작업자에게 투여된다.

일부 환경에서는 예를 들어 병원 (특히 중환자실) 및 요양원에서 환자의 "선택적 오염 제거"가 권장되었다 (예를 들어, Silvestri and van Saene, "Selective decontamination of the digestive tract: an update of the evidence," HSR Proc. Intensive Care Cardiovasc. Anesth. 4:21-29, 2012; Oostdijk et al., "Selective decontamination in European intensive care patients," Intensive Care Med. 38:533-538, 2012 참조). ROAR 조성물은 이들 및 다른 환경에서 항생제 내성 유전자의 존재를 감소시키기 위해 이용 가능한 방법의 설비에 더하여, 이러한 선택적 오염 제거에 유용한 대안 또는 보충일 수 있다.

ROAR 조성물

ROAR 조성물은 일반적으로 후벽군을 포함한다. 일부 양태에서, 후벽군은 포자를 형성할 수 있다 (포자 형성자). 조성물 중 세균은 포자 형태, 혼합 식물성 및 포자 형태, 또는 식물성 형태일 수 있다. 일부 경우에, 조성물은 후벽군으로 이루어진다. 일부 양태에서, ROAR 조성물은 하나 이상의 종의 박테로이데테스(Bacteroidetes)를 포함한다. 일부 양태에서, ROAR 조성물은 각각의 후벽군 및 박테로이데테스로부터의 하나 이상의 종으로 구성된다. 조성물의 단독 세균 종으로서 후벽균 (또는 후벽균 및 박테로이데테스)을 포함하는 또는 이루어지는 조성물은 자연 발생되지 않는다.

비제한적인 예시로서, ROAR 조성물은 대변, 예를 들어 인간 대변으로부터 단리된 세균으로부터 제조될 수 있다. 일반적으로, 대변은 치료될 동물과 동일한 종의 건강한 동물 (예를 들어, 인간)로부터 유래된다. 세균은, 예를 들어, 대변에 존재하는 임의의 비-포자형 세균을 사멸시키기에 적합한 양의 에탄올을 사용하는 방법으로 제조될 수 있다. 이러한 제조의 예시는 예를 들어 WO 2014/121302에서 찾을 수 있다.

일부 양태에서, ROAR 조성물은 대상체에서 항생제 내성 유전자의 존재비 감소와 관련된 선택된 세균 종을 포함하거나 이로 구성된다 (예를 들어, 하기 표 3 참조). 이러한 조성물은 본원에서 "설계된 Abx 조성물"로 지칭된다. 설계된 조성물에서 종의 수 (예를 들어, 표 3으로부터)는 예를 들어 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 또는 그 초과일 수 있다. 일부 양태에서, 종의 수는 적어도 하나 및 50 이하, 예를 들어 45 미만, 40 미만, 35 미만, 30 미만, 25 미만, 20 미만, 15 미만, 10 미만, 또는 5 미만일 수 있다. 일부 양태에서, 표 3으로부터 선택된 종은 표 4에 또한 열거된 종을 포함하지 않는다.

설계된 ROAR 조성물에서 개별 종을 별도로 배양한 다음 조합하여 조성물을 생성할 수 있다. 일부 양태에서, ROAR 조성물은 조성물의 전부 또는 서브셋을 공-배양한 후 공배양되지 않은 성분을 조합하여 조성물을 생성함으로써 생산된다. 일부 양태에서, ROAR 조성물은 건강한 인간의 배설물로부터 유래된 포자 분획을 배양함으로써 생산된다. 생성된 배양물은 ROAR 조성물로서 사용될 수 있다.

일부 양태에서, ROAR 조성물에 포함시키기 위해 선택된 종은 특정 종류의 항생제 내성 유전자, 예를 들어 퀴놀론, 베타-락탐, 및/또는 카바페넴의 존재비의 감소에 대한 내성과 관련된 유전자와 관련이 있다 (또한 표 2 참조). 예를 들어, 상기 기재된 조성물의 특정 예에서, ROAR 조성물 (예를 들어, 설계된 Abx 조성물) 중 세균 종은 표 2로부터 선택되고, 선택적으로는 16S rDNA 서열 (또는 이의 단편, 예를 들어, 16S rDNA V4 및/또는 V6 영역을 포함하는 단편; 또한 예시적 서열에 대해서는 하기 및 표 5 참조)의 분석에 의해 확인될 것이다.

일부 양태에서, ROAR 조성물에 유용한 종은 기준 종, 예를 들어 표 3에서 확인된 종의 16S rDNA에 대해 적어도 95%의 서열 동일성 ("동일성") (예를 들어, 적어도 96%, 97%, 98% 또는 99%, 또는 100%)을 갖는 전장 16S rDNA를 갖는 종이다 (예를 들어, 서열 정보는 표 5 참조). 일부 양태에서, ROAR 조성물에 유용한 종은 기준 종, 예를 들어 표 3의 종의 16S rDNA에 대해 적어도 97% 서열 동일성 ("동일성")을 갖는 전장 16S rDNA를 갖는 종이다 (예를 들어, 서열 정보는 표 5를 참조). 일부 양태에서, 유용한 종은 기준 종, 예를 들어 표 3에서 확인된 종의 16S rDNA 서열의 V4 및/또는 V6 영역에 대해 적어도 95% 동일성 (예를 들어, 적어도 96%, 97%, 98%, 또는 99%, 또는 100%)을 갖는 V4 및/또는 V6 영역 16S rDNA 서열을 가진다 (예를 들어, 서열 정보는 표 5 참조). 일부 양태에서, 유용한 종은 기준 종, 예를 들어 표 3에서 확인된 종의 16S rDNA 서열의 V4 및/또는 V6 영역에 대해 적어도 97% 동일성을 갖는 V4 및/또는 V6 영역 16S rDNA 서열을 가진다 (예를 들어, 서열 정보는 표 5를 참조). 일부 양태에서, 유용한 종은 기준 종, 예를 들어 표 3에서 확인된 종의 전장 게놈 DNA에 대해 적어도 95% 동일성 (예를 들어, 적어도 96%, 97%, 98%, 또는 99%, 또는 100%)을 갖는 게놈 서열을 가진다. 일부 양태에서, 유용한 종은 기준 종, 예를 들어 표 3에서 확인된 종의 전장 게놈 서열에 대해 97% 동일성을 갖는 게놈 서열을 가진다. 서열, 예를 들어 16S rDNA, V4 또는 V6 서열이 본원에 제공되지 않는 경우, 이러한 서열을 확인하기 위한 방법은 당업계에 널리 공지되어 있다. 표 5는 기준 서열로서 사용될 수 있는 전장 16S rDNA 서열의 비제한적 예시를 제공한다. 일반적으로, 기준 종과의 동일성 또는 동일성 백분율은 유기체에서 발견된 하나 이상의 16S rDNA 서열 (또는 단편, 예를 들어 V4 및/또는 V6)과의 동일성 또는 동일성 백분율을 의미한다.

일부 경우에, 본 발명에 유용한 세균 종, 예를 들어 본원에 개시된 종의 균주는 ATCC (atcc.org), DSMZ (dsmz.de), 또는 리켄 생물자원 센터 (en.brc.riken.jp)와 같은 공공 생물학적 자원 센터로부터 얻을 수 있다. 본 발명의 종 또는 다른 측면을 확인하는데 유용한 16s rDNA 서열은 공개 데이터베이스, 예를 들어 인간 마이크로바이옴 프로젝트 (HMP) 웹 사이트 또는 GenBank로부터 얻을 수 있다.

서열 동일성을 판단하는 방법은 당업계에 공지되어 있으며 예시는 아래에 제공된다.

일부 양태에서, ROAR 조성물에서 배제된 종은 특정 종류의 항생제 내성 유전자의 존재와 양의 상관관계가 있는 종이다 (예를 들어, 표 4 참조). 이들 종은 상기 기재된 것과 같은 방법을 사용하여 확인될 수 있다 (또한 상응하는 서열 정보는 표 6 참조).

이들 예시에서 "으로 이루어진(consisting of)"은 조성물에 존재하는 세균 유형을 지칭하는 것으로 이해되어야 한다. 그러므로 열거된 종으로 "~으로 이루어진" 세균 제제는 하나 이상의 부형제 (예를 들어, 하나 이상의 캡슐 포함), 수성 또는 비수성 매질 (예를 들어, 글리세롤, 폴리에틸렌 글리콜, 코코아 버터, 물 및/또는 완충제), 및/또는 하나 이상의 프리바이오틱스 또는 소분자 약물과 같은 추가의 비세균성 물질을 함유할 수 있다.

종/명명 정보

세균의 이름 및 분류는 문헌에 반영되지 않을 수 있는 변경에 따라 달라질 수 있다. 편의상, 일부 세균 종에 대한 대체 명칭이 본원에 제공될 수 있지만 포괄적인 대안 명칭 세트가 되도록 의도되지는 않는다. 일부 양태에서, 종은 16S rDNA 서열의 전부 또는 일부 (예를 들어, V4 또는 V6 영역)의 서열 동일성, 예를 들어 적어도 90%, 93% 95%, 96%, 97%, 98%, 99%, 또는 100% 동일성으로 확인된다.

동일성의 결정

일부 양태에서, 클레이드, 작동 분류학적 단위 (OTU), 종 및 균주는 이들의 16S rDNA 서열에 의해 식별된다. 클레이드, OTU, 종 및 균주의 관련성은 클레이드, OTU, 종 또는 균주 간의 동일성 백분율에 의해 결정될 수 있다. 기준 서열과 질의 서열(query sequence) 사이의 동일성 백분율은 당업계에 공지된 방법을 사용하여 결정될 수 있다. 이러한 결정을 위한 방법의 비제한적인 예시가 아래에 제공된다. 본원에 사용된 바와 같이, 2개의 뉴클레오티드 서열 사이의 관련성은 파라미터 "동일성"에 의해 기술된다.

한 양태에서, 질의 서열과 참조 서열 사이의 서열 동일성의 정도는 (1) 디폴트 스코어링 매트릭스 및 디폴트 갭 페널티를 사용하여 임의의 적절한 정렬 프로그램에 의해 2개의 서열을 정렬하고, (2) 정확한 일치 수를 식별하고, 여기서 정확한 일치는 정렬 프로그램이 정렬에서 주어진 위치에 있는 2개의 정렬된 서열에서 동일한 뉴클레오티드를 확인한 것이며, 그리고 (3) 정확한 일치의 수를 참조 서열의 길이로 나눔으로써 결정된다.

또 다른 양태에서, 질의 서열과 참조 서열 사이의 서열 동일성 정도는 (1) 디폴트 스코어링 매트릭스 및 디폴트 갭 페널티를 사용하여 임의의 적절한 정렬 프로그램에 의해 2개의 서열을 정렬하고, (2) 정확한 일치 수를 식별하고, 여기서 정확한 일치는 정렬 프로그램이 정렬에서 주어진 위치에 있는 2개의 정렬된 서열에서 동일한 뉴클레오티드를 확인한 것이며, 그리고 (3) 정확한 일치의 수를 2개의 서열 중 가장 긴 길이로 나눔으로써 결정된다.

또 다른 양태에서, 질의 서열과 참조 서열 사이의 서열 동일성의 정도는 (1) 디폴트 스코어링 매트릭스 및 디폴트 갭 페널티를 사용하여 임의의 적절한 정렬 프로그램에 의해 2개의 서열을 정렬하고, (2) 정확한 일치 수를 식별하고, 여기서 정확한 일치는 정렬 프로그램이 정렬에서 주어진 위치에 있는 2개의 정렬된 서열에서 동일한 아미노산 또는 뉴클레오티드를 확인한 위치이며, 그리고 (3) 정확한 일치 수를 "정렬 길이"로 나눔으로써 결정되고, 정렬 길이는 갭 및 서열의 돌출 부분을 포함하는 전체 정렬의 길이이다.

서열 동일성 비교는 일반적으로 서열 비교 프로그램의 도움으로 수행된다. 이러한 상업적으로 또는 공개적으로 이용 가능한 컴퓨터 프로그램은 복잡한 비교 알고리즘을 사용하여 둘 이상의 서열 사이의 차이를 초래할 수 있는 진화 사건을 가장 잘 반영하는 둘 이상의 서열을 정렬시킨다. 따라서, 이들 알고리즘은 동일하거나 유사한 아미노산의 정렬을 보상하고 갭의 삽입, 갭 연장 및 비-유사 아미노산의 정렬을 페널티를 주는 스코어링 시스템으로 작동한다. 비교 알고리즘의 스코어링 시스템은 하기를 포함한다:

i) 갭이 삽입될 때마다 페널티 스코어 할당 (갭 페널티 스코어)

ii) 기존 갭이 추가 포지션으로 연장될 때마다 페널티 스코어 할당 (연장 페널티 스코어)

iii) 동일한 아미노산의 정렬시 높은 점수의 할당, 및

iv) 동일하지 않은 아미노산의 정렬시 가변 점수의 할당.

일반적으로, 정렬 프로그램의 디폴트 값은 서열 비교에 사용된다. 동일성을 결정하는데 유용한 적합한 컴퓨터 프로그램은 예를 들어 BLAST (blast.ncbi.nlm.nih.gov)를 포함한다.

본 발명의 한 양태에서, 정렬 프로그램은 선택된 서열의 전장, 예를 들어 전장, V4 또는 V6 16S rDNA 서열에 대한 정렬을 최적화한다. 예를 들어, 전체 정렬 프로그램은 니들만 브니쉬 (Needleman-Wunsch) 알고리즘 (Needleman and Wunsch, J. Mol. Biol. 48: 443-453, 1970)을 기반으로 한다. 이러한 프로그램의 비제한적인 예시는 ebi.ac.uk/Tools/psa/에서 사용 가능한 EMBOSS 니들 및 EMBOSS 스트레쳐 프로그램이다.

한 양태에서, 서열은 전체 정렬 프로그램에 의해 정렬되고, 서열 동일성은 프로그램에 의해 식별된 정확한 일치의 수를 "정렬 길이"로 나눈 값을 식별함으로써 계산되며, 여기서 정렬 길이는 서열의 갭과 돌출 부분을 포함하는 전체 정렬의 길이이다. 다른 실시예에서, 전체 정렬 프로그램은 니들만 브니쉬 알고리즘을 사용하고, 서열 식별은 프로그램에 의해 식별된 정확한 일치의 수를 "정렬 길이"로 나눈 값을 식별함으로써 계산되며, 여기서 정렬 길이는 서열의 갭 및 돌출 부분을 포함하는 정렬 전체의 길이이다.

또 다른 양태에서, 전체 정렬 프로그램은 EMBOSS 니들 및 EMBOSS 스트레쳐로 구성된 군으로부터 선택되고, 서열 식별은 프로그램에 의해 식별된 정확한 일치의 수를 "정렬 길이"로 나눈 값을 식별함으로써 계산되며, 여기서 정렬 길이는 갭 및 서열의 돌출 부분을 포함하는 전체 정렬의 길이이다.

소프트웨어가 정렬을 생성하면, 유사성 백분율(%)과 서열 동일성 백분율(%)을 계산할 수 있다.

AbxR 활성 또는 AbxR 유전자의 존재에 대해 조성물을 시험하는 방법

ROAR 조성물은 당 업계에 공지된 시험관 내 및/또는 생체 내 모델을 이용하여 동물의 위장관에서 항생제 내성 유전자의 존재비를 감소시키는 능력에 대해 시험될 수 있다 (예를 들어, Schjørring and Krogfelt, Int. J. Microbiol. 2011:312956, 2011; Marra, "Animal models in drug development for MRSA," Meth. Mol. Biol. 1085:333-345, 2014 참조). 이러한 모델은 후보 ROAR 조성물을 시험하는 데 사용하기에 적합할 수 있다. 적합한 모델의 추가 예시는 실시예에 기재되어 있다. 또한, ROAR 조성물은 임상 시험에 등록된 인간 대상체에서 AbxR 유전자의 존재비를 감소시키는 능력에 대해 시험될 수 있다.

대상체

일부 양태에서, 본원에 개시된 조성물 (ROAR 조성물)을 사용하여 치료하기에 적합한 대상체는 예를 들어 위장(GI) 관의 적어도 일부에서, 바람직하지 않은 수준의 AbxR 미생물을 가질 위험이 있거나 진단된 동물, 예를 들어, 포유류, 예를 들어, 인간, 개, 고양이, 소, 양과, 염소, 말, 또는 다른 농장, 가축 또는 동물원 동물이다. 바람직하지 않은 수준의 AbxR 유기체는 예를 들어, 인간을 치료하는 맥락에서, 건강한 집단, 인간 마이크로바이옴 프로젝트 데이터베이스에 기록된 건강한 집단에서의 것보다 상당히 높은 수준으로 식별될 수 있다. 이러한 유기체는, 예를 들어, 대상체로부터 대변 또는 다른 위장 샘플을 배양하고 항생제 내성의 존재에 대한 공지된 시험 방법을 사용하여 검출될 수 있다. 방법은 예를 들어, 희석 방법 (배지 한천 희석법), 디스크-확산법, E-테스트, 자동화 방법, 베타-락타마제 검출 시험 및 발색 세팔로스포린 시험과 같은 메커니즘 특정 시험, PCR 및 DNA 혼성화법과 같은 유전자형 분석법을 포함한다. 이러한 방법은 또한 전체 범유전체학 샷건 (whole metagenomics shotgun, WMS) 시퀀싱에 의한 항생제 내성 관련 유전자의 확인 및 정량을 포함한다. 일부 양태에서, AbxR 유기체 또는 유전자의 바람직하지 않은 수준은 AbxR의 표현형과 관련된 유전자, 유전자 카세트 또는 유전자 마커의 존재 또는 부재를 확인하는 분자생물학적 방법을 사용하여 식별될 수 있다. 이러한 분자생물학적 방법의 일부 예시는 DNA 시퀀싱, 전사 프로파일링 및 분자 프로브를 이용하는 방법을 포함하지만 이에 제한되지 않는다.

일부 양태에서, ROAR 조성물로 치료하기에 적합한 대상체는 하나 이상의 항생제로의 치료에 반응하거나 반응하지 않았으며, 항생제 내성 미생물 집단의 존재가 유추된다.

일부 양태에서, ROAR 조성물로 치료하기에 적합한 대상체는 C. 디피실리 감염 또는 질환이 있거나 발병할 위험이 있다. 일부 양태에서, ROAR 조성물로 치료하기에 적합한 대상체는 대장염 (예를 들어, 크론병 또는 궤양성 대장염 (예를 들어, 경증 내지 중등도의 궤양성 대장염))을 갖거나 발병할 위험이 있다.

이점

대상체의 마이크로바이옴에 의한 항생제 내성의 존재 또는 발달 가능성에 더하여, 종래의 항생제의 사용은 예를 들어 장내 세균 불균형, 병원체의 과다 증식, 신경계 손상 및 알레르기 반응과 같은 GI 효과를 포함하는 심각한 부작용을 유발할 수 있다. ROAR 조성물은 전형적으로 공생 세균을 포함하고 예를 들어 치료를 받는 대상체에 의해 내약성이 우수한, 제한된 부작용을 가진다. ROAR 조성물은 필요에 따라, 시간이 지남에 따라 반복적으로 투여될 수 있고, 예를 들어, 치료된 개체에서 항생제 내성 유전자의 유병률을 감소시킴으로써, 다수의 항생제 군에 항생제 내성이 발생할 위험을 감소시킬 수 있다. 일반적으로, ROAR 조성물은 세균이 항생제 내성 유전자를 전달하는 전달주기를 조절할 수 있다. 이 특징은 예를 들어, 조성물의 사용이 취약한 환자가 개별적으로 및 환자 집단으로 둘 모두로서 항생제 내성에 노출되거나 항생제 내성에 걸릴 위험을 감소시키는 의료 환경에서 유용하다.

일부 양태에서, 조성물의 투여가 예를 들어, 국소 염증의 양을 감소시키고, GI 국소 미생물에 의한 전위 및 감염의 위험을 감소시킴으로써 상피 및 점막 장벽의 완전성을 개선시킬 수 있는 ROAR 조성물의 추가 이점이 있다.

정의

세균의 유형, 예를 들어 종의 "증강(augmentation)"은 존재비의 비모수적 시험에 의해 조성물에 존재하지 않는 종의 증가된 존재비의 처리 후 검출을 특징으로 하는 본 발명의 조성물로의 처리 효과이다.

세균의 유형, 예를 들어 종의 "생착(engraftment)"은 투여된 조성물로부터 종의 처리 후 검출을 특징으로 하는 본 발명의 조성물로의 처리 효과이며, 이는 처리된 대상체 전처리에서 검출되지 않는다. 검출 방법은 당업계에 공지되어 있다. 한 예시에서, 방법은 PCR에 대한 표준 파라미터를 사용하는 16S rDNA 서열의 PCR 검출이다.

"작동 분류학 단위(Operational taxonomic unit)", "OTU" (또는 복수, "OTUs")는 계통 발생 수의 말단 잎을 말하며 핵산 서열, 예를 들어 종의 수준에서 이러한 핵산 서열에 대해 서열 동일성을 공유하는 전체 게놈, 또는 특정 유전자 서열, 및 모든 서열에 의해 정의된다. 일부 양태에서 특정 유전자 서열은 16S 서열 또는 16S 서열의 일부, 예를 들어 가변 영역, 예를 들어, V4 영역이다. 다른 양태에서, 두 독립체의 전체 게놈을 시퀀싱하고 비교한다. 다른 양태에서, 다중 위치 서열 태그 (multilocus sequence tags, MLST), 특정 유전자 또는 유전자들의 집합과 같은 선택 영역을 일반적으로 비교한다. 16S 양태에서, 전체 16S 또는 16S 서열의 가변 영역에 걸쳐 ≥97% 평균 뉴클레오티드 동일성을 공유하는 OTU는 동일한 OTU로 간주된다 (예를 들어, Claesson et al.,　Nucleic Acids Res. 38:e200, 2010;　Konstantinidis et al.,　Philos. Trans. R. Soc. Lond. B. Biol. Sci. 361:1929-1940, 2006 참조). 완전한 게놈, MLSTs, 특정 유전자, 또는 유전자 세트를 포함하는 양태에서, ≥95% 평균 뉴클레오티드 동일성을 공유하는 OTU는 동일한 OTU로 간주된다 (예를 들어, Achtman and Wagner,　Nat. Rev. Microbiol. 6:431-440, 2008 참조). 일부 양태에서, 유기체 간의 서열을 비교함으로써 OTU를 구별할 수 있다. 일반적으로, 95% 미만의 서열 동일성을 갖는 서열은 동일한 OTU의 일부를 형성하는 것으로 간주되지 않는다. OTU는 또한 뉴클레오티드 마커 또는 유전자의 임의의 조합, 특히 고도로 보존된 유전자 (예를 들어, "하우스-키핑" 유전자), 또는 이들의 조합에 의해 특징지어질 수 있다. 이러한 특성화는 예를 들어 WGS 데이터 또는 전체 게놈 서열을 사용한다. 본원에 사용된 용어 "종(species)" 및 "OTU"는 문맥에 의해 달리 구별되지 않는 한 상호 교환적으로 사용된다.

본원에 기술된 조성물의 "치료적 유효량"은 개체의 질환 상태, 연령, 성별 및 체중과 같은 인자, 및 개체에서 원하는 반응, 예를 들어 하나 이상의 장애 파라미터의 완화, 또는 장애의 하나 이상의 증상의 완화 (및 선택적으로, 투여되는 임의의 추가 작용제의 효과)를 유도하는 조성물의 능력에 따라 달라질 수 있다. 치료적 유효량은 또한 조성물의 임의의 독성 또는 유해 효과가 치료학적으로 유리한 효과보다 더 큰 양이다. 본원에 기재된 바와 같은 조성물은 일반적으로 치료적 유효량으로 투여된다.

제제(formulation)

본원에 기재된 ROAR 조성물 (예를 들어, 설계된 Abx 조성물)은 당 업계에 공지된 방법을 사용하여 제조 및 투여될 수 있다. 임의의 적절한 방법이 사용될 수 있지만, 일반적으로, 조성물은 경구, 결장 내시경 또는 비위 전달용으로 제제화된다.

ROAR 제제는 이러한 제제의 제조 또는 전달에 적합한 하나 이상의 약제학적 부형제를 함유할 수 있다. 일부 양태에서, 제제는 액체 제제이다. 일부 양태에서, ROAR 조성물을 포함하는 제제는 하나 이상의 계면 활성제, 보조제, 완충제, 산화방지제, 등장성 조절제, 증점제, 점도 조절제 등을 포함할 수 있다.

일부 양태에서, 치료는 약제학적으로 허용가능한 담체를 포함하는 제제로 ROAR 조성물을 투여하는 것을 포함한다. 일부 양태에서, 부형제는 ROAR 조성물을 경구 투여 형태로 제공하기에 적합한 캡슐 또는 다른 형식을 포함한다. 부형제가 희석제로서 작용할 경우, 이는 활성 성분에 대한 비히클, 담체, 또는 매질로서 작용하는 고체, 반고체, 또는 액체 물질이 될 수 있다. 따라서, 제제는 정제, 환제, 산제, 로젠지제, 사쉐, 카세제, 엘릭시르제, 현탁제, 유제, 용액제, 시럽제, 연질 또는 경질 캡슐제, 좌제 또는 포장된 분말의 형태일 수 있다.

적합한 부형제의 일부 예시는 락토오스, 덱스트로스, 수크로스, 소르비톨, 만니톨, 전분, 검 아카시아, 인산칼슘, 알기네이트, 트라가칸트, 젤라틴, 칼슘 실리케이트, 미세결정질 셀룰로스, 폴리비닐피롤리돈, 셀룰로오스, 물, 시럽, 폴리에틸렌 글리콜, 글리세롤 및 메틸 셀룰로오스를 포함한다. 조성물은 당업계에 공지된 절차를 이용하여 환자에게 투여된 후 활성 성분을 빠르게, 지속하여, 또는 지연 방출로 제공하기 위해 제제화될 수 있다.

ROAR 조성물은 단위 투여 형태로 제제화될 수 있다. 일반적으로, 투여량은 약 10e2 내지 10e9 생존 가능한 콜로니 형성 단위 (cfu)를 포함한다. 일부 양태에서, ROAR 조성물은 포자 형태의 포자 형성 세균을 포함하거나 포자 형성 세균으로 구성된다. 이러한 경우에, 투여량은 "포자 CFU" 또는 "sCFU"로 결정될 수 있으며, 이는 전형적으로 플레이트 상에서 발아 및 성장에 의해 생존 가능한 포자의 수를 정량화한다.

용어 "단위 투약 형태"는 인간 대상체 및/또는 다른 포유동물에 대한 단위 투여량으로서 적합한 물리적 이산 단위를 지칭하며, 각 단위는 적합한 제약 부형제와 관련하여 원하는 치료 효과를 생성하도록 계산된 미리 결정된 양의 활성 물질을 함유한다. 투여량은 다수의 전달 비히클, 예를 들어 다수의 환제 또는 캡슐로 투여될 수 있다.

ROAR 조성물을 환자에게 투여하는 양 및 빈도는 투여되는 것, 투여의 목적, 예를 들어 예방 또는 치료, 환자의 상태, 투여 방식 등에 따라 달라질 것이다. 치료적 적용에서, 조성물은 질환의 하나 이상의 증상 또는 그의 합병증을 치료 또는 적어도 부분적으로 정지시키기에 충분한 양으로 질환을 앓고 있는 환자에게 투여될 수 있다. 유효 복용량은 질환이나 치료될 병태, 뿐만 아니라 담당 임상의의 판단에 의해, 질환의 중증도, 나이, 체중, 환자의 일반적인 상태 등과 같은 인자에 따라 다를 수 있다.

투여량은 예를 들어, 각각의 개별 종 또는 균주의 cfu의 총 수를 참조할 수 있거나, 투여량에서 미생물의 총 수를 참조할 수 있다. 당업계에서 투여량에서 유기체의 수를 결정하는 것은 정확하지 않으며 존재하는 유기체의 수를 결정하는데 사용된 방법에 의존할 수 있는 것으로 이해된다. 예를 들어, 조성물 중 포자의 수는 디피콜린산 분석을 사용하여 결정될 수 있다. 일부 경우에, 유기체의 수는 배양 분석을 사용하여 결정될 수 있다. 포자가 존재할 때, 배양 방법에 의존하는 분석의 능력은 포자의 효율적인 발아에 의존할 수 있다. 정량적 핵산-기반 방법은 비-생존 미생물로부터의 핵산이 충분히 감소 또는 제거되는지에 의존할 수 있다. 시험관 내 또는 동물 모델 시험 시스템으로부터 유도된 용량-반응 곡선으로부터 유효 복용량을 추정할 수 있다.

스크리닝 방법

본 발명은 또한 대상체에서 항생제 내성 유전자의 존재비를 감소시키기 위해 사용될 수 있는 세균 조성물을 확인하는 방법을 제공한다. 이들 방법에서, 후보 조성물은 표 3의 하나 이상의 세균 종의 존재에 대해 분석된다. 이들 종의 하나 이상의 검출 (예를 들어, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 또는 그 초과)은 조성물이 항생제 내성 유전자의 존재비를 감소시키는 데 유용할 수 있음을 나타낸다. 후보 조성물을 추가로 스크리닝하기 위해 추가 시험을 수행할 수 있다. 예를 들어, 후보 조성물은 표 4의 하나 이상의 종의 존재에 대해 추가로 분석될 수 있다. 일부 양태에서, 표 4의 하나 이상의 (예를 들어, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 또는 그 초과)의 종을 포함하는 것으로 확인된 조성물의 사용을 피하는 것이 바람직하다고 결정할 수 있다.

본 발명의 다른 스크리닝 방법에서, 치료 방법 (예를 들어, 본 발명의 치료 방법)에 사용하기 위한 배설물의 잠재적 공여자는 공여자로서의 역할에 적합한지 스크리닝된다. 이들 방법에서, 잠재적 공여자의 배설물 샘플은 감소된 항생제 내성 유전자와 관련된 하나 이상의 세균 종 (예를 들어, 표 3 참조; 서열은 표 5 참조) 및/또는 항생제 내성 유전자의 존재와 상관관계가 있는 하나 이상의 세균 종 (예를 들어, 표 4 참조; 서열은 표 6 참조)의 존재에 대해 스크리닝된다. 전자의 검출은 잠재적 공여자가 공여자로서의 역할을 수행하기에 적합하다는 것을 나타낼 수 있는 반면, 후자의 검출은 잠재적 공여자가 당업자에게 결정될 수 있는 바와 같이, 잠재적 공여자가 진행되지 않아야 한다는 것을 나타낼 수 있다.

추가의 스크리닝 방법은 본원에 기재된 바와 같이, 대상체가 ROAR 조성물로 치료할 수 있는지를 결정하는데 사용되는 방법을 포함한다. 이들 방법에서, 대상체로부터의 샘플 (예를 들어, 배설물 샘플)은 항생제 내성 유전자의 존재와 상관된 하나 이상의 세균 종의 존재에 대해 시험된다 (예를 들어, 표 4 및 6 참조). 이들 종 중 하나 이상의 검출은 대상이 당업자에 의해 결정될 수 있는 바와 같이, 본 발명의 치료 방법에 따른 치료로부터 이익을 얻을 수 있음을 나타낼 수 있다.

본 발명의 이들 방법에서 종의 검출은 당업계에 공지된 방법을 사용하여 수행될 수 있다 (예를 들어, 상기 및 본원의 다른 곳 참조). 예를 들어, qPCR, 전체 범유전체학 샷건 시퀀싱 (WMS; 예를 들어 이하 참조), 및/또는 16S rDNA 서열 또는 그의 일부의 분석 (예를 들어, V4 및/또는 V6 영역; 예를 들어, 표 5)을 포함하는 방법이 수행될 수 있다. 표 5로부터의 서열은 음의 상관관계의 확인 (즉, 항생제 내성 유전자의 감소)과 관련하여 검출될 수 있다. 표 6으로부터의 서열은 양의 상관관계의 확인 (즉, 증가된 항생제 내성 유전자의 존재비)과 관련하여 검출될 수 있다.

등가물

모든 기술적 특성은 이러한 특성의 가능한 모든 조합으로 개별적으로 결합될 수 있다.

본 발명은 이의 사상 또는 본질적인 특성을 벗어나지 않으면서 다른 특정 형태로 구현될 수 있다. 그러므로 전술한 양태는 모든 면에서 본 명세서에 기술된 본 발명을 제한하기보다는 예시적인 것으로 간주되어야 한다.

실시예

하기 비제한적인 예시는 본원에 기재된 본 발명의 양태를 추가로 설명한다.

실시예 1: 인간 연구 - 클로스트리듐 디피실리 ( Clostridium difficile )

재발성 클로스트리듐 디피실리 감염 (rCDI)의 위험이 있는 인간 대상체를 무작위, 이중 맹검, 위약-대조 2상 시험 (n=89; 무작위화 2:1; 36개 장소)에서 건강한 스크리닝된 인간의 대변으로부터 제조된 강화되고(enriched) 정제된 포자로 처리하였다. 포자를 단일 용량 (4 캡슐)으로 경구 투여하였다. 투약량은 10e8 포자 당량이었다. 이들 대상체의 GI 마이크로바이옴 뿐만 아니라 1b 상 개방 표지 용량 범위 연구에서 대상체는 전체 범유전체학 샷건 시퀀싱 (WMS)을 사용하여 프로파일링하였다. 대변 샘플을 포자로 처리하기 전 (항생제로 처리한 후) 및 적용 가능한 경우, 포자 또는 위약을 투여받은 후에 수집하였다.

대변 샘플에서 DNA를 추출하고 일루미나 시퀀싱 플랫폼을 WMS 데이터를 생성하는 데 사용하였다. WMS 데이터는 포괄적 항생제 내성 데이터베이스 (CARD v.1.1.8) (card.mcmaster.ca)에 기재된 바와 같이, 항생제 내성을 부여하는 것으로 알려진 단백질의 유전자 마커의 존재(presence) 및 존재비(abundance)에 대해 스크리닝하였다. 이들 단백질과 관련된 유전자 마커는 ShortBRED (Kaminski et al., PLoS Comput Biol 11 (12): e1004557), WMS 데이터 내에서 높은 특이성으로 관심있는 단백질을 확인하도록 설계된 정보 도구를 사용하여 구축하였다 (표 1). 각 종류의 항생제에 대해, 해당 종류에 대한 내성과 관련된 유전자 마커의 존재비는 정규화된 유전자 존재비 값을 생성하는 것으로 합산하였다 (본원에서 약물 종류 마커 존재비 또는 DCMA로 지칭됨).

2상 연구를 위해, WMS 분석을 기반으로 포자 형성 종의 차별 유병률을 관찰하였다. ARDB에서 확인된 항생제 내성과 관련된 유전자에 대해 ShortBRED 마커 (Kaminski et al., 상기)를 사용하여 유전자 존재비를 평가하였다 (Liu and Pop, 2009, ARDB―Antibiotic Resistance Genes Database. Nuc Acids Res 37(Database issue):D443-447). 유의한 수의 종이 투여된 ROAR 조성물에서 확인된 종과 상당히 유전적으로 유사한 것으로 확인된 대상으로 정의된, 유의한 생착 신호에 대해 데이터를 분석하였다. 데이터의 분석 결과, 조성물에 대한 중요한 생착 신호를 갖는 대상체에서, 여러 종류의 약물, 즉, 퀴놀론 약물 (도 1) 및 베타-락탐 또는 카바페넴 약물 (도 2)에 대한 내성과 관련된 유전자의 존재비가 감소함을 발견하였다.

추가 분석에서, 각 대상체 및 약물 종류 (1b 상 및 2 상 연구 모두)에 대해, 위약 또는 포자 처리 전날 수집된 샘플과 비교하여, 위약 또는 포자를 투여받은 후 방문 1주에 수집된 샘플 사이의 약물 종류 마커 존재비 (DCMA)의 로그2 배 변화 (로그2FC)를 계산하였다. 위약을 투여받은 rCDI 대상체를 포자를 받고 유의한 생착이 검출된 rCDI 대상체와 비교하였다. 위약을 받은 대상과 비교하여 DCMA의 로그2FC가 포자를 생착한 대상체에서 유의하게 더 큰지를 결정하기 위해 비모수적 맨-휘트니 검사를 사용하였다 (표 2). 여러 검사 실행으로 인한 주어진 p-값에 대해 부정확하게 기각된 귀무 가설의 예상 비율인, 거짓 발견율 (FDR)은 베냐미 호흐베르크 절차를 사용하여 계산하였다 (p <0.1)

데이터는 ROAR 조성물이 대상체에서 항생제 내성 유전자의 존재비를 감소시키기 위해 사용될 수 있음을 입증한다.

실시예 2: Abx 내성 유전자의 존재비 변화와 관련된 세균

특정 세균 종의 존재가 항생제 내성 유전자의 존재비 감소를 예측하는지를 결정하기 위한 전산 분석을 수행하였다. 이들 분석에서 확인된 종은 설계된 Abx 조성물에 사용될 수 있다. 항균 내성 유전자의 감소와 관련된 미생물 종을 확인하기 위해, 본 발명자들은 종 존재비와 위약에 비해 포자의 생착이 관찰된 대상체에서 유의한 감소를 보인 약물 종류의 DCMA 사이의 스피어맨 상관관계를 계산하였다. P-값은 상기 기재된 바와 같이 베냐미 호흐베르크 절차 (p <0.1)를 사용한 다중 가설 검정을 설명하도록 조정하였다. 항생제 내성 유전자의 적어도 하나의 약물의 현저한 감소와 관련된 종의 세트는 표 3에 요약되어 있다. 본 발명자들은 표 4에 요약된, 적어도 하나의 종류의 항생제 내성 유전자의 증가된 존재비와 양으로 상관되는 종 세트를 추가로 정의하였다. 모든 표에서 투약량 종은 대상체에게 투여된 투약량 로트에서 확인된 세균 종이다. 본원에 기재된 종의 전장 16S 서열은 표 5 (음의 상관관계) 및 6 (양의 상관관계)에 제공된다. 일부 양태에서, 세균(들)은 아래 열거된 속으로부터 유래된다. 당업자는 표준 방법을 사용하여 속을 식별할 수 있다.

표 5 - 종의 전장16S rDNA서열 (음의 상관관계)

실시예 3: 인간 연구 - 궤양성 대장염

중등도의 궤양성 대장염을 앓고 있는 인간 대상체는 위약 단독 (중재군 A), 건강한, 선별된 인간의 배설물에서 제조된 강화하고 정제된 포자의 매주 복용 (중재군 B), 짧은 코스의 반코마이신에 이어 포자의 매주 투여 (중재군 D), 또는 짧은 코스의 반코마이신에 이어 포자의 매일 투여 (중재군 C)를 받는다.

항생제가 궤양성 대장염 치료의 표준이 아니기 때문에, 이 대상체 집단은 반복 재발성 C. 디피실리 집단 (상기 실시예 1)과 비교하여 항생제로 자주 치료받을 가능성이 낮다. 따라서, 궤양성 대장염 대상체의 마이크로바이옴은 항생제 내성에 대해 강력한 선택 기간이 더 적었다. 항생제 전 기준선 샘플 (방문 1, 도 3)에서, 본 출원인은 항생제 내성 유전자의 낮은 존재비를 관찰하였다.

결과는 AbxR 유전자 존재비가 항생제 후 기준선 샘플 (방문 4, 8일)과 비교하여 처리 후 시점에서 더 낮음을 보여준다. 중재군 C 및 D에서, 반코마이신으로 처리하면 치료 후 항생제 내성 유전자가 급격히 상승한다 (방문 4, 8일). 매일 또는 매주 포자 치료는 항생제 후 기준선 (방문 4, 표 7)에 비해 방문 5 (15일, 투여 개시 후 7 일)에서 항생제 내성 유전자의 유의한 감소를 유발한다.

AbxR 유전자 존재비는 항생제 전 기준 샘플 (방문 1)과 비교하여 처리 후 시점에서 낮다. 중재군 C 및 D에서, 포자 처리는 항생제 전 기준 샘플 (방문 1, 표 8, 도 3)과 비교하여 항생제 내성 유전자 감소를 유발한다. 매일 포자 처리는 항생제 전 기준 샘플 (방문 1, 표 8)과 비교하여 방문 5 및 방문 6 (각각, 18일, 28일)에서 항생제 내성 유전자의 유의한 감소를 유발한다.

결과는 포자의 생착이 항생제 내성을 감소시킨다는 것을 보여준다. 중재군 D (매주 투약)에서, 포자는 대상체의 서브셋에서 빠르게 생착되었다 (신속 조기 생착자 = 참, 도 4). 나머지 대상체에서 생착은 규모나 시기가 감소했다 (신속 조기 생착자 = 거짓, 도 4). "신속 조기 생착자"는 방문 5 (15일)에 검출된 6 초과의 투약된 포자 형성제가 있는 대상체로 정의하였다. 본 출원인은 이러한 신속한 조기 생착 대상체가 방문 5 (15일, 포자의 제 1 투약 후 7일)에 빠른 초기 생착자로 확인되지 않은 것들과 비교하여 방문 5 (15일)에 현저하게 낮은 AbxR 유전자 존재비를 나타냄을 관찰하였다.

실시예 4: 동물 모델

항생제 내성을 감소시키는 능력에 대한 ROAR 조성물을 시험하는 한 가지 방법은 통상적인 마우스 (마이크로바이옴을 갖는 실험실 균주)를 사용한다. 선택된 항생제로 마우스를 처리한 후, 하나 이상의 항생제 내성 유전자, 예를 들어 반코마이신 내성 장구균 (vancomycin resistant Enterococcus; VRE) 또는 반코마이신 및 카바페넴 내성 장내 세균 (carbapenem resistant Enterobacteriaceae; CRE)를 보유하는 세균으로 콜로니화한다. 콜로니화 후, 마우스를 ROAR 조성물, 분변 이식 또는 대조군으로 처리하였다. 항생제 내성 세균의 역가 (예를 들어, 반코마이신 내성 및 카바페넴 내성 세균)를 처리된 동물로부터 수집된 대변의 플레이팅을 통해 모니터링한다.

출원인은 공개된 모델 (Caballero and Pamer, 2015, Ann Rev Immunol 33:227-256)을 기초로 하여 마우스에서 재현성있고 탄탄한 반코마이신-내성 장구균 (VRE) 콜로니화 모델을 확립하였다. VRE 접종 전에, 특정 병원체 유리 (SPF) 마우스는 콜로니 내성을 파괴하고 VRE 콜로니화를 허용하기 위해 암피실린으로 사전 조절된다. 암피실린 처리 후, 마우스를 VRE로 챌린지시키고 GI 관에서 높은 역가 (10⁷ 내지 10¹⁰ CFU/g 배설물) 캐리지를 달성하고, 이는 수 주 동안 안정한 상태이다. VRE로 콜로니화되면, 마우스를 3일 동안 매일 경구 위관 영양법을 통해 인간 FMT 또는 ROAR 내성 조성물로 처리한다. 마우스로부터 VRE를 제거하고 건강한 장내 미생물을 회복시키는 조성물의 능력을 평가하기 위해 연구 전반에 걸쳐 신선한 배설물 샘플을 수집하였다. 처리 전 및 처리 후 배설물에서의 VRE 생존 역가는 반코마이신 및 스트렙토마이신을 갖는 담즙 에스쿨린 아지드 한천을 함유하는 선택적 배지 상에 플레이팅함으로써 측정한다. VRE 콜로니 모델은 PBS로만 처리된 마우스와 비교하여 인간 FMT로 처리된 마우스에서 3주에 걸친 콜로니화의 >4 로그 차이를 검출할 수 있다. 연구 기간 동안 VRE 역가에서 >4 로그 차이를 검출하는 능력은 또한 차등 효능을 갖는 설계된 미생물 조성물을 구별하였다. 또한, 항생제 내성 유전자의 존재비를 분석할 수 있다. CRE에 적합한 선택적 배지를 대체하여, 카바페넴 내성 장내 세균 (CRE) 내성을 비슷한 방식으로 시험할 수 있다.

이러한 모델을 사용하여, 항생제 내성 유전자의 존재비에 대한 ROAR 조성물의 효과를 시험할 수 있다. 이러한 모델에서 하나 이상의 항생제 내성 유전자의 존재비를 감소시킬 수 있는 ROAR 조성물은 본원에 기재된 방법에 대해 유용하다.

본 발명의 다양한 양태는 하기 번호가 매겨진 절 내에 존재한다.

1. 대상체의 마이크로바이옴에서, 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는 방법으로서, 치료적 유효량의 포자-형성자 세균을 포함하는 마이크로바이옴 조성물을 투여하는 것을 포함하는 방법.

2. 바람직하지 못한 수준 또는 집단의 약물 내성 세균을 가질 위험이 있거나 가진 것으로 진단된 대상체를 치료하는 방법으로서, 방법은 하나 이상의 건강한 인간 대상체로부터 유래된 후벽균을 포함하는 치료적 유효량의 마이크로바이옴 조성물을 투여하는 것을 포함하는 방법.

3. 대상체의 마이크로바이옴에서 항생제 내성 세균의 존재비를 감소시키는 방법으로서, 치료적 유효량의 ROAR 조성물을 투여하는 것을 포함하는 방법.

4. 항생제 내성 유전자의 전달 주기를 방해하는 방법으로서, 체액 또는 노폐물과의 접촉을 포함하여 직접 또는 간접적으로 접촉할 가능성이 큰 적어도 2 명의 개체에게 ROAR 조성물을 투여하는 것을 포함하는 방법.

5. 절 1에 있어서, 항생제 내성 유전자(들)이 표 1에 열거된 것들로부터 선택되는 방법.

6. 절 5에 있어서, 표 1의 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 초과의 항생제 내성 유전자의 존재비가 감소되는 방법.

7. 절 1 내지 6 중 어느 한 절에 있어서, 약물 또는 항생제가 표 2에 열거된 약물 종류로부터 유래된 방법.

8. 절 1 내지 절 7 중 어느 한 절에 있어서, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25개 또는 그 초과의 항생제 내성 유전자 또는 약물 종류의 존재비를 감소시키는 단계를 추가로 포함하는 방법.

9. 절 1 내지 8 중 어느 한 절에 있어서, 투여된 조성물은 표 3에 열거된 하나 이상의 종을 포함하는 방법.

10. 절 9에 있어서, 투여된 조성물이 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함하는 방법.

11. 절 9 또는 10에 있어서, 투여된 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는 방법.

12. 절 1 내지 11 중 어느 한 절에 있어서, 투여된 조성물은 표 4의 하나 이상의 종을 포함하지 않는 방법.

13. 절 1 내지 12 중 어느 한 절에 있어서, 조성물 중 세균이 포자의 형태인 방법.

14. 절 1 내지 13 중 어느 한 절에 있어서, 조성물 중의 세균이 배양되는 방법.

15. 절 1 내지 14 중 어느 한 절에 있어서, 상기 조성물은 후벽군 및 하나 이상의 박테로이데스 종을 포함하는 방법.

16. 절 1 내지 15 중 어느 한 절에 있어서, 대상체는 퀴놀론 내성, 베타-락탐 내성 및 카바페넴 내성 세균으로 이루어진 군으로부터 선택된 1, 2 또는 3개의 세균의 감소된 존재비를 가지는 방법

17. 절 1 내지 16 중 어느 한 절에 있어서, 대상체가 항생제 치료에 반응하지 않는 방법.

18. 절 1 내지 17 중 어느 한 절에 있어서, 대상체가 C. 디피실리 감염이 있거나 발병할 위험이 있는 방법.

19. 절 1 내지 18 중 어느 한 절에 있어서, 대상체가 대장염을 앓거나 발병할 위험이 있는 방법.

20. 절 19에 있어서, 대장염이 크론병 또는 궤양성 대장염인 방법.

21. 절 20에 있어서, 대장염이 경증 내지 중등도의 궤양성 대장염인 방법.

22. 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비 감소와 관련된 세균 종을 포함하는 조성물.

23. 절 22에 있어서, 항생제-내성 유전자(들)가 표 1에 열거된 것들로부터 선택되는 조성물.

24. 절 23에 있어서, 표 1의 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 초과의 항생제 내성 유전자의 존재비가 감소되는 조성물.

25. 절 22 내지 24 중 어느 한 절에 있어서, 항생제는 표 2에 열거된 종류인 조성물.

26. 절 22 내지 25 중 어느 한 절에 있어서, 조성물은 표 3에 열거된 하나 이상의 종을 포함하는 조성물.

27. 절 26에 있어서, 조성물은 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함하는 조성물.

28. 절 20 또는 27에 있어서, 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는 조성물.

29. 절 22 내지 28 중 어느 한 절에 있어서, 조성물은 표 4의 하나 이상의 종을 포함하지 않고, 선택적으로 표 4의 하나 이상의 종은 표 6에서 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는 조성물.

30. 절 22 내지 29 중 어느 한 절에 있어서, 조성물은 하나 이상의 종의 후벽군을 포함하는 조성물.

31. 절 22 내지 30 중 어느 한 절에 있어서, 조성물은 하나 이상의 종의 박테로이데스를 포함하는 조성물.

32. 절 22 내지 31 중 어느 한 절에 있어서, 조성물 중의 세균은 포자의 형태인 조성물.

33. 절 22 내지 32 중 어느 한 절에 있어서, 조성물 중 세균은 건강한 대상의 배설물로부터 유래된 포자 분획으로부터 수득되는 조성물.

34. 절 22 내지 33 중 어느 한 절에 있어서, 조성물은 하나 이상의 후벽군 종, 및 선택적으로 하나 이상의 박테로이데스 종을 조성물 중의 유일한 세균 종으로 포함하는 조성물.

35. 절 22 내지 34 중 어느 한 절에 있어서, 조성물 중의 세균이 배양되는 조성물.

36. 조성물이 투여되는 대상체에서 하나 이상의 항생제 내성 유전자의 존재비를 감소시키는 데 사용하기 위한 세균을 포함하는 조성물.

37. 절 36에 있어서, 조성물 중 세균이 건강한 대상의 배설물로부터 유래된 포자 분획으로부터 수득되는 조성물.

38. 절 36에 있어서, 세균이 대상체에서 하나 이상의 항생제 내성 유전자의 존재 감소와 관련되도록 선택되는 절 36의 조성물.

39. 절 36 내지 38 중 어느 한 절에 있어서, 항생제 내성 유전자(들)은 표 1로부터 선택되는 조성물.

40. 절 36 내지 39 중 어느 한 절에 있어서, 조성물은 표 3에서 선택된 적어도 하나의 종을 포함하는 조성물.

41. 절 36 내지 40 중 어느 한 절에 있어서, 조성물은 표 4의 종을 포함하지 않는 조성물.

42. 조성물이 투여되는 대상체에서 하나 이상의 항생제 내성 유전자의 존재비를 감소시키는 데 유용한 세균 조성물을 확인하는 방법에 있어서, 표 3의 하나 이상의 세균 종의 존재에 대해 조성물을 스크리닝하는 단계를 포함하고, 세균 조성물에서 표 3의 하나 이상의 종의 검출은 하나 이상의 항생제 내성 유전자의 존재비를 감소시키기 위해 사용될 수 있는 조성물의 확인을 나타내는 방법.

43. 절 42에 있어서, 스크리닝은 조성물에서 표 5의 하나 이상의 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열의 검출을 포함하는 방법.

44. 절 42 또는 43에 있어서, 표 4의 하나 이상의 세균 종의 존재에 대한 스크리닝을 추가로 포함하고, 선택적으로 표 4의 하나 이상의 종은 표 6에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는 방법.

45. 치료적 방법에 사용하기 위한 잠재적 공여자를 스크리닝하는 방법으로서, 표 3 또는 표 4의 세균 종의 존재에 대해 잠재적 공여자로부터의 배설물 샘플을 시험하는 단계를 포함하고, 표 3으로부터의 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 될 수 있음을 나타내고, 표 4로부터 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 되지 않아야 함을 나타내는 방법.

46. 대상체가 ROAR 조성물로 치료함으로써 이익을 얻을 수 있는지를 결정하는 방법으로서, 대상체로부터의 샘플이 표 4의 하나 이상의 세균 종을 포함하는지를 결정하는 단계를 포함하고, 표 4로부터 하나 이상의 종의 검출은 대상체가 ROAR 조성물로 치료함으로써 이익을 얻을 수 있다는 점을 나타내는 방법.

47. 절 22 내지 41 중 어느 한 절에 있어서, 조성물 중의 세균은 항생제 내성의 동물 모델에서 하나 이상의 항생제 내성 유전자(들)의 존재비를 감소시키는 능력을 나타내는 조성물.

48. 절 47에 있어서, 동물 모델이 하나 이상의 항생제로 처리된 후 하나 이상의 항생제 내성 유전자를 보유하는 하나 이상의 세균으로 콜로니화된 마우스를 포함하는 조성물.

49. 절 48에 있어서, 마우스는 반코마이신 내성 세균 또는 반코마이신 및 카바페넴 내성 세균으로 콜로니화되는 조성물.

다른 양태는 하기 청구항의 범위 내에 존재한다.

<110> Seres Therapeutics, Inc. <120> COMPOSITIONS AND METHODS FOR TREATING ANTIBIOTIC RESISTANCE <130> 51069-022WO3 <150> US 62/741,346 <151> 2018-10-04 <150> US 62/578,698 <151> 2017-10-30 <160> 405 <170> PatentIn version 3.5 <210> 1 <211> 869 <212> DNA <213> Clostridium difficile <400> 1 ttatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 cgaacgcttc tttttccacc ggagcttgct ccaccggaaa aagaggagtg gcgaacgggt 120 gagtaacacg tgggtaacct gcccatcaga aggggataac acttggaaac aggtgctaat 180 accgtataac aatcgaaacc gcatggtttt gatttgaaag gcgctttcgg gtgtcgctga 240 tggatggacc cgcggtgcat tagctagttg gtgaggtaac ggctcaccaa ggccacgatg 300 catagccgac ctgagagggt gatcggccac attgggactg agacacggcc caaactccta 360 cgggaggcag cagtagggaa tcttcggcaa tggacgaaag tctgaccgag caacgccgcg 420 tgagtgaaga aggttttcgg atcgtaaaac tctgttgtta gagaagaaca aggatgagag 480 taactgttca tcccttgacg gtatctaacc agaaagccac ggctaactac gtgccagcag 540 ccgcggtaat acgtaggtgg caagcgttgt ccggatttat tgggcgtaaa gcgagcgcag 600 gcggtttctt aagtctgatg tgaaagcccc cggctcaacc ggggagggtc attggaaact 660 gggagacttg agtgcagaag aggagagtgg aattccatgt gtagcggtga aatgcgtaga 720 tatatggagg aacaccagtg gcgaaggcgg ctctctggtc tgtaactgac gctgaggctc 780 gaaagcgtgg ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgagt 840 gctaagtgtt ggagggtttc cgcccttca 869 <210> 2 <211> 869 <212> DNA <213> Clostridium difficile <400> 2 ttatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 cgaacgcttc tttttccacc ggagcttgct ccaccggaaa aagaggagtg gcgaacgggt 120 gagtaacacg tgggtaacct gcccatcaga aggggataac acttggaaac aggtgctaat 180 accgtataac aatcgaaacc gcatggtttt gatttgaaag gcgctttcgg gtgtcgctga 240 tggatggacc cgcggtgcat tagctagttg gtgaggtaac ggctcaccaa ggccacgatg 300 catagccgac ctgagagggt gatcggccac attgggactg agacacggcc caaactccta 360 cgggaggcag cagtagggaa tcttcggcaa tggacgaaag tctgaccgag caacgccgcg 420 tgagtgaaga aggttttcgg atcgtaaaac tctgttgtta gagaagaaca aggatgagag 480 taactgttca tcccttgacg gtatctaacc agaaagccac ggctaactac gtgccagcag 540 ccgcggtaat acgtaggtgg caagcgttgt ccggatttat tgggcgtaaa gcgagcgcag 600 gcggtttctt aagtctgatg tgaaagcccc cggctcaacc ggggagggtc attggaaact 660 gggagacttg agtgcagaag aggagagtgg aattccatgt gtagcggtga aatgcgtaga 720 tatatggagg aacaccagtg gcgaaggcgg ctctctggtc tgtaactgac gctgaggctc 780 gaaagcgtgg ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgagt 840 gctaagtgtt ggagggtttc cgcccttca 869 <210> 3 <211> 869 <212> DNA <213> Clostridium difficile <400> 3 ttatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 cgaacgcttc tttttccacc ggagcttgct ccaccggaaa aagaggagtg gcgaacgggt 120 gagtaacacg tgggtaacct gcccatcaga aggggataac acttggaaac aggtgctaat 180 accgtataac aatcgaaacc gcatggtttt gatttgaaag gcgctttcgg gtgtcgctga 240 tggatggacc cgcggtgcat tagctagttg gtgaggtaac ggctcaccaa ggccacgatg 300 catagccgac ctgagagggt gatcggccac attgggactg agacacggcc caaactccta 360 cgggaggcag cagtagggaa tcttcggcaa tggacgaaag tctgaccgag caacgccgcg 420 tgagtgaaga aggttttcgg atcgtaaaac tctgttgtta gagaagaaca aggatgagag 480 taactgttca tcccttgacg gtatctaacc agaaagccac ggctaactac gtgccagcag 540 ccgcggtaat acgtaggtgg caagcgttgt ccggatttat tgggcgtaaa gcgagcgcag 600 gcggtttctt aagtctgatg tgaaagcccc cggctcaacc ggggagggtc attggaaact 660 gggagacttg agtgcagaag aggagagtgg aattccatgt gtagcggtga aatgcgtaga 720 tatatggagg aacaccagtg gcgaaggcgg ctctctggtc tgtaactgac gctgaggctc 780 gaaagcgtgg ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgagt 840 gctaagtgtt ggagggtttc cgcccttca 869 <210> 4 <211> 1530 <212> DNA <213> Fusicatenibacter_saccharivorans <400> 4 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca gttaagttga tttcttcgga ttgattcttg actgactgag cggcggacgg 120 gtgagtaacg cgtgggtgac ctgccccata ccgggggata acagctggaa acggctgcta 180 ataccgcata agcgcacaga gctgcatggc tcggtgtgaa aaactccggt ggtatgggat 240 gggcccgcgt ctgattaggc agttggcggg gtaacggccc accaaaccga cgatcagtag 300 ccggcctgag agggcgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gataatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcaaggc aagtctgatg tgaaaaccca 600 gggcttaacc ctgggactgc attggaaact gtctggctcg agtgccggag aggtaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggaag aacaccagtg gcgaaggcgg 720 cttactggac ggtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat gctaggtgtt ggggagcaaa gctcttcggt 840 gccgccgcaa acgcattaag cattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caggtcttga catcccgatg accggcccgt aacggggctt tctcttcgga 1020 gcattggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatcctcag tagccagcag gtaaagctgg gcactctgtg 1140 gagactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgatctgggc tacacacgtg ctacaatggc gtaaacaaag ggaggcaaag ccgcgaggtg 1260 gagcaaatcc caaaaataac gtctcagttc ggactgcagt ctgcaactcg actgcacgaa 1320 gctggaatcg ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg taacgcccga agtcagtgac ccaacctttt 1440 aggagggagc tgccgaaggc gggactgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 5 <211> 1530 <212> DNA <213> Lachnospira pectinoschiza <400> 5 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttaagaca gattacttcg gtttgaagtc ttttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctc atacaggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac agtaccacat ggtacagtgt gaaaaactcc ggtggtatga 240 gatggacccg cgtctgatta gcttgttggc ggggtaacgg cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag tagttcgcta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca ggcaagtcag aagtgaaagc 600 ccggggctca accccgggac tgcttttgaa actgcagggc tagagtgcag gaggggcaag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggcttgctg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggcac ataagtgctc 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatcct cttgaccggt cagtaatgtg accttttctt 1020 cggaacaaga gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccttatcc ttagtagcca gcagttcggc tgggcactct 1140 agggagactg ccagggataa cctggaggaa ggtggggatg acgtcaaatc atcatgcccc 1200 ttatgacttg ggctacacac gtgctacaat ggcgtaaaca aagtgaagcg agagcgtgag 1260 cttaagcaaa tcacaaaaat aacgtctcag ttcggattgt agtctgcaac tcgactacat 1320 gaagctggaa tcgctagtaa tcgcagatca gaatgctgcg gtgaatacgt tcccgggtct 1380 tgtacacacc gcccgtcaca ccatgggagt cggaaatgcc cgaagtcggt gacctaacgt 1440 aagaaggagc cgccgaaggc aggtctgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 6 <211> 1305 <212> DNA <213> Clostridium_sp. <400> 6 tccggtggta tgagatggac ccgcgtctga ttagctagtt ggtgaggtaa cggcccacca 60 aggcgacgat cagtagccga cctgagaggg tgaccggcca cattgggact gagacacggc 120 ccagactcct acgggaggca gcagtggggg atattgcaca atggaggaaa ctctgatgca 180 gcgacgccgc gtgagtgaag aagtatttcg gtatgtaaag ctctatcagc agggaagaaa 240 atgacggtac ctgactaaga agccccggct aactacgtgc cagcagccgc ggtaatacgt 300 agggggcaag cgttatccgg atttactggg tgtaaaggga gcgtagacgg cgacgcaagt 360 ctgaagtgaa atacccgggc tcaacctggg aactgctttg gaaactgtgt tgctagagtg 420 ctggagaggt aagcggaatt cctagtgtag cggtgaaatg cgtagatatt aggaagaaca 480 ccagtggcga aggcggctta ctggacagta actgacgttg aggctcgaaa gcgtggggag 540 caaacaggat tagataccct ggtagtccac gccgtaaacg atgaatacta ggtgttggtg 600 agcaaagctc atcggtgccg ccgcaaacgc aataagtatt ccacctgggg agtacgttcg 660 caagaatgaa actcaaagga attgacgggg acccgcacaa gcggtggagc atgtggttta 720 attcgaagca acgcgaagaa ccttaccaaa tcttgacatc cctctgaaaa gcctttaatc 780 gggctcctcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 840 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgtcagtagc cagcaggtaa 900 agctgggcac tctgatgaga ctgccaggga taacctggag gaaggtgggg atgacgtcaa 960 atcatcatgc cccttatgat ttgggctaca cacgtgctac aatggcgtaa acaaagagaa 1020 gcgagcctgc gagggggagc aaatctcaaa aataacgtct cagttcggat tgtagtctgc 1080 aactcgacta catgaagctg gaatcgctag taatcgcaga tcagaatgct gcggtgaata 1140 cgttcccggg tcttgtacac accgcccgtc acaccatggg agtcggaaat gcccgaagcc 1200 agtgacccaa gcgaaagcag ggagctgtcg aaggcaggtc tgataactgg ggtgaagtcg 1260 taacaaggta gccgtatcgg aaggtgcggc tggatcacct ccttt 1305 <210> 7 <211> 1528 <212> DNA <213> Ruminococcus_sp. <400> 7 tacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagca cttaagtttg attcttcgga tgaagacttt tgtgactgag tggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atggctgcta 180 ataccgcata agaccacagc accgcatggt gcaggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct ggttggtggg gtaacggcct accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgaag 420 gatgaagtat ttcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggtatggc aagtctgatg tgaaaggcca 600 gggctcaacc ctgggactgc attggaaact gtcgaactag agtgtcggag aggcaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttgctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtagcaga gctattcggt 840 gccgcagcca acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catctccctg accggcaagt aatgttgcct ttccttcggg 1020 acagggatga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg tacggccggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc tgcgagggta 1260 agcaaatctc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 8 <211> 1530 <212> DNA <213> Clostridium_sp. <400> 8 tttagagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgagcgaagc acttatggag attcttcgga tgatccattt gtgactgagc ggcggacggg 120 tgagtaacgc gtgagtaacc tgcctcatac aggggaataa cagttagaaa tgactgctaa 180 tgccgcataa gcgcacaggg ccacatggcc tggtgtgaaa aactccggtg gtatgagatg 240 gactcgcgtc tgattagcta gttggtgagg taacggccca ccaaggcgac gatcagtagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagtg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctttgca agtctgacgt gaaaatccgg 600 ggctcaaccc cggaactgcg ttggaaactg tgaggcttga gtgccggaga ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gcaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgcggtaa acgatgaata ctaggtgttg ggggacaaag tccttcggtg 840 ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atcgattcgc cgggactgta atgagtcctt tcccttcggg 1020 gacgaagaag acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttca gtagccagca agtgaagttg ggcactctgg 1140 agagactgcc agggacaacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgacttggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcagc cctgtgaagg 1260 tgagcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtcg gtaacgcccg aagtcagtga cccaaccgaa 1440 aggagggagc tgccgaaggc gggactggta actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 9 <211> 1306 <212> DNA <213> Blautia_faecis <400> 9 ctccggtggt ataagatgga cccgcgttgg attagctagt tggcagggca gcggcctacc 60 aaggcgacga tccatagccg gcctgagagg gtgaacggcc acattgggac tgagacacgg 120 cccagactcc tacgggaggc agcagtgggg aatattgcac aatgggggaa accctgatgc 180 agcgacgccg cgtgaaggaa gaagtatctc ggtatgtaaa cttctatcag cagggaagat 240 aatgacggta cctgactaag aagccccggc taactacgtg ccagcagccg cggtaatacg 300 tagggggcga gcgttatccg gatttactgg gtgtaaaggg agcgtagacg gcgtatcaag 360 tctgatgtga aaggcagggg cttaacccct ggactgcatt ggaaactggt atgcttgagt 420 gccggagggg taagcggaat tcctagtgta gcggtgaaat gcgtagatat taggaggaac 480 accagtggcg aaggcggctt actggacggt aactgacgtt gaggctcgaa agcgtgggga 540 gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgaatact aggtgtctgg 600 gagcacagct cttaggtgcc gccgcaaacg cattaagtat tccacctggg gagtacgttc 660 gcaagaatga aactcaaagg aattgacggg gacccgcaca agcggtggag catgtggttt 720 aattcgaagc aacgcgaaga accttaccaa atcttgacat ccctctgaca gagtatgtaa 780 tgtacttttc cttcgggaca ggggagacag gtggtgcatg gttgtcgtca gctcgtgtcg 840 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta tccttagtag ccagcaagta 900 atgttgggca ctctgaggag actgccaggg ataacctgga ggaaggcggg gatgacgtca 960 aatcatcatg ccccttatga tttgggctac acacgtgcta caatggcgta aacaaaggga 1020 agcgaacctg tgagggtggg caaatctcaa aaataacgtc ccagttcgga ctgcagtctg 1080 caactcgact gcacgaagct ggaatcgcta gtaatcgcgg atcagaatgc cgcggtgaat 1140 acgttcccgg gtcttgtaca caccgcccgt cacaccatgg gagtcagtaa cgcccgaagt 1200 cagtgaccta accgtaagga aggagctgcc gaaggcggga cggatgactg gggtgaagtc 1260 gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tccttt 1306 <210> 10 <211> 1522 <212> DNA <213> Clostridium_sp. <400> 10 taaagagttt gatcctggct caggacgaac gctgtcggcg cgcctaacac atgcaagtcg 60 aacgaagttg ctttgaatga attcttcgga aggaatttga ttcaacttag tggcggacgg 120 gtgagtaacg cgtgagtaac ctgcctttca gagggggata acgtctggaa acggacgcta 180 ataccgcata acatattggt ttcgcatgga gctgatatca aaggagcaat ccgctgaaag 240 atggactcgc gtccaattag ctagttggtg aggtaacggc ccaccaaggc gacgattggt 300 agccggactg agaggttgaa cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgagtga 420 gggaagaagg ttttcggatt gtaaacctct gtccttggtg aagataatga cggtaaccaa 480 ggaggaagct acggctaact acgtgccagc agccgcggta atacgtaggt agcgagcgtt 540 gtccggaatt actgggtgta aagggagcgt aggcgggatt gcaagttgaa tgttaaatct 600 atgggctcaa cccatagccg cgttcaaaac tgcagttctt gagtgaagta gaggcaggcg 660 gaattcctag tgtagcggtg aaatgcgtaa atattaggag gaacaccagt ggcgaaggcg 720 gcctgctggg ctttaactga cgctgaggct cgaaagcgtg ggtagcaaac aggattagat 780 accctggtag tccacgctgt aaacgatgat tactaggtgt ggggggactg accccttccg 840 tgccggagtt aacacaataa gtaatccacc tggggagtac gaccgcaagg ttgaaactca 900 aaggaattga cgggggcccg cacaagcagt ggagtatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaggtcttg acatccggtg catagcctag agataggtga agcccttcgg 1020 ggcaccgaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttacgtttag ttgctacgca agagcactct agacggactg 1140 ccgttgacaa aacggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg 1200 ggctacacac gtactacaat ggctattaac agagggaagc aagatggtga catggagcaa 1260 acccctaaaa atagtctcag ttcggattgc aggctgcaac ccgcctgcat gaagccggaa 1320 ttgctagtaa tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc 1380 gcccgtcaca ccatgagagt tggcaacacc cgaagccgat agtctaaccg caagggggac 1440 gtcgtcgaag gtggggttga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag 1500 gtgcggctgg atcacctcct tt 1522 <210> 11 <211> 1515 <212> DNA <213> Clostridium_sp. <400> 11 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacggaattt acatgaagcc tagcgattgt aaatttagtg gcggacgggt gagtaacgcg 120 tgggtaacct gccttgtact gggggacaac agttggaaac gactgctaat accgcataag 180 cgcacagctt cgcatgaagc agtgtgaaaa actccggtgg tacaagatgg acccgcgtct 240 gattagctgg ttggtgaggt aacggcccac caaggcgacg atcagtagcc ggcctgagag 300 ggtgaacggc cacattggga ctgagacacg gcccaaactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcaacgcc gcgtgagtga agaagtattt 420 cggtatgtaa agctctatca gcaggaaaga aaatgacggt acctgactaa gaagccccgg 480 ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc ggatttactg 540 ggtgtaaagg gagcgtagac ggttttgcaa gtctgaagtg aaagcccggg gcttaacccc 600 gggactgctt tggaaactgt aggactagag tgcaggagag gtaagtggaa ttcctagtgt 660 agcggtgaaa tgcgtagata ttaggaggaa caccagtggc gaaggcggct tactggactg 720 taactgacgt tgaggctcga aagcgtgggg agcaaacagg attagatacc ctggtagtcc 780 acgccgtaaa cgatgattac taggtgttgg tgggtacgac ccatcggtgc cgcagcaaac 840 gcaataagta atccacctgg ggagtacgtt cgcaagaatg aaactcaaag gaattgacgg 900 ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag aaccttacct 960 ggtcttgaca tccctatgaa taacgggcaa tgccgttagt acttcggtac ataggagaca 1020 ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag 1080 cgcaaccctt atctttagta gccagcagta agatgggcac tctagagaga ctgccgggga 1140 taacccggag gaaggtgggg atgacgtcaa atcatcatgc cccttatgac cagggctaca 1200 cacgtgctac aatggcgtaa acaaagagaa gcgaagtcgt gaggcagagc gaatctcaaa 1260 aataacgtct cagttcggat tgtagtctgc aactcgacta catgaagctg gaatcgctag 1320 taatcgcaga tcagaatgct gcggtgaata cgttcccggg tcttgtacac accgcccgtc 1380 acaccatggg agtcggaaat gcccgaagtc ggtgacctaa ccgaaaggaa ggagccgccg 1440 aaggcaggtc tgataactgg ggtgaagtcg taacaaggta gccgtatcgg aaggtgcggc 1500 tggatcacct ccttt 1515 <210> 12 <211> 1558 <212> DNA <213> Clostridium_sp. <220> <221> misc_feature <222> (992)..(1038) <223> n is a, c, g, or t <400> 12 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaggtat tttgattgaa gttttcggat ggatttcaag ataccgagtg gcggacgggt 120 gagtaacgcg tgggtaacct gcctcataca gggggataac ggttagaaat gactgctaat 180 accgcataag cgcacagtac cgcatggtac ggtgtgaaaa actccggtgg tatgagatgg 240 acccgcgtct gattagctag ttggtggggt aacggcccac caaggcgacg atcagtagcc 300 gacctgagag ggtgaccggc cacattggga ctgagacacg gcccagactc ctacgggagg 360 cagcagtggg ggatattgca caatggagga aactctgatg cagcgacgcc gcgtgagtga 420 agaagtattt cggtatgtaa agctctatca gcagggaaga aaatgacggt acctgactaa 480 gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc 540 ggatttactg ggtgtaaagg gagcgtagac ggcgacgcaa gtctgaagtg aaatacccgg 600 gctcaacctg ggaactgctt tggaaactgt gttgctagag tgctggagag gtaagcggaa 660 ttcctagtgt agcggtgaaa tgcgtagata ttaggaagaa caccagtggc gaaggcggct 720 tactggacag taactgacgt tgaggctcga aagcgtgggg agcaaacagg attagatacc 780 ctggtagtcc acgccgtaaa cgatgaatac taggtgttgg tgagcaaagc tcatcggtgc 840 cgccgcaaac gcaataagta ttccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca aatcttgaca tccctctgaa annnnnnnnn nnnnnnnnnn nnnnnnnnnn 1020 nnnnnnnnnn nnnnnnnncc tccttcggga cagaggtgac aggtggtgca tggttgtcgt 1080 cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc tattgtcagt 1140 agccagcagg taaagctggg cactctgatg agactgccag ggataacctg gaggaaggtg 1200 gggatgacgt caaatcatca tgccccttat gatttgggct acacacgtgc tacaatggcg 1260 taaacaaaga gaagcgagcc tgcgaggggg agcaaatctc aaaaataacg tctcagttcg 1320 gattgtagtc tgcaactcga ctacatgaag ctggaatcgc tagtaatcgc agatcagaat 1380 gctgcggtga atacgttccc gggtcttgta cacaccgccc gtcacaccat gggagtcgga 1440 aatgcccgaa gccagtgacc caagcgaaag cagggagctg tcgaaggcag gtctgataac 1500 tggggtgaag tcgtaacaag gtagccgtat cggaaggtgc ggctggatca cctccttt 1558 <210> 13 <211> 1529 <212> DNA <213> Flavonifractor_sp. <400> 13 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggagt gctcatgaca gaggattcgt ccaatggagt gagttactta gtggcggacg 120 ggtgagtaac gcgtgagtaa cctgccttgg agtggggaat aacaggtgga aacatctgct 180 aataccgcat gatgcagttg ggtcgcatgg ctctgactgc caaagattta tcgctctgag 240 atggactcgc gtctgattag ctggttggcg gggtaacggc ccaccaaggc gacgatcagt 300 agccggactg agaggttggc cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg gcgcaagcct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttctcaggg acgaagcaag tgacggtacc 480 tgaggaataa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcgagc 540 gttatccgga tttactgggt gtaaagggcg tgtaggcggg actgcaagtc agatgtgaaa 600 accatgggct caacctgtgg cctgcatttg aaactgtagt tcttgagtac tggagaggca 660 gacggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagtggcgaa 720 ggcggtctgc tggacagcaa ctgacgctga ggcgcgaaag cgtggggagc aaacaggatt 780 agataccctg gtagtccacg ctgtaaacga tggatactag gtgtgggggg tctgaccccc 840 tccgtgccgc agttaacaca ataagtatcc cacctgggga gtacgatcgc aaggttgaaa 900 ctcaaaggaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa ttcgaagcaa 960 cgcgaagaac cttaccaggg cttgacatcc cggtgaccgg tgtagagata caccttcttc 1020 ttcggaagcg ccggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg 1080 ggttaagtcc cgcaacgagc gcaaccctta ttgttagttg ctacgcaaga gcactctagc 1140 gagactgccg ttgacaaaac ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgtcctgggc cacacacgta ctacaatggt ggtcaacaga gggaagcaag accgcgaggt 1260 ggagcaaacc cctaaaagcc atcccagttc ggattgcagg ctgcaactcg cctgtatgaa 1320 gttggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttcc cgggccttgt 1380 acacaccgcc cgtcacacca tgagagtcgg gaacacccga agtccgtagc ctaaccgcaa 1440 ggggggcgcg gccgaaggtg ggttcgataa ttggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 14 <211> 1514 <212> DNA <213> Emergencia_timonensis <400> 14 attaagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgagaag ccattgaccg atacttcggt aaagggatat ggcggaaagc ggcggacggg 120 tgagtaacgc gtaggcaacc tgccccttac agagggatag ccattggaaa cgatgattaa 180 gacctcataa cgcctccctc ccacatgagg gggaggccaa agattcatcg gtaagggatg 240 ggcctgcgtc tgattagctt gttggcgggg taacggccca ccaaggcgac gatcagtagc 300 cgacctgaga gggtgatcgg ccacattgga actgagacac ggtccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg gaagcctgat gcagcaacgc cgcgtgaggg 420 atgaaggcct tcgggtcgta aacctctgtc cttggggaag aaacaaatga cggtacccat 480 ggaggaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcgagcgtt 540 atccggaatt attgggcgta aagagtgcgt aggtggttac ctaagcgcag ggtctaaggc 600 aatggctcaa ccattgttcg ccctgcgaac tgggctactt gagtgcagga gaggaaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gctttctgga ctgttactga cactgaggca cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgag cactaggtgt cggggccgca aggcttcggt 840 gccgcagtta acgcattaag tgctccgcct ggggagtacg cacgcaagtg tgaaactcaa 900 aggaattgac ggggacccgc acaagcagcg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caggacttga catccccctg acagatcctt aaccggatcc ttcttcggac 1020 aggggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt gccattagtt gccatcattc agttgggcac tctaatggga 1140 ctgccgggga caactcggag gaaggtgggg atgacgtcaa atcatcatgc cccttatgtt 1200 ctgggctaca cacgtgctac aatggccggt acagcaggaa gcgatcccgc gagggggagc 1260 aaatcccaaa aaccggtccc agttcggact gcaggctgca acccgcctgc acgaagccgg 1320 agttgctagt aatcgtggat cagaatgcca cggtgaatgc gttcccgggt cttgtacaca 1380 ccgcccgtca caccatggaa gttgggggtg cccgaagccg gcagggagat atgctgtcta 1440 aggcaaaacc aatgactggg gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct 1500 ggatcacctc cttt 1514 <210> 15 <211> 1527 <212> DNA <213> Clostridium_sp. <400> 15 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaggtaa atgagatgaa gttttcggat ggattcttat ttaccgagtg gcggacgggt 120 gagtaacgcg tgggtaacct gcctcataca gggggataac gattggaaac gattgctaat 180 accgcataag cgcacagtac cacatggtac agtgtgaaaa actccggtgg tatgagatgg 240 acccgcgtct gattagctag ttggtgaggt aacggcccac caaggcaacg atcagtagcc 300 gacctgagag ggtgaccggc cacattggga ctgagacacg gcccagactc ctacgggagg 360 cagcagtggg ggatattgca caatggagga aactctgatg cagcgacgcc gcgtgagtga 420 agaagtattt cggtatgtaa agctctatca gcagggaaga aaatgacggt acctgactaa 480 gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc 540 ggatttactg ggtgtaaagg gagcgtagac ggcgatgcaa gtctgaagtg aaatacccgg 600 gctcaacctg ggaactgctt tggaaactgt atggctagag tgctggagag gtaagcggaa 660 ttcctagtgt agcggtgaaa tgcgtagata ttaggaagaa caccagtggc gaaggcggct 720 tactggacag taactgacgt tcaggctcga aagcgtgggg agcaaacagg attagatacc 780 ctggtagtcc acgccgtaaa cgatgaatac taggtgtcgg gggacaaagt ctttcggtgc 840 cgccgcaaac gcaataagta ttccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca aatcttgaca tccctctgaa aagcctttaa tcgggctcct ccttcgggac 1020 agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaacccct attgtcagta gccagcaggt aaagctgggc actctgatga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaagag aggcgaagct gtgaggcaga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcggaa atgcccgaag ccagtgaccc aagcgaaagc 1440 agggagctgt cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 16 <211> 986 <212> DNA <213> Clostridium_sp. <220> <221> misc_feature <222> (1) <223> n is a, c, g, or t <400> 16 nccggattta ctgggtgtaa agggtgcgta ggcggaactg caagtcagtg gtgaaatctg 60 agggctcaac cctcaaactg ccattgaaac tgtggttctt gagtgaagta gaggtaggcg 120 gaattcccgg tgtagcggtg gaatgcgtag agatcgggag gaacaccagt ggcgaaggcg 180 gcctactggg ctttaactga cgctgaggca cgaaagcatg ggtagcaaac aggattagat 240 accctggtag tccatgccgt aaacgatgat tactaggtgt ggggggtctg accccctccg 300 tgccggagtt aacacaataa gtaatccacc tggggagtac ggccgcaagg ttgaaactca 360 aaggaattga cgggggcccg cacaagcagt ggagtatgtg gtttaattcg acgcaacgcg 420 aagaacctta ccaggtcttg acatccaact aacgaggtag agatacgtca ggtgcccttc 480 ggggaaagtt gagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 540 taagtcccgc aacgagcgca acccttgtga ttagttgcta cgcaagagca ctctaatcag 600 actgccgttg acaaaacgga ggaaggtggg gatgacgtca aatcatcatg ccctttatga 660 cctgggctac acacgtacta caatggccgt aaacagagag aggcgacacc gcgaggtgaa 720 gcgaaaccct aaaaacggtc tcagttcgga ttgtaggctg caacccgcct acatgaagtt 780 ggaattgcta gtaatcgcgg atcagcatgc cgcggtgaat acgttcccgg gccttgtaca 840 caccgcccgt cacaccatgg gagccggtaa tacccgaagt cagtagtcta accgcaaggg 900 gggcgctgcc gaaggtagga ttggcgactg gggtgaagtc gtaacaaggt agccgtatcg 960 gaaggtgcgg ctggatcacc tccttt 986 <210> 17 <211> 1081 <212> DNA <213> Clostridium_sp. <220> <221> misc_feature <222> (660) <223> n is a, c, g, or t <400> 17 acggcccaga ctcctacggg aggcagcagt ggggaatatt gcgcaatggg ggaaaccctg 60 acgcagcaac gccgcgtgat tgaagaaggc cttcgggttg taaagatctt taattaggga 120 cgaaataaat gacggtacct gaagaataag ctccggctaa ctacgtgcca gcagccgcgg 180 taatacgtag ggagcaagcg ttatccggat ttactgggtg taaagggcgc gcaggcgggc 240 cggtaagttg gaagtgaaat ctatgggctt aacccataaa ctgctttcaa aactgctggt 300 cttgagtgat ggagaggcag gcggaattcc gtgtgtagcg gtgaaatgcg tagatatacg 360 gaggaacacc agtggcgaag gcggcctgct ggacattaac tgacgctgag gcgcgaaagc 420 gtggggagca aacaggatta gataccctgg tagtccacgc cgtaaacgat ggatactagg 480 tgtgggaggt attgacccct tccgtgccgc agttaacaca ataagtatcc cacctgggga 540 gtacggccgc aaggttgaaa ctcaaaggaa ttgacggggg cccgcacaag cagtggagta 600 tgtggtttaa ttcgaagcaa cgcgaagaac cttaccaggt cttgacatcc cgatgaccgn 660 cttttcttcg gaacatcggt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga 720 tgttgggtta agtcccgcaa cgagcgcaac ccttacggtt agttgatacg caagatcact 780 ctagccggac tgccgttgac aaaacggagg aaggtgggga cgacgtcaaa tcatcatgcc 840 ccttatgacc tgggctacac acgtactaca atggcagtca tacagaggga agcaaaaccg 900 cgaggtggag caaatcccta aaagctgtcc cagttcagat tgcaggctgc aacccgcctg 960 catgaagtcg gaattgctag taatcgcgga tcagcatgcc gcggtgaata cgttcccggg 1020 ccttgtacac accgcccgtc acaccatgag agccgtcaat acccgaagtc cgtagcctaa 1080 c 1081 <210> 18 <211> 1526 <212> DNA <213> Clostridium_sp. <400> 18 tttagagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaac acatgcaagt 60 cgaacggggt tattttggaa atctcttcgg agatggaatt cttaacctag tggcggacgg 120 gtgagtaacg cgtgagcaat ctgcctttag gagggggata acagtcggaa acggctgcta 180 ataccgcata atacgtttgg gaggcatctc ttgaacgtca aagattttat cgcctttaga 240 tgagctcgcg tctgattagc tggttggcgg ggtaacggcc caccaaggcg acgatcagta 300 gccggactga gaggttgaac ggccacattg ggactgagac acggcccaga ctcctacggg 360 aggcagcagt ggggaatatt gcgcaatggg ggaaaccctg acgcagcaac gccgcgtgat 420 tgaagaaggc cttcgggttg taaagatctt taatcaggga cgaaaaatga cggtacctga 480 agaataagct ccggctaact acgtgccagc agccgcggta atacgtaggg agcaagcgtt 540 atccggattt actgggtgta aagggcgcgc aggcgggccg gcaagttggg agtgaaatcc 600 cggggcttaa ccccggaact gctttcaaaa ctgctggtct tgagtgatgg agaggcaggc 660 ggaattccgt gtgtagcggt gaaatgcgta gatatacgga ggaacaccag tggcgaaggc 720 ggcctgctgg acattaactg acgctgaggc gcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatgg atactaggtg tgggaggtat tgaccccttc 840 cgtgccgcag ttaacacaat aagtatccca cctggggagt acggccgcaa ggttgaaact 900 caaaggaatt gacgggggcc cgcacaagca gtggagtatg tggtttaatt cgaagcaacg 960 cgaagaacct taccaggtct tgacatcccg atgaccggcg tagagatacg ccctctcttc 1020 ggagcatcgg tgacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt 1080 aagtcccgca acgagcgcaa cccttacggt tagttgatac gcaagatcac tctagccgga 1140 ctgccgttga caaaacggag gaaggtgggg acgacgtcaa atcatcatgc cccttatgac 1200 ctgggctaca cacgtactac aatggcagtc atacagaggg aagcaatacc gcgaggtgga 1260 gcaaatccct aaaagctgtc ccagttcaga ttgcaggctg caacccgcct gcatgaagtc 1320 ggaattgcta gtaatcgcgg atcagcatgc cgcggtgaat acgttcccgg gccttgtaca 1380 caccgcccgt cacaccatga gagccgtcaa tacccgaagt ccgtagccta accgcaaggg 1440 gggcgcggcc gaaggtaggg gtggtaatta gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 19 <211> 1529 <212> DNA <213> Flavonifractor_sp. <400> 19 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggagt gcccatgaca gaggattcgt ccaatggatt gggttactta gtggcggacg 120 ggtgagtaac gcgtgaggaa cctgcctcgg agtggggaat aacacaacga aagctgtgct 180 aataccgcat gatacagttg ggtcgcatga ctctgactgt caaagattta tcgctctgag 240 atggcctcgc gtctgattag ctagttggtg gggtaacggc ccaccaaggc gacgatcagt 300 agccggactg agaggttgac cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg gcgcaagcct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttctcaggg acgaagcaag tgacggtacc 480 tgaggaataa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc 540 gttatccgga tttactgggt gtaaagggcg tgtaggcggg atcgcaagtc agatgtgaaa 600 actggaggct caacctccag cctgcatttg aaactgtggt tcttgagtac tggagaggca 660 gacggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagtggcgaa 720 ggcggtctgc tggacagcaa ctgacgctga ggcgcgaaag cgtggggagc aaacaggatt 780 agataccctg gtagtccacg ctgtaaacga tggatactag gtgtgggggg tctgaccccc 840 tccgtgccgc agttaacaca ataagtatcc cacctgggga gtacgatcgc aaggttgaaa 900 ctcaaaggaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa ttcgaagcaa 960 cgcgaagaac cttaccaggg cttgacatcc cgaggcccgg cctagagata ggcctttctc 1020 ttcggagacc tcggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg 1080 ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ctacgcaaga gcactctagc 1140 gagactgccg ttgacaaaac ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgtcctgggc cacacacgta ctacaatggt ggttaacaga gggaggcaag accgtgaggt 1260 ggagcaaatc cctaaaagcc atcccagttc ggattgcagg ctgcaacccg cctgcatgaa 1320 gttggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttcc cgggccttgt 1380 acacaccgcc cgtcacacca tgagagtcgg gaacacccga agtccgtagc ctaacagcaa 1440 tgggggcgcg gccgaaggtg ggttcgataa ttggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 20 <211> 1529 <212> DNA <213> Intestinimonas_massiliensis <400> 20 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggaac gccaaggaaa gagttttcgg acaatggaat tggctgttta gtggcggacg 120 ggtgagtaac gcgtgagtaa cctgccttgg agtggggaat aacacagtga aaactgtgct 180 aataccgcat gacatattgg tgtcgcatgg cactgatatc aaagatttat cgctctgaga 240 tggactcgcg tctgattaga tagttggcgg ggtaacggcc caccaagtcg acgatcagta 300 gccggactga gaggttggcc ggccacattg ggactgagac acggcccaga ctcctacggg 360 aggcagcagt ggggaatatt gggcaatggg cgcaagcctg acccagcaac gccgcgtgaa 420 ggaagaaggc tttcgggttg taaacttctt ttaacaggga cgaagtaagt gacggtacct 480 gttgaataag ccacggctaa ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg 540 ttatccggat ttactgggtg taaagggcgt gtaggcggga ctgcaagtca gatgtgaaaa 600 ctatgggctc aacccatagc ctgcatttga aactgtagtt cttgagtgtc ggagaggcaa 660 tcggaattcc gtgtgtagcg gtgaaatgcg tagatatacg gaggaacacc agtggcgaag 720 gcggattgct ggacgataac tgacgctgag gcgcgaaagc gtggggagca aacaggatta 780 gataccctgg tagtccacgc cgtaaacgat ggatactagg tgtggggggt ctgaccccct 840 ccgtgccgca gctaacgcaa taagtatccc acctggggag tacgatcgca aggttgaaac 900 tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccagggc ttgacatcct actaacgaac cagagatgga ttaggtgccc 1020 ttcggggaaa gtagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg 1080 ggttaagtcc cgcaacgagc gcaaccctta ttgttagttg ctacgcaaga gcactctagc 1140 gagactgccg ttgacaaaac ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgtcctgggc cacacacgta ctacaatggc ggttaacaga gggaggcaaa gccgcgaggc 1260 agagcaaacc cctaaaagcc gtcccagttc ggattgcagg ctgaaacccg cctgtatgaa 1320 gtcggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttcc cgggccttgt 1380 acacaccgcc cgtcacacca tgagagtcgg gaacacccga agtccgtagc ctaactgcaa 1440 agggggcgcg gccgaaggtg ggttcgataa ttggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 21 <211> 1522 <212> DNA <213> Clostridium_sp. <400> 21 atggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgcttca cttcggtgaa gagtggcgaa cgggtgagta atacataagt aacctggcat 120 ctacaggggg ataactgatg gaaacgtcag ctaagaccgc ataggtgtag agatcgcatg 180 aactctatat gaaaagtgct acgggactgg tagatgatgg acttatggcg cattagctgg 240 ttggtagggt aacggcctac caaggcgacg atgcgtagcc gacctgagag ggtgaccggc 300 cacactggga ctgagacacg gcccagactc ctacgggagg cagcagtagg gaattttcgg 360 caatggggga aaccctgacc gagcaacgcc gcgtgaagga agaagtaatt cgttatgtaa 420 acttctgtca tagaggaaga acggtggata tagggaatga tatccaagtg acggtactct 480 ataagaaagc cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcgagcgt 540 tatccggaat tattgggcgt aaagagggag caggcggcac taagggtctg tggtgaaaga 600 tcgaagctta acttcggtaa gccatggaaa ccgtagagct agagtgtgtg agaggatcgt 660 ggaattccat gtgtagcggt gaaatgcgta gatatatgga ggaacaccag tggcgaaggc 720 gacgatctgg cgcataactg acgctcagtc ccgaaagcgt ggggagcaaa taggattaga 780 taccctagta gtccacgccg taaacgatga gtactaagtg ttgggtgtca aagctcagtg 840 ctgcagttaa cgcaataagt actccgcctg agtagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atcgatctaa aggctccaga gatggagaga tagctataga 1020 gaagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg 1080 caacgagcgc aacccctgtt gccagttgcc agcattaagt tggggactct ggcgagactg 1140 ccggtgacaa gccggaggaa ggcggggatg acgtcaaatc atcatgcccc ttatgacctg 1200 ggctacacac gtgctacaat ggacagagca gagggaagcg aagccgcgag gtggagcgaa 1260 acccataaaa ctgttctcag ttcggactgc agtctgcaac tcgactgcac gaagatggaa 1320 tcgctagtaa tcgcgaatca gcatgtcgcg gtgaatacgt tctcgggcct tgtacacacc 1380 gcccgtcaca ccatgagagt cggtaacacc cgaagccggt ggcctaaccg caaggaagga 1440 gctgtctaag gtgggactga tgattggggt gaagtcgtaa caaggtatcc ctacgggaac 1500 gtggggatgg atcacctcct tt 1522 <210> 22 <211> 1512 <212> DNA <213> Blautia_faecis <220> <221> misc_feature <222> (194) <223> n is a, c, g, or t <400> 22 tattgagagt ttgatcctgg ctcaggacga acgctggcgg catgcctaac acatgcaagt 60 cgagcgagtt gatctcttcg gagtgaagct agcggcggac gggtgagtaa cacgtgggca 120 acctgcctca tagaggggaa tagcctcccg aaagggagat taataccgca taagattgta 180 gcttcgcatg aagnagcaat taaaggagca atccgctatg agatgggccc gcggcgcatt 240 agctagttgg tgaggtaacg gctcaccaag gcgacgatgc gtagccgacc tgagagggtg 300 atcggccaca ttgggactga gacacggccc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggggaaacc ctgatgcagc aatgccgcgt gagtgatgac ggccttcggg 420 ttgtaaagct ctgtcttcgg ggacgataat gacggtaccc gaggaggaag ccacggctaa 480 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttgtccggat ttactgggcg 540 taaagggagc gtaggcggat ttttaagtga gatgtgaaat acccgggctt aacttgggtg 600 ctgcatttca aactggaagt ctagagtgca ggagaggaga agggaattcc tagtgtagcg 660 gtgaaatgcg tagagattag gaagaacacc agtggcgaag gcgcttctct ggactgtaac 720 tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg tagtccacgc 780 cgtaaacgat gaatactagg tgtaggggtt gtcatgacct ctgtgccgcc gctaacgcat 840 taagtattcc gcctggggag tacggtcgca agattaaaac tcaaaggaat tgacgggggc 900 ccgcacaagc agcggagcat gtggtttaat tcgaagcaac gcgaagaacc ttacctagac 960 ttgacatctc ctgcattacc cttaatcggg gaagtcgctt cggcgacagg aagacaggtg 1020 gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca 1080 acccttattg ttagttgcta ccatttagtt gagcactcta gcgagactgc ccgggttaac 1140 cgggaggaag gtggggatga cgtcaaatca tcatgcccct tatgtctagg gctacacacg 1200 tgctacaatg gcaagtacaa agagaagcaa gaccgcgagg tggagcaaaa ctcaaaaact 1260 tgtctcagtt cggattgtag gctgaaactc gcctacatga agctggagtt gctagtaatc 1320 gcgaatcagc atgtcgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc 1380 atgagagttg gcaataccca aagtgcgtga tctaactcgt aagagaggaa gcgccctaag 1440 gtagggtcag cgattggggt gaagtcgtaa caaggtagcc gtaggagaac ctgcggctgg 1500 atcacctcct tt 1512 <210> 23 <211> 1513 <212> DNA <213> Clostridium_disporicum <400> 23 agtgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgagtga atctccttcg ggagtgaagc tagcggcgga cgggtgagta acacgtgggc 120 aacctgcctc atagagggga atagccttcc gaaaggaaga ttaataccgc ataagattgt 180 agcttcgcat gaagtagcaa ttaaaggagc aatccgctat gagatgggcc cgcggcgcat 240 tagctagttg gtgaggtaac ggctcaccaa ggcgacgatg cgtagccgac ctgagagggt 300 gatcggccac attgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tgggggaaac cctgatgcag caacgccgcg tgagtgatga cggccttcgg 420 gttgtaaagc tctgtcttca gggacgataa tgacggtacc tgaggaggaa gccacggcta 480 actacgtgcc agcagccgcg gtaatacgta ggtggcgagc gttgtccgga tttactgggc 540 gtaaagggag cgtaggcgga cttttaagtg agatgtgaaa tacccgggct caacttgggt 600 gctgcatttc aaactggaag tctagagtgc aggagaggag aatggaattc ctagtgtagc 660 ggtgaaatgc gtagagatta ggaagaacac cagtggcgaa ggcgattctc tggactgtaa 720 ctgacgctga ggctcgaaag cgtggggagc aaacaggatt agataccctg gtagtccacg 780 ccgtaaacga tgaatactag gtgtaggggt tgtcatgacc tctgtgccgc cgctaacgca 840 ttaagtattc cgcctgggga gtacggtcgc aagattaaaa ctcaaaggaa ttgacggggg 900 cccgcacaag cagcggagca tgtggtttaa ttcgaagcaa cgcgaagaac cttacctaga 960 cttgacatct cctgcattac ccttaatcgg ggaagttcct tcgggaacag gaagacaggt 1020 ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1080 aacccttatt gttagttgct accatttagt tgagcactct agcgagactg cccgggttaa 1140 ccgggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgtctag ggctacacac 1200 gtgctacaat ggcaagtaca aagagaagca agaccgcgag gtggagcaaa actcaaaaac 1260 ttgtctcagt tcggattgta ggctgaaact cgcctacatg aagctggagt tgctagtaat 1320 cgcgaatcag catgtcgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac 1380 catgagagtt ggcaataccc aaagtgcgtg atctgactcg caagagagga agcgccctaa 1440 ggtagggtca gcgattgggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1500 gatcacctcc ttt 1513 <210> 24 <211> 1511 <212> DNA <213> Anaerostipes_sp. <400> 24 atgagagttc gatcctggct caggataaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagttt ttctttcggg aggaacttag tggcggacgg gtgagtaacg cgtgggtaac 120 ctgccctgta cagggggaca acagctggaa acggctgcta ataccgcata agcccttagc 180 actgcatggt gcatagggaa aaggagcaat ccggtacagg atggacccgc gtctgattag 240 ccagttggca gggtaacggc ctaccaaagc gacgatcagt agccgatctg agaggatgta 300 cggccacatt gggactgaga cacggcccag actcctacgg gaggcagcag tggggaatat 360 tgcacaatgg aggaaactct gatgcagcga cgccgcgtga gtgaagaagt atttcggtat 420 gtaaagctct atcagcaggg aagaaaatga cggtacctga ctaagaagca ccggctaaat 480 acgtgccagc agccgcggta atacgtatgg tgcaagcgtt atccggattt actgggtgta 540 aagggagcgt aggtggcaag gcaagccaga agtgaaaacc cggggctcaa ccgcgggatt 600 gcttttggaa ctgtcatgct agagtgcagg aggggtgagc ggaattccta gtgtagcggt 660 gaaatgcgta gatattagga ggaacaccgg aggcgaaggc ggctcactgg actgtaactg 720 acactgaggc tcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgcgg 780 taaacgatga atactagatg tcgggtagca aagctactcg gtgtcgtcgc aaacgcaata 840 agtattccac ctggggagta cgttcgcaag aatgaaactc aaaggaattg acggggaccc 900 gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctgctctt 960 gacatcccat tcgatagagg gtaatgcctc tagcccttcg ggggaatgga gacaggtggt 1020 gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac 1080 ccttattgtc agtagccagc aggtgaagct gggcactctg atgagactgc cggggataac 1140 ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgagcagg gctacacacg 1200 tgctacaatg gcgtaaacag agggaagcga aggagtgatc cggagcaaat ctcaaaaata 1260 acgtctcagt tcggattgta gtctgcaact cgactacatg aagctggaat cgctagtaat 1320 cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt gtacacaccg cccgtcacac 1380 catgggagtc ggtaatgccc gaagtcagtg actcaaccga aaggagagag ctgccgaagg 1440 caggactggt aactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga 1500 tcacctcctt t 1511 <210> 25 <211> 1513 <212> DNA <213> Ruminococcus_bicirculans <400> 25 tttagagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaac acatgcaagt 60 cgaacggagc ttgaggggct tgcccttcaa gcttagtggc ggacgggtga gtaacgcgtg 120 agtaacctgc ctctcagagg gggataacgt tctgaaaagg acgctaatac cgcatgacat 180 cccggggccg catggccctg ggatcaaagg agcaatccgc tgagagatgg actcgcgtcc 240 gattagctag ttggtgagat aaaggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 ggatattgca caatggaggg aactctgatg cagcaacgcc gcgtgaggga agaaggtctt 420 cggattgtaa acctttgtcc tcagggaaga taatgacggt acctgaggag gaagctccgg 480 ctaactacgt gccagcagcc gcggtaatac gtagggagca agcgttgtcc ggatttactg 540 ggtgtaaagg gtgcgtaggc ggaactgcaa gtcagtggtg aaatctgagg gctcaaccct 600 caaactgcca ttgaaactgt ggttcttgag tgaagtagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagaga tcgggaggaa caccagtggc gaaggcggcc tactgggctt 720 taactgacgc tgaggcacga aagcatgggt agcaaacagg attagatacc ctggtagtcc 780 atgccgtaaa cgatgattac taggtgtggg gggtctgacc ccctccgtgc cggagttaac 840 acaataagta atccacctgg ggagtacggc cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 ggtcttgaca tccaactaac gaggtagaga tacgtcaggt gcccttcggg gaaagttgag 1020 acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac 1080 gagcgcaacc cttgtgatta gttgctacgc aagagcactc taatcagact gccgttgaca 1140 aaacggagga aggtggggat gacgtcaaat catcatgccc tttatgacct gggctacaca 1200 cgtactacaa tggccgtaaa cagagagagg cgacaccgcg aggtgaagcg aaaccctaaa 1260 aacggtctca gttcggattg taggctgcaa cccgcctaca tgaagttgga attgctagta 1320 atcgcggatc agcatgccgc ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac 1380 accatgggag ccggtaatac ccgaagtcag tagtctaacc gcaagggggg cgctgccgaa 1440 ggtaggattg gcgactgggg tgaagtcgta acaaggtagc cgtatcggaa ggtgcggctg 1500 gatcacctcc ttt 1513 <210> 26 <211> 1511 <212> DNA <213> Ruminococcus_bicirculans <400> 26 attaagagtt tgatcctggc tcaggacgaa cgctggcggc acgcttaaca catgcaagtc 60 gaacgagaga agagaagctt gcttttctga tctagtggcg gacgggtgag taacacgtga 120 gcaatctgcc tttcagaggg ggataccgat tggaaacgat cgttaatacc gcataacata 180 attgaaccgc atgatttgat tatcaaagat ttatcgctga aagatgagct cgcgtctgat 240 tagctagttg gtaaggtaac ggcttaccaa ggcgacgatc agtagccgga ctgagaggtt 300 gatcggccac attgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tggaggaaac tctgatgcag cgatgccgcg tgagggaaga aggttttagg 420 attgtaaacc tctgtcttca gggacgaaaa aaaagacggt acctgaggag gaagctccgg 480 ctaactacgt gccagcagcc gcggtaatac gtagggagcg agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgtaggc gggatcgcaa gtcagatgtg aaaactatgg gcttaaccca 600 taaactgcat ttgaaactgt ggttcttgag tgaagtagag gtaagcggaa ttcctagtgt 660 agcggtgaaa tgcgtagata ttaggaggaa catcagtggc gaaggcggct tactgggctt 720 taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc ctggtagtcc 780 acgccgtaaa cgatgattac taggtgtggg gggactgacc ccttccgtgc cgcagcaaac 840 gcaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggat taattcgaag caacgcgaag aaccttacca 960 ggtcttgaca tcgtatgcat agctcagaga tgagtgaaat ctcttcggag acatatagac 1020 aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga 1080 gcgcaaccct tactgttagt tgctacgcaa gagcactcta gcaggactgc cgttgacaaa 1140 acggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg gcctcacacg 1200 tactacaatg gctgtcaaca gagggatgca aagccgcgag gtggagcgaa cccctaaaag 1260 cagtcttagt tcggattgta ggctgcaacc cgcctacatg aagtcggaat tgctagtaat 1320 cgcagatcag catgctgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacgc 1380 catgggagtc ggtaacaccc gaagcctgta gtctaaccgc aaggaggacg cagtcgaagg 1440 tgggattgat gactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga 1500 tcacctcctt t 1511 <210> 27 <211> 1553 <212> DNA <213> Streptococcus gordonii <400> 27 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgcacag tttataccgt agcttgctac accatagact gtgagttgcg aacgggtgag 120 taacgcgtag gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc 180 gcataatatt aattattgca tgataattga ttgaaagatg caactgcatc actaccagat 240 ggacctgcgt tgtattagct agtaggtgag gtaacggctc acctaggcga cgatacatag 300 ccgacctgag agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga 360 ggcagcagta gggaatcttc ggcaatggac gaaagtctga ccgagcaacg ccgcgtgagt 420 gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa gaacgggtgt gagagtggaa 480 agttcacact gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc 540 ggtaatacgt aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg 600 ttagataagt ctgaagttaa aggctgtggc ttaaccatag tacgctttgg aaactgttta 660 acttgagtgc agaaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat 720 ggaggaacac cggtggcgaa agcggctctc tggtctgtaa ctgacgctga ggctcgaaag 780 cgtggggagc gaacaggatt agataccctg gtagtccacg ccgtaaacga tgagtgctag 840 gtgttaggcc ctttccgggg cttagtgccg cagctaacgc attaagcact ccgcctgggg 900 agtacgaccg caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc 960 atgtggttta attcgaagca acgcgaagaa ccttaccagg tcttgacatc ccgatgcccg 1020 ctctagagat agagttttac ttcggtacat cggtgacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttat tgttagttgc 1140 catcattcag ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat 1200 gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac 1260 aacgagtcgc aagtcggtga cggcaagcta atctcttaaa gccagtctca gttcggattg 1320 taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc 1380 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac 1440 ccgaagtcgg tgaggtaacc ttttaggagc cagccgccta aggtgggata gatgattggg 1500 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1553 <210> 28 <211> 1553 <212> DNA <213> Streptococcus gordonii <400> 28 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgcacag tttataccgt agcttgctac accatagact gtgagttgcg aacgggtgag 120 taacgcgtag gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc 180 gcataatatt aattattgca tgataattga ttgaaagatg caactgcatc actaccagat 240 ggacctgcgt tgtattagct agtaggtgag gtaacggctc acctaggcga cgatacatag 300 ccgacctgag agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga 360 ggcagcagta gggaatcttc ggcaatggac gaaagtctga ccgagcaacg ccgcgtgagt 420 gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa gaacgggtgt gagagtggaa 480 agttcacact gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc 540 ggtaatacgt aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg 600 ttagataagt ctgaagttaa aggctgtggc ttaaccatag tacgctttgg aaactgttta 660 acttgagtgc agaaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat 720 ggaggaacac cggtggcgaa agcggctctc tggtctgtaa ctgacgctga ggctcgaaag 780 cgtggggagc gaacaggatt agataccctg gtagtccacg ccgtaaacga tgagtgctag 840 gtgttaggcc ctttccgggg cttagtgccg cagctaacgc attaagcact ccgcctgggg 900 agtacgaccg caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc 960 atgtggttta attcgaagca acgcgaagaa ccttaccagg tcttgacatc ccgatgcccg 1020 ctctagagat agagttttac ttcggtacat cggtgacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttat tgttagttgc 1140 catcattcag ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat 1200 gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac 1260 aacgagtcgc aagtcggtga cggcaagcta atctcttaaa gccagtctca gttcggattg 1320 taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc 1380 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac 1440 ccgaagtcgg tgaggtaacc ttttaggagc cagccgccta aggtgggata gatgattggg 1500 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1553 <210> 29 <211> 1553 <212> DNA <213> Streptococcus gordonii <400> 29 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgcacag tttataccgt agcttgctac accatagact gtgagttgcg aacgggtgag 120 taacgcgtag gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc 180 gcataatatt aattattgca tgataattga ttgaaagatg caactgcatc actaccagat 240 ggacctgcgt tgtattagct agtaggtgag gtaacggctc acctaggcga cgatacatag 300 ccgacctgag agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga 360 ggcagcagta gggaatcttc ggcaatggac gaaagtctga ccgagcaacg ccgcgtgagt 420 gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa gaacgggtgt gagagtggaa 480 agttcacact gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc 540 ggtaatacgt aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg 600 ttagataagt ctgaagttaa aggctgtggc ttaaccatag tacgctttgg aaactgttta 660 acttgagtgc agaaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat 720 ggaggaacac cggtggcgaa agcggctctc tggtctgtaa ctgacgctga ggctcgaaag 780 cgtggggagc gaacaggatt agataccctg gtagtccacg ccgtaaacga tgagtgctag 840 gtgttaggcc ctttccgggg cttagtgccg cagctaacgc attaagcact ccgcctgggg 900 agtacgaccg caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc 960 atgtggttta attcgaagca acgcgaagaa ccttaccagg tcttgacatc ccgatgcccg 1020 ctctagagat agagttttac ttcggtacat cggtgacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttat tgttagttgc 1140 catcattcag ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat 1200 gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac 1260 aacgagtcgc aagtcggtga cggcaagcta atctcttaaa gccagtctca gttcggattg 1320 taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc 1380 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac 1440 ccgaagtcgg tgaggtaacc ttttaggagc cagccgccta aggtgggata gatgattggg 1500 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1553 <210> 30 <211> 1553 <212> DNA <213> Streptococcus gordonii <400> 30 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgcacag tttataccgt agcttgctac accataaact gtgagttgcg aacgggtgag 120 taacgcgtag gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc 180 gcataatatt gattattgca tgataattga ttgaaagatg ctattgcatc actaccagat 240 ggacctgcgt tgtattagct agtaggtgag gtaacggctc acctaggcga cgatacatag 300 ccgacctgag agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga 360 ggcagcagta gggaatcttc ggcaatggac gaaagtctga ccgagcaacg ccgcgtgagt 420 gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa gaacgggtgt gagagtggaa 480 agttcacact gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc 540 ggtaatacgt aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg 600 ttagataagt ctgaagttaa aggctgtggc ttaaccatag tacgctttgg aaactgttta 660 acttgagtgc agaaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat 720 ggaggaacac cggtggcgaa agcggctctc tggtctgtaa ctgacgctga ggctcgaaag 780 cgtggggagc gaacaggatt agataccctg gtagtccacg ccgtaaacga tgagtgctag 840 gtgttaggcc ctttccgggg cttagtgccg cagctaacgc attaagcact ccgcctgggg 900 agtacgaccg caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc 960 atgtggttta attcgaagca acgcgaagaa ccttaccagg tcttgacatc ccgatgcccg 1020 ctctagagat agagttttac ttcggtacat cggtgacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttat tgttagttgc 1140 catcattcag ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat 1200 gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac 1260 aacgagtcgc aagtcggtga cggcaagcta atctcttaaa gccagtctca gttcggattg 1320 taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc 1380 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac 1440 ccgaagtcgg tgaggtaacc ttttaggagc cagccgccta aggtgggata gatgattggg 1500 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1553 <210> 31 <211> 1509 <212> DNA <213> Akkermansia_muciniphila <400> 31 atggagagtt tgattctggc tcagaacgaa cgctggcggc gtggataaga catgcaagtc 60 gaacgagaga attgctagct tgctaataat tctctagtgg cgcacgggtg agtaacacgt 120 gagtaacctg cccccgagag cgggatagcc ctgggaaact gggattaata ccgcatagta 180 tcgaaagatt aaagcagcaa tgcgcttggg gatgggctcg cggcctatta gttagttggt 240 gaggtaacgg ctcaccaagg cgatgacggg tagccggtct gagaggatgt ccggccacac 300 tggaactgag acacggtcca gacacctacg ggtggcagca gtcgagaatc attcacaatg 360 ggggaaaccc tgatggtgcg acgccgcgtg ggggaatgaa ggtcttcgga ttgtaaaccc 420 ctgtcatgtg ggagcaaatt aaaaagatag taccacaaga ggaagagacg gctaactctg 480 tgccagcagc cgcggtaata cagaggtctc aagcgttgtt cggaatcact gggcgtaaag 540 cgtgcgtagg ctgtttcgta agtcgtgtgt gaaaggcgcg ggctcaaccc gcggacggca 600 catgatactg cgagactaga gtaatggagg gggaaccgga attctcggtg tagcagtgaa 660 atgcgtagat atcgagagga acactcgtgg cgaaggcggg ttcctggaca ttaactgacg 720 ctgaggcacg aaggccaggg gagcgaaagg gattagatac ccctgtagtc ctggcagtaa 780 acggtgcacg cttggtgtgc ggggaatcga ccccctgcgt gccggagcta acgcgttaag 840 cgtgccgcct ggggagtacg gtcgcaagat taaaactcaa agaaattgac ggggacccgc 900 acaagcggtg gagtatgtgg cttaattcga tgcaacgcga agaaccttac ctgggcttga 960 catgtaatga acaacatgtg aaagcatgcg actcttcgga ggcgttacac aggtgctgca 1020 tggccgtcgt cagctcgtgt cgtgagatgt ttggttaagt ccagcaacga gcgcaacccc 1080 tgttgccagt taccagcacg tgaaggtggg gactctggcg agactgccca gatcaactgg 1140 gaggaaggtg gggacgacgt caggtcagta tggcccttat gcccagggct gcacacgtac 1200 tacaatgccc agtacagagg gggccgaagc cgcgaggcgg aggaaatcct aaaaactggg 1260 cccagttcgg actgtaggct gcaacccgcc tacacgaagc cggaatcgct agtaatggcg 1320 catcagctac ggcgccgtga atacgttccc gggtcttgta cacaccgccc gtcacatcat 1380 ggaagccggt cgcacccgaa gtatctgaag ccaaccgcaa ggaggcaggg tcctaaggtg 1440 agactggtaa ctgggatgaa gtcgtaacaa ggtagccgta ggggaacctg cggctggatc 1500 acctccttt 1509 <210> 32 <211> 1509 <212> DNA <213> Akkermansia_muciniphila <400> 32 atggagagtt tgattctggc tcagaacgaa cgctggcggc gtggataaga catgcaagtc 60 gaacgagaga attgctagct tgctaataat tctctagtgg cgcacgggtg agtaacacgt 120 gagtaacctg cccccgagag cgggatagcc ctgggaaact gggattaata ccgcatagta 180 tcgaaagatt aaagcagcaa tgcgcttggg gatgggctcg cggcctatta gttagttggt 240 gaggtaacgg ctcaccaagg cgatgacggg tagccggtct gagaggatgt ccggccacac 300 tggaactgag acacggtcca gacacctacg ggtggcagca gtcgagaatc attcacaatg 360 ggggaaaccc tgatggtgcg acgccgcgtg ggggaatgaa ggtcttcgga ttgtaaaccc 420 ctgtcatgtg ggagcaaatt aaaaagatag taccacaaga ggaagagacg gctaactctg 480 tgccagcagc cgcggtaata cagaggtctc aagcgttgtt cggaatcact gggcgtaaag 540 cgtgcgtagg ctgtttcgta agtcgtgtgt gaaaggcgcg ggctcaaccc gcggacggca 600 catgatactg cgagactaga gtaatggagg gggaaccgga attctcggtg tagcagtgaa 660 atgcgtagat atcgagagga acactcgtgg cgaaggcggg ttcctggaca ttaactgacg 720 ctgaggcacg aaggccaggg gagcgaaagg gattagatac ccctgtagtc ctggcagtaa 780 acggtgcacg cttggtgtgc ggggaatcga ccccctgcgt gccggagcta acgcgttaag 840 cgtgccgcct ggggagtacg gtcgcaagat taaaactcaa agaaattgac ggggacccgc 900 acaagcggtg gagtatgtgg cttaattcga tgcaacgcga agaaccttac ctgggcttga 960 catgtaatga acaacatgtg aaagcatgcg actcttcgga ggcgttacac aggtgctgca 1020 tggccgtcgt cagctcgtgt cgtgagatgt ttggttaagt ccagcaacga gcgcaacccc 1080 tgttgccagt taccagcacg tgaaggtggg gactctggcg agactgccca gatcaactgg 1140 gaggaaggtg gggacgacgt caggtcagta tggcccttat gcccagggct gcacacgtac 1200 tacaatgccc agtacagagg gggccgaagc cgcgaggcgg aggaaatcct aaaaactggg 1260 cccagttcgg actgtaggct gcaacccgcc tacacgaagc cggaatcgct agtaatggcg 1320 catcagctac ggcgccgtga atacgttccc gggtcttgta cacaccgccc gtcacatcat 1380 ggaagccggt cgcacccgaa gtatctgaag ccaaccgcaa ggaggcaggg tcctaaggtg 1440 agactggtaa ctgggatgaa gtcgtaacaa ggtagccgta ggggaacctg cggctggatc 1500 acctccttt 1509 <210> 33 <211> 1509 <212> DNA <213> Akkermansia_muciniphila <400> 33 atggagagtt tgattctggc tcagaacgaa cgctggcggc gtggataaga catgcaagtc 60 gaacgagaga attgctagct tgctaataat tctctagtgg cgcacgggtg agtaacacgt 120 gagtaacctg cccccgagag cgggatagcc ctgggaaact gggattaata ccgcatagta 180 tcgaaagatt aaagcagcaa tgcgcttggg gatgggctcg cggcctatta gttagttggt 240 gaggtaacgg ctcaccaagg cgatgacggg tagccggtct gagaggatgt ccggccacac 300 tggaactgag acacggtcca gacacctacg ggtggcagca gtcgagaatc attcacaatg 360 ggggaaaccc tgatggtgcg acgccgcgtg ggggaatgaa ggtcttcgga ttgtaaaccc 420 ctgtcatgtg ggagcaaatt aaaaagatag taccacaaga ggaagagacg gctaactctg 480 tgccagcagc cgcggtaata cagaggtctc aagcgttgtt cggaatcact gggcgtaaag 540 cgtgcgtagg ctgtttcgta agtcgtgtgt gaaaggcgcg ggctcaaccc gcggacggca 600 catgatactg cgagactaga gtaatggagg gggaaccgga attctcggtg tagcagtgaa 660 atgcgtagat atcgagagga acactcgtgg cgaaggcggg ttcctggaca ttaactgacg 720 ctgaggcacg aaggccaggg gagcgaaagg gattagatac ccctgtagtc ctggcagtaa 780 acggtgcacg cttggtgtgc ggggaatcga ccccctgcgt gccggagcta acgcgttaag 840 cgtgccgcct ggggagtacg gtcgcaagat taaaactcaa agaaattgac ggggacccgc 900 acaagcggtg gagtatgtgg cttaattcga tgcaacgcga agaaccttac ctgggcttga 960 catgtaatga acaacatgtg aaagcatgcg actcttcgga ggcgttacac aggtgctgca 1020 tggccgtcgt cagctcgtgt cgtgagatgt ttggttaagt ccagcaacga gcgcaacccc 1080 tgttgccagt taccagcacg tgaaggtggg gactctggcg agactgccca gatcaactgg 1140 gaggaaggtg gggacgacgt caggtcagta tggcccttat gcccagggct gcacacgtac 1200 tacaatgccc agtacagagg gggccgaagc cgcgaggcgg aggaaatcct aaaaactggg 1260 cccagttcgg actgtaggct gcaacccgcc tacacgaagc cggaatcgct agtaatggcg 1320 catcagctac ggcgccgtga atacgttccc gggtcttgta cacaccgccc gtcacatcat 1380 ggaagccggt cgcacccgaa gtatctgaag ccaaccgcaa ggaggcaggg tcctaaggtg 1440 agactggtaa ctgggatgaa gtcgtaacaa ggtagccgta ggggaacctg cggctggatc 1500 acctccttt 1509 <210> 34 <211> 1529 <212> DNA <213> Eubacterium rectale <400> 34 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttccttcggg actgattatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccttgt acagggggat aacagttgga aacggctgct 180 aataccgcat aagcgcacgg catcgcatga tgcagtgtga aaaactccgg tggtataaga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggga agataatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtgcgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcgtacta gagtgtcgga ggggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgataactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt tgggaagcat tgcttctcgg 840 tgccgtcgca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccttct gaccggtact taaccgtacc ttctcttcgg 1020 agcaggagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttta gtagccagcg gttcggccgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgacttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcaaag ctgtgaagcc 1260 gagcaaatct caaaaataac gtctcagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg gaatgcccga agccagtgac ctaaccgaaa 1440 ggaaggagct gtcgaaggca ggctcgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 35 <211> 1529 <212> DNA <213> Eubacterium rectale <400> 35 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttccttcggg actgattatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccttgt acagggggat aacagttgga aacggctgct 180 aataccgcat aagcgcacag catcgcatga tgcagtgtga aaaactccgg tggtataaga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggga agataatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtgcgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcgtacta gagtgtcgga ggggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgataactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt tgggaagcat tgcttctcgg 840 tgccgtcgca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccttct gaccggtact taaccgtacc ttctcttcgg 1020 agcaggagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttta gtagccagcg gtccggccgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgacttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcaaag ctgtgaagcc 1260 gagcaaatct caaaaataac gtctcagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg gaatgcccga agccagtgac ctaaccgaaa 1440 ggaaggagct gtcgaaggca ggctcgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 36 <211> 1529 <212> DNA <213> Eubacterium rectale <400> 36 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttccttcggg actgattatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccttgt acagggggat aacagttgga aacggctgct 180 aataccgcat aagcgcacgg catcgcatga tgcagtgtga aaaactccgg tggtataaga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggga agataatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtgcgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcgtacta gagtgtcgga ggggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgataactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccgcgccgt aaacgatgaa tactaggtgt tgggaagcat tgcttctcgg 840 tgccgtcgca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccttct gaccggtact taaccgtacc ttctcttcgg 1020 agcaggagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttta gtagccagcg gtttggccgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgacttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcaaag ctgtgaagcc 1260 gagcaaatct caaaaataac gtctcagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg gaatgcccga agccagtgac ctaaccgaaa 1440 ggaaggagct gtcgaaggca ggctcgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 37 <211> 1529 <212> DNA <213> Eubacterium rectale <400> 37 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttccttcggg actgattatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccttgt acagggggat aacagttgga aacggctgct 180 aataccgcat aagcgcacgg catcgcatga tgcagtgtga aaaactccgg tggtataaga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggga agataatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtgcgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcgtacta gagtgtcgga ggggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgataactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt tgggaagcat tgcttctcgg 840 tgccgtcgca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccttct gaccggtact taaccgtacc ttctcttcgg 1020 agcaggagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttta gtagccagcg gttcggccgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgacttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcaaag ctgtgaagcc 1260 gagcaaatct caaaaataac gtctcagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg gaatgcccga agccagtgac ctaaccgaaa 1440 ggaaggagct gtcgaaggca ggctcgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 38 <211> 1529 <212> DNA <213> Eubacterium rectale <400> 38 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttccttcggg actgattatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccttgt acagggggat aacagttgga aacggctgct 180 aataccgcat aagcgcacag catcgcatga tgcagtgtga aaaactccgg tggtataaga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggga agataatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtgcgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcgtacta gagtgtcgga ggggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgataactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgctgt aaacgatgaa tactaggtgt tgggaagcat tgcttctcgg 840 tgccgtcgca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccttct gaccggtact taaccgtacc ttctcttcgg 1020 agcaggagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttatcttta gtagccagcg gtctggccgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgacttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcgaag ctgtgaagcc 1260 gagcaaatct caaaaataac gtctcagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagttgg gaatgcccga agccagtgac ctaaccgaaa 1440 ggaaggagct gtcgaaggca ggctcgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 39 <211> 1506 <212> DNA <213> Eggerthella_lenta <400> 39 acggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgatgaa accgccctcg ggcggacatg aagtggcgaa cgggtgagta acacgtgacc 120 aacctgcccc ttgctccggg acaaccttgg gaaaccgagg ctaataccgg atactcctcg 180 cccccctcct ggggggcccg ggaaagccca gacggcaagg gatggggtcg cggcccatta 240 ggtagtaggc ggggtaacgg cccacctagc ccgcgatggg tagccgggtt gagagaccga 300 ccggccacat tgggactgag atacggccca gactcctacg ggaggcagca gtggggaatt 360 ttgcgcaatg ggggaaaccc tgacgcagca acgccgcgtg cgggacgacg gccttcgggt 420 tgtaaaccgc tttcagcagg gaagaaattc gacggtacct gcagaagaag ctccggctaa 480 ctacgtgcca gcagccgcgg taatacgtag ggagcgagcg ttatccggat tcattgggcg 540 taaagagcgc gtaggcggcc tctcaagcgg gatctctaat ccgagggctc aacccccggc 600 cggatcccga actgggaggc tcgagttcgg tagaggcagg cggaattccc ggtgtagcgg 660 tggaatgcgc agatatcggg aagaacaccg atggcgaagg cagcctgctg ggccgcaact 720 gacgctgagg cgcgaaagct aggggagcga acaggattag ataccctggt agtcctagcc 780 gtaaacgatg gatactaggt gtggggggct ccgccctccg tgccgcagcc aacgcattaa 840 gtatcccgcc tggggagtac ggccgcaagg ctaaaactca aaggaattga cgggggcccg 900 cacaagcagc ggagcatgtg gcttaattcg aagcaacgcg aagaacctta ccagggcttg 960 acatggacgt gaagccgggg aaacccggtg gccgagagga gcgtccgcag gtggtgcatg 1020 gctgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaacccctg 1080 ccccatgttg ccagcattag gttggggact catgggggac tgccggcgtc aagccggagg 1140 aaggtgggga cgacgtcaag tcatcatgcc ctttatgccc tgggctgcac acgtgctaca 1200 atggccggta caacgggctg cgagaccgcg aggtcgagcg aatccctcaa agccggcccc 1260 agttcggatc ggaggctgca acccgcctcc gtgaagtcgg agttgctagt aatcgcggat 1320 cagcatgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacccga 1380 gtcgtctgca cccgaagccg ccggccgaac ccgcaagggg cggaggcgtc gaaggtgtgg 1440 agggtaaggg gggtgaagtc gtaacaaggt agccgtaccg gaaggtgcgg ctggatcacc 1500 tccttt 1506 <210> 40 <211> 1506 <212> DNA <213> Eggerthella_lenta <400> 40 acggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgatgaa accgccctcg ggcggacatg aagtggcgaa cgggtgagta acacgtgacc 120 aacctgcccc ttgctccggg acaaccttgg gaaaccgagg ctaataccgg atactcctcg 180 cccccctcct ggggggcccg ggaaagccca gacggcaagg gatggggtcg cggcccatta 240 ggtagtaggc ggggtaacgg cccacctagc ccgcgatggg tagccgggtt gagagaccga 300 ccggccacat tgggactgag atacggccca gactcctacg ggaggcagca gtggggaatt 360 ttgcgcaatg ggggaaaccc tgacgcagca acgccgcgtg cgggacgacg gccttcgggt 420 tgtaaaccgc tttcagcagg gaagaaattc gacggtacct gcagaagaag ctccggctaa 480 ctacgtgcca gcagccgcgg taatacgtag ggagcgagcg ttatccggat tcattgggcg 540 taaagagcgc gtaggcggcc tctcaagcgg gatctctaat ccgagggctc aacccccggc 600 cggatcccga actgggaggc tcgagttcgg tagaggcagg cggaattccc ggtgtagcgg 660 tggaatgcgc agatatcggg aagaacaccg atggcgaagg cagcctgctg ggccgcaact 720 gacgctgagg cgcgaaagct aggggagcga acaggattag ataccctggt agtcctagcc 780 gtaaacgatg gatactaggt gtggggggct ccgccctccg tgccgcagcc aacgcattaa 840 gtatcccgcc tggggagtac ggccgcaagg ctaaaactca aaggaattga cgggggcccg 900 cacaagcagc ggagcatgtg gcttaattcg aagcaacgcg aagaacctta ccagggcttg 960 acatggacgt gaagccgggg aaacccggtg gccgagagga gcgtccgcag gtggtgcatg 1020 gctgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaacccctg 1080 ccccatgttg ccagcattag gttggggact catgggggac tgccggcgtc aagccggagg 1140 aaggtgggga cgacgtcaag tcatcatgcc ctttatgccc tgggctgcac acgtgctaca 1200 atggccggta caacgggctg cgagaccgcg aggtcgagcg aatccctcaa agccggcccc 1260 agttcggatc ggaggctgca acccgcctcc gtgaagtcgg agttgctagt aatcgcggat 1320 cagcatgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacccga 1380 gtcgtctgca cccgaagccg ccggccgaac ccgcaagggg cggaggcgtc gaaggtgtgg 1440 agggtaaggg gggtgaagtc gtaacaaggt agccgtaccg gaaggtgcgg ctggatcacc 1500 tccttt 1506 <210> 41 <211> 1506 <212> DNA <213> Eggerthella_lenta <400> 41 acggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgatgaa accgccctcg ggcggacatg aagtggcgaa cgggtgagta acacgtgacc 120 aacctgcccc ttgctccggg acaaccttgg gaaaccgagg ctaataccgg atactcctcg 180 cccccctcct ggggggcccg ggaaagccca gacggcaagg gatggggtcg cggcccatta 240 ggtagtaggc ggggtaacgg cccacctagc ccgcgatggg tagccgggtt gagagaccga 300 ccggccacat tgggactgag atacggccca gactcctacg ggaggcagca gtggggaatt 360 ttgcgcaatg ggggaaaccc tgacgcagca acgccgcgtg cgggacgacg gccttcgggt 420 tgtaaaccgc tttcagcagg gaagaaattc gacggtacct gcagaagaag ctccggctaa 480 ctacgtgcca gcagccgcgg taatacgtag ggagcgagcg ttatccggat tcattgggcg 540 taaagagcgc gtaggcggcc tctcaagcgg gatctctaat ccgagggctc aacccccggc 600 cggatcccga actgggaggc tcgagttcgg tagaggcagg cggaattccc ggtgtagcgg 660 tggaatgcgc agatatcggg aagaacaccg atggcgaagg cagcctgctg ggccgcaact 720 gacgctgagg cgcgaaagct aggggagcga acaggattag ataccctggt agtcctagcc 780 gtaaacgatg gatactaggt gtggggggct ccgccctccg tgccgcagcc aacgcattaa 840 gtatcccgcc tggggagtac ggccgcaagg ctaaaactca aaggaattga cgggggcccg 900 cacaagcagc ggagcatgtg gcttaattcg aagcaacgcg aagaacctta ccagggcttg 960 acatggacgt gaagccgggg aaacccggtg gccgagagga gcgtccgcag gtggtgcatg 1020 gctgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaacccctg 1080 ccccatgttg ccagcattag gttggggact catgggggac tgccggcgtc aagccggagg 1140 aaggtgggga cgacgtcaag tcatcatgcc ctttatgccc tgggctgcac acgtgctaca 1200 atggccggta caacgggctg cgagaccgcg aggtcgagcg aatccctcaa agccggcccc 1260 agttcggatc ggaggctgca acccgcctcc gtgaagtcgg agttgctagt aatcgcggat 1320 cagcatgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacccga 1380 gtcgtctgca cccgaagccg ccggccgaac ccgcaagggg cggaggcgtc gaaggtgtgg 1440 agggtaaggg gggtgaagtc gtaacaaggt agccgtaccg gaaggtgcgg ctggatcacc 1500 tccttt 1506 <210> 42 <211> 1535 <212> DNA <213> Burkholderiales_bacterium_1_1_47 <400> 42 atagagtttg atcctggctc agattgaacg ctggcggaac gctttacaca tgcaagtcga 60 acggtaacgc gggagaagct tgcttctccc ggcgacgagt ggcgaacggg tgagtaatac 120 atcggaacgt gtccgctcgt gggggacaac cagccgaaag gttggctaat accgcatgag 180 ttctacggaa gaaagagggg gacccgcaag ggcctctcgc gagcggagcg gccgatgact 240 gattagccgg ttggtgaggt aacggctcac caaagcaacg atcagtagct ggtctgagag 300 gacgaccagc cacactggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaattttgga caatgggcgc aagcctgatc cagctattcc gcgtgtggga tgaaggccct 420 cgggttgtaa accacttttg tagagaacga aaagacacct tcgaataaag ggtgttgctg 480 acggtactct aagaataagc accggctaac tacgtgccag cagccgcggt aatacgtagg 540 gtgcgagcgt taatcggaat tactgggcgt aaagggtgcg caggcggttg agtaagacag 600 atgtgaaatc cccgagctta actcgggaat ggcatatgtg actgctcgac tagagtgtgt 660 cagagggagg tggaattcca cgtgtagcag tgaaatgcgt agatatgtgg aagaacaccg 720 atggcgaagg cagcctcctg ggacataact gacgctcagg cacgaaagcg tggggagcaa 780 acaggattag ataccctggt agtccacgcc ctaaacgatg ttaactagtt gttgggaagt 840 aaaattctca gtaacgcagc caacgcgaga agttaaccgc ctgggaagta cggtcgcaag 900 actaaaactc aaaggaattg acggggaccc gcacaagcgg tggatgatgt ggattaattc 960 gatgcaacgc gaaaaacctt acctaccctt gacatgtcag gaagctcttg taatgagagt 1020 gtgcccgcaa gggagcctga acacaggtgc tgcatggctg tcgtcagctc gtgtcgtgag 1080 atgttgggtt aagtcccgca acgagcgcaa cccttgtcac tagttgctac gaaagggcac 1140 tctagtgaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa gtcctcatgg 1200 cccttatggg tagggcttca cacgtcatac aatggtcgga acagagggca gcgaagtcgt 1260 gagacggagc caatcccaga aaaccgatcg tagtccggat tgcagtctgc aactcgactg 1320 catgaagtcg gaatcgctag taatcgcgga tcagcatgcc gcggtgaata cgttcccggg 1380 tcttgtacac accgcccgtc aaacaatggg agtggtgttt accagaagtc gttagcctaa 1440 ccgcaaggag ggcggcgacc acggtgagca ccgtgactaa tgttaagtcg taacaaggta 1500 gccgtaccgg aaggtgcggc tggatcacct ccttt 1535 <210> 43 <211> 1529 <212> DNA <213> Eubacterium eligens <400> 43 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttagaaca gattacttcg gtttgaagtt ctttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctt gtactggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac aatgttgcat gacatggtgt gaaaaactcc ggtggtataa 240 gatggacccg cgtctgatta gctagttggt gagataacag cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca tgcaagtcag aagtgaaaat 600 ccggggctca accccggaac tgcttttgaa actgtaaggc tggagtgcag gaggggtgag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctcactg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccc ataagggctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatcct cttgaccggt cagtaatgtg gcctttcctt 1020 cgggacaaga gagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctatcc ttagtagcca gcagtaagat gggcactcta 1140 gggagactgc cagggataac ctggaggaag gtggggatga cgtcaaatca tcatgcccct 1200 tatgacttgg gctacacacg tgctacaatg gcgtaaacaa agtgaagcga agtcgtgagg 1260 ccaagcaaat cacaaaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtc gaaaatgccc gaagtcggtg acctaacgta 1440 agaaggagcc gccgaaggca ggtttgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 44 <211> 1530 <212> DNA <213> Eubacterium eligens <400> 44 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttagaaca gattatttcg gtatgaagtt ctttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctt gtactggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac aatgttgcat gacatggtgt gaaaaactcc ggtggtataa 240 gatggacccg cgtctgatta gctagttggt gagataacag cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca tgcaagtcag aagtgaaaat 600 ccggggctca accccggaac tgcttttgaa actgtaaggc tggagtgcag gaggggtgag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctcactg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccc aaaagggctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaaac cttaccaagt cttgacatcc cactgaccgg acagtaatgt gtcctttcct 1020 tcgggacagt ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg 1080 ttaagtcccg caacgagcgc aacccctatc cttagtagcc agcagtaaga tgggcactct 1140 agggagactg ccagggataa cctggaggaa ggtggggatg acgtcaaatc atcatgcccc 1200 ttatgacttg ggctacacac gtgctacaat ggcgtaaaca aagtgaagcg aagtcgtgag 1260 gccaagcaaa tcacaaaaat aacgtctcag ttcggattgt agtctgcaac tcgactacat 1320 gaagctggaa tcgctagtaa tcgcagatca gaatgctgcg gtgaatacgt tcccgggtct 1380 tgtacacacc gcccgtcaca ccatgggagt cgaaaatgcc cgaagtcggt gacctaacgt 1440 aagaaggagc cgccgaaggc aggtttgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 45 <211> 1529 <212> DNA <213> Eubacterium eligens <400> 45 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttagaaca gattatttcg gtatgaagtt ctttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctt gtactggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac aatgttgcat gacatagtgt gaaaaactcc ggtggtataa 240 gatggacccg cgtctgatta gctagttggt gagataacag cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca tgcaagtcag aagtgaaaat 600 ccggggctta accccggaac tgcttttgaa actgtaaggc tggagtgcag gaggggtgag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctcactg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccc ataagggctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatccc actgaccgga cagtaatgtg tcctttcctt 1020 cgggacagtg gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctatcc ttagtagcca gcagtaagat gggcactcta 1140 gggagactgc cagggataac ctggaggaag gtggggatga cgtcaaatca tcatgcccct 1200 tatgacttgg gctacacacg tgctacaatg gcgtaaacaa agtgaagcga agtcgtgagg 1260 ccaagcaaat cacaaaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtc gaaaatgccc gaagtcggtg acctaacgaa 1440 agaaggagcc gccgaaggca ggtttgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 46 <211> 1529 <212> DNA <213> Eubacterium eligens <400> 46 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttagaaca gattatttcg gtatgaagtt ctttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctt gtactggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac aatgttgcat gacatggtgt gaaaaactcc ggtggtataa 240 gatggacccg cgtctgatta gctagttggt gagataacag cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca tgcaagtcag aagtgaaaat 600 ccggggctca accccggaac tgcttttgaa actgtgaggc tggagtgcag gaggggtgag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctcactg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccc ataagggctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatccc actgaccgga cagtaatgtg tcctttcctt 1020 cgggacagtg gagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctatcc ttagtagcca gcagtaagat gggcactcta 1140 gggagactgc cagggataac ctggaggaag gtggggatga cgtcaaatca tcatgcccct 1200 tatgacttgg gctacacacg tgctacaatg gcgtaaacaa agtgaagcaa agtcgtgagg 1260 ccaagcaaat cacaaaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtc gaaaatgccc gaagtcggtg acctaacgca 1440 agaaggagcc gccgaaggca ggtttgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 47 <211> 1529 <212> DNA <213> Eubacterium eligens <400> 47 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttgcgaca gattttttcg gaatgaagtt gcttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctt gtactggggg atagcagctg gaaacggctg 180 gtaataccgc ataagcgcac aatgttgcat gacatggtgt gaaaaactcc ggtggtataa 240 gatggacccg cgtctgatta gctagttggt gagataacag cccaccaagg cgacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcca tgcaagtcag aagtgaaaat 600 ccggggctca accccggaac tgcttttgaa actgtaaggc tggagtgcag gaggggtgag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctcactg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccc ataagggctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatccc actgaccgga cagtaatgtg tcctttcctt 1020 cgggacagtg gagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctatcc ttagtagcca gcagtaagat gggcactcta 1140 gggagactgc cagggataac ctggaggaag gtggggatga cgtcaaatca tcatgcccct 1200 tatgacttgg gctacacacg tgctacaatg gcgtaaacaa agtgaagcga agtcgtgagg 1260 ccaagcaaat cacaaaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtc gaaaatgccc gaagtcggtg acctaacgta 1440 agaaggagcc gccgaaggca ggtttgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 48 <211> 1531 <212> DNA <213> Eubacterium ventriosum <400> 48 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaata catgcaagtc 60 gaacgaagca ccttggacag aatccttcgg gaggaagacc attgtgactg agtggcggac 120 gggtgagtaa cgcgtgggta acctgccttg tacaggggga taacagttgg aaacgactgc 180 taataccgca taagcgcaca gtaccgcatg gtacggtgtg aaaaactccg gtggtacaag 240 atggacccgc gtctgattag ctggttggtg aggtaacggc ccaccaaggc gacgatcagt 300 agccgacttg agagagtgat cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tagggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggaagaagt atttcggtat gtaaacttct atcagcaagg aagaaaatga cggtacttga 480 ctaagaagcc ccggctaaat acgtgccagc agccgcggta atacgtatgg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt aggcggcatg gcaagtcaga agtgaaagcc 600 tggggctcaa ccccggaatt gcttttgaaa ctgtcaggct agagtgtcgg aggggtaagc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccgg tggcgaaggc 720 ggcttactgg acgattactg acgctgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga atactaggtg tcgggggaca atagttcctc 840 ggtgccgaag caaacgcatt aagtattcca cctggggagt acgttcgcaa gaatgaaact 900 caaaggaatt gacggggacc cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg 960 cgaagaacct tacctgctct tgacatccca ctgacaggtc agtaatgtga ccctttcttc 1020 ggaacagtgg agacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt 1080 aagtcccgca acgagcgcaa cccttgtctt tagtagccag cagtacggct gggcactcta 1140 gagagactgc cagggataac ctggaggaag gcggggatga cgtcaaatca tcatgcccct 1200 tacgagcagg gctacacacg tgctacaatg gcgtaaacaa agggaagcga ccccgtgagg 1260 gtaagcaaat ctcaaaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgcgaatcag aatgtcgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtt ggatatgccc gaagtcagtg acccaaccgt 1440 aaggagggag ctgccgaagg tggagccgat aactggggtg aagtcgtaac aaggtagccg 1500 tatcggaagg tgcggctgga tcacctcctt t 1531 <210> 49 <211> 1527 <212> DNA <213> Ruminococcus obeum <400> 49 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa cttttcattg aagcttcggc agatttggtc tgtttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa caaccagaaa tggttgctaa 180 taccgcataa gcgcacagga ccgcatggtc cggtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggcaggg taacggccta ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt gaaaggcggg 600 ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag ctcttcggtg 840 ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccctctga ccgttcctta accggaactt tccttcggga 1020 cagaggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatccccagt agccagcggt tcggccgggc actctgagga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagcct gcgaaggtaa 1260 gcaaatccca aaaataacgt cccagttcgg actgcagtct gcaactcgac tgcacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct aactgcaaag 1440 aaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 50 <211> 1527 <212> DNA <213> Ruminococcus obeum <400> 50 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa cttttcattg aagcttcggc agatttggtc tgtttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa caaccagaaa tggttgctaa 180 taccgcataa gcgcacagga ccgcatggtc tagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggcaggg taacggccta ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt gaaaggcggg 600 ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag ctcttcggtg 840 ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccctctga ccgttcctta accggaactt tccttcggga 1020 caggggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatccccagt agccagcagt ccggctgggc actctgagga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcaagcct gcgaaggtaa 1260 gcaaatccca aaaataacgt cccagttcgg actgcagtct gcaactcgac tgcacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct aactgcaaag 1440 aaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 51 <211> 1100 <212> DNA <213> Ruminococcus obeum <400> 51 gacacggccc agactcctac gggaggcagc agtggggaat attgtacaat gggggaaacc 60 ctgatgcagc gacgccgcgt gaaggaagaa gtatctcggt atgtaaactt ctatcagcag 120 ggaagatagt gacggtacct gactaagaag ccccggctaa ctacgtgcca gcagccgcgg 180 taatacgtag ggggcaagcg ttatccggat ttactgggtg taaagggagc gtagacggac 240 tggcaagtct gatgtgaaag gcgggggctc aacccctgga ctgcattgga aactgttagt 300 cttgagtgcc ggagaggtaa gcggaattcc tagtgtagcg gtgaaatgcg tagatattag 360 gaggaacacc agtggcgaag gcggcttact ggacggtaac tgacgttgag gctcgaaagc 420 gtggggagca aacaggatta gataccctgg tagtccacgc cgtaaacgat gaatactagg 480 tgttggggag caaagctctt cggtgccgcc gcaaacgcat taagtattcc acctggggag 540 tacgttcgca agaatgaaac tcaaaggaat tgacggggac ccgcacaagc ggtggagcat 600 gtggtttaat tcgaagcaac gcgaagaacc ttaccaagtc ttgacatccc tctgaccgac 660 tcttaaccga gtctttcctt cgggacaggg gagacaggtg gtgcatggtt gtcgtcagct 720 cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctatcc ccagtagcca 780 gcagtccggc tgggcactct gaggagactg ccagggataa cctggaggaa ggcggggatg 840 acgtcaaatc atcatgcccc ttatgatttg ggctacacac gtgctacaat ggcgtaaaca 900 aagggaagca agcctgcgaa ggtaagcaaa tccccaaaaa taacgatccc agttcggact 960 gctgtctgca actcgactgc acgaagctgg aattcgctag taatcgcgga tcaaatgccg 1020 cggtgaatac gttcccggga tctgtacaca cccgcccgtc catccttggg agtctgtacc 1080 cccgatttag tggacctacc 1100 <210> 52 <211> 984 <212> DNA <213> Ruminococcus obeum <400> 52 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa cttttcattg aagcttcggc agatttggtc tgtttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa caaccagaaa tggttgctaa 180 taccgcataa gcgcacagga ccgcatggtc cggtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggcaggg taacggccta ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt gaaaggcggg 600 ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag ctcttcggtg 840 ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggatttgacg ggggacccgc acagcggtgg agcatgtggt ttattcgagc acggcgaaga 960 accttaccaa gtctgacatc ccct 984 <210> 53 <211> 939 <212> DNA <213> Ruminococcus obeum <400> 53 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa ccttttattg aagcttcggc agatttagct ggtttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa caaccagaaa tggttgctaa 180 taccgcataa gcgcacagga ccgcatggtc cggtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggcaggg taacggccta ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt gaaaggcggg 600 ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaagcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 ctggtagtcc acgccgtaaa cgatgaatac tagtgttggg ggagcaaagc tcttcgtgcc 840 gccgcaaacg cattagtatt ccacctgggg agtacgttcg caagaatgaa actcaaagga 900 attgaccggc acccacaaac gcgtgagtca gggtgttaa 939 <210> 54 <211> 1529 <212> DNA <213> Ruminococcus torques <400> 54 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtggccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tgggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 55 <211> 1529 <212> DNA <213> Ruminococcus torques <400> 55 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tccccgcaac gagcgcaacc cctatcttta gtagccagcg gccaggccgg gcactctaga 1140 gagactgccg gggataaccc ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgagcagggc tacacacgtg ctacaatggc gtaaacaaag ggaagcgaga ccgcgaggtg 1260 gagcaaatcc caaaaataac gtctcagttc ggattgtagt ctgcaactcg actacatgaa 1320 gctggaatcg ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag taacgcccga agtcagtgac ccaaccgtaa 1440 ggagggagct gccgaaggcg ggaccgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 56 <211> 1056 <212> DNA <213> Ruminococcus torques <400> 56 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta cctgctcttg acatcccgct gaccggacgg taatgcgtcc ttcccttcgg 1020 gcagcggaga caggtggtgc atggttgtcg tcagct 1056 <210> 57 <211> 1529 <212> DNA <213> Ruminococcus torques <400> 57 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtggccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tgggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 58 <211> 1177 <212> DNA <213> Ruminococcus torques <400> 58 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct ggttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct gggggagtac gttcgcaaga atgaaactca 900 aaggaattga cgggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgctctt gacatcccgc tgaccggacg gtaatgcgtc cttcccttcg 1020 gggcagcgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcac gagcgcaacc ctatctttag tagcagcggc caggccgggc actctaaaag 1140 agactgccgg ggataatccc gggaggaagg tggggat 1177 <210> 59 <211> 1528 <212> DNA <213> Ruminococcus torques <400> 59 tacgagagtt tgatcctggc tcaggatgaa cgcgggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtggccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 60 <211> 1529 <212> DNA <213> Dorea_longicatena <400> 60 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg cttaagtttg attcttcgga tgaagacttt tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacggt accgcatggt acagtggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cacaatggag gaaactctga tgcagcgacg ccgcgtgaag 420 gatgaagtat ttcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcacggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gctgagctag agtgtcggag aggcaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttgctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact gctaggtgtc gggtggcaaa gccattcggt 840 gccgcagcta acgcaataag cagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgatcttga catcccgatg accgcttcgt aatggaagtt tttcttcgga 1020 acatcggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatcttcag tagccagcag gttaagctgg gcactctgga 1140 gagactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgaccagggc tacacacgtg ctacaatggc gtaaacaaag agaagcgaac tcgcgagggt 1260 aagcaaatct caaaaataac gtctcagttc ggattgtagt ctgcaactcg actacatgaa 1320 gctggaatcg ctagtaatcg cagatcagaa tgctgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag taacgcccga agtcagtgac ccaaccgtaa 1440 ggagggagct gccgaaggtg ggaccgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 61 <211> 825 <212> DNA <213> Dorea_longicatena <400> 61 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg ctttggaaag attcttcgga tgatttcctt tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacggt accgcatggt acagtggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cacaatggag gaaactctga tgcagcgacg ccgcgtgaag 420 gatgaagtat ttcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcacggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gctgagctag agtgtcggag aggcaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaagcggc 720 ttgctggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtgg 825 <210> 62 <211> 1530 <212> DNA <213> Anaerostipes_caccae <400> 62 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcat ttaggattga agttttcgga tggatttcct atatgactga gtggcggacg 120 ggtgagtaac gcgtggggaa cctgccctat acagggggat aacagctgga aacggctgct 180 aataccgcat aagcgcacag aatcgcatga ttcagtgtga aaagccctgg cagtatagga 240 tggtcccgcg tctgattagc tggttggtga ggtaacggct caccaaggcg acgatcagta 300 gccggcttga gagagtgaac ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag 420 tgaagaagta tttcggtatg taaagctcta tcagcaggga agaaaacaga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggaatt actgggtgta aagggtgcgt aggtggcatg gtaagtcaga agtgaaagcc 600 cggggcttaa ccccgggact gcttttgaaa ctgtcatgct ggagtgcagg agaggtaagc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg actgtcactg acactgatgc acgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga atactaggtg tcggggccgt agaggcttcg 840 gtgccgcagc aaacgcagta agtattccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctggtctt gacatcccaa tgaccgaacc ttaaccggtt ttttctttcg 1020 agacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctatcttt agtagccagc attacggatg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggacgac gtcaaatcat catgcccctt 1200 atggccaggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcgaa gtcgtgaggc 1260 gaagcaaatc ccagaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gtgaatcaga atgtcacggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagtcagtga cccaaccgca 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 63 <211> 857 <212> DNA <213> Anaerostipes_caccae <400> 63 ctagcggtga atgcgtagat attaggagga acaccagtgg cgaaggcggc ttactggact 60 gtcactgaca ctgatgcacg aaagcgtggg gagcaaacag gattagatac cctggtagtc 120 cacgccgtaa acgatgaata ctaggtgtcg gggccgtaga ggcttcggtg ccgcagcaaa 180 cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa ggaattgacg 240 gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc 300 tggtcttgac atcccaatga gcgaacctta accggttttt tctttcgaga cattggagac 360 aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga 420 gcgcaacccc tatctttagt agccagcatt taaggtgggc actctagaga gactgccagg 480 gataacctgg aggaaggtgg ggacgacgtc aaatcatcat gccccttatg gccagggcta 540 cacacgtgct acaatggcgt aaacaaaggg aagcgaagtc gtgaggcgaa gcaaatccca 600 gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc tggaatcgct 660 agtaatcgtg aatcagaatg tcacggtgaa tacgttcccg ggtcttgtac acaccgcccg 720 tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgcaagg agggagctgc 780 cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg 840 gctggatcac ctccttt 857 <210> 64 <211> 1442 <212> DNA <213> Anaerostipes_caccae <220> <221> misc_feature <222> (1442) <223> n is a, c, g, or t <400> 64 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcat ttaggattga agttttcgga tggatttcct atatgactga gtggcggacg 120 ggtgagtaac gcgtggggaa cctgccctat acagggggat aacagctgga aacggctgct 180 aataccgcat aagcgcacag aatcgcatga ttcagtgtga aaagccctgg cagtatagga 240 tggtcccgcg tctgattagc tggttggtga ggtaacggct caccaaggcg acgatcagta 300 gccggcttga gagagtgaac ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag 420 tgaagaagta tttcggtatg taaagctcta tcagcaggga agaaaacaga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggaatt actgggtgta aagggtgcgt aggtggcatg gtaagtcaga agtgaaagcc 600 cggggcttaa ccccgggact gcttttgaaa ctgtcatgct ggagtgcagg agaggtaagc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg actgtcactg acactgatgc acgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga atactaggtg tcggggccgt agaggcttcg 840 gtgccgcagc aaacgcagta agtattccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctggtctt gacatcccaa tgaccgaacc ttaaccggtt ttttctttcg 1020 agacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctatcttt agtagccagc atttaaggtg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggacgac gtcaaatcat catgcccctt 1200 atggccaggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcgaa gtcgtgaggc 1260 gaagcaaatc ccagaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gtgaatcaga atgtcacggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagtcagtga cccaaccgca 1440 an 1442 <210> 65 <211> 1530 <212> DNA <213> Anaerostipes_caccae <400> 65 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcat ttaggattga agttttcgga tggatttcct atatgactga gtggcggacg 120 ggtgagtaac gcgtggggaa cctgccctat acagggggat aacagctgga aacggctgct 180 aataccgcat aagcgcacag aatcgcatga ttcagtgtga aaagccctgg cagtatagga 240 tggtcccgcg tctgattagc tggttggtga ggtaacggct caccaaggcg acgatcagta 300 gccggcttga gagagtgaac ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag 420 tgaagaagta tttcggtatg taaagctcta tcagcaggga agaaaacaga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggaatt actgggtgta aagggtgcgt aggtggcatg gtaagtcaga agtgaaagcc 600 cggggcttaa ccccgggact gcttttgaaa ctgtcatgct ggagtgcagg agaggtaagc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg actgtcactg acactgatgc acgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga atactaggtg tcggggccgt agaggcttcg 840 gtgccgcagc aaacgcagta agtattccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctggtctt gacatcccaa tgaccgaacc ttaaccggtt ttttctttcg 1020 agacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctatcttt agtagccagc atttaaggtg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggacgac gtcaaatcat catgcccctt 1200 atggccaggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcgaa gtcgtgaggc 1260 gaagcaaatc ccagaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gtgaatcaga atgtcacggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagtcagtga cccaaccgca 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 66 <211> 1531 <212> DNA <213> Anaerostipes_caccae <400> 66 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcat ttaggattga agttttcgga tggatttcct atatgactga gtggcggacg 120 ggtgagtaac gcgtggggaa cctgccctat acagggggga taacagctgg aaacggctgc 180 taataccgca taagcgcaca gaatcgcatg attcagtgtg aaaagccctg gcagtatagg 240 atggtcccgc gtctgattag ctggttggtg aggtaacggc tcaccaaggc gacgatcagt 300 agccggcttg agagagtgaa cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 gtgaagaagt atttcggtat gtaaagctct atcagcaggg aagaaaacag acggtacctg 480 actaagaagc cccggctaac tacgtgccag cagccgcggt aatacgtagg gggcaagcgt 540 tatccggaat tactgggtgt aaagggtgcg taggtggcat ggtaagtcag aagtgaaagc 600 ccggggctta accccgggac tgcttttgaa actgtcatgc tggagtgcag gagaggtaag 660 cggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggcttactg gactgtcact gacactgatg cacgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggccg tagaggcttc 840 ggtgccgcag caaacgcagt aagtattcca cctggggagt acgttcgcaa gaatgaaact 900 caaaggaatt gacggggacc cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg 960 cgaagaacct tacctggtct tgacatccca atgagcgaac cttaaccggt tttttctttc 1020 gagacattgg agacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt 1080 aagtcccgca acgagcgcaa cccctatctt tagtagccag catttaaggt gggcactcta 1140 gagagactgc cagggataac ctggaggaag gtggggacga cgtcaaatca tcatgcccct 1200 tatggccagg gctacacacg tgctacaatg gcgtaaacaa agggaagcga agtcgtgagg 1260 cgaagcaaat cccagaaata acgtctcagt tcggattgta gtctgcaact cgactacatg 1320 aagctggaat cgctagtaat cgtgaatcag aatgtcacgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtc agtaacgccc gaagtcagtg acccaaccgc 1440 aaggagggag ctgccgaagg tgggaccgat aactggggtg aagtcgtaac aaggtagccg 1500 tatcggaagg tgcggctgga tcacctcctt t 1531 <210> 67 <211> 1505 <212> DNA <213> Eubacterium siraeum <400> 67 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggtgaag aggagcttgc tcctcggatc agtggcggac gggtgagtaa cacgtgagca 120 acctggctct aagaggggga caacagttgg aaacgactgc taataccgca taacgtatcg 180 ggatggcatc ttcctgatac caaagatttt atcgcttaga gatgggctcg cgtctgatta 240 gatagttggc ggggtaacgg cccaccaagt cgacgatcag tagccggact gagaggttga 300 acggccacat tgggactgag acacggccca gactcctacg ggaggcagca gtgggggata 360 ttggacaatg ggggcaaccc tgatccagcg acgccgcgtg agggaagaag gttttcggat 420 tgtaaacctc tgttgacgga gaaaaaaatg atggtatccg tttagaaagc cacggctaac 480 tacgtgccag cagccgcggt aatacgtagg tggcaagcgt tgtccggaat tactgggtgt 540 aaagggagtg taggcgggat atcaagtcag aagtgaaaat tacgggctca actcgtaacc 600 tgcttttgaa actgacattc ttgagtgaag tagaggcaag cggaattcct agtgtagcgg 660 tgaaatgcgt agatattagg aggaacacca gtggcgaagg cggcttgctg ggcttttact 720 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc 780 gtaaacgatg attactaggt gtggggggat tgaccccttc cgtgccggag taaacacaat 840 aagtaatcca cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc 900 cgcacaagca gtggagtatg tggtttaatt cgacgcaacg cgaagaacct taccaggtct 960 tgacatcgag tgaccgccta agagattagg ctttcccttc ggggacacaa agacaggtgg 1020 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa 1080 cccttatcat tagttgctac gcaagagcac tctaatgaga ctgccgttga caaaacggag 1140 gaaggtgggg atgacgtcaa atcatcatgc cctttatgac ctgggctaca cacgtactac 1200 aatggcgttt aacaaagaga agcaaagccg cgaggcagag caaatctcca aaaaacgtct 1260 cagttcggat tgtaggctgc aactcgccta catgaagtcg gaattgctag taatcgtagg 1320 tcagcatact acggtgaata cgttcccggg ccttgtacac accgcccgtc aaaccatgag 1380 agttggcaac acccgaagtc ggtagtctaa ccgcaaggag gacgccgccg aaggtggggt 1440 tgatgattag ggttaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct 1500 ccttt 1505 <210> 68 <211> 1505 <212> DNA <213> Eubacterium siraeum <400> 68 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggtgaag aggagcttgc tcctcggaac agtggcggac gggtgagtaa cacgtgagca 120 acctggctct aagaggggga caacagttgg aaacgactgc taataccgca taacgtatcg 180 ggatggcatc ttcctgatac caaagatttt atcgcttaga gatgggctcg cgtctgatta 240 gatagttggc ggggtaacgg cccaccaagt cgacgatcag tagccggact gagaggttga 300 acggccacat tgggactgag acacggccca gactcctacg ggaggcagca gtgggggata 360 ttggacaatg ggggcaaccc tgatccagcg acgccgcgtg agggaagaag gttttcggat 420 tgtaaacctc tgttgacgga gaaaaaaatg atggtatccg tttagaaagc cacggctaac 480 tacgtgccag cagccgcggt aatacgtagg tggcaagcgt tgtccggaat tactgggtgt 540 aaagggagtg taggcgggat atcaagtcag aagtgaaaat tacgggctca actcgtaacc 600 tgcttttgaa actgacattc ttgagtgaag tagaggcaag cggaattcct agtgtagcgg 660 tgaaatgcgt agatattagg aggaacacca gtggcgaagg cggcttgctg ggcttttact 720 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc 780 gtaaacgatg attactaggt gtggggggat tgaccccttc cgtgccggag taaacacaat 840 aagtaatcca cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc 900 cgcacaagca gtggagtatg tggtttaatt cgacgcaacg cgaagaacct taccaggtct 960 tgacatcgag tgaccgccta agagattagg ctttcccttc ggggacacaa agacaggtgg 1020 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa 1080 cccttatcat tagttgctac gcaagagcac tctaatgaga ctgccgttga caaaacggag 1140 gaaggtgggg atgacgtcaa atcatcatgc cctttatgac ctgggctaca cacgtactac 1200 aatggcgttt aacaaagaga agcaaagccg cgaggcagag caaatctcca aaaaacgtct 1260 cagttcggat tgtaggctgc aactcgccta catgaagtcg gaattgctag taatcgtagg 1320 tcagcatact acggtgaata cgttcccggg ccttgtacac accgcccgtc aaaccatgag 1380 agttggcaac acccgaagtc ggtagtctaa ccgcaaggag gacgccgccg aaggtggggt 1440 tgatgattag ggttaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct 1500 ccttt 1505 <210> 69 <211> 1505 <212> DNA <213> Eubacterium siraeum <400> 69 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggtgaag aggagcttgc tcctcggatc agtggcggac gggtgagtaa cacgtgagca 120 acctggctct aagaggggga caacagttgg aaacgactgc taataccgca tgatgtatcg 180 ggatggcatc ttcctgatac caaagatttt atcgcttaga gatgggctcg cgtctgatta 240 gatagttggc ggggtaacgg cccaccaagt cgacgatcag tagccggact gagaggttga 300 acggccacat tgggactgag acacggccca gactcctacg ggaggcagca gtgggggata 360 ttggacaatg ggggcaaccc tgatccagcg acgccgcgtg agggaagaag gttttcggat 420 tgtaaacctc tgttgacgga gaaaaaaatg atggtatccg tttagaaagc cacggctaac 480 tacgtgccag cagccgcggt aatacgtagg tggcaagcgt tgtccggaat tactgggtgt 540 aaagggagtg taggcgggat atcaagtcag aagtgaaaat tacgggctca actcgtaacc 600 tgcttttgaa actgacattc ttgagtgaag tagaggcaag cggaattcct agtgtagcgg 660 tgaaatgcgt agatattagg aggaacacca gtggcgaagg cggcttgctg ggcttttact 720 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc 780 gtaaacgatg attactaggt gtggggggat tgaccccttc cgtgccggag taaacacaat 840 aagtaatcca cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc 900 cgcacaagca gtggagtatg tggtttaatt cgacgcaacg cgaagaacct taccaggtct 960 tgacatcgag tgaccgccta agagattagg ctttcccttc ggggacacaa agacaggtgg 1020 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa 1080 cccttatcat tagttgctac gcaagagcac tctaatgaga ctgccgttga caaaacggag 1140 gaaggtgggg atgacgtcaa atcatcatgc cctttatgac ctgggctaca cacgtactac 1200 aatggcgttt aacaaagaga agcaaagccg cgaggcagag caaatctcca aaaaacgtct 1260 cagttcggat tgtaggctgc aactcgccta catgaagtcg gaattgctag taatcgtagg 1320 tcagcatact acggtgaata cgttcccggg ccttgtacac accgcccgtc aaaccatgag 1380 agttggcaac acccgaagtc ggtagtctaa ccgcaaggag gacgccgccg aaggtggggt 1440 tgatgattag ggttaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct 1500 ccttt 1505 <210> 70 <211> 1505 <212> DNA <213> Eubacterium siraeum <400> 70 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggtgaag aggagcttgc tcctcggatc agtggcggac gggtgagtaa cacgtgagca 120 acctggctct aagaggggga caacagttgg aaacgactgc taataccgca taacgtatcg 180 ggatggcatc ttcctgatac caaagatttt atcgcttaga gatgggctcg cgtctgatta 240 gatagttggc ggggtaacgg cccaccaagt cgacgatcag tagccggact gagaggttga 300 acggccacat tgggactgag acacggccca gactcctacg ggaggcagca gtgggggata 360 ttggacaatg ggggcaaccc tgatccagcg acgccgcgtg agggaagaag gttttcggat 420 tgtaaacctc tgttgacgga gaaaaaaatg atggtatccg tttagaaagc cacggctaac 480 tacgtgccag cagccgcggt aatacgtagg tggcaagcgt tgtccggaat tactgggtgt 540 aaagggagtg taggcgggat atcaagtcag aagtgaaaat tacgggctca actcgtaacc 600 tgcttttgaa actgacattc ttgagtgaag tagaggcaag cggaattcct agtgtagcgg 660 tgaaatgcgt agatattagg aggaacacca gtggcgaagg cggcttgctg ggcttttact 720 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc 780 gtaaacgatg attactaggt gtggggggat tgaccccttc cgtgccggag taaacacaat 840 aagtaatcca cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc 900 cgcacaagca gtggagtatg tggtttaatt cgacgcaacg cgaagaacct taccaggtct 960 tgacatcgag tgaccgccta agagattagg ccttcccttc ggggacacaa agacaggtgg 1020 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa 1080 cccttatcat tagttgctac gcaagagcac tctaatgaga ctgccgttga caaaacggag 1140 gaaggtgggg atgacgtcaa atcatcatgc cctttatgac ctgggctaca cacgtactac 1200 aatggcgttt aacaaagaga agcaaagccg cgaggcagag caaatctcca aaaaacgtct 1260 cagttcggat tgtaggctgc aactcgccta catgaagtcg gaattgctag taatcgtagg 1320 tcagcatact acggtgaata cgttcccggg ccttgtacac accgcccgtc aaaccatgag 1380 agttggcaac acccgaagtc ggtagtctaa ccgcaaggag gacgccgccg aaggtggggt 1440 tgatgattag ggttaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct 1500 ccttt 1505 <210> 71 <211> 1548 <212> DNA <213> Clostridium leptum <400> 71 tttagagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaac acatgcaagt 60 cgaacggagt taaattcgac acccgagtat ccggccggga ggcggggtgc tgggggttgg 120 atttaactta gtggcggacg ggtgagtaac gcgtgagtaa cctgcctttc agagggggat 180 aacgttctga aaagaacgct aataccgcat aacatcaatt tatcgcatga taggttgatc 240 aaaggagcaa tccgctggaa gatggactcg cgtccgatta gccagttggc ggggtaacgg 300 cccaccaaag cgacgatcgg tagccggact gagaggttga acggccacat tgggactgag 360 acacggccca gactcctacg ggaggcagca gtgggggata ttgcacaatg ggggaaaccc 420 tgatgcagca acgccgcgtg agggaagaag gttttcggat tgtaaacctc tgttcttagt 480 gacgataatg acggtagcta aggagaaagc tccggctaac tacgtgccag cagccgcggt 540 aatacgtagg gagcgagcgt tgtccggatt tactgggtgt aaagggtgcg taggcggcga 600 ggcaagtcag gcgtgaaatc tatgggctta acccataaac tgcgcttgaa actgtcttgc 660 ttgagtgaag tagaggtagg cggaattccc ggtgtagcgg tgaaatgcgt agagatcggg 720 aggaacacca gtggcgaagg cggcctactg ggctttaact gacgctgaag cacgaaagca 780 tgggtagcaa acaggattag ataccctggt agtccatgcc gtaaacgatg attactaggt 840 gtggggggtc tgaccccctc cgtgccgcag ttaacacaat aagtaatcca cctggggagt 900 acggccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagca gtggagtatg 960 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccgt ctaacgaagc 1020 agagatgcat taggtgccct tcggggaaag gcgagacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttgt ttctagttgc 1140 tacgcaagag cactctagag agactgccgt tgacaaaacg gaggaaggtg gggacgacgt 1200 caaatcatca tgccccttat gacctgggcc acacacgtac tacaatggct gtaaacagag 1260 ggaagcaaag ccgcgaggtg gagcaaaacc ctaaaagcag tcccagttcg gatcgcaggc 1320 tgcaacccgc ctgcgtgaag tcggaattgc tagtaatcgc ggatcagcat gccgcggtga 1380 atacgttccc gggccttgta cacaccgccc gtcacaccat gggagccggt aatacccgaa 1440 gccagtagtt caaccgcaag gagagcgctg tcgaaggtag gattggcgac tggggtgaag 1500 tcgtaacaag gtagccgtat cggaaggtgc ggctggatca cctccttt 1548 <210> 72 <211> 1548 <212> DNA <213> Clostridium leptum <400> 72 tttagagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaac acatgcaagt 60 cgaacggagt taaattcgac acccgagtat ccggccggga ggcggggtgc tgggggttgg 120 atttaactta gtggcggacg ggtgagtaac gcgtgagtaa cctgcctttc agagggggat 180 aacgttctga aaagaacgct aataccgcat aacatcaatt tatcgcatga taggttgatc 240 aaaggagcaa tccgctggaa gatggactcg cgtccgatta gccagttggc ggggtaacgg 300 cccaccaaag cgacgatcgg tagccggact gagaggttga acggccacat tgggactgag 360 acacggccca gactcctacg ggaggcagca gtgggggata ttgcacaatg ggggaaaccc 420 tgatgcagca acgccgcgtg agggaagaag gttttcggat tgtaaacctc tgttcttagt 480 gacgataatg acggtagcta aggagaaagc tccggctaac tacgtgccag cagccgcggt 540 aatacgtagg gagcgagcgt tgtccggatt tactgggtgt aaagggtgcg taggcggcga 600 ggcaagtcag gcgtgaaatc tatgggctta acccataaac tgcgcttgaa actgtcttgc 660 ttgagtgaag tagaggtagg cggaattccc ggtgtagcgg tgaaatgcgt agagatcggg 720 aggaacacca gtggcgaagg cggcctactg ggctttaact gacgctgaag cacgaaagca 780 tgggtagcaa acaggattag ataccctggt agtccatgcc gtaaacgatg attactaggt 840 gtggggggtc tgaccccctc cgtgccgcag ttaacacaat aagtaatcca cctggggagt 900 acggccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagca gtggagtatg 960 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccgt ctaacgaagc 1020 agagatgcat taggtgccct tcggggaaag gcgagacagg tggtgcatgg ttgtcgtcag 1080 ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttgt ttctagttgc 1140 tacgcaagag cactctagag agactgccgt tgacaaaacg gaggaaggtg gggacgacgt 1200 caaatcatca tgccccttat gacctgggcc acacacgtac tacaatggct gtaaacagag 1260 ggaagcaaag ccgcgaggtg gagcaaaacc ctaaaagcag tcccagttcg gatcgcaggc 1320 tgcaacccgc ctgcgtgaag tcggaattgc tagtaatcgc ggatcagcat gccgcggtga 1380 atacgttccc gggccttgta cacaccgccc gtcacaccat gggagccggt aatacccgaa 1440 gccagtagtt caaccgcaag gagagcgctg tcgaaggtag gattggcgac tggggtgaag 1500 tcgtaacaag gtagccgtat cggaaggtgc ggctggatca cctccttt 1548 <210> 73 <211> 1528 <212> DNA <213> Clostridium_bolteae <400> 73 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaagcaa ttgaaggaag ttttcggatg gaattcgatt gactgagtgg cggacgggtg 120 agtaacgcgt ggataacctg cctcacactg ggggataaca gttagaaatg actgctaata 180 ccgcataagc gcacagtacc gcatggtaca gtgtgaaaaa ctccggtggt gtgagatgga 240 tccgcgtctg attagccagt tggcggggta acggcccacc aaagcgacga tcagtagccg 300 acctgagagg gtgaccggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggcgaa agcctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcgaagcaag tctgaagtga aaacccaggg 600 ctcaaccctg ggactgcttt ggaaactgtt ttgctagagt gtcggagagg taagtggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggacgat aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgccgtaaac gatgaatgct aggtgttggg gggcaaagcc cttcggtgcc 840 gtcgcaaacg cagtaagcat tccacctggg gagtacgttc gcaagaatga aactcaaagg 900 aattgacggg gacccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga 960 accttaccaa gtcttgacat cctcttgacc ggcgtgtaac ggcgccttcc cttcggggca 1020 agagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc 1080 cgcaacgagc gcaaccctta tccttagtag ccagcaggta aagctgggca ctctagggag 1140 actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagacag tgatgtggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcga atcagaatgt cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgaccca actcgcaaga 1440 gagggagctg ccgaaggcgg ggcaggtaac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 74 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 74 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agagagagct tgctttcttg agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacggctcgg catcgagcag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctgg ttggtgaggt aacggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acactgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcccttgacg atgctggaaa cagtatttct cttcggagca aggagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 75 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 75 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agaggaggtt tactttctca agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacgacccgg catcgggtag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctag ttggtgaggt aatggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acactgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcctgcgacg cacatagaaa tatgtgtttc cttcgggacg cagagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 76 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 76 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agagagagct tgctttctca agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacgacccgg catcgggtag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctag ttggtgaggt aacggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acaccgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcccttgacg atgctggaaa cagtatttct cttcggagca aggagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 77 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 77 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agagagagct tgctttctca agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacgacccgg catcgggtag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctgg ttggtgaggt aacggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acaccgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcctgcgacg cacatagaaa tatgtgtttc cttcgggacg cagagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 78 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 78 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agagagagct tgctttctca agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacgacccgg catcgggtag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctag ttggtgaggt aacggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattactg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acactgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcctgcgacg cacatagaaa tatgtgtttc cttcgggacg cagagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 79 <211> 1509 <212> DNA <213> Faecalibacterium_prausnitzii <400> 79 tataaagagt ttgatcctgg ctcaggacga acgctggcgg cgcgcctaac acatgcaagt 60 cgaacgagcg agagagagct tgctttctca agcgagtggc gaacgggtga gtaacgcgtg 120 aggaacctgc ctcaaagagg gggacaacag ttggaaacga ctgctaatac cgcataagcc 180 cacgacccgg catcgggtag agggaaaagg agcaatccgc tttgagatgg cctcgcgtcc 240 gattagctag ttggtgaggt aatggcccac caaggcgacg atcggtagcc ggactgagag 300 gttgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtggagga agaaggtctt 420 cggattgtaa actcctgttg ttgaggaaga taatgacggt actcaacaag gaagtgacgg 480 ctaactacgt gccagcagcc gcggtaaaac gtaggtcaca agcgttgtcc ggaattattg 540 ggtgtaaagg gagcgcaggc gggaagacaa gttggaagtg aaatccatgg gctcaaccca 600 tgaactgctt tcaaaactgt ttttcttgag tagtgcagag gtaggcggaa ttcccggtgt 660 agcggtggaa tgcgtagata tcgggaggaa caccagtggc gaaggcggcc tactgggcac 720 caactgacgc tgaggctcga aagtgtgggt agcaaacagg attagatacc ctggtagtcc 780 acactgtaaa cgatgattac taggtgttgg aggattgacc ccttcagtgc cgcagttaac 840 acaataagta atccacctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg 900 gggcccgcac aagcagtgga gtatgtggtt taattcgacg caacgcgaag aaccttacca 960 agtcttgaca tcctgcgacg cacatagaaa tatgtgtttc cttcgggacg cagagacagg 1020 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg 1080 caacccttat ggtcagttac tacgcaagag gactctggcc agactgccgt tgacaaaacg 1140 gaggaaggtg gggatgacgt caaatcatca tgccctttat gacttgggct acacacgtac 1200 tacaatggcg ttaaacaaag agaagcaaga ccgcgaggtg gagcaaaact cagaaacaac 1260 gtcccagttc ggactgcagg ctgcaactcg cctgcacgaa gtcggaattg ctagtaatcg 1320 cagatcagca tgctgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca 1380 tgagagccgg ggggacccga agtcggtagt ctaaccgcaa ggaggacgcc gccgaaggta 1440 aaactggtga ttggggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1500 acctccttt 1509 <210> 80 <211> 1501 <212> DNA <213> Clostridium_bartlettii <400> 80 atttgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaac acatgcaagt 60 cgagcgattc tcttcggaga agagcggcgg acgggtgagt aacgcgtggg taacctgccc 120 tgtacacacg gataacatac cgaaaggtat gctaatacgg gataacataa gaaattcgca 180 tgtttttctt atcaaagctc cggcggtaca ggatggaccc gcgtctgatt agctagttgg 240 tgaggtaacg gctcaccaag gcgacgatca gtagccgacc tgagagggtg atcggccaca 300 ttggaactga gacacggtcc aaactcctac gggaggcagc agtggggaat attgcacaat 360 gggcgaaagc ctgatgcagc aacgccgcgt gagcgatgaa ggccttcggg tcgtaaagct 420 ctgtcctcaa ggaagataat gacggtactt gaggaggaag ccccggctaa ctacgtgcca 480 gcagccgcgg taatacgtag ggggctagcg ttatccggat ttactgggcg taaagggtgc 540 gtaggcggtc ttttaagtca ggagtgaaag gctacggctc aaccgtagta agctcttgaa 600 actggaggac ttgagtgcag gagaggagag tggaattcct agtgtagcgg tgaaatgcgt 660 agatattagg aggaacacca gtagcgaagg cggctctctg gactgtaact gacgctgagg 720 cacgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 780 agtactaggt gtcgggggtt acccccctcg gtgccgcagc taacgcatta agtactccgc 840 ctggggagta cgctcgcaag agtgaaactc aaaggaattg acggggaccc gcacaagtag 900 cggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctaagctt gacatccttt 960 tgaccgatgc ctaatcgcat ctttcccttc ggggacagaa gtgacaggtg gtgcatggtt 1020 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttgcct 1080 ttagttgcca tcattaagtt gggcactcta gagggactgc cagggataac ctggaggaag 1140 gtggggatga cgtcaaatca tcatgcccct tatgcttagg gctacacacg tgctacaatg 1200 ggtggtacag agggcagcga agtcgtgagg ccaagctaat cccttaaagc cattctcagt 1260 tcggattgta ggctgaaact cgcctacatg aagctggagt tactagtaat cgcagatcag 1320 aatgctgcgg tgaatgcgtt cccgggtctt gtacacaccg cccgtcacac catgggagtt 1380 gggggcgccc gaagccggct agctaacctt ttggaagcgg tcgtcgaagg tgaaaccaat 1440 aactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt 1500 t 1501 <210> 81 <211> 1501 <212> DNA <213> Clostridium_bartlettii <400> 81 atttgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaac acatgcaagt 60 cgagcgattc tctttggaga agagcggcgg acgggtgagt aacgcgtggg taacctgccc 120 tgtacacacg gataacatac cgaaaggtat gctaatacgg gataacataa gaaattcgca 180 tgtttttctt atcaaagctc cggcggtaca ggatggaccc gcgtctgatt agctagttgg 240 tgaggtaacg gctcaccaag gcgacgatca gtagccgacc tgagagggtg atcggccaca 300 ttggaactga gacacggtcc aaactcctac gggaggcagc agtggggaat attgcacaat 360 gggcgaaagc ctgatgcagc aacgccgcgt gagcgatgaa ggccttcggg tcgtaaagct 420 ctgtcctcaa ggaagataat gacggtactt gaggaggaag ccccggctaa ctacgtgcca 480 gcagccgcgg taatacgtag ggggctagcg ttatccggat ttactgggcg taaagggtgc 540 gtaggcggtc ttttaagtca ggagtgaaag gctacggctc aaccgtagta agctcttgaa 600 actgggggac ttgagtgcag gagaggagag tggaattcct agtgtagcgg tgaaatgcgt 660 agatattagg aggaacacca gtagcgaagg cggctctctg gactgtaact gacgctgagg 720 cacgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 780 agtactagct gtcggaggtt acccccttcg gtggcgcagc taacgcatta agtactccgc 840 ctggggagta cgctcgcaag agtgaaactc aaaggaattg acggggaccc gcacaagtag 900 cggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctaagctt gacatccttt 960 tgaccgatgc ctaatcgcat ctttcccttc ggggacagaa gtgacaggtg gtgcatggtt 1020 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttgcct 1080 ttagttgcca tcattaagtt gggcactcta gagggactgc cagggataac ctggaggaag 1140 gtggggatga cgtcaaatca tcatgcccct tatgcttagg gctacacacg tgctacaatg 1200 ggtggtacag agggcagcga agtcgtgagg ccaagctaat cccttaaagc cattctcagt 1260 tcggattgta ggctgaaact cgcctacatg aagctggagt tactagtaat cgcagatcag 1320 aatgctgcgg tgaatgcgtt cccgggtctt gtacacaccg cccgtcacac catgggagtt 1380 gggggcgccc gaagccggct agctaacctt ttggaagcgg tcgtcgaagg tgaaaccaat 1440 aactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt 1500 t 1501 <210> 82 <211> 1169 <212> DNA <213> Clostridium_bartlettii <400> 82 gaggcagcag tggggaatat tgcacaatgg gcgaaagcct gatgcagcaa cgccgcgtga 60 gcgatgaagg ccttcgggtc gtaaagctct gtcctcaagg aagataatga cggtacttga 120 ggaggaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggctagcgtt 180 atccggattt actgggcgta aagggtgcgt aggcggtctt ttaagtcagg agtgaaaggc 240 tacggctcaa ccgtagtaag ctcttgaaac tggaggactt gagtgcagga gaggagagtg 300 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt agcgaaggcg 360 gctctctgga ctgtaactga cgctgaggca cgaaagcgtg gggagcaaac aggattagat 420 accctggtag tccacgccgt aaacgatgag tactagctgt cggaggttac ccccttcggt 480 ggcgcagcta acgcattaag tactccgcct ggggagtacg ctcgcaagag tgaaactcaa 540 aggaattgac ggggacccgc acaagtagcg gagcatgtgg tttaattcga agcaacgcga 600 agaaccttac ctaagcttga catccttttg accgatgcct aatcgcatct ttcccttcgg 660 ggacagaagt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 720 agtcccgcaa cgagcgcaac ccttgccttt agttgccatc attaagttgg gcactctaga 780 gggactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 840 tgcttagggc tacacacgtg ctacaatggg tggtacagag ggcagcgaag tcgtgaggcc 900 aagctaatcc cttaaagcca ttctcagttc ggattgtagg ctgaaactcg cctacatgaa 960 gctggagtta ctagtaatcg cagatcagaa tgctgcggtg aatgcgttcc cgggtcttgt 1020 acacaccgcc cgtcacacca tgggagttgg gggcgcccga agccggctag ctaacctttt 1080 ggaagcggtc gtcgaaggtg aaaccaataa ctggggtgaa gtcgtaacaa ggtagccgta 1140 tcggaaggtg cggctggatc acctccttt 1169 <210> 83 <211> 1501 <212> DNA <213> Clostridium_bartlettii <400> 83 atttgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaac acatgcaagt 60 cgagcgatct tcttcggaag agagcggcgg acgggtgagt aacgcgtggg taacctgccc 120 tgtacacacg gataacatac cgaaaggtat gctaatacgg gataacataa gaaattcgca 180 tgtttttctt atcaaagctc cggcggtaca ggatggaccc gcgtctgatt agctagttgg 240 tgaggtaacg gctcaccaag gcgacgatca gtagccgacc tgagagggtg atcggccaca 300 ttggaactga gacacggtcc aaactcctac gggaggcagc agtggggaat attgcacaat 360 gggcgaaagc ctgatgcagc aacgccgcgt gagcgatgaa ggccttcggg tcgtaaagct 420 ctgtcctcaa ggaagataat gacggtactt gaggaggaag ccccggctaa ctacgtgcca 480 gcagccgcgg taatacgtag ggggctagcg ttatccggat ttactgggcg taaagggtgc 540 gtaggcggtc ttttaagtca ggagtgaaag gctacggctc aaccgtagta agctcttgaa 600 actggaggac ttgagtgcag gagaggagag tggaattcct agtgtagcgg tgaaatgcgt 660 agatattagg aggaacacca gtagcgaagg cggctctctg gactgtaact gacgctgagg 720 cacgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 780 agtactagct gtcggaggtt acccccttcg gtggcgcagc taacgcatta agtactccgc 840 ctggggagta cgctcgcaag agtgaaactc aaaggaattg acggggaccc gcacaagtag 900 cggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctaagctt gacatccttt 960 tgaccgatgc ctaatcgcat ctttcccttc ggggacagaa gtgacaggtg gtgcatggtt 1020 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttgcct 1080 ttagttgcca tcattaagtt gggcactcta gagggactgc cagggataac ctggaggaag 1140 gtggggatga cgtcaaatca tcatgcccct tatgcttagg gctacacacg tgctacaatg 1200 ggtggtacag agggcagcga agtcgtgagg ccaagctaat cccttaaagc cattctcagt 1260 tcggattgta ggctgaaact cgcctacatg aagctggagt tactagtaat cgcagatcag 1320 aatgctgcgg tgaatgcgtt cccgggtctt gtacacaccg cccgtcacac catgggagtt 1380 gggggcgccc gaagccggct agctaacctt ttggaagcgg tcgtcgaagg tgaaaccaat 1440 aactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt 1500 t 1501 <210> 84 <211> 905 <212> DNA <213> Clostridium_bartlettii <400> 84 atgcagtcga gcgatcttct tcggagagag cggcggacgg gggagtaacg cgtgggtaac 60 ctgccctgta cacacggatt acataccgaa aggtatgcta atacgggata acataagaaa 120 ttcgcatgtt tttcttatca aagctccggc ggtacaggat ggacccgcgt ctgattagct 180 agttggtgag gtaacggctc accaaggcga cgatcagtag ccgacctgag agggtgatcg 240 gccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg gggaatattg 300 cacaatgggc gaaagcctga tgcagcaacg ccgcgtgagc gatgaaggcc ttcgggtcgt 360 aaagctctgt cctcaaggaa gataatgacg gtacttgagg aggaagcccc ggctaactac 420 gtgccagcag ccgcggtaat acgtaggggg ctagcgttat ccggatttac tgggcgtaaa 480 gggtgcgtag gcggtctttt aagtcaggag tgaaaggcta cggctcaacc gtagtaagct 540 cttgaaactg gaggacttga gtgcaggaga ggagagtgga attcctagtg tagcggtgaa 600 atgcgtagat attaggagga acaccagtag cgaaggcggc tctctggact gtaactgacg 660 ctgaggcacg aaagcgtggg gagcaaacag gattaaatac cctggtattc cacgccgtaa 720 acgatgagta ctagctgtcg gaggttaccc cctttcggtg gcgcagctaa cgcataaata 780 ctcgcctggg gagtacgctc gctagagtga aattaacaga attgactgga tcctgcccaa 840 ttagcggaac atgtgcttga ctcgtaccaa cggaaaaacc ttagcattcc tgcttccttg 900 acgtg 905 <210> 85 <211> 1501 <212> DNA <213> Clostridium_bartlettii <400> 85 atttgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaac acatgcaagt 60 cgagcgattc tcttcggaga agagcggcgg acgggtgagt aacgcgtggg taacctgccc 120 tgtacacacg gataacatac cgaaaggtat gctaatacgg gataacataa gaaattcgca 180 tgtttttctt atcaaagctc cggcggtaca ggatggaccc gcgtctgatt agctagttgg 240 tgaggtaacg gctcaccaag gcgacgatca gtagccgacc tgagagggtg atcggccaca 300 ttggaactga gacacggtcc aaactcctac gggaggcagc agtggggaat attgcacaat 360 gggcgaaagc ctgatgcagc aacgccgcgt gagcgatgaa ggccttcggg tcgtaaagct 420 ctgtcctcaa ggaagataat gacggtactt gaggaggaag ccccggctaa ctacgtgcca 480 gcagccgcgg taatacgtag ggggctagcg ttatccggat ttactgggcg taaagggtgc 540 gtaggcggtc ttttaagtca ggagtgaaag gctacggctc aaccgtagta agctcttgaa 600 actggaggac ttgagtgcag gagaggagag tggaattcct agtgtagcgg tgaaatgcgt 660 agatattagg aggaacacca gtagcgaagg cggctctctg gactgtaact gacgctgagg 720 cacgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 780 agtactagct gtcggaggtt acccccttcg gtggcgcagc taacgcatta agtactccgc 840 ctggggagta cgctcgcaag agtgaaactc aaaggaattg acggggaccc gcacaagtag 900 cggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctaagctt gacatccttt 960 tgaccgatgc ctaatcgcat ctttcccttc ggggacagaa gtgacaggtg gtgcatggtt 1020 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttgcct 1080 ttagttgcca tcattaagtt gggcactcta gagggactgc cagggataac ctggaggaag 1140 gtggggatga cgtcaaatca tcatgcccct tatgcttagg gctacacacg tgctacaatg 1200 ggtggtacag agggcagcga agtcgtgagg ccaagctaat cccttaaagc cattctcagt 1260 tcggattgta ggctgaaact cgcctacatg aagctggagt tactagtaat cgcagatcag 1320 aatgctgcgg tgaatgcgtt cccgggtctt gtacacaccg cccgtcacac catgggagtt 1380 gggggcgccc gaagccggct agctaacctt ttggaagcgg tcgtcgaagg tgaaaccaat 1440 aactggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt 1500 t 1501 <210> 86 <211> 1524 <212> DNA <213> Clostridium ramosum <400> 86 atggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgcgagc acttgtgctc gagtggcgaa cgggtgagta atacataagt aacctgccct 120 agacaggggg ataactattg gaaacgatag ctaagaccgc ataggtacgg acactgcatg 180 gtgaccgtat taaaagtgcc tcaaagcact ggtagaggat ggacttatgg cgcattagct 240 ggttggcggg gtaacggccc accaaggcga cgatgcgtag ccgacctgag agggtgaccg 300 gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta gggaattttc 360 ggcaatgggg gaaaccctga ccgagcaacg ccgcgtgaag gaagaaggtt ttcggattgt 420 aaacttctgt tataaaggaa gaacggcggc tacaggaaat ggtagccgag tgacggtact 480 ttattagaaa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc 540 gttatccgga attattgggc gtaaagaggg agcaggcggc agcaagggtc tgtggtgaaa 600 gcctgaagct taacttcagt aagccataga aaccaggcag ctagagtgca ggagaggatc 660 gtggaattcc atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc agtggcgaag 720 gcgacgatct ggcctgcaac tgacgctcag tcccgaaagc gtggggagca aataggatta 780 gataccctag tagtccacgc cgtaaacgat gagtactaag tgttggatgt caaagttcag 840 tgctgcagtt aacgcaataa gtactccgcc tgagtagtac gttcgcaaga atgaaactca 900 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaggtcttg acatactcat aaaggctcca gagatggaga gatagctata 1020 tgagatacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc 1080 cgcaacgagc gcaaccctta tcgttagtta ccatcattaa gttggggact ctagcgagac 1140 tgccagtgac aagctggagg aaggcgggga tgacgtcaaa tcatcatgcc ccttatgacc 1200 tgggctacac acgtgctaca atggatggtg cagagggaag cgaagccgcg aggtgaagca 1260 aaacccataa aaccattctc agttcggatt gtagtctgca actcgactac atgaagttgg 1320 aatcgctagt aatcgcgaat cagcatgtcg cggtgaatac gttctcgggc cttgtacaca 1380 ccgcccgtca caccacgaga gttgataaca cccgaagccg gtggcctaac cgcaaggaag 1440 gagctgtcta aggtgggatt gatgattggg gtgaagtcgt aacaaggtat ccctacggga 1500 acgtggggat ggatcacctc cttt 1524 <210> 87 <211> 1026 <212> DNA <213> Clostridium scindens <400> 87 cagcagccgc ggtaatacgt agggggcaag cgttatccgg atttactggg tgtaaaggga 60 gcgtagacgg cgatgcaagc cagatgtgaa agcccggggc tcaaccccgg gactgcattt 120 ggaactgcgt ggctggagtg tcggagaggc aggcggaatt cctagtgtag cggtgaaatg 180 cgtagatatt aggaggaaca ccagtggcga aggcggcctg ctggacgatg actgacgttg 240 aggctcgaaa gcgtggggag caaacaggat tagataccct ggtagtccac gccgtaaacg 300 atgactacta ggtgtcgggt ggcaaggcca ttcggtgccg cagcaaacgc aataagtagt 360 ccacctgggg agtacgttcg caagaatgaa actcaaagga attgacgggg acccgcacaa 420 gcggtggagc atgtggttta attcgaagca acgcgaagaa ccttacctga tcttgacatc 480 ccgatgccaa agcgcgtaac gcgctctttc ttcggaacat cggtgacagg tggtgcatgg 540 ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccctat 600 cttcagtagc cagcattttg gatgggcact ctggagagac tgccagggag aacctggagg 660 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc agggctacac acgtgctaca 720 atggcgtaaa caaagggagg cgaacccgcg agggtgggca aatcccaaaa ataacgtctc 780 agttcggatt gtagtctgca actcgactac atgaagctgg aatcgctagt aatcgcgaat 840 cagaatgtcg cggtgaatac gttcccgggt cttgtacaca ccgcccgtca caccatggga 900 gtcagtaacg cccgaagccg gtgacccaac ccgtaaggga gggagccgtc gaaggtggga 960 ccgataactg gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc 1020 tccttt 1026 <210> 88 <211> 1532 <212> DNA <213> Clostridium scindens <400> 88 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagcg cctggccccg acttcttcgg aacgaggagc cttgcgactg agtggcggac 120 gggtgagtaa cgcgtgggca acctgccttg cactggggga taacagccag aaatggctgc 180 taataccgca taagaccgaa gcgccgcatg gcgcggcggc caaagccccg gcggtgcaag 240 atgggcccgc gtctgattag gtagttggcg gggtaacggc ccaccaagcc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaagatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggcgat gcaagccaga tgtgaaagcc 600 cggggctcaa ccccgggact gcatttggaa ctgcgtggct ggagtgtcgg agaggcaggc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcctgctgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga ctactaggtg tcgggtggca aggccattcg 840 gtgccgcagc aaacgcaata agtagtccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgatctt gacatcccga tgccaaagcg cgtaacgcgc tctttcttcg 1020 gaacatcggt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctatcttc agtagccagc attttggatg ggcactctgg 1140 agagactgcc agggagaacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgaccaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa cccgcgaggg 1260 tgggcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agttggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagccggtga cccaacccgt 1440 aagggaggga gccgtcgaag gtgggaccga taactggggt gaagtcgtaa caaggtagcc 1500 gtatcggaag gtgcggctgg atcacctcct tt 1532 <210> 89 <211> 1521 <212> DNA <213> Anaerotruncus_colihominis <400> 89 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggagctt acgttttgaa gttttcggat ggatgaatgt aagcttagtg gcggacgggt 120 gagtaacacg tgagcaacct gcctttcaga gggggataac agccggaaac ggctgctaat 180 accgcatgat gttgcggggg cacatgcccc tgcaaccaaa ggagcaatcc gctgaaagat 240 gggctcgcgt ccgattagcc agttggcggg gtaacggccc accaaagcga cgatcggtag 300 ccggactgag aggttgaacg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg ggggatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagg 420 gaagacggtc ttcggattgt aaacctctgt ctttggggaa gaaaatgacg gtacccaaag 480 aggaagctcc ggctaactac gtgccagcag ccgcggtaat acgtagggag caagcgttgt 540 ccggaattac tgggtgtaaa gggagcgtag gcgggatggc aagtagaatg ttaaatccat 600 cggctcaacc ggtggctgcg ttctaaactg ccgttcttga gtgaagtaga ggcaggcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ctgctgggct ttaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgatta ctaggtgtgg ggggactgac cccttccgtg 840 ccgcagttaa cacaataagt aatccacctg gggagtacgg ccgcaaggtt gaaactcaaa 900 ggaattgacg ggggcccgca caagcagtgg agtatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atcggatgca tagcctagag ataggtgaag cccttcgggg 1020 catccagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attattagtt gctacgcaag agcactctaa tgagactgcc 1140 gttgacaaaa cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg 1200 ctacacacgt actacaatgg cactaaaaca gagggcggcg acaccgcgag gtgaagcgaa 1260 tcccgaaaaa gtgtctcagt tcagattgca ggctgcaacc cgcctgcatg aagtcggaat 1320 tgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg 1380 cccgtcacac catgggagtc ggtaacaccc gaagccagta gcctaaccgc aaggggggcg 1440 ctgtcgaagg tgggattgat gactggggtg aagtcgtaac aaggtagccg tatcggaagg 1500 tgcggctgga tcacctcctt t 1521 <210> 90 <211> 1521 <212> DNA <213> Anaerotruncus_colihominis <400> 90 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggagctt acgttttgaa gttttcggat ggacgaatgt aagcttagtg gcggacgggt 120 gagtaacacg tgagcaacct gcctttcaga gggggataac agccggaaac ggctgctaat 180 accgcatgat gttgcggggg cacatgcccc tgcaaccaaa ggagcaatcc gctgaaagat 240 gggctcgcgt ccgattagcc agttggcggg gtaacggccc accaaagcga cgatcggtag 300 ccggactgag aggttgaacg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg ggggatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagg 420 gaagacggtc ttcggattgt aaacctctgt ctttggggaa gaaaatgacg gtacccaaag 480 aggaagctcc ggctaactac gtgccagcag ccgcggtaat acgtagggag caagcgttgt 540 ccggaattac tgggtgtaaa gggagcgtag gcgggatggc aagtagaatg ttaaatccat 600 cggctcaacc ggtggctgcg ttctaaactg ccgttcttga gtgaagtaga ggcaggcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ctgctgggct ttaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgatta ctaggtgtgg ggggactgac cccttccgtg 840 ccgcagttaa cacaataagt aatccacctg gggagtacgg ccgcaaggtt gaaactcaaa 900 ggaattgacg ggggcccgca caagcagtgg agtatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atcggatgca tagcctagag ataggtgaag cccttcgggg 1020 catccagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attattagtt gctacgcaag agcactctaa tgagactgcc 1140 gttgacaaaa cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg 1200 ctacacacgt actacaatgg cactaaaaca gagggcggcg acaccgcgag gtgaagcgaa 1260 tcccgaaaaa gtgtctcagt tcagattgca ggctgcaacc cgcctgcatg aagtcggaat 1320 tgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg 1380 cccgtcacac catgggagtc ggtaacaccc gaagccagta gcctaaccgc aaggggggcg 1440 ctgtcgaagg tgggattgat gactggggtg aagtcgtaac aaggtagccg tatcggaagg 1500 tgcggctgga tcacctcctt t 1521 <210> 91 <211> 1023 <212> DNA <213> Anaerotruncus_colihominis <400> 91 tcaaagagtt tgatcctggc tcaggacgaa cgctggcggc gcgcctaaca catgcaagtc 60 gaacggagct tacgttttga agttttcgga tggatgaatg taagcttagt ggcggacggg 120 tgagtaacac gtgagcaacc tgcctttcag agggggataa cagccggaaa cggctgctaa 180 taccgcatga tgttgcgggg gcacatgccc ctgcaaccaa aggagcaatc cgctgaaaga 240 tgggctcgcg tccgattagc cagttggcgg ggtaacggcc caccaaagcg acgatcggta 300 gccggactga gaggttgaac ggccacattg ggactgagac acggcccaga ctcctacggg 360 aggcagcagt gggggatatt gcacaatggg cgaaagcctg atgcagcgac gccgcgtgag 420 ggaagacggt cttcggattg taaacctctg tctttgggga agaaaatgac ggtacccaaa 480 gaggaagctc cggctaacta cgtgccagca gccgcggtaa tacgtaggga gcaagcgttg 540 tccggaatta ctgggtgtaa agggagcgta ggcgggatgg caagtagaat gttaaatcca 600 tcggctcaac cggtggctgc gttctaaact gccgttcttg agtgaagtag aggcaggcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cctgctgggc tttaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta acgatgatta ctaggtgtgg ggggactgac cccttccgtg 840 ccgcagttaa cacataagta atccacctgg ggagtacggc cgcaggtgaa ctcaaggatt 900 gacggggccc gcacagcagt gagtatgtgg tttatcgagc acgcgagact acagtctgac 960 atcgatgcat agctagagat agtgagccct cgggcatcca gacaggtggg tgcatgggtg 1020 tcg 1023 <210> 92 <211> 1521 <212> DNA <213> Anaerotruncus_colihominis <400> 92 caaagagttt gatcctggct caggacgaac gctggcggcg cgcctaacac atgcaagtcg 60 aacggagctt acgttttgaa gttttcggat ggatgaatgt aagcttagtg gcggacgggt 120 gagtaacacg tgagcaacct gcctttcaga gggggataac agccggaaac ggctgctaat 180 accgcatgat gttgcggggg cacatgcccc tgcaaccaaa ggagcaatcc gctgaaagat 240 gggctcgcgt ccgattagcc agttggcggg gtaacggccc accaaagcga cgatcggtag 300 ccggactgag aggttgaacg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg ggggatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagg 420 gaagacggtc ttcggattgt aaacctctgt ctttggggaa gaaaatgacg gtacccaaag 480 aggaagctcc ggctaactac gtgccagcag ccgcggtaat acgtagggag caagcgttgt 540 ccggaattac tgggtgtaaa gggagcgtag gcgggatggc aagtagaatg ttaaatccat 600 cggctcaacc ggtggctgcg ttctaaactg ccgttcttga gtgaagtaga ggcaggcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ctgctgggct ttaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgatta ctaggtgtgg ggggactgac cccttccgtg 840 ccgcagttaa cacaataagt aatccacctg gggagtacgg ccgcaaggtt gaaactcaaa 900 ggaattgacg ggggcccgca caagcagtgg agtatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atcggatgca tagcctagag ataggtgaag cccttcgggg 1020 catccagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attattagtt gctacgcaag agcactctaa tgagactgcc 1140 gttgacaaaa cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg 1200 ctacacacgt actacaatgg cactaaaaca gagggcggcg acaccgcgag gtgaagcgaa 1260 tcccgaaaaa gtgtctcagt tcagattgca ggctgcaacc cgcctgcatg aagtcggaat 1320 tgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg 1380 cccgtcacac catgggagtc ggtaacaccc gaagccagta gcctaaccgc aaggggggcg 1440 ctgtcgaagg tgggattgat gactggggtg aagtcgtaac aaggtagccg tatcggaagg 1500 tgcggctgga tcacctcctt t 1521 <210> 93 <211> 1304 <212> DNA <213> Clostridium spiroforme <400> 93 atggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgcgagc agcaatgctc gagtggcgaa cgggtgagta atacataagt aacctgccct 120 agacaggggg ataactgctg gaaacggcag ctaagaccgc ataggtatgg acactgcatg 180 gtgaccatat taaaagtgcc aaggcactgg tagaggatgg acttatggcg cattagctgg 240 ttggtgaggt aacagctcac caaggcgacg atgcgtagcc gacctgagag ggtgaccggc 300 cacactggga ctgagacacg gcccagactc ctacgggagg cagcagtagg gaattttcgg 360 caatgggggg aaccctgacc gagcaacgcc gcgtgaagga agaaggaatt cgttctgtaa 420 acttctgtta taaaggaaga acggcggata tagggaatga tatccgagtg acggtacttt 480 atgagaaagc cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcgagcgt 540 tatccggaat tattgggcgt aaagagggag caggcggcgg cagaggtctg tggtgaaaga 600 ctgaagctta acttcagtaa gccatagaaa ccgggctgct agagtgcagg agaggatcgt 660 ggaattccat gtgtagcggt gaaatgcgta gatatatgga ggaacaccag tggcgaaggc 720 gacggtctgg cctgtaactg acgctcattc ccgaaagcgt ggggagcaaa taggattaga 780 taccctagta gtccacgccg taaacgatga gtactaagtg ttgggagtca aatttcagtg 840 ctgcagttaa cgcaataagt actccgcctg agtagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atccggataa agacctcaga gatgagggga tagatatatc 1020 cgagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg 1080 caacgagcgc aacccttgtc gctagttacc atcattaagt tggggactct agcgagactg 1140 ccagtgacaa gctggaggaa ggcggggatg acgtcaaatc atcatgcccc ttatgacctg 1200 gctacacacg tgctacaatg atggagcaga gggaagcgaa gccgcgagtg agcaaaccca 1260 taaaccattc tcagtcggat tgtagtctgc actcgactac atga 1304 <210> 94 <211> 886 <212> DNA <213> Clostridium spiroforme <400> 94 atggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgcgagc agcaatgctc gagtggcgaa cgggtgagta atacataagt aacctgccct 120 agacaggggg ataactgctg gaaacggcag ctaagaccgc ataggtatgg acactgcatg 180 gtgaccatat taaaagtgcc aaggcactgg tagaggatgg acttatggcg cattagctgg 240 ttggtgaggt aacggctcac caaggcgacg atgcgtagcc gacctgagag ggtgaccggc 300 cacactggga ctgagacacg gcccagactc ctacgggagg cagcagtagg gaattttcgg 360 caatgggggg aaccctgacc gagcaacgcc gcgtgaagga agaaggaatt cgttctgtaa 420 acttctgtta taaaggaaga acggcggata tagggaatga tatccgagtg acggtacttt 480 atgagaaagc cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcgagcgt 540 tatccggaat tattgggcgt aaagagggag caggcggcgg cagaggtcta tggtgaaaga 600 ctgaagctta acttcagtaa gccatagaaa ccgggctgct agagtgcagg agaggatcgt 660 gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccagt ggcgaaggcg 720 acggtctgcc tgtaactgac gctcattccc gaaagcgtgg ggagcaaata ggattagata 780 ccctagtagt ccacgccgta acgatgagta ctaagtgtgg gagtcaaatt tcagtgctgc 840 agttaacgca ataagtacct ccgccttgaa tagtacgttc gcaaga 886 <210> 95 <211> 1390 <212> DNA <213> Clostridium spiroforme <400> 95 atggagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgcgagc agcaatgctc gagtggcgaa cgggtgagta atacataagt aacccgccct 120 agacaggggg ataactgctg gaaacggcag ctaagaccgc ataggtatgg acactgcatg 180 gtgaccatat taaaagtgcc aaggcactgg tagaggatgg acttatggcg cattagctgg 240 ttggtgaggt aacggctcac caaggcgacg atgcgtagcc gacctgagag ggtgaccggc 300 cacactggga ctgagacacg gcccagactc ctacgggagg cagcagtagg gaattttcgg 360 caatgggggg aaccctgacc gagcaacgcc gcgtgaagga agaaggaatt cgttctgtaa 420 acttctgtta taaaggaaga acggcggata tagggaatga tatccgagtg acggtacttt 480 atgagaaagc cacggctaac tacgtgccag cagccgcggt aatacgtagg tggcgagcgt 540 tatccggaat tattgggcgt aaagagggag caggcggcgg cagaggtcta tggtgaaaga 600 ctgaagctta acttcagtaa gccatagaaa ccgggctgct agagtgcagg agaggatcgt 660 ggaattccat gtgtagcggt gaaatgcgta gatatatgga ggaacaccag tggcgaaggc 720 gacggtctgg cctgtaactg acgctcattc ccgaaagcgt ggggagcaaa taggattaga 780 taccctagta gtccacgccg taaacgatga gtactaagtg ttgggagtca aatttcagtg 840 ctgcagttaa cgcaataagt actccgcctg agtagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atccggataa agacctcaga gatgagggga tagatatatc 1020 cgagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg 1080 caacgagcgc aacccttgtc gctagttacc atcattaagt tggggactct agcgagactg 1140 ccagtgacaa gctggaggaa ggcggggatg acgtcaaatc atcatgcccc ttatgacctg 1200 cgctacacac gtgctacaat gtatggagca gagggaagcg aagccgcgag gtgaagcaaa 1260 cccataaacc attctcagtt cggattgtag tctgcaactc gactacatga gtgtatcgct 1320 agtatcgcga tcagcatgtc gcgtgaatac gttctcggcc ttgtacacac cccgcccgtc 1380 aacaccattg 1390 <210> 96 <211> 1517 <212> DNA <213> Anaerofustis_stercorihominis <400> 96 ttttgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgagaa acttataaat gatccttcgg gtgaatctat aagcggacag tggcgaacgg 120 gtgagtaacg cgtaggtaac caacctcatg cagggggata gcccagggaa acttggatta 180 aacccgcata agaccacagc accgcatggt gcaggggtaa aaactccggt ggcatgagac 240 ggacctgcgt cttattaggt agttggtgag gtaacggctc accaagccaa cgatgagtag 300 ccgacctgag agggtgatcg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cgcaatgggg gaaaccctga cgcagcaacg ccgcgtgagc 420 gatgaaggtt ttcggatcgt aaagctctgt ctttggggaa gataatgacg gtacccaagg 480 aggaagctcc ggctaactac gtgccagcag ccgcggtaat acgtagggag caagcgttgt 540 ccggattcac tgggcgtaaa gagcacgtag gcggttaatt aagtcaggtg tgaaagtttt 600 cggctcaacc ggaaaagtgc acttgaaact ggataacttg agtatcggag aggtaagcgg 660 aattcctagt gtagcggtga aatgcgtaga gattaggaag aacaccggtg gcgaaggcgg 720 cttactggac gataactgac gctgaggtgc gaaagcgtgg ggagcgaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtt ggggtaactc agtgccgcag 840 ttaacacatt aagtattccg cctggggagt acgctcgcaa gagtgaaact caaaggaatt 900 gacgggggcc cgcacaagca gcggagcatg tggtttaatt cgaagcaacg cgaagaacct 960 taccaggtct tgacatccct tgaccgccta agagattagg ctttccttcg ggacaaggag 1020 acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac 1080 gagcgcaacc cttatgttta gttactaaca ttcagttgag gactctagac agactgccct 1140 tgaaagaggg aggaaggtgg ggacgacgtc aaatcatcat gccccttacg acctgggcta 1200 cacacgtgct acaatggtct gtacagaggg ttgcgaagca gtgatgctaa gctaatctca 1260 aaaagcagat ctcagttcgg attgcaggct gcaactcgcc tgcatgaagt cggagttgct 1320 agtaatcgcg aatcagaatg tcgcggtgaa tgcgttcccg ggccttgtac acaccgcccg 1380 tcacaccacg agagttggta acacccgaag ccagtgagct aaccattagg aggcagctgt 1440 cgaaggtggg atcagtaatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg 1500 gctggatcac ctccttt 1517 <210> 97 <211> 1517 <212> DNA <213> Anaerofustis_stercorihominis <400> 97 ttttgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgagaa acttataaat gatccttcgg gtgaatctat aagcggacag tggcgaacgg 120 gtgagtaacg cgtaggtaac caacctcatg cagggggata gcccagggaa acttggatta 180 aacccgcata agaccacagc accgcatggt gcaggggtaa aaactccggt ggcatgagac 240 ggacctgcgt cttattaggt agttggtgag gtaacggctc accaagccaa cgatgagtag 300 ccgacctgag agggtgatcg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cgcaatgggg gaaaccctga cgcagcaacg ccgcgtgagc 420 gatgaaggtt ttcggatcgt aaagctctgt ctttggggaa gataatgacg gtacccaagg 480 aggaagctcc ggctaactac gtgccagcag ccgcggtaat acgtagggag caagcgttgt 540 ccggattcac tgggcgtaaa gagcacgtag gcggttaatt aagtcaggtg tgaaagtttt 600 cggctcaacc ggaaaagtgc acttgaaact ggataacttg agtatcggag aggtaagcgg 660 aattcctagt gtagcggtga aatgcgtaga gattaggaag aacaccggtg gcgaaggcgg 720 cttactggac gataactgac gctgaggtgc gaaagcgtgg ggagcgaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtt ggggtaactc agtgccgcag 840 ttaacacatt aagtattccg cctggggagt acgctcgcaa gagtgaaact caaaggaatt 900 gacgggggcc cgcacaagca gcggagcatg tggtttaatt cgaagcaacg cgaagaacct 960 taccaggtct tgacatccct tgaccgccta agagattagg ctttccttcg ggacaaggag 1020 acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac 1080 gagcgcaacc cttatgttta gttactaaca ttcagttgag gactctagac agactgccct 1140 tgaaagaggg aggaaggtgg ggacgacgtc aaatcatcat gccccttacg acctgggcta 1200 cacacgtgct acaatggtct gtacagaggg ttgcgaagca gtgatgctaa gctaatctca 1260 aaaagcagat ctcagttcgg attgcaggct gcaactcgcc tgcatgaagt cggagttgct 1320 agtaatcgcg aatcagaatg tcgcggtgaa tgcgttcccg ggccttgtac acaccgcccg 1380 tcacaccacg agagttggta acacccgaag ccagtgagct aaccattagg aggcagctgt 1440 cgaaggtggg atcagtaatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg 1500 gctggatcac ctccttt 1517 <210> 98 <211> 1527 <212> DNA <213> Clostridiales_bacterium_1_7_47FAA <400> 98 tttgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagca tcttatagga agttttcgga tggaatatgg gatgactgag tggcggacgg 120 gtgagtaacg cgtggataac ctgcctcaca ctgggggata acagttagaa atggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaacccaggt ggtgtgagat 240 ggatccgcgt ctgattagcc agttggcggg gtaacggccc accaaagcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagt 420 gaagaagtat ctcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcgatgc aagtctgaag tgaaagcccg 600 gggctcaacc ccgggactgc tttggaaact gtgtggctgg agtgcaggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac tgtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat gctaggtgtc ggggggcaaa gcccctcggt 840 gccgccgcta acgcaataag cattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catccccctg accggacagt aacgtgtccc ttccttcggg 1020 acaggggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatccttag tagccagcat ttcgggtggg cactctaggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gatttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaccct gcgaaggtga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagca acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggcggg gcaggtaact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 99 <211> 1528 <212> DNA <213> Coprococcus_comes <400> 99 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagca ctttaacctg attcttcgga tgaaggtttt tgtgactgag tggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacaga gccgcatggc tcggtgggaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccaa cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggctgtgt aagtctgaag tgaaagcccg 600 gggctcaacc ccgggactgc tttggaaact atgcagctag agtgtcggag aggtaagtgg 660 aattcccagt gtagcggtga aatgcgtaga tattgggagg aacaccagtg gcgaaggcgg 720 cttactggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc ggggagcaaa gctcttcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccggtg accggcgtgt aatgacgcct tttcttcgga 1020 acaccggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatcttcag tagccagcaa ttcggatggg cactctggag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc tgcgagggta 1260 agcaaatctc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagcat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 100 <211> 1076 <212> DNA <213> Roseburia_intestinalis <400> 100 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttatttgat ttcttcggaa tgaagatttt gtgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttggaaa cgactgctaa 180 taccgcataa gcgcacaggg tcgcatgacc tggtgtgaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattagcca gttggtgggg taacggccta ccaaagcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagcg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aagaaatgac ggtacctgac 480 taagaagcac cggctaaata cgtgccagca gccgcggtaa tacgtatggt gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgca ggcggtacgg caagtctgat gtgaaagccc 600 ggggctcaac cccggtactg cattggaaac tgtcggacta gagtgtcgga ggggtaagtg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cgattactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt cggggagtat tgctcttcgg 840 tgccgcagca aacgcaataa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatcccggt gacagaacat gtaatgtgtt ttctcttcgg 1020 agcatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttggg 1076 <210> 101 <211> 1530 <212> DNA <213> Blautia_hydrogenotrophica <400> 101 cagagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcga tagagaacgg agatttcggt tgaagttttc tattgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccctat acagggggat aacagttaga aatgactgct 180 aataccgcat aagcgcacag cttcgcatga agcggtgtga aaaactgagg tggtatagga 240 tggacccgcg ttggattagc tagttggtga ggtaacggcc caccaaggcg acgatccata 300 gccggcctga gagggtgaac ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgaa 420 ggaagaagta tctcggtatg taaacttcta tcagcaggga agaaagtgac ggtacctgac 480 taagaagccc cggctaatta cgtgccagca gccgcggtaa tacgtaaggg gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgta gacggtttgg caagtctgat gtgaaaggca 600 tgggctcaac ctgtggactg cattggaaac tgtcagactt gagtgccgga gaggcaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcctgctgga cggtaactga cgttgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgctgt aaacgatgaa tactaggtgt cgggtggcaa agccattcgg 840 tgccgcagca aacgcaataa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaaatcttg acatccctct gaccgggaag taatgttccc ttttcttcgg 1020 aacagaggag acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cttattctta gtagccagca ggtagagctg ggcactctag 1140 ggagactgcc agggataacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgatttggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcgaa ggggtgacct 1260 ggagcaaatc tcaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagtcagtga cccaaccgaa 1440 aggagggagc tgccgaaggt gggactgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 102 <211> 1264 <212> DNA <213> Holdemania_filiformis <400> 102 acctaggcga tgatacgtag ccgacctgag agggtgaccg gccacattgg gactgagaca 60 cggcccaaac tcctacggga ggcagcagta gggaattttc ggcaatgggc gaaagcctga 120 ccgagcaacg ccgcgtgagt gaagaaggcc ttcgggttgt aaagctctgt tgtgaaggaa 180 gaacggctca tacagggaat ggtatgggag tgacggtact ttaccagaaa gccacggcta 240 actacgtgcc agcagccgcg gtaatacgta ggtggcgagc gttatccgga attattgggc 300 gtaaagggtg cgcaggcggt ttgttaagtt taaggtgaaa gcgtggggct taaccccata 360 tagccttaga aactgacaga ctagagtaca ggagagggca atggaattcc atgtgtagcg 420 gtaaaatgcg tagatatatg gaggaacacc agtggcgaag gcggttgcct ggcctgtaac 480 tgacgctcat gcacgaaagc gtggggagca aataggatta gataccctag tagtccacgc 540 cgtaaacgat gagaactaag tgttggggaa actcagtgct gcagttaacg caataagttc 600 tccgcctggg gagtatgcac gcaagtgtga aactcaaagg aattgacggg ggcccgcaca 660 agcggtggag tatgtggttt aattcgacgc aacgcgaaga accttaccag gtcttgacat 720 cccctgcaaa gacatagaga tatgttggag gttatcaggg agacaggtgg tgcatggttg 780 tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccttgtctt 840 tagttgctaa cattaagttg aggactctag agagactgcc ggtgacaaac cggaggaagg 900 tggggatgac gtcaaatcat catgcccctt atgacctggg ctacacacgt actacaatgg 960 cggatacaac gagaagcaag acagtgatgt ggagcaaaac tcagaaagtc cgtctcagtt 1020 cggattgaag tctgcaaccc gacttcatga agccggaatc gctagtaatc gcggatcagc 1080 atgccgcggt gaatacgttc tcgggccttg tacacaccgc ccgtcaaacc atgagagttg 1140 gcaatacccg aagccggtgg cctaacctcg caagaggagg gagccgtcga aggtagggct 1200 gatgattggg gttaagtcgt aacaaggtat ccctacggga acgtggggat ggatcacctc 1260 cttt 1264 <210> 103 <211> 1527 <212> DNA <213> Clostridium_asparagiforme <400> 103 tttgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagca ttttagatga agttttcgga tggattctga gatgactgag tggcggacgg 120 gtgagtaaca cgtggataac ctgcctcaca ctgggggaca acagttagaa atgactgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtgtgagat 240 ggatccgcgt ctgattagcc agttggcggg gtaacggccc accaaagcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagt 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gataatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagtctgaag tgaaaaccca 600 gggctcaacc ctgggactgc tttggaaact gtcaagctag agtgcaggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac tgtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt ggggggcaaa gcccttcggt 840 gccgtcgcaa acgcaataag cactccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catccccctg accggcgtgt aacggcgcct ttccttcggg 1020 acaggggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatccttag tagccagcat taagatgggc actctaggga 1140 gactgccagg gacaacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgaccct gcgaaggtga 1260 gcaaatctca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg aatcagaatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagca acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggcggg gcaggtaact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 104 <211> 1528 <212> DNA <213> Blautia_wexlerae <400> 104 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaat tactttattg aaacttcggt cgatttaatt taattctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa cagtcagaaa tggctgctaa 180 taccgcataa gcgcacagag ctgcatggct cagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggtgggg taacggccca ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtgtggca agtctgatgt gaaaggcatg 600 ggctcaacct gtggactgca ttggaaactg tcatacttga gtgccggagg ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg ggtggcagag ccattcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccgcctga ctgatcctta accggatctt tccttcggga 1020 caggcgagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcctcagt agccagcatt taaggtgggc actctgggga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagatt gtgagatgga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg gggagtcagt aacgcccgaa gtcagtgacc taaccgaaag 1440 ggaggagctg ccgaaggcgg gaccgatgac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 105 <211> 1526 <212> DNA <213> Blautia_wexlerae <400> 105 cagagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgggaatt actttattga aacttcggtc gatttaattt aattctagtg gcggacgggt 120 gagtaacgcg tgggtaacct gccttataca gggggataac agtcagaaat ggctgctaat 180 accgcataag cgcacagagc tgcatggctc agtgtgaaaa actccggtgg tataagatgg 240 acccgcgttg gattagctag ttggtggggt aacggcccac caaggcgacg atccatagcc 300 ggcctgagag ggtgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg 360 cagcagtggg gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtgaagga 420 agaagtatct cggtatgtaa acttctatca gcagggaaga tagtgacggt acctgactaa 480 gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc 540 ggatttactg ggtgtaaagg gagcgtagac ggtgtggcaa gtctgatgtg aaaggcatgg 600 gctcaacctg tggactgcat tggaaactgt catacttgag tgccggaggg gtaagcggaa 660 ttcctagtgt agcggtgaaa tgcgtagata ttaggaggaa caccagtggc gaaggcggct 720 tactggacgg taactgacgt tgaggctcga aagcgtgggg agcaaacagg attagatacc 780 ctggtagtcc acgccgtaaa cgatgaatac taggtgtcgg ggagcatggc tcttcggtgc 840 cgtcgcaaac gcagtaagta ttccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccgcctgac cgatccttaa ccggatcttt ccttcgggac 1020 aggcgagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaacccct atcctcagta gccagcattt aaggtgggca ctctggggag 1140 actgccaggg ataacctgga ggaaggcggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcgagattg tgagatggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcgg atcagaatgc cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagtaa cgcccgaagt cagtgaccta actgcaaaga 1440 aggagctgcc gaaggcggga ccgatgactg gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 106 <211> 1526 <212> DNA <213> Blautia_wexlerae <400> 106 cagagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgggaatt actttattga aacttcggtc gatttaattt aattctagtg gcggacgggt 120 gagtaacgcg tgggtaacct gccttataca gggggataac agtcagaaat ggctgctaat 180 accgcataag cgcacagagc tgcatggctc agtgtgaaaa actccggtgg tataagatgg 240 acccgcgttg gattagctgg ttggtggggt aacggcccac caaggcgacg atccatagcc 300 ggcctgagag ggtgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg 360 cagcagtggg gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtgaagga 420 agaagtatct cggtatgtaa acttctatca gcagggaaga tagtgacggt acctgactaa 480 gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc 540 ggatttactg ggtgtaaagg gagcgtagac ggtgtggcaa gtctgatgtg aaaggcatgg 600 gctcaacctg tggactgcat tggaaactgt catacttgag tgccggaggg gtaagcggaa 660 ttcctagtgt agcggtgaaa tgcgtagata ttaggaggaa caccagtggc gaaggcggct 720 tactggacgg taactgacgt tgaggctcga aagcgtgggg agcaaacagg attagatacc 780 ctggtagtcc acgccgtaaa cgatgaatac taggtgtcgg gtagcatagc tcttcggtgc 840 cgtcgcaaac gcagtaagta ttccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccctctgac cgaaacttaa tcggatcttt ccttcgggac 1020 agacgagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaacccct atcctcagta gccagcattt aaggtgggca ctctggggag 1140 actgccaggg ataacctgga ggaaggcggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcgagattg tgagatggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcgg atcagaatgc cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagtaa cgcccgaagt cagtgaccta actgcaaaga 1440 aggagctgcc gaaggcggga ccgatgactg gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 107 <211> 1325 <212> DNA <213> Blautia_wexlerae <400> 107 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa tatttcattg agacttcggt ggatttgatc tatttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa cagtcagaaa tggctgctaa 180 taccgcataa gcgcacagag ctgcatggct cagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagctg gttggtgggg taacggccca ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtgtggca agtctgatgt gaaaggcatg 600 ggctcaacct gtggactgca ttggaaactg tcatacttga gtgccggagg ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg gggagcatgg ctcttcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccgcctga ccgatcctta accggatctt tccttcggga 1020 caggcgagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcctcagt agccagcatt taaggtgggc actctgggga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagatt gtgagatgga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaa 1325 <210> 108 <211> 1526 <212> DNA <213> Blautia_wexlerae <400> 108 cagagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgggaatt actttattga aacttcggtc gatttaattt aattctagtg gcggacgggt 120 gagtaacgcg tgggtaacct gccttataca gggggataac agtcagaaat ggctgctaat 180 accgcataag cgcacagagc tgcatggctc agtgtgaaaa actccggtgg tataagatgg 240 acccgcgttg gattagctag ttggtggggt aacggcccac caaggcgacg atccatagcc 300 ggcctgagag ggtgaacggc cacattggga ctgagacacg gcccagactc ctacgggagg 360 cagcagtggg gaatattgca caatggggga aaccctgatg cagcgacgcc gcgtgaagga 420 agaagtatct cggtatgtaa acttctatca gcagggaaga tagtgacggt acctgactaa 480 gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca agcgttatcc 540 ggatttactg ggtgtaaagg gagcgtagac ggtgtggcaa gtctgatgtg aaaggcatgg 600 gctcaacctg tggactgcat tggaaactgt catacttgag tgccggaggg gtaagcggaa 660 ttcctagtgt agcggtgaaa tgcgtagata ttaggaggaa caccagtggc gaaggcggct 720 tactggacgg taactgacgt tgaggctcga aagcgtgggg agcaaacagg attagatacc 780 ctggtagtcc acgccgtaaa cgatgaatac taggtgtcgg ggagcatggc tcttcggtgc 840 cgtcgcaaac gcagtaagta ttccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccgcctgac cgatccttaa ccggatcttt ccttcgggac 1020 aggcgagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaacccct atcctcagta gccagcattt aaggtgggca ctctggggag 1140 actgccaggg ataacctgga ggaaggcggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcgagattg tgagatggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcgg atcagaatgc cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagtaa cgcccgaagt cagtgaccta actgcaaaga 1440 aggagctgcc gaaggcggga ccgatgactg gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 109 <211> 1527 <212> DNA <213> Blautia_wexlerae <400> 109 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaat tactttattg aaacttcggt cgatttaatt taattctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa cagtcagaaa tggctgctaa 180 taccgcataa gcgcacagag ctgcatggct cagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagctt gttggtgagg taacggccca ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtgtggca agtctgatgt gaaaggcatg 600 ggctcaacct gtggactgca ttggaaactg tcatacttga gtgccggagg ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg gggagcatgg ctcttcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccctctga ccggaactta atcgttcctt tccttcggga 1020 cagaggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcctcagt agccagcatt taaggtgggc actctgggga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagatt gtgagatgga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct aactgcaaag 1440 aaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 110 <211> 1527 <212> DNA <213> Blautia_wexlerae <400> 110 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa tatttcattg agacttcggt ggatttgatc tatttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa cagtcagaaa tggctgctaa 180 taccgcataa gcgcacagag ctgcatggct cagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagctg gttggtgggg taacggccca ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtgtggca agtctgatgt gaaaggcatg 600 ggctcaacct gtggactgca ttggaaactg tcatacttga gtgccggagg ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg ggtggcagag ccattcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccctctga ccggaactta atcgttcctt tccttcggga 1020 cagaggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcctcagt agccagcatt taaggtgggc actctgggga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagatt gtgagatgga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct aactgcaaag 1440 aaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 111 <211> 1565 <212> DNA <213> Dialister_invisus <400> 111 atggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaaaag acggaaagag cttgctcttt tcagaattga gtggcaaacg ggtgagtaac 120 acgtaaacaa cctgccttca ggatggggac aacagacgga aacgactgct aataccgaat 180 aagttccaag agccgcatgg cccatggaag aaaaggtggc ctctacctgt aagctatcgc 240 ctgaagaggg gtttgcgtct gattagctgg ttggaggggt aacggcccac caaggcgacg 300 atcagtagcc ggtctgagag gatgaacggc cacactggaa ctgagacacg gtccagactc 360 ctacgggagg cagcagtggg gaatcttccg caatgggcga aagcctgacg gagcaacgcc 420 gcgtgagtga tgacggcctt cgggttgtaa aactctgtga tccgggacga aaaggcagag 480 tgcgaagaac aaactgcatt gacggtaccg gaaaagcaag ccacggctaa ctacgtgcca 540 gcagccgcgg taatacgtag gtggcaagcg ttgtccggaa ttattgggcg taaagcgcgc 600 gcaggcggct tcccaagtcc ctcttaaaag tgcggggctt aaccccgtga tgggaaggaa 660 actgggaagc tggagtatcg gagaggaaag tggaattcct agtgtagcgg tgaaatgcgt 720 agagattagg aagaacaccg gtggcgaagg cgactttctg gacgaaaact gacgctgagg 780 cgcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 840 gatactaggt gtaggaggta tcgacccctc ctgtgccgga gttaacgcaa taagtatccc 900 gcctgggaag tacgatcgca agattaaaac tcaaaggaat tgacggggcc cgcacaagcg 960 gtggagtatg tggtttaatt cgacgcaacg cgaagaacct taccaggtct tgacattgat 1020 cgcgatctgc agaaatgcgg agttcttctt cggaagacga gaaaacaggt ggtgcacggc 1080 tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc aacccctatc 1140 atttgttacc agcacgtaaa ggtggggact caaatgagac cgccgcggac aacgcggagg 1200 aaggcgggga cgacgtcaag tcatcatgcc ccttatgacc tgggctacac acgtactaca 1260 atgggtgtca acaaagagaa gcgaacccgc gaggaagagc aaacctcaaa aacacacccc 1320 cagttcagat cgcaggctgc aacccgcctg cgtgaagtag gaatcgctag taatcgcggg 1380 tcagcatacc gcggtgaata cgttcccggg ccttgtacac accgcccgtc acactatgag 1440 agtcagaaac acccgaagcc ggtgaggtaa ccgcaaggag ccagccgtcg aaggcggagc 1500 tgatgattgg agtgaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct 1560 ccttt 1565 <210> 112 <211> 1566 <212> DNA <213> Dialister_invisus <400> 112 atggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaaaag agggaaagag cttgctcttt ccggaattga gtggcaaacg ggtgagtaac 120 acgtaaacaa cctgccttca ggatggggac aacagacgga aacgactgct aataccgaat 180 aagttccaag agccgcatgg cccatggaag aaaaggtggc ctctacctgt aagctatcgc 240 ctgaagaggg gtttgcgtct gattagctgg ttggaggggt aacggcccac caaggcgacg 300 atcagtagcc ggtctgagag gatgaacggc cacactggaa ctgagacacg gtccagactc 360 ctacgggagg cagcagtggg gaatcttccg caatgggcga aagcctgacg gagcaacgcc 420 gcgtgagtga tgacggcctt cgggttgtaa aactctgtga tccgggacga aaaggcagag 480 tgcgaagaac aaactgcatt gacggtaccg gaaaagcaag ccacggctaa ctacgtgcca 540 gcagccgcgg taatacgtag gtggcaagcg ttgtccggaa ttattgggcg taaagcgcgc 600 gcaggcggct tcccaagtcc ctcttaaaag tgcggggctt aaccccgtga tgggaaggaa 660 actgggaagc tggagtatcg gagaggaaag tggaattcct agtgtagcgg tgaaatgcgt 720 agagattagg aagaacaccg gtggcgaagg cgactttctg gacgaaaact gacgctgagg 780 cgcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 840 gatactaggt gtaggaggta tcgacccctc ctgtgccgga gttaacgcaa taagtatccc 900 gcctgggaag tacgatcgca agattaaaac tcaaaggaat tgacgggggc ccgcacaagc 960 ggtggagtat gtggtttaat tcgacgcaac gcgaagaacc ttaccaggtc ttgacattga 1020 tcgcgatctg cagaaatgcg gagttcttct tcggaagacg agaaaacagg tggtgcacgg 1080 ctgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccctat 1140 catttgttac cagcacgtaa aggtggggac tcaaatgaga ccgccgcgga caacgcggag 1200 gaaggcgggg acgacgtcaa gtcatcatgc cccttatgac ctgggctaca cacgtactac 1260 aatgggtgtc aacaaagaga agcgaacccg cgaggaagag caaacctcaa aaacacaccc 1320 ccagttcaga tcgcaggctg caacccgcct gcgtgaagta ggaatcgcta gtaatcgcgg 1380 gtcagcatac cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacactatga 1440 gagtcagaaa cacccgaagc cggtgaggta accgcaagga gccagccgtc gaaggcggag 1500 ctgatgattg gagtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc 1560 tccttt 1566 <210> 113 <211> 1566 <212> DNA <213> Dialister_invisus <400> 113 atggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaaaag acggaaagag cttgctcttt tcagaattga gtggcaaacg ggtgagtaac 120 acgtaaacaa cctgccttca ggatggggac aacagacgga aacgactgct aatgccgaat 180 aagttccaag agccgcatgg cccatggaag aaaaggtggc ctctacctgt aagctatcgc 240 ctgaagaggg gtttgcgtct gattagctgg ttggaggggt aacggcccac caaggcgacg 300 atcagtagcc ggtctgagag gatgaacggc cacactggaa ctgagacacg gtccagactc 360 ctacgggagg cagcagtggg gaatcttccg caatgggcga aagcctgacg gagcaacgcc 420 gcgtgagtga tgacggcctt cgggttgtaa aactctgtga tccgggacga aaaggcagag 480 tgcgaagaac aaactgcatt gacggtaccg gaaaagcaag ccacggctaa ctacgtgcca 540 gcagccgcgg taatacgtag gtggcaagcg ttgtccggaa ttattgggcg taaagcgcgc 600 gcaggcggct tcccaagtcc ctcttaaaag tgcggggctt aaccccgtga tgggaaggaa 660 actgggaagc tggagtatcg gagaggaaag tggaattcct agtgtagcgg tgaaatgcgt 720 agagattagg aagaacaccg gtggcgaagg cgactttctg gacgaaaact gacgctgagg 780 cgcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 840 gatactaggt gtaggaggta tcgacccctc ctgtgccgga gttaacgcaa taagtatccc 900 gcctgggaag tacgatcgca agattaaaac tcaaaggaat tgacgggggc ccgcacaagc 960 ggtggagtat gtggtttaat tcgacgcaac gcgaagaacc ttaccaggtc ttgacattga 1020 tcgcgatctg cagaaatgcg gagttcttct tcggaagacg agaaaacagg tggtgcacgg 1080 ctgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccctat 1140 catttgttac cagcacgtaa aggtggggac tcaaatgaga ccgccgcgga caacgcggag 1200 gaaggcgggg acgacgtcaa gtcatcatgc cccttatgac ctgggctaca cacgtactac 1260 aatgggtgtc aacaaagaga agcgaacccg cgaggaagag caaacctcaa aaacacaccc 1320 ccagttcaga tcgcaggctg caacccgcct gcgtgaagta ggaatcgcta gtaatcgcgg 1380 gtcagcatac cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacactatga 1440 gagtcagaaa cacccgaagc cggtgaggta accgcaagga gccagccgtc gaaggcggag 1500 ctgatgattg gagtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc 1560 tccttt 1566 <210> 114 <211> 1527 <212> DNA <213> Dorea_formicigenerans <400> 114 acgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcac ataagttcga ttcttcggat gaagactttt gtgactgagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagctagaaa tggctgctaa 180 taccgcataa gaccacagta ctgcatggta cagtggtaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgaagg 420 atgaagtatt tcggtatgta aacttctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctgtgca agtctgaagt gaaaggcatg 600 ggctcaacct gtggactgct ttggaaactg tgcagctaga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtagcaaag ctattcggtg 840 ccgcagctaa cgcaataagc agtccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc tgatcttgac atcccgatga ccgcttcgta atggaagttt ttcttcggaa 1020 catcggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcttcagt agccagcatt aaggatgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aggcagagcc gcgaggccga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgca gatcagaatg ctgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 115 <211> 1527 <212> DNA <213> Dorea_formicigenerans <400> 115 acgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcac ttaagtttga ttcttcggat gaagactttt gtgactgagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttagaaa tggctgctaa 180 taccgcataa gaccacagta ctgcatggta cagtggtaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgaagg 420 atgaagtatt tcggtatgta aacttctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctgtgca agtctgaagt gaaaggcatg 600 ggctcaacct gtggactgct ttggaaactg tgcagctaga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtagcaaag ctattcggtg 840 ccgcagctaa cgcaataagc agtccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc tgatcttgac atcccgatga ccgcttcgta atggaagctt ttcttcggaa 1020 catcggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcttcagt agccagcatt aaggatgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aagcagagcc gcgaggccga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgca gatcagaatg ctgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 116 <211> 1527 <212> DNA <213> Dorea_formicigenerans <400> 116 acgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcac ttaagtttga ttcttcggat gaagactttt gtgactgagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttagaaa tggctgctaa 180 taccgcataa gaccacagta ctgcatggta cagtggtaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgaagg 420 atgaagtatt tcggtatgta aacttctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctgtgca agtctgaagt gaaaggcatg 600 ggctcaacct gtggactgct ttggaaactg tgcagctaga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtagcaaag ctattcggtg 840 ccgcagctaa cgcaataagc agtccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc tgatcttgac atcccgatga ccgcttcgta atggaagttt ttcttcggaa 1020 catcggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatattcagt agccagcatt taggatgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aggcagagcc gcgaggccga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgca gatcagaatg ctgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 117 <211> 1527 <212> DNA <213> Dorea_formicigenerans <400> 117 acgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcac ttaagtttga ttcttcggat gaagactttt gtgactgagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttagaaa tggctgctaa 180 taccgcataa gaccacagta ctgcatggta cagtggtaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgaagg 420 atgaagtatt tcggtatgta aacttctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctgtgca agtctgaagt gaaaggcatg 600 ggctcaacct gtggactgct ttggaaactg tgcagctaga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtagcaaag ctattcggtg 840 ccgcagctaa cgcaataagc agtccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc tgatcttgac atcccgatga ccgcttcgta atggaagctt ttcttcggaa 1020 catcggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcttcagt agccagcatt taggatgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aggcagagcc gcgaggccga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgca gatcagaatg ctgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 118 <211> 1296 <212> DNA <213> Dorea_formicigenerans <400> 118 tatgagatgg acccgcgtct gattaggtag ttggtgaggt aacggcccac caagccgacg 60 atcagtagcc gacctgagag ggtgaccggc cacattggga ctgagacacg gcccagactc 120 ctacgggagg cagcagtggg gaatattgca caatgggcga aagcctgatg cagcgacgcc 180 gcgtgaagga tgaagtattt cggtatgtaa acttctatca gcagggaaga aaatgacggt 240 acctgactaa gaagccccgg ctaactacgt gccagcagcc gcggtaatac gtagggggca 300 agcgttatcc ggatttactg ggtgtaaagg gagcgtagac ggctgtgcaa gtctgaagtg 360 aaaggcatgg gctcaacctg tggactgctt tggaaactgt gcagctagag tgtcggagag 420 gtaagtggaa ttcctagtgt agcggtgaaa tgcgtagata ttaggaggaa caccagtggc 480 gaaggcggct tactggacga tgactgacgt tgaggctcga aagcgtgggg agcaaacagg 540 attagatacc ctggtagtcc acgccgtaaa cgatgactgc taggtgtcgg gtagcaaagc 600 tattcggtgc cgcagctaac gcaataagca gtccacctgg ggagtacgtt cgcaagaatg 660 aaactcaaag gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag 720 caacgcgaag aaccttacct gatcttgaca tcccgatgac cgcttcgtaa tggaagtttt 780 tcttcggaac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 840 gggttaagtc ccgcaacgag cgcaaccctt atcttcagta gccagcattt aggatgggca 900 ctctggagag actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg 960 ccccttatga ccagggctac acacgtgcta caatggcgta aacaaaggga ggcagagccg 1020 cgaggccgag caaatctcaa aaataacgtc tcagttcgga ttgtagtctg caactcgact 1080 acatgaagct ggaatcgcta gtaatcgcag atcagaatgc tgcggtgaat acgttcccgg 1140 gtcttgtaca caccgcccgt cacaccatgg gagtcagtaa cgcccgaagt cagtgaccca 1200 accgaaagga gggagctgcc gaaggtggga ccgataactg gggtgaagtc gtaacaaggt 1260 agccgtatcg gaaggtgcgg ctggatcacc tccttt 1296 <210> 119 <211> 1527 <212> DNA <213> Dorea_formicigenerans <400> 119 acgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcac ataagttcga ttcttcggat gaagactttt gtgactgagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagctagaaa tggctgctaa 180 taccgcataa gaccacagta ctgcatggta cagtggtaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgaagg 420 atgaagtatt tcggtatgta aacttctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggctgtgca agtctgaagt gaaaggcatg 600 ggctcaacct gtggactgct ttggaaactg tgcagctaga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg atgactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgactg ctaggtgtcg ggtagcaaag ctattcggtg 840 ccgcagctaa cgcaataagc agtccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc tgatcttgac atcccgatga ccgcttcgta atggaagctt ttcttcggaa 1020 catcggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcttcagt agccagcatt taggatgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aagcagagcc gcgaggccga 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgca gatcagaatg ctgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgaaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 120 <211> 1424 <212> DNA <213> Eubacterium hallii <400> 120 ctgagtggcg gacgggtgag taacgcgtgg gtaacctgcc ctgtacaggg ggataacagc 60 tggaaacggc tgctaatacc gcataagcgc acgaggagac atctccttgt gtgaaaaact 120 ccggtggtac aggatgggcc cgcgtctgat tagctggttg gcagggtaac ggcctaccaa 180 ggcaacgatc agtagccggt ctgagaggat gaacggccac attggaactg agacacggtc 240 caaactccta cgggaggcag cagtggggaa tattgcacaa tgggggaaac cctgatgcag 300 caacgccgcg tgagtgaaga agtatttcgg tatgtaaagc tctatcagca gggaagataa 360 tgacggtacc tgactaagaa gctccggcta aatacgtgcc agcagccgcg gtaatacgta 420 tggagcaagc gttatccgga tttactgggt gtaaagggtg cgtaggtggc agtgcaagtc 480 agatgtgaaa ggccggggct caaccccgga gctgcatttg aaactgctcg gctagagtac 540 aggagaggca ggcggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac 600 cagtggcgaa ggcggcctgc tggactgtta ctgacactga ggcacgaaag cgtggggagc 660 aaacaggatt agataccctg gtagtccacg ccgtaaacga tgaatactag gtgtcggggc 720 cgtataggct tcggtgccgc cgctaacgca gtaagtattc cacctgggga gtacgttcgc 780 aagaatgaaa ctcaaaggaa ttgacgggga cccgcacaag cggtggagca tgtggtttaa 840 ttcgaagcaa cgcgaagaac cttaccaggt cttgacatcc ttctgaccgc accttaatcg 900 gtgctttcct tcgggacaga agagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg 960 agatgttggg ttaagtcccg caacgagcgc aacccctatc ttcagtagcc agcaggtaag 1020 gctgggcact ctggagagac tgccagggat aacctggagg aaggtgggga cgacgtcaaa 1080 tcatcatgcc ccttatgatc tgggcgacac acgtgctaca atggcggtca cagagtgagg 1140 cgaacccgcg agggggagca aaccacaaaa aggccgtccc agttcggact gtagtctgca 1200 acccgactac acgaagctgg aatcgctagt aatcgcgaat cagaatgtcg cggtgaatac 1260 gttcccgggt cttgtacaca ccgcccgtca caccatggga gtcggaaatg cccgaagcca 1320 gtgacccaac cttttggagg gagctgtcga aggtggagcc ggtaactggg gtgaagtcgt 1380 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc cttt 1424 <210> 121 <211> 1529 <212> DNA <213> Ruminococcaceae_bacterium_D16 <400> 121 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggagt gcctttgaaa gaggattcgt ccaattgata aggttactta gtggcggacg 120 ggtgagtaac gcgtgaggaa cctgccttgg agtggggaat aacacagtga aaattgtgct 180 aataccgcat aatgcagttg ggccgcatgg ctctgactgc caaagattta tcgctctgag 240 atggcctcgc gtctgattag ctagttggtg gggtaacggc ccaccaaggc gacgatcagt 300 agccggactg agaggttggc cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg gcgcaagcct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttcttaggg acgaagcaag tgacggtacc 480 taaggaataa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc 540 gttatccgga tttactgggt gtaaagggcg tgtaggcggg attgcaagtc agatgtgaaa 600 accacgggct caacctgtgg cctgcatttg aaactgtagt tcttgagtac tggagaggca 660 gacggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagtggcgaa 720 ggcggtctgc tggacagcaa ctgacgctga ggcgcgaaag cgtggggagc aaacaggatt 780 agataccctg gtagtccacg ctgtaaacga tggatactag gtgtgggggg tctgacccct 840 tccgtgccgc agttaacaca ataagtatcc cacctgggga gtacgatcgc aaggttgaaa 900 ctcaaaggaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa ttcgaagcaa 960 cgcgaagaac cttaccaggg cttgacatcc cgaggcccgg tctagagata gacctttctc 1020 ttcggagacc tcggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg 1080 ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ctacgcaaga gcactctagc 1140 gagactgccg ttgacaaaac ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgtcctgggc cacacacgta ctacaatggt ggttaacaga gggaggcaat accgcgaggt 1260 ggagcaaacc cctaaaagcc atcccagttc ggattgcagg ctgcaacccg cctgcatgaa 1320 gttggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttcc cgggccttgt 1380 acacaccgcc cgtcacacca tgagagtcgg gaacacccga agtccgtagc ctaaccgcaa 1440 ggggggcgcg gccgaaggtg ggttcgataa ttggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 122 <211> 1544 <212> DNA <213> Streptococcus vestibularis <400> 122 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataaca ttggaaacga tagctaatac cgcataacaa 180 tgggtgacac atgtcattta tttgaaaggg gcaattgctc cactacaaga tggacctgcg 240 ttgtattagc tagtaggtga ggtaacggct cacctaggcg acgatacata gccgacctga 300 gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg aggcagcagt 360 aggaatcttc ggcaatgggg gcaaccctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagtcaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtag cttaaccgag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggag 780 cgaacaggat tagataccct ggtagtccac gccgtaaacg atgagtgcta ggtgttggat 840 cctttccggg attcagtgcc gcagctaacg cattaagcac tccgcctggg gagtacgacc 900 gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag catgtggttt 960 aattcgaagc aacgcgaaga accttaccag gtcttgacat cccgatgcta tttctagaga 1020 tagaaagtta cttcggtaca tcggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattca 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcaagct aatctcttaa agaccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 123 <211> 1544 <212> DNA <213> Streptococcus vestibularis <400> 123 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 124 <211> 1543 <212> DNA <213> Streptococcus vestibularis <400> 124 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgtcgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagtaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccgtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcaagct aatctcttaa agccaatctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cttttggagc cagccgccta aggtggggta gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1543 <210> 125 <211> 1542 <212> DNA <213> Streptococcus vestibularis <400> 125 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggtgacac atgtcattat ttgaaagggg caattgctcc actacaagat ggacctgcgt 240 tgtattagct agtaggtgag gtaacggctc acctaggcga cgatacatag ccgacctgag 300 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta 360 gggaatcttc ggcaatgggg gcaaccctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagtcaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtag cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt 540 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg tttgataagt 600 ctgaagttaa aggctgtggc tcaaccatag ttcgctttgg aaactgtcaa acttgagtgc 660 agaaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac 720 cggtggcgaa agcggctctc tggtctgtaa ctgacgctga ggctcgaaag cgtggggagc 780 gaacaggatt agataccctg gtagtccacg ccgtaaacga tgagtgctag gtgttggatc 840 ctttccggga ttcagtgccg cagctaacgc attaagcact ccgcctgggg agtacgaccg 900 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta 960 attcgaagca acgcgaagaa ccttaccagg tcttgacatc ccgatgctat ttctagagat 1020 agaaagttac ttcggtacat cggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 1080 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcattcag 1140 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat 1200 catcatgccc cttatgacct gggctacaca cgtgctacaa tggttggtac aacgagttgc 1260 gagtcggtga cggcaagcta atctcttaaa gccaatctca gttcggattg taggctgcaa 1320 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg 1380 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg 1440 tgaggtaacc ttttggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta 1500 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tt 1542 <210> 126 <211> 1544 <212> DNA <213> Streptococcus vestibularis <400> 126 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 127 <211> 1544 <212> DNA <213> Streptococcus vestibularis <400> 127 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt gaatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 128 <211> 1544 <212> DNA <213> Streptococcus thermophilus <400> 128 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctggg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgaagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tgggtcacct cctt 1544 <210> 129 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 129 atgaaagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtag 60 aacgctgaag agaggagctt gctcttcttg gatgagttgc gaacgggtga gtaacgcgta 120 ggtaacctgc cttgtagcgg gggataacta ttggaaacga tagctaatac cgcataacaa 180 tggatgacac atgtcattta tttgaaaggg gcaattgctc cactacaaga tggacctgcg 240 ttgtattagc tagtaggtga ggtaatggct cacctaggcg acgatacata gccgacctga 300 gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg aggcagcagt 360 agggaatctt cggcaatggg ggcaaccctg accgagcaac gccgcgtgag tgaagaaggt 420 tttcggatcg taaagctctg ttgtaagtca agaacgggtg tgagagtgga aagttcacac 480 tgtgacggta gcttaccaga aagggacggc taactacgtg ccagcagccg cggtaatacg 540 taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg gtttgataag 600 tctgaagtta aaggctgtgg ctcaaccata gttcgctttg gaaactgtca aacttgagtg 660 cagaagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata tggaggaaca 720 ccggtggcga aagcggctca ctggtctgta actgacgctg aggctcgaaa gcgtggggag 780 cgaacaggat tagataccct ggtagtccac gccgtaaacg atgagtgcta ggtgttggat 840 cctttccggg attcagtgcc gcagctaacg cattaagcac tccgcctggg gagtacgacc 900 gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag catgtggttt 960 aattcgaagc aacgcgaaga accttaccag gtcttgacat cccgatgcta tttctagaga 1020 tagaaagtta cttcggtaca tcggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattca 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcgagct aatctcttaa agccaatctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cttttggagc cagccgccta aggtgggaca gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1543 <210> 130 <211> 1544 <212> DNA <213> Streptococcus thermophilus <400> 130 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 131 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 131 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctggg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggtcacctc ctt 1543 <210> 132 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 132 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtgggcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattca 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcgagct aatctcttaa agccaatctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cttttggagc cagccgccta aggtgggaca gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct gggtcacctc ctt 1543 <210> 133 <211> 1408 <212> DNA <213> Prevotella buccae <400> 133 cgtatccaac cttcccgcga ccaagggata acctgccgaa aggcagacta ataccttatg 60 tcctcctttg aaggcatctg acgaggagca aagatccgtc ggtcacggat ggggatgcgt 120 ccgattagct tgttggcggg gcaacggccc accaaggctt cgatcggtag gggttctgag 180 aggaaggccc cccacactgg aactgagaca cggtccagac tcctacggga ggcagcagtg 240 aggaatattg gtcaatgggc ggaagcctga accagccaag tagcgtgcag gatgacggcc 300 ctacgggttg taaactgctt ttatgcgggg ataaagttgc ccacgcgtgg gtttttgcag 360 gtaccgcatg aataaggacc ggctaattcc gtgccagcag ccgcggtaat acggaaggtc 420 cgggcgttat ccggatttat tgggtttaaa gggagcgcag gccgccgtgc aagcgtgccg 480 tgaaaagcag cggcccaacc gctgccctgc ggcgcgaact gcttggcttg agtgcgccgg 540 aagcgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aaccccgatt 600 gcgaaggcag cccgctgtgg cgccactgac gctgaggctc gaaggtgcgg gtatcgaaca 660 ggattagata ccctggtagt ccgcacggta aacgatggat acccgctgtc cggcccgtac 720 ggtctgggcg gccaagcgaa agcgttaagt atcccacctg gggagtacgc cggcaacggt 780 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 840 gatacgcgag gaaccttacc cgggcttgaa ttgcaggaga atgattcaga gatgatgaag 900 tccctcggga ctcctgtgaa ggtgctgcat ggttgtcgtc agctcgtgcc gtgaggtgtc 960 ggctcaagtg ccataacgag cgcaacccct ctccgcagtt gccatcgggt catgccgggc 1020 actctgcgga cactgccgcc gcaaggtgcg aggaaggtgg ggatgacgtc aaatcagcac 1080 ggcccttacg tccggggcca cacacgtgtt acaatggccg gcacagaggg ctgtccgcat 1140 gcaagtgcgg gcgaatcccc aaatccggtc ccagttcgga ctggggtctg caacccgacc 1200 ccacgaagct ggattcgcta gtaatcgcgc atcagccatg gcgcggtgaa tacgttcccg 1260 ggccttgtac acaccgcccg tcaagccatg aaagccgggg gtgcctgaag tccgtgaccg 1320 cgagggtcgg cctagggcaa aaccggtgat tggggctaag tcgtaacaag gtagccgtac 1380 cggaaggtgc ggctggaaca cctccttt 1408 <210> 134 <211> 1529 <212> DNA <213> Lachnospiraceae_bacterium_5_1_63FAA <400> 134 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaaacac cttatttgat tttcttcgga actgaagatt tggtgattga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgccctgt acagggggat aacagtcaga aatgactgct 180 aataccgcat aagaccacag caccgcatgg tgcaggggta aaaactccgg tggtacagga 240 tggacccgcg tctgattagc tggttggtga ggtaacggct caccaaggcg acgatcagta 300 gccggcttga gagagtgaac ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag 420 tgaagaagta tctcggtatg taaagctcta tcagcaggga agaaaatgac ggtacctgac 480 taagaagccc cggctaacta cgtgccagca gccgcggtaa tacgtagggg gcaagcgtta 540 tccggaatta ctgggtgtaa agggtgcgta ggtggtatgg caagtcagaa gtgaaaaccc 600 agggcttaac tctgggactg cttttgaaac tgtcagactg gagtgcagga gaggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacatcagt ggcgaaggcg 720 gcttactgga ctgaaactga cactgaggca cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt cggggccgta gaggcttcgg 840 tgccgcagcc aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta cctggtcttg acatccttct gaccggtcct taaccggacc tttccttcgg 1020 gacaggagag acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cctatcttta gtagccagca tataaggtgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgaccagggc tacacacgtg ctacaatggc gtaaacagag ggaagcagcc tcgtgagagt 1260 gagcaaatcc caaaaataac gtctcagttc ggattgtagt ctgcaactcg actacatgaa 1320 gctggaatcg ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag taacgcccga agtcagtgac ccaaccgtaa 1440 ggagggagct gccgaaggcg ggaccgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 135 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_8_1_57FAA <400> 135 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 136 <211> 1545 <212> DNA <213> Streptococcus_australis <400> 136 aatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa ggaaggagct tgctctttct ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg cctggtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 gtagatgttg catgatatct gcttgaaagg ggcaattgct ccactaccag atggacctgc 240 gttgtattag ctagttggtg aggtaacggc tcaccaaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg acggaagtct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagag aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt atcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttatcc ggatttattg ggcgtaaagc gagcgcaggc ggttagataa 600 gtctgaagtt aaaggctgtg gcttaaccat agtacgcttt ggaaactgtt taacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttggg 840 tcctttccgg gactcagtgc cgtagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tccctctgat cgctctagag 1020 atagagtttt ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggctggt acaacgagtc 1260 gcaagtcggt gacggcaagc taatctctta aagccagtct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttagga gccagccgcc taaggtggga tagatgattg gggtgaagtc 1500 gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctt 1545 <210> 137 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_4_1_37FAA <400> 137 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagca cttgaatgga attcttcgga aggaagctca agtgactgag tggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agcacacgtg atcgcatgat cgagtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtggg gtaacggccc accaaggcga cgatcagtag 300 ccggcctgag agggtgaacg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgaag 420 gatgaagtat ttcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcagtgc aagtctgaag tgaaagcccg 600 gggctcaacc ccgggactgc tttggaaact gtgcagctag agtgtcggag aggcaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttgctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc ggggagcaaa gctcttcggt 840 gccgcagcca acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catccctctg accggcaagt aatgttgcct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatcttcag tagccagcgg taaggccggg cactctggag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcagagt cgtgaggccg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 138 <211> 1544 <212> DNA <213> Streptococcus sanguis <400> 138 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg cctggtagcg ggggataact attggaaacg atagctaata ccgcatgata 180 ttaattatcg catgataatt aattgaaaga tgcaattgca tcactaccag atggacctgc 240 gttgtattag ctagttggtg aggtaacggc tcaccaaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg ggggaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagag aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt atcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggttagataa 600 gtctgaagtt aaaggctgtg gcttaaccat agtatgcttt ggaaactgtt taacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttagg 840 ccctttccgg ggcttagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tccctctgac cgctctagag 1020 atagagtttt ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattg 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggctggt acaacgagtc 1260 gcaagccggt gacggcaagc taatctctga aagccagtct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccgtaaggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 139 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_3_1_46FAA <400> 139 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 140 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_6_1_63FAA <400> 140 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca cttatcattg actcttcgga agatttgata tttgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata caggggaata acagttagaa atggctgcta 180 atgccgcata agcgcacagg accgcatggt ctggtgtgaa aaactgaggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccggcctgag agggtgaacg gccacattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgaag 420 gaagaagtat ctcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggaagagc aagtctgatg tgaaaggctg 600 gggcttaacc ccaggactgc attggaaact gtttttctag agtgccggag aggtaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac ggtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc ggggtgcaaa gcagttcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catctgcctg accgttcctt aaccggagct ttccttcggg 1020 acaggcaaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatccttag tagccagcag tccggctggg cactctaggg 1140 agactgccgg ggataacccg gaggaaggcg gggacgacgt caaatcatca tgccccttat 1200 gatttgggct acacacgtgc tacaatggcg taaacaaagg gaagcgaagc ggtgacgctt 1260 agcaaatctc aaaaataacg tcccagttcg gactgcagtc tgcaactcga ctgcacgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccttatg 1440 gagggagctg ccgaaggcgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 141 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_9_1_43BFAA <400> 141 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagca cttgaatgga attcttcgga aggaagctca agtgactgag tggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agcacacgtg atcgcatgat cgagtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtggg gtaatggccc accaaggcga cgatcagtag 300 ccggcctgag agggtgaacg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgaag 420 gatgaagtat ttcggtatgt aaacttctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcagtgc aagtctgaag tgaaagcccg 600 gggctcaacc ccgggactgc tttggaaact gtgcagctag agtgtcggag aggcaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttgctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc ggggagcaaa gctcttcggt 840 gccgcagcca acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catccctctg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatcttcag tagccagcgg taaggccggg cactctggag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcagagt cgtgaggccg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 142 <211> 1312 <212> DNA <213> Ruminococcus bromii <400> 142 atatcaaaga ttttatcgct tgaagatgga ctcgcgtccg attagttagt tggtgaggta 60 acggctcacc aagaccgcga tcggtagccg gactgagagg ttgaacggcc acattgggac 120 tgagacacgg cccagactcc tacgggaggc agcagtgggg gatattgcgc aatgggggca 180 accctgacgc agcaacgccg cgtgaaggat gaaggttttc ggattgtaaa cttcttttat 240 taaggacgaa acttgacggt acttaatgaa taagctccgg ctaactacgt gccagcagcc 300 gcggtaatac gtagggagca agcgttgtcc ggatttactg ggtgtaaagg gtgcgtaggc 360 ggctttgcaa gtcagatgtg aaatctatgg gctcaaccca taaactgcat ttgaaactgt 420 agagcttgag tgaagtagag gcaggcggaa ttccccgtgt agcggtgaaa tgcgtagaga 480 tggggaggaa caccagtggc gaaggcggcc tgctgggctt taactgacgc tgaggcacga 540 aagcgtgggt agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgattac 600 taggtgtggg gggtctgacc ccttccgtgc cggagttaac acaataagta atccacctgg 660 ggagtacggc cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcagtgga 720 gtatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca tccaactaac 780 gaagtagaga tacattaggt gcccttcggg gaaagttgag acaggtggtg catggttgtc 840 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cttgctatta 900 gttgctacgc aagagcactc taataggact gccgttgaca aaacggagga aggtggggac 960 gacgtcaaat catcatgccc cttatgacct gggctacaca cgtactacaa tggatgttaa 1020 cagagggaag caagacagcg atgtggagca aacccctaaa aacattctca gttcagattg 1080 caggctgcaa cccgcctgca tgaagatgga attgctagta atcgcggatc agcatgccgc 1140 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accatgggag ccggtaatac 1200 ccgaagtcag tagtccaacc tcgtgaggac gctgccgaag gtaggattgg cgactggggt 1260 gaagtcgtaa caaggtagcc gtatcggaag gtgcggctgg atcacctcct tt 1312 <210> 143 <211> 976 <212> DNA <213> Coprococcus_catus <220> <221> misc_feature <222> (974)..(976) <223> n is a, c, g, or t <400> 143 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacggacgat gaagagcttg cttttcaaag ttagtggcgg acgggtgagt aacgcgtggg 120 taacctgcct catacagggg gatagcagct ggaaacggct gataaaaccg cataagcgca 180 cagcatcgca tgatgcagtg tgaaaaactc cggtggtatg agatggaccc gcgtctgatt 240 agctggttgg tgaggtaacg gcccaccaag gcgacgatca gtagccggcc tgagagggtg 300 accggccaca ttgggactga gacacggccc aaactcctac gggaggcagc agtggggaat 360 attgcacaat gggggaaacc ctgatgcagc gacgccgcgt gaaggaagaa gtatctcggt 420 atgtaaactt ctatcagcag ggaagataat gacggtacct gactaagaag ccccggctaa 480 ctacgtgcca gcagccgcgg taatacgtag ggggcaagcg ttatccggat ttactgggtg 540 taaagggagc gtaggcggcg gagcaagtca gaagtgaaag cccggggctc aaccccggga 600 cggcttttga aactgccctg cttgatttca ggagaggtaa gcggaattcc tagtgtagcg 660 gtgaaatgcg tagatattag gaggaacacc agtggcgaag gcggcttact ggactgacaa 720 tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg tagtccacgc 780 cgtaaacgat gaatactagg tgtcgggggc tcataagagc tttcggtgcc gcagcaaacg 840 caataagtat tccacctggg gagtacgttc gcaagaatga aactcaaagg aattgacggg 900 gacccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag 960 gccttgacat cccnnn 976 <210> 144 <211> 1522 <212> DNA <213> Dysgonomonas_mossii <400> 144 agaagagttt gatcctggct caggatgaac gctagcgata ggcctaacac atgcaagtcg 60 aggggcagca tagagtagca atactttgat ggcgaccggc gcacgggtga gtaacacgta 120 tgcaacctac ctacatcagg ggaataaccc ggagaaattc ggactaatac cgcataatac 180 agggatgccg catggcaata tttgttaaag atttatcgga tgtagatggg catgcgttcc 240 attagctggt tggtaaggta acggcttacc aaggcaacga tggatagggg aactgagagg 300 tttgtccccc acactggaac tgagacacgg accagactcc tacgggaggc agcagtgagg 360 aatattggtc aatggacgag agtctgaacc agccaaatcg cgtgaaggaa gactgcccta 420 cgggttgtaa acttcttttg tacaggaata aaagacatta cgtgtagtgt attgcatgta 480 ctgtacgaat aagcatcggc taactccgtg ccagcagccg cggtaatacg gaggatgcga 540 gcgttatccg gatttattgg gtttaaaggg tgcgcaggcg ggattttaag tcagcggtga 600 aattttcagg ctcaacctga acactgccgt tgaaactggg attcttgagt atggatgaag 660 taggcggaat tcgttgtgta gcggtgacat gcttagatat aacgaggaac tccgattgcg 720 taggcagctt actaagccat aactgacgct caagcacgaa agcgtgggga tcaaacagga 780 ttagataccc tggtagtcca cgccgtaaac gatgattact agttgtttgc gatataccgt 840 aagtgactaa gcgaaagcga taagtaatcc acctggggag tacgccggca acggtgaaac 900 tcaaaggaat tgacgggggc ccgcacaagc ggaggaacat gtggtttaat tcgatgatac 960 gcgaggaacc ttacccgggc ttgaaatgta cctgaccgtc cttgaaaggg gacttctagc 1020 aatagcaggt atgtaggtgc tgcatggttg tcgtcagctc gtgccgtgag gtgtcggctt 1080 aagtgccata acgagcgcaa cccacattat tagttactaa caggttaagc tgaggactct 1140 aataagactg ccgtcgtaag atgcgaggaa ggtgtggatg acgtcaaatc agcacggccc 1200 ttacgtccgg ggcgacacac gtgttacaat gggaggtaca aagggctgct acctggtgac 1260 aggatgctaa tccccaaagc ctctcccagt tcggatcgga gtctgcaact cgactccgtg 1320 aagctggatt cgctagtaat cgcgcatcag ccatggcgcg gtgaatacgt tcccgggcct 1380 tgtacacacc gcccgtcaag ccatgggagc cgggggtatc tgaagtgcgt aaccgtaagg 1440 agcgtcctag ggtaaaactg gtgactgggg ctaagtcgta acaaggtagc cgtaccggaa 1500 ggtgcggctg gaacacctcc tt 1522 <210> 145 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_1_4_56FAA <400> 145 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagca ctttaccgga tttcttcggg atgaaagttt tgtgactgag tggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagg attgcatgat ccggtggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggagaggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gtttttctag agtgtcggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact gctaggtgtc gggaggcaaa gcctttcggt 840 gccgcagcaa acgcaataag cagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgcccttga catccggctg accggcgagt aatgtcgcct ttccttcggg 1020 acagccgaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatctttag tagccagcat ttcggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gggcagggct acacacgtgc tacaatggcg taaacaaagg gaggcaagcc tgcgagggtg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 146 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 146 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttac acggaggaag ttttcggatg gaatcggtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacggaacc gcatggttcc gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgcc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccccctgaa tatcttgtaa aaaagagatg ccttcgggac 1020 aggggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaggctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 147 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 147 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttat atcgaggaag ttttcggatg gaatcagtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacagcttc acatgaagca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgtc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccccctgac tctcctgtaa aagagtgagg ccttcgggac 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaagctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 148 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 148 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttac acagaggaag ttttcggatg gaatcggtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacggattc acatgaagca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgtc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tcccaatgac gcacctgtaa agaggtgttc ccttcggggc 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaagctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 149 <211> 1532 <212> DNA <213> Lachnospiraceae_bacterium_5_1_57FAA <400> 149 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagcg cctggccccg acttcttcgg aacgaggagc cttgcgactg agtggcggac 120 gggtgagtaa cgcgtgggca acctgccttg cactggggga taacagccag aaatggctgc 180 taataccgca taagaccgaa gcgccgcatg gcgcggcggc caaagccccg gcggtgcaag 240 atgggcccgc gtctgattag gtagttggcg gggtaacggc ccaccaagcc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaagatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggcgat gcaagccaga tgtgaaagcc 600 cggggctcaa ccccgggact gcatttggaa ctgcgtggct ggagtgtcgg agaggcaggc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcctgctgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga ctactaggtg tcgggtggca aggccattcg 840 gtgccgcagc aaacgcaata agtagtccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgatctt gacatcccga tgccaaagcg cgtaacgcgc tctttcttcg 1020 gaacatcggt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctatcttc agtagccagc attatggatg ggcactctgg 1140 agagactgcc agggagaacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgaccaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa cccgcgaggg 1260 tgggcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagtca gtaacgcccg aagccggtga cccaacccgt 1440 aagggaggga gccgtcgaag gtgggaccga taactggggt gaagtcgtaa caaggtagcc 1500 gtatcggaag gtgcggctgg atcacctcct tt 1532 <210> 150 <211> 1528 <212> DNA <213> Lachnospiraceae_bacterium_1_1_57FAA <400> 150 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gagcgaagca ctttgcttag attcttcgga tgaagaggat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttagaa atgactgcta 180 ataccgcata agaccacagc accgcatggt gcgggggtaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtaag gtaacggctt accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggatgggc aagtctgatg tgaaaacccg 600 gggctcaacc ccgggactgc attggaaact gttcatctag agtgctggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac agtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgact actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tagtccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctgctcttga catcccgctg accggacggt aatgcgtcct tcccttcggg 1020 gcagcggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcgg ccaggccggg cactctagag 1140 agactgccgg ggataacccg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gagcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagac cgcgaggtgg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggcgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 151 <211> 1529 <212> DNA <213> Lachnospiraceae_bacterium_2_1_58FAA <400> 151 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca ccttgacgga tttcttcgga ttgaagcctt ggtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggaaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 ctttctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccctctg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat tttcggatgg gcactctaga 1140 gagactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgaccagggc tacacacgtg ctacaatggc gtaaacaaag ggaagcgagc ccgcgagggg 1260 gagcaaatcc caaaaataac gtctcagttc ggattgtagt ctgcaactcg actacatgaa 1320 gctggaatcg ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag taacgcccga agtcagtgac ccaaccgcaa 1440 ggagggagct gccgaaggtg ggaccgataa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 152 <211> 1528 <212> DNA <213> Roseburia_hominis <400> 152 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttaattgat ttcttcggaa tgaagttttt gtgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttggaaa cgactgctaa 180 taccgcataa gcgcacagga ttgcatgatc cagtgtgaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattagcca gttggcgggg taacggccca ccaaagcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagcg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aagaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgcag gcggtacggc aagtctgatg tgaaatcccg 600 gggctcaacc ccggtactgc attggaaact gtcggactag agtgtcggag gggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gattactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc ggggagcatt gctcttcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catcccactg acaaagtatg taatgtactt tctcttcgga 1020 gcagtggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctattcttag tagccagcgg ttcggccggg cactctaggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gacttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaatcc cgcgaggggg 1260 agcaaatctc aaaaataacg tctcagttcg gactgtagtc tgcaactcga ctacacgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aatgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggcag gactgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 153 <211> 1528 <212> DNA <213> Roseburia_hominis <400> 153 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttaattgat ttcttcggaa tgaagttttt gtgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttggaaa cgactgctaa 180 taccgcataa gcgcacagga ttgcatgatc cagtgtgaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattagcca gttggcgggg taacggccca ccaaagcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagcg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aagaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgcag gcggtacggc aagtctgatg tgaaatcccg 600 gggctcaacc ccggtactgc attggaaact gtcggactag agtgtcggag gggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gattactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc ggggagcatt gctcttcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catcccactg acagagtatg taatgtactt tctcttcgga 1020 gcagtggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctattcttag tagccagcgg ttcggccggg cactctaggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gacttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaatcc cgcgaggggg 1260 agcaaatctc aaaaataacg tctcagttcg gactgtagtc tgcaactcga ctacacgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aatgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggcag gactgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 154 <211> 1528 <212> DNA <213> Roseburia_hominis <400> 154 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttaattgat ttcttcggaa tgaagttttt gtgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttggaaa cgactgctaa 180 taccgcataa gcgcacagga ttgcatgatc cagtgtgaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattagcca gttggcgggg taacggccca ccaaagcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagcg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aagaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgcag gcggtacggc aagtctgatg tgaaatcccg 600 gggctcaacc ccggtactgc attggaaact gtcggactag agtgtcggag gggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gattactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc ggggagcatt gctcttcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catcccactg acagagtatg taatgtactt tctcttcgga 1020 gcagtggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctattcttag tagccagcgg ttcggccggg cactctaggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gacttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaatcc cgcgaggggg 1260 agcaaatctc aaaaataacg tctcagttcg gactgtagtc tgcaactcga ctacacgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aatgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggcag gactgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 155 <211> 1528 <212> DNA <213> Roseburia_hominis <400> 155 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tttaattgat ttcttcggaa tgaagttttt gtgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgcctcatac agggggataa cagttggaaa cgactgctaa 180 taccgcataa gcgcacagga ttgcatgatc cggtgtgaaa aactccggtg gtatgagatg 240 gacccgcgtc tgattagcca gttggcgggg taacggccca ccaaagcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgagcg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aagaatgacg gtacctgact 480 aagaagcacc ggctaaatac gtgccagcag ccgcggtaat acgtatggtg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgcag gcggtacggc aagtctgatg tgaaatcccg 600 gggctcaacc ccggtactgc attggaaact gtcggactag agtgtcggag gggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gattactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc ggggagcatt gctcttcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catcccactg acagagtatg taatgtactt tctcttcgga 1020 gcagtggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctattcttag tagccagcgg ttcggccggg cactctaggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gacttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaatcc cgcgaggggg 1260 agcaaatctc aaaaataacg tctcagttcg gactgtagtc tgcaactcga ctacacgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aatgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggcag gactgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 156 <211> 1536 <212> DNA <213> Erysipelotrichaceae_bacterium_2_2_44A <400> 156 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagct tcaggaagct tgcttccaaa gagacttagt ggcgaacggg tgagtaacac 120 gtaggtaacc tgcccatgtg tccgggataa ctgctggaaa cggtagctaa aaccggatag 180 gtatacagag cgcatgctca gtatattaaa gcgcccatca aggcgtgaac atggatggac 240 ctgcggcgca ttagctagtt ggtgaggtaa cggcccacca aggcgatgat gcgtagccgg 300 cctgagaggg taaacggcca cattgggact gagacacggc ccaaactcct acgggaggca 360 gcagtaggga attttcgtca atgggggaaa ccctgaacga gcaatgccgc gtgagtgaag 420 aaggtcttcg gatcgtaaag ctctgttgta agtgaagaac ggctcataga ggaaatgcta 480 tgggagtgac ggtagcttac cagaaagcca cggctaacta cgtgccagca gccgcggtaa 540 tacgtaggtg gcaagcgtta tccggaatca ttgggcgtaa agggtgcgta ggtggcgtac 600 taagtctgta gtaaaaggca atggctcaac cattgtaagc tatggaaact ggtatgctgg 660 agtgcagaag agggcgatgg aattccatgt gtagcggtaa aatgcgtaga tatatggagg 720 aacaccagtg gcgaaggcgg tcgcctggtc tgtaactgac actgaggcac gaaagcgtgg 780 ggagcaaata ggattagata ccctagtagt ccacgccgta aacgatgaga actaagtgtt 840 ggaggaattc agtgctgcag ttaacgcaat aagttctccg cctggggagt atgcacgcaa 900 gtgtgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagtatg tggtttaatt 960 cgaagcaacg cgaagaacct taccaggcct tgacatggaa acaaataccc tagagatagg 1020 gggataatta tggatcacac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tgtcgcatgt taccagcatc aagttgggga 1140 ctcatgcgag actgccggtg acaaaccgga ggaaggtggg gatgacgtca aatcatcatg 1200 ccccttatgg cctgggctac acacgtacta caatggcgac cacaaagagc agcgacttgg 1260 tgacaagaag cgaatctcat aaaggtcgtc tcagttcgga ttgaagtctg caactcgact 1320 tcatgaagtc ggaatcgcta gtaatcgcag atcagcatgc tgcggtgaat acgttctcgg 1380 gccttgtaca caccgcccgt caaaccatgg gagtcagtaa tacccgaagc cggtggcata 1440 accgtaagga gtgagccgtc gaaggtagga ccgatgactg gggttaagtc gtaacaaggt 1500 atccctacgg gaacgtgggg atggatcacc tccttt 1536 <210> 157 <211> 1426 <212> DNA <213> Clostridium_citroniae <220> <221> misc_feature <222> (1422)..(1426) <223> n is a, c, g, or t <400> 157 tttgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagca atcagaatga aattttcgga tggatttctg gttgactgag tggcggacgg 120 gtgagtaacg cgtggataac ctgcctcaca ctgggggata acagttagaa atggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtgtgagat 240 ggatccgcgt ctgattagtt agttggcggg gtaacggccc accaagacag cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagt 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcgaagc aagtctgaag tgaaaaccca 600 gggctcaacc ctgggactgc tttggaaact gttttgctag agtgtcggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gataactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat gctaggtgtt ggggggcaaa gcccttcggt 840 gccgtcgcaa acgcaataag cattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catccccctg accggtcagt aaagtgacct ttccttcggg 1020 acaggggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatccttag tagccagcag gtaaagctgg gcactctagg 1140 gagactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgatttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcgacc ctgcgaaggc 1260 aagcaaatcc caaaaataac gtcccagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag caacgcccga annnnn 1426 <210> 158 <211> 1530 <212> DNA <213> Flavonifractor_plautii <400> 158 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggggt gctcatgacg gaggattcgt ccaatggatt gagttaccta gtggcggacg 120 ggtgagtaac gcgtgaggaa cctgccttgg agaggggaat aacactccga aaggagtgct 180 aataccgcat gaagcagttg ggtcgcatgg ctctgactgc caaagattta tcgctctgag 240 atggcctcgc gtctgattag ctagtaggcg gggtaacggc ccacctaggc gacgatcagt 300 agccggactg agaggttgac cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg gcgcaagcct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttgtcgggg acgaaacaaa tgacggtacc 480 cgacgaataa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc 540 gttatccgga tttactgggt gtaaagggcg tgtaggcggg attgcaagtc agatgtgaaa 600 actgggggct caacctccag cctgcatttg aaactgtagt tcttgagtgc tggagaggca 660 atcggaattc cgtgtgtagc ggtgaaatgc gtagatatac ggaggaacac cagtggcgaa 720 ggcggattgc tggacagtaa ctgacgctga ggcgcgaaag cgtggggagc aaacaggatt 780 agataccctg gtagtccacg ccgtaaacga tggatactag gtgtgggggg tctgaccccc 840 tccgtgccgc agttaacaca ataagtatcc cacctgggga gtacgatcgc aaggttgaaa 900 ctcaaaggaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa ttcgaagcaa 960 cgcgaagaac cttaccaggg cttgacatcc cactaacgag gcagagatgc gttaggtgcc 1020 cttcggggaa agtggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt attgttagtt gctacgcaag agcactctag 1140 cgagactgcc gttgacaaaa cggaggaagg tggggacgac gtcaaatcat catgcccctt 1200 atgtcctggg ccacacacgt actacaatgg tggttaacag agggaggcaa taccgcgagg 1260 tggagcaaat ccctaaaagc catcccagtt cggattgcag gctgaaaccc gcctgtatga 1320 agttggaatc gctagtaatc gcggatcagc atgccgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcacacc atgagagtcg ggaacacccg aagtccgtag cctaaccgca 1440 aggagggcgc ggccgaaggt gggttcgata attggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 159 <211> 1530 <212> DNA <213> Lachnospiraceae_bacterium_7_1_58FAA <400> 159 tattgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggggt gctcatgacg gaggattcgt ccaacggatt gagttaccta gtggcggacg 120 ggtgagtaac gcgtgaggaa cctgccttgg agaggggaat aacactccga aaggagtgct 180 aataccgcat gatgcagttg ggtcgcatgg ctctgactgc caaagattta tcgctctgag 240 atggcctcgc gtctgattag ctagtaggcg gggtaacggc ccacctaggc gacgatcagt 300 agccggactg agaggttgac cggccacatt gggactgaga cacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg gcgcaagcct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttgtcgggg acgaaacaaa tgacggtacc 480 cgacgaataa gccacggcta actacgtgcc agcagccgcg gtaatacgta ggtggcaagc 540 gttatccgga tttactgggt gtaaagggcg tgtaggcggg attgcaagtc agatgtgaaa 600 actgggggct caacctccag cctgcatttg aaactgtagt tcttgagtgc tggagaggca 660 atcggaattc cgtgtgtagc ggtgaaatgc gtagatatac ggaggaacac cagtggcgaa 720 ggcggattgc tggacagtaa ctgacgctga ggcgcgaaag cgtggggagc aaacaggatt 780 agataccctg gtagtccacg ccgtaaacga tggatactag gtgtgggggg tctgaccccc 840 tccgtgccgc agttaacaca ataagtatcc cacctgggga gtacgatcgc aaggttgaaa 900 ctcaaaggaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa ttcgaagcaa 960 cgcgaagaac cttaccaggg cttgacatcc cactaacgaa gcagagatgc attaggtgcc 1020 cttcggggaa agtggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt attgttagtt gctacgcaag agcactctag 1140 cgagactgcc gttgacaaaa cggaggaagg tggggacgac gtcaaatcat catgcccctt 1200 atgtcctggg ccacacacgt actacaatgg tggttaacag agggaggcaa taccgcgagg 1260 tggagcaaat ccctaaaagc catcccagtt cggattgcag gctgaaaccc gcctgtatga 1320 agttggaatc gctagtaatc gcggatcagc atgccgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcacacc atgagagtcg ggaacacccg aagtccgtag cctaaccgca 1440 aggagggcgc ggccgaaggt gggttcgata attggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 160 <211> 1587 <212> DNA <213> Erysipelotrichaceae_bacterium_6_1_45 <220> <221> misc_feature <222> (215)..(314) <223> n is a, c, g, or t <400> 160 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300 nnnnnnnnnn nnnngaggta acggctcacc aaggcgatga tgcgtagccg gcctgagagg 360 gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc agcagtaggg 420 aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa gaaggtcttc 480 ggatcgtaaa gctctgttgt aagtgaagaa cggatcatag aggaaatgct atgggagtga 540 cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta atacgtaggt 600 ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta ctaagtctgt 660 agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg gagtgcagaa 720 gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag gaacaccagt 780 ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg gggagcaaat 840 aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt tggaggaatt 900 cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca agtgtgaaac 960 tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat tcgaagcaac 1020 gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag ggggataatt 1080 atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1140 tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg actcatgcga 1200 gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1260 gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca gtgatgtgaa 1320 gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac ttcatgaagt 1380 cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg ggccttgtac 1440 acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat aaccgtaagg 1500 agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg tatccctacg 1560 ggaacgtggg gatggatcac ctccttt 1587 <210> 161 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_6_1_45 <400> 161 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgtccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggctcacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcttggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 162 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_6_1_45 <400> 162 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggatcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 163 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_6_1_45 <400> 163 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggatcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 164 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_6_1_45 <400> 164 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga tgcaaatgtt ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 165 <211> 997 <212> DNA <213> Erysipelotrichaceae_bacterium_21_3 <400> 165 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacat 997 <210> 166 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_21_3 <400> 166 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga tgcaaatgtt ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 167 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_21_3 <400> 167 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga tgcaaatgtt ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 168 <211> 1537 <212> DNA <213> Erysipelotrichaceae_bacterium_21_3 <400> 168 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtt tcgaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga tgcaaatgtt ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcgg ccacaaagag cagcgacaca 1260 gtgatgtgaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 169 <211> 1536 <212> DNA <213> Haemophilus parainfluenzae <400> 169 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcttaaca catgcaagtc 60 gaacggtaac ataaagaagc ttgcttcttt gatgacgagt ggcggacggg tgagtaatgc 120 ttgggaatct agcttatgga gggggataac tacgggaaac tgtagctaat accgcgtaga 180 atcgggagat gaaagtgtgg gaccttcggg ccacatgcca taggatgagc ccaagtggga 240 ttaggtagtt ggtgaggtaa aggctcacca agccgacgat ctctagctgg tctgagagga 300 tgaccagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcgca atgggggcaa ccctgacgca gccatgccgc gtgaatgaag aaggccttcg 420 ggttgtaaag ttctttcggt agcgaggaag gcatttagtt taataaactg gatgattgac 480 gttaactaca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcgagcgtta atcggaataa ctgggcgtaa agggcacgca ggcggtgact taagtgaggt 600 gtgaaagccc cgggcttaac ctgggaattg catttcatac tgggtcgcta gagtacttta 660 gggaggggta gaattccacg tgtagcggtg aaatgcgtag agatgtggag gaataccgaa 720 ggcgaaggca gccccttggg aatgtactga cgctcatgtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttggggg ttgagcttta 840 agtttggcgc ccgtagctaa cgtgataaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tactcttgac atccagagaa cattccagag atggattggt 1020 gccttcggga actctgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcgat ttggtcggga 1140 actcaaagga gactgccggt gataaaccgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg agtagggcta cacacgtgct acaatggcgt atacagaggg aagcgagagt 1260 gcgagctgga gcgaatctca caaagtacgt ctaagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgca aatcagaatg ttgcggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gtaccagaag tagatagctt 1440 aaccttcggg ggggcgttta ccacggtatg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 170 <211> 1547 <212> DNA <213> Streptococcus parasanguis <400> 170 taatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaat acatgcaagt 60 agaacgctga agcttggtgc ttgcaccgag cggaggagtt gcgaacgggt gagtaacgcg 120 taggtaacct gcctcttagc gggggataac tattggaaac gatagctaat accgcataaa 180 agtcgacatt gcatgatgtt gacttgaaag gtgcaactgc atcactaaga gatggacctg 240 cgttgtatta gctagttggt gaggtaacgg ctcaccaagg cgacgataca tagccgacct 300 gagagggtga tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca 360 gtagggaatc ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag 420 gttttcggat cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac 480 actgtgacgg taacttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata 540 cgtaggtccc gagcgttatc cggatttatt gggcgtaaag cgagcgcagg cggttagata 600 agtctgaagt taaaggctgt ggcttaacca tagtacgctt tggaaactgt ttaacttgag 660 tgcagaaggg gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa 720 caccggtggc gaaagcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg 780 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taggtgttgg 840 gtcctttccg ggactcagtg ccgcagctaa cgcattaagc actccgcctg gggagtacga 900 ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt 960 ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga 1020 gatagagctt tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt 1080 cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt 1140 tagttgggca ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca 1200 aatcatcatg ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt 1260 cgcgagtcgg tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg 1320 caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat 1380 acgttcccgg gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt 1440 cggtgaggta accttttagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt 1500 cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctccttt 1547 <210> 171 <211> 1546 <212> DNA <213> Streptococcus parasanguis <400> 171 taatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaat acatgcaagt 60 agaacgctga agcttggtgc ttgcaccgag cggaggagtt gcgaacgggt gagtaacgcg 120 taggtaacct gcctcttagc gggggataac tattggaaac gatagctaat accgcataaa 180 agtcgacatt gcatgatgtt gacttgaaag gtgcaaatgc atcactgaga gatggacctg 240 cgttgtatta gctagttggt gaggtaacgg ctcaccaagg cgacgataca tagccgacct 300 gagagggtga tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca 360 gtagggaatc ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag 420 gttttcggat cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac 480 actgtgacgg taacttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata 540 cgtaggtccc gagcgttatc cggatttatt gggcgtaaag cgagcgcagg cggttagata 600 agtctgaagt taaaggctgt ggcttaacca tagtacgctt tggaaactgt ttaacttgag 660 tgcagaaggg gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa 720 caccggtggc gaaagcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg 780 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taggtgttgg 840 tcctttccgg gactcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tccctctgac cgctctagag 1020 atagagcttt ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattt 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggctggt acaacgagtc 1260 gcgagtcggt gacggcaagc taatctctta aagccagtct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttagga gccagccgcc taaggtggga tagatgattg gggtgaagtc 1500 gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tccttt 1546 <210> 172 <211> 1547 <212> DNA <213> Streptococcus parasanguis <400> 172 taatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcctaat acatgcaagt 60 agaacgctga agcttggtgc ttgcaccgag cggaggagtt gcgaacgggt gagtaacgcg 120 taggtaacct gcctcttagc gggggataac tattggaaac gatagctaat accgcataaa 180 agtcgacatt gcatgatgtt gacttgaaag gtgcaactgc atcactaaga gatggacctg 240 cgttgtatta gctagttggt gaggtaacgg ctcaccaagg cgacgataca tagccgacct 300 gagagggtga tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca 360 gtagggaatc ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag 420 gttttcggat cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac 480 actgtgacgg taacttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata 540 cgtaggtccc gagcgttatc cggatttatt gggcgtaaag cgagcgcagg cggttagata 600 agtctgaagt taaaggctgt ggcttaacca tagtacgctt tggaaactgt ttaacttgag 660 tgcagaaggg gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa 720 caccggtggc gaaagcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg 780 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taggtgttgg 840 gtcctttccg ggactcagtg ccgcagctaa cgcattaagc actccgcctg gggagtacga 900 ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt 960 ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga 1020 gatagagctt tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt 1080 cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt 1140 tagttgggca ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca 1200 aatcatcatg ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt 1260 cgcgagtcgg tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg 1320 caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat 1380 acgttcccgg gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt 1440 cggtgaggta accttttagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt 1500 cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctccttt 1547 <210> 173 <211> 1545 <212> DNA <213> Streptococcus parasanguis <400> 173 aatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gcttggtgct tgcaccgagc ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaaccta cctcttagcg ggggataact attggaaacg atagctaata ccgcataaaa 180 gtcggcattg catgatgttg acttgaaagg tgcaaatgca tcactgagag atggacctgc 240 gttgtattag ctagttggtg aggtaacggc tcaccaaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg acggaagtct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagag aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt aacttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttatcc ggatttattg ggcgtaaagc gagcgcaggc ggttagataa 600 gtctgaagtt aaaggctgtg gcttaaccat agtacgcttt ggaaactgtt taacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttggg 840 tcctttccgg gactcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tccctctgac cgctctagag 1020 atagagcttt ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattt 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggctggt acaacgagtc 1260 gcgagtcggt gacggcaagc taatctctta aagccagtct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttagga gccagccgcc taaggtggga tagatgattg gggtgaagtc 1500 gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc tcctt 1545 <210> 174 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 174 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 175 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 175 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 176 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 176 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 177 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 177 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 178 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 178 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 179 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 179 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 180 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 180 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 181 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 181 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 182 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 182 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 183 <211> 1528 <212> DNA <213> Bacteroides_dorei <400> 183 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ctgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggcc agccttctga aaggaagatt aatccaggat 180 gggatcatga gttcacatgt ccgcatgatt aaaggtattt tccggtagac gatggggatg 240 cgttccatta gatagtaggc ggggtaacgg cccacctagt caacgatgga taggggttct 300 gagaggaagg tcccccacat tggaactgag acacggtcca aactcctacg ggaggcagca 360 gtgaggaata ttggtcaatg ggcgatggcc tgaaccagcc aagtagcgtg aaggatgact 420 gccctatggg ttgtaaactt cttttataaa ggaataaagt cgggtatgca tacccgtttg 480 catgtacttt atgaataagg atcggctaac tccgtgccag cagccgcggt aatacggagg 540 atccgagcgt tatccggatt tattgggttt aaagggagcg tagatggatg tttaagtcag 600 ttgtgaaagt ttgcggctca accgtaaaat tgcagttgat actggatgtc ttgagtgcag 660 ttgaggcagg cggaattcgt ggtgtagcgg tgaaatgctt agatatcacg aagaactccg 720 attgcgaagg cagcctgcta agctgcaact gacattgagg ctcgaaagtg tgggtatcaa 780 acaggattag ataccctggt agtccacacg gtaaacgatg aatactcgct gtttgcgata 840 tacggcaagc ggccaagcga aagcgttaag tattccacct ggggagtacg ccggcaacgg 900 tgaaactcaa aggaattgac gggggcccgc acaagcggag gaacatgtgg tttaattcga 960 tgatacgcga ggaaccttac ccgggcttaa attgcactcg aatgatccgg aaacggttca 1020 gctagcaata gcgagtgtga aggtgctgca tggttgtcgt cagctcgtgc cgtgaggtgt 1080 cggcttaagt gccataacga gcgcaaccct tgttgtcagt tactaacagg tgatgctgag 1140 gactctgaca agactgccat cgtaagatgt gaggaaggtg gggatgacgt caaatcagca 1200 cggcccttac gtccggggct acacacgtgt tacaatgggg ggtacagagg gccgctacca 1260 cgcgagtgga tgccaatccc taaaacccct ctcagttcgg actggagtct gcaacccgac 1320 tccacgaagc tggattcgct agtaatcgcg catcagccac ggcgcggtga atacgttccc 1380 gggccttgta cacaccgccc gtcaagccat gggagccggg ggtacctgaa gtgcgtaacc 1440 gcgaggatcg ccctagggta aaactggtga ctggggctaa gtcgtaacaa ggtagccgta 1500 ccggaaggtg cggctggaac acctcctt 1528 <210> 184 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 184 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 agcataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggctc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gttagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat cttcagttac taacaggtca tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 185 <211> 1302 <212> DNA <213> Bacteroides fragilis <400> 185 aaaggatggg gatgcgttcc attaggttgt tggtgaggta acggctcacc aagccttcga 60 tggatagggg ttctgagagg aaggtccccc acattggaac tgagacacgg tccaaactcc 120 tacgggaggc agcagtgagg aatattggtc aatgggcgct agcctgaacc agccaagtag 180 cgtgaaggat gaaggctcta tgggtcgtaa acttctttta tataagaata aagtgcagta 240 tgtatactgt tttgtatgta ttatatgaat aaggatcggc taactccgtg ccagcagccg 300 cggtaatacg gaggatccga gcgttatccg gatttattgg gtttaaaggg agcgtaggtg 360 gactggtaag tcagttgtga aagtttgcgg ctcaaccgta aaattgcagt tgatactgtc 420 agtcttgagt acagtagagg tgggcggaat tcgtggtgta gcggtgaaat gcttagatat 480 cacgaagaac tccgattgcg aaggcagctc actggactgc aactgacact gatgctcgaa 540 agtgtgggta tcaaacagga ttagataccc tggtagtcca cacagtaaac gatgaatact 600 cgctgtttgc gatatacagt aagcggccaa gcgaaagcat taagtattcc acctggggag 660 tacgccggca acggtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggaggaacat 720 gtggtttaat tcgatgatac gcgaggaacc ttacccgggc ttaaattgca gtggaatgat 780 gtggaaacat gtcagtgagc aatcaccgct gtgaaggtgc tgcatggttg tcgtcagctc 840 gtgccgtgag gtgtcggctt aagtgccata acgagcgcaa cccttatctt cagttactaa 900 caggttatgc tgaggactct ggagagactg ccgtcgtaag atgtgaggaa ggtggggatg 960 acgtcaaatc agcacggccc ttacgtccgg ggctacacac gtgttacaat ggggggtaca 1020 gaaggcagct agcgggtgac cgtatgctaa tcccaaaagc ctctctcagt tcggatcgaa 1080 gtctgcaacc cgacttcgtg aagctggatt cgctagtaat cgcgcatcag ccacggcgcg 1140 gtgaatacgt tcccgggcct tgtacacacc gcccgtcaag ccatgggagc cgggggtacc 1200 tgaagtacgt aaccgcaagg atcgtcctag ggtaaaactg gtgactgggg ctaagtcgta 1260 acaaggtagc cgtaccggaa ggtgcggctg gaacacctcc tt 1302 <210> 186 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 186 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 agtataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gttagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat cttcagttac taacaggtca tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 187 <211> 1331 <212> DNA <213> Bacteroides fragilis <400> 187 gcatggtttc attattaaag gattccggta aaggatgggg atgcgttcca ttaggttgtt 60 ggtgaggtaa cggctcacca agccttcgat ggataggggt tctgagagga aggtccccca 120 cattggaact gagacacggt ccaaactcct acgggaggca gcagtgagga atattggtca 180 atgggcgcta gcctgaacca gccaagtagc gtgaaggatg aaggctctat gggtcgtaaa 240 cttcttttat ataagaataa agtgcagtat gtatactgtt ttgtatgtat tatatgaata 300 aggatcggct aactccgtgc cagcagccgc ggtaatacgg aggatccgag cgttatccgg 360 atttattggg tttaaaggga gcgtaggtgg actggtaagt cagttgtgaa agtttgcggc 420 tcaaccgtaa aattgcagtt gatactgtca gtcttgagta cagtagaggt gggcggaatt 480 cgtggtgtag cggtgaaatg cttagatatc acgaagaact ccgattgcga aggcagctca 540 ctggactgca actgacactg atgctcgaaa gtgtgggtat caaacaggat tagataccct 600 ggtagtccac acagtaaacg atgaatactc gctgtttgcg atatacagta agcggccaag 660 cgaaagcatt aagtattcca cctggggagt acgccggcaa cggtgaaact caaaggaatt 720 gacgggggcc cgcacaagcg gaggaacatg tggtttaatt cgatgatacg cgaggaacct 780 tacccgggct taaattgcag tggaatgatg tggaaacatg tcagtgagca atcaccgctg 840 tgaaggtgct gcatggttgt cgtcagctcg tgccgtgagg tgtcggctta agtgccataa 900 cgagcgcaac ccttatcttt agttactaac aggttatgct gaggactctg gagagactgc 960 cgtcgtaaga tgtgaggaag gtggggatga cgtcaaatca gcacggccct tacgtccggg 1020 gctacacacg tgttacaatg gggggtacag aaggcagcta gcgggtgacc gtatgctaat 1080 cccaaaagcc tctctcagtt cggatcgaag tctgcaaccc gacttcgtga agctggattc 1140 gctagtaatc gcgcatcagc cacggcgcgg tgaatacgtt cccgggcctt gtacacaccg 1200 cccgtcaagc catgggagcc gggggtacct gaagtacgta accgcaagga tcgtcctagg 1260 gtaaaactgg tgactggggc taagtcgtaa caaggtagcc gtaccggaag gtgcggctgg 1320 aacacctcct t 1331 <210> 188 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 188 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 agtataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggctc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gctagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtta tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 189 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 189 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gctagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat cttcagttac taacaggtca tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 190 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 190 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggctc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gctagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat cttcagttac taacaggtca tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 191 <211> 1525 <212> DNA <213> Bacteroides fragilis <400> 191 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcatc aggaagaaag cttgctttct ttgctggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgcccttt actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcataatga ttccgcatgg tttcattatt aaaggattcc ggtaaaggat ggggatgcgt 240 tccattaggt tgttggtgag gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatgggc gctagcctga accagccaag tagcgtgaag gatgaaggct 420 ctatgggtcg taaacttctt ttatataaga ataaagtgca gtatgtatac tgttttgtat 480 gtattatatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gtggactggt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gtcagtcttg agtacagtag 660 aggtgggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag ctcactggac tgcaactgac actgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cattaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttaaatt gcagtggaat gatgtggaaa catgtcagtg 1020 agcaatcacc gctgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat cttcagttac taacaggtca tgctgaggac 1140 tctggagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctagcgggt 1260 gaccgtatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccacggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatggg agccgggggt acctgaagta cgtaaccgca 1440 aggatcgtcc tagggtaaaa ctggtgactg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 192 <211> 1202 <212> DNA <213> Bacteroides uniformis <400> 192 actgagacac ggtccaaact cctacgggag gcagcagtga ggaatattgg tcaatggacg 60 agagtctgaa ccagccaagt agcgtgaagg atgactgccc tatgggttgt aaacttcttt 120 tatacgggaa taaagtgagg cacgtgtgcc tttttgtatg taccgtatga ataaggatcg 180 gctaactccg tgccagcagc cgcggtaata cggaggatcc gagcgttatc cggatttatt 240 gggtttaaag ggagcgtagg cggacgctta agtcagttgt gaaagtttgc ggctcaaccg 300 taaaattgca gttgatactg ggtgtcttga gtacagtaga ggcaggcgga attcgtggtg 360 tagcggtgaa atgcttagat atcacgaaga actccgattg cgaaggcagc ttgctggact 420 gtaactgacg ctgatgctcg aaagtgtggg tatcaaacag gattagatac cctggtagtc 480 cacacagtaa acgatgaata ctcgctgttt gcgatataca gtaagcggcc aagcgaaagc 540 gttaagtatt ccacctgggg agtacgccgg caacggtgaa actcaaagga attgacgggg 600 gcccgcacaa gcggaggaac atgtggttta attcgatgat acgcgaggaa ccttacccgg 660 gcttgaattg caactgaatg atgtggagac atgtcagccg caaggcagtt gtgaaggtgc 720 tgcatggttg tcgtcagctc gtgccgtgag gtgtcggctt aagtgccata acgagcgcaa 780 cccttatcga tagttaccat caggttatgc tggggactct gtcgagactg ccgtcgtaag 840 atgtgaggaa ggtggggatg acgtcaaatc agcacggccc ttacgtccgg ggctacacac 900 gtgttacaat ggggggtaca gaaggcagct acacggcgac gtgatgctaa tcccgaaagc 960 ctctctcagt tcggattgga gtctgcaacc cgactccatg aagctggatt cgctagtaat 1020 cgcgcatcag ccacggcgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaag 1080 ccatgaaagc cgggggtacc tgaagtgcgt aaccgcaagg agcgccctag ggtaaaactg 1140 gtgattgggg ctaagtcgta acaaggtagc cgtaccggaa ggtgcggctg gaacacctcc 1200 tt 1202 <210> 193 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 193 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tggaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 194 <211> 1202 <212> DNA <213> Bacteroides uniformis <400> 194 actgagacac ggtccaaact cctacgggag gcagcagtga ggaatattgg tcaatggacg 60 agagtctgaa ccagccaagt agcgtgaagg atgactgccc tatgggttgt aaacttcttt 120 tatacgggaa taaagtgagg cacgtgtgcc tttttgtatg taccgtatga ataaggatcg 180 gctaactccg tgccagcagc cgcggtaata cggaggatcc gagcgttatc cggatttatt 240 gggtttaaag ggagcgtagg cggacgctta agtcagttgt gaaagtttgc ggctcaaccg 300 taaaattgca gttgatactg ggtgtcttga gtacagtaga ggcaggcgga attcgtggtg 360 tagcggtgaa atgcttagat atcacgaaga actccgattg cgaaggcagc ttgctggact 420 gtaactgacg ctgatgctcg aaagtgtggg tatcaaacag gattagatac cctggtagtc 480 cacacagtaa acgatgaata ctcgctgttt gcgatataca gtaagcggcc aagcgaaagc 540 gttaagtatt ccacctgggg agtacgccgg caacggtgaa actcaaagga attgacgggg 600 gcccgcacaa gcggaggaac atgtggttta attcgatgat acgcgaggaa ccttacccgg 660 gcttgaattg caactgaatg atgtggagac atgtcagccg caaggcagtt gtgaaggtgc 720 tgcatggttg tcgtcagctc gtgccgtgag gtgtcggctt aagtgccata acgagcgcaa 780 cccttatcga tagttaccat caggttatgc tggggactct gtcgagactg ccgtcgtaag 840 atgtgaggaa ggtggggatg acgtcaaatc agcacggccc ttacgtccgg ggctacacac 900 gtgttacaat ggggggtaca gaaggcagct acacggcgac gtgatgctaa tcccgaaagc 960 ctctctcagt tcggattgga gtctgcaacc cgactccatg aagctggatt cgctagtaat 1020 cgcgcatcag ccacggcgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaag 1080 ccatgaaagc cgggggtacc tgaagtgcgt aaccgcaagg agcgccctag ggtaaaactg 1140 gtgattgggg ctaagtcgta acaaggtagc cgtaccggaa ggtgcggctg gaacacctcc 1200 tt 1202 <210> 195 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 195 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 196 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 196 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tggaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 197 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 197 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 198 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 198 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 199 <211> 1051 <212> DNA <213> Bacteroides vulgatus <400> 199 tttgcatgta ctttatgaat aaggatcggc taactccgtg ccagcagccg cggtaatacg 60 gaggatccga gcgttatccg gatttattgg gtttaaaggg agcgtagatg gatgtttaag 120 tcagttgtga aagtttgcgg ctcaaccgta aaattgcagt tgatactgga tatcttgagt 180 gcagttgagg caggcggaat tcgtggtgta gcggtgaaat gcttagatat cacgaagaac 240 tccgattgcg aaggcagcct gctaagctgc aactgacatt gaggctcgaa agtgtgggta 300 tcaaacagga ttagataccc tggtagtcca cacggtaaac gatgaatact cgctgtttgc 360 gatatacggc aagcggccaa gcgaaagcgt taagtattcc acctggggag tacgccggca 420 acggtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggaggaacat gtggtttaat 480 tcgatgatac gcgaggaacc ttacccgggc ttaaattgca gatgaattac ggtgaaagcc 540 gtaagccgca aggcatctgt gaaggtgctg catggttgtc gtcagctcgt gccgtgaggt 600 gtcggcttaa gtgccataac gagcgcaacc cttgttgtca gttactaaca ggttctgctg 660 aggactctga caagactgcc atcgtaagat gtgaggaagg tggggatgac gtcaaatcag 720 cacggccctt acgtccgggg ctacacacgt gttacaatgg ggggtacaga gggccgctac 780 cacgcgagtg gatgccaatc ccaaaaacct ctctcagttc ggactggagt ctgcaacccg 840 actccacgaa gctggattcg ctagtaatcg cgcatcagcc acggcgcggt gaatacgttc 900 ccgggccttg tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtgcgtaa 960 ccgcgaggag cgccctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg 1020 taccggaagg tgcggctgga acacctcctt t 1051 <210> 200 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 200 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gttcacatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatggata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cggcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 201 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 201 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtaggcga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatgtata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 202 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 202 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgcaggcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatgcata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttcc gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggtcg ctaccacgcg 1260 agtggatgcc aatccccaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 203 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 203 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatggata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 204 <211> 1054 <212> DNA <213> Bacteroides vulgatus <400> 204 ccgtttgcat gtactttatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat 60 acggaggatc cgagcgttat ccggatttat tgggtttaaa gggagcgtag atggatgttt 120 aagtcagttg tgaaagtttg cggctcaacc gtaaaattgc agttgatact ggatatcttg 180 agtgcagttg aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag 240 aactccgatt gcgaaggcag cctgctaagc tgcaactgac attgaggctc gaaagtgtgg 300 gtatcaaaca ggattagata ccctggtagt ccacacggta aacgatgaat actcgctgtt 360 tgcgatatac agcaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg 420 gcaacggtga aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt 480 aattcgatga tacgcgagga accttacccg ggcttaaatt gcagatgaat tacggtgaaa 540 gccgtaagcc gcaaggcatc tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga 600 ggtgtcggct taagtgccat aacgagcgca acccttgttg tcagttacta acaggttctg 660 ctgaggactc tgacaagact gccatcgtaa gatgtgagga aggtggggat gacgtcaaat 720 cagcacggcc cttacgtccg gggctacaca cgtgttacaa tggggggtac agagggccgc 780 taccacgcga gtggatgcca atccccaaaa cctctctcag ttcggactgg agtctgcaac 840 ccgactccac gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg 900 ttcccgggcc ttgtacacac cgcccgtcaa gccatgggag ccgggggtac ctgaagtgcg 960 taaccgcgag gagcgcccta gggtaaaact ggtgactggg gctaagtcgt aacaaggtag 1020 ccgtaccgga aggtgcggct ggaacacctc cttt 1054 <210> 205 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 205 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 206 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 206 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 207 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 207 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccatatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtgaagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 208 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 208 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta agttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 209 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 209 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccatatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 210 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 210 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 211 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 211 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgaatgact catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 212 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 212 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgaatgact catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 213 <211> 1547 <212> DNA <213> Streptococcus salivarius <400> 213 aatgagagtt tgaccttcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa 60 gtagaacgct gaagagagga gcttgctctt cttggatgag ttgcgaacgg gtgagtaacg 120 cgtaggtaac ctgccttgta gcgggggata actattggaa acgatagcta ataccgcata 180 acaatgaatg actcatgtca tttatttgaa aggggcaatt gctccactac aagatggacc 240 tgcgttgtat tagctagtag gtgaggtaac ggctcaccta ggcgacgata catagccgac 300 ctgagagggt gatcggccac actgggactg agacacggcc cagactccta cgggaggcag 360 cagtagggaa tcttcggcaa tgggggcaac cctgaccgag caacgccgcg tgagtgaaga 420 aggttttcgg atcgtaaagc tctgttgtaa gtcaagaacg agtgtgagag tggaaagttc 480 acactgtgac ggtagcttac cagaaaggga cggctaacta cgtgccagca gccgcggtaa 540 tacgtaggtc ccgagcgttg tccggattta ttgggcgtaa agcgagcgca ggcggtttga 600 taagtctgaa gttaaaggct gtggctcaac catagttcgc tttggaaact gtcaaacttg 660 agtgcagaag gggagagtgg aattccatgt gtagcggtga aatgcgtaga tatatggagg 720 aacaccggtg gcgaaagcgg ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg 780 ggagcgaaca ggattagata ccctggtagt ccacgccgta aacgatgagt gctaggtgtt 840 ggatcctttc cgggattcag tgccgcagct aacgcattaa gcactccgcc tggggagtac 900 gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt ggagcatgtg 960 gtttaattcg aagcaacgcg aagaacctta ccaggtcttg acatcccgat gctatttcta 1020 gagatagaaa gttacttcgg tacatcggtg acaggtggtg catggttgtc gtcagctcgt 1080 gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctattgtta gttgccatca 1140 ttcagttggg cactctagcg agactgccgg taataaaccg gaggaaggtg gggatgacgt 1200 caaatcatca tgccccttat gacctgggct acacacgtgc tacaatggtt ggtacaacga 1260 gttgcgagtc ggtgacggca agctaatctc ttaaagccaa tctcagttcg gattgtaggc 1320 tgcaactcgc ctacatgaag tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga 1380 atacgttccc gggccttgta cacaccgccc gtcacaccac gagagtttgt aacacccgaa 1440 gtcggtgagg taaccttttg gagccagccg cctaaggtgg gatagatgat tggggtgaag 1500 tcgtaacaag gtagccgtat cggaaggtgc ggctggatca cctcctt 1547 <210> 214 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 214 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgaatgact catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 215 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 215 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgaatgact catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 216 <211> 1544 <212> DNA <213> Streptococcus salivarius <400> 216 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atgggtgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaacggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgagt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcaagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 217 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 217 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgtaag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaggccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 218 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 218 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttgcct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggccccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggatgccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgaaaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 219 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 219 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtgatgctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaagccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgaaaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 220 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 220 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagcg ggggtagcaa tacccgccgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggccccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaatgctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaggccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 221 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 221 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgtaag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaagccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 222 <211> 1531 <212> DNA <213> Clostridiaceae_bacterium_JC118 <400> 222 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtg aagatagctt gctattggaa cttagtggcg aacgggtgag taacacgtag 120 ataacctgcc tgtatgaccg ggataacagt tggaaacgac tgctaatacc ggataggcag 180 agaggaggca tctcttctct gttaaagttg ggacacaacg caaacagatg gatctgcggt 240 gcattagcta gttggtgagg taacggccca ccaaggcgat gatgcatagc cggcctgaga 300 gggcgaacgg ccacattggg actgagacac ggcccaaact cctacgggag gcagcagtag 360 ggaattttcg gcaatggggg aaaccctgac cgagcaatgc cgcgtgagtg aagacggcct 420 tcgggttgta aagctctgtt gtaagggaag aacggcatag agagggaatg ctctatgagt 480 gacggtacct taccagaaag ccacggctaa ctacgtgcca gcagccgcgg taatacgtag 540 gtggcaagcg ttatccggaa ttattgggcg taaagggtgc gtaggcggcg agataagtct 600 gaggtaaaag cccgtggctc aaccacggta agccttggaa actgtctggc tggagtgcag 660 gagaggacaa tggaattcca tgtgtagcgg taaaatgcgt agatatatgg aggaacacca 720 gtggcgaagg cggttgtctg gcctgtaact gacgctgaag cacgaaagcg tggggagcaa 780 ataggattag ataccctagt agtccacgcc gtaaacgatg agaactaagt gttggggaaa 840 ctcagtgctg cagttaacgc aataagttct ccgcctgggg agtatgcacg caagtgtgaa 900 actcaaagga attgacgggg gcccgcacaa gcggtggagt atgtggttta attcgacgca 960 acgcgaagaa ccttaccagg ccttgacatg gtatcaaagg ccctagagat agggagatag 1020 ttatggtaca cacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccttgtttct agttaccaac agtaagatgg ggactctaga 1140 gagactgccg gtgacaaacc ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tggcctgggc tacacacgta ctacaatggc gtctacaaag agcagcgagc aggtgactgt 1260 gagcgaatct cataaaggac gtctcagttc ggattgaagt ctgcaactcg acttcatgaa 1320 gtcggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttct cgggccttgt 1380 acacaccgcc cgtcaaacca tgggagttga taatacccga agccggtggc ctaaccattt 1440 atggagggag ccgtcgaagg taggatcgat gactggggtt aagtcgtaac aaggtatccc 1500 tacgggaacg tggggatgga tcacctcctt t 1531 <210> 223 <211> 981 <212> DNA <213> Anaerostipes_hadrus <400> 223 acctaccctg tacaggggga taacagtcag aaatgactgc taataccgca taagaccaca 60 gcaccgcatg gtgcaggggt aaaaactccg gtggtacagg atggacccgc gtctgattag 120 ctggttggtg aggtaacggc tcaccaaggc gacgatcagt agccggcttg agagagtgaa 180 cggccacatt gggactgaga cacggcccaa actcctacgg gaggcagcag tggggaatat 240 tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga gtgaagaagt atctcggtat 300 gtaaagctct atcagcaggg aagaaaatga cggtacctga ctaagaagcc ccggctaact 360 acgtgccagc agccgcggta atacgtaggg ggcaagcgtt atccggaatt actgggtgta 420 aagggtgcgt aggtggtatg gcaagtcaga agtgaaaacc cagggcttaa ctctgggact 480 gcttttgaaa ctgtcagact ggagtgcagg agaggtaagc ggaattccta gtgtagcggt 540 gaaatgcgta gatattagga ggaacatcag tggcgaaggc ggcttactgg actgaaactg 600 acactgaggc acgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgccg 660 taaacgatga atactaggtg tcggggccgt agaggcttcg gtgccgcagc caacgcagta 720 agtattccac ctggggagta cgttcgcaag aatgaaactc aaaggaattg acggggaccc 780 gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc gaagaacctt acctggtctt 840 gacatccttc tgaccggtcc ttaaccggac ctttccttcg ggacaggaga gacaggtggt 900 gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac 960 ccctatcttt agtagccagc a 981 <210> 224 <211> 1537 <212> DNA <213> Clostridium innocuum <400> 224 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagac tctaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacaga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcga ccacaaagag cagcgacttg 1260 gtgacaagaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 225 <211> 1537 <212> DNA <213> Clostridium innocuum <400> 225 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc ttcaggaagc ttgcttccaa aaagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacgga gcgcatgctc tgtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcga ccacaaagag cagcgacttg 1260 gtgacaagaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 226 <211> 1537 <212> DNA <213> Clostridium innocuum <400> 226 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc ttcaggaagc ttgcttccaa aaagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacgga gcgcatgctc tgtatattaa agcgcccttc aaggcgtgaa catggatgga 240 cctgcgacgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggagaaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcga ccacaaagag cagcgacttg 1260 gtgacaagaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 227 <211> 1537 <212> DNA <213> Clostridium innocuum <400> 227 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc ttcaggaagc ttgcttccaa aaagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacgga gcgcatgctc agtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcga ccacaaagag cagcgacttg 1260 gtgacaagaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 228 <211> 1537 <212> DNA <213> Clostridium innocuum <400> 228 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa aaagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gtccgggata actgctggaa acggtagcta aaaccggata 180 ggtatacgga gcgcatgctc tgtatattaa agcgcccatc aaggcgtgaa catggatgga 240 cctgcggcgc attagctagt tggtgaggta acggcccacc aaggcgatga tgcgtagccg 300 gcctgagagg gtaaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtaggg aattttcgtc aatgggggaa accctgaacg agcaatgccg cgtgagtgaa 420 gaaggtcttc ggatcgtaaa gctctgttgt aagtgaagaa cggctcatag aggaaatgct 480 atgggagtga cggtagctta ccagaaagcc acggctaact acgtgccagc agccgcggta 540 atacgtaggt ggcaagcgtt atccggaatc attgggcgta aagggtgcgt aggtggcgta 600 ctaagtctgt agtaaaaggc aatggctcaa ccattgtaag ctatggaaac tggtatgctg 660 gagtgcagaa gagggcgatg gaattccatg tgtagcggta aaatgcgtag atatatggag 720 gaacaccagt ggcgaaggcg gtcgcctggt ctgtaactga cactgaggca cgaaagcgtg 780 gggagcaaat aggattagat accctagtag tccacgccgt aaacgatgag aactaagtgt 840 tggaggaatt cagtgctgca gttaacgcaa taagttctcc gcctggggag tatgcacgca 900 agtgtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggtggagtat gtggtttaat 960 tcgaagcaac gcgaagaacc ttaccaggcc ttgacatgga aacaaatacc ctagagatag 1020 ggggataatt atggatcaca caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg 1080 ttgggttaag tcccgcaacg agcgcaaccc ttgtcgcatg ttaccagcat caagttgggg 1140 actcatgcga gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat 1200 gccccttatg gcctgggcta cacacgtact acaatggcga ccacaaagag cagcgacttg 1260 gtgacaagaa gcgaatctca taaaggtcgt ctcagttcgg attgaagtct gcaactcgac 1320 ttcatgaagt cggaatcgct agtaatcgca gatcagcatg ctgcggtgaa tacgttctcg 1380 ggccttgtac acaccgcccg tcaaaccatg ggagtcagta atacccgaag ccggtggcat 1440 aaccgtaagg agtgagccgt cgaaggtagg accgatgact ggggttaagt cgtaacaagg 1500 tatccctacg ggaacgtggg gatggatcac ctccttt 1537 <210> 229 <211> 1528 <212> DNA <213> Clostridium_hathewayi <400> 229 atgagagttc gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcgg tttcaatgaa gttttcggat ggaattgaaa ttgacttagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttacac tgggggataa cagttagaaa tgactgctaa 180 taccgcataa gcgcacaggg ccgcatggtc tggtgtgaaa aactccggtg gtgtaagatg 240 gacccgcgtc tgattaggta gttggtgggg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgg acaatgggcg aaagcctgat ccagcgacgc cgcgtgagtg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggttaagca agtctgaagt gaaagcccgg 600 ggctcaaccc cggtactgct ttggaaactg tttgacttga gtgcaggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggact gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg ggggacaacg tccttcggtg 840 ccgccgctaa cgcaataagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atcccattga aaacacttta accggtgtcc ctcttcggag 1020 caatggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatccttagt agccagcaca tgatggtggg cactctgggg 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gatttgggct acacacgtgc tacaatggcg taaacaaagg gaagcaaagg agcgatctgg 1260 agcaaacccc aaaaataacg tctcagttcg gattgcaggc tgcaactcgc ctgcatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagttggt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggcgg gactgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 230 <211> 927 <212> DNA <213> Clostridium_hathewayi <400> 230 atgagagttc gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcgg tttcaatgaa gttttcggat ggatttgaaa ttgacttagc ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttacac tgggggataa cagttagaaa tgactgctaa 180 taccgcataa gcgcacaggg ccgcatggtc tggtgtgaaa aactccggtg gtgtaagatg 240 gacccgcgtc tgattaggta gttggtgggg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgg acaatgggcg aaagcctgat ccagcgacgc cgcgtgagtg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggttaagca agtctgaagt gaaagcccgg 600 ggctcaaccc cggtactgct ttggaaactg tttgacttga gtgcaggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggact gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg ggggacaaag tccttcggtg 840 ccgccgctaa cgcaataagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcgg 927 <210> 231 <211> 1528 <212> DNA <213> Clostridium clostridiiforme <400> 231 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaagcaa ttaaaggaag ttttcggacg gaatttgatt gactgagtgg cggacgggtg 120 agtaacgcgt ggataacctg cctcacactg ggggataaca gttagaaatg actgctaata 180 ccgcataagc gcacagtacc gcatggtacg gtgtgaaaaa ctccggtggt gtgagatgga 240 tccgcgtctg attagccagt tggcggggta acggcccacc aaagcgacga tcagtagccg 300 acctgagagg gtgaccggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggcgaa agcctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcgaagcaag tctgaagtga aaacccaggg 600 ctcaaccctg ggactgcttt ggaaactgtt ttgctagagt gtcggagagg taagtggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggacgat aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgccgtaaac gatgaatgct aggtgttggg gggcaaagcc cttcggtgcc 840 gtcgcaaacg cagtaagcat tccacctggg gagtacgttc gcaagaatga aactcaaagg 900 aattgacggg gacccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga 960 accttaccaa gtcttgacat ccttttgacc ggcgtgtaac ggcgccttcc cttcggggca 1020 agagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc 1080 cgcaacgagc gcaaccctta tccttagtag ccagcaggta gagctgggca ctctagggag 1140 actgccaggg ataacctgga ggaaggcggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagacag tgatgtggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcga atcagaatgt cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgaccca actcgcaaga 1440 gagggagctg ccgaaggcgg ggcaggtaac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 232 <211> 1528 <212> DNA <213> Clostridium clostridiiforme <400> 232 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaagcaa ttaaaggaag ttttcggatg gaatttgatt gactgagtgg cggacgggtg 120 agtaacgcgt ggataacctg cctcacactg ggggataaca gttagaaatg actgctaata 180 ccgcataagc gcacagtgcc gcatggtacg gtgtgaaaaa ctccggtggt gtgagatgga 240 tccgcgtctg attagccagt tggcggggta acggcccacc aaagcgacga tcagtagccg 300 acctgagagg gtgaccggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggcgaa agcctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcgaagcaag tctgaagtga aaacccaggg 600 ctcaaccctg ggactgcttt ggaaactgtt ttgctagagt gtcggagagg taagtggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggacgat aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgccgtaaac gatgaatgct aggtgttggg gggcaaagcc cttcggtgcc 840 gtcgcaaacg cagtaagcat tccacctggg gagtacgttc gcaagaatga aactcaaagg 900 aattgacggg gacccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga 960 accttaccaa gtcttgacat cctcttgacc ggcgtgtaac ggcgccttcc cttcggggca 1020 agagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc 1080 cgcaacgagc gcaaccctta tccttagtag ccagcaggta gagctgggca ctctagggag 1140 actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagacag tgatgtggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcga atcagaatgt cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgaccca actcgcaaga 1440 gagggagctg ccgaaggcgg ggcaggtaac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 233 <211> 1528 <212> DNA <213> Clostridium clostridiiforme <400> 233 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaagcaa ttaaaggaag ttttcggatg gaatttgatt gactgagtgg cggacgggtg 120 agtaacgcgt ggataacctg cctcacactg ggggataaca gttagaaatg actgctaata 180 ccgcataagc gcacagtacc gcatggtacg gtgtgaaaaa ctccggtggt gtgagatgga 240 tccgcgtctg attagccagt tggcggggta acggcccacc aaagcgacga tcagtagccg 300 acctgagagg gtgaccggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggcgaa agcctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcgaagcaag tctgaagtga aaacccaggg 600 ctcaaccctg ggactgcttt ggaaactgtt ttgctagagt gtcggagagg taagtggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggacgat aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgccgtaaac gatgaatgct aggtgttggg gggcaaagcc cttcggtgcc 840 gtcgcaaacg cagtaagcat tccacctggg gagtacgttc gcaagaatga aactcaaagg 900 aattgacggg gacccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga 960 accttaccaa gtcttgacat cctcttggcc ggcgtgtaac ggcgccttcc cttcggggca 1020 agagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc 1080 cgcaacgagc gcaaccctta tccttagtag ccagcaggta gagctgggca ctctagggag 1140 actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagacag tgatgtggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcga atcagaatgt cgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgaccca actcgcaaga 1440 gagggagctg ccgaaggcgg ggcaggtaac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 234 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 234 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccgattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 235 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 235 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgacggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 236 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 236 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 237 <211> 1572 <212> DNA <213> Lactobacillus fermentum <400> 237 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gtccaattga ttgacggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgtttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taatggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgca aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc tt 1572 <210> 238 <211> 1572 <212> DNA <213> Lactobacillus fermentum <400> 238 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcgct gcattagctt gttggtgggg taatggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgtgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc tt 1572 <210> 239 <211> 1137 <212> DNA <213> Bacteroides thetaiotaomicron <400> 239 ctgaaccagc caagtagcgt gaaggatgac tgccctatgg gttgtaaact tcttttatat 60 gggaataaag ttttccacgt gtggaatttt gtatgtacca tatgaataag gatcggctaa 120 ctccgtgcca gcagccgcgg taatacggag gatccgagcg ttatccggat ttattgggtt 180 taaagggagc gtaggtggac agttaagtca gttgtgaaag tttgcggctc aaccgtaaaa 240 ttgcagttga tactggctgt cttgagtaca gtagaggtgg gcggaattcg tggtgtagcg 300 gtgaaatgct tagatatcac gaagaactcc gattgcgaag gcagctcact ggactgcaac 360 tgacactgat gctcgaaagt gtgggtatca aacaggatta gataccctgg tagtccacac 420 agtaaacgat gaatactcgc tgtttgcgat atacagtaag cggccaagcg aaagcattaa 480 gtattccacc tggggagtac gccggcaacg gtgaaactca aaggaattga cgggggcccg 540 cacaagcgga ggaacatgtg gtttaattcg atgatacgcg aggaacctta cccgggctta 600 aattgcattt gaatatattg gaaacagtat agccgtaagg caaatgtgaa ggtgctgcat 660 ggttgtcgtc agctcgtgcc gtgaggtgtc ggcttaagtg ccataacgag cgcaaccctt 720 atctttagtt actaacaggt catgctgagg actctagaga gactgccgtc gtaagatgtg 780 aggaaggtgg ggatgacgtc aaatcagcac ggcccttacg tccggggcta cacacgtgtt 840 acaatggggg gtacagaagg cagctacctg gtgacaggat gctaatccca aaagcctctc 900 tcagttcgga tcgaagtctg caacccgact tcgtgaagct ggattcgcta gtaatcgcgc 960 atcagccatg gcgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcaagccatg 1020 aaagccgggg gtacctgaag tacgtaaccg caaggagcgt cctagggtaa aactggtaat 1080 tggggctaag tcgtaacaag gtagccgtac cggaaggtgc ggctggaaca cctcctt 1137 <210> 240 <211> 1137 <212> DNA <213> Bacteroides thetaiotaomicron <400> 240 ctgaaccagc caagtagcgt gaaggatgac tgccctatgg gttgtaaact tcttttatat 60 gggaataaag ttttccacgt gtggaatttt gtatgtacca tatgaataag gatcggctaa 120 ctccgtgcca gcagccgcgg taatacggag gatccgagcg ttatccggat ttattgggtt 180 taaagggagc gtaggtggac agttaagtca gttgtgaaag tttgcggctc aaccgtaaaa 240 ttgcagttga tactggctgt cttgagtaca gtagaggtgg gcggaattcg tggtgtagcg 300 gtgaaatgct tagatatcac gaagaactcc gattgcgaag gcagctcact ggactgcaac 360 tgacactgat gctcgaaagt gtgggtatca aacaggatta gataccctgg tagtccacac 420 agtaaacgat gaatactcgc tgtttgcgat atacagtaag cggccaagcg aaagcattaa 480 gtattccacc tggggagtac gccggcaacg gtgaaactca aaggaattga cgggggcccg 540 cacaagcgga ggaacatgtg gtttaattcg atgatacgcg aggaacctta cccgggctta 600 aattgcattt gaatatattg gaaacagtat agccgtaagg caaatgtgaa ggtgctgcat 660 ggttgtcgtc agctcgtgcc gtgaggtgtc ggcttaagtg ccataacgag cgcaaccctt 720 atctttagtt actaacaggt catgctgagg actctagaga gactgccgtc gtaagatgtg 780 aggaaggtgg ggatgacgtc aaatcagcac ggcccttacg tccggggcta cacacgtgtt 840 acaatggggg gtacagaagg cagctacctg gtgacaggat gctaatccca aaagcctctc 900 tcagttcgga tcgaagtctg caacccgact tcgtgaagct ggattcgcta gtaatcgcgc 960 atcagccatg gcgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcaagccatg 1020 aaagccgggg gtacctgaag tacgtaaccg caaggagcgt cctagggtaa aactggtaat 1080 tggggctaag tcgtaacaag gtagccgtac cggaaggtgc ggctggaaca cctcctt 1137 <210> 241 <211> 1525 <212> DNA <213> Bacteroides thetaiotaomicron <400> 241 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atttcagttt gcttgcaaac tggagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactcgggg atagcctttc gaaagaaaga ttaatacccg 180 atagtataat tagaccgcat ggtcttatta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag gcagttggtg aggtaacggc tcaccaaacc ttcgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg acgagagtct gaaccagcca agtagcgtga aggatgactg 420 ccctatgggt tgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggacag ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgata ctggctgtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactgg actgcaactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcatttga atatattgga aacagtatag 1020 ccgtaaggca aatgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtca tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctacctggt 1260 gacaggatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 242 <211> 1525 <212> DNA <213> Bacteroides thetaiotaomicron <400> 242 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atttcagttt gcttgcaaac tggagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactcgggg atagcctttc gaaagaaaga ttaatacccg 180 atggtataat tagaccgcat ggtcttgtta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag gcagttggtg aggtaacggc tcaccaaacc ttcgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg gcgcaggcct gaaccagcca agtagcgtga aggatgactg 420 ccctatgggt tgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggacag ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgata ctggctgtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactgg actgcaactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcatttga atatattgga aacagtatag 1020 ccgtaaggca aatgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtca tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctacctggt 1260 gacaggatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 243 <211> 1531 <212> DNA <213> Sutterella_wadsworthensis <400> 243 taaagagttt gatcctggct cagattgaac gctggcggca tgctttacac atgcaagtcg 60 aacggcagcg cggggagctt gctccctggc ggcgagtggc gcacgggtga gtaatacatc 120 ggaacgtgtc ttctagtggg ggataactgc ccgaaagggc agctaatacc gcatgagacc 180 tgagggtgaa agcgggggat cgcaagacct cgcgctggaa gagcggccga tgtccgatta 240 gctagttggt gaggtaaagg ctcaccaagg cgacgatcgg tagctggtct gagaggacga 300 ccagccacac tgggactgag acacggccca gactcctacg ggaggcagca gtggggaatt 360 ttggacaatg ggggcaaccc tgatccagcc atgccgcgtg caggatgaag gtcttcggat 420 tgtaaactgc ttttgtcagg gacgaaaagg gatgcgataa caccgtattc cgctgacggt 480 acctgaagaa taagcaccgg ctaactacgt gccagcagcc gcggtaatac gtagggtgca 540 agcgttaatc ggaattactg ggcgtaaagc gtgcgcaggc ggttctgtaa gatagatgtg 600 aaatccccgg gctcaacctg ggaattgcat atatgactgc aggacttgag tttgtcagag 660 gagggtggaa ttccacgtgt agcagtgaaa tgcgtagata tgtggaagaa caccgatggc 720 gaaggcagcc ctctggggca tgactgacgc tcatgcacga aagcgtgggg agcaaacagg 780 attagatacc ctggtagtcc acgccctaaa cgatgtctac tagttgttgg ggacgatagt 840 ccttggtaac gcagctaacg cgtgaagtag accgcctggg gagtacggtc gcaagattaa 900 aactcaaagg aattgacggg gacccgcaca agcggtggat gatgtggatt aattcgatgc 960 aacgcgaaaa accttaccta gccttgacat gccaggaagg tctgagagat cagaccgtgc 1020 ccgcaaggga atctggacac aggtgctgca tggctgtcgt cagctcgtgt cgtgagatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tgtcattagt tgctacgaaa gggcactcta 1140 atgagactgc cggtgacaaa ccggaggaag gtggggatga cgtcaagtcc tcatggccct 1200 tatggctagg gcctcacacg tcatacaatg gtcggaacag agggaagcga agccgcgagg 1260 tgaagccaat cccagaaaac cgatcgtagt ccggattgca gtctgcaact cgactgcatg 1320 aagtcggaat cgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtg gggttcacca gaagacgttt gcccaaccga 1440 aaggaaggcg gcgtccacgg tgggcttcat gactggggtg aagtcgtaac aaggtagccg 1500 taccggaagg tgcggctgga tcacctcctt t 1531 <210> 244 <211> 921 <212> DNA <213> Sutterella_wadsworthensis <220> <221> misc_feature <222> (921) <223> n is a, c, g, or t <400> 244 taaagagttt gatcctggct cagattgaac gctggcggca tgctttacac atgcaagtcg 60 aacggcagcg cggggagctt gctccctggc ggcgagtggc gcacgggtga gtaatacatc 120 ggaacgtgtc ttctagtggg ggataactgc ccgaaagggc agctaatacc gcatgagacc 180 tgagggtgaa agcgggggat cgcaagacct cgcgctggaa gagcggccga tgtccgatta 240 gctagttggt gaggtaaagg ctcaccaagg cgacgatcgg tagctggtct gagaggacga 300 ccagccacac tgggactgag acacggccca gactcctacg ggaggcagca gtggggaatt 360 ttggacaatg ggggcaaccc tgatccagcc atgccgcgtg caggatgaag gtcttcggat 420 tgtaaactgc ttttgtcagg gacgaaaagg gatgcgataa caccgtattc cgctgacggt 480 acctgaagaa taagcaccgg ctaactacgt gccagcagcc gcggtaatac gtagggtgca 540 agcgttaatc ggaattactg ggcgtaaagc gtgcgcaggc ggttctgtaa gatagatgtg 600 aaatccccgg gctcaacctg ggaattgcat atatgactgc aggacttgag tttgtcagag 660 gagggtggaa ttccacgtgt agcagtgaaa tgcgtagata tgtggaagaa caccgatggc 720 gaaggcagcc ctctgggaca tgactgacgc tcatgcacga aagcgtgggg agcaaacagg 780 attagatacc ctggtagtcc acgccctaaa cgatgtctac tagttgttgg ggacgatagt 840 ccttggtaac gcagctaacg cgtgaagtag accgcctggg gagtacggtc gcaagattaa 900 aactcaaagg aattgacggg n 921 <210> 245 <211> 1531 <212> DNA <213> Sutterella_wadsworthensis <400> 245 taaagagttt gatcctggct cagattgaac gctggcggca tgctttacac atgcaagtcg 60 aacggcagcg cggggagctt gctccctggc ggcgagtggc gcacgggtga gtaatacatc 120 ggaacgtgtc ttctagtggg ggataactgt ccgaaagggc agctaatacc gcatgagacc 180 tgagggtgaa agcgggggat cgcaagacct cgcgctggaa gagcggccga tgtccgatta 240 gctagttggt gaggtaaagg ctcaccaagg cgacgatcgg tagctggtct gagaggacga 300 ccagccacac tgggactgag acacggccca gactcctacg ggaggcagca gtggggaatt 360 ttggacaatg ggggcaaccc tgatccagcc atgccgcgtg caggatgaag gtcttcggat 420 tgtaaactgc ttttgtcagg gacgaaaagg gatgcgataa caccgtattc cgctgacggt 480 acctgaagaa taagcaccgg ctaactacgt gccagcagcc gcggtaatac gtagggtgca 540 agcgttaatc ggaattactg ggcgtaaagc gtgcgcaggc ggttctgtaa gatagatgtg 600 aaatccccgg gctcaacctg ggaattgcat atatgactgc aggacttgag tttgtcagag 660 gagggtggaa ttccacgtgt agcagtgaaa tgcgtagata tgtggaagaa caccgatggc 720 gaaggcagcc ctctgggaca tgactgacgc tcatgcacga aagcgtgggg agcaaacagg 780 attagatacc ctggtagtcc acgccctaaa cgatgtctac tagttgttgg ggacgatagt 840 ccttggtaac gcagctaacg cgtgaagtag accgcctggg gagtacggtc gcaagattaa 900 aactcaaagg aattgacggg gacccgcaca agcggtggat gatgtggatt aattcgatgc 960 aacgcgaaaa cccttcccta gccttgacat gccaggaagg tctgagagat cagaccgtgc 1020 ccgcaaggga atctggacac aggtgctgca tggctgtcgt cagctcgtgt cgtgagatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tgtcattagt tgctacgaaa gggcactcta 1140 atgagactgc cggtgacaaa ccggaggaag gtggggatga cgtcaagtcc tcatggccct 1200 tatggctagg gcctcacacg tcatacaatg gtcggaacag agggaagcga agccgcgagg 1260 tgaagccaat cccagaaaac cgatcgtagt ccggattgca gtctgcaact cgactgcatg 1320 aagtcggaat cgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtg gggttcacca gaagacgttt gcccaaccga 1440 aaggaaggcg gcgtccacgg tgggcttcat gactggggtg aagtcgtaac aaggtagccg 1500 taccggaagg tgcggctgga tcacctcctt t 1531 <210> 246 <211> 1531 <212> DNA <213> Sutterella_wadsworthensis <400> 246 taaagagttt gatcctggct cagattgaac gctggcggca tgctttacac atgcaagtcg 60 aacggcagcg cggggagctt gctccctggc ggcgagtggc gcacgggtga gtaatacatc 120 ggaacgtgtc ttctagtggg ggataactgc ccgaaagggc agctaatacc gcatgagacc 180 tgagggtgaa agcgggggat cgcaagacct cgcgctggaa gagcggccga tgtccgatta 240 gctagttggt gaggtaaagg ctcaccaagg cgacgatcgg tagctggtct gagaggacga 300 ccagccacac tgggactgag acacggccca gactcctacg ggaggcagca gtggggaatt 360 ttggacaatg ggggcaaccc tgatccagcc atgccgcgtg caggatgaag gtcttcggat 420 tgtaaactgc ttttgtcagg gacgaaaagg gatgcgataa caccgtattc cgctgacggt 480 acctgaagaa taagcaccgg ctaactacgt gccagcagcc gcggtaatac gtagggtgca 540 agcgttaatc ggaattactg ggcgtaaagc gtgcgcaggc ggttctgtaa gatagatgtg 600 aaatccccgg gctcaacctg ggaattgcat atatgactgc aggacttgag tttgtcagag 660 gagggtggaa ttccacgtgt agcagtgaaa tgcgtagata tgtggaagaa caccgatggc 720 gaaggcagcc ctctgggaca tgactgacgc tcatgcacga aagcgtgggg agcaaacagg 780 attagatacc ctggtagtcc acgccctaaa cgatgtctac tagttgttgg ggacgatagt 840 ccttggtaac gcagctaacg cgtgaagtag accgcctggg gagtacggtc gcaagattaa 900 aactcaaagg aattgacggg gacccgcaca agcggtggat gatgtggatt aattcgatgc 960 aacgcgaaaa accttaccta gccttgacat gccaggaagg cctgagagat caggccgtgc 1020 ccgcaaggga atctggacac aggtgctgca tggctgtcgt cagctcgtgt cgtgagatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tgtcattagt tgctacgaaa gggcactcta 1140 atgagactgc cggtgacaaa ccggaggaag gtggggatga cgtcaagtcc tcatggccct 1200 tatggctagg gcctcacacg tcatacaatg gtcggaacag agggaagcga agccgcgagg 1260 tgaagccaat cccagaaaac cgatcgtagt ccggattgca gtctgcaact cgactgcatg 1320 aagtcggaat cgctagtaat cgcggatcag catgccgcgg tgaatacgtt cccgggtctt 1380 gtacacaccg cccgtcacac catgggagtg gggttcacca gaagacgttt gcccaaccga 1440 aaggaaggcg gcgtccacgg tgggcttcat gactggggtg aagtcgtaac aaggtagccg 1500 taccggaagg tgcggctgga tcacctcctt t 1531 <210> 247 <211> 1527 <212> DNA <213> Clostridium_sp_KLE_1755 <400> 247 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acggagttat gcagaggaag ttttcggatg gaatcggcgt aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacagcttc acatgaggca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatgacaag ccagatgtga aaacccaggg 600 ctcaaccctg ggactgcatt tggaactgcc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tcccaatgac gtgcccgtaa cggggcattc tcttcggagc 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt atccttagta gccagcaggt aaagctgggc actctaggga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgttga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag cctgtgacct aaccgtaagg 1440 aaggagcagt cgaaggcagg tctaataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 248 <211> 1527 <212> DNA <213> Clostridium symbiosum <400> 248 atgagagttt gatcctggct caggatgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgaagcga tttaacggaa gttttcggat ggaagttgaa ttgactgagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttgtac tgggggacaa cagttagaaa tgactgctaa 180 taccgcataa gcgcacagta ttgcatgata cagtgtgaaa aactccggtg gtacaagatg 240 gacccgcgtc tgattagcta gttggtaagg taacggctta ccaaggcgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcgacgc cgcgtgagtg 420 aagaagtatt tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtaaagca agtctgaagt gaaagcccgc 600 ggctcaactg cgggactgct ttggaaactg tttaactgga gtgtcggaga ggtaagtgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcgac 720 ttactggacg ataactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag ctcttcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aggtcttgac atcgatccga cgggggagta acgtcccctt cccttcgggg 1020 cggagaagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tattctaagt agccagcggt tcggccggga actcttggga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 atctgggcta cacacgtgct acaatggcgt aaacaaagag aagcaagacc gcgaggtgga 1260 gcaaatctca aaaataacgt ctcagttcgg actgcaggct gcaactcgcc tgcacgaagc 1320 tggaatcgct agtaatcgcg aatcagaatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgcaagg 1440 agggagctgc cgaaggcggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 249 <211> 1432 <212> DNA <213> Eubacterium ramulus <400> 249 gttctgtgac tgagtggcgg acgggtgagt aacgcgtgga taacctgcct cacacagggg 60 gataacagtt ggaaacgact gctaataccg cataagcgca cagcaccgca tggtgcagtg 120 tgaaaaactc cggtggtgtg agatggatcc gcgtctgatt agcttgttgg cggggtaacg 180 gcccaccaag gcgacgatca gtagccggcc tgagagggcg accggccaca ttgggactga 240 gacacggccc agactcctac gggaggcagc agtggggaat attgcacaat gggggaaacc 300 ctgatgcagc gacgccgcgt gagcgatgaa gtatttcggt atgtaaagct ctatcagcag 360 ggaagataat gacggtacct gactaagaag ctccggctaa atacgtgcca gcagccgcgg 420 taatacgtat ggagcaagcg ttatccggat ttactgggtg taaagggagc gtaggcggtc 480 ctgcaagtct gatgtgaaag gccggggctc aaccccggga ctgcattgga aactgtagga 540 ctagagtgtc ggaggggtaa gtggaattcc tagtgtagcg gtgaaatgcg tagatattag 600 gaggaacacc agtggcgaag gcggcttact ggacgactac tgacgctgag gctcgaaagc 660 gtggggagca aacaggatta gataccctgg tagtccacgc cgtaaacgat gaatactagg 720 tgttggcagg taagacctgt cggtgccgca gcaaacgcaa taagtattcc acctggggag 780 tacgttcgca agaatgaaac tcaaaggaat tgacggggac ccgcacaagc ggtggagcat 840 gtggtttaat tcgaagcaac gcgaagaacc ttaccaagtc ttgacatccc ggtgacagaa 900 catgtaatgt gttttccctt cggggcaccg gtgacaggtg gtgcatggtt gtcgtcagct 960 cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttatcc ccagtagcca 1020 gcatttcgga tgggcactct gtggagactg ccagggacaa cctggaggaa ggtggggatg 1080 acgtcaaatc atcatgcccc ttatgacttg ggctacacac gtgctacaat ggcgtaaaca 1140 aagggaagcg agaccgcgag gtggagcaaa tcccaaaaat aacgtcccag ttcggattgt 1200 agtctgcaac tcgactacat gaagctggaa tcgctagtaa tcgcagatca gaatgctgcg 1260 gtgaatacgt tcccgggtct tgtacacacc gcccgtcaca ccatgggagt cggaaatgcc 1320 cgaagccggt ggcctaaccg caaggaagga gccgtcgaag gcaggtctga taactggggt 1380 gaagtcgtaa caaggtagcc gtatcggaag gtgcggctgg atcacctcct tt 1432 <210> 250 <211> 1528 <212> DNA <213> Ruminococcus gnavus <400> 250 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca cttttgcgga tttcttcgga ttgaagcaat tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt accgtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtggg gtaacggcct accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggaaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 ctttctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccccctg accgctcttt aatcggagct ttccttcggg 1020 acaggggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat ttcggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gaccagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc cgcgaggggg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 251 <211> 1528 <212> DNA <213> Ruminococcus gnavus <400> 251 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca ccttgacgga tttcttcgga ttgaagcctt ggtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggaaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 ctttctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccctctg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat tttggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gatcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc cgcgaggggg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 252 <211> 1528 <212> DNA <213> Ruminococcus gnavus <400> 252 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca ccttgacgga tttcttcgga ttgaagcctt ggtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggaaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 ctttctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccccctg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat tttggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gatcagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc cgcgaggggg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 253 <211> 1242 <212> DNA <213> Ruminococcus gnavus <220> <221> misc_feature <222> (1) <223> n is a, c, g, or t <400> 253 ncgacgatca gtagccgacc tgagagggtg accggccaca ttgggactga gacacggccc 60 aaactcctac gggaggcagc agtggggaat attgcacaat gggggaaacc ctgatgcagc 120 gacgccgcgt gagcgatgaa gtatttcggt atgtaaagct ctatcagcag ggaagaaaat 180 gacggtacct gactaagaag ccccggctaa ctacgtgcca gcagccgcgg taatacgtag 240 ggggcaagcg ttatccggat ttactgggtg taaagggagc gtagacggca tggcaagcca 300 gatgtgaaag cccggggctc aaccccggga ctgcatttgg aactgtcagg ctagagtgtc 360 ggagaggaaa gcggaattcc tagtgtagcg gtgaaatgcg tagatattag gaggaacacc 420 agtggcgaag gcggctttct ggacgatgac tgacgttgag gctcgaaagc gtggggagca 480 aacaggatta gataccctgg tagtccacgc cgtaaacgat gaatactagg tgtcgggtgg 540 caaagccatt cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca 600 agaatgaaac tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat 660 tcgaagcaac gcgaagaacc ttacctggtc ttgacatccc tctgaccgct ctttaatcgg 720 aactttcctt cgggacagag gagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga 780 gatgttgggt taagtcccgc aacgagcgca acccctatct ttagtagcca gcattttgga 840 tgggcactct agagagactg ccagggataa cctggaggaa ggtggggatg acgtcaaatc 900 atcatgcccc ttatgaccag ggctacacac gtgctacaat ggcgtaaaca aagggaagcg 960 agcccgcgag ggggagcaaa tcccaaaaat aacgtctcag ttcggattgt agtctgcaac 1020 tcgactacat gaagctggaa tcgctagtaa tcgcgaatca gaatgtcgcg gtgaatacgt 1080 tcccgggtct tgtacacacc gcccgtcaca ccatgggagt cagtaacgcc cgaagtcagt 1140 gacccaaccg caaggaggga gctgccgaag gtgggaccga taactggggt gaagtcgtaa 1200 caaggtagcc gtatcggaag gtgcggctgg atcacctcct tt 1242 <210> 254 <211> 1528 <212> DNA <213> Ruminococcus gnavus <400> 254 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca ccttgacgga tttcttcgga ttgaagcctt ggtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattaggt agttggtggg gtaacggcct accaagccga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggaaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 ctttctggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccctctg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat ttcggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gaccagggct acacacgtgc tacaatggcg taaacaaagg gaagcgagcc cgcgaggggg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgcaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 255 <211> 1372 <212> DNA <213> Blautia_wexlerae <400> 255 tcagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgggaaa tatttcattg agacttcggt ggatttgatc tatttctagt ggcggacggg 120 tgagtaacgc gtgggtaacc tgccttatac agggggataa cagtcagaaa tggctgctaa 180 taccgcataa gcgcacagag ctgcatggct cagtgtgaaa aactccggtg gtataagatg 240 gacccgcgtt ggattagcta gttggtgggg taacggccca ccaaggcgac gatccatagc 300 cggcctgaga gggtgaacgg ccacattggg actgagacac ggcccagact cctacgggag 360 gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc cgcgtgaagg 420 aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgtaga cggtgtggca agtctgatgt gaaaggcatg 600 ggctcaacct gtggactgca ttggaaactg tcatacttga gtgccggagg ggtaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg cgaaggcggc 720 ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgtcg ggtggcagag ccattcggtg 840 ccgtcgcaaa cgcagtaagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atccgcctga ccgatcctta accggatctt tccttcggga 1020 caggcgagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcctcagt agccagcatt taaggtgggc actctgggga 1140 gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagatt gtgagatgga 1260 gcaaatccca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg gg 1372 <210> 256 <211> 1305 <212> DNA <213> Gemmiger_formicilis <400> 256 aaaggattta ttcgcttcag gatggactcg cgtccaatta gctagttggt gaggtaacgg 60 cccaccaagg cgacgattgg tagccggact gagaggttga acggccacat tgggactgag 120 acacggccca gactcctacg ggaggcagca gtgggggata ttgcacaatg ggggaaaccc 180 tgatgcagcg acgccgcgtg gaggaagaag gttttcggat tgtaaactcc tgtcgttagg 240 gacgataatg acggtaccta acaagaaagc accggctaac tacgtgccag cagccgcggt 300 aaaacgtagg gtgcaagcgt tgtccggaat tactgggtgt aaagggagcg caggcggacc 360 ggcaagttgg aagtgaaatc catgggctca acccgtgaat tgctttcaaa actgctggcc 420 ttgagtagtg cagaggtagg tggaattccc ggtgtagcgg tggaatgcgt agatatcggg 480 aggaacacca gtggcgaagg cgacctactg ggcaccaact gacgctgagg ctcgaaagca 540 tgggtagcaa acaggattag ataccctggt agtccatgcc gtaaacgatg attactaggt 600 gttggaggat tgaccccttc agtgccgcag ttaacacaat aagtaatcca cctggggagt 660 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagca gtggagtatg 720 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccga tgcatagtgc 780 agagatgcat gaagtccttc gggacatcga gacaggtggt gcatggttgt cgtcagctcg 840 tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccttattgcc agttactacg 900 caagaggact ctggcgagac tgccgttgac aaaacggagg aaggtgggga tgacgtcaaa 960 tcatcatgcc ctttatgacc tgggctacac acgtactaca atggcgttta acaaagagaa 1020 gcaagaccgc gaggtggagc aaaactcaga aacaacgtct cagttcagat tgcaggctgc 1080 aactcgcctg catgaagtcg gaattgctag taatcgcgga tcagcatgcc gcggtgaata 1140 cgttcccggg ccttgtacac accgcccgtc acaccatgag agccgggggg acccgaagtc 1200 ggtagtctaa ccgcaaggag gacgccgccg aaggtaaaac tggtgattgg ggtgaagtcg 1260 taacaaggta gccgtatcgg aaggtgcggc tggatcacct ccttt 1305 <210> 257 <211> 1518 <212> DNA <213> Eisenbergiella_massiliensis <400> 257 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acggagttat gcagaggaag ttttcggatg gaatcggcgt aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacagcttc acatgaggca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatgacaag ccagatgtga aaacccaggg 600 ctcaaccctg ggactgcatt tggaactgcc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tcccaatgac gtgtccgtaa cggggcattc tcttcggagc 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt atccttagta gccagcaggt aaagctgggc actctaggga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgttga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag cctgtgacct aaccgcaagg 1440 gaggagcagt cgaaggcagg tctaataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatg 1518 <210> 258 <211> 1511 <212> DNA <213> Ruminococcus_sp. <400> 258 ctaaagagtt tgatcctggc tcaggacgaa cgctggcggc gcgcctaaca catgcaagtc 60 gaacggagaa atgctgagct tgctttgcat ttcttagtgg cggacgggtg agtaacacgt 120 gagcaacctg cctttgtgag gggaataacg tctggaaacg gacgctaata ccgcataacg 180 tcaaggaacc gcatggtttt ttgaccaaag attttatcgc acaaagatgg gctcgcggct 240 gattagctag ttggcggggt aacggcccac caaggcgacg atcagtagcc ggactgagag 300 gttgatcggc cacattggga ctgagacacg gcccagactc ctacgggagg cagcagtggg 360 ggatattgca caatggggga aaccctgatg cagcgacgcc gcgtgaggga agacggtttt 420 cggattgtaa acctctgtct tcagggacga aatcaatgac ggtacctgag gaggaagcca 480 cggctaacta cgtgccagca gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta 540 ctgggtgtaa agggagcgta ggcgggaatg caagttgaat gtttaaacta tcggctcaac 600 tgataatcgc gttcaaaact gcatttcttg agtggagtag aggcaggcgg aattcctagt 660 gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg cctgctgggc 720 tctaactgac gctgaggctc gaaagcgtgg gtagcaaaca ggattagata ccctggtagt 780 ccacgccgta aacgatgatt actaggtgtg gggggactga ccccttccgt gccggagtta 840 acacaataag taatccacct ggggagtacg gtcgcaagac tgaaactcaa aggaattgac 900 gggggcccgc acaagcagtg gagtatgtgg tttaattcga agcaacgcga agaaccttac 960 caggtcttga catcgtgcgc ataccgtaga gatacgggaa gtccttcggg acgcatagac 1020 aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga 1080 gcgcaaccct tattattagt tgctacgcaa gagcactcta atgagactgc cgttgacaaa 1140 acggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg 1200 tactacaatg gcacttaaca gagggaagca agaccgcgag gtggagcaaa cccccaaaaa 1260 gtgtctcagt tcggattgca ggctgcaacc cgcctgtatg aagtcggaat tgctagtaat 1320 cgcggatcag catgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac 1380 catgagagcc ggtaacaccc gaagtcagta gcctaaccgc aaggagggcg ctgccgaagg 1440 tgggattggt gattagggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga 1500 tcacctcctt t 1511 <210> 259 <211> 1530 <212> DNA <213> Roseburia_faecis <400> 259 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacgaagcac tctatttgat tttcttcgga aatgaagatt ttgtgactga gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgcctcat acagggggat aacagttgga aacgactgct 180 aataccgcat aagcgcacag gattgcatga tccggtgtga aaaactccgg tggtatggga 240 tggacccgcg tctgattagc cagttggcag ggtaacggcc taccaaagcg acgatcagta 300 gccgacctga gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag 420 cgaagaagta tttcggtatg taaagctcta tcagcaggaa agaaaaatga cggtacctga 480 ctaagaagca ccggctaaat acgtgccagc agccgcggta atacgtatgg tgcaagcgtt 540 atccggattt actgggtgta aagggagcgc aggcggtgcg gcaagtctga tgtgaaagcc 600 cggggctcaa ccccggtact gcattggaaa ctgtcgtact agagtgtcgg aggggtaagt 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgataactg acgctgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga atactaggtg tcggggagca ttgctcttcg 840 gtgccgcagc aaacgcaata agtattccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt accaagtctt gacatcccga tgacagagta tgtaatgtac tttctcttcg 1020 gagcatcggt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccctgttctt agtagccagc ggttcggccg ggcactctag 1140 ggagactgcc agggataacc tggaggaagg cggggatgac gtcaaatcat catgcccctt 1200 atgacttggg ctacacacgt gctacaatgg cgtaaacaaa gggaagcgga gccgtgaggc 1260 cgagcaaatc tcaaaaataa cgtctcagtt cggactgtag tctgcaaccc gactacacga 1320 agctggaatc gctagtaatc gcagatcaga atgctgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagttg gaaatgcccg aagtcagtga cccaaccgca 1440 aggagggagc tgccgaaggc aggttcgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 260 <211> 1521 <212> DNA <213> Butyrivibrio_sp. <400> 260 ttgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacggacgga ttggagcttg ctccatgaag ttagtggcgg acgggtgagt aacgcgtggg 120 taacctgccc tatgcagggg gataacgttt ggaaacgaac gctaataccg cataacctag 180 ttggttcgca tgaaccgact agcaaagatt ttatcggcat aggatggacc cgcgttggat 240 tagctagttg gtgagataac agcccaccaa ggcaacgatc catagccggc ctgagagggt 300 gaacggccac actgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tgggcgcaag cctgatgcag cgacgccgcg tgaaggatga aggtcttcgg 420 atcgtaaact tctatcagca gggaagaaac catgacggta cctgactaag aagccccggc 480 taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg gaattactgg 540 gtgtaaaggg tgcgtaggcg gcgatttaag tcagatgtga aaactcaggg ctcaaccttg 600 agactgcatc tgaaactgag ttgctagagt gcaggagagg aaagcggaat tccgagtgta 660 gcggtgaaat gcgtagagat tcggaggaac accagtagcg aaggcggctt tctggactgt 720 aactgacgct gaggcacgaa agcgtgggga gcgaacagga ttagataccc tggtagtcca 780 cgccgtaaac gatgaatact aggtgtcggg gcttacgggt ctcggtgccg cagctaacgc 840 attaagtatt ccacctggga agtacgaccg caaggttgaa actcaaagga attgacgggg 900 acccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa ccttacctaa 960 acttgacatc cctttgaccg gtccttaatc ggatctttac tagcttgcta gtacaaaggt 1020 gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa 1080 cgagcgcaac ccctatcttt agtagccatc attcagttgg gcactctaga gagactgcca 1140 gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta tgtttagggc 1200 tacacacgtg ctacaatggg tgctacaaag ggaagcaaat ccgcgaggcc gagcaaatct 1260 caaaaaagca ctcccagttc ggattgtagt ctgcaactcg actacatgaa gttggaatcg 1320 ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt acacaccgcc 1380 cgtcacacca tgggagttgg gggggcccaa cgccagtgac ctaacccgca agggaaggag 1440 ctgtctaagg caaaaccaat gactggggtg aagtcgtaac aaggtagccg tatcggaagg 1500 tgcggctgga tcacctcctt t 1521 <210> 261 <211> 1529 <212> DNA <213> Blautia_sp_CAG_257 <400> 261 acagagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacggggat tattttgaca gagacttcgg ttgaagtcgt tataatccta gtggcggacg 120 ggtgagtaac gcgtgggtaa cctgcctcac actgggggat aacagtcaga aatgactgct 180 aataccgcat aagcgcacag agctgcatgg ctcagtgtga aaaactccgg tggtgtgaga 240 tggacccgcg ttggattagc cagttggcag ggtaacggcc taccaaagcg acgatccata 300 gccggcctga gagggtggac ggccacattg ggactgagac acggcccaga ctcctacggg 360 aggcagcagt ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgaa 420 ggaagaagta tctcggtatg taaacttcta tcagcaggga agaaaatgac ggtacctgac 480 taagaagccc cggctaacta cgtgccagca gccgcggtaa tacgtagggg gcaagcgtta 540 tccggattta ctgggtgtaa agggagcgta gacggagcag caagtctgat gtgaaaggcg 600 ggggctcaac ccccggactg cattggaaac tgttgatctt gagtaccgga gaggtaagcg 660 gaattcctag tgtagcggtg aaatgcgtag atattaggag gaacaccagt ggcgaaggcg 720 gcttactgga cggtaactga cgttgaggct cgaaagcgtg gggagcaaac aggattagat 780 accctggtag tccacgccgt aaacgatgaa tactaggtgt cgggtggcag agccattcgg 840 tgccgcagca aacgcagtaa gtattccacc tggggagtac gttcgcaaga atgaaactca 900 aaggaattga cggggacccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg 960 aagaacctta ccaagtcttg acatccctct gaccggtgag taacgtcacc tttccttcgg 1020 gacagaggag acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa 1080 gtcccgcaac gagcgcaacc cctatcctta gtagccagcg gtttggccgg gcactctgag 1140 gagactgcca gggataacct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200 tgatttgggc tacacacgtg ctacaatggc gtaaacaaag ggaagcgaga gtgtgagctt 1260 aagcaaatcc caaaaataac gtcccagttc ggactgcagt ctgcaactcg actgcacgaa 1320 gctggaatcg ctagtaatcg cggatcagaa tgccgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag taacgcccga agtcagtgac cgaaccgaaa 1440 ggacggagct gccgaaggcg ggacggatga ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 262 <211> 1210 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 262 gaacggccac attgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 60 tattgcgcaa tgggggaaac cctgacgcag caacgccgcg tgattgaaga aggccttcgg 120 gttgtaaaga tctttaattg gggacgaaaa atgacggtac ccaaagaata agctccggct 180 aactacgtgc cagcagccgc ggtaatacgt agggagcaag cgttatccgg atttactggg 240 tgtaaagggc gagtaggcgg gctggcaagt tgggagtgaa atcccggggc ttaaccccgg 300 aactgctttc aaaactgctg gtcttgagtg atggagaggc aggcggaatt ccgtgtgtag 360 cggtgaaatg cgtagatata cggaggaaca ccagtggcga aggcggcctg ctggacatta 420 actgacgctg aggagcgaaa gcgtggggag caaacaggat tagataccct ggtagtccac 480 gccgtaaacg atggatacta ggtgtgggag gtattgaccc cttccgtgcc ggagttaaca 540 caataagtat cccacctggg gagtacggcc gcaaggttga aactcaaagg aattgacggg 600 ggcccgcaca agcagtggag tatgtggttt aattcgaagc aacgcgaaga accttaccag 660 gtcttgacat ccctctgacc gccctagaga tagggtttcc cttcggggca gaggtgacag 720 gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc 780 gcaaccctta cggttagttg atacgcaaga tcactctagc cggactgccg ttgacaaaac 840 ggaggaaggt ggggacgacg tcaaatcatc atgcccctta tgacctgggc tacacacgta 900 ctacaatggc agtcatacag agggaagcaa aacagtgatg tggagcaaat ccctaaaagc 960 tgtcccagtt cagattgcag gctgcaactc gcctgcatga agtcggaatt gctagtaatc 1020 gcggatcagc atgccgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc 1080 atgagagccg gtaatacccg aagtccgtag cctaaccgca aggagggcgc ggccgaaggt 1140 aggactggta attagggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat 1200 cacctccttt 1210 <210> 263 <211> 1307 <212> DNA <213> Gemmiger_formicilis <400> 263 aaaaggattt attcgcttta ggatggactc gcgtccaatt agctagttgg tgaggtaacg 60 gcccaccaag gcgacgattg gtagccggac tgagaggttg aacggccaca ttgggactga 120 gacacggccc agactcctac gggaggcagc agtgggggat attgcacaat gggggaaacc 180 ctgatgcagc gacgccgcgt ggaggaagaa ggttttcgga ttgtaaactc ctgtcgttag 240 ggacgataat gacggtacct aacaagaaag caccggctaa ctacgtgcca gcagccgcgg 300 taaaacgtag ggtgcaagcg ttgtccggaa ttactgggtg taaagggagc gcaggcggga 360 agacaagttg gaagtgaaaa ccatgggctc aacccatgaa ttgctttcaa aactgttttt 420 cttgagtagt gcagaggtag atggaattcc cggtgtagcg gtggaatgcg tagatatcgg 480 gaggaacacc agtggcgaag gcggtctact gggcaccaac tgacgctgag gctcgaaagc 540 atgggtagca aacaggatta gataccctgg tagtccatgc cgtaaacgat gattactagg 600 tgttggggga ttgaccccct cagtgccgca gttaacacaa taagtaatcc acctggggag 660 tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc agtggagtat 720 gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccg atgcatagca 780 cagagatgtg tgaaatcctt cgggacatcg agacaggtgg tgcatggttg tcgtcagctc 840 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccttattgc cagttactac 900 gttaagagga ctctggcgag actgccgttg acaaaacgga ggaaggtggg gatgacgtca 960 aatcatcatg ccctttatga cctgggctac acacgtacta caatggcgtt aaacaaagag 1020 aagcaagacc gcgaggtgga gcaaaactca aaaacaacgt ctcagttcag attgcaggct 1080 gcaactcgcc tgcatgaagt cggaattgct agtaatcgcg gatcagcatg ccgcggtgaa 1140 tacgttcccg ggccttgtac acaccgcccg tcacaccatg agagccgggg ggacccgaag 1200 tcgatagtct aaccgcaagg aggacgtcgc cgaaggtaaa actggtgatt ggggtgaagt 1260 cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctccttt 1307 <210> 264 <211> 1253 <212> DNA <213> Intestinimonas_butyriciproducens <400> 264 ggctcaccaa ggcgacgatc agtagccgga ctgagaggtt ggccggccac attgggactg 60 agacacggcc cagactccta cgggaggcag cagtggggaa tattgggcaa tgggcgaaag 120 cctgacccag caacgccgcg tgaaggaaga aggccctcgg gttgtaaact tcttttgtca 180 gggacgaagc aagtgacggt acctgacgaa taagccacgg ctaactacgt gccagcagcc 240 gcggtaatac gtaggtggca agcgttatcc ggatttactg ggtgtaaagg gcgtgtaggc 300 gggagtgcaa gtcagatgtg aaaactatgg gctcaaccca tagcctgcat ttgaaactgt 360 acttcttgag tgatggagag gcaggcggaa ttccctgtgt agcggtgaaa tgcgtagata 420 tagggaggaa caccagtggc gaaggcggcc tgctggacat taactgacgc tgaggcgcga 480 aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatggatac 540 taggtgtggg gggtctgacc ccctccgtgc cgcagttaac acaataagta tcccacctgg 600 ggagtacgat cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga 660 gtatgtggtt taattcgaag caacgcgaag aaccttacca ggacttgaca tcctactaac 720 gaagcagaga tgcataaggt gcccttcggg gaaagtagag acaggtggtg catggttgtc 780 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cttattgtta 840 gttgctacgc aagagcactc tagcgagact gccgttgaca aaacggagga aggtggggac 900 gacgtcaaat catcatgccc cttatgtcct gggccacaca cgtactacaa tggcggtcaa 960 cagagggaag caaagccgcg aggtggagca aatccctaaa agccgtccca gttcggattg 1020 caggctgaaa ctcgcctgta tgaagtcgga atcgctagta atcgcggatc agcatgccgc 1080 ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accatgagag tcgggaacac 1140 ccgaagtccg tagcctaaca gcaatggggg cgcggccgaa ggtgggttcg ataattgggg 1200 tgaagtcgta acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc ttt 1253 <210> 265 <211> 1529 <212> DNA <213> Oscillospiraceae_bacterium_VE202_24 <400> 265 tatagagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacggagc acccttgact gaggtttcgg ccaaatgata ggaatgctta gtggcggact 120 ggtgagtaac gcgtgaggaa cctaccttcc agagggggac aacagttgga aacgactgct 180 aataccgcat gacgcatgac cggggcatcc cgggcatgtc aaagatttta tcgctggaag 240 atggcctcgc gtctgattag ctagatggtg gggtaacggc ccaccatggc gacgatcagt 300 agccggactg agaggttgac cggccacatt gggactgaga tacggcccag actcctacgg 360 gaggcagcag tggggaatat tgggcaatgg acgcaagtct gacccagcaa cgccgcgtga 420 aggaagaagg ctttcgggtt gtaaacttct tttgtcaggg aagagtagaa gacggtacct 480 gacgaataag ccacggctaa ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg 540 ttgtccggat ttactgggtg taaagggcgt gcagccgggc cggcaagtca gatgtgaaat 600 ctggaggctt aacctccaaa ctgcatttga aactgtaggt cttgagtacc ggagaggtta 660 tcggaattcc ttgtgtagcg gtgaaatgcg tagatataag gaagaacacc agtggcgaag 720 gcggataact ggacggcaac tgacggtgag gcgcgaaagc gtggggagca aacaggatta 780 gataccctgg tagtccacgc tgtaaacgat ggatactagg tgtgcgggga ctgaccccct 840 gcgtgccgca gttaacacaa taagtatccc acctggggag tacgatcgca aggttgaaac 900 tcaaaggaat tgacgggggc ccgcacaagc ggtggattat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccagggc ttgacatcct actaacgaag tagagataca tcaggtgccc 1020 ttcggggaaa gtagagacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg 1080 ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ctacgcaaga gcactctagc 1140 gagactgccg ttgacaaaac ggaggaaggt ggggacgacg tcaaatcatc atgcccctta 1200 tgtcctgggc tacacacgta atacaatggc ggtcaacaga gggaggcaaa gccgcgaggc 1260 agagcaaacc cccaaaagcc gtcccagttc ggatcgcagg ctgcaacccg cctgcgtgaa 1320 gtcggaatcg ctagtaatcg cggatcagca tgccgcggtg aatacgttcc cgggccttgt 1380 acacaccgcc cgtcacacca tgagagtcgg gaacacccga agtccgtagc ctaaccgcaa 1440 ggagggcgcg gccgaaggtg ggttcgataa ttggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 266 <211> 1420 <212> DNA <213> Clostridium_sp_CAG_91 <400> 266 tagtggcgga cgggtgagta acgcgtgggt aacctgcctt gtactggggg acaacagttg 60 gaaacgactg ctaataccgc ataagcgcac agcttcgcat gaagcagtgt gaaaaactcc 120 ggtggtacaa gatggacccg cgtctgatta gctggttggt gaggtaacgg cccaccaagg 180 cgacgatcag tagccggcct gagagggtga acggccacat tgggactgag acacggccca 240 aactcctacg ggaggcagca gtggggaata ttgcacaatg ggggaaaccc tgatgcagca 300 acgccgcgtg agtgaagaag tatttcggta tgtaaagctc tatcagcagg aaagaaaatg 360 acggtacctg actaagaagc cccggctaac tacgtgccag cagccgcggt aatacgtagg 420 gggcaagcgt tatccggatt tactgggtgt aaagggagcg tagacggttt tgcaagtctg 480 aagtgaaagc ccggggctta accccgggac tgctttggaa actgtagaac tagagtgcag 540 gagaggtaag tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca 600 gtggcgaagg cggcttactg gactgtaact gacgttgagg ctcgaaagcg tggggagcaa 660 acaggattag ataccctggt agtccacgcc gtaaacgatg attactaggt gttggtgggt 720 acgacccatc ggtgccgcag caaacgcaat aagtaatcca cctggggagt acgttcgcaa 780 gaatgaaact caaaggaatt gacggggacc cgcacaagcg gtggagcatg tggtttaatt 840 cgaagcaacg cgaagaacct tacctggtct tgacatccct atgaataacg ggcaatgccg 900 ttagtacttc ggtacatagg agacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag 960 atgttgggtt aagtcccgca acgagcgcaa cccttatctt tagtagccag cagtaagatg 1020 ggcactctag agagactgcc ggggataacc cggaggaagg tggggatgac gtcaaatcat 1080 catgcccctt atgaccaggg ctacacacgt gctacaatgg cgtaaacaaa gagaagcgaa 1140 gtcgtgaggc agagcgaatc tcaaaaataa cgtctcagtt cggattgtag tctgcaactc 1200 gactacatga agctggaatc gctagtaatc gcagatcaga atgctgcggt gaatacgttc 1260 ccgggtcttg tacacaccgc ccgtcacacc atgggagtcg gaaatgcccg aagtcggtga 1320 cctaaccgca aggaaggagc cgccgaaggc aggtctgata actggggtga agtcgtaaca 1380 aggtagccgt atcggaaggt gcggctggat cacctccttt 1420 <210> 267 <211> 1177 <212> DNA <213> Ruminococcus obeum <400> 267 cctacgggag gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc 60 cgcgtgaagg aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg 120 tacctgacta agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc 180 aagcgttatc cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt 240 gaaaggcggg ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga 300 ggtaagcgga attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg 360 cgaaggcggc ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag 420 gattagatac cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag 480 ctcttcggtg ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat 540 gaaactcaaa ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa 600 gcaacgcgaa gaaccttacc aagtcttgac atccctctga ccgactctta accgagtctt 660 tccttcggga cagaggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt 720 tgggttaagt cccgcaacga gcgcaacccc tatccccagt agccagcggt tcggccgggc 780 actctgagga gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat 840 gccccttatg atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcaagcct 900 gcgaaggtaa gcaaatccca aaaataacgt cccagttcgg actgcagtct gcaactcgac 960 tgcacgaagc tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg 1020 ggtcttgtac acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct 1080 aaccgcaagg gaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg 1140 tagccgtatc ggaaggtgcg gctggatcac ctccttt 1177 <210> 268 <211> 1526 <212> DNA <213> Blautia_sp. <400> 268 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcaa tttaagtgaa gttttcggat ggatcttaga ttgactgagc ggcggacggg 120 tgagtaacgc gtggataacc tgcctcacac agggggataa cagttagaaa tgactgctaa 180 taccgcataa gcgcacggta ccgcatggta cagtgtgaaa aactccggtg gtgtgagatg 240 gatccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcaacgc cgcgtgagtg 420 aagaagtatc tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgcaga cggcactgca agtctgaagt gaaagcccgg 600 ggctcaaccc cgggactgct ttggaaactg tagagctaga gtgctggaga ggcaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggaaga acaccagtgg cgaaggcggc 720 ttgctggaca gtaactgacg ttcaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gtgggcaaag cccatcggtg 840 ccgccgcaaa cgcaataagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atcgtgatga ccggaactta accgttcctt cccttcgggg 1020 catcatagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcctcagt agccagcagt aagatgggca ctctggggag 1140 actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagaggg tgacctggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcag atcagaatgc tgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgactca accgcaagga 1440 gagagctgcc gaaggcgggg caggtaactg gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 269 <211> 1526 <212> DNA <213> Blautia_sp. <400> 269 atgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 agcgaagcaa tttaagtgaa gttttcggat ggatcttaga ttgactgagc ggcggacggg 120 tgagtaacgc gtggataacc tgcctcacac agggggataa cagttagaaa tgactgctaa 180 taccgcataa gcgcacggta ccgcatggta cagtgtgaaa aactccggtg gtgtgagatg 240 gatccgcgtc tgattaggta gttggtgagg taacggccca ccaagccgac gatcagtagc 300 cgacctgaga gggtgaccgg ccacattggg actgagacac ggcccaaact cctacgggag 360 gcagcagtgg ggaatattgc acaatgggcg aaagcctgat gcagcaacgc cgcgtgagtg 420 aagaagtatc tcggtatgta aagctctatc agcagggaag aaaatgacgg tacctgacta 480 agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc aagcgttatc 540 cggatttact gggtgtaaag ggagcgcaga cggcactgca agtctgaagt gaaagcccgg 600 ggctcaaccc cgggactgct ttggaaactg tagagctaga gtgctggaga ggcaagcgga 660 attcctagtg tagcggtgaa atgcgtagat attaggaaga acaccagtgg cgaaggcggc 720 ttgctggaca gtaactgacg ttcaggctcg aaagcgtggg gagcaaacag gattagatac 780 cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gtgggcaaag cccatcggtg 840 ccgccgcaaa cgcaataagt attccacctg gggagtacgt tcgcaagaat gaaactcaaa 900 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa 960 gaaccttacc aagtcttgac atcgtgatga ccggaactta accgttcctt cccttcgggg 1020 catcatagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaaccct tatcctcagt agccagcagt aagatgggca ctctgtggag 1140 actgccaggg ataacctgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga 1200 tttgggctac acacgtgcta caatggcgta aacaaaggga agcaagaggg tgacctggag 1260 caaatcccaa aaataacgtc ccagttcgga ctgtagtctg caacccgact acacgaagct 1320 ggaatcgcta gtaatcgcag atcagaatgc tgcggtgaat acgttcccgg gtcttgtaca 1380 caccgcccgt cacaccatgg gagtcagcaa cgcccgaagt cagtgactca accgcaagga 1440 gagagctgcc gaaggcgggg caggtaactg gggtgaagtc gtaacaaggt agccgtatcg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 270 <211> 1530 <212> DNA <213> Lachnospira pectinoschiza <400> 270 ttatgagagt ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgaagc atttgcgaca gatttcttcg gattgaagtt gcttatgact gagtggcgga 120 cgggtgagta acgcgtgggt aacctgcctc acacaggggg atagcagttg gaaacggctg 180 ataataccgc ataagcgcac agtaccgcat ggtacagtgt gaaaaactcc ggtggtgtga 240 gatggacccg cgtctgatta gcttgttggc agggtaacgg cctaccaagg caacgatcag 300 tagccgacct gagagggtga ccggccacat tgggactgag acacggccca gactcctacg 360 ggaggcagca gtggggaata ttgcacaatg gaggaaactc tgatgcagcg acgccgcgtg 420 agtgaagaag taattcgtta tgtaaagctc tatcagcagg gaagatagtg acggtacctg 480 actaagaagc tccggctaaa tacgtgccag cagccgcggt aatacgtatg gagcaagcgt 540 tatccggatt tactgggtgt aaagggagtg taggtggcat cacaagtcag aagtgaaagc 600 ccggggctca accccgggac tgcttttgaa actgtggagc tggagtgcag gagaggcaag 660 tggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggcttgctg gactgtaact gacactgagg ctcgaaagcg tggggagcaa acaggattag 780 ataccctggt agtccacgcc gtaaacgatg aatactaggt gtcggggctc ataagagctt 840 cggtgccgca gcaaacgcaa taagtattcc acctggggag tacgttcgca agaatgaaac 900 tcaaaggaat tgacggggac ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac 960 gcgaagaacc ttaccaagtc ttgacatcct cttgcccggt cagtaatgtg accttttctt 1020 cggaacaaga gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctattc ttagtagcca gcatttaagg tgggcactct 1140 aggaagactg ccagggataa cctggaggaa ggtggggatg acgtcaaatc atcatgcccc 1200 ttatgacttg ggctacacac gtgctacaat ggcgtaaaca aagtgaagcg agagtgtgag 1260 cttaagcaaa tcacaaaaat aacgtctcag ttcggattgt agtctgcaac tcgactacat 1320 gaagctggaa tcgctagtaa tcgcgaatca gaatgtcgcg gtgaatacgt tcccgggtct 1380 tgtacacacc gcccgtcaca ccatgggagt cggaaatgcc cgaagtcggt gacctaacga 1440 aagaaggagc cgccgaaggc aggtctgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 271 <211> 1226 <212> DNA <213> Lactonifactor_longoviformis <400> 271 ctgagagggt gaccggccac attgggactg agacacggcc caaactccta cgggaggcag 60 cagtggggaa tattgcacaa tgggggaaac cctgatgcag cgacgccgcg tgaaggaaga 120 agtatttcgg tatgtaaact tctatcagca gggaagaaaa tgacggtacc tgactaagaa 180 gccccggcta attacgtgcc agcagccgcg gtaatacgta aggggcaagc gttatccgga 240 tttactgggt gtaaagggag cgtagacggc agtgcaagtc tgatgtgaaa gcccggggct 300 caaccccggg actgcattgg aaactgtgca gctagagtgt cggagaggta agtggaattc 360 ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagtggcgaa ggcggcttac 420 tggacgataa ctgacgttga ggctcgaaag cgtggggagc aaacaggatt agataccctg 480 gtagtccacg ccgtaaacga tgaatactag gtgtcgggcg ccaaaggcgt tcggtgccgc 540 agcaaacgca ataagtattc cacctgggga gtacgttcgc aagaatgaaa ctcaaaggaa 600 ttgacgggga cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac 660 cttaccaagt cttgacatct gcctgaccgg tccgtaacag gacccttcct tcgggacagg 720 caagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg 780 caacgagcgc aacccttatc cttagtagcc agcaggtaga gctgggcact ctagggagac 840 tgccagggac aacctggagg aaggtgggga tgacgtcaaa tcatcatgcc ccttatgatt 900 tgggctacac acgtgctaca atggcgtaaa caaagggagg cgaaggggtg acctggagca 960 aatcccaaaa ataacgtctc agttcggatt gtagtctgca actcgactac atgaagctgg 1020 aatcgctagt aatcgcgaat cagaatgtcg cggtgaatac gttcccgggt cttgtacaca 1080 ccgcccgtca caccatggga gtcggatatg cccgaagccg gtgaccgaac ccgaaaggga 1140 aggagccgtc gaaggtggag ccgataactg gggtgaagtc gtaacaaggt agccgtatcg 1200 gaaggtgcgg ctggatcacc tccttt 1226 <210> 272 <211> 1530 <212> DNA <213> Eubacterium contortum <400> 272 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg ctttacttag atttcttcgg attgaagagt tttgcgactg agcggcggac 120 gggtgagtaa cgcgtgggta acctgcctca tacaggggga taacagttag aaatgactgc 180 taataccgca taagaccaca gtaccgcatg gtaccgtggg aaaaactccg gtggtatgag 240 atggacccgc gtctgattag ctagttggta aggtaacggc ttaccaaggc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaaaatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggttat gtaagtctga tgtgaaaacc 600 cggggctcaa ccccgggact gcattggaaa ctatgtaact agagtgtcgg agaggtaagt 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatgc atactaggtg tcgggtggca aagccattcg 840 gtgccgcagc aaacgcaata agtatgccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgctctt gacatccccc tgaccggcgc gtaatggtgc ctttccttcg 1020 ggacagggga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccttatcttt agtagccagc ggttcggccg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgagcaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa gccgcgaggt 1260 ggagcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagttg gtaacgcccg aagtcagtga cccaaccgta 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 273 <211> 1530 <212> DNA <213> Eubacterium contortum <400> 273 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg ctttacttag atttcttcgg attgaagagt tttgcgactg agcggcggac 120 gggtgagtaa cgcgtgggta acctgcctca tacaggggga caacagttag aaatgactgc 180 taataccgca taagaccacg gtaccgcatg gtacagtggg aaaaactccg gtggtatgag 240 atggacccgc gtctgattag ctagttggta aggtaacggc ttaccaaggc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaaaatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggttat gtaagtctga tgtgaaaacc 600 cggggctcaa ccccgggact gcattggaaa ctatgtaact agagtgtcgg agaggtaagt 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatgc atactaggtg tcgggtggca aagccattcg 840 gtgccgcagc aaacgcaata agtatgccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgctctt gacatccccc tgaccggcgc gtaatggtgc ctttccttcg 1020 ggacagggga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccttatcttt agtagccagc ggttcggccg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgagcaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa gccgcgaggt 1260 ggagcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagttg gtaacgcccg aagtcagtga cccaaccgta 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 274 <211> 1530 <212> DNA <213> Eubacterium contortum <400> 274 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg ctttacttag atttcttcgg attgaagagt tttgcgactg agcggcggac 120 gggtgagtaa cgcgtgggta acctgcctca tacaggggga taacagttag aaatgactgc 180 taataccgca taagaccacg gtaccgcatg gtacagtggg aaaaactccg gtggtatgag 240 atggacccgc gtctgattag ctagttggta aggtaacggc ttaccaaggc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaaaatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggttat gtaagtctga tgtgaaaacc 600 cggggctcaa ccccgggact gcattggaaa ctatgtaact agagtgtcgg agaggtaagt 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatgc atactaggtg tcgggtggca aagccattcg 840 gtgccgcagc aaacgcaata agtatgccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgctctt gacatccccc tgaccggcgc gtaatggtgc ctttccttcg 1020 ggacagggga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccttatcttt agtagccagc ggttcggccg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgagcaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa gccgcgaggt 1260 ggagcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagttg gtaacgcccg aagtcagtga cccaaccgta 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 275 <211> 1530 <212> DNA <213> Eubacterium contortum <400> 275 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagca ctttacttag atttcttcgg aatgaagagt gttgtgactg agcggcggac 120 gggtgagtaa cgcgtgggta acctgcctca tacaggggga taacagttag aaatgactgc 180 taataccgca taagaccacg gtaccgcatg gtacagtggg aaaaactccg gtggtatgag 240 atggacccgc gtctgattag ctagttggta aggtaacggc ttaccaaggc gacgatcagt 300 agccgacctg agagggtgac cggccacatt gggactgaga cacggcccaa actcctacgg 360 gaggcagcag tggggaatat tgcacaatgg gggaaaccct gatgcagcga cgccgcgtga 420 aggatgaagt atttcggtat gtaaacttct atcagcaggg aagaaaatga cggtacctga 480 ctaagaagcc ccggctaact acgtgccagc agccgcggta atacgtaggg ggcaagcgtt 540 atccggattt actgggtgta aagggagcgt agacggttat gtaagtctga tgtgaaaacc 600 cggggctcaa ccccgggact gcattggaaa ctatgtaact agagtgtcgg agaggtaagt 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgatgactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatgc atactaggtg tcgggtggca aagccattcg 840 gtgccgcagc aaacgcaata agtatgccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc 960 gaagaacctt acctgctctt gacatccccc tgaccggcgc gtaatggtgc ctttccttcg 1020 ggacagggga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080 agtcccgcaa cgagcgcaac ccttatcttt agtagccagc ggttcggccg ggcactctag 1140 agagactgcc agggataacc tggaggaagg tggggatgac gtcaaatcat catgcccctt 1200 atgagcaggg ctacacacgt gctacaatgg cgtaaacaaa gggaggcgaa gccgcgaggt 1260 ggagcaaatc ccaaaaataa cgtctcagtt cggattgtag tctgcaactc gactacatga 1320 agctggaatc gctagtaatc gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg 1380 tacacaccgc ccgtcacacc atgggagttg gtaacgcccg aagtcagtga cccaaccgta 1440 aggagggagc tgccgaaggt gggaccgata actggggtga agtcgtaaca aggtagccgt 1500 atcggaaggt gcggctggat cacctccttt 1530 <210> 276 <211> 884 <212> DNA <213> Eisenbergiella_tayi <400> 276 ggagaggtaa gcggaattcc tagtgtagcg gtgaaatgcg tagatattag gaggaacacc 60 agtggcgaag gcggcttact ggactgtaac tgacgttgag gctcgaaagc gtggggagca 120 aacaggatta gataccctgg tagtccacgc ggtaaacgat gattgctagg tgtaggtggg 180 tatggaccca tcggtgccgc agctaacgca ataagcaatc cacctgggga gtacgttcgc 240 aagaatgaaa ctcaaaggaa ttgacgggga cccgcacaag cggtggagca tgtggtttaa 300 ttcgaagcaa cgcgaagaac cttaccaagt cttgacatcc ccctgaatat ctcgtaaaag 360 ggataggcct tcgggacagg ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg 420 agatgttggg ttaagtcccg caacgagcgc aacccttatt cttagtagcc agcaggtaaa 480 gctgggcact ctaaggagac tgccggggat aacccggagg aaggcgggga tgacgtcaaa 540 tcatcatgcc ccttatgatt tgggctacac acgtgctaca atggcgtaaa caaagggaag 600 cgagacagtg atgtggagca aatcccagaa ataacgtctc agttcggatt gtagtctgca 660 actcgactac atgaagctgg aatcgctagt aatcgcgaat cagcatgtcg cggtgaatac 720 gttcccgggt cttgtacaca ccgcccgtca caccatggga gttggaaatg cccgaagtct 780 gtgacctaac cgaaagggag gagcagccga aggcaggtct gataactggg gtgaagtcgt 840 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc cttt 884 <210> 277 <211> 1528 <212> DNA <213> Ruminococcus_gnavus_sp <400> 277 aacgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgaagcg cttttgcgga tttcttcgga ttgaagcaac tgtgactgag cggcggacgg 120 gtgagtaacg cgtgggtaac ctgcctcata cagggggata acagttggaa acggctgcta 180 ataccgcata agcgcacagt accgcatggt accgtgtgaa aaactccggt ggtatgagat 240 ggacccgcgt ctgattagct agttggtggg gtaacggcct accaaggcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggg gaaaccctga tgcagcgacg ccgcgtgagc 420 gatgaagtat ttcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagccagatg tgaaagcccg 600 gggctcaacc ccgggactgc atttggaact gtcaggctag agtgtcggag aggtaagcgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac gatgactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat actaggtgtc gggtggcaaa gccattcggt 840 gccgcagcaa acgcaataag tattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac ctggtcttga catccctatg accgctcttt aatcggagct ttccttcggg 1020 acagaggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ctatctttag tagccagcat tttggatggg cactctagag 1140 agactgccag ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat 1200 gaccagggct acacacgtgc tacaatggcg taaacaaagg gaagcgaacc tgcgaggggg 1260 agcaaatccc aaaaataacg tctcagttcg gattgtagtc tgcaactcga ctacatgaag 1320 ctggaatcgc tagtaatcgc gaatcagaat gtcgcggtga atacgttccc gggtcttgta 1380 cacaccgccc gtcacaccat gggagtcagt aacgcccgaa gtcagtgacc caaccgtaag 1440 gagggagctg ccgaaggtgg gaccgataac tggggtgaag tcgtaacaag gtagccgtat 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 278 <211> 1531 <212> DNA <213> Clostridium_aldenense_sp <400> 278 tttgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagcg attaggatga agttttcgga tggattcctg gttgactgag tggcggacgg 120 gtgagtaacg cgtggataac ctgcctcaca ctgggggata acagttagaa atggctgcta 180 ataccgcata agcgcacagt accgcatggt acggtgtgaa aaacccaggt ggtgtgagat 240 ggatccgcgt ctgattagcc agttggcggg gtaacggccc accaaagcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggc ggaagcctga tgcagcgacg ccgcgtgagt 420 gaagaagtat ctcggtatgt aaagctctat cagcagggaa gaaaatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcgacgc aagtctggag tgaaagcccg 600 gggcccaacc ccgggactgc tttggaaact gtgctgctgg agtgcaggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac tgtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgaat gctaggtgtc ggggggcaaa gcccttcggt 840 gccgccgcta acgcaataag cattccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catccccctg accggcgcgt aacggtgccc ttccttcggg 1020 acaggggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatccttag tagccagcac gtcgtggtgg gcactctagg 1140 gagactgcca gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta 1200 tgatttgggc tacacacgtg ctacaatggc gtaaacaaag ggaggcgacc ctgcgaaggt 1260 aagcaaatcc caaaaataac gtcccagttc ggactgtagt ctgcaacccg actacacgaa 1320 gctggaatcg ctagtaatcg cggatcagaa tgccgcggtg aatacgttcc cgggtcttgt 1380 acacaccgcc cgtcacacca tgggagtcag caacgcccga agtcagtgac ccaaccttaa 1440 caggagggag ctgccgaagg cggggcaggt aactggggtg aagtcgtaac aaggtagccg 1500 tatcggaagg tgcggctgga tcacctcctt t 1531 <210> 279 <211> 1531 <212> DNA <213> Clostridium_sp <400> 279 acgagagttt gatcctggct caggacgaac gctggcggcg tgcctaacac atgcaagtcg 60 aacgagaatc tttgaacaga tcttttcgga gtgacgttca aagaggaaag tggcggacgg 120 gcgagtaacg cgtgagtaac ctgcccataa gagggggata atccatggaa acgtggacta 180 ataccgcata ttgtagttaa gttgcatgac ttgattatga aagatttatc gcttatggat 240 ggactcgcgt cagattagat agttggtgag gtaacggctc accaagtcaa cgatctgtag 300 ccgaactgag aggttgatcg gccgcattgg gactgagaca cggcccagac tcctacggga 360 ggcagcagtg gggaatattg cgcaatgggg gcaaccctga cgcagcaacg ccgcgtgcag 420 gaagaaggtc ttcggattgt aaactgttgt cgcaagggaa gaagacagtg acggtacctt 480 gtgagaaagt cacggctaac tacgtgccag cagccgcggt aatacgtagg tgacaagcgt 540 tgtccggatt tactgggtgt aaagggcgcg taggcggact gtcaagtcag tcgtgaaata 600 ccggggctta accccggggc tgcgattgaa actgacagcc ttgagtatcg gagaggaaag 660 cggaattcct agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg 720 cggctttctg gacgacaact gacgctgagg cgcgaaagtg tggggagcaa acaggattag 780 ataccctggt agtccacacc gtaaacgatg gatactaggt gtaggaggta tcgacccctt 840 ctgtgccgca gttaacacaa taagtatccc acctggggag tacgaccgca aggttgaaac 900 tcaaaggaat tgacgggggc ccgcacaagc agtggagtat gtggtttaat tcgaagcaac 960 gcgaagaacc ttacctgggc ttgacatccc tggaatcgag tagagatact tgagtgcctt 1020 cgggaatcag gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt 1080 taagtcccgc aacgagcgca acccctattg tcagttgcca tcattaagtt gggcactctg 1140 gcgagactgc cggtgacaaa tcggaggaag gtggggacga cgtcaaatca tcatgcccct 1200 tatgcccagg gctacacacg tactacaatg gccgataaca aagtgcagcg aaaccgtgag 1260 gtggagcgaa tcacaaaact cggtctcagt tcagattgca ggctgcaact cgcctgcatg 1320 aagttggaat tgctagtaat cgcggatcag aatgccgcgg tgaatacgtt cccgggcctt 1380 gtacacaccg cccgtcacac catgagagtc gataacaccc gaagcctgtg agctaacctt 1440 taggaggcag cagtcgaagg tggggttgat gattggggtg aagtcgtaac aaggtagccg 1500 tatcggaagg tgcggctgga tcacctcctt t 1531 <210> 280 <211> 1529 <212> DNA <213> Clostridium_lavalense <400> 280 tttgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaaca catgcaagtc 60 gaacgaagca tttcagatga agttttcgga tggattctga gatgactgag tggcggacgg 120 gtgagtaaca cgtggataac ctgcctcaca ctgggggaca acagttagaa atgactgcta 180 ataccgcata agcgcacagt accgcatggt acagtgtgaa aaactccggt ggtgtgagat 240 ggatccgcgt ctgattagcc agttggcggg gtaacggccc accaaagcga cgatcagtag 300 ccgacctgag agggtgaccg gccacattgg gactgagaca cggcccaaac tcctacggga 360 ggcagcagtg gggaatattg cacaatgggc gaaagcctga tgcagcgacg ccgcgtgagt 420 gaagaagtat ttcggtatgt aaagctctat cagcagggaa gataatgacg gtacctgact 480 aagaagcccc ggctaactac gtgccagcag ccgcggtaat acgtaggggg caagcgttat 540 ccggatttac tgggtgtaaa gggagcgtag acggcatggc aagtctgaag tgaaaaccca 600 gggctcaacc ctgggactgc tttggaaact gtcaagctag agtgcaggag aggtaagtgg 660 aattcctagt gtagcggtga aatgcgtaga tattaggagg aacaccagtg gcgaaggcgg 720 cttactggac tgtaactgac gttgaggctc gaaagcgtgg ggagcaaaca ggattagata 780 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt ggggggcaaa gcccttcggt 840 gccgtcgcaa acgcaataag cactccacct ggggagtacg ttcgcaagaa tgaaactcaa 900 aggaattgac ggggacccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga 960 agaaccttac caagtcttga catcctcttg accggcgtgt aacggcgcct ttccttcggg 1020 acaagggaga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag 1080 tcccgcaacg agcgcaaccc ttatccttag tagccagcat taagatgggc actctaggga 1140 gactgccagg gacaacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgaccct gcgaaggtga 1260 gcaaatctca aaaataacgt cccagttcgg actgtagtct gcaacccgac tacacgaagc 1320 tggaatcgct agtaatcgcg aatcagaatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagca acgcccgaag tcagtgaccc aactcgcaag 1440 agagggagct gccgaaggcg gggcaggtaa ctggggtgaa gtcgtaacaa ggtagccgta 1500 tcggaaggtg cggctggatc acctccttt 1529 <210> 281 <211> 1493 <212> DNA <213> Blautia_producta <400> 281 agagtttgat cctggctcag gatgaacgct ggcggcgtgc ttaacacatg caagtcgagc 60 gaagcactaa gacggatttc ttcggattga agtctttgtg actgagcggc ggacgggtga 120 gtaacgcgtg ggtaacctgc ctcatacagg gggataacag ttagaaatga ctgctaatac 180 cgcataagcg cacaggaccg catggtctgg tgtgaaaaac tccggtggta tgagatggac 240 ccgcgtctga ttagctagtt ggaggggtaa cggcccacca aggcgacgat cagtagccgg 300 cctgagaggg tgaacggcca cattgggact gagacacggc ccagactcct acgggaggca 360 gcagtgggga atattgcaca atgggggaaa ccctgatgca gcgacgccgc gtgaaggaag 420 aagtatctcg gtatgtaaac ttctatcagc agggaagaaa atgacggtac ctgactaaga 480 agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggcaag cgttatccgg 540 atttactggg tgtaaaggga gcgtagacgg aagagcaagt ctgatgtgaa aggctggggc 600 ttaaccccag gactgcattg gaaactgttg ttctagagtg ccggagaggt aagcggaatt 660 cctagtgtag cggtgaaatg cgtagatatt aggaggaaca ccagtggcga aggcggctta 720 ctggacggta actgacgttg aggctcgaaa gcgtggggag caaacaggat tagataccct 780 ggtagtccac gccgtaaacg atgaatacta ggtgtcgggt ggcaaagcca ttcggtgccg 840 cagcaaacgc aataagtatt ccacctgggg agtacgttcg caagaatgaa actcaaagga 900 attgacgggg acccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa 960 ccttaccaag tcttgacatc cctctgaccg tcccgtaacg gggacttccc ttcggggcag 1020 aggagacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc 1080 gcaacgagcg caacccttat ccttagtagc cagcacatga tggtgggcac tctagggaga 1140 ctgccgggga taacccggag gaaggcgggg acgacgtcaa atcatcatgc cccttatgat 1200 ttgggctaca cacgtgctac aatggcgtaa acaaagggaa gcgagacagc gatgttgagc 1260 gaatcccaaa aataacgtcc cagttcggac tgcagtctgc aactcgactg cacgaagctg 1320 gaatcgctag taatcgcgga tcagaatgcc gcggtgaata cgttcccggg tcttgtacac 1380 accgcccgtc acaccatggg agtcagtaac gcccgaagtc agtgacctaa ccgaaaggaa 1440 ggagctgccg aaggcgggac cgataactgg ggtgaagtcg taacaaggta acc 1493 <210> 282 <211> 1524 <212> DNA <213> Clostridium nexile <220> <221> misc_feature <222> (1)..(7) <223> n is a, c, g, or t <220> <221> misc_feature <222> (191)..(192) <223> n is a, c, g, or t <220> <221> misc_feature <222> (348) <223> n is a, c, g, or t <220> <221> misc_feature <222> (437) <223> n is a, c, g, or t <400> 282 nnnnnnngag atttgatcct ggctcaggat gaacgctggc cggccgtgct tacacatgca 60 gtcgaacgaa gcgcttaaac tggatttctt cggattgaag tttttgctga ctgagtggcg 120 gacgggtgag taacgcgtgg gtaacctgcc tcatacaggg ggataacagt tagaaatgac 180 tgctaatacc nnataagcgc acagtgctgc atggcacagt gtaaaaactc cggtggtatg 240 agatggaccc gcgtctgatt agctagttgg tggggtaacg gcctaccaag gcgacgatca 300 gtagccggcc tgagagggtg aacggccaca ttgggactga gacacggncc aaactcctac 360 gggaggcagc agtggggaat attgcacaat gggggaaacc ctgatgcagc gacgccgcgt 420 gagcgaagaa gtatttnggt atgtaaagct ctatcagcag ggaagaaaat gacggtacct 480 gactaagaag caccggctaa atacgtgcca gcagccgcgg taatacgtag gtgcaagcgt 540 tatccggatt tactgggtgt aaagggagcg tagacggttg tgtaagtctg atgtgaaagc 600 ccggggctca accccggact gcattggaaa ctatgtaact agagtgtcgg agaggtaagc 660 ggaattccta gtgtagcggt gaaatgcgta gatattagga ggaacaccag tggcgaaggc 720 ggcttactgg acgatcactg acgttgaggc tcgaaagcgt ggggagcaaa caggattaga 780 taccctggta gtccacgccg taaacgatga ctactaggtg tcggggagca aagctcttcg 840 gtgccgcagc aaacgcaata agtagtccac ctggggagta cgttcgcaag aatgaaactc 900 aaaggaattg acggggaccc gcacaagcgt ggagcatgtg gtttaattcg agcaacgcga 960 agaccttacc tggtcttgac atcccggtga ccggtccagt aatgggacct ttccttcggg 1020 acacggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt 1080 cccgcaacga gcgcaacccc tatcttcagt agccagcatt taaggtgggc actctggaga 1140 gactgccagg gataacctgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg 1200 accagggcta cacacgtgct acaatggcgt aaacaaaggg aagcgaacct gtgaggggaa 1260 gcaaatctca aaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgaccc aaccgtaagg 1440 agggagctgc cgaaggtggg accgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctcc 1524 <210> 283 <211> 1454 <212> DNA <213> Roseburia_inulinivorans <400> 283 ttgatcctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt cgaacgaagc 60 acttttacag atttcttcgg aatgaagttt tagtgactga gtggcggacg ggtgagtaac 120 gcgtgggtaa cctgcctcac acagggggat aacagttgga aacggctgct aataccgcat 180 aagcgcacag taccgcatgg tacagtgtga aaaactccgg tggtgtgaga tggacccgcg 240 tctgattagc tagttggcag ggcaacggcc taccaaggcg acgatcagta gccgacctga 300 gagggtgacc ggccacattg ggactgagac acggcccaaa ctcctacggg aggcagcagt 360 ggggaatatt gcacaatggg ggaaaccctg atgcagcgac gccgcgtgag cgaagaagta 420 tttcggtatg taaagctcta tcagcaggga agaagaaatg acggtacctg actaagaagc 480 accggctaaa tacgtgccag cagccgcggt aatacgtatg gtgcaagcgt tatccggatt 540 tactgggtgt aaagggagcg caggcggaag gctaagtctg atgtgaaagc ccggggctca 600 accccggtac tgcattggaa actggtcatc tagagtgtcg gaggggtaag tggaattcct 660 agtgtagcgg tgaaatgcgt agatattagg aggaacacca gtggcgaagg cggcttactg 720 gacgataact gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt 780 agtccacgcc gtaaacgatg aatactaggt gtcggaaagc acagcttttc ggtgccgccg 840 caaacgcatt aagtattcca cctggggagt acgttcgcaa gaatgaaact caaaggaatt 900 gacggggacc cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg cgaagaacct 960 taccaagtct tgacatcctt ctgaccggac agtaatgtgt cctttccttc gggacagaag 1020 tgacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 1080 acgagcgcaa cccttatccc cagtagccag cggttcggac gggcactctg aggagactgc 1140 cagggataac ctggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacttgg 1200 gctacacacg tgctacaatg gcgtaaacaa agggaagcga gaccgtgagg tggagcaaat 1260 cccaaaaata acgtctcagt tcggactgta gtctgcaacc cgactacacg aagctggaat 1320 cgctagtaat cgcagatcag aatgctgcgg tgaatacgtt cccgggtctt gtacacaccg 1380 cccgtcacac catgggagtt ggaaatgccc gaagtcagtg acccaaccgc aaggagggag 1440 ctgcgaaggc aggt 1454 <210> 284 <211> 1329 <212> DNA <213> Streptococcus_infantis <400> 284 gaacgggtga gtaacgcgta ggtaacctgc ctggtagcgg gggataacta ttggaaacga 60 tagctaatac cgcataacag tagatatcgc atgatagctg cttgaaaggt gcaattgcac 120 cactaccaga tggacctgcg ttgtattagc tagttggtga ggtaacggct caccaaggcr 180 acgatacata gccgacctga gagggtgatc ggccacactg ggactgagac acggcccaga 240 ctcctacggg aggcagcagt agggaatctt cggcaatgga cggaagtctg accgagcaac 300 gccgcgtgag tgaagaaggt tttcggatcg taaagctctg ttgtaagaga agaacgagtg 360 tgagagtgga aagttcacac tgtgacggta tcttaccaga aagggacggc taactacgtg 420 ccagcagccg cggtaatacg taggtcccga gcgttgtccg gatttattgg gcgtaaagcg 480 agcgcaggcg gttagataag tctgaagtta aaggctgtgg cttaaccata gtacgctttg 540 gaaactgttt aacttgagtg caagagggga gagtggaatt ccatgtgtag cggtgaaatg 600 cgtagatata tggaggaaca ccggtggcga aagcggctct ctggcttgta actgacgctg 660 aggctcgaaa gcgtggggag caaacaggat tagataccct ggtagtccac gccgtaaacg 720 atgagtgcta ggtgttagac cctttccggg gtttagtgcc gaagctaacg cattaagcac 780 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 840 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 900 ccctctgacc gctctagaga tagagttttc cttcgggaca gaggtgacag gtggtgcatg 960 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta 1020 ttgttagttg ccatcattya gttgggcact ctagcgagac tgccggtaat aaaccggagg 1080 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1140 atggttggta caacgagtcg caagccggtg acggcaagct aatctcttaa agccaatctc 1200 agttcggatt gtaggctgca actcgcctac atgaagtcgg aatcgctagt aatcgcggat 1260 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacgaga 1320 gtttgtaac 1329 <210> 285 <211> 1338 <212> DNA <213> Streptococcus_infantis <220> <221> misc_feature <222> (716) <223> n is a, c, g, or t <400> 285 tgcctaatac atgcaagtag aacgctgaag gaggagcttg ctcttctgga tgagttgcga 60 acgggtgagt aacgcgtagg taacctgcct ggtagcgggg gataactatt ggaaacgata 120 gctaataccg cataacagta gatatcgcat gatagctgct tgaaaggtgc aattgcacca 180 ctaccagatg gacctgcgtt gtattagcta gttggtgagg taacggctca ccaaggcaac 240 gatacatagc cgacctgaga gggtgatcgg ccacactggg actgagacac ggcccagact 300 cctacgggag gcagcagtag ggaatcttcg gcaatggacg gaagtctgac cgagcaacgc 360 cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt gtaagagaag aacgagtgtg 420 agagtggaaa gttcacactg tgacggtatc ttaccagaaa gggacggcta actacgtgcc 480 agcagccgcg gtaatacgta ggtcccgagc gttgtccgga tttattgggc gtaaagcgag 540 cgcaggcggt tagataagtc tgaagttaaa ggctgtggct taaccatagt acgctttgga 600 aactgtttaa cttgagtgca agaggggaga gtggaattcc atgtgtagcg gtgaaatgcg 660 tagatatatg gaggaacacc ggtggcgaaa gcggctctct ggcttgtaac tgacgngagg 720 ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 780 agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat taagcactcc 840 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc 900 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccc 960 tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg gtgcatggtt 1020 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctattg 1080 ttagttgcca tcattcagtt gggcactcta gcgagactgc cggtaataaa ccggaggaag 1140 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg 1200 gttggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc caatctcagt 1260 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag 1320 cacgccgcgg tgaatacg 1338 <210> 286 <211> 1462 <212> DNA <213> Streptococcus_infantis <400> 286 gacgaacgct ggcggcgtgc ctaatacatg caagtagaac gctgaaggag gagcttgctc 60 ttctggatga gttgcgaacg ggtgagtaac gcgtaggtaa cctgcctggt agcgggggat 120 aactattgga aacgatagct aataccgcat aacagtagat atcgcatgat agctgcttga 180 aaggtgcaat tgcaccacta ccagatggac ctgcgttgta ttagctagtt ggtgaggtaa 240 cggctcacca aggcaacgat acatagccga cctgagaggg tgatcggcca cactgggact 300 gagacacggc ccagactcct acgggaggca gcagtaggga atcttcggca atggacggaa 360 gtctgaccga gcaacgccgc gtgagtgaag aaggttttcg gatcgtaaag ctctgttgta 420 agagaagaac gagtgtgaga gtggaaagtt cacactgtga cggtatctta ccagaaaggg 480 acggctaact acgtgccagc agccgcggta atacgtaggt cccgagcgtt gtccggattt 540 attgggcgta aagcgagcgc aggcggttag ataagtctga agttaaaggc tgtggcttaa 600 ccatagtacg ctttggaaac tgtttaactt gagtgcaaga ggggagagtg gaattccatg 660 tgtagcggtg aaatgcgtag atatatggag gaacaccggt ggcgaaagcg gctctctggc 720 ttgtaactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat accctggtag 780 tccacgccgt aaacgatgag tgctaggtgt tagacccttt ccggggttta gtgccgaagc 840 taacgcatta agcactccgc ctggggagta cgaccgcaag gttgaaactc aaaggaattg 900 acgggggccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc gaagaacctt 960 accaggtctt gacatccctc tgaccgctct agagatagag ttttccttcg ggacagaggt 1020 gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa 1080 cgagcgcaac ccctattgtt agttgccatc atttagttgg gcactctagc gagactgccg 1140 gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc atgcccctta tgacctgggc 1200 tacacacgtg ctacaatggt tggtacaacg agtcgcaagc cggtgacggc aagctaatct 1260 cttaaagcca atctcagttc ggattgtagg ctgcaactcg cctacatgaa gtcggaatcg 1320 ctagtaatcg cggatcagca cgccgcggtg aatacgttcc cgggccttgt acacaccgcc 1380 cgtcacacca cgagagtttg taacacccga agtcggtgag gtaaccattt ggagccagcc 1440 gcctaaggtg ggatagatga tt 1462 <210> 287 <211> 1354 <212> DNA <213> Clostridium_sp_CL_6 <400> 287 gcgatgaagc ccttcggggt ggattagcgg cggacgggtg agtaacacgt gggtaacctg 60 ccttgtagag ggggatagcc ttccgaaagg aagattaata ccgcataaca tctttttatc 120 gcatggtaga aagatcaaag gagcaatccg ctacaagatg gacccgcggc gcattagcta 180 gttggtgagg taacggctca ccaaggcgac gatgcgtagc cgacctgaga gggtgatcgg 240 ccacattgga actgagacac ggtccagact cctacgggag gcagcagtgg ggaatattgc 300 gcaatggggg aaaccctgac gcagcaacgc cgcgtgaatg aagaaggcct tagggttgta 360 aagttctgtt tacggggacg ataatgacgg tacccgtggg gaagccacgg ctaactacgt 420 gccagcagcc gcggtaatac gtaggtggca agcgttgtcc ggatttactg ggcgtaaagg 480 atgcgtaggc ggatgtttaa gtgagatgtg aaatacccgg gctcaacttg ggtgctgcat 540 ttcaaactgg acatctagag tgcgggagag gaaagcggaa ttcctagtgt agcggtgaaa 600 tgcgtagaga ttaggaagaa caccagtggc gaaggcggct ttctggaccg taactgacgc 660 tgaggcatga aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgccgtaaa 720 cgatgaatac taggtgtagg aggtatcgac tccttctgtg ccgcagttaa cacaataagt 780 attccgcctg ggaagtacga tcgcaagatt aaaactcaaa ggaattgacg ggggcccgca 840 caagcagcgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc tagacttgac 900 atctcctgaa ttactcttaa tcgaggaagc ccttcggggc aggaagacag gtggtgcatg 960 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1020 tcattagttg ctaccattaa gttgagcact ctagtgagac tgccacggtt aacgtggagg 1080 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgtct agggctacac acgtgctaca 1140 atggtgaata caaatagatg caataccgcg aggtggagcc aaactataaa attcatccca 1200 gttcggattg cagtctgaaa ctcgactgca tgaagccgga gttgctagta atcgcgaatc 1260 agcatgtcgc ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accatgagag 1320 ctggtaacac ccgaagttcc gtgaggtaac cgca 1354 <210> 288 <211> 1542 <212> DNA <213> Streptococcus_mitis_oralis_pneumoniae <400> 288 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag 120 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt 180 ggatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt 240 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag 300 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta 360 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt 540 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt 600 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc 660 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac 720 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc 780 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc 840 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg 900 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta 960 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgaccg ctctagagat 1020 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 1080 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcattcag 1140 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat 1200 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc 1260 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa 1320 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg 1380 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg 1440 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta 1500 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tt 1542 <210> 289 <211> 1542 <212> DNA <213> Streptococcus_mitis_oralis_pneumoniae <400> 289 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag 120 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt 180 ggatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt 240 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag 300 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta 360 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt 540 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt 600 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc 660 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac 720 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc 780 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc 840 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg 900 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta 960 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgaccg ctctagagat 1020 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 1080 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcattcag 1140 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat 1200 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc 1260 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa 1320 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg 1380 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg 1440 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta 1500 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tt 1542 <210> 290 <211> 1542 <212> DNA <213> Streptococcus_mitis_oralis_pneumoniae <400> 290 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag 120 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt 180 ggatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt 240 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag 300 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta 360 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt 540 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt 600 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc 660 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac 720 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc 780 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc 840 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg 900 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta 960 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgaccg ctctagagat 1020 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 1080 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcattcag 1140 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat 1200 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc 1260 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa 1320 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg 1380 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg 1440 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta 1500 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tt 1542 <210> 291 <211> 1542 <212> DNA <213> Streptococcus_mitis_oralis_pneumoniae <400> 291 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag 120 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt 180 ggatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt 240 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag 300 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta 360 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt 420 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact 480 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt 540 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt 600 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc 660 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac 720 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc 780 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc 840 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg 900 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta 960 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgaccg ctctagagat 1020 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt 1080 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcattcag 1140 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat 1200 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc 1260 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa 1320 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg 1380 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg 1440 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta 1500 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tt 1542 <210> 292 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 292 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt gtcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttcgg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtaatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 293 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 293 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt gtcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttcgg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtgatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 294 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 294 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt gtcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttcgg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtaatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 295 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 295 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt atcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttcgg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtaatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 296 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 296 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt gtcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttcgg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtgatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 297 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 297 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt atcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttctg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtaatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 298 <211> 1539 <212> DNA <213> Proteus mirabilis <400> 298 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac aggagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggataac tactggaaac ggtggctaat accgcataat 180 gtctacggac caaagcaggg gctcttcgga ccttgcacta tcggatgaac ccatatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ctctagctgg tctgagagga 300 tgatcagcca cactgggact gagacacggc ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttag 420 ggttgtaaag tactttcagc ggggaggaag gtgataaggt taataccctt atcaattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtcaat taagtcagat 600 gtgaaagccc cgagcttaac ttgggaattg catctgaaac tggttggcta gagtcttgta 660 gaggggggta gaattccatg tgtagcggtg aaatgcgtag agatgtggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgctgt aaacgatgtc gatttagagg ttgtggtctt 840 gaaccgtggc ttctggagct aacgcgttaa atcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagcg aatcctttag agatagagga 1020 gtgccttctg gaacgctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagca cgtaatggtg 1140 ggaactcaaa ggagactgcc ggtgataaac cggaggaagg tggggatgac gtcaagtcat 1200 catggccctt acgagtaggg ctacacacgt gctacaatgg cagatacaaa gagaagcgac 1260 ctcgcgagag caagcggaac tcataaagtc tgtcgtagtc cggattggag tctgcaactc 1320 gactccatga agtcggaatc gctagtaatc gtagatcaga atgctacggt gaatacgttc 1380 ccgggccttg tacacaccgc ccgtcacacc atgggagtgg gttgcaaaag aagtaggtag 1440 cttaaccttc gggagggcgc ttaccacttt gtgattcatg actggggtga agtcgtaaca 1500 aggtaaccgt aggggaacct gcggttggat cacctcctt 1539 <210> 299 <211> 1572 <212> DNA <213> Pediococcus acidilactici <400> 299 atgagagttt gatcttggct caggatgaac gctggcggcg tgcctaatac atgcaagtcg 60 aacgaacttc cgttaattga tcaggacgtg cttgcactga atgagatttt aacacgaagt 120 gagtggcgga cgggtgagta acacgtgggt aacctgccca gaagcagggg ataacacctg 180 gaaacagatg ctaataccgt ataacagaga aaaccgcctg gttttctttt aaaagatggc 240 tctgctatca cttctggatg gacccgcggc gcattagcta gttggtgagg taacggctca 300 ccaaggcgat gatgcgtagc cgacctgaga gggtaatcgg ccacattggg actgagacac 360 ggcccagact cctacgggag gcagcagtag ggaatcttcc acaatggacg caagtctgat 420 ggagcaacgc cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacgtgggtg agagtaactg ttcacccagt gacggtattt aaccagaaag ccacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagcgagc gcaggcggtc ttttaagtct aatgtgaaag ccttcggctc aaccgaagaa 660 gtgcattgga aactgggaga cttgagtgca gaagaggaca gtggaactcc atgtgtagcg 720 gtgaaatgcg tagatatatg gaagaacacc agtggcgaag gcggctgtct ggtctgtaac 780 tgacgctgag gctcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gattactaag tgttggaggg tttccgccct tcagtgctgc agctaacgca 900 ttaagtaatc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaagaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tctgccaacc taagagatta ggcgttccct tcggggacag aatgacaggt 1080 ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttatt actagttgcc agcattcagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcaaatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggatggtaca acgagttgcg aaaccgcgag gtttagctaa tctcttaaaa 1320 ccattctcag ttcggactgt aggctgcaac tcgcctacac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagccggt ggggtaacct tttaggagct agccgtctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc tt 1572 <210> 300 <211> 1528 <212> DNA <213> Bifidobacterium dentium <400> 300 tatggagggt tcgattctgg ctcaggatga acgctggcgg cgtgcttaac acatgcaagt 60 cgaacgggat cccgggggtt cgctcccggg tgagagtggc gaacgggtga gtaatgcgtg 120 accgacctgc cccatacacc ggaatagctc ctggaaacgg gtggtaatgc cggatgctcc 180 ggttggatgc atgtccttcc gggaaagatt ccatcggtat gggatggggt cgcgtcctat 240 cagcttgatg gcggggtaac ggcccaccat ggcttcgacg ggtagccggc ctgagagggc 300 gaccggccac attgggactg agatacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tgggcgcaag cctgatgcag cgacgccgcg tgcgggatgg aggccttcgg 420 gttgtaaacc gcttttgatc gggagcaagc ccttcggggt gagtgtacct ttcgaataag 480 caccggctaa ctacgtgcca gcagccgcgg taatacgtag ggtgcaagcg ttatccggaa 540 ttattgggcg taaagggctc gtaggcggtt cgtcgcgtcc ggtgtgaaag cccatcgctt 600 aacggtgggt ctgcgccggg tacgggcggg ctggagtgcg gtaggggaga ctggaattcc 660 cggtgtaacg gtggaatgtg tagatatcgg gaagaacacc aatggcgaag gcaggtctct 720 gggccgtcac tgacgctgag gagcgaaagc gtggggagcg aacaggatta gataccctgg 780 tagtccacgc cgtaaacggt ggatgctgga tgtggggccc gttccacggg ttccgtgtcg 840 gagctaacgc gttaagcatc ccgcctgggg agtacggccg caaggctaaa actcaaagaa 900 attgacgggg gcccgcacaa gcggcggagc atgcggatta attcgatgca acgcgaagaa 960 ccttacctgg gcttgacatg ttcccgacag ccgtagagat atggcctccc ttcggggcgg 1020 gttcacaggt ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg 1080 caacgagcgc aaccctcgcc ctgtgttgcc agcacgtcat ggtgggaact cacgggggac 1140 cgccggggtc aactcggagg aaggtgggga tgacgtcaga tcatcatgcc ccttacgtcc 1200 agggcttcac gcatgctaca atggccggta cagcgggatg cgacatggcg acatggagcg 1260 gatccctgaa aaccggtctc agttcggatt ggagtctgca acccgactcc atgaaggcgg 1320 agtcgctagt aatcgcggat cagcaacgcc gcggtgaatg cgttcccggg ccttgtacac 1380 accgcccgtc aagtcatgaa agtgggcagc acccgaagcc ggtggcctaa ccccttgcgg 1440 gatggagccg tctaaggtga ggctcgtgat tgggactaag tcgtaacaag gtagccgtac 1500 cggaaggtgc ggctggatca cctccttt 1528 <210> 301 <211> 1540 <212> DNA <213> Proteus_penneri <400> 301 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtaac agaagaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga gggggagtaa ctactggaaa cggtggctaa taccgcatga 180 cgtctacgga ccaaagcagg ggctcttcgg accttgcgct atcggatgaa cccatatggg 240 attagctagt aggtgaggta aaggctcacc taggcgacga tctctagctg gtctgagagg 300 atgatcagcc acactgggac tgagacacgg cccagactcc tacgggaggc agcagtgggg 360 aatattgcac aatgggcgca agcctgatgc agccatgccg cgtgtatgaa gaaggcctta 420 gggttgtaaa gtactttcag cggggaggaa ggtgataaag ttaatacctt tatcaattga 480 cgttacccgc agaagaagca ccggctaact ccgtgccagc agccgcggta atacggaggg 540 tgcaagcgtt aatcggaatt actgggcgta aagcgcacgc aggcggtcaa ttaagtcaga 600 tgtgaaagcc ccgagcttaa cttgggaatt gcatctgaaa ctggttggct agagtcttgt 660 agaggggggt agaattccat ctgtagcggt gaaatgcgta gagatgtgga ggaataccgg 720 tggcgaaggc ggccccctgg acaaagactg acgctcaggt gcgaaagcgt ggggagcaaa 780 caggattaga taccctggta gtccacgctg taaacgatgt cgatttagag gttgtggtct 840 tgaaccgtgg cttctggagc taacgcgtta aatcgaccgc ctggggagta cggccgcaag 900 gttaaaactc aaatgaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc 960 gatgcaacgc gaagaacctt acctactctt gacatccagc ggatccttta gagatagagg 1020 agtgccttcg ggaacgctga gacaggtgct gcatggctgt cgtcagctcg tgttgtgaaa 1080 tgttgggtta agtcccgcaa cgagcgcaac ccttatcctt tgttgccagc gcgtgatggc 1140 gggaactcaa aggagactgc cggtgataaa ccggaggaag gtggggatga cgtcaagtca 1200 tcatggccct tacgagtagg gctacacacg tgctacaatg gcagatacaa agagaagcga 1260 cctcgcgaga gcaagcggaa ctcataaagt ctgtcgtagt ccggattgga gtctgcaact 1320 cgactccatg aagtcggaat cgctagtaat cgtagatcag aatgctacgg tgaatacgtt 1380 cccgggcctt gtacacaccg cccgtcacac catgggagtg ggttgcaaaa gaagtaggta 1440 gcttaacctt cgggagggcg cttaccactt tgtgattcat gactggggtg aagtcgtaac 1500 aaggtaaccg taggggaacc tgcggttgga tcacctcctt 1540 <210> 302 <211> 1381 <212> DNA <213> Proteus_penneri <400> 302 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaacg catgcaagtc 60 gaccggaaac agaggaaagc ttgctttctt gctgacgagc ggcggacggg tgagtaatgt 120 atggggatct gcccgataga ggggggtaac tattggaaaa agggggggta aataccgctt 180 gacgtctacg gccaaaagcc ggggcgcttc ggacctttcg ctattggatg aacccatatg 240 ggattagcta gtaggtgagg taaaggctca cctaggcgac gatctctagc tggtctgaga 300 ggatgatcag ccacactggg actgagacac ggcccagact cctacgggag gcagcagtgg 360 ggaatattgc acaatgggcg caagcctgat gcagccatgc cgcgtgtatg aagaaggcct 420 tagggttgta aagtactttc agcggggagg aaggtgataa agttaatacc tttatcaatt 480 gacgttaccc gcagaagaag caccggctaa ctccgtgcca gcagccgcgg taatacggag 540 ggtgcaagcg ttaatcggaa ttactgggcg taaagcgcac gcaggcggtc aattaagtca 600 gatgtgaaag ccccgagctt aacttgggaa ttgcatctga aactggttgg ctagagtctt 660 gtagaggggg ggtagaattc catgtgtagc ggtgaaatgc gtagagatgt ggaggaatac 720 cggtggcgaa ggcggccccc tggacaaaga ctgacgctca ggtgcgaaag cgtggggagc 780 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgtcgattta gaggttgtgg 840 tcttgaaccg tggcttctgg agctaacgcg ttaaatcgac cgcctgggga gtacggccgc 900 aaggttaaaa ctcaaatgaa ttgacggggg cccgcacaag cggtggagca tgtggtttaa 960 ttcgatgcaa cgcgaagaac cttacctact cttgacatcc agcgaatcct ttagagatag 1020 aggagtgcct tcgggaacgc tgagacaggt gctgcatggc tgtcgtcagc tcgtgttgtg 1080 aaatgttggg ttaagtcccg caacgagcgc aacccttatc ctttgttgcc agcgcgtgat 1140 ggcgggaact caaaggagac tgccggtgat aaaccggagg aaggtgggga tgacgtcaag 1200 tcatcatggc ccttacgagt agggctacac acgtgctaca atggcagata caaagagaag 1260 cgacctcgcg agagcaagcg gaactcataa agtctgtcgt agtccggatt ggagtctgca 1320 actcgactcc atgaagtcgg aatcgctagt aatcgtagat cagaatgcta cggtgaatac 1380 g 1381 <210> 303 <211> 1040 <212> DNA <213> Lactobacillus salivarius <220> <221> misc_feature <222> (1039)..(1040) <223> n is a, c, g, or t <400> 303 atgagagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg 60 aacgaaactt tcttacaccg aatgcttgca ttcatcgtaa gaagttgagt ggcggacggg 120 tgagtaacac gtgggtaacc tgcctaaaag aaggggataa cacttggaaa caggtgctaa 180 taccgtatat ctctaaggat cgcatgatcc ttagatgaaa gatggttctg ctatcgcttt 240 tagatggacc cgcggcgtat taactagttg gtggggtaac ggcctaccaa ggtgatgata 300 cgtagccgaa ctgagaggtt gatcggccac attgggactg agacacggcc caaactccta 360 cgggaggcag cagtagggaa tcttccacaa tggacgcaag tctgatggag caacgccgcg 420 tgagtgaaga aggtcttcgg atcgtaaaac tctgttgtta gagaagaaca cgagtgagag 480 taactgttca ttcgatgacg gtatctaacc agcaagtcac ggctaactac gtgccagcag 540 ccgcggtaat acgtaggtgg caagcgttgt ccggatttat tgggcgtaaa gggaacgcag 600 gcggtctttt aagtctgatg tgaaagcctt cggcttaacc ggagtagtgc attggaaact 660 ggaagacttg agtgcagaag aggagagtgg aactccatgt gtagcggtga aatgcgtaga 720 tatatggaag aacaccagtg gcgaaagcgg ctctctggtc tgtaactgac gctgaggttc 780 gaaagcgtgg gtagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgaat 840 gctaggtgtt ggagggtttc cgcccttcag tgccgcagct aacgcaataa gcattccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagcatgtg gtttaattcg aagcaacgcg aagaacctta ccaggtcttg acatcctttg 1020 accacctaag agattaggnn 1040 <210> 304 <211> 1560 <212> DNA <213> Veillonella dispar <400> 304 ttggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagag cgatggaagc ttgcttctat caatcttagt ggcgaacggg tgagtaacgc 120 gtaatcaacc tgcccttcag agggggacaa cagttggaaa cgactgctaa taccgcatac 180 gatctaacct cggcatcgag gatagatgaa aggtggcctc tatttataag ctatcactga 240 aggaggggat tgcgtctgat tagctagttg gaggggtaac ggcccaccaa ggcgatgatc 300 agtagccggt ctgagaggat gaacggccac attgggactg agacacggcc cagactccta 360 cgggaggcag cagtggggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg 420 tgagtgatga cggccttcgg gttgtaaagc tctgttaatc gggacgaaag gccttcttgc 480 gaatagttag aaggattgac ggtaccggaa tagaaagcca cggctaacta cgtgccagca 540 gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agcgcgcgca 600 ggcggattgg tcagtctgtc ttaaaagttc ggggcttaac cccgtgatgg gatggaaact 660 gccaatctag agtatcggag aggaaagtgg aattcctagt gtagcggtga aatgcgtaga 720 tattaggaag aacaccagtg gcgaaggcga ctttctggac gaaaactgac gctgaggcgc 780 gaaagccagg ggagcgaacg ggattagata ccccggtagt cctggccgta aacgatgggt 840 actaggtgta ggaggtatcg accccttctg tgccggagtt aacgcaataa gtaccccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagtatgtg gtttaattcg acgcaacgcg aagaacctta ccaggtcttg acattgatgg 1020 acagaactag agatagttcc tcttcttcgg aagccagaaa acaggtggtg cacggttgtc 1080 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttat 1140 gttgccagca ctttgggtgg gaactcatga gagactgccg cagacaatgc ggaggaaggc 1200 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgta ctacaatggg 1260 agttaataga cggaagcaat accgcgaggt ggagcaaacc cgagaaacac tctctcagtt 1320 cggatcgtag gctgcaactc gcctacgtga agtcggaatc gctagtaatc gcaggtcagc 1380 atactgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgaaagtcg 1440 gaagtgccca aagccggtgg ggtaaccttc gggagccagc cgtctaaggt aaagtcgatg 1500 attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat tacctccttt 1560 1560 <210> 305 <211> 1560 <212> DNA <213> Veillonella dispar <400> 305 ttggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagag cgatggaagc ttgcttctat caatcttagt ggcgaacggg tgagtaacgc 120 gtaatcaacc tgcccttcag agggggacaa cagttggaaa cgactgctaa taccgcatac 180 gatccaatct cggcatcgag gatagatgaa aggtggcctc tatttataag ctatcactga 240 aggaggggat tgcgtctgat tagctagttg gaggggtaac ggcccaccaa ggcgatgatc 300 agtagccggt ctgagaggat gaacggccac attgggactg agacacggcc cagactccta 360 cgggaggcag cagtggggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg 420 tgagtgatga cggccttcgg gttgtaaagc tctgttaatc gggacgaaag gccttcttgc 480 gaatagttag aaggattgac ggtaccggaa tagaaagcca cggctaacta cgtgccagca 540 gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agcgcgcgca 600 ggcggattgg tcagtctgtc ttaaaagttc ggggcttaac cccgtgatgg gatggaaact 660 gccaatctag agtatcggag aggaaagtgg aattcctagt gtagcggtga aatgcgtaga 720 tattaggaag aacaccagtg gcgaaggcga ctttctggac gaaaactgac gctgaggcgc 780 gaaagccagg ggagcgaacg ggattagata ccccggtagt cctggccgta aacgatgggt 840 actaggtgta ggaggtatcg accccttctg tgccggagtt aacgcaataa gtaccccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagtatgtg gtttaattcg acgcaacgcg aagaacctta ccaggtcttg acattgatgg 1020 acagaactag agatagttcc tcttcttcgg aagccagaaa acaggtggtg cacggttgtc 1080 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttat 1140 gttgccagca ctttgggtgg gaactcatga gagactgccg cagacaatgc ggaggaaggc 1200 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgta ctacaatggg 1260 agttaataga cggaagcaat accgcgaggt ggagcaaacc cgagaaacac tctctcagtt 1320 cggatcgtag gctgcaactc gcctacgtga agtcggaatc gctagtaatc gcaggtcagc 1380 atactgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgaaagtcg 1440 gaagtgccca aagccggtgg ggtaaccttc gggagccagc cgtctaaggt aaagtcgatg 1500 attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt 1560 1560 <210> 306 <211> 1560 <212> DNA <213> Veillonella dispar <400> 306 ttggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagag cgatggaagc ttgcttctat caatcttagt ggcgaacggg tgagtaacgc 120 gtaatcaacc tgcccttcag agggggacaa cagttggaaa cgactgctaa taccgcatac 180 gatctaacct cggcatcgag gatagatgaa aggtggcctc tatttataag ctatcactga 240 aggaggggat tgcgtctgat tagctagttg gaggggtaac ggcccaccaa ggcgatgatc 300 agtagccggt ctgagaggat gaacggccac attgggactg agacacggcc cagactccta 360 cgggaggcag cagtggggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg 420 tgagtgatga cggccttcgg gttgtaaagc tctgttaatc gggacgaaag gccttcttgc 480 gaatagttag aaggattgac ggtaccggaa tagaaagcca cggctaacta cgtgccagca 540 gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agcgcgcgca 600 ggcggattgg tcagtctgtc ttaaaagttc ggggcttaac cccgtgatgg gatggaaact 660 gccaatctag agtatcggag aggaaagtgg aattcctagt gtagcggtga aatgcgtaga 720 tattaggaag aacaccagtg gcgaaggcga ctttctggac gaaaactgac gctgaggcgc 780 gaaagccagg ggagcgaacg ggattagata ccccggtagt cctggccgta aacgatgggt 840 actaggtgta ggaggtatcg accccttctg tgccggagtt aacgcaataa gtaccccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagtatgtg gtttaattcg acgcaacgcg aagaacctta ccaggtcttg acattgatgg 1020 acagaactag agatagttcc tcttcttcgg aagccagaaa acaggtggtg cacggttgtc 1080 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttat 1140 gttgccagca ctttgggtgg gaactcatga gagactgccg cagacaatgc ggaggaaggc 1200 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgta ctacaatggg 1260 agttaataga cggaagcaat accgcgaggt ggagcaaacc cgagaaacac tctctcagtt 1320 cggatcgtag gctgcaactc gcctacgtga agtcggaatc gctagtaatc gcaggtcagc 1380 atactgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgaaagtcg 1440 gaagtgccca aagccggtgg ggtaaccttc gggagccagc cgtctaaggt aaagtcgatg 1500 attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt 1560 1560 <210> 307 <211> 1524 <212> DNA <213> Rothia dentocariosa <400> 307 acggagagtt tgattctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgatgaa gcctagcttg ctaggtggat tagtggcgaa cgggtgagta atacgtgagt 120 gacctacctt tgactctggg ataagcctgg gaaactgggt ctaataccgg atacgaccaa 180 tctccgcatg gggtgttggt ggaaagcgtt atggagtggt tttagatggg ctcacggcct 240 atcagcttgt tggtgaggta atggcttacc aaggcgacga cgggtagccg gcctgagagg 300 gtgaccggcc acactgggac tgagacacgg cccagactcc tacgggaggc agcagtgggg 360 aatattgcac aatgggcgca agcctgatgc agcgacgccg cgtgagggat gacggccttc 420 gggttgtaaa cctctgttag catcgaagaa gcgaaagtga cggtaggtgc agagaaagcg 480 ccggctaact acgtgccagc agccgcggta atacgtaggg cgcgagcgtt gtccggaatt 540 attgggcgta aagagcttgt aggcggttgg tcgcgtctgc tgtgaaaggc tggggcttaa 600 ccctggtttt gcagtgggta cgggctaact agagtgcagt aggggagact ggaattcctg 660 gtgtagcggt ggaatgcgca gatatcagga ggaacaccga tggcgaaggc aggtctctgg 720 gctgtaactg acgctgagaa gcgaaagcat ggggagcgaa caggattaga taccctggta 780 gtccatgccg taaacgttgg gcactaggtg tgggggacat tccacgtttt ccgcgccgta 840 gctaacgcat taagtgcccc gcctggggag tacggccgca aggctaaaac tcaaagaaat 900 tgacgggggc ccgcacaagc ggcggagcat gcggattaat tcgatgcaac gcgaagaacc 960 ttaccaaggc ttgacatata ctggactgcg tcagagatgg cgtttccctt cggggctggt 1020 atacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 1080 acgagcgcaa ccctcgttct atgttgccag cacgtgatgg tggggactca taggagactg 1140 ccggggtcaa ctcggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgtcttg 1200 ggcttcacgc atgctacaat ggccggtaca gagggttgcg atactgtgag gtggagctaa 1260 tccctaaaag ccggtctcag ttcggattgg ggtctgcaac tcgaccccat gaagtcggag 1320 tcgctagtaa tcgcagatca gcaacgctgc ggtgaatacg ttcccgggcc ttgtacacac 1380 cgcccgtcaa gtcacgaaag ttggtaacac ccgaagccgg tggcctaacc ctggtggggg 1440 gagccgtcga aggtgggact ggcgattggg actaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggatcacctc cttt 1524 <210> 308 <211> 1524 <212> DNA <213> Rothia dentocariosa <400> 308 acggagagtt tgattctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgatgaa gcctagcttg ctaggtggat tagtggcgaa cgggtgagta atacgtgagt 120 gacctacctt tgactctggg ataagcctgg gaaactgggt ctaataccgg atacgaccaa 180 tctccgcatg gggtgttggt ggaaagcgtt atggagtggt tttagatggg ctcacggcct 240 atcagcttgt tggtgaggta atggcttacc aaggcgacga cgggtagccg gcctgagagg 300 gtgaccggcc acactgggac tgagacacgg cccagactcc tacgggaggc agcagtgggg 360 aatattgcac aatgggcgca agcctgatgc agcgacgccg cgtgagggat gacggccttc 420 gggttgtaaa cctctgttag catcgaagaa gcgaaagtga cggtaggtgc agagaaagcg 480 ccggctaact acgtgccagc agccgcggta atacgtaggg cgcgagcgtt gtccggaatt 540 attgggcgta aagagcttgt aggcggttgg tcgcgtctgc tgtgaaaggc tggggcttaa 600 ccctggtttt gcagtgggta cgggctaact agagtgcagt aggggagact ggaattcctg 660 gtgtagcggt ggaatgcgca gatatcagga ggaacaccga tggcgaaggc aggtctctgg 720 gctgtaactg acgctgagaa gcgaaagcat ggggagcgaa caggattaga taccctggta 780 gtccatgccg taaacgttgg gcactaggtg tgggggacat tccacgtttt ccgcgccgta 840 gctaacgcat taagtgcccc gcctggggag tacggccgca aggctaaaac tcaaagaaat 900 tgacgggggc ccgcacaagc ggcggagcat gcggattaat tcgatgcaac gcgaagaacc 960 ttaccaaggc ttgacatata ctggactgcg tcagagatgg cgtttccctt cggggctggt 1020 atacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 1080 acgagcgcaa ccctcgttct atgttgccag cacgtgatgg tggggactca taggagactg 1140 ccggggtcaa ctcggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgtcttg 1200 ggcttcacgc atgctacaat ggccggtaca gagggttgcg atactgtgag gtggagctaa 1260 tccctaaaag ccggtctcag ttcggattgg ggtctgcaac tcgaccccat gaagtcggag 1320 tcgctagtaa tcgcagatca gcaacgctgc ggtgaatacg ttcccgggcc ttgtacacac 1380 cgcccgtcaa gtcacgaaag ttggtaacac ccgaagccgg tggcctaacc ctggtggggg 1440 gagccgtcga aggtgggact ggcgattggg actaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggatcacctc cttt 1524 <210> 309 <211> 1524 <212> DNA <213> Rothia dentocariosa <400> 309 acggagagtt tgattctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgatgaa gcctagcttg ctaggtggat tagtggcgaa cgggtgagta atacgtgagt 120 gacctacctt tgactctggg ataagcctgg gaaactgggt ctaataccgg atacgaccaa 180 tctccgcatg gggtgttggt ggaaagcgtt atggagtggt tttagatggg ctcacggcct 240 atcagcttgt tggtgaggta atggcttacc aaggcgacga cgggtagccg gcctgagagg 300 gtgaccggcc acactgggac tgagacacgg cccagactcc tacgggaggc agcagtgggg 360 aatattgcac aatgggcgca agcctgatgc agcgacgccg cgtgagggat gacggccttc 420 gggttgtaaa cctctgttag catcgaagaa gcgaaagtga cggtaggtgc agagaaagcg 480 ccggctaact acgtgccagc agccgcggta atacgtaggg cgcgagcgtt gtccggaatt 540 attgggcgta aagagcttgt aggcggttgg tcgcgtctgc tgtgaaaggc tggggcttaa 600 ccctggtttt gcagtgggta cgggctaact agagtgcagt aggggagact ggaattcctg 660 gtgtagcggt ggaatgcgca gatatcagga ggaacaccga tggcgaaggc aggtctctgg 720 gctgtaactg acgctgagaa gcgaaagcat ggggagcgaa caggattaga taccctggta 780 gtccatgccg taaacgttgg gcactaggtg tgggggacat tccacgtttt ccgcgccgta 840 gctaacgcat taagtgcccc gcctggggag tacggccgca aggctaaaac tcaaagaaat 900 tgacgggggc ccgcacaagc ggcggagcat gcggattaat tcgatgcaac gcgaagaacc 960 ttaccaaggc ttgacatata ctggactgcg tcagagatgg cgtttccctt cggggctggt 1020 atacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 1080 acgagcgcaa ccctcgttct atgttgccag cacgtgatgg tggggactca taggagactg 1140 ccggggtcaa ctcggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgtcttg 1200 ggcttcacgc atgctacaat ggccggtaca gagggttgcg atactgtgag gtggagctaa 1260 tccctaaaag ccggtctcag ttcggattgg ggtctgcaac tcgaccccat gaagtcggag 1320 tcgctagtaa tcgcagatca gcaacgctgc ggtgaatacg ttcccgggcc ttgtacacac 1380 cgcccgtcaa gtcacgaaag ttggtaacac ccgaagccgg tggcctaacc ctggtggggg 1440 gagccgtcga aggtgggact ggcgattggg actaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggatcacctc cttt 1524 <210> 310 <211> 1555 <212> DNA <213> Megasphaera_micronuciformis <400> 310 atggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgagagc gtagagaaag cttgcttttt ctacaatcta gtggcaaacg ggtgagtaac 120 gcgtaaacaa cctgccctac ggatggggac aacagctgga aacggctgct aataccgaat 180 acgttccgaa agtcgcatga ctgtcggaag aaaggatggc ctctatttat aagctatcgc 240 cggaggaggg gtttgcgtct gattagctag ttggaggggt aacggcccac caaggcgacg 300 atcagtagcc ggtctgagag gatgaacggc cacattggaa ctgagacacg gtccagactc 360 ctacgggagg cagcagtggg gaatcttccg caatgggcga aagcctgacg gagcaacgcc 420 gcgtgagtga agacggcctt cgggttgtaa agctctgtta tacgggacga ataatcttgt 480 ggttaatacc cataagaagt gacggtaccg taagagaaag ccacggctaa ctacgtgcca 540 gcagccgcgg taatacgtag gtggcaagcg ttgtccggaa ttattgggcg taaagggcgc 600 gcaggcggct tcttaagtct gtcttaaaag tgcggggctt aaccccgtga tgggatggaa 660 actgggaagc tcagagtatc ggagaggaaa gcggaattcc tagtgtagcg gtgaaatgcg 720 tagatattag gaggaacacc agtggcgaaa gcggctttct ggacgaaaac tgacgctgag 780 gcgcgaaagc caggggagcg aacgggatta gataccccgg tagtcctggc cgtaaacgat 840 gggtactagg tgtaggaggt atcgacccct tctgtgccgg agttaacgca ataagtaccc 900 cgcctgggga gtacggccgc aaggttgaaa ctcaaaggaa ttgacggggg cccgcacaag 960 cggtggagta tgtggtttaa ttcgacgcaa cgcgaagaac cttaccaagc cttgacattg 1020 atcgcaagga gtagagatac tctgttcttc ttcggaagac gagaaaacag gtggtgcacg 1080 gctgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta 1140 tcttctgtta ccagcacgta acggtgggga ctcaggagag actgccgcag acaatgcgga 1200 ggaaggcggg gatgacgtca agtcatcatg ccccttatgg cttgggctac acacgtacta 1260 caatggctct taatagaggg aggcgaagga gcgatccgga gcaaacccca aaaacagagt 1320 ctcagttcgg attgtaggct gcaactcgcc tacatgaagc aggaatcgct agtaatcgca 1380 ggtcagcata ctgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcacaccacg 1440 aaagtcattc acacccgaag ccggtgaggt aaccgcaagg agccagccgt cgaaggtggg 1500 ggcgatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg gctgg 1555 <210> 311 <211> 1560 <212> DNA <213> Veillonella atypica <400> 311 ttggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagag cgatggaagc ttgcttctat caatcttagt ggcgaacggg tgagtaacgc 120 gtaatcaacc tgcccttcag agggggacaa cagttggaaa cgactgctaa taccgcatac 180 gatccaatct cggcatcgag actggatgaa aggtggcctc tatttataag ctatcactga 240 aggaggggat tgcgtctgat tagctagttg gaggggtaac ggcccaccaa ggcgatgatc 300 agtagccggt ctgagaggat gaacggccac attgggactg agacacggcc cagactccta 360 cgggaggcag cagtggggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg 420 tgagtgatga cggccttcgg gttgtaaagc tctgttaatc gggacgaatg gttcttgtgc 480 gaatagtgcg aggatttgac ggtaccggaa tagaaagcca cggctaacta cgtgccagca 540 gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agcgcgcgca 600 ggcggattag ttagtctgtc ttaaaagttc ggggcttaac cccgtgatgg gatggaaact 660 gctgatctag agtatcggag aggaaagtgg aattcctagt gtagcggtga aatgcgtaga 720 tattaggaag aacaccagtg gcgaaggcga ctttctggac gaaaactgac gctgaggcgc 780 gaaagccagg ggagcgaacg ggattagata ccccggtagt cctggccgta aacgatgggt 840 actaggtgta ggaggtatcg accccttctg tgccggagtt aacgcaataa gtaccccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagtatgtg gtttaattcg acgcaacgcg aagaacctta ccaggtcttg acattgatgg 1020 acagaactag agatagttcc tcttcttcgg aagccagaaa acaggtggtg cacggttgtc 1080 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttat 1140 gttgccagca cttcgggtgg gaactcatga gagactgccg cagacaatgc ggaggaaggc 1200 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgta ctacaatggg 1260 agttaataga cggaagcgaa accgcgaggt ggagcaaacc cgagaaacac tctctcagtt 1320 cggatcgtag gctgcaactc gcctacgtga agtcggaatc gctagtaatc gcaggtcagc 1380 atactgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgaaagtcg 1440 gaagtgccca aagccggtgg ggtaaccttc gggagccagc cgtctaaggt aaagtcgatg 1500 attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt 1560 1560 <210> 312 <211> 1544 <212> DNA <213> Streptococcus thermophilus <400> 312 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctggg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgaagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tgggtcacct cctt 1544 <210> 313 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 313 atgaaagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtag 60 aacgctgaag agaggagctt gctcttcttg gatgagttgc gaacgggtga gtaacgcgta 120 ggtaacctgc cttgtagcgg gggataacta ttggaaacga tagctaatac cgcataacaa 180 tggatgacac atgtcattta tttgaaaggg gcaattgctc cactacaaga tggacctgcg 240 ttgtattagc tagtaggtga ggtaatggct cacctaggcg acgatacata gccgacctga 300 gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg aggcagcagt 360 agggaatctt cggcaatggg ggcaaccctg accgagcaac gccgcgtgag tgaagaaggt 420 tttcggatcg taaagctctg ttgtaagtca agaacgggtg tgagagtgga aagttcacac 480 tgtgacggta gcttaccaga aagggacggc taactacgtg ccagcagccg cggtaatacg 540 taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg gtttgataag 600 tctgaagtta aaggctgtgg ctcaaccata gttcgctttg gaaactgtca aacttgagtg 660 cagaagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata tggaggaaca 720 ccggtggcga aagcggctca ctggtctgta actgacgctg aggctcgaaa gcgtggggag 780 cgaacaggat tagataccct ggtagtccac gccgtaaacg atgagtgcta ggtgttggat 840 cctttccggg attcagtgcc gcagctaacg cattaagcac tccgcctggg gagtacgacc 900 gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag catgtggttt 960 aattcgaagc aacgcgaaga accttaccag gtcttgacat cccgatgcta tttctagaga 1020 tagaaagtta cttcggtaca tcggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattca 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcgagct aatctcttaa agccaatctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cttttggagc cagccgccta aggtgggaca gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1543 <210> 314 <211> 1544 <212> DNA <213> Streptococcus thermophilus <400> 314 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 315 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 315 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctggg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc 1140 agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgagtt 1260 gcgagtcggt gacggcgagc taatctctta aagccaatct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc 1440 ggtgaggtaa ccttttggag ccagccgcct aaggtgggac agatgattgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggtcacctc ctt 1543 <210> 316 <211> 1543 <212> DNA <213> Streptococcus thermophilus <400> 316 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta 60 gaacgctgaa gagaggagct tgctcttctt ggatgagttg cgaacgggtg agtaacgcgt 120 aggtaacctg ccttgtagcg ggggataact attggaaacg atagctaata ccgcataaca 180 atggatgaca catgtcattt atttgaaagg ggcaattgct ccactacaag atggacctgc 240 gttgtattag ctagtaggtg aggtaatggc tcacctaggc gacgatacat agccgacctg 300 agagggtgat cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag 360 tagggaatct tcggcaatgg gggcaaccct gaccgagcaa cgccgcgtga gtgaagaagg 420 ttttcggatc gtaaagctct gttgtaagtc aagaacgggt gtgagagtgg aaagttcaca 480 ctgtgacggt agcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac 540 gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc gggttgataa 600 gtctgaagtt aaaggctgtg gctcaaccat agttcgcttt ggaaactgtc aaacttgagt 660 gcagaagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac 720 accggtggcg aaagcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga 780 gcgaacagga ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttgga 840 tcctttccgg gattcagtgc cgcagctaac gcattaagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tcccgatgct atttctagag 1020 atagaaagtt acttcggtac atcggtgaca ggtgggcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattca 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggttggta caacgagttg 1260 cgagtcggtg acggcgagct aatctcttaa agccaatctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cttttggagc cagccgccta aggtgggaca gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct gggtcacctc ctt 1543 <210> 317 <211> 1561 <212> DNA <213> Lactobacillus animalis <400> 317 attgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgaaact tctttatcac cgagtgcttg cactcaccga taaagagttg agtggcgaac 120 gggtgagtaa cacgtgggca acctgcccaa aagaggggga taacacttgg aaacaggtgc 180 taataccgca taaccatagt taccgcatgg taactatgta aaaggtggct atgctaccgc 240 ttttggatgg gcccgcggcg cattagctag ttggtgaggt aaaggcttac caaggcaatg 300 atgcgtagcc gaactgagag gttgatcggc cacattggga ctgagacacg gcccaaactc 360 ctacgggagg cagcagtagg gaatcttcca caatgggcga aagcctgatg gagcaacgcc 420 gcgtgggtga agaaggtctt cggatcgtaa aaccctgttg ttagagaaga aagtgcgtga 480 gagtaactgt tcacgtttcg acggtatcta accagaaagc cacggctaac tacgtgccag 540 cagccgcggt aatacgtagg tggcaagcgt tatccggatt tattgggcgt aaagggaacg 600 caggcggtct tttaagtctg atgtgaaagc cttcggctta accggagtag tgcattggaa 660 actgggagac ttgagtgcag aagaggagag tggaactcca tgtgtagcgg tgaaatgcgt 720 agatatatgg aagaacacca gtggcgaaag cggctctctg gtctgtaact gacgctgagg 780 ttcgaaagcg tgggtagcaa acaggattag ataccctggt agtccacgcc gtaaacgatg 840 aatgctaagt gttggagggt ttccgccctt cagtgctgca gctaacgcaa taagcattcc 900 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc 960 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatctt 1020 ctgacaatcc tagagatagg actttccctt cggggacaga atgacaggtg gtgcatggtt 1080 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttattg 1140 ttagttgcca gcattaagtt gggcactcta gcaagactgc cggtgacaaa ccggaggaag 1200 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg 1260 gacggtacaa cgagtcgcaa gaccgcgagg tttagcaaat ctcttaaagc cgttctcagt 1320 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag 1380 catgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac catgagagtt 1440 tgtaacaccc aaagccggtg gggtaacctt ttggagccag ccgtctaagg tgggacagat 1500 gattggggtg aagtcgtaac aaggtagccg taggagaacc tgcggctgga tcacctcctt 1560 t 1561 <210> 318 <211> 1548 <212> DNA <213> Bilophila wadsworthia <400> 318 ctggagagtt tgattctggc tcagattgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgtgaaa gtccttcggg gcgagtaaag tggcgcacgg gtgagtaacg cgtggataat 120 ctacccttaa gatggggata acggctggaa acggtcgcta ataccgaata cgctcccgat 180 tttatcattg gggggaaaga tggcctctgc ttgcaagcta tcgcttaagg atgagtccgc 240 gtcccattag ctagttggcg gggtaacggc ccaccaaggc gacgatgggt agccggtctg 300 agaggatgac cggccacact ggaactggaa cacggtccag actcctacgg gaggcagcag 360 tggggaatat tgcgcaatgg gcgaaagcct gacgcagcga cgccgcgtga gggatgaagg 420 ttctcggatc gtaaacctct gtcagggggg aagaaacccc ctcgtgtgaa taatgcgagg 480 gcttgacggt acccccaaag gaagcaccgg ctaactccgt gccagcagcc gcggtaatac 540 ggagggtgca agcgttaatc ggaatcactg ggcgtaaagc gcacgtaggc ggcttggtaa 600 gtcaggggtg aaatcccaca gcccaactgt ggaactgcct ttgatactgc caggcttgag 660 taccggagag ggtggcggaa ttccaggtgt aggagtgaaa tccgtagata tctggaggaa 720 caccggtggc gaaggcggcc acctggacgg taactgacgc tgaggtgcga aagcgtgggt 780 agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgggtgc tgggtgctgg 840 gatgtatgtc tcggtgccgt agctaacgcg ataagcaccc cgcctgggga gtacggtcgc 900 aaggctgaaa ctcaaagaaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa 960 ttcgatgcaa cgcgaagaac cttacccagg cttgacatct agggaaccct tcggaaatga 1020 aggggtgccc ttcggggagc cctaagacag gtgctgcatg gctgtcgtca gctcgtgccg 1080 tgaggtgttg ggttaagtcc cgcaacgagc gcaaccccta tcttcagttg ccagcaggta 1140 aggctgggca ctctggagag accgccccgg tcaacgggga ggaaggtggg gacgacgtca 1200 agtcatcatg gcccttacgc ctggggctac acacgtacta caatggcgcg cacaaagggt 1260 agcgagaccg cgaggtggag ccaatcccaa aaaacgcgtc ccagtccgga ttggagtctg 1320 caactcgact ccatgaagtc ggaatcgcta gtaattcgag atcagcatgc tcgggtgaat 1380 gcgttcccgg gccttgtaca caccgcccgt cacaccacga aagtcggttt tacccgaagc 1440 cggtgagcta actcgcaaga ggagcagccg tctacggtag ggccgatgat tggggtgaag 1500 tcgtaacaag gtagccgtag gggaacctgc ggctggatca cctccttt 1548 <210> 319 <211> 1548 <212> DNA <213> Bilophila wadsworthia <400> 319 ctggagagtt tgattctggc tcagattgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgtgaaa gtccttcggg gcgagtaaag tggcgcacgg gtgagtaacg cgtggataat 120 ctacccttaa gatggggata acggctggaa acggtcgcta ataccgaata cgctcccgat 180 tttatcgttg gggggaaaga tggcctctgc ttgcaagcta tcgcttaagg atgagtccgc 240 gtcccattag ctagttggcg gggtaacggc ccaccaaggc gacgatgggt agccggtctg 300 agaggatgac cggccacact ggaactggaa cacggtccag actcctacgg gaggcagcag 360 tggggaatat tgcgcaatgg gcgaaagcct gacgcagcga cgccgcgtga gggatgaagg 420 ttctcggatc gtaaacctct gtcagggggg aagaaacccc ctcgtgtgaa taatgcgagg 480 gcttgacggt acccccaaag gaagcaccgg ctaactccgt gccagcagcc gcggtaatac 540 ggagggtgca agcgttaatc ggaatcactg ggcgtaaagc gcacgtaggc ggcttggtaa 600 gtcaggggtg aaatcccaca gcccaactgt ggaactgcct ttgatactgc caggcttgag 660 taccggagag ggtggcggaa ttccaggtgt aggagtgaaa tccgtagata tctggaggaa 720 caccggtggc gaaggcggcc acctggacgg taactgacgc tgaggtgcga aagcgtgggt 780 agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgggtgc tgggtgctgg 840 gatgtatgtc tcggtgccgt agctaacgcg ataagcaccc cgcctgggga gtacggtcgc 900 aaggctgaaa ctcaaagaaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa 960 ttcgatgcaa cgcgaagaac cttacccagg cttgacatct agggaaccct tcggaaatga 1020 aggggtgccc ttcggggagc cctaagacag gtgctgcatg gctgtcgtca gctcgtgccg 1080 tgaggtgttg ggttaagtcc cgcaacgagc gcaaccccta tcttcagttg ccagcaggta 1140 aggctgggca ctctggagag accgccccgg tcaacgggga ggaaggtggg gacgacgtca 1200 agtcatcatg gcccttacgc ctggggctac acacgtacta caatggcgcg cacaaagggt 1260 agcgagaccg cgaggtggag ccaatcccaa aaaacgcgtc ccagtccgga ttggagtctg 1320 caactcgact ccatgaagtc ggaatcgcta gtaattcgag atcagcatgc tcgggtgaat 1380 gcgttcccgg gccttgtaca caccgcccgt cacaccacga aagtcggttt tacccgaagc 1440 cggtgagcta actcgcaaga ggagcagccg tctacggtag ggccgatgat tggggtgaag 1500 tcgtaacaag gtagccgtag gggaacctgc ggctggatca cctccttt 1548 <210> 320 <211> 1548 <212> DNA <213> Bilophila wadsworthia <400> 320 ctggagagtt tgattctggc tcagattgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgtgaaa gtccttcggg gcgagtaaag tggcgcacgg gtgagtaacg cgtggataat 120 ctacccttaa gatggggata acggctggaa acggtcgcta ataccgaata cgctcccgat 180 tttatcattg gggggaaaga tggcctctgc ttgcaagcta tcgcttaagg atgagtccgc 240 gtcccattag ctagttggcg gggtaacggc ccaccaaggc gacgatgggt agccggtctg 300 agaggatgac cggccacact ggaactggaa cacggtccag actcctacgg gaggcagcag 360 tggggaatat tgcgcaatgg gcgaaagcct gacgcagcga cgccgcgtga gggatgaagg 420 ttctcggatc gtaaacctct gtcagggggg aagaaacccc ctcgtgtgaa taatgcgagg 480 gcttgacggt acccccaaag gaagcaccgg ctaactccgt gccagcagcc gcggtaatac 540 ggagggtgca agcgttaatc ggaatcactg ggcgtaaagc gcacgtaggc ggcttggtaa 600 gtcaggggtg aaatcccaca gcccaactgt ggaactgcct ttgatactgc caggcttgag 660 taccggagag ggtggcggaa ttccaggtgt aggagtgaaa tccgtagata tctggaggaa 720 caccggtggc gaaggcggcc acctggacgg taactgacgc tgaggtgcga aagcgtgggt 780 agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgggtgc tgggtgctgg 840 gatgtatgtc tcggtgccgt agctaacgcg ataagcaccc cgcctgggga gtacggtcgc 900 aaggctgaaa ctcaaagaaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa 960 ttcgatgcaa cgcgaagaac cttacccagg cttgacatct agggaaccct tcggaaatga 1020 aggggtgccc ttcggggagc cctaagacag gtgctgcatg gctgtcgtca gctcgtgccg 1080 tgaggtgttg ggttaagtcc cgcaacgagc gcaaccccta tcttcagttg ccagcaggta 1140 aggctgggca ctctggagag accgccccgg tcaacgggga ggaaggtggg gacgacgtca 1200 agtcatcatg gcccttacgc ctggggctac acacgtacta caatggcgcg cacaaagggt 1260 agcgagaccg cgaggtggag ccaatcccaa aaaacgcgtc ccagtccgga ttggagtctg 1320 caactcgact ccatgaagtc ggaatcgcta gtaattcgag atcagcatgc tcgggtgaat 1380 gcgttcccgg gccttgtaca caccgcccgt cacaccacga aagtcggttt tacccgaagc 1440 cggtgagcta actcgcaaga ggagcagccg tctacggtag ggccgatgat tggggtgaag 1500 tcgtaacaag gtagccgtag gggaacctgc ggctggatca cctccttt 1548 <210> 321 <211> 1548 <212> DNA <213> Bilophila wadsworthia <400> 321 ctggagagtt tgattctggc tcagattgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgtgaaa gtccttcggg gcgagtaaag tggcgcacgg gtgagtaacg cgtggataat 120 ctacccttaa gatggggata acggctggaa acggtcgcta ataccgaata cgctcccgat 180 tttatcgttg gggggaaaga tggcctctgc ttgcaagcta tcgcttaagg atgagtccgc 240 gtcccattag ctagttggcg gggtaacggc ccaccaaggc gacgatgggt agccggtctg 300 agaggatgac cggccacact ggaactggaa cacggtccag actcctacgg gaggcagcag 360 tggggaatat tgcgcaatgg gcgaaagcct gacgcagcga cgccgcgtga gggatgaagg 420 ttctcggatc gtaaacctct gtcagggggg aagaaacccc ctcgtgtgaa taatgcgagg 480 gcttgacggt acccccaaag gaagcaccgg ctaactccgt gccagcagcc gcggtaatac 540 ggagggtgca agcgttaatc ggaatcactg ggcgtaaagc gcacgtaggc ggcttggtaa 600 gtcaggggtg aaatcccaca gcccaactgt ggaactgcct ttgatactgc caggcttgag 660 taccggagag ggtggcggaa ttccaggtgt aggagtgaaa tccgtagata tctggaggaa 720 caccggtggc gaaggcggcc acctggacgg taactgacgc tgaggtgcga aagcgtgggt 780 agcaaacagg attagatacc ctggtagtcc acgctgtaaa cgatgggtgc tgggtgctgg 840 gatgtatgtc tcggtgccgt agctaacgcg ataagcaccc cgcctgggga gtacggtcgc 900 aaggctgaaa ctcaaagaaa ttgacggggg cccgcacaag cggtggagta tgtggtttaa 960 ttcgatgcaa cgcgaagaac cttacccagg cttgacatct agggaaccct tcggaaatga 1020 aggggtgccc ttcggggagc cctaagacag gtgctgcatg gctgtcgtca gctcgtgccg 1080 tgaggtgttg ggttaagtcc cgcaacgagc gcaaccccta tcttcagttg ccagcaggta 1140 aggctgggca ctctggagag accgccccgg tcaacgggga ggaaggtggg gacgacgtca 1200 agtcatcatg gcccttacgc ctggggctac acacgtacta caatggcgcg cacaaagggt 1260 agcgagaccg cgaggtggag ccaatcccaa aaaacgcgtc ccagtccgga ttggagtctg 1320 caactcgact ccatgaagtc ggaatcgcta gtaattcgag atcagcatgc tcgggtgaat 1380 gcgttcccgg gccttgtaca caccgcccgt cacaccacga aagtcggttt tacccgaagc 1440 cggtgagcta actcgcaaga ggagcagccg tctacggtag ggccgatgat tggggtgaag 1500 tcgtaacaag gtagccgtag gggaacctgc ggctggatca cctccttt 1548 <210> 322 <211> 1561 <212> DNA <213> Veillonella parvula <400> 322 ttggagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgaagag cgatggaagc ttgcttctat caatcttagt ggcgaacggg tgagtaacgc 120 gtaatcaacc tgcccttcag agggggacaa cagttggaaa cgactgctaa taccgcatac 180 gatctaatct cggcatcgag gatagatgaa aggtggcctc tacatgtaag ctatcactga 240 aggaggggat tgcgtctgat tagctagttg gaggggtaac ggcccaccaa ggcgatgatc 300 agtagccggt ctgagaggat gaacggccac attgggactg agacacggcc cagactccta 360 cgggaggcag cagtggggaa tcttccgcaa tggacgaaag tctgacggag caacgccgcg 420 tgagtgatga cggccttcgg gttgtaaagc tctgttaatc gggacgaaag gccttcttgc 480 gaacagttag aaggattgac ggtaccggaa tagaaagcca cggctaacta cgtgccagca 540 gccgcggtaa tacgtaggtg gcaagcgttg tccggaatta ttgggcgtaa agcgcgcgca 600 ggcggatcag tcagtctgtc ttaaaagttc ggggcttaac cccgtgatgg gatggaaact 660 gctgatctag agtatcggag aggaaagtgg aattcctagt gtagcggtga aatgcgtaga 720 tattaggaag aacaccagtg gcgaaggcga ctttctggac gaaaactgac gctgaggcgc 780 gaaagccagg ggagcgaacg ggattagata ccccggtagt cctggccgta aacgatgggt 840 actaggtgta ggaggtatcg accccttctg tgccggagtt aacgcaataa gtaccccgcc 900 tggggagtac gaccgcaagg ttgaaactca aaggaattga cgggggcccg cacaagcggt 960 ggagtatgtg gtttaattcg acgcaacgcg aagaacctta ccaggtcttg acattgatgg 1020 acagaactag agatagttcc tcttcttcgg aagccagaaa acaggtggtg cacggttgtc 1080 gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac gagcgcaacc cctatcttat 1140 gttgccagca cgtaatggtg ggaactcatg agagactgcc gcagacaatg cggaggaagg 1200 cggggatgac gtcaaatcat catgcccctt atgacctggg ctacacacgt actacaatgg 1260 gagttaatag acggaagcga gatcgcgaga tggagcaaac ccgagaaaca ctctctcagt 1320 tcggatcgta ggctgcaact cgcctacgtg aagtcggaat cgctagtaat cgcaggtcag 1380 catactgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac cacgaaagtc 1440 ggaagtgccc aaagccggtg gggtaacctt cgggagccag ccgtctaagg taaagtcgat 1500 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt 1560 t 1561 <210> 323 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 323 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttac acggaggaag ttttcggatg gaatcggtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacggaacc gcatggttcc gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgcc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccccctgaa tatcttgtaa aaaagagatg ccttcgggac 1020 aggggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaggctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 324 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 324 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttat atcgaggaag ttttcggatg gaatcagtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacagcttc acatgaagca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgtc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tccccctgac tctcctgtaa aagagtgagg ccttcgggac 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaagctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 325 <211> 1527 <212> DNA <213> Lachnospiraceae_bacterium_3_1_57FAA_CT1 <400> 325 agagagtttg atcctggctc aggatgaacg ctggcggcgt gcctaacaca tgcaagtcga 60 acgaagttac acagaggaag ttttcggatg gaatcggtat aacttagtgg cggacgggtg 120 agtaacgcgt gggaaacctg ccctgtaccg ggggataaca cttagaaata ggtgctaata 180 ccgcataagc gcacggattc acatgaagca gtgtgaaaaa ctccggtggt acaggatggt 240 cccgcgtctg attagccagt tggcagggta acggcctacc aaagcgacga tcagtagccg 300 gcctgagagg gtgaacggcc acattgggac tgagacacgg cccaaactcc tacgggaggc 360 agcagtgggg aatattgcac aatgggggaa accctgatgc agcgacgccg cgtgagtgaa 420 gaagtatttc ggtatgtaaa gctctatcag cagggaagaa aatgacggta cctgactaag 480 aagccccggc taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg 540 gatttactgg gtgtaaaggg agcgtagacg gcatggcaag ccagatgtga aaacccaggg 600 ctcaaccttg ggattgcatt tggaactgtc aggctggagt gcaggagagg taagcggaat 660 tcctagtgta gcggtgaaat gcgtagatat taggaggaac accagtggcg aaggcggctt 720 actggactgt aactgacgtt gaggctcgaa agcgtgggga gcaaacagga ttagataccc 780 tggtagtcca cgcggtaaac gatgattgct aggtgtaggt gggtatggac ccatcggtgc 840 cgcagctaac gcaataagca atccacctgg ggagtacgtt cgcaagaatg aaactcaaag 900 gaattgacgg ggacccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag 960 aaccttacca agtcttgaca tcccaatgac gcacctgtaa agaggtgttc ccttcggggc 1020 attggagaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc 1080 ccgcaacgag cgcaaccctt attcttagta gccagcaggt aaagctgggc actctaagga 1140 gactgccggg gataacccgg aggaaggcgg ggatgacgtc aaatcatcat gccccttatg 1200 atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcgagaca gtgatgtgga 1260 gcaaatccca gaaataacgt ctcagttcgg attgtagtct gcaactcgac tacatgaagc 1320 tggaatcgct agtaatcgcg aatcagcatg tcgcggtgaa tacgttcccg ggtcttgtac 1380 acaccgcccg tcacaccatg ggagttggaa atgcccgaag tctgtgacct aaccgaaagg 1440 gaggagcagc cgaaggcagg tctgataact ggggtgaagt cgtaacaagg tagccgtatc 1500 ggaaggtgcg gctggatcac ctccttt 1527 <210> 326 <211> 1536 <212> DNA <213> Erysipelotrichaceae_bacterium_2_2_44A <400> 326 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagct tcaggaagct tgcttccaaa gagacttagt ggcgaacggg tgagtaacac 120 gtaggtaacc tgcccatgtg tccgggataa ctgctggaaa cggtagctaa aaccggatag 180 gtatacagag cgcatgctca gtatattaaa gcgcccatca aggcgtgaac atggatggac 240 ctgcggcgca ttagctagtt ggtgaggtaa cggcccacca aggcgatgat gcgtagccgg 300 cctgagaggg taaacggcca cattgggact gagacacggc ccaaactcct acgggaggca 360 gcagtaggga attttcgtca atgggggaaa ccctgaacga gcaatgccgc gtgagtgaag 420 aaggtcttcg gatcgtaaag ctctgttgta agtgaagaac ggctcataga ggaaatgcta 480 tgggagtgac ggtagcttac cagaaagcca cggctaacta cgtgccagca gccgcggtaa 540 tacgtaggtg gcaagcgtta tccggaatca ttgggcgtaa agggtgcgta ggtggcgtac 600 taagtctgta gtaaaaggca atggctcaac cattgtaagc tatggaaact ggtatgctgg 660 agtgcagaag agggcgatgg aattccatgt gtagcggtaa aatgcgtaga tatatggagg 720 aacaccagtg gcgaaggcgg tcgcctggtc tgtaactgac actgaggcac gaaagcgtgg 780 ggagcaaata ggattagata ccctagtagt ccacgccgta aacgatgaga actaagtgtt 840 ggaggaattc agtgctgcag ttaacgcaat aagttctccg cctggggagt atgcacgcaa 900 gtgtgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagtatg tggtttaatt 960 cgaagcaacg cgaagaacct taccaggcct tgacatggaa acaaataccc tagagatagg 1020 gggataatta tggatcacac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tgtcgcatgt taccagcatc aagttgggga 1140 ctcatgcgag actgccggtg acaaaccgga ggaaggtggg gatgacgtca aatcatcatg 1200 ccccttatgg cctgggctac acacgtacta caatggcgac cacaaagagc agcgacttgg 1260 tgacaagaag cgaatctcat aaaggtcgtc tcagttcgga ttgaagtctg caactcgact 1320 tcatgaagtc ggaatcgcta gtaatcgcag atcagcatgc tgcggtgaat acgttctcgg 1380 gccttgtaca caccgcccgt caaaccatgg gagtcagtaa tacccgaagc cggtggcata 1440 accgtaagga gtgagccgtc gaaggtagga ccgatgactg gggttaagtc gtaacaaggt 1500 atccctacgg gaacgtgggg atggatcacc tccttt 1536 <210> 327 <211> 1526 <212> DNA <213> Rothia_mucilaginosa <400> 327 acggagagtt tgattctggc tcaggacgaa cgctggcggc gtgcttaaca catgcaagtc 60 gaacgatgaa gcctagcttg ctaggtggat tagtggcgaa cgggtgagta atacgtgagt 120 aacctacctt taactctggg ataagcctgg gaaactgggt ctaataccgg atacgaccaa 180 tctccgcatg gggtgttggt ggaaagcgtt atgtagtggt tatagatggg ctcacggcct 240 atcagcttgt tggtgaggta acggctcacc aaggcgacga cgggtagccg gcctgagagg 300 gtgaccggcc acactgggac tgagacacgg cccagactcc tacgggaggc agcagtgggg 360 aatattgcac aatgggcgca agcctgatgc agcgacgccg cgtgagggat gacggccttc 420 gggttgtaaa cctctgttag cagggaagaa gagaaattga cggtacctgc agagaaagcg 480 ccggctaact acgtgccagc agccgcggta atacgtaggg cgcgagcgtt gtccggaatt 540 attgggcgta aagagcttgt aggcggtttg tcgcgtctgc tgtgaaaggc cggggcttaa 600 ctccgtgtat tgcagtgggt acgggcagac tagagtgcag taggggagac tggaattcct 660 ggtgtagcgg tggaatgcgc agatatcagg aggaacaccg atggcgaagg caggtctctg 720 ggctgtaact gacgctgaga agcgaaagca tggggagcga acaggattag ataccctggt 780 agtccatgcc gtaaacgttg ggcactaggt gtgggggaca ttccacgttt tccgcgccgt 840 agctaacgca ttaagtgccc cgcctgggga gtacggccgc aaggctaaaa ctcaaagaaa 900 ttgacggggg cccgcacaag cggcggagca tgcggattaa ttcgatgcaa cgcgaagaac 960 cttaccaagg cttgacatat actggaccgc atcagagatg gtgtttccct tcggggctgg 1020 tatacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc 1080 aacgagcgca accctcgttc tatgttgcca gcacgttatg gtggggactc ataggagact 1140 gccggggtca actcggagga aggtggggat gacgtcaaat catcatgccc cttatgtctt 1200 gggcttcacg catgctacaa tggccggtac agagggttgc gatactgtga ggtggagcta 1260 atccctaaaa gccggtctca gttcggattg gggtctgcaa ctcgacccca tgaagtcgga 1320 gtcgctagta atcgcagatc agcaacgctg cggtgaatac gttcccgggc cttgtacaca 1380 ccgcccgtca agtcacgaaa gttggtaaca cccaaagccg gtggcctaac ccttcgggga 1440 gggagccgtc taaggtggga ttggcgattg ggactaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggatcacc tccttt 1526 <210> 328 <211> 1563 <212> DNA <213> Lactobacillus rhamnosus <400> 328 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tgattattga aaggtgcttg catcttgatt tgattttgaa cgagtggcgg 120 acgggtgagc aacacgtggg taactgccct tagtggggga tacatttgga aacagatgct 180 aataccgcat aaatccaaga accgcatggt tcttggctga aagatggcgt aagctatcgc 240 ttttggatgg acccgcggcg tattagctag ttggtgaggt aacggctcac caaggcaatg 300 atacgtagcc gaactgagag gttgatcggc cacattggga ctgagacacg gcccaaactc 360 ctacgggagg cagcagtagg gaatcttcca caatggacgc aagtctgatg gagcaacgcc 420 gcgtgagtga agaaggcttt cgggtcgtaa aactctgttg ttggagaaga atggtcggca 480 gagtaactgt tgtcggcgtg acggtatcca accagaaagc cacggctaac tacgtgccag 540 cagccgcggt aatacgtagg tggcaagcgt tatccggatt tattgggcgt aaagcgagcg 600 caggcggttt tttaagtctg atgtgaaagc cctcggctta accgaggaag tgcatcggaa 660 actgggaaac ttgagtgcag aagaggacag tggaactcca tgtgtagcgg tgaaatgcgt 720 agatatatgg aagaacacca gtggcgaagg cggctgtctg gtctgtaact gacgctgagg 780 ctcgaaagca tgggtagcga acaggattag ataccctggt agtccatgcc gtaaacgatg 840 aatgctaggt gttggagggt ttccgccctt cagtgccgca gctaacgcat taagcattcc 900 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc 960 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatctt 1020 ttgatcacct gagagatcag gtttcccctt cgggggcaaa atgacaggtg gtgtatggtt 1080 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccttatga 1140 ctagttgcca gcatttagtt gggcactcta gtaagactgc cggtgacaaa ccggaggaag 1200 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg 1260 gatggtacaa cgagttgcga gaccgcgagg tcaagctaat ctcttaaagc cattctcagt 1320 tcggactgta ggctgcaact cgcctacacg aagtcggaat cgctagtaat cgcggatcag 1380 cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac catgagagtt 1440 tgtaacaccc gaagccggtg gcgtaaccct tttagggagc gagccgtcta aggtgggaca 1500 aatgattagg gtgaagtcgt aacaaggtag ccgtaggaga acctgcggct ggatcacctc 1560 ctt 1563 <210> 329 <211> 1567 <212> DNA <213> Lactobacillus rhamnosus <400> 329 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tgattattga aaggtgcttg catcttgatt taattttgaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg cataaatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaacggct caccaaggca 300 atgaatacgt agccgaactg agaggttgat cggccacatt gggactgaga cacggcccaa 360 actcctacgg gaggcagcag tagggaatct tccacaatgg acgcaagtct gatggagcaa 420 cgccgcgtga gtgaagaagg ctttcgggtc gtaaaactct gttgttggag aagaatggtc 480 ggcagagtaa ctgttgtcgg cgtgacggta tccaaccaga aagccacggc taactacgtg 540 ccagcagccg cggtaatacg taggtggcaa gcgttatccg gatttattgg gcgtaaagcg 600 agcgcaggcg gttttttaag tctgatgtga aagccctcgg cttaaccgag gaagtgcatc 660 ggaaactggg aaacttgagt gcagaagagg acagtggaac tccatgtgta gcggtgaaat 720 gcgtagatat atggaagaac accagtggcg aaggcggctg tctggtctgt aactgacgct 780 gaggctcgaa agcatgggta gcgaacagga ttagataccc tggtagtcca tgccgtaaac 840 gatgaatgct aggtgttgga gggtttccgc ccttcagtgc cgcagctaac gcattaagca 900 ttccgcctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg gggcccgcac 960 aagcggtgga gcatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca 1020 tcttttgatc acctgagaga tcaggtttcc ccttcggggg caaaatgaca ggtggtgtat 1080 ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaaccctt 1140 atgactagtt gccagcattt agttgggcac tctagtaaga ctgccggtga caaaccggag 1200 gaaggtgggg atgacgtcaa atcatcatgc cccttatgac ctgggctaca cacgtgctac 1260 aatggatggt acaacgagtt gcgagaccgc gaggtcaagc taatctctta aagccattct 1320 cagttcggac tgtaggctgc aactcgccta cacgaagtcg gaatcgctag taatcgcgga 1380 tcagcacgcc gcggtgaata cgttcccggg ccttgtacac accgcccgtc acaccatgag 1440 agtttgtaac acccgaagcc ggtggcgtaa cccttttagg gagcgagccg tctaaggtgg 1500 gacaaatgat tagggtgaag tcgtaacaag gtagccgtag gagaacctgc ggctggatca 1560 cctcctt 1567 <210> 330 <211> 993 <212> DNA <213> Klebsiella oxytoca <400> 330 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtagc acagagagct tgctctcggg tgacgagtgg cggacgggtg agtaatgtct 120 gggaaactgc ccgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagaggggga ccttagggcc tcttgccatc ggatgtgccc agatgggatt 240 agcttgtagg tgaggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtatgaagaa ggccttcggg 420 ttgtaaagta ctttcagcgg ggaggaaggg agtgaggtta ataaccttat tcattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctgga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgctgtaa acgatgtcga cttggaggtt gttcccttga 840 ggagtggctt ccggagctaa cgcgttaagt cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tactcttgac atc 993 <210> 331 <211> 1510 <212> DNA <213> Clostridium perfringens <400> 331 attgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcttaaca catgcaagtc 60 gagcgatgaa gtttccttcg ggaaacggat tagcggcgga cgggtgagta acacgtgggt 120 aacctgcctc atagagtgga atagccttcc gaaaggaaga ttaataccgc ataatgttga 180 aagatggcat catcattcaa ccaaaggagc aatccgctat gagatggacc cgcggcgcat 240 tagctagttg gtggggtaac ggcctaccaa ggcgacgatg cgtagccgac ctgagagggt 300 gatcggccac attgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tgggggaaac cctgatgcag caacgccgcg tgagtgatga aggttttcgg 420 atcgtaaagc tctgtctttg gggaagataa tgacggtacc caaggaggaa gccacggcta 480 actacgtgcc agcagccgcg gtaatacgta ggtggcgagc gttatccgga tttactgggc 540 gtaaagggag cgtaggcgga tgattaagtg ggatgtgaaa tacccgggct caacttgggt 600 gctgcattcc aaactggtta tctagagtgc aggagaggag agtggaattc ctagtgtagc 660 ggtgaaatgc gtagagatta ggaagaacac cagtggcgaa ggcgactctc tggactgtaa 720 ctgacgctga ggctcgaaag cgtggggagc aaacaggatt agataccctg gtagtccacg 780 ccgtaaacga tgaatactag gtgtgggggt ttcaacacct ccgtgccgcc gctaacgcat 840 taagtattcc gcctggggag tacggtcgca agattaaaac tcaaaggaat tgacggggac 900 ccgcacaagt agcggagcat gtggtttaat tcgaagcaac gcgaagaacc ttacctacac 960 ttgacatccc ttgcattact cttaatcgag gaaatccctt cggggacaag gtgacaggtg 1020 gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca 1080 acccttgtcg ttagttacta ccattaagtt gaggactcta gcgagactgc ctgggttaac 1140 caggaggaag gtggggatga cgtcaaatca tcatgcccct tatgtgtagg gctacacacg 1200 tgctacaatg gctggtacag agagatgcaa taccgcgagg tggagccaaa cttaaaaacc 1260 agtctcagtt cggattgtag gctgaaactc gcctacatga agctggagtt actagtaatc 1320 gcgaatcaga atgtcgcggt gaatacgttc ccgggtcttg tacacaccgc ccgtcacacc 1380 atgagagttg gcaatacccg aagtccgtga gctaaccgca aggaggcagc ggccgaaggt 1440 agggtcagcg attggggtga agtcgtaaca aggtagccgt aggagaacct gcggctggat 1500 cacctccttt 1510 <210> 332 <211> 1543 <212> DNA <213> Streptococcus_mitis_oralis_pneumoniae <400> 332 taatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 agaacgctga aggaggagct tgcttctccg gatgagttgc gaacgggtga gtaacgcgta 120 ggtaacctgc ctggtagcgg gggataacta ttggaaacga tagctaatac cgcataacag 180 tagatgttgc atgacatttg cttaaaaggt gcaattgcat cactaccaga tggacctgcg 240 ttgtattagc tagttggtgg ggtaacggct caccaaggcg acgatacata gccgacctga 300 gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg aggcagcagt 360 agggaatctt cggcaatgga cggaagtctg accgagcaac gccgcgtgag tgaagaaggt 420 tttcggatcg taaagctctg ttgtaagaga agaacgagtg tgagagtgga aagttcacac 480 tgtgacggta tcttaccaga aagggacggc taactacgtg ccagcagccg cggtaatacg 540 taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg gttagataag 600 tctgaagtta aaggctgtgg cttaaccata gtacgctttg gaaactgttt aacttgagtg 660 caagagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata tggaggaaca 720 ccggtggcga aagcggctct ctggcttgta actgacgctg aggctcgaaa gcgtggggag 780 caaacaggat tagataccct ggtagtccac gccgtaaacg atgagtgcta ggtgttagac 840 cctttccggg gtttagtgcc gcagctaacg cattaagcac tccgcctggg gagtacgacc 900 gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag catgtggttt 960 aattcgaagc aacgcgaaga accttaccag gtcttgacat ccctctgacc gctctagaga 1020 tagagttttc cttcgggaca gaggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg 1080 tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg ccatcattta 1140 gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa 1200 tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggctggta caacgagtcg 1260 caagccggtg acggcaagct aatctcttaa agccagtctc agttcggatt gtaggctgca 1320 actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg cggtgaatac 1380 gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg 1440 gtgaggtaac cgtaaggagc cagccgccta aggtgggata gatgattggg gtgaagtcgt 1500 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctt 1543 <210> 333 <211> 1244 <212> DNA <213> Bacteroides ovatus <400> 333 cgatggatag gggttctgag aggaaggtcc cccacattgg aactgagaca cggtccaaac 60 tcctacggga ggcagcagtg aggaatattg gtcaatgggc gagagcctga accagccaag 120 tagcgtgaag gatgaaggct ctatgggtcg taaacttctt ttatatggga ataaagtttt 180 ccacgtgtgg aattttgtat gtaccatatg aataaggatc ggctaactcc gtgccagcag 240 ccgcggtaat acggaggatc cgagcgttat ccggatttat tgggtttaaa gggagcgtag 300 gtggattgtt aagtcagttg tgaaagtttg cggctcaacc gtaaaattgc agttgaaact 360 ggcagtcttg agtacagtag aggtgggcgg aattcgtggt gtagcggtga aatgcttaga 420 tatcacgaag aactccgatt gcgaaggcag ctcactagac tgtcactgac actgatgctc 480 gaaagtgtgg gtatcaaaca ggattagata ccctggtagt ccacacagta aacgatgaat 540 actcgctgtt tgcgatatac agtaagcggc caagcgaaag cattaagtat tccacctggg 600 gagtacgccg gcaacggtga aactcaaagg aattgacggg ggcccgcaca agcggaggaa 660 catgtggttt aattcgatga tacgcgagga accttacccg ggcttaaatt gcaacagaat 720 atattggaaa cagtatagcc gtaaggctgt tgtgaaggtg ctgcatggtt gtcgtcagct 780 cgtgccgtga ggtgtcggct taagtgccat aacgagcgca acccttatct ttagttacta 840 acaggtcatg ctgaggactc tagagagact gccgtcgtaa gatgtgagga aggtggggat 900 gacgtcaaat cagcacggcc ccttacgtcc ggggctacac acgtgttaca atggggggta 960 cagaaggcgg ctacctggtg acaggatgct aatcccaaaa acctctctca gttcggatcg 1020 aagtctgcaa cccgacttcg tgaagctgga ttcgctagta atcgcgcatc agccatggcg 1080 cggtgaatac gttcccgggc cttgtacaca ccgcccgtca agccatgaaa gccgggggta 1140 cctgaagtac gtaaccgcaa ggagcgtcct agggtaaaac tggtaattgg ggctaagtcg 1200 taacaaggta gccgtaccgg aaggtgcggc tggaacacct cctt 1244 <210> 334 <211> 1526 <212> DNA <213> Bacteroides ovatus <400> 334 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc attttagttt gcttgcaaac tgaagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactccgga atagcctttc gaaagaaaga ttaataccgg 180 atagcatacg aatatcgcat gatattttta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag tttgttggcg gggtaacggc ccaccaagac tacgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg gcgagagcct gaaccagcca agtagcgtga aggatgaagg 420 ctctatgggt cgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggattg ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgaaa ctggcagtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactag actgtcactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcaacaga atatattgga aacagtatag 1020 ccgtaaggct gttgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtta tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 ccccttacgt ccggggctac acacgtgtta caatgggggg tacagaaggc ggctacctgg 1260 tgacaggatg ctaatcccaa aaacctctct cagttcggat cgaagtctgc aacccgactt 1320 cgtgaagctg gattcgctag taatcgcgca tcagccatgg cgcggtgaat acgttcccgg 1380 gccttgtaca caccgcccgt caagccatga aagccggggg tacctgaagt acgtaaccgc 1440 aaggagcgtc ctagggtaaa actggtaatt ggggctaagt cgtaacaagg tagccgtacc 1500 ggaaggtgcg gctggaacac ctcctt 1526 <210> 335 <211> 1525 <212> DNA <213> Bacteroides ovatus <400> 335 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc attttagttt gcttgcaaac tgaagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactccgga atagcctttc gaaagaaaga ttaataccgg 180 atagcatacg aatatcgcat gatattttta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag tttgttggcg gggtaacggc ccaccaagac tacgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg gcgagagcct gaaccagcca agtagcgtga aggatgaagg 420 ctctatgggt cgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggattg ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgaaa ctggcagtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactag actgtcactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcaacaga atatattgga aacagtatag 1020 ccgtaaggct gttgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtta tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctacacggc 1260 gacgtgatgc taatcccaaa aacctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 336 <211> 1525 <212> DNA <213> Bacteroides ovatus <400> 336 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc attttagttt gcttgcaaac taaagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactcgggg atagcctttc gaaagaaaga ttaatatccg 180 atggtatatt ttctccgcat ggtgagaata ttaaagaatt tcggttatcg atggggatgc 240 gttccattag tttgttggcg gggtaacggc ccaccaagac cacgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg acgagagtct gaaccagcca agtagcgtga aggatgactg 420 ccctatgggt tgtaaacttc ttttatatgg gaataaagtg ttccacgtgt gggattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggattg ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgaaa ctggcagtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactag actgttactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcaacaga atatattgga aacagtatag 1020 ccgtaaggct gttgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtca tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggcg gctacctggt 1260 gacaggatgc taatcccaaa aacctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 337 <211> 1202 <212> DNA <213> Bacteroides uniformis <400> 337 actgagacac ggtccaaact cctacgggag gcagcagtga ggaatattgg tcaatggacg 60 agagtctgaa ccagccaagt agcgtgaagg atgactgccc tatgggttgt aaacttcttt 120 tatacgggaa taaagtgagg cacgtgtgcc tttttgtatg taccgtatga ataaggatcg 180 gctaactccg tgccagcagc cgcggtaata cggaggatcc gagcgttatc cggatttatt 240 gggtttaaag ggagcgtagg cggacgctta agtcagttgt gaaagtttgc ggctcaaccg 300 taaaattgca gttgatactg ggtgtcttga gtacagtaga ggcaggcgga attcgtggtg 360 tagcggtgaa atgcttagat atcacgaaga actccgattg cgaaggcagc ttgctggact 420 gtaactgacg ctgatgctcg aaagtgtggg tatcaaacag gattagatac cctggtagtc 480 cacacagtaa acgatgaata ctcgctgttt gcgatataca gtaagcggcc aagcgaaagc 540 gttaagtatt ccacctgggg agtacgccgg caacggtgaa actcaaagga attgacgggg 600 gcccgcacaa gcggaggaac atgtggttta attcgatgat acgcgaggaa ccttacccgg 660 gcttgaattg caactgaatg atgtggagac atgtcagccg caaggcagtt gtgaaggtgc 720 tgcatggttg tcgtcagctc gtgccgtgag gtgtcggctt aagtgccata acgagcgcaa 780 cccttatcga tagttaccat caggttatgc tggggactct gtcgagactg ccgtcgtaag 840 atgtgaggaa ggtggggatg acgtcaaatc agcacggccc ttacgtccgg ggctacacac 900 gtgttacaat ggggggtaca gaaggcagct acacggcgac gtgatgctaa tcccgaaagc 960 ctctctcagt tcggattgga gtctgcaacc cgactccatg aagctggatt cgctagtaat 1020 cgcgcatcag ccacggcgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaag 1080 ccatgaaagc cgggggtacc tgaagtgcgt aaccgcaagg agcgccctag ggtaaaactg 1140 gtgattgggg ctaagtcgta acaaggtagc cgtaccggaa ggtgcggctg gaacacctcc 1200 tt 1202 <210> 338 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 338 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tggaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 339 <211> 1202 <212> DNA <213> Bacteroides uniformis <400> 339 actgagacac ggtccaaact cctacgggag gcagcagtga ggaatattgg tcaatggacg 60 agagtctgaa ccagccaagt agcgtgaagg atgactgccc tatgggttgt aaacttcttt 120 tatacgggaa taaagtgagg cacgtgtgcc tttttgtatg taccgtatga ataaggatcg 180 gctaactccg tgccagcagc cgcggtaata cggaggatcc gagcgttatc cggatttatt 240 gggtttaaag ggagcgtagg cggacgctta agtcagttgt gaaagtttgc ggctcaaccg 300 taaaattgca gttgatactg ggtgtcttga gtacagtaga ggcaggcgga attcgtggtg 360 tagcggtgaa atgcttagat atcacgaaga actccgattg cgaaggcagc ttgctggact 420 gtaactgacg ctgatgctcg aaagtgtggg tatcaaacag gattagatac cctggtagtc 480 cacacagtaa acgatgaata ctcgctgttt gcgatataca gtaagcggcc aagcgaaagc 540 gttaagtatt ccacctgggg agtacgccgg caacggtgaa actcaaagga attgacgggg 600 gcccgcacaa gcggaggaac atgtggttta attcgatgat acgcgaggaa ccttacccgg 660 gcttgaattg caactgaatg atgtggagac atgtcagccg caaggcagtt gtgaaggtgc 720 tgcatggttg tcgtcagctc gtgccgtgag gtgtcggctt aagtgccata acgagcgcaa 780 cccttatcga tagttaccat caggttatgc tggggactct gtcgagactg ccgtcgtaag 840 atgtgaggaa ggtggggatg acgtcaaatc agcacggccc ttacgtccgg ggctacacac 900 gtgttacaat ggggggtaca gaaggcagct acacggcgac gtgatgctaa tcccgaaagc 960 ctctctcagt tcggattgga gtctgcaacc cgactccatg aagctggatt cgctagtaat 1020 cgcgcatcag ccacggcgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaag 1080 ccatgaaagc cgggggtacc tgaagtgcgt aaccgcaagg agcgccctag ggtaaaactg 1140 gtgattgggg ctaagtcgta acaaggtagc cgtaccggaa ggtgcggctg gaacacctcc 1200 tt 1202 <210> 340 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 340 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 341 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 341 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tggaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 342 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 342 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 343 <211> 1523 <212> DNA <213> Bacteroides uniformis <400> 343 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atgaacttag cttgctaagt ttgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgatg actcggggat agcctttcga aagaaagatt aatacccgat 180 ggcatagttc ttccgcatgg tagaactatt aaagaatttc ggtcatcgat ggggatgcgt 240 tccattaggt tgttggcggg gtaacggccc accaagcctt cgatggatag gggttctgag 300 aggaaggtcc cccacattgg aactgagaca cggtccaaac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gagagtctga accagccaag tagcgtgaag gatgactgcc 420 ctatgggttg taaacttctt ttatacggga ataaagtgag gcacgtgtgc ctttttgtat 480 gtaccgtatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatc 540 cgagcgttat ccggatttat tgggtttaaa gggagcgtag gcggacgctt aagtcagttg 600 tgaaagtttg cggctcaacc gtaaaattgc agttgatact gggtgtcttg agtacagtag 660 aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag aactccgatt 720 gcgaaggcag cttgctggac tgtaactgac gctgatgctc gaaagtgtgg gtatcaaaca 780 ggattagata ccctggtagt ccacacagta aacgatgaat actcgctgtt tgcgatatac 840 agtaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg gcaacggtga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaatt gcaactgaat gatgtggaga catgtcagcc 1020 gcaaggcagt tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga ggtgtcggct 1080 taagtgccat aacgagcgca acccttatcg atagttacca tcaggttatg ctggggactc 1140 tgtcgagact gccgtcgtaa gatgtgagga aggtggggat gacgtcaaat cagcacggcc 1200 cttacgtccg gggctacaca cgtgttacaa tggggggtac agaaggcagc tacacggcga 1260 cgtgatgcta atcccgaaag cctctctcag ttcggattgg agtctgcaac ccgactccat 1320 gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg ttcccgggcc 1380 ttgtacacac cgcccgtcaa gccatgaaag ccgggggtac ctgaagtgcg taaccgcaag 1440 gagcgcccta gggtaaaact ggtgattggg gctaagtcgt aacaaggtag ccgtaccgga 1500 aggtgcggct ggaacacctc ctt 1523 <210> 344 <211> 1051 <212> DNA <213> Bacteroides vulgatus <400> 344 tttgcatgta ctttatgaat aaggatcggc taactccgtg ccagcagccg cggtaatacg 60 gaggatccga gcgttatccg gatttattgg gtttaaaggg agcgtagatg gatgtttaag 120 tcagttgtga aagtttgcgg ctcaaccgta aaattgcagt tgatactgga tatcttgagt 180 gcagttgagg caggcggaat tcgtggtgta gcggtgaaat gcttagatat cacgaagaac 240 tccgattgcg aaggcagcct gctaagctgc aactgacatt gaggctcgaa agtgtgggta 300 tcaaacagga ttagataccc tggtagtcca cacggtaaac gatgaatact cgctgtttgc 360 gatatacggc aagcggccaa gcgaaagcgt taagtattcc acctggggag tacgccggca 420 acggtgaaac tcaaaggaat tgacgggggc ccgcacaagc ggaggaacat gtggtttaat 480 tcgatgatac gcgaggaacc ttacccgggc ttaaattgca gatgaattac ggtgaaagcc 540 gtaagccgca aggcatctgt gaaggtgctg catggttgtc gtcagctcgt gccgtgaggt 600 gtcggcttaa gtgccataac gagcgcaacc cttgttgtca gttactaaca ggttctgctg 660 aggactctga caagactgcc atcgtaagat gtgaggaagg tggggatgac gtcaaatcag 720 cacggccctt acgtccgggg ctacacacgt gttacaatgg ggggtacaga gggccgctac 780 cacgcgagtg gatgccaatc ccaaaaacct ctctcagttc ggactggagt ctgcaacccg 840 actccacgaa gctggattcg ctagtaatcg cgcatcagcc acggcgcggt gaatacgttc 900 ccgggccttg tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtgcgtaa 960 ccgcgaggag cgccctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg 1020 taccggaagg tgcggctgga acacctcctt t 1051 <210> 345 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 345 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gttcacatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatggata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cggcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 346 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 346 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtaggcga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatgtata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 347 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 347 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgcaggcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatgcata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttcc gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggtcg ctaccacgcg 1260 agtggatgcc aatccccaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 348 <211> 1524 <212> DNA <213> Bacteroides vulgatus <400> 348 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atggtcttag cttgctaagg ccgatggcga ccggcgcacg ggtgagtaac 120 acgtatccaa cctgccgtct actcttggac agccttctga aaggaagatt aatacaagat 180 ggcatcatga gtccgcatgt tcacatgatt aaaggtattc cggtagacga tggggatgcg 240 ttccattaga tagtaggcgg ggtaacggcc cacctagtct tcgatggata ggggttctga 300 gaggaaggtc ccccacattg gaactgagac acggtccaaa ctcctacggg aggcagcagt 360 gaggaatatt ggtcaatggg cgagagcctg aaccagccaa gtagcgtgaa ggatgactgc 420 cctatgggtt gtaaacttct tttataaagg aataaagtcg ggtatggata cccgtttgca 480 tgtactttat gaataaggat cggctaactc cgtgccagca gccgcggtaa tacggaggat 540 ccgagcgtta tccggattta ttgggtttaa agggagcgta gatggatgtt taagtcagtt 600 gtgaaagttt gcggctcaac cgtaaaattg cagttgatac tggatatctt gagtgcagtt 660 gaggcaggcg gaattcgtgg tgtagcggtg aaatgcttag atatcacgaa gaactccgat 720 tgcgaaggca gcctgctaag ctgcaactga cattgaggct cgaaagtgtg ggtatcaaac 780 aggattagat accctggtag tccacacggt aaacgatgaa tactcgctgt ttgcgatata 840 cagcaagcgg ccaagcgaaa gcgttaagta ttccacctgg ggagtacgcc ggcaacggtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggagga acatgtggtt taattcgatg 960 atacgcgagg aaccttaccc gggcttaaat tgcagatgaa ttacggtgaa agccgtaagc 1020 cgcaaggcat ctgtgaaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggc 1080 ttaagtgcca taacgagcgc aacccttgtt gtcagttact aacaggttct gctgaggact 1140 ctgacaagac tgccatcgta agatgtgagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggggggta cagagggccg ctaccacgcg 1260 agtggatgcc aatcccaaaa acctctctca gttcggactg gagtctgcaa cccgactcca 1320 cgaagctgga ttcgctagta atcgcgcatc agccacggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggga gccgggggta cctgaagtgc gtaaccgcga 1440 ggagcgccct agggtaaaac tggtgactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct cctt 1524 <210> 349 <211> 1054 <212> DNA <213> Bacteroides vulgatus <400> 349 ccgtttgcat gtactttatg aataaggatc ggctaactcc gtgccagcag ccgcggtaat 60 acggaggatc cgagcgttat ccggatttat tgggtttaaa gggagcgtag atggatgttt 120 aagtcagttg tgaaagtttg cggctcaacc gtaaaattgc agttgatact ggatatcttg 180 agtgcagttg aggcaggcgg aattcgtggt gtagcggtga aatgcttaga tatcacgaag 240 aactccgatt gcgaaggcag cctgctaagc tgcaactgac attgaggctc gaaagtgtgg 300 gtatcaaaca ggattagata ccctggtagt ccacacggta aacgatgaat actcgctgtt 360 tgcgatatac agcaagcggc caagcgaaag cgttaagtat tccacctggg gagtacgccg 420 gcaacggtga aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt 480 aattcgatga tacgcgagga accttacccg ggcttaaatt gcagatgaat tacggtgaaa 540 gccgtaagcc gcaaggcatc tgtgaaggtg ctgcatggtt gtcgtcagct cgtgccgtga 600 ggtgtcggct taagtgccat aacgagcgca acccttgttg tcagttacta acaggttctg 660 ctgaggactc tgacaagact gccatcgtaa gatgtgagga aggtggggat gacgtcaaat 720 cagcacggcc cttacgtccg gggctacaca cgtgttacaa tggggggtac agagggccgc 780 taccacgcga gtggatgcca atccccaaaa cctctctcag ttcggactgg agtctgcaac 840 ccgactccac gaagctggat tcgctagtaa tcgcgcatca gccacggcgc ggtgaatacg 900 ttcccgggcc ttgtacacac cgcccgtcaa gccatgggag ccgggggtac ctgaagtgcg 960 taaccgcgag gagcgcccta gggtaaaact ggtgactggg gctaagtcgt aacaaggtag 1020 ccgtaccgga aggtgcggct ggaacacctc cttt 1054 <210> 350 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 350 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 351 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 351 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 352 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 352 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccatatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtgaagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 353 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 353 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccacatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta agttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 354 <211> 1535 <212> DNA <213> Eubacterium_sp_3_1_31 <400> 354 atggagagtt tgatcctggc tcaggatgaa cgctggcggc atgcctaata catgcaagtc 60 gaacgaagtc tttaggaagc ttgcttccaa agagacttag tggcgaacgg gtgagtaaca 120 cgtaggtaac ctgcccatgt gcccgggata actgctggaa acggtagcta aaaccggata 180 ggtatgaggg aggcatcttc ctcatattaa agcaccttcg ggtgtgaaca tggatggacc 240 tgcggcgcat tagctggttg gtgaggtaac ggcccaccaa ggcgatgatg cgtagccgac 300 ctgagagggt gaacggccac attgggactg agacacggcc caaactccta cgggaggcag 360 cagtagggaa ttttcgtcaa tggggggaac cctgaacgag caatgccgcg tgtgtgaaga 420 aggtcttcgg atcgtaaagc actgttgtaa gtgaagaatg ccatatagag gaaatgctat 480 gtgggtgacg gtagcttacc agaaagccac ggctaactac gtgccagcag ccgcggtaat 540 acgtaggtgg caagcgttat ccggaatcat tgggcgtaaa gggtgcgtag gtggcacgat 600 aagtctgaag taaaaggcaa cagctcaact gttgtatgct ttggaaactg tcgagctaga 660 gtgcagaaga gggcgatgga attccatgtg tagcggtaaa atgcgtagat atatggagga 720 acaccagtgg cgaaggcggt cgcctggtct gtaactgaca ctgatgcacg aaagcgtggg 780 gagcaaatag gattagatac cctagtagtc cacgccgtaa acgatgagaa ctaagtgttg 840 gagagattca gtgctgcagt taacgcaata agttctccgc ctggggagta tgcacgcaag 900 tgtgaaactc aaaggaattg acgggggccc gcacaagcgg tggagtatgt ggtttaattc 960 gaagcaacgc gaagaacctt accaggcctt gacatggata taaatgttct agagatagaa 1020 agatagctat atatcacaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt gtcttctgtt accagcatta ggttggggac 1140 tcaggagaga ctgccggtga caaaccggag gaaggtgggg atgacgtcaa atcatcatgc 1200 cccttatggc ctgggctaca cacgtactac aatggcgcct acaaagagca gcgacaccgc 1260 gaggtggagc gaatctcata aagggcgtct cagttcggat tgaagtctgc aactcgactt 1320 catgaagtcg gaatcgctag taatcgcaga tcagcatgct gcggtgaata cgttctcggg 1380 ccttgtacac accgcccgtc aaaccatggg agttggtaat acccgaagcc ggtggcataa 1440 ccgcaaggag tgagccgtcg aaggtaggac cgatgactgg ggttaagtcg taacaaggta 1500 tccctacggg aacgtgggga tggatcacct ccttt 1535 <210> 355 <211> 1398 <212> DNA <213> Morganella morganii <400> 355 ggggataact actggaaacg gtagctaata ccgcataatg tcttcggacc aaagcggggg 60 acctccgggc ctcgcgccat cagatgaacc catatgggat tagctagtag gtgaggtaac 120 ggcttaccta ggcgacgatc cctagctggt ctgagaggat gatcagccac actgggactg 180 agacacggcc cagactccta cgggaggcag cagtggggaa tattgcacaa tgggcgcaag 240 cctgatgcag ccatgccgcg tgtatgaaga aggccttcgg gttgtaaagt actttcagtc 300 gggaggaagg tgtcaaggtt aataaccttg gcaattgacg ttaccgacag aagaagcacc 360 ggctaactcc gtgccagcag ccgcggtaat acggagggtg caagcgttaa tcggaattac 420 tgggcgtaaa gcgcacgcag gcggttgatt gagtcagatg tgaaatcccc gggcttaacc 480 cgggaattgc atctgatact ggtcagctag agtcttgtag aggggggtag aattccatgt 540 gtagcggtga aatgcgtaga gatgtggagg aataccggtg gcgaaggcgg ccccctggac 600 aaagactgac gctcaggtgc gaaagcgtgg ggagcaaaca ggattagata ccctggtagt 660 ccacgctgta aacgatgtcg acttggaggt tgtgcccttg aggcgtggct tccggagcta 720 acgcgttaag tcgaccgcct ggggagtacg gccgcaaggt taaaactcaa atgaattgac 780 gggggcccgc acaagcggtg gagcatgtgg tttaattcga tgcaacgcga agaaccttac 840 ctactcttga catccagaga acttagcaga gatgctttgg tgccttcggg aactctgaga 900 caggtgctgc atggctgtcg tcagctcgtg ttgtgaaatg ttgggttaag tcccgcaacg 960 agcgcaaccc ttatcctttg ttgccagcgc gtgatggcgg gaactcaaag gagactgccg 1020 gtgataaacc ggaggaaggt ggggatgacg tcaagtcatc atggccctta cgagtagggc 1080 tacacacgtg ctacaatggc gtatacaaag ggaagcgacc ccgcgagggc aagcggaact 1140 cataaagtac gtcgtagtcc ggattggagt ctgcaactcg actccatgaa gtcggaatcg 1200 ctagtaatcg tagatcagaa tgctacggtg aatacgttcc cgggccttgt acacaccgcc 1260 cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc ttaacctccg ggagggcgct 1320 taccactttg tgattcatga ctggggtgaa gtcgtaacaa ggtaaccgta ggggaacctg 1380 cggttggatc acctcctt 1398 <210> 356 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 356 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgtaag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaggccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 357 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 357 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttgcct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggccccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggatgccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgaaaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 358 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 358 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtgatgctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaagccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgaaaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 359 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 359 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagcg ggggtagcaa tacccgccgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggccccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgcgag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaatgctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaggccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 360 <211> 1521 <212> DNA <213> Parabacteroides_distasonis <400> 360 cgaagagttt gatcctggct caggatgaac gctagcgaca ggcttaacac atgcaagtcg 60 aggggcagca caggtagcaa taccgggtgg cgaccggcgc acgggtgagt aacgcgtatg 120 caacttacct atcagagggg gataacccgg cgaaagtcgg actaataccg catgaagcag 180 gggtcccgca tggggatatt tgctaaagat tcatcgctga tagataggca tgcgttccat 240 taggcagttg gcggggtaac ggcccaccaa accgacgatg gataggggtt ctgagaggaa 300 ggtcccccac attggtactg agacacggac caaactccta cgggaggcag cagtgaggaa 360 tattggtcaa tgggcgtaag cctgaaccag ccaagtcgcg tgagggatga aggttctatg 420 gatcgtaaac ctcttttata agggaataaa gtgcgggacg tgtcctgttt tgtatgtacc 480 ttatgaataa ggatcggcta actccgtgcc agcagccgcg gtaatacgga ggatccgagc 540 gttatccgga tttattgggt ttaaagggtg cgtaggcggc cttttaagtc agcggtgaaa 600 gtctgtggct caaccataga attgccgttg aaactggggg gcttgagtat gtttgaggca 660 ggcggaatgc gtggtgtagc ggtgaaatgc ttagatatca cgcagaaccc cgattgcgaa 720 ggcagcctgc caagccatga ctgacgctga tgcacgaaag cgtggggatc aaacaggatt 780 agataccctg gtagtccacg cagtaaacga tgatcactag ctgtttgcga tacagtgtaa 840 gcggcacagc gaaagcgtta agtgatccac ctggggagta cgccggcaac ggtgaaactc 900 aaaggaattg acgggggccc gcacaagcgg aggaacatgt ggtttaattc gatgatacgc 960 gaggaacctt acccgggttt gaacgcattc ggaccgaggt ggaaacacct tttctagcaa 1020 tagccgtttg cgaggtgctg catggttgtc gtcagctcgt gccgtgaggt gtcggcttaa 1080 gtgccataac gagcgcaacc cttgccacta gttactaaca ggtaaagctg aggactctgg 1140 tgggactgcc agcgtaagct gcgaggaagg cggggatgac gtcaaatcag cacggccctt 1200 acatccgggg cgacacacgt gttacaatgg cgtggacaaa gggaagccac ctggcgacag 1260 ggagcgaatc cccaaaccac gtctcagttc ggatcggagt ctgcaacccg actccgtgaa 1320 gctggattcg ctagtaatcg cgcatcagcc atggcgcggt gaatacgttc ccgggccttg 1380 tacacaccgc ccgtcaagcc atgggagccg ggggtacctg aagtccgtaa ccgcgaggat 1440 cggcctaggg taaaactggt gactggggct aagtcgtaac aaggtagccg taccggaagg 1500 tgcggctgga acacctcctt t 1521 <210> 361 <211> 1535 <212> DNA <213> Citrobacter freundii <400> 361 attggagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 cgagcgagtc ccttcggggg ctagcggcgg acgggtgagt aacacgtagg caacctgcct 120 ctcagactgg gataacatag ggaaacttat gctaataccg gataggtttt tggatcgcat 180 gatctgaaaa gaaaagatgg cttttcgcta tcactgggag atgggcctgc ggcgcattag 240 ctagttggtg gggtaacggc ctaccaaggc gacgatgcgt agccgacctg agagggtgac 300 cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag tagggaattt 360 tccacaatgg acgaaagtct gatggagcaa cgccgcgtga acgatgaagg tcttcggatt 420 gtaaagttct gttgtcaggg acgaacacgt accgttcgaa tagggcggta ccttgacggt 480 acctgacgag aaagccacgg ctaactacgt gccagcagcc gcggtaatac gtaggtggca 540 agcgttgtcc ggatttattg ggcgtaaagc gcgcgcaggc ggctatgtaa gtctggtgtt 600 aaagcccggg gctcaacccc ggttcgcatc ggaaactgtg tagcttgagt gcagaagagg 660 aaagcggtat tccacgtgta gcggtgaaat gcgtagagat gtggaggaac accagtggcg 720 aaggcggctt tctggtctgt aactgacgct gaggcgcgaa agcgtgggga gcaaacagga 780 ttagataccc tggtagtcca cgccgtaaac gatgagtgct aggtgttggg ggtttcaata 840 ccctcagtgc cgcagctaac gcaataagca ctccgcctgg ggagtacgct cgcaagagtg 900 aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt taattcgaag 960 caacgcgaag aaccttacca ggtcttgaca tcccgctgac cgctctggag acagagcttc 1020 ccttcggggc agcggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt 1080 gggttaagtc ccgcaacgag cgcaaccctt atctttagtt gccagcattc agttgggcac 1140 tctagagaga ctgccgtcga caagacggag gaaggcgggg atgacgtcaa atcatcatgc 1200 cccttatgac ctgggctaca cacgtgctac aatggttggt acaacgggac gctacctcgc 1260 gagaggacgc caatctctta aaaccaatct cagttcggat tgtaggctgc aactcgccta 1320 catgaagtcg gaatcgctag taatcgcgga tcagcatgcc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc acaccacggg agtttgcaac acccgaagtc ggtgaggtaa 1440 ccgcaaggag ccagccgccg aaggtggggt agatgactgg ggtgaagtcg taacaaggta 1500 tccgtaccgg aaggtgcgga tggatcacct ccttt 1535 <210> 362 <211> 1538 <212> DNA <213> Citrobacter freundii <400> 362 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtagc acagaggagc ttgctccttg ggtgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcccgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa cggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc gaggaggaag gcgttgtggt taataaccgc agcgattgac 480 gttactcgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtctgt caagtcggat 600 gtgaaatccc cgggctcaac ctgggaactg catccgaaac tggcaggcta gagtcttgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctactcttg acatccagag aacttagcag agatgctttg 1020 gtgccttcgg gaactctgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gttcggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgagtagggc tacacacgtg ctacaatggc atatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtat gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 363 <211> 1544 <212> DNA <213> Lactococcus lactis <400> 363 atttgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 tgagcgctga aggttggtac ttgtaccgac tggatgagca gcgaacgggt gagtaacgcg 120 tggggaatct gcctttgagc gggggacaac atttggaaac gaatgctaat accgcataaa 180 aactttaaac acaagtttta agtttgaaag atgcaattgc atcactcaaa gatgatcccg 240 cgttgtatta gctagttggt gaggtaaagg ctcaccaagg cgatgataca tagccgacct 300 gagagggtga tcggccacat tgggactgag acacggccca aactcctacg ggaggcagca 360 gtagggaatc ttcggcaatg gacgaaagtc tgaccgagca acgccgcgtg agtgaagaag 420 gttttcggat cgtaaaactc tgttggtaga gaagaacgtt ggtgagagtg gaaagctcat 480 caagtgacgg taactaccca gaaagggacg gctaactacg tgccagcagc cgcggtaata 540 cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg tggtttatta 600 agtctggtgt aaaaggcagt ggctcaacca ttgtatgcat tggaaactgg tagacttgag 660 tgcaggagag gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa 720 caccggtggc gaaagcggct ctctggcctg taactgacac tgaggctcga aagcgtgggg 780 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc tagatgtagg 840 gagctataag ttctctgtat cgcagctaac gcaataagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tactcgtgct attcctagag 1020 ataggaagtt ccttcgggac acgggataca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcatta 1140 agttgggcac tctaacgaga ctgccggtga taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggatggt acaacgagtc 1260 gcgagacagt gatgtttagc taatctctta aaaccattct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacggg agttgggagt acccgaagta 1440 ggttgcctaa ccgcaaggag ggcgcttcct aaggtaagac cgatgactgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 364 <211> 1544 <212> DNA <213> Lactococcus lactis <400> 364 atttgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt 60 tgagcgctga aggttggtac ttgtaccgac tggatgagca gcgaacgggt gagtaacgcg 120 tggggaatct gcctttgagc gggggacaac atttggaaac gaatgctaat accgcataaa 180 aactttaaac acaagtttta agtttgaaag atgcaattgc atcactcaaa gatgatcccg 240 cgttgtatta gctagttggt gaggtaaagg ctcaccaagg cgatgataca tagccgacct 300 gagagggtga tcggccacat tgggactgag acacggccca aactcctacg ggaggcagca 360 gtagggaatc ttcggcaatg gacgaaagtc tgaccgagca acgccgcgtg agtgaagaag 420 gttttcggat cgtaaaactc tgttggtaga gaagaacgtt ggtgagagtg gaaagctcat 480 caagtgacgg taactaccca gaaagggacg gctaactacg tgccagcagc cgcggtaata 540 cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg tggtttatta 600 agtctggtgt aaaaggcagt ggctcaacca ttgtatgcat tggaaactgg tagacttgag 660 tgcaggagag gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa 720 caccggtggc gaaagcggct ctctggcctg taactgacac tgaggctcga aagcgtgggg 780 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc tagatgtagg 840 gagctataag ttctctgtat cgcagctaac gcaataagca ctccgcctgg ggagtacgac 900 cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt 960 taattcgaag caacgcgaag aaccttacca ggtcttgaca tactcgtgct attcctagag 1020 ataggaagtt ccttcgggac acgggataca ggtggtgcat ggttgtcgtc agctcgtgtc 1080 gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcatta 1140 agttgggcac tctaacgaga ctgccggtga taaaccggag gaaggtgggg atgacgtcaa 1200 atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggatggt acaacgagtc 1260 gcgagacagt gatgtttagc taatctctta aaaccattct cagttcggat tgtaggctgc 1320 aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata 1380 cgttcccggg ccttgtacac accgcccgtc acaccacggg agttgggagt acccgaagta 1440 ggttgcctaa ccgcaaggag ggcgcttcct aaggtaagac cgatgactgg ggtgaagtcg 1500 taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctt 1544 <210> 365 <211> 1525 <212> DNA <213> Alistipes_onderdonkii <400> 365 atggagagtt tgatcctggc tcaggatgaa cgctagcggc aggcctaaca catgcaagtc 60 gaggggcatc gggattgaag cttgcttcaa ttgccggcga ccggcgcacg ggtgcgtaac 120 gcgtatgtaa cctacctata acaggggcat aacactgaga aattggtact aattccccat 180 aatattcgga gaggcatctc tccgggttga aaactccggt ggttatagat ggacatgcgt 240 tgtattagct agttggtgag gtaacggctc accaaggcaa cgatacatag ggggactgag 300 aggttaaccc cccacactgg tactgagaca cggaccagac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gcaagtctga accagccatg ccgcgtgcag gaagacggct 420 ctatgagttg taaactgctt ttgtacgagg gtaaactcac ctacgtgtag gtgactgaaa 480 gtatcgtacg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatt 540 caagcgttat ccggatttat tgggtttaaa gggtgcgtag gcggtttgat aagttagagg 600 tgaaatcccg gggcttaact ccggaactgc ctctaatact gttagactag agagtagttg 660 cggtaggcgg aatgtatggt gtagcggtga aatgcttaga gatcatacag aacaccgatt 720 gcgaaggcag cttaccaaac tatatctgac gttgaggcac gaaagcgtgg ggagcaaaca 780 ggattagata ccctggtagt ccacgcagta aacgatgata actcgttgtc ggcgatacac 840 agtcggtgac taagcgaaag cgataagtta tccacctggg gagtacgttc gcaagaatga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaaag ttactgacga ttctggaaac aggatttccc 1020 ttcggggcag gaaactaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggg 1080 ttaagtccca taacgagcgc aacccctacc gttagttgcc atcaggtcaa gctgggcact 1140 ctggcgggac tgccggtgta agccgagagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggtaggta cagagggtcg ctaccccgcg 1260 aggggatgcc aatctcgaaa gcctatctca gttcggattg gaggctgaaa cccgcctcca 1320 tgaagttgga ttcgctagta atcgcgcatc agccatggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggaa gctgggggtg cctgaagttc gtgaccgcaa 1440 ggagcgacct agggcaaaac cggtaactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct ccttt 1525 <210> 366 <211> 1525 <212> DNA <213> Alistipes_onderdonkii <400> 366 atggagagtt tgatcctggc tcaggatgaa cgctagcggc aggcctaaca catgcaagtc 60 gaggggcatc gggattgaag cttgcttcaa ttgccggcga ccggcgcacg ggtgcgtaac 120 gcgtatgtaa cctacctata acaggggcat aacactgaga aattggtact aattccccat 180 aatattcgga gaggcatctc tccgggttga aaactccggt ggttatagat ggacatgcgt 240 tgtattagct agttggtgag gtaacggctc accaaggcaa cgatacatag ggggactgag 300 aggttaaccc cccacactgg tactgagaca cggaccagac tcctacggga ggcagcagtg 360 aggaatattg gtcaatggac gcaagtctga accagccatg ccgcgtgcag gaagacggct 420 ctatgagttg taaactgctt ttgtacgagg gtaaactcac ctacgtgtag gtgactgaaa 480 gtatcgtacg aataaggatc ggctaactcc gtgccagcag ccgcggtaat acggaggatt 540 caagcgttat ccggatttat tgggtttaaa gggtgcgtag gcggtttgat aagttagagg 600 tgaaatcccg gggcttaact ccggaactgc ctctaatact gttagactag agagtagttg 660 cggtaggcgg aatgtatggt gtagcggtga aatgcttaga gatcatacag aacaccgatt 720 gcgaaggcag cttaccaaac tatatctgac gttgaggcac gaaagcgtgg ggagcaaaca 780 ggattagata ccctggtagt ccacgcagta aacgatgata actcgttgtc ggcgatacac 840 agtcggtgac taagcgaaag cgataagtta tccacctggg gagtacgttc gcaagaatga 900 aactcaaagg aattgacggg ggcccgcaca agcggaggaa catgtggttt aattcgatga 960 tacgcgagga accttacccg ggcttgaaag ttactgacga ttctggaaac aggatttccc 1020 ttcggggcag gaaactaggt gctgcatggt tgtcgtcagc tcgtgccgtg aggtgtcggg 1080 ttaagtccca taacgagcgc aacccctacc gttagttgcc atcaggtcaa gctgggcact 1140 ctggcgggac tgccggtgta agccgagagg aaggtgggga tgacgtcaaa tcagcacggc 1200 ccttacgtcc ggggctacac acgtgttaca atggtaggta cagagggtcg ctaccccgcg 1260 aggggatgcc aatctcgaaa gcctatctca gttcggattg gaggctgaaa cccgcctcca 1320 tgaagttgga ttcgctagta atcgcgcatc agccatggcg cggtgaatac gttcccgggc 1380 cttgtacaca ccgcccgtca agccatggaa gctgggggtg cctgaagttc gtgaccgcaa 1440 ggagcgacct agggcaaaac cggtaactgg ggctaagtcg taacaaggta gccgtaccgg 1500 aaggtgcggc tggaacacct ccttt 1525 <210> 367 <211> 1647 <212> DNA <213> Campylobacter curvus <400> 367 atggagagtt tgatcctggc tcagagtgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacggacaa gtaagagctt gctcttatga gttagtggcg cacgggtgag taatgtatag 120 ctaatctgcc ccatagtgga ggacaacagt tggaaacgac tgctaatact ccatactcca 180 tttatatata agtataaatg ggaaagtcga accctatata ttgtttattt atcaaatacc 240 tacggcgcaa ccgaaagttg cggtgtgctt taggtgggtc aagggagcgt agctccttgt 300 cgcaaagacg gactttgttc gtctgcgaag taaataatat atagggtttc tcgctatggg 360 atgaggctat atcgtatcag ctagttggta aggtaatggc ttaccaaggc tatgacgcgt 420 aactggtctg agaggatgat cagtcacact ggaactgaga cacggtccag actcctacgg 480 gaggcagcag tagggaatat tgctcaatgg gggaaaccct gaagcagcaa cgccgcgtgg 540 aggatgacac ttttcggagc gtaaactcct tttcttgggg aagaaatttg acggtaccca 600 aggaataagc accggctaac tccgtgccag cagccgcggt aatacggagg gtgcaagcgt 660 tactcggaat cactgggcgt aaaggacgcg taggcggatt atcaagtctc ttgtgaaatc 720 caatggctta accattgaac tgcttgagaa actgataatc tagagtgagg gagaggtaga 780 tggaattggt ggtgtagggg taaaatccgt agagatcacc aggaataccc attgcgaagg 840 cgatctgctg gaactcaact gacgctaatg cgtgaaagcg tggggagcaa acaggattag 900 ataccctggt agtccacgcc ctaaacgatg tatactagtt gttgctgagc tagtcttggc 960 agtaatgcac ctaacggatt aagtataccg cctggggagt acggtcgcaa gattaaaact 1020 caaaggaata gacggggacc cgcacaagcg gtggagcatg tggtttaatt cgaagatacg 1080 cgaagaacct tacccggact tgatatctaa caaatcatct agagatagaa gagtgtctgc 1140 ttgcagaaat gttaagacag gtgctgcacg gctgtcgtca gctcgtgtcg tgagatgttg 1200 ggttaagtcc cgcaacgagc gcaacccacg tcattagttg ctaacggttc ggccgagcac 1260 tctaatgaga ctgccttcgc aaggaggagg aaggtgtgga cgacgtcaag tcatcatggc 1320 ccttatgtcc ggggcgacac acgtgctaca atggcgtata caatgagacg caatatcgcg 1380 agatggagca aatctataaa atacgtccca gttcggattg gagtctgcaa ctcgactcca 1440 tgaagccgga atcgctagta atcgtagatc agccatgcta cggtgaatac gttcccgggt 1500 cttgtactca ccgcccgtca caccatggga gttgatttca ctcgaagccc aaataccaaa 1560 ccggttatgg tccacagtgg aatcagcgac tggggtgaag tcgtaacaag gtaaccgtag 1620 gagaacctgc ggttggatca cctcctt 1647 <210> 368 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 368 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccgattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 369 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 369 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgacggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 370 <211> 1573 <212> DNA <213> Lactobacillus fermentum <400> 370 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taacggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc ttt 1573 <210> 371 <211> 1572 <212> DNA <213> Lactobacillus fermentum <400> 371 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gtccaattga ttgacggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgtttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcggt gcattagctt gttggtgggg taatggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgca aactcgcgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc tt 1572 <210> 372 <211> 1572 <212> DNA <213> Lactobacillus fermentum <400> 372 tatgagagtt tgatcctggc tcaggatgaa cgccggcggt gtgcctaata catgcaagtc 60 gaacgcgttg gcccaattga ttgatggtgc ttgcacctga ttgattttgg tcgccaacga 120 gtggcggacg ggtgagtaac acgtaggtaa cctgcccaga agcgggggac aacatttgga 180 aacagatgct aataccgcat aacaacgttg ttcgcatgaa caacgcttaa aagatggctt 240 ctcgctatca cttctggatg gacctgcgct gcattagctt gttggtgggg taatggccta 300 ccaaggcgat gatgcatagc cgagttgaga gactgatcgg ccacaatggg actgagacac 360 ggcccatact cctacgggag gcagcagtag ggaatcttcc acaatgggcg caagcctgat 420 ggagcaacac cgcgtgagtg aagaagggtt tcggctcgta aagctctgtt gttaaagaag 480 aacacgtatg agagtaactg ttcatacgtt gacggtattt aaccagaaag tcacggctaa 540 ctacgtgcca gcagccgcgg taatacgtag gtggcaagcg ttatccggat ttattgggcg 600 taaagagagt gcaggcggtt ttctaagtct gatgtgaaag ccttcggctt aaccggagaa 660 gtgcatcgga aactggataa cttgagtgca gaagagggta gtggaactcc atgtgtagcg 720 gtggaatgcg tagatatatg gaagaacacc agtggcgaag gcggctacct ggtctgcaac 780 tgacgctgag actcgaaagc atgggtagcg aacaggatta gataccctgg tagtccatgc 840 cgtaaacgat gagtgctagg tgttggaggg tttccgccct tcagtgccgg agctaacgca 900 ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg 960 cccgcacaag cggtggagca tgtggtttaa ttcgaagcta cgcgaagaac cttaccaggt 1020 cttgacatct tgcgccaacc ctagagatag ggcgtttcct tcgggaacgc aatgacaggt 1080 ggtgcatggt cgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc 1140 aacccttgtt actagttgcc agcattaagt tgggcactct agtgagactg ccggtgacaa 1200 accggaggaa ggtggggacg acgtcagatc atcatgcccc ttatgacctg ggctacacac 1260 gtgctacaat ggacggtaca acgagtcgcg aactcgtgag ggcaagcaaa tctcttaaaa 1320 ccgttctcag ttcggactgc aggctgcaac tcgcctgcac gaagtcggaa tcgctagtaa 1380 tcgcggatca gcatgccgcg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca 1440 ccatgagagt ttgtaacacc caaagtcggt ggggtaacct tttaggagcc agccgcctaa 1500 ggtgggacag atgattaggg tgaagtcgta acaaggtagc cgtaggagaa cctgcggctg 1560 gatcacctcc tt 1572 <210> 373 <211> 1137 <212> DNA <213> Bacteroides thetaiotaomicron <400> 373 ctgaaccagc caagtagcgt gaaggatgac tgccctatgg gttgtaaact tcttttatat 60 gggaataaag ttttccacgt gtggaatttt gtatgtacca tatgaataag gatcggctaa 120 ctccgtgcca gcagccgcgg taatacggag gatccgagcg ttatccggat ttattgggtt 180 taaagggagc gtaggtggac agttaagtca gttgtgaaag tttgcggctc aaccgtaaaa 240 ttgcagttga tactggctgt cttgagtaca gtagaggtgg gcggaattcg tggtgtagcg 300 gtgaaatgct tagatatcac gaagaactcc gattgcgaag gcagctcact ggactgcaac 360 tgacactgat gctcgaaagt gtgggtatca aacaggatta gataccctgg tagtccacac 420 agtaaacgat gaatactcgc tgtttgcgat atacagtaag cggccaagcg aaagcattaa 480 gtattccacc tggggagtac gccggcaacg gtgaaactca aaggaattga cgggggcccg 540 cacaagcgga ggaacatgtg gtttaattcg atgatacgcg aggaacctta cccgggctta 600 aattgcattt gaatatattg gaaacagtat agccgtaagg caaatgtgaa ggtgctgcat 660 ggttgtcgtc agctcgtgcc gtgaggtgtc ggcttaagtg ccataacgag cgcaaccctt 720 atctttagtt actaacaggt catgctgagg actctagaga gactgccgtc gtaagatgtg 780 aggaaggtgg ggatgacgtc aaatcagcac ggcccttacg tccggggcta cacacgtgtt 840 acaatggggg gtacagaagg cagctacctg gtgacaggat gctaatccca aaagcctctc 900 tcagttcgga tcgaagtctg caacccgact tcgtgaagct ggattcgcta gtaatcgcgc 960 atcagccatg gcgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcaagccatg 1020 aaagccgggg gtacctgaag tacgtaaccg caaggagcgt cctagggtaa aactggtaat 1080 tggggctaag tcgtaacaag gtagccgtac cggaaggtgc ggctggaaca cctcctt 1137 <210> 374 <211> 1137 <212> DNA <213> Bacteroides thetaiotaomicron <400> 374 ctgaaccagc caagtagcgt gaaggatgac tgccctatgg gttgtaaact tcttttatat 60 gggaataaag ttttccacgt gtggaatttt gtatgtacca tatgaataag gatcggctaa 120 ctccgtgcca gcagccgcgg taatacggag gatccgagcg ttatccggat ttattgggtt 180 taaagggagc gtaggtggac agttaagtca gttgtgaaag tttgcggctc aaccgtaaaa 240 ttgcagttga tactggctgt cttgagtaca gtagaggtgg gcggaattcg tggtgtagcg 300 gtgaaatgct tagatatcac gaagaactcc gattgcgaag gcagctcact ggactgcaac 360 tgacactgat gctcgaaagt gtgggtatca aacaggatta gataccctgg tagtccacac 420 agtaaacgat gaatactcgc tgtttgcgat atacagtaag cggccaagcg aaagcattaa 480 gtattccacc tggggagtac gccggcaacg gtgaaactca aaggaattga cgggggcccg 540 cacaagcgga ggaacatgtg gtttaattcg atgatacgcg aggaacctta cccgggctta 600 aattgcattt gaatatattg gaaacagtat agccgtaagg caaatgtgaa ggtgctgcat 660 ggttgtcgtc agctcgtgcc gtgaggtgtc ggcttaagtg ccataacgag cgcaaccctt 720 atctttagtt actaacaggt catgctgagg actctagaga gactgccgtc gtaagatgtg 780 aggaaggtgg ggatgacgtc aaatcagcac ggcccttacg tccggggcta cacacgtgtt 840 acaatggggg gtacagaagg cagctacctg gtgacaggat gctaatccca aaagcctctc 900 tcagttcgga tcgaagtctg caacccgact tcgtgaagct ggattcgcta gtaatcgcgc 960 atcagccatg gcgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcaagccatg 1020 aaagccgggg gtacctgaag tacgtaaccg caaggagcgt cctagggtaa aactggtaat 1080 tggggctaag tcgtaacaag gtagccgtac cggaaggtgc ggctggaaca cctcctt 1137 <210> 375 <211> 1525 <212> DNA <213> Bacteroides thetaiotaomicron <400> 375 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atttcagttt gcttgcaaac tggagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactcgggg atagcctttc gaaagaaaga ttaatacccg 180 atagtataat tagaccgcat ggtcttatta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag gcagttggtg aggtaacggc tcaccaaacc ttcgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg acgagagtct gaaccagcca agtagcgtga aggatgactg 420 ccctatgggt tgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggacag ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgata ctggctgtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactgg actgcaactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcatttga atatattgga aacagtatag 1020 ccgtaaggca aatgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtca tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctacctggt 1260 gacaggatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 376 <211> 1525 <212> DNA <213> Bacteroides thetaiotaomicron <400> 376 atgaagagtt tgatcctggc tcaggatgaa cgctagctac aggcttaaca catgcaagtc 60 gaggggcagc atttcagttt gcttgcaaac tggagatggc gaccggcgca cgggtgagta 120 acacgtatcc aacctgccga taactcgggg atagcctttc gaaagaaaga ttaatacccg 180 atggtataat tagaccgcat ggtcttgtta ttaaagaatt tcggttatcg atggggatgc 240 gttccattag gcagttggtg aggtaacggc tcaccaaacc ttcgatggat aggggttctg 300 agaggaaggt cccccacatt ggaactgaga cacggtccaa actcctacgg gaggcagcag 360 tgaggaatat tggtcaatgg gcgcaggcct gaaccagcca agtagcgtga aggatgactg 420 ccctatgggt tgtaaacttc ttttatatgg gaataaagtt ttccacgtgt ggaattttgt 480 atgtaccata tgaataagga tcggctaact ccgtgccagc agccgcggta atacggagga 540 tccgagcgtt atccggattt attgggttta aagggagcgt aggtggacag ttaagtcagt 600 tgtgaaagtt tgcggctcaa ccgtaaaatt gcagttgata ctggctgtct tgagtacagt 660 agaggtgggc ggaattcgtg gtgtagcggt gaaatgctta gatatcacga agaactccga 720 ttgcgaaggc agctcactgg actgcaactg acactgatgc tcgaaagtgt gggtatcaaa 780 caggattaga taccctggta gtccacacag taaacgatga atactcgctg tttgcgatat 840 acagtaagcg gccaagcgaa agcattaagt attccacctg gggagtacgc cggcaacggt 900 gaaactcaaa ggaattgacg ggggcccgca caagcggagg aacatgtggt ttaattcgat 960 gatacgcgag gaaccttacc cgggcttaaa ttgcatttga atatattgga aacagtatag 1020 ccgtaaggca aatgtgaagg tgctgcatgg ttgtcgtcag ctcgtgccgt gaggtgtcgg 1080 cttaagtgcc ataacgagcg caacccttat ctttagttac taacaggtca tgctgaggac 1140 tctagagaga ctgccgtcgt aagatgtgag gaaggtgggg atgacgtcaa atcagcacgg 1200 cccttacgtc cggggctaca cacgtgttac aatggggggt acagaaggca gctacctggt 1260 gacaggatgc taatcccaaa agcctctctc agttcggatc gaagtctgca acccgacttc 1320 gtgaagctgg attcgctagt aatcgcgcat cagccatggc gcggtgaata cgttcccggg 1380 ccttgtacac accgcccgtc aagccatgaa agccgggggt acctgaagta cgtaaccgca 1440 aggagcgtcc tagggtaaaa ctggtaattg gggctaagtc gtaacaaggt agccgtaccg 1500 gaaggtgcgg ctggaacacc tcctt 1525 <210> 377 <211> 1569 <212> DNA <213> Lactobacillus gasseri <400> 377 atgagagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg 60 agcgagcttg cctagatgaa tttggtgctt gcaccaaatg aaactagata caagcgagcg 120 gcggacgggt gagtaacacg tgggtaacct gcccaagaga ctgggataac acctggaaac 180 agatgctaat accggataac aacactagac gcatgtctag agtttaaaag atggttctgc 240 tatcactctt ggatggacct gcggtgcatt agctagttgg taaggtaacg gcttaccaag 300 gcaatgatgc atagccgagt tgagagactg atcggccaca ttgggactga gacacggccc 360 aaactcctac gggaggcagc agtagggaat cttccacaat ggacgcaagt ctgatggagc 420 aacgccgcgt gagtgaagaa gggtttcggc tcgtaaagct ctgttggtag tgaagaaaga 480 tagaggtagt aactggcctt tatttgacgg taattactta gaaagtcacg gctaactacg 540 tgccagcagc cgcggtaata cgtaggtggc aagcgttgtc cggatttatt gggcgtaaag 600 cgagtgcagg cggttcaata agtctgatgt gaaagccttc ggctcaaccg gagaattgca 660 tcagaaactg ttgaacttga gtgcagaaga ggagagtgga actccatgtg tagcggtgga 720 atgcgtagat atatggaaga acaccagtgg cgaaggcggc tctctggtct gcaactgacg 780 ctgaggctcg aaagcatggg tagcgaacag gattagatac cctggtagtc catgccgtaa 840 acgatgagtg ctaagtgttg ggaggtttcc gcctctcagt gctgcagcta acgcattaag 900 cactccgcct ggggagtacg accgcaaggt tgaaactcaa aggaattgac gggggcccgc 960 acaagcggtg gagcatgtgg tttaattcga agcaacgcga agaaccttac caggtcttga 1020 catccagtgc aaacctaaga gattaggagt tcccttcggg gacgctgaga caggtggtgc 1080 atggctgtcg tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg agcgcaaccc 1140 ttgtcattag ttgccatcat taagttgggc actctaatga gactgccggt gacaaaccgg 1200 aggaaggtgg ggatgacgtc aagtcatcat gccccttatg acctgggcta cacacgtgct 1260 acaatggacg gtacaacgag aagcgaacct gcgaaggcaa gcggatctct gaaagccgtt 1320 ctcagttcgg actgtaggct gcaactcgcc tacacgaagc tggaatcgct agtaatcgcg 1380 gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcacaccatg 1440 agagtctgta acacccaaag ccggtgggat aacctttata ggagtcagcc gtctaaggta 1500 ggacagatga ttagggtgaa gtcgtaacaa ggtagccgta ggagaacctg cggctggatc 1560 acctccttt 1569 <210> 378 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 378 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 379 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 379 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 380 <211> 1557 <212> DNA <213> Enterococcus faecium <400> 380 tatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgctttt tctttcaccg gagcttgctc caccgaaaga aaaagagtgg cgaacgggtg 120 agtaacacgt gggtaacctg cccatcagaa ggggataaca cttggaaaca ggtgctaata 180 ccgtataaca ctattttccg catggaagaa agttgaaagg cgcttttgcg tcactgatgg 240 atggacccgc ggtgcattag ctagttggtg aggtaacggc tcaccaaggc aacgatgcat 300 agccgacctg agagggtgat cggccacact gggactgaga cacggcccag actcctacgg 360 gaggcagcag tagggaatct tcggcaatgg acgaaagtct gaccgagcaa cgccgcgtga 420 gtgaagaagg ttttcggatc gtaaaactct gttgttagag aagaacaagg atgagagtag 480 aacgttcatc ccttgacggt atctaaccag aaagccacgg ctaactacgt gccagcagcc 540 gcggtaatac gtaggtggca agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc 600 ggtttcttaa gtctgatgtg aaagcccccg gctcaaccgg ggagggtcat tggaaactgg 660 gagacttgag tgcagaagag gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata 720 tatggaggaa caccagtggc gaaggcggct ctctggtctg taactgacgc tgaggctcga 780 aagcgtgggg agcgaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc 840 taagtgttgg agggtttccg cccttcagtg ctgcagcaaa cgcattaagc actccgcctg 900 gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg 960 agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atcctttgac 1020 cactctagag atagagcttc cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt 1080 cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaaccct tattgttagt 1140 tgccatcatt tagttgggca ctctagcgag actgccggtg acaaaccgga ggaaggtggg 1200 gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta caatgggaag 1260 tacaacgagt tgcgaagtcg cgaggctaag ctaatctctt aaagcttctc tcagttcgga 1320 ttgtaggctg caactcgcct acatgaagcc ggaatcgcta gtaatcgcgg atcagcacgc 1380 cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga gagtttgtaa 1440 cacccgaagt cggtgaggta acctttttgg agccagccgc ctaaggtggg atagatgatt 1500 ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctccttt 1557 <210> 381 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 381 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 382 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 382 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaacggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggttaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 383 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 383 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg cactgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 384 <211> 1566 <212> DNA <213> Lactobacillus_casei_paracasei <400> 384 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatggaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcttggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctcctt 1566 <210> 385 <211> 1567 <212> DNA <213> Lactobacillus_casei_paracasei <400> 385 tatgagagtt tgatcctggc tcaggatgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgagttc tcgttgatga tcggtgcttg caccgagatt caacatagaa cgagtggcgg 120 acgggtgagt aacacgtggg taacctgccc ttaagtgggg gataacattt ggaaacagat 180 gctaataccg catagatcca agaaccgcat ggttcctggc tgaaagatgg cgtaagctat 240 cgcttttgga tggacccgcg gcgtattagc tagttggtga ggtaatggct caccaaggcg 300 atgatacgta gccgaactga gaggttgatc ggccacattg ggactgagac acggcccaaa 360 ctcctacggg aggcagcagt agggaatctt ccacaatgga cgcaagtctg atggagcaac 420 gccgcgtgag tgaagaaggc tttcgggtcg taaaactctg ttgttggaga agaatggtcg 480 gcagagtaac tgttgtcggc gtgacggtat ccaaccagaa agccacggct aactacgtgc 540 cagcagccgc ggtaatacgt aggtggcaag cgttatccgg atttattggg cgtaaagcga 600 gcgcaggcgg ttttttaagt ctgatgtgaa agccctcggc ttaaccgagg aagcgcatcg 660 gaaactggga aacttgagtg cagaagagga cagtggaact ccatgtgtag cggtgaaatg 720 cgtagatata tggaagaaca ccagtggcga aggcggctgt ctggtctgta actgacgctg 780 aggctcgaaa gcatgggtag cgaacaggat tagataccct ggtagtccat gccgtaaacg 840 atgaatgcta ggtgttggag ggtttccgcc cttcagtgcc gcagctaacg cattaagcat 900 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca 960 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat 1020 cttttgatca cctgagagat caggtttccc cttcgggggc aaaatgacag gtggtgcatg 1080 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccctta 1140 tgactagttg ccagcattta gttgggcact ctagtaagac tgccggtgac aaaccggagg 1200 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca 1260 atggatggta caacgagttg cgagaccgcg aggtcaagct aatctcttaa agccattctc 1320 agttcggact gtaggctgca actcgcctac acgaagtcgg aatcgctagt aatcgcggat 1380 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccatgaga 1440 gtttgtaaca cccgaagccg gtggcgtaac ccttttaggg agcgagccgt ctaaggtggg 1500 acaaatgatt agggtgaagt cgtaacaagg tagccgtagg agaacctgcg gctggatcac 1560 ctccttt 1567 <210> 386 <211> 1563 <212> DNA <213> Lactobacillus plantarum <400> 386 tttgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagtc 60 gaacgaactc tggtattgat tggtgcttgc atcatgattt acatttgagt gagtggcgaa 120 ctggtgagta acacgtggga aacctgccca gaagcggggg ataacacctg gaaacagatg 180 ctaataccgc ataacaactt ggaccgcatg gtccgagttt gaaagatggc ttcggctatc 240 acttctggat ggtcccgcgg cgtattagct agatggtggg gtaacggctc accatggcaa 300 tgatacgtag ccgacctgag agggtaatcg gccacattgg gactgagaca cggcccaaac 360 tcctacggga ggcagcagta gggaatcttc cacaatggac gaaagtctga tggagcaacg 420 ccgcgtgagt gaagaagggt ttcggctcgt aaaactctgt tgttaaagaa gaacatatct 480 gagagtaact gttcaggtat tgacggtatt taaccagaaa gccacggcta actacgtgcc 540 agcagccgcg gtaatacgta ggtggcaagc gttgtccgga tttattgggc gtaaagcgag 600 cgcaggcggt tttttaagtc tgatgtgaaa gccttcggct caaccgaaga agtgcatcgg 660 aaactgggaa acttgagtgc agaagaggac agtggaactc catgtgtagc ggtgaaatgc 720 gtagatatat ggaagaacac cagtggcgaa ggcggctgtc tggtctgtaa ctgacgctga 780 ggctcgaaag tatgggtagc aaacaggatt agataccctg gtagtccata ccgtaaacga 840 tgaatgctaa gtgttggagg gtttccgccc ttcagtgctg cagctaacgc attaagcatt 900 ccgcctgggg agtacggccg caaggctgaa actcaaagga attgacgggg gcccgcacaa 960 gcggtggagc atgtggttta attcgaagct acgcgaagaa ccttaccagg tcttgacata 1020 ctatgcaaat ctaagagatt agacgttccc ttcggggaca tggatacagg tggtgcatgg 1080 ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccttat 1140 tatcagttgc cagcattaag ttgggcactc tggtgagact gccggtgaca aaccggagga 1200 aggtggggat gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa 1260 tggatggtac aacgagttgc gaactcgcga gagcaagcta atctcttaaa gccattctca 1320 gttcggattg taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc 1380 agcatgccgc ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accatgagag 1440 tttgtaacac ccaaagtcgg tggggtaacc ttttaggaac cagccgccta aggtgggaca 1500 gatgattagg gtgaagtcgt aacaaggtag ccgtaggaga acctgcggct ggatcacctc 1560 ctt 1563 <210> 387 <211> 1441 <212> DNA <213> Enterobacter cloacae <400> 387 agcggcggac gggtgagtaa tgtctgggaa actgcctgat ggagggggat aactactgga 60 aacggtagct aataccgcat aacgtcgcaa gaccaaagag ggggaccttc gggcctcttg 120 ccatcagatg tgcccagatg ggattagcta gtaggtgggg taacggctca cctaggcgac 180 gatccctagc tggtctgaga ggatgaccag ccacactgga actgagacac ggtccagact 240 cctacgggag gcagcagtgg ggaatattgc acaatgggcg caagcctgat gcagccatgc 300 cgcgtgtatg aagaaggcct tcgggttgta aagtactttc agcggggagg aaggcgttga 360 ggttaataac ctcagcgatt gacgttaccc gcagaagaag caccggctaa ctccgtgcca 420 gcagccgcgg taatacggag ggtgcaagcg ttaatcggaa ttactgggcg taaagcgcac 480 gcaggcggtc tgtcaagtcg gatgtgaaat ccccgggctc aacctgggaa ctgcattcga 540 aactggcagg ctagagtctt gtagaggggg gtagaattcc aggtgtagcg gtgaaatgcg 600 tagagatctg gaggaatacc ggtggcgaag gcggccccct ggacaaagac tgacgctcag 660 gtgcgaaagc gtggggagca aacaggatta gataccctgg tagtccacgc cgtaaacgat 720 gtcgacttgg aggttgtgcc cttgaggcgt ggcttccgga gctaacgcgt taagtcgacc 780 gcctggggag tacggccgca aggttaaaac tcaaatgaat tgacgggggc ccgcacaagc 840 ggtggagcat gtggtttaat tcgatgcaac gcgaagaacc ttacctactc ttgacatcca 900 gagaactttc cagagatgga ttggtgcctt cgggaactct gagacaggtg ctgcatggct 960 gtcgtcagct cgtgttgtga aatgttgggt taagtcccgc aacgagcgca acccttatcc 1020 tttgttgcca gcggttcggc cgggaactca aaggagactg ccagtgataa actggaggaa 1080 ggtggggatg acgtcaagtc atcatggccc ttacgagtag ggctacacac gtgctacaat 1140 ggcgcataca aagagaagcg acctcgcgag agcaagcgga cctcataaag tgcgtcgtag 1200 tccggattgg agtctgcaac tcgactccat gaagtcggaa tcgctagtaa tcgtagatca 1260 gaatgctacg gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca ccatgggagt 1320 gggttgcaaa agaagtaggt agcttaacct tcgggagggc gcttaccact ttgtgattca 1380 tgactggggt gaagtcgtaa caaggtaacc gtaggggaac ctgcggttgg atcacctcct 1440 t 1441 <210> 388 <211> 1538 <212> DNA <213> Escherichia coli <400> 388 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaatcagc ttgctgattc gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aaccttgtag agatacgagg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 389 <211> 1538 <212> DNA <213> Escherichia coli <400> 389 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 390 <211> 1538 <212> DNA <213> Escherichia coli <400> 390 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 391 <211> 1538 <212> DNA <213> Escherichia coli <400> 391 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 392 <211> 1538 <212> DNA <213> Escherichia coli <400> 392 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 393 <211> 1538 <212> DNA <213> Escherichia coli <400> 393 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aaccttgtag agatacgagg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 394 <211> 1538 <212> DNA <213> Escherichia coli <400> 394 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gaacggtaac aggaagaagc ttgcttcttt gctgacgagt ggcggacggg tgagtaatgt 120 ctgggaaact gcctgatgga gggggataac tactggaaac ggtagctaat accgcataac 180 gtcgcaagac caaagagggg gaccttcggg cctcttgcca tcggatgtgc ccagatggga 240 ttagctagta ggtggggtaa aggctcacct aggcgacgat ccctagctgg tctgagagga 300 tgaccagcca cactggaact gagacacggt ccagactcct acgggaggca gcagtgggga 360 atattgcaca atgggcgcaa gcctgatgca gccatgccgc gtgtatgaag aaggccttcg 420 ggttgtaaag tactttcagc ggggaggaag ggagtaaagt taataccttt gctcattgac 480 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt 540 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtttgt taagtcagat 600 gtgaaatccc cgggctcaac ctgggaactg catctgatac tggcaagctt gagtctcgta 660 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt 720 ggcgaaggcg gccccctgga cgaagactga cgctcaggtg cgaaagcgtg gggagcaaac 780 aggattagat accctggtag tccacgccgt aaacgatgtc gacttggagg ttgtgccctt 840 gaggcgtggc ttccggagct aacgcgttaa gtcgaccgcc tggggagtac ggccgcaagg 900 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg 960 atgcaacgcg aagaacctta cctggtcttg acatccacag aaccttgtag agatacgagg 1020 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat 1080 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg 1140 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc 1200 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc 1260 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg 1320 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc 1380 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc 1440 ttaaccttcg ggagggcgct taccactttg tgattcatga ctggggtgaa gtcgtaacaa 1500 ggtaaccgta ggggaacctg cggttggatc acctcctt 1538 <210> 395 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 395 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc ggtgaggtta ataacctcat cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggcttaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa ctttccagag atggattggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 396 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 396 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc gttaaggtta ataaccttgg cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa ctttccagag atggattggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 397 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 397 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataatgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc ggtgaggtta ataacctcat cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa ctttccagag atggattggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 398 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 398 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc gttaaggtta ataaccttgg cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa ctttccagag atggattggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt tcggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 399 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 399 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataatgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc ggtgaggtta ataaccttgg cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa cttagcagag atgctttggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 400 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 400 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc ggtgaggtta ataacctcat cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggcttaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa ctttccagag atggattggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 401 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 401 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataatgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agcttgtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc ggtgaggtta ataacctcat cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa cttagcagag atgctttggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 402 <211> 1536 <212> DNA <213> Klebsiella pneumoniae <400> 402 ttgaagagtt tgatcatggc tcagattgaa cgctggcggc aggcctaaca catgcaagtc 60 gagcggtagc acagagagct tgctctcggg tgacgagcgg cggacgggtg agtaatgtct 120 gggaaactgc ctgatggagg gggataacta ctggaaacgg tagctaatac cgcataacgt 180 cgcaagacca aagtggggga ccttcgggcc tcatgccatc agatgtgccc agatgggatt 240 agctagtagg tggggtaacg gctcacctag gcgacgatcc ctagctggtc tgagaggatg 300 accagccaca ctggaactga gacacggtcc agactcctac gggaggcagc agtggggaat 360 attgcacaat gggcgcaagc ctgatgcagc catgccgcgt gtgtgaagaa ggccttcggg 420 ttgtaaagca ctttcagcgg ggaggaaggc gttaaggtta ataacctcat cgattgacgt 480 tacccgcaga agaagcaccg gctaactccg tgccagcagc cgcggtaata cggagggtgc 540 aagcgttaat cggaattact gggcgtaaag cgcacgcagg cggtctgtca agtcggatgt 600 gaaatccccg ggctcaacct gggaactgca ttcgaaactg gcaggctaga gtcttgtaga 660 ggggggtaga attccaggtg tagcggtgaa atgcgtagag atctggagga ataccggtgg 720 cgaaggcggc cccctggaca aagactgacg ctcaggtgcg aaagcgtggg gagcaaacag 780 gattagatac cctggtagtc cacgccgtaa acgatgtcga tttggaggtt gtgcccttga 840 ggcgtggctt ccggagctaa cgcgttaaat cgaccgcctg gggagtacgg ccgcaaggtt 900 aaaactcaaa tgaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgat 960 gcaacgcgaa gaaccttacc tggtcttgac atccacagaa cttagcagag atgctttggt 1020 gccttcggga actgtgagac aggtgctgca tggctgtcgt cagctcgtgt tgtgaaatgt 1080 tgggttaagt cccgcaacga gcgcaaccct tatcctttgt tgccagcggt ccggccggga 1140 actcaaagga gactgccagt gataaactgg aggaaggtgg ggatgacgtc aagtcatcat 1200 ggcccttacg accagggcta cacacgtgct acaatggcat atacaaagag aagcgacctc 1260 gcgagagcaa gcggacctca taaagtatgt cgtagtccgg attggagtct gcaactcgac 1320 tccatgaagt cggaatcgct agtaatcgta gatcagaatg ctacggtgaa tacgttcccg 1380 ggccttgtac acaccgcccg tcacaccatg ggagtgggtt gcaaaagaag taggtagctt 1440 aaccttcggg agggcgctta ccactttgtg attcatgact ggggtgaagt cgtaacaagg 1500 taaccgtagg ggaacctgcg gttggatcac ctcctt 1536 <210> 403 <211> 1255 <212> DNA <213> Fusobacterium nucleatum <400> 403 gctcaccaag gcgatgatgg gtagccggcc tgagagggtg atcggccaca aggggactga 60 gacacggccc ttactcctac gggaggcagc agtggggaat attggacaat ggaccaagag 120 tctgatccag caattctgtg tgcacgatga agtttttcgg aatgtaaagt gctttcagtt 180 gggaagaaaa aaatgacggt accaacagaa gaagtgacgg ctaaatacgt gccagcagcc 240 gcggtaatac gtatgtcaca agcgttatcc ggatttattg ggcgtaaagc gcgtctaggt 300 ggttatgtaa gtctgatgtg aaaatgcagg gctcaactct gtattgcgtt ggaaactgtg 360 taactagagt actggagagg taagcggaac tacaagtgta gaggtgaaat tcgtagatat 420 ttgtaggaat gccgatgggg aagccagctt actggacaga tactgacgct gaagcgcgaa 480 agcgtgggta gcaaacagga ttagataccc tggtagtcca cgccgtaaac gatgattact 540 aggtgttggg ggtcgaacct cagcgcccaa gcaaacgcga taagtaatcc gcctggggag 600 tacgtacgca agtatgaaac tcaaaggaat tgacggggac ccgcacaagc ggtggagcat 660 gtggtttaat tcgacgcaac gcgaggaacc ttaccagcgt ttgacatctt aggaatgaga 720 cagagatgtt tcagtgtccc ttcggggaaa cctaaagaca ggtggtgcat ggctgtcgtc 780 agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct ttcgtatgtt 840 accatcatta agttggggac tcatgcgata ctgcctgcga tgagcaggag gaaggtgggg 900 atgacgtcaa gtcatcatgc cccttatacg ctgggctaca cacgtgctac aatgggtagt 960 acagagagtc gcaaagccgt gaggtggagc taatctcaga aaactattct tagttcggat 1020 tgtactctgc aactcgagta catgaagttg gaatcgctag taatcgcgaa tcagcaatgt 1080 cgcggtgaat acgttctcgg gtcttgtaca caccgcccgt cacaccacga gagttggttg 1140 cacctgaagt agcaggccta accgtaagga gggatgctcc gagggtgtga ttagcgattg 1200 gggtgaagtc gtaacaaggt atccgtacgg gaacgtgcgg atggatcacc tcctt 1255 <210> 404 <211> 1521 <212> DNA <213> Butyrivibrio_sp. <400> 404 ttgagagttt gatcctggct caggatgaac gctggcggcg tgcttaacac atgcaagtcg 60 aacggacgga ttggagcttg ctccatgaag ttagtggcgg acgggtgagt aacgcgtggg 120 taacctgccc tatgcagggg gataacgttt ggaaacgaac gctaataccg cataacctag 180 ttggttcgca tgaaccgact agcaaagatt ttatcggcat aggatggacc cgcgttggat 240 tagctagttg gtgagataac agcccaccaa ggcaacgatc catagccggc ctgagagggt 300 gaacggccac actgggactg agacacggcc cagactccta cgggaggcag cagtggggaa 360 tattgcacaa tgggcgcaag cctgatgcag cgacgccgcg tgaaggatga aggtcttcgg 420 atcgtaaact tctatcagca gggaagaaac catgacggta cctgactaag aagccccggc 480 taactacgtg ccagcagccg cggtaatacg tagggggcaa gcgttatccg gaattactgg 540 gtgtaaaggg tgcgtaggcg gcgatttaag tcagatgtga aaactcaggg ctcaaccttg 600 agactgcatc tgaaactgag ttgctagagt gcaggagagg aaagcggaat tccgagtgta 660 gcggtgaaat gcgtagagat tcggaggaac accagtagcg aaggcggctt tctggactgt 720 aactgacgct gaggcacgaa agcgtgggga gcgaacagga ttagataccc tggtagtcca 780 cgccgtaaac gatgaatact aggtgtcggg gcttacgggt ctcggtgccg cagctaacgc 840 attaagtatt ccacctggga agtacgaccg caaggttgaa actcaaagga attgacgggg 900 acccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa ccttacctaa 960 acttgacatc cctttgaccg gtccttaatc ggatctttac tagcttgcta gtacaaaggt 1020 gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa 1080 cgagcgcaac ccctatcttt agtagccatc attcagttgg gcactctaga gagactgcca 1140 gggataacct ggaggaaggt ggggatgacg tcaaatcatc atgcccctta tgtttagggc 1200 tacacacgtg ctacaatggg tgctacaaag ggaagcaaat ccgcgaggcc gagcaaatct 1260 caaaaaagca ctcccagttc ggattgtagt ctgcaactcg actacatgaa gttggaatcg 1320 ctagtaatcg cgaatcagaa tgtcgcggtg aatacgttcc cgggtcttgt acacaccgcc 1380 cgtcacacca tgggagttgg gggggcccaa cgccagtgac ctaacccgca agggaaggag 1440 ctgtctaagg caaaaccaat gactggggtg aagtcgtaac aaggtagccg tatcggaagg 1500 tgcggctgga tcacctcctt t 1521 <210> 405 <211> 1177 <212> DNA <213> Ruminococcus obeum <400> 405 cctacgggag gcagcagtgg ggaatattgc acaatggggg aaaccctgat gcagcgacgc 60 cgcgtgaagg aagaagtatc tcggtatgta aacttctatc agcagggaag atagtgacgg 120 tacctgacta agaagccccg gctaactacg tgccagcagc cgcggtaata cgtagggggc 180 aagcgttatc cggatttact gggtgtaaag ggagcgtaga cggactggca agtctgatgt 240 gaaaggcggg ggctcaaccc ctggactgca ttggaaactg ttagtcttga gtgccggaga 300 ggtaagcgga attcctagtg tagcggtgaa atgcgtagat attaggagga acaccagtgg 360 cgaaggcggc ttactggacg gtaactgacg ttgaggctcg aaagcgtggg gagcaaacag 420 gattagatac cctggtagtc cacgccgtaa acgatgaata ctaggtgttg gggagcaaag 480 ctcttcggtg ccgccgcaaa cgcattaagt attccacctg gggagtacgt tcgcaagaat 540 gaaactcaaa ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa 600 gcaacgcgaa gaaccttacc aagtcttgac atccctctga ccgactctta accgagtctt 660 tccttcggga cagaggagac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt 720 tgggttaagt cccgcaacga gcgcaacccc tatccccagt agccagcggt tcggccgggc 780 actctgagga gactgccagg gataacctgg aggaaggcgg ggatgacgtc aaatcatcat 840 gccccttatg atttgggcta cacacgtgct acaatggcgt aaacaaaggg aagcaagcct 900 gcgaaggtaa gcaaatccca aaaataacgt cccagttcgg actgcagtct gcaactcgac 960 tgcacgaagc tggaatcgct agtaatcgcg gatcagaatg ccgcggtgaa tacgttcccg 1020 ggtcttgtac acaccgcccg tcacaccatg ggagtcagta acgcccgaag tcagtgacct 1080 aaccgcaagg gaggagctgc cgaaggcggg accgatgact ggggtgaagt cgtaacaagg 1140 tagccgtatc ggaaggtgcg gctggatcac ctccttt 1177

Claims (49)

1. 치료적 유효량의 마이크로바이옴(microbiome) 조성물을 포함하는 조성물로서, 대상체의 마이크로바이옴에서 적어도 하나의 항생제 저항 유전자의 존재비(abundance)를 감소시키는 데 사용하기 위한 포자 형성자 세균(spore-former bacteria)을 포함하는, 조성물.
2. 치료적 유효량의 마이크로바이옴 조성물을 포함하는 조성물로서, 약물 내성 세균의 바람직하지 않은 수준 또는 집단을 가질 위험이 있거나 또는 가지는 것으로 진단된 대상체를 치료하기 위해 사용하기 위한 하나 이상의 건강한 인간 개체로부터 유래된 후벽균(Firmicutes)을 포함하는, 조성물.
3. 대상체의 마이크로바이옴에서 항생제 내성 세균의 존재비를 감소시키는 용도를 위한 ROAR 조성물.
4. 체액 또는 노폐물과의 선택적 접촉을 포함하여, 직접 또는 간접적으로 접촉할 가능성이 큰 적어도 2 개체에 투여함으로써, 항생제 내성 유전자의 전달 주기를 방해하는 용도를 위한 ROAR 조성물.
5. 제 1 항 또는 제 4 항에 있어서, 상기 항생제 내성 유전자(들)가 표 1에 열거된 것들로부터 선택되는, 조성물.
6. 제 5 항에 있어서, 상기 표 1의 적어도 2, 3, 4, 5, 6, 7, 8, 9, 10개, 또는 그 초과의 항생제 내성 유전자의 존재비가 감소된, 조성물.
7. 제 1 항 내지 제 6 항 중 어느 한 항에 있어서, 상기 약물 또는 항생제가 표 2에 열거된 약물 종류로부터 유래된, 조성물.
8. 제 1 항 내지 제 7 항 중 어느 한 항에 있어서, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25개 또는 그 초과의 항생제 내성 유전자 또는 약물 종류의 존재비를 감소시키는 것을 추가로 포함하는, 조성물.
9. 제 1 항 내지 제 8 항 중 어느 한 항에 있어서, 상기 조성물은 표 3에 열거된 하나 이상의 종을 포함하는, 조성물.
10. 제 9 항에 있어서, 상기 조성물은 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함하는, 조성물.
11. 제 9 항 또는 제 10 항에 있어서, 상기 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는, 조성물.
12. 제 1 항 내지 제 11 항 중 어느 한 항에 있어서, 상기 조성물은 표 4의 하나 이상의 종을 포함하지 않는, 조성물.
13. 제 1 항 내지 제 12 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 포자의 형태인, 조성물.
14. 제 1 항 내지 제 13 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 배양되는, 조성물.
15. 제 1 항 내지 제 14 항 중 어느 한 항에 있어서, 상기 조성물은 후벽군 및 하나 이상의 박테로이데스(Bacteroides) 종을 포함하는, 조성물.
16. 제 1 항 내지 제 15 항 중 어느 한 항에 있어서, 상기 대상체가 퀴놀론 내성, 베타-락탐 내성 및 카바페넴 내성 세균으로 이루어진 군으로부터 선택된 1, 2 또는 3 개의 세균의 감소된 존재비를 갖는, 조성물.
17. 제 1 항 내지 제 16 항 중 어느 한 항에 있어서, 상기 대상체가 항생제 치료에 비반응성이었던, 조성물.
18. 제 1 항 내지 제 17 항 중 어느 한 항에 있어서, 상기 대상체가 C. 디피실리(C.difficile) 감염되거나 또는 발병할 위험이 있는, 조성물.
19. 제 1 항 내지 제 18 항 중 어느 한 항에 있어서, 상기 대상체가 대장염을 앓거나 또는 발병할 위험이 있는, 조성물.
20. 제 19 항에 있어서, 상기 대장염이 크론병 또는 궤양성 대장염인, 조성물.
21. 제 20 항에 있어서, 상기 대장염이 경증 내지 중등도의 궤양성 대장염인, 조성물.
22. 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비 감소와 관련된 세균 종을 포함하는 조성물.
23. 제 22 항에 있어서, 상기 항생제 내성 유전자(들)가 표 1에 열거된 것들로부터 선택되는, 조성물.
24. 제 23 항에 있어서, 상기 표 1의 적어도 2, 3, 4, 5, 6, 7, 8, 9, 10개 또는 그 초과의 항생제 내성 유전자의 존재비가 감소된, 조성물.
25. 제 22 항 내지 제 24 항 중 어느 한 항에 있어서, 상기 항생제는 표 2에 열거된 종류로부터 유래된, 조성물.
26. 제 22 항 내지 제 25 항 중 어느 한 항에 있어서, 상기 조성물은 표 3에 열거된 하나 이상의 종을 포함하는, 조성물.
27. 제 26 항에 있어서, 상기 조성물은 표 3에 열거된 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개 또는 그 초과의 종을 포함하는, 조성물.
28. 제 20 항 내지 제 27 항 중 어느 한 항에 있어서, 상기 종은 표 5에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는, 조성물.
29. 제 22 항 내지 제 28 항 중 어느 한 항에 있어서, 상기 조성물은 표 4의 하나 이상의 종을 포함하지 않고, 선택적으로 표 4의 하나 이상의 종이 표 6에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는, 조성물.
30. 제 22 항 내지 제 29 항 중 어느 한 항에 있어서, 상기 조성물은 하나 이상의 후벽군 종을 포함하는, 조성물.
31. 제 22 항 내지 제 30 항 중 어느 한 항에 있어서, 상기 조성물은 하나 이상의 박테로이데스 종을 포함하는, 조성물.
32. 제 22 항 내지 제 31 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 포자의 형태인, 조성물.
33. 제 22 항 내지 제 32 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 건강한 대상체의 배설물(feces)로부터 유래된 포자 분획으로부터 수득되는, 조성물.
34. 제 22 항 내지 제 33 항 중 어느 한 항에 있어서, 상기 조성물은 하나 이상의 후벽군 종, 및 선택적으로 하나 이상의 박테로이데스 종을 조성물 중 유일한 세균 종으로서 포함하는, 조성물.
35. 제 22 항 내지 제 34 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 배양되는, 조성물.
36. 세균을 포함하는 조성물로서, 상기 조성물이 투여되는 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는 용도를 위한 조성물.
37. 제 36 항에 있어서, 상기 조성물 중 세균이 건강한 대상체의 배설물로부터 유래된 포자 분획으로부터 수득되는, 조성물.
38. 제 36 항에 있어서, 상기 세균이 대상체에서 하나 이상의 항생제 내성 유전자의 존재비 감소와 관련되도록 선택되는, 조성물.
39. 제 36 항 내지 제 38 항 중 어느 한 항에 있어서, 상기 항생제 내성 유전자(들)가 표 1로부터 선택되는, 조성물.
40. 제 36 항 내지 제 39 항 중 어느 한 항에 있어서, 상기 조성물은 표 3에서 선택된 적어도 하나의 종을 포함하는, 조성물.
41. 제 36 항 내지 제 40 항 중 어느 한 항에 있어서, 상기 조성물은 표 4의 종을 포함하지 않는, 조성물.
42. 조성물이 투여되는 대상체에서 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키는 데 유용한 세균 조성물을 확인하는 방법으로서, 표 3의 하나 이상의 세균 종의 존재에 대해 상기 조성물을 스크리닝하는 단계를 포함하고, 상기 세균 조성물에서 표 3의 하나 이상의 종의 검출은 적어도 하나의 항생제 내성 유전자의 존재비를 감소시키기 위해 사용될 수 있는 조성물의 확인을 나타내는, 방법.
43. 제 42 항에 있어서, 상기 스크리닝이 상기 조성물 중 표 5의 하나 이상의 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열의 검출을 포함하는 방법.
44. 제 42 항 또는 제 43 항에 있어서, 표 4의 하나 이상의 세균 종의 존재에 대한 스크리닝을 추가로 포함하고, 선택적으로 표 4의 하나 이상의 종은 표 6에 열거된 16S rDNA, V4 및/또는 V6 서열, 또는 이에 대해 적어도 95% 동일성을 갖는 서열을 포함하는, 방법.
45. 치료 방법에 사용하기 위해 잠재적 공여자의 배설물을 스크리닝하는 방법으로서, 표 3 또는 표 4의 세균 종의 존재에 대해 잠재적 공여자로부터의 배설물 샘플을 시험하는 단계를 포함하고, 표 3으로부터 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 될 수 있음을 나타내지만, 표 4로부터 하나 이상의 종의 검출은 잠재적 공여자가 공여자가 되지 않아야 함을 나타내는, 방법.
46. 대상체가 ROAR 조성물을 사용하는 치료로부터 이익을 얻을 수 있는지를 결정하는 방법으로서, 상기 대상체로부터의 샘플이 표 4의 하나 이상의 세균 종을 포함하는지를 결정하는 단계를 포함하고, 표 4로부터 하나 이상의 종의 검출은 상기 대상체가 ROAR 조성물을 사용하는 치료로부터 이익을 얻을 수 있다는 점을 나타내는, 방법.
47. 제 22 항 내지 제 41 항 중 어느 한 항에 있어서, 상기 조성물 중의 세균이 항생제 내성의 동물 모델에서 하나 이상의 항생제 내성 유전자(들)의 존재비를 감소시키는 능력을 나타내는, 조성물.
48. 제 47 항에 있어서, 상기 동물 모델은 하나 이상의 항생제로 처리된 후 하나 이상의 항생제 내성 유전자를 보유하는 하나 이상의 세균으로 콜로니화된 마우스를 포함하는, 조성물.
49. 제 48 항에 있어서, 상기 마우스가 반코마이신 내성 세균 또는 반코마이신 및 카바페넴 내성 세균으로 콜로니화되는, 조성물.

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