KR900000077A - 일정 수분을 함유하는 서방형 제제 - Google Patents

일정 수분을 함유하는 서방형 제제 Download PDF

Info

Publication number
KR900000077A
KR900000077A KR1019890007506A KR890007506A KR900000077A KR 900000077 A KR900000077 A KR 900000077A KR 1019890007506 A KR1019890007506 A KR 1019890007506A KR 890007506 A KR890007506 A KR 890007506A KR 900000077 A KR900000077 A KR 900000077A
Authority
KR
South Korea
Prior art keywords
weight
formulation
alcohol
formulation according
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019890007506A
Other languages
English (en)
Other versions
KR0136279B1 (ko
Inventor
하필드 쟌느
토마스 레스러 스튜워트
떼레즈 안뜨와네트 말코와스카 산드라
존 닐 필립
Original Assignee
에프.샤레
유로셀티크 소시에떼 아노님
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에프.샤레, 유로셀티크 소시에떼 아노님 filed Critical 에프.샤레
Publication of KR900000077A publication Critical patent/KR900000077A/ko
Application granted granted Critical
Publication of KR0136279B1 publication Critical patent/KR0136279B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

내용 없음

Description

일정수분을 함유하는 서방형 제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (11)

  1. 3알킬크산틴, 적어도 하나의 친수성 또는 소수성 중합체, 융점이 25~90℃인 적어도 하나의 왁스와 2-10중량%, 바람직하게는 4-9중량%의 물을 포함함을 특징으로 하는 서방형 경구용 고형제제.
  2. 제1항에 있어서, 수분의 함량은 제제의 중량에 대하여 4-8%, 바람직하게는 5-7%임을 특징으로 하는 제제.
  3. 제1항 또는 제2항의 어느한항에 있어서, 3-알킬크산틴은 1,3-디메틸크산틴, 바람직하게는 테오필린임을 특징으로 하는 제제.
  4. 제3항에 있어서, 테오필린은 제제중에 40-85중량%, 바람직하게는 50-80중량%포함함을 특징으로 하는 제제.
  5. 제1항 내지 제4항의 어느한항에 있어서, 적어도 하나의 친수성 또는 소수성 중합체를 1-20중량%, 바람직하게는 2-12중량%포함함을 특징으로 하는 제제.
  6. 제1항 내지 제5항의 어느한항에 있어서, 적어도 하나의 친수성 또는 소수성 중합체는 셀룰로오즈에테르, 바람직하게는 하이드록시 알킬셀룰로오즈에테르 또는 카르복시알킬셀룰로오즈임을 특징으로 하는 제제.
  7. 제6항에 있어서, 셀룰로오즈에테르는 하이드록시 프로필 셀룰로오즈, 하이드록시 메틸셀룰로오즈 또는 하이드록시 에틸 셀룰로오즈, 바람직하게는 하이드록시 에틸 셀룰로오즈임을 특징으로 하는 제제.
  8. 제1항 내지 제7항의 어느한항에 있어서, 제제중 적어도 하나의 왁스는 4-40중량%, 바람직하게는 8-36중량%포함함을 특징으로 하는 제제.
  9. 제1항 내지 제8항의 어느한항에 있어서, 적어도 하나의 왁수는 폴릴알킬글리콜, 지방산, 지방산 에스테르 또는 지방족 알코올로 바람직하게는 C12-C36지방족 알코올임을 특징으로 하는 제제.
  10. 제9항에 있어서, 지방족 알코올은 C14-C22지방족 알코올, 바람직하게는 미리스틸알코올, 스테아릴알코올, 세틸알코올 또는 세토스테아릴 알코올, 특히 바람직하게는 세틸알코올이나 세토스테아릴 알코올임을 특징으로 하는 방법.
  11. 제1항 내지 제10항중 어느한항에 있어서, 제형에 정제임을 특징으로 하는 제제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890007506A 1988-06-02 1989-06-01 일정수분을 함유하는 서방형 제제 Expired - Lifetime KR0136279B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888813064A GB8813064D0 (en) 1988-06-02 1988-06-02 Controlled release dosage forms having defined water content
GB8813064 1988-06-02

Publications (2)

Publication Number Publication Date
KR900000077A true KR900000077A (ko) 1990-01-30
KR0136279B1 KR0136279B1 (ko) 1998-04-25

Family

ID=10637952

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890007506A Expired - Lifetime KR0136279B1 (ko) 1988-06-02 1989-06-01 일정수분을 함유하는 서방형 제제

Country Status (19)

Country Link
US (1) US5091189A (ko)
EP (1) EP0344960B1 (ko)
JP (1) JPH0816060B2 (ko)
KR (1) KR0136279B1 (ko)
AT (1) ATE83925T1 (ko)
AU (1) AU610401B2 (ko)
CA (1) CA1323834C (ko)
DE (1) DE68904119T2 (ko)
DK (1) DK175130B1 (ko)
ES (1) ES2053989T3 (ko)
FI (1) FI93695C (ko)
GB (2) GB8813064D0 (ko)
GR (1) GR3007088T3 (ko)
IE (1) IE61998B1 (ko)
IL (1) IL90462A (ko)
NO (1) NO176232C (ko)
NZ (1) NZ229372A (ko)
PT (1) PT90722B (ko)
ZA (1) ZA894201B (ko)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
CA2314896C (en) * 1997-12-22 2005-09-13 Euro-Celtique, S.A. A method of preventing abuse of opioid dosage forms
JP2001526228A (ja) 1997-12-22 2001-12-18 ユーロ−セルティーク，エス．エイ． オピオイド作動薬／拮抗薬の併用
AU1738800A (en) 1998-11-23 2000-06-13 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
HU229705B1 (en) 2000-02-08 2014-05-28 Euro Celtique Sa Tamper-resistant oral opioid agonist formulations
CN1525851A (zh) 2001-05-11 2004-09-01 ������ҩ�����޹�˾ 抗滥用阿片样物质控释剂型
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
SI1416842T1 (sl) * 2001-07-18 2009-06-30 Euro Celtique Sa Farmacevtske kombinacije oksikodona in naloksona
ATE431738T1 (de) 2001-08-06 2009-06-15 Euro Celtique Sa Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist
AU2002324624A1 (en) 2001-08-06 2003-02-24 Euro-Celtique S.A. Sequestered antagonist formulations
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
IN192180B (ko) * 2001-09-28 2004-03-06 Ranbaxy Lab
CA2479350A1 (en) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
EP1492505B1 (en) 2002-04-05 2015-06-03 Euro-Celtique S.A. Pharmaceutical preparation containing oxycodone and naloxone
US7815934B2 (en) 2002-09-20 2010-10-19 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20040121010A1 (en) * 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
WO2004067039A1 (en) * 2003-01-28 2004-08-12 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
MY135852A (en) * 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
EP1604666A1 (en) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
ES2317313T3 (es) * 2004-10-19 2009-04-16 Krka, Tovarna Zdravil, D.D., Novo Mesto Composicion farmaceutica solida que comprende clorhidrato de donepezilo.
EP1702558A1 (en) * 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
EP1942875B1 (en) * 2005-08-24 2015-08-12 Rubicon Research Private Limited Controlled release formulation
SI2719378T1 (sl) 2006-06-19 2016-11-30 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
PL2068816T3 (pl) * 2006-09-29 2018-03-30 The Procter And Gamble Company Kompozycje do higieny jamy ustnej zawierające sieci żelowe
EP2224808A4 (en) * 2007-12-17 2013-11-27 Alpharma Pharmaceuticals Llc PHARMACEUTICAL COMPOSITION
US20100151014A1 (en) * 2008-12-16 2010-06-17 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
US8623418B2 (en) * 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
RU2478388C2 (ru) * 2008-07-07 2013-04-10 Еуро-Селтик С.А. Фармацевтическая композиция, содержащая опиоидный антагонист, для лечения задержки мочи
MY152279A (en) 2009-03-10 2014-09-15 Euro Celtique Sa Immediate release pharmaceutical compositions comprising oxycodone and naloxone
US10071089B2 (en) 2013-07-23 2018-09-11 Euro-Celtique S.A. Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
CN114053235B (zh) * 2020-08-07 2023-07-18 广州白云山光华制药股份有限公司 茶碱缓释片及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965256A (en) * 1972-05-16 1976-06-22 Synergistics Slow release pharmaceutical compositions
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
FR2535202B1 (fr) * 1982-11-03 1985-08-09 Fabre Sa Pierre Comprimes de theophylline a liberation controlee et leur procede de fabrication
US4743247A (en) * 1984-08-13 1988-05-10 Alza Corporation Process for manufacturing dosage form
US4753800A (en) * 1985-10-04 1988-06-28 Warner-Lambert Company Medicament adsorbates and their preparation
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
DE3750145T2 (de) * 1986-06-10 1994-11-03 Euro Celtique Sa Zusammensetzung mit kontrollierter Freisetzung von Dihydrocodein.
GB8626098D0 (en) * 1986-10-31 1986-12-03 Euro Celtique Sa Controlled release hydromorphone composition
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids

Also Published As

Publication number Publication date
IE891744L (en) 1989-12-02
ZA894201B (en) 1990-03-28
GR3007088T3 (ko) 1993-07-30
DE68904119T2 (de) 1993-06-09
IL90462A0 (en) 1990-01-18
FI93695C (fi) 1995-05-26
DE68904119D1 (de) 1993-02-11
DK175130B1 (da) 2004-06-14
GB8813064D0 (en) 1988-07-06
JPH0225420A (ja) 1990-01-26
JPH0816060B2 (ja) 1996-02-21
AU610401B2 (en) 1991-05-16
NO176232B (no) 1994-11-21
NO176232C (no) 1995-03-01
ES2053989T3 (es) 1994-08-01
EP0344960A2 (en) 1989-12-06
DK266889D0 (da) 1989-06-01
IE61998B1 (en) 1994-12-14
FI93695B (fi) 1995-02-15
FI892664L (fi) 1989-12-03
GB2219207B (en) 1992-01-02
ATE83925T1 (de) 1993-01-15
GB8911629D0 (en) 1989-07-05
EP0344960B1 (en) 1992-12-30
NO892229D0 (no) 1989-06-01
IL90462A (en) 1993-01-31
PT90722B (pt) 1994-11-30
US5091189A (en) 1992-02-25
FI892664A0 (fi) 1989-06-01
NZ229372A (en) 1991-07-26
KR0136279B1 (ko) 1998-04-25
AU3512789A (en) 1989-12-07
NO892229L (no) 1989-12-04
EP0344960A3 (en) 1990-03-07
DK266889A (da) 1989-12-03
PT90722A (pt) 1989-12-29
CA1323834C (en) 1993-11-02
GB2219207A (en) 1989-12-06

Similar Documents

Publication Publication Date Title
KR900000077A (ko) 일정 수분을 함유하는 서방형 제제
YU47258B (sh) Postupak za dobijanje čvrstog preparata sa produženim oslobadjanjem aktivnog jedinjenja
ATE299017T1 (de) Arzneimittel
KR880000089A (ko) 서방형 약제 조성물
DE69927963D1 (de) Gelierbare pharmazeutische zusammensetzungen
SE8504580L (sv) Bladliknande preparat
DK456985D0 (da) Forbedret vehikel for afgivelse af aktive farmaceutiske ingredienser til human hud
ES2038643T3 (es) Procedimiento para la obtencion de una composicion farmaceutica topica.
KR950010875A (ko) 피부외용제
ES462418A1 (es) Un procedimiento para la preparacion de composiciones biolo-gicamente activas.
KR900701310A (ko) 인터페론 경비투여용 제제
DE69210879D1 (de) Gellanester
ES8400028A1 (es) Metodo de preparacion de una composicion tixotropica anhidra.
JPS57126414A (en) Ointment
FR2449686B1 (fr) Nouvel ester de l'acide 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetique et sa preparation, ainsi que medicament le comprenant et sa preparation
JPS53139716A (en) Pharmaceutical preparation of stable prostaglandine
ES2102013T3 (es) Procedimiento para la obtencion de alquil- y/o alquenil-oligoglucosidos.
NO912890L (no) Preparat inneholdende salicylsyre for behandling av hudsykdommer med avskalling.
KR890006209A (ko) 분말형 메이크업화장의 분사식 고정제 조성물
JPS5679626A (en) Semi-solid medicine
KR920007620A (ko) 실리마린 및 약학 또는 화장품조성물의 용해방법
KR930700158A (ko) 피부 자극 완화 조성물 및 이것을 함유하는 경피외용제
SE8401748L (sv) Antimykotiskt medel i form av krem med hoggradig frigoring av verksam substans
GB1028226A (en) Improvements in or relating to vitamin a derivatives
JPS57206609A (en) Solution for external use

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19890601

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19940523

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19890601

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19970818

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19971030

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 19980121

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 19980121

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20001229

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20011222

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20021218

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20031219

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20041221

Start annual number: 8

End annual number: 8

PR1001 Payment of annual fee

Payment date: 20051226

Start annual number: 9

End annual number: 9

PR1001 Payment of annual fee

Payment date: 20061219

Start annual number: 10

End annual number: 10

PR1001 Payment of annual fee

Payment date: 20080103

Start annual number: 11

End annual number: 11

PR1001 Payment of annual fee

Payment date: 20090105

Start annual number: 12

End annual number: 12

PR1001 Payment of annual fee

Payment date: 20100112

Start annual number: 13

End annual number: 13

PR1001 Payment of annual fee

Payment date: 20110118

Start annual number: 14

End annual number: 14

FPAY Annual fee payment

Payment date: 20120117

Year of fee payment: 15

PR1001 Payment of annual fee

Payment date: 20120117

Start annual number: 15

End annual number: 15

EXPY Expiration of term
PC1801 Expiration of term

Termination date: 20131009

Termination category: Expiration of duration