LT2247558T - Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimui - Google Patents
Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimuiInfo
- Publication number
- LT2247558T LT2247558T LTEPPCT/US2009/000961T LT09000961T LT2247558T LT 2247558 T LT2247558 T LT 2247558T LT 09000961 T LT09000961 T LT 09000961T LT 2247558 T LT2247558 T LT 2247558T
- Authority
- LT
- Lithuania
- Prior art keywords
- imaging agents
- neurological dysfunction
- novel imaging
- detecting neurological
- detecting
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title 1
- 230000009251 neurologic dysfunction Effects 0.000 title 1
- 208000015015 neurological dysfunction Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6610108P | 2008-02-14 | 2008-02-14 | |
| PCT/US2009/000961 WO2009102498A1 (en) | 2008-02-14 | 2009-02-17 | Novel imaging agents for detecting neurological dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2247558T true LT2247558T (lt) | 2022-04-11 |
Family
ID=40627498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/US2009/000961T LT2247558T (lt) | 2008-02-14 | 2009-02-17 | Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimui |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8318132B2 (lt) |
| EP (2) | EP2247558B2 (lt) |
| JP (1) | JP2011512354A (lt) |
| KR (1) | KR20100135235A (lt) |
| CA (1) | CA2715390A1 (lt) |
| CY (1) | CY1125258T1 (lt) |
| DK (1) | DK2247558T4 (lt) |
| ES (1) | ES2907992T5 (lt) |
| FI (1) | FI2247558T4 (lt) |
| HR (1) | HRP20220401T4 (lt) |
| HU (1) | HUE058352T2 (lt) |
| LT (1) | LT2247558T (lt) |
| PL (1) | PL2247558T5 (lt) |
| PT (1) | PT2247558T (lt) |
| SI (1) | SI2247558T2 (lt) |
| WO (1) | WO2009102498A1 (lt) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2247558T (lt) | 2008-02-14 | 2022-04-11 | Eli Lilly And Company | Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimui |
| US8932557B2 (en) * | 2008-02-14 | 2015-01-13 | Eli Lilly And Company | Imaging agents for detecting neurological dysfunction |
| US20110201656A1 (en) * | 2008-08-08 | 2011-08-18 | Neurosearch A/S | Novel diphenyl 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors |
| EP2323696B1 (en) * | 2008-09-18 | 2018-09-05 | Cedars-Sinai Medical Center | Optical method for the detection of alzheimer's disease |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
| CA2815960C (en) * | 2010-10-29 | 2019-01-22 | Clino Ltd. | Tau imaging probe |
| US20140275156A1 (en) * | 2011-08-11 | 2014-09-18 | Neuprotect Pty Ltd | Flavonoid compounds, and methods of use thereof |
| US20130315825A1 (en) * | 2012-05-03 | 2013-11-28 | Washington University | Tricyclic heteroaromatic compounds as alpha-synuclein ligands |
| KR101609504B1 (ko) * | 2012-05-22 | 2016-04-05 | 일라이 릴리 앤드 캄파니 | 신경계 기능장애를 검출하기 위한 카르볼린계 및 카르바졸계 영상화제 |
| KR20190136125A (ko) | 2012-12-21 | 2019-12-09 | 국립연구개발법인 양자과학기술연구개발기구 | 뇌 안에 축적된 타우 단백질을 이미징하기 위한 신규한 화합물 |
| WO2014194169A1 (en) * | 2013-05-31 | 2014-12-04 | The General Hospital Corporation | Radiosynthesis of tau radiopharmaceuticals |
| MX2015016771A (es) | 2013-06-25 | 2016-03-31 | Squibb Bristol Myers Co | Compuestos de carbazol carboxamida utiles como inhibidores de cinasa. |
| TWI648272B (zh) | 2013-06-25 | 2019-01-21 | 美商必治妥美雅史谷比公司 | 經取代之四氫咔唑及咔唑甲醯胺化合物 |
| NO3055308T3 (lt) * | 2013-10-08 | 2018-04-21 | ||
| TWI667233B (zh) | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
| US10662193B2 (en) | 2014-01-21 | 2020-05-26 | Ac Immune Sa | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins |
| SI3143011T1 (sl) | 2014-05-13 | 2021-08-31 | F. Hoffmann-La Roche Ag | Devterirane heterociklične spojine in njihova uporaba kot kontrastna sredstva |
| JP6487534B2 (ja) | 2014-09-05 | 2019-03-20 | シンビオミックス セラピューティクス、エルエルシー | 細菌性膣炎の治療に使用するためのセクニダゾール |
| AU2015311730A1 (en) * | 2014-09-05 | 2017-04-20 | Allosteros Therapeutics, Inc | Camkii inhibitors and uses thereof |
| AR102426A1 (es) | 2014-10-24 | 2017-03-01 | Bristol Myers Squibb Co | Compuestos de indolcarboxamida como inhibidores de btk |
| EA031614B1 (ru) | 2014-10-24 | 2019-01-31 | Бристол-Майерс Сквибб Компани | Трициклические атропоизомерные соединения |
| PE20171239A1 (es) | 2014-10-24 | 2017-08-24 | Bristol Myers Squibb Co | Derivados de carbazol |
| CA2973648C (en) | 2015-02-02 | 2023-09-26 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
| CN105524034B (zh) * | 2015-03-27 | 2018-08-17 | 北京大学 | 香豆素衍生物的制备、药理作用及治疗脑缺血的应用 |
| CN105566269B (zh) * | 2015-03-27 | 2018-07-10 | 北京大学 | 香豆素衍生物的制备、药理作用及治疗瘙痒的应用 |
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| EP3118202A1 (en) | 2015-07-15 | 2017-01-18 | AC Immune S.A. | Dihydropyridopyrrole derivatives as tau-pet-ligands |
| EP3322707A1 (en) | 2015-07-15 | 2018-05-23 | AC Immune SA | Novel imaging compounds |
| US10301308B2 (en) | 2015-11-13 | 2019-05-28 | Eli Lilly And Company | Azetidine derivatives for tau imaging |
| EP3411083A1 (en) * | 2016-02-03 | 2018-12-12 | Janssen Pharmaceutica NV | Tau pet imaging ligands |
| JP7059270B2 (ja) | 2016-07-22 | 2022-04-25 | エーシー・イミューン・エス・アー | タウタンパク質凝集体を画像化するための化合物 |
| IL264239B (en) * | 2016-07-22 | 2022-08-01 | Ac Immune Sa | Compounds for imaging tau protein aggregates |
| WO2018024643A1 (en) | 2016-08-02 | 2018-02-08 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
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| CN109689653B (zh) | 2016-09-09 | 2022-04-12 | 豪夫迈·罗氏有限公司 | 用于制备2-(6-硝基吡啶-3-基)-9H-二吡啶并[2,3-b;3’,4’-d]吡咯的方法 |
| TW201906818A (zh) * | 2017-05-31 | 2019-02-16 | 美商511製藥公司 | 新穎氘取代之正子發射斷層掃描(pet)顯影劑及其藥理應用 |
| EP3743423A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Gamma-carboline compounds for the detection of tau aggregates |
| EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
| JPWO2019168170A1 (ja) * | 2018-03-02 | 2021-03-04 | 国立大学法人 長崎大学 | クロモン誘導体及びアミロイド関連疾患診断用組成物 |
| JP7293343B2 (ja) | 2018-05-09 | 2023-06-19 | アプリノイア セラピューティクス リミテッド | ヘテロアリール化合物及びその使用 |
| WO2021055670A1 (en) | 2019-09-20 | 2021-03-25 | Avx Corporation | Somatic cell-based electrical biosensor |
| CA3161455A1 (en) | 2019-11-13 | 2021-05-20 | Aprinoia Therapeutics Limited | Compounds for degrading tau protein aggregates and uses thereof |
| US12280037B2 (en) | 2020-09-22 | 2025-04-22 | Evofem Biosciences, Inc. | Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof |
| US20240368106A1 (en) * | 2021-08-30 | 2024-11-07 | Pretzel Therapeutics, Inc. | Hydroxy and alkoxy coumarins as modulators of polrmt |
| WO2023034346A1 (en) * | 2021-08-30 | 2023-03-09 | Pretzel Therapeutics, Inc. | Chromen-2-one modulators of polrmt |
| US11938127B2 (en) | 2021-09-28 | 2024-03-26 | Wayne State University | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders |
| DK4426434T3 (da) | 2021-11-02 | 2025-11-10 | Flare Therapeutics Inc | Pparg inverse agonists and uses thereof |
| WO2023204967A1 (en) * | 2022-04-21 | 2023-10-26 | Virginia Commonwealth University | Nlrp3 inflammasome inhibitors and compositions and uses thereof |
| JP2025513455A (ja) | 2022-04-22 | 2025-04-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | 疼痛の治療のためのヘテロアリール化合物 |
| EP4658651A1 (en) | 2023-02-02 | 2025-12-10 | Eli Lilly and Company | Novel compounds for tau imaging |
| WO2025155625A1 (en) | 2024-01-16 | 2025-07-24 | Eli Lilly And Company | Novel compounds for tau imaging |
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| EP1815872A4 (en) * | 2004-11-26 | 2011-06-15 | Univ Nagasaki | COMPOSITION FOR THE DIAGNOSIS OF AMYLOID ASSOCIATED DISEASE |
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| LT2247558T (lt) | 2008-02-14 | 2022-04-11 | Eli Lilly And Company | Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimui |
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| NO3055308T3 (lt) | 2013-10-08 | 2018-04-21 | ||
| CA2973648C (en) | 2015-02-02 | 2023-09-26 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
-
2009
- 2009-02-17 LT LTEPPCT/US2009/000961T patent/LT2247558T/lt unknown
- 2009-02-17 US US12/372,717 patent/US8318132B2/en active Active
- 2009-02-17 US US12/867,502 patent/US20110046378A1/en not_active Abandoned
- 2009-02-17 SI SI200932157T patent/SI2247558T2/sl unknown
- 2009-02-17 HR HRP20220401TT patent/HRP20220401T4/hr unknown
- 2009-02-17 FI FIEP09711194.2T patent/FI2247558T4/fi active
- 2009-02-17 WO PCT/US2009/000961 patent/WO2009102498A1/en not_active Ceased
- 2009-02-17 DK DK09711194.2T patent/DK2247558T4/da active
- 2009-02-17 HU HUE09711194A patent/HUE058352T2/hu unknown
- 2009-02-17 EP EP09711194.2A patent/EP2247558B2/en active Active
- 2009-02-17 PT PT97111942T patent/PT2247558T/pt unknown
- 2009-02-17 PL PL09711194.2T patent/PL2247558T5/pl unknown
- 2009-02-17 EP EP20130157487 patent/EP2599763A1/en not_active Withdrawn
- 2009-02-17 KR KR1020107020589A patent/KR20100135235A/ko not_active Ceased
- 2009-02-17 ES ES09711194T patent/ES2907992T5/es active Active
- 2009-02-17 JP JP2010546795A patent/JP2011512354A/ja active Pending
- 2009-02-17 CA CA2715390A patent/CA2715390A1/en not_active Abandoned
-
2022
- 2022-03-30 CY CY20221100245T patent/CY1125258T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009102498A1 (en) | 2009-08-20 |
| PT2247558T (pt) | 2022-03-21 |
| FI2247558T4 (fi) | 2024-09-19 |
| ES2907992T5 (en) | 2025-03-19 |
| KR20100135235A (ko) | 2010-12-24 |
| US20110046378A1 (en) | 2011-02-24 |
| US20110091382A1 (en) | 2011-04-21 |
| PL2247558T5 (pl) | 2024-10-14 |
| EP2247558B1 (en) | 2022-02-02 |
| HUE058352T2 (hu) | 2022-07-28 |
| SI2247558T2 (sl) | 2024-10-30 |
| CY1125258T1 (el) | 2024-02-16 |
| DK2247558T3 (da) | 2022-02-21 |
| CA2715390A1 (en) | 2009-08-20 |
| SI2247558T1 (sl) | 2022-07-29 |
| ES2907992T3 (es) | 2022-04-27 |
| EP2599763A1 (en) | 2013-06-05 |
| EP2247558A1 (en) | 2010-11-10 |
| HRP20220401T3 (hr) | 2022-05-27 |
| JP2011512354A (ja) | 2011-04-21 |
| EP2247558B2 (en) | 2024-07-03 |
| DK2247558T4 (da) | 2024-07-29 |
| US8318132B2 (en) | 2012-11-27 |
| PL2247558T3 (pl) | 2022-05-02 |
| HRP20220401T4 (hr) | 2024-09-27 |
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