LT2400973T - Pten ekstraląstelinės formos, kuri gali būti naudojama navikų gydymui, identifikavimas - Google Patents

Pten ekstraląstelinės formos, kuri gali būti naudojama navikų gydymui, identifikavimas

Info

Publication number
LT2400973T
LT2400973T LTEP10744058.8T LT10744058T LT2400973T LT 2400973 T LT2400973 T LT 2400973T LT 10744058 T LT10744058 T LT 10744058T LT 2400973 T LT2400973 T LT 2400973T
Authority
LT
Lithuania
Prior art keywords
pten
identification
treat tumors
extracellular form
extracellular
Prior art date
Application number
LTEP10744058.8T
Other languages
English (en)
Inventor
Ramon Parsons
Original Assignee
The Trustees Of Columbia University In The City Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Trustees Of Columbia University In The City Of New York filed Critical The Trustees Of Columbia University In The City Of New York
Publication of LT2400973T publication Critical patent/LT2400973T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP10744058.8T 2009-02-17 2010-02-17 Pten ekstraląstelinės formos, kuri gali būti naudojama navikų gydymui, identifikavimas LT2400973T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20797409P 2009-02-17 2009-02-17
PCT/US2010/000469 WO2010096173A2 (en) 2009-02-17 2010-02-17 Identification of extracellular form of pten that can be used to treat tumors

Publications (1)

Publication Number Publication Date
LT2400973T true LT2400973T (lt) 2017-04-10

Family

ID=42634379

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP10744058.8T LT2400973T (lt) 2009-02-17 2010-02-17 Pten ekstraląstelinės formos, kuri gali būti naudojama navikų gydymui, identifikavimas

Country Status (19)

Country Link
US (1) US9017981B2 (lt)
EP (1) EP2400973B1 (lt)
JP (2) JP5767117B2 (lt)
CN (1) CN102387810B (lt)
AU (2) AU2010216370A1 (lt)
BR (1) BRPI1005951A2 (lt)
CA (1) CA2752590C (lt)
CY (1) CY1118861T1 (lt)
DK (1) DK2400973T3 (lt)
ES (1) ES2623393T3 (lt)
HR (1) HRP20170306T1 (lt)
HU (1) HUE032028T2 (lt)
LT (1) LT2400973T (lt)
MX (1) MX2011008695A (lt)
PL (1) PL2400973T3 (lt)
PT (1) PT2400973T (lt)
SI (1) SI2400973T1 (lt)
SM (1) SMT201700159T1 (lt)
WO (1) WO2010096173A2 (lt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011218037B2 (en) * 2010-02-17 2016-10-13 The Trustees Of Columbia University In The City Of New York Use of PTEN-long leader sequence for transmembrane delivery of molecules
WO2015105957A1 (en) 2014-01-08 2015-07-16 Shriners Hospitals For Children Pten antagonist peptides and methods of using the same
US20200085890A1 (en) * 2016-07-29 2020-03-19 Ohio State Innovation Foundation Expression of pten-long with ocolytic viruses
CN109022461B (zh) * 2017-06-08 2022-01-14 中山大学附属第一医院 一种PTEN基因的上游开放阅读框45aa-uORF核苷酸序列及其编码的多肽的应用
CN108504671A (zh) * 2018-03-28 2018-09-07 宁波市医疗中心李惠利医院 一种PTEN-Long蛋白纯化制备方法
CN112236131A (zh) 2018-03-29 2021-01-15 技术研究及发展基金有限公司 包含pten抑制剂的囊泡及其用途
CA3134665A1 (en) * 2019-04-12 2020-10-15 Therapten Biosciences Inc. Compositions and methods to manufacture tumor suppressor fusions
CA3149478A1 (en) * 2019-08-05 2021-02-11 Mesoblast International Sarl Cellular compositions comprising viral vectors and methods of treatment
CN112813046A (zh) * 2021-01-08 2021-05-18 北京大学 一种pten亚型蛋白及其应用
CN112877309B (zh) * 2021-02-19 2022-05-17 北京大学 一种N端延长型PTEN亚型PTENζ蛋白及其编码基因和应用
WO2024163335A2 (en) * 2023-01-30 2024-08-08 The Board Of Regents Of The University Of Texas System Pten gene therapy vectors and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482795B1 (en) * 1997-01-30 2002-11-19 Myriad Genetics, Inc. Tumor suppressor designated TS10q23.3
CA2410514A1 (en) * 2000-05-30 2001-12-06 Advanced Research & Technology Institute Compositions and methods for identifying agents which modulate pten function and pi-3 kinase pathways
WO2004093820A2 (en) * 2003-04-23 2004-11-04 University Of Massachusetts Methods and compositions for solid tumor treatment
CA2581423A1 (en) 2004-09-23 2006-03-30 Vasgene Therapeutics, Inc. Polipeptide compounds for inhibiting angiogenesis and tumor growth
AU2011218037B2 (en) 2010-02-17 2016-10-13 The Trustees Of Columbia University In The City Of New York Use of PTEN-long leader sequence for transmembrane delivery of molecules

Also Published As

Publication number Publication date
JP2015231372A (ja) 2015-12-24
HUE032028T2 (en) 2017-08-28
EP2400973A2 (en) 2012-01-04
PT2400973T (pt) 2017-03-07
AU2010216370A1 (en) 2011-09-22
EP2400973B1 (en) 2016-11-30
CA2752590C (en) 2017-08-22
BRPI1005951A2 (pt) 2016-10-11
HRP20170306T1 (hr) 2017-04-21
WO2010096173A2 (en) 2010-08-26
JP5973035B2 (ja) 2016-08-17
JP2012517827A (ja) 2012-08-09
SMT201700159T1 (it) 2017-05-08
CA2752590A1 (en) 2010-08-26
EP2400973A4 (en) 2013-02-27
US9017981B2 (en) 2015-04-28
JP5767117B2 (ja) 2015-08-19
DK2400973T3 (en) 2017-03-06
AU2016231517A1 (en) 2016-10-06
CN102387810B (zh) 2017-08-04
CY1118861T1 (el) 2018-01-10
US20120039861A1 (en) 2012-02-16
MX2011008695A (es) 2011-10-14
AU2016231517B2 (en) 2018-01-25
SI2400973T1 (sl) 2017-05-31
CN102387810A (zh) 2012-03-21
ES2623393T3 (es) 2017-07-11
WO2010096173A3 (en) 2010-10-21
PL2400973T3 (pl) 2017-09-29

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