LT2630954T - Levodopos įvedimas į plaučius - Google Patents

Levodopos įvedimas į plaučius

Info

Publication number
LT2630954T
LT2630954T LTEP13161929.8T LT13161929T LT2630954T LT 2630954 T LT2630954 T LT 2630954T LT 13161929 T LT13161929 T LT 13161929T LT 2630954 T LT2630954 T LT 2630954T
Authority
LT
Lithuania
Prior art keywords
levodopa
pulmonary delivery
pulmonary
delivery
Prior art date
Application number
LTEP13161929.8T
Other languages
English (en)
Inventor
Blair Jackson
David J. Bennett
Raymond T. Bartas
Dwaine F. Emerich
Original Assignee
Civitas Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Civitas Therapeutics, Inc. filed Critical Civitas Therapeutics, Inc.
Publication of LT2630954T publication Critical patent/LT2630954T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTEP13161929.8T 2002-03-20 2003-03-19 Levodopos įvedimas į plaučius LT2630954T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36647102P 2002-03-20 2002-03-20

Publications (1)

Publication Number Publication Date
LT2630954T true LT2630954T (lt) 2017-01-25

Family

ID=28454804

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13161929.8T LT2630954T (lt) 2002-03-20 2003-03-19 Levodopos įvedimas į plaučius

Country Status (13)

Country Link
US (7) US7879358B2 (lt)
EP (3) EP2630954B1 (lt)
JP (1) JP4384503B2 (lt)
AU (1) AU2003218307B8 (lt)
CA (1) CA2478980C (lt)
CY (1) CY1118517T1 (lt)
DK (2) DK2630954T3 (lt)
ES (3) ES2389156T3 (lt)
HU (1) HUE031167T2 (lt)
LT (1) LT2630954T (lt)
PT (3) PT1531798E (lt)
SI (1) SI2630954T1 (lt)
WO (1) WO2003079992A2 (lt)

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ES2625260T5 (es) 2009-03-26 2020-07-29 Pulmatrix Operating Co Inc Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
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BR112013007304B1 (pt) 2010-09-29 2021-12-14 Pulmatrix, Inc. Pós secos de cátion de metal monovalente para inalação
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KR20210075224A (ko) 2012-10-22 2021-06-22 키비타스 테라퓨틱스, 인코포레이티드. 파킨슨병의 빠른 경감을 위한 레보도파 제형
SG11201503128TA (en) * 2012-10-22 2015-05-28 Civitas Therapeutics Inc Reducing inter-patient variability of levodopa plasma concentrations
BR112015010601B1 (pt) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
US8545878B1 (en) * 2012-11-09 2013-10-01 Civitas Therapeutics, Inc. Capsules containing high doses of levodopa for pulmonary use
US20140150787A1 (en) 2012-12-04 2014-06-05 Civitas Therapeutics, Inc. Devices and methods for puncturing a capsule to release a powdered medicament therefrom
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US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
TWI589308B (zh) * 2014-03-25 2017-07-01 林信湧 一種用於治療帕金森氏症之吸入式醫藥組成物及其備製方法
EP3134077A4 (en) * 2014-04-21 2017-12-20 Civitas Therapeutics, Inc. Rapid relief of motor fluctuations in parkinson's disease
MA40910A (fr) 2014-11-07 2017-09-12 Civitas Therapeutics Inc Poudres de rapamycine pour administration pulmonaire
CN113197851A (zh) 2015-05-06 2021-08-03 辛纳吉勒公司 包含药物粒子的药用悬浮液、用于其配给的装置、以及其使用方法
WO2017004501A1 (en) 2015-07-02 2017-01-05 Civitas Therapeutics, Inc. Triptan powders for pulmonary delivery
WO2018138581A1 (en) 2017-01-30 2018-08-02 Globalmed, Inc. Heated respiratory hose assembly
US11517548B2 (en) * 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
JP2019108379A (ja) * 2019-03-05 2019-07-04 サイヴィタス セラピューティックス,インコーポレイテッド パーキンソン病の運動症状変動の迅速な緩和
IT202000030437A1 (it) * 2020-12-10 2022-06-10 Zambon Spa Metodo per la realizzazione di una polvere inalabile comprendente voriconazolo
US12005185B2 (en) * 2021-12-17 2024-06-11 Belhaven BioPharma Inc. Medical counter measures including dry powder formulations and associated methods
CN121443315A (zh) 2023-07-05 2026-01-30 上海汉都医药科技有限公司 药物组合物、含其的制剂、套装及其制备方法和应用

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Also Published As

Publication number Publication date
US20160058727A1 (en) 2016-03-03
CA2478980A1 (en) 2003-10-02
EP1531798A4 (en) 2010-11-03
EP1531798A2 (en) 2005-05-25
AU2003218307B2 (en) 2006-07-27
US20140105983A1 (en) 2014-04-17
CY1118517T1 (el) 2017-07-12
ES2487816T3 (es) 2014-08-25
US9155699B2 (en) 2015-10-13
EP1531798B1 (en) 2012-06-06
HUE031167T2 (hu) 2017-07-28
JP4384503B2 (ja) 2009-12-16
US20040018989A1 (en) 2004-01-29
AU2003218307B8 (en) 2006-08-31
US20130164349A1 (en) 2013-06-27
ES2389156T3 (es) 2012-10-23
EP2494962A2 (en) 2012-09-05
DK1531798T3 (da) 2012-08-13
US20110151008A1 (en) 2011-06-23
WO2003079992A2 (en) 2003-10-02
PT2494962E (pt) 2014-08-27
CA2478980C (en) 2008-07-15
US20180055800A1 (en) 2018-03-01
USRE43711E1 (en) 2012-10-02
JP2006507218A (ja) 2006-03-02
PT2630954T (pt) 2017-01-05
US7879358B2 (en) 2011-02-01
PT1531798E (pt) 2012-09-10
DK2630954T3 (en) 2017-01-23
US8404276B2 (en) 2013-03-26
EP2630954B1 (en) 2016-10-05
ES2609482T3 (es) 2017-04-20
AU2003218307A1 (en) 2003-10-08
EP2494962B1 (en) 2014-05-14
SI2630954T1 (sl) 2017-02-28
EP2630954A1 (en) 2013-08-28
US8586093B2 (en) 2013-11-19
EP2494962A3 (en) 2013-01-16
WO2003079992A3 (en) 2005-03-31

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