LT2970256T - Nauji oktahidro-pirolo[3,4-c]-pirolo dariniai ir jų analogai, kaip autotaksino inhibitoriai - Google Patents

Nauji oktahidro-pirolo[3,4-c]-pirolo dariniai ir jų analogai, kaip autotaksino inhibitoriai

Info

Publication number
LT2970256T
LT2970256T LTEP14708891.8T LT14708891T LT2970256T LT 2970256 T LT2970256 T LT 2970256T LT 14708891 T LT14708891 T LT 14708891T LT 2970256 T LT2970256 T LT 2970256T
Authority
LT
Lithuania
Prior art keywords
otahydro
autotaxyx
pyrolo
analogue
inhibitors
Prior art date
Application number
LTEP14708891.8T
Other languages
English (en)
Inventor
Jérome HERT
Daniel Hunziker
Patrizio Mattei
Harald Mauser
Guozhi Tang
Lisha Wang
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of LT2970256T publication Critical patent/LT2970256T/lt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEP14708891.8T 2013-03-12 2014-03-11 Nauji oktahidro-pirolo[3,4-c]-pirolo dariniai ir jų analogai, kaip autotaksino inhibitoriai LT2970256T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13158724 2013-03-12
PCT/EP2014/054631 WO2014139978A1 (en) 2013-03-12 2014-03-11 New octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors

Publications (1)

Publication Number Publication Date
LT2970256T true LT2970256T (lt) 2020-01-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP14708891.8T LT2970256T (lt) 2013-03-12 2014-03-11 Nauji oktahidro-pirolo[3,4-c]-pirolo dariniai ir jų analogai, kaip autotaksino inhibitoriai

Country Status (32)

Country Link
US (2) US20150376194A1 (lt)
EP (1) EP2970256B1 (lt)
JP (2) JP6483034B2 (lt)
KR (1) KR20150126036A (lt)
CN (1) CN105073748B (lt)
AR (1) AR095079A1 (lt)
AU (1) AU2014230943B8 (lt)
BR (1) BR112015022804A2 (lt)
CA (1) CA2901047A1 (lt)
CL (1) CL2015002386A1 (lt)
CR (1) CR20150436A (lt)
DK (1) DK2970256T3 (lt)
EA (1) EA035015B1 (lt)
ES (1) ES2763417T3 (lt)
HR (1) HRP20192274T1 (lt)
HU (1) HUE046776T2 (lt)
IL (1) IL240796B (lt)
LT (1) LT2970256T (lt)
MA (1) MA38432B1 (lt)
MX (1) MX373247B (lt)
MY (1) MY177574A (lt)
PE (1) PE20151605A1 (lt)
PH (1) PH12015501934A1 (lt)
PL (1) PL2970256T3 (lt)
PT (1) PT2970256T (lt)
RS (1) RS59682B1 (lt)
SG (1) SG11201507396YA (lt)
SI (1) SI2970256T1 (lt)
TW (1) TWI678368B (lt)
UA (1) UA115354C2 (lt)
WO (1) WO2014139978A1 (lt)
ZA (1) ZA201505944B (lt)

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