LT3412687T - Didžiųjų b ląstelių difuzinės limfomos gydymo būdai - Google Patents

Didžiųjų b ląstelių difuzinės limfomos gydymo būdai

Info

Publication number
LT3412687T
LT3412687T LTEP18164175.4T LT18164175T LT3412687T LT 3412687 T LT3412687 T LT 3412687T LT 18164175 T LT18164175 T LT 18164175T LT 3412687 T LT3412687 T LT 3412687T
Authority
LT
Lithuania
Prior art keywords
lymphoma
treatments
cell diffusion
diffusion
cell
Prior art date
Application number
LTEP18164175.4T
Other languages
English (en)
Inventor
Gerhard Zugmaier
Dirk Nagorsen
Juergen Scheele
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45023802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3412687(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Publication of LT3412687T publication Critical patent/LT3412687T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
LTEP18164175.4T 2010-10-27 2011-10-27 Didžiųjų b ląstelių difuzinės limfomos gydymo būdai LT3412687T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40710710P 2010-10-27 2010-10-27

Publications (1)

Publication Number Publication Date
LT3412687T true LT3412687T (lt) 2020-07-27

Family

ID=45023802

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP15195076.3T LT3018145T (lt) 2010-10-27 2011-10-27 Priemonės ir būdai dlbcl gydymui
LTEP18164175.4T LT3412687T (lt) 2010-10-27 2011-10-27 Didžiųjų b ląstelių difuzinės limfomos gydymo būdai

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP15195076.3T LT3018145T (lt) 2010-10-27 2011-10-27 Priemonės ir būdai dlbcl gydymui

Country Status (31)

Country Link
US (2) US9192665B2 (lt)
EP (3) EP3018145B1 (lt)
JP (3) JP5997168B2 (lt)
KR (1) KR101889995B1 (lt)
CN (2) CN105251003B (lt)
AU (1) AU2011322581B2 (lt)
CA (1) CA2815119C (lt)
CL (1) CL2013001138A1 (lt)
CR (1) CR20130245A (lt)
CY (3) CY1117155T1 (lt)
DK (3) DK3412687T3 (lt)
EA (1) EA032139B1 (lt)
ES (3) ES2787044T3 (lt)
HR (2) HRP20151444T4 (lt)
HU (3) HUE048639T2 (lt)
IL (3) IL225924A (lt)
LT (2) LT3018145T (lt)
MA (1) MA34619B1 (lt)
ME (1) ME02311B (lt)
MY (1) MY163057A (lt)
NZ (2) NZ609201A (lt)
PH (1) PH12013500826A1 (lt)
PL (3) PL3018145T3 (lt)
PT (3) PT2632954E (lt)
RS (3) RS54525B2 (lt)
SG (1) SG189869A1 (lt)
SI (3) SI3412687T1 (lt)
SM (3) SMT202000232T1 (lt)
TR (1) TR201808019T4 (lt)
UA (1) UA111175C2 (lt)
WO (1) WO2012055961A1 (lt)

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ES2417065T3 (es) 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
KR101889995B1 (ko) * 2010-10-27 2018-08-20 암젠 리서치 (뮌헨) 게엠베하 Dlbcl의 치료 수단 및 방법
SMT201700250T1 (it) 2010-11-10 2017-07-18 Amgen Res Munich Gmbh Prevenzione di effetti avversi provocati da domini leganti cd3 specifici
JO3529B1 (ar) 2013-02-08 2020-07-05 Amgen Res Munich Gmbh مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
CN105829349B (zh) * 2013-10-15 2023-02-03 斯克利普斯研究所 肽嵌合抗原受体t细胞开关和其用途
WO2016154621A1 (en) 2015-03-26 2016-09-29 The California Institute For Biomedical Research SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
EP3283113A4 (en) 2015-04-15 2018-12-05 The California Institute for Biomedical Research Optimized pne-based chimeric receptor t cell switches and uses thereof
BR112017024757A2 (pt) 2015-05-18 2018-11-13 TCR2 Therapeutics Inc. composições e métodos para reprogramação de tcr utilizando proteínas de fusão
MX2018004515A (es) * 2015-10-13 2019-04-15 Eureka Therapeutics Inc Agentes de anticuerpo especificos para cd19 humano y usos de los mismos.
EP3484516A4 (en) * 2016-07-14 2020-03-18 Fred Hutchinson Cancer Research Center MULTIPLE SPECIFIC BINDING DOMAIN CONSTRUCTS WITH DIFFERENT EPITOP BINDING FOR TREATING CANCER
WO2018026953A1 (en) 2016-08-02 2018-02-08 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
MX2019003899A (es) 2016-10-07 2019-08-14 Tcr2 Therapeutics Inc Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
KR102613430B1 (ko) 2016-10-19 2023-12-18 더 스크립스 리서치 인스티튜트 인간화된 표적화 모이어티 및/또는 최적화된 키메라 항원 수용체-상호작용 도메인을 갖는 키메라 항원 수용체 효과기 세포 스위치 및 이의 용도
AU2017363311A1 (en) 2016-11-22 2019-06-13 TCR2 Therapeutics Inc. Compositions and methods for TCR reprogramming using fusion proteins
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
EP3731850A4 (en) 2017-12-29 2021-12-01 Oncorus, Inc. ONCOLYTIC VIRUS DELIVERY OF THERAPEUTIC POLYPEPTIDES
US20220023430A1 (en) * 2018-11-13 2022-01-27 Lipoxen Technologies Limited Glycopolysialylation of blinatumomab
AU2020267378B2 (en) * 2019-05-03 2025-01-30 Kite Pharma, Inc. Methods of administering chimeric antigen receptor immunotherapy
BR112021022682A2 (pt) 2019-05-14 2022-02-22 Provention Bio Inc Métodos e composições para prevenir diabetes do tipo 1
UY38701A (es) 2019-05-21 2020-12-31 Novartis Ag Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
CN118994397A (zh) 2019-05-21 2024-11-22 诺华股份有限公司 针对bcma的三特异性结合分子及其用途
US12006366B2 (en) 2020-06-11 2024-06-11 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
US20220184208A1 (en) * 2020-12-04 2022-06-16 Morphosys Ag Anti-cd19 combination therapy
RS66868B1 (sr) 2021-01-28 2025-06-30 Regeneron Pharma Kompozicije i postupci za lečenje sindroma oslobađanja citokina
WO2022251253A1 (en) 2021-05-24 2022-12-01 Provention Bio, Inc. Methods for treating type 1 diabetes
CA3247475A1 (en) 2022-04-11 2023-10-19 Regeneron Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR THE DESTRUCTION OF UNIVERSAL TUMOR CELLS
JP2026506095A (ja) 2023-02-17 2026-02-20 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Cd3/taa二重特異性抗体に応答する誘導nk細胞

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AU612370B2 (en) 1987-05-21 1991-07-11 Micromet Ag Targeted multifunctional proteins
KR100508289B1 (ko) 1998-04-21 2005-08-17 마이크로메트 에이지 Cd19×cd3 특이 폴리펩티드 및 그의 용도
AU2004242846A1 (en) 2003-05-31 2004-12-09 Micromet Ag Pharmaceutical compositions comprising bispecific anti-CD3, anti-CD19 antibody constructs for the treatment of B-cell related disorders
DK1691833T3 (da) 2003-11-28 2010-05-03 Micromet Ag Præparater der omfatter polypeptider
HUE025945T2 (en) 2005-02-15 2016-07-28 Univ Duke Anti-CD19 antibodies and their applications in oncology
ES2417065T3 (es) * 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
CN101331151A (zh) * 2005-12-16 2008-12-24 麦克罗梅特股份公司 治疗肿瘤性疾病的方式和方法
SI1976886T1 (sl) * 2005-12-16 2015-03-31 Amgen Research (Munich) Gmbh Sredstva in postopki za zdravljenje tumorskih bolezni
JP5401314B2 (ja) 2006-09-08 2014-01-29 メディミューン,エルエルシー ヒト化抗cd19抗体ならびに癌、移植および自己免疫疾患の治療におけるその使用
CN109456410B (zh) 2007-04-03 2022-01-28 安进研发(慕尼黑)股份有限公司 跨物种特异性CD3-ε结合结构域
HRP20151168T1 (hr) * 2008-11-07 2015-12-04 Amgen Research (Munich) Gmbh Lijeäśenje akutne limfoblastiäśne leukemije
BR112012009778A2 (pt) 2009-10-27 2017-06-13 Micromet Ag regime de dosagem para administrar um anticorpo biespecífico de cd19xcd3
KR101889995B1 (ko) * 2010-10-27 2018-08-20 암젠 리서치 (뮌헨) 게엠베하 Dlbcl의 치료 수단 및 방법

Also Published As

Publication number Publication date
JP2018039838A (ja) 2018-03-15
CR20130245A (es) 2013-09-20
AU2011322581B2 (en) 2015-04-23
RS60094B1 (sr) 2020-05-29
SG189869A1 (en) 2013-06-28
HUE048639T2 (hu) 2020-08-28
US20130287778A1 (en) 2013-10-31
CL2013001138A1 (es) 2014-11-14
DK3412687T3 (da) 2020-05-11
HRP20151444T1 (hr) 2016-01-29
EP3018145B1 (en) 2018-04-04
EP3412687A1 (en) 2018-12-12
PT3412687T (pt) 2020-04-03
EP2632954A1 (en) 2013-09-04
EA201390387A1 (ru) 2013-10-30
PL3412687T3 (pl) 2020-07-27
HUE027678T2 (en) 2016-11-28
ES2563439T5 (es) 2022-02-04
DK3018145T3 (en) 2018-05-28
CY1123251T1 (el) 2021-10-29
UA111175C2 (uk) 2016-04-11
SMT202000232T1 (it) 2020-07-08
EP2632954B2 (en) 2021-07-07
JP6522722B2 (ja) 2019-05-29
PH12013500826A1 (en) 2013-06-17
SMT201600050B (it) 2016-04-29
ES2787044T3 (es) 2020-10-14
IL256110B (en) 2018-08-30
EA032139B1 (ru) 2019-04-30
PL2632954T3 (pl) 2016-05-31
PT3018145T (pt) 2018-05-17
KR101889995B1 (ko) 2018-08-20
CN103459425B (zh) 2015-11-25
HUE037786T2 (hu) 2018-09-28
IL225924A0 (en) 2013-06-27
NZ609201A (en) 2015-01-30
ME02311B (me) 2016-06-20
DK2632954T3 (en) 2016-02-01
PL2632954T5 (pl) 2021-11-02
US20160208001A1 (en) 2016-07-21
EP3018145A1 (en) 2016-05-11
JP5997168B2 (ja) 2016-09-28
CN105251003A (zh) 2016-01-20
ES2675299T3 (es) 2018-07-10
SMT201800319T1 (it) 2018-07-17
SI3412687T1 (sl) 2020-07-31
CA2815119C (en) 2023-01-10
WO2012055961A1 (en) 2012-05-03
HRP20151444T4 (hr) 2021-08-20
JP2013540799A (ja) 2013-11-07
RS54525B1 (sr) 2016-06-30
MY163057A (en) 2017-08-15
HK1188229A1 (en) 2014-04-25
CY1120227T1 (el) 2018-12-12
AU2011322581A1 (en) 2013-05-09
HRP20180882T1 (hr) 2018-07-27
DK2632954T4 (da) 2021-08-09
IL260774B (en) 2019-02-28
NZ701715A (en) 2016-05-27
SI2632954T2 (sl) 2021-11-30
NZ719768A (en) 2021-07-30
PT2632954E (pt) 2016-02-03
RS54525B2 (sr) 2021-08-31
SI3018145T1 (en) 2018-08-31
JP2016164192A (ja) 2016-09-08
CN103459425A (zh) 2013-12-18
IL256110A (en) 2018-02-28
CY1117155T1 (el) 2017-04-05
RS57260B1 (sr) 2018-08-31
ES2563439T3 (es) 2016-03-15
EP3412687B1 (en) 2020-03-18
CA2815119A1 (en) 2012-05-03
IL225924A (en) 2017-12-31
TR201808019T4 (tr) 2018-06-21
MA34619B1 (fr) 2013-10-02
LT3018145T (lt) 2018-05-10
PL3018145T3 (pl) 2018-09-28
EP2632954B1 (en) 2015-11-25
JP6254220B2 (ja) 2017-12-27
US9192665B2 (en) 2015-11-24
US10696744B2 (en) 2020-06-30
SI2632954T1 (sl) 2016-02-29
KR20140019298A (ko) 2014-02-14
CN105251003B (zh) 2019-08-02

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