LT4230B - Novel cell systems having specific interaction of peptide binding pairs - Google Patents

Novel cell systems having specific interaction of peptide binding pairs Download PDF

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Publication number
LT4230B
LT4230B LT97-004A LT97004A LT4230B LT 4230 B LT4230 B LT 4230B LT 97004 A LT97004 A LT 97004A LT 4230 B LT4230 B LT 4230B
Authority
LT
Lithuania
Prior art keywords
peptide
host cell
cell
protein
binding
Prior art date
Application number
LT97-004A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT97004A (en
Inventor
Kathleen H Young
Bradley A Ozenberger
Original Assignee
American Cyanamid Company A Ma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company A Ma filed Critical American Cyanamid Company A Ma
Publication of LT97004A publication Critical patent/LT97004A/xx
Publication of LT4230B publication Critical patent/LT4230B/lt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mobile Radio Communication Systems (AREA)
LT97-004A 1994-06-14 1997-01-13 Novel cell systems having specific interaction of peptide binding pairs LT4230B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/259,609 US5989808A (en) 1994-06-14 1994-06-14 Identification of compounds affecting specific interaction of peptide binding pairs

Publications (2)

Publication Number Publication Date
LT97004A LT97004A (en) 1997-07-25
LT4230B true LT4230B (en) 1997-10-27

Family

ID=22985626

Family Applications (1)

Application Number Title Priority Date Filing Date
LT97-004A LT4230B (en) 1994-06-14 1997-01-13 Novel cell systems having specific interaction of peptide binding pairs

Country Status (18)

Country Link
US (3) US5989808A (de)
EP (1) EP0765389B1 (de)
AT (1) ATE245189T1 (de)
AU (1) AU706173B2 (de)
CA (1) CA2195083A1 (de)
DE (1) DE69531302T2 (de)
DK (1) DK0765389T3 (de)
ES (1) ES2202366T3 (de)
GE (1) GEP20022619B (de)
IL (1) IL114118A0 (de)
LT (1) LT4230B (de)
LV (1) LV11906B (de)
NZ (1) NZ287372A (de)
PT (1) PT765389E (de)
RU (1) RU2208646C2 (de)
SI (1) SI9520073B (de)
WO (1) WO1995034646A1 (de)
ZA (1) ZA954892B (de)

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US6891021B2 (en) 1993-02-12 2005-05-10 Board Of Trustees Of The Leland Stanford Junior University Regulated apoptosis
US6972193B1 (en) * 1993-02-12 2005-12-06 Board Of Trustees Of Leland Stanford Junior University Regulated transcription of targeted genes and other biological events
US6770446B1 (en) * 1994-06-14 2004-08-03 Wyeth Cell systems having specific interaction of peptide binding pairs
US5610015A (en) * 1995-03-23 1997-03-11 Wisconsin Alumni Research Foundation System to detect protein-RNA interactions
NZ306767A (en) * 1995-04-11 2000-03-27 Univ Johns Hopkins Method of identifying molecular interactions employing counterselection and at least two hybrid molecules or two hybrid systems
US6171800B1 (en) 1995-06-07 2001-01-09 Biogen, Inc. Method of making and binding CAIP polypeptides
US5837844A (en) * 1995-06-07 1998-11-17 Biogen, Inc. CAIP-like gene family
US6423824B1 (en) 1995-06-07 2002-07-23 Biogen, Inc. CAIP-like gene family
CA2252886C (en) * 1996-04-26 2008-02-12 Massachusetts Institute Of Technology Three-hybrid screening assay
DE29724617U1 (de) * 1996-04-26 2002-06-13 Massachusetts Institute Of Technology, Cambridge, Mass. Drei-Hybrid-Kit zur Molekülauswahl
US6696251B1 (en) 1996-05-31 2004-02-24 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
WO1997049808A1 (en) * 1996-06-27 1997-12-31 Biogen, Inc. The caip-like gene family
FR2761697B1 (fr) * 1997-04-03 1999-05-28 Inst Nat Sante Rech Med Methodes de detection d'interactions entre plusieurs proteines
DE19715683C2 (de) * 1997-04-15 1999-11-11 Max Planck Gesellschaft Neue Reportervektoren für One-Hybrid und Two-Hybrid Systeme
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
EP0977846B1 (de) 1997-04-25 2002-06-19 Wyeth Neuronale mort 1 isoformen
US6479653B1 (en) 1997-08-26 2002-11-12 Ariad Gene Therapeutics, Inc. Compositions and method for regulation of transcription
JP4296608B2 (ja) * 1997-08-27 2009-07-15 田辺三菱製薬株式会社 Pparのアゴニスト及びアンタゴニストのスクリーニング方法
EP1149920A1 (de) * 1997-10-15 2001-10-31 Diversa, Inc. Screening fÜr neue Verbindungen, die biologische Interaktionen regulieren
AU1094699A (en) * 1997-10-15 1999-05-03 Diversa Corporation Screening for novel compounds which regulate biological interactions
US6261842B1 (en) 1997-10-23 2001-07-17 Wisconsin Alumni Research Foundation Microorganism genomics, compositions and methods related thereto
WO1999025739A1 (en) * 1997-11-14 1999-05-27 Roche Diagnostics Corporation Variable region fusion peptides that form effector complexes in the presence of antigen
EP1053347B1 (de) 1998-01-09 2007-02-28 Phylogica Limited Nachweisverfahren für peptide
EP0974649A1 (de) * 1998-06-22 2000-01-26 Universität Zürich Screening-System
US7166475B2 (en) 1999-02-26 2007-01-23 Cyclacel Ltd. Compositions and methods for monitoring the modification state of a pair of polypeptides
GB9907687D0 (en) * 1999-04-01 1999-05-26 Kudos Pharm Ltd Assays methods and means
EP1194756A4 (de) 1999-04-21 2004-12-29 Wyeth Corp Verfahren zur identifikation von modulatoren der inaktivierungvon n-typ-ionenkanälen
JP2004527204A (ja) * 2000-04-24 2004-09-09 ワイエス ペプチド結合対の特異的相互作用を有する新規な細胞系
DE60143959D1 (de) 2000-08-25 2011-03-10 Basf Plant Science Gmbh En kodieren
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
DK1534819T3 (da) 2002-08-21 2010-04-19 Revivicor Inc Griselignende dyr, som mangler enhver ekspression af funktionel alfa-1,3-galactosyltransferase
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
US7285269B2 (en) 2002-12-02 2007-10-23 Amgen Fremont, Inc. Antibodies directed to tumor necrosis factor
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EP1544307A1 (de) * 2003-12-18 2005-06-22 AXXAM S.r.l. Chimärer LAC9 Rezeptor und dessen Verwendungen
BRPI0513826A2 (pt) 2004-07-26 2010-06-22 Dow Global Technologies Inc processo para expressão de proteìna melhorada através de engenharia de cepa
EP3138403A1 (de) 2005-08-09 2017-03-08 Revivicor, Inc. Ctla4-ig exprimierende transgene huftiere und verwendungen davon
AU2007212390A1 (en) * 2006-02-07 2007-08-16 Wyeth Materials and methods for identifying agents that modulate Norrin, Norrin mimetics, and agents identified thereby
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
CN101131363B (zh) * 2007-09-30 2010-12-01 南京大学 一种基于酵母三杂交的小分子化合物检测方法
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STATEN NR ET AL.: "Ligandspecific dimerization of the extracellular domain of the bovine growth hormone receptor.", J. BIOL. CHEM., 1993, pages 18 - 467

Also Published As

Publication number Publication date
PT765389E (pt) 2003-11-28
SI9520073B (sl) 2004-06-30
NZ287372A (en) 1997-11-24
EP0765389B1 (de) 2003-07-16
US6284519B1 (en) 2001-09-04
DK0765389T3 (da) 2003-10-27
LV11906B (en) 1998-06-20
CA2195083A1 (en) 1995-12-21
DE69531302D1 (de) 2003-08-21
WO1995034646A1 (en) 1995-12-21
GEP20022619B (en) 2002-01-25
SI9520073A (sl) 1998-02-28
ES2202366T3 (es) 2004-04-01
ATE245189T1 (de) 2003-08-15
RU2208646C2 (ru) 2003-07-20
AU2606695A (en) 1996-01-05
ZA954892B (en) 1996-01-30
EP0765389A1 (de) 1997-04-02
LV11906A (lv) 1997-12-20
LT97004A (en) 1997-07-25
IL114118A0 (en) 1995-10-31
US6251602B1 (en) 2001-06-26
US5989808A (en) 1999-11-23
AU706173B2 (en) 1999-06-10
DE69531302T2 (de) 2004-04-22

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Owner name: WYETH HOLDINGS CORPORATION, US

Effective date: 20031031

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