LTC3207941I2 - - Google Patents

Info

Publication number
LTC3207941I2
LTC3207941I2 LTPA2021507C LTPA2021507C LTC3207941I2 LT C3207941 I2 LTC3207941 I2 LT C3207941I2 LT PA2021507 C LTPA2021507 C LT PA2021507C LT PA2021507 C LTPA2021507 C LT PA2021507C LT C3207941 I2 LTC3207941 I2 LT C3207941I2
Authority
LT
Lithuania
Application number
LTPA2021507C
Original Assignee
Scott & White Memorial Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scott & White Memorial Hospital filed Critical Scott & White Memorial Hospital
Publication of LTPA2021507I1 publication Critical patent/LTPA2021507I1/lt
Publication of LTC3207941I2 publication Critical patent/LTC3207941I2/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/202—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTPA2021507C 2006-09-07 2021-05-12 LTC3207941I2 (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84347106P 2006-09-07 2006-09-07
US93277207P 2007-06-01 2007-06-01
PCT/US2007/019481 WO2008030539A2 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
EP07837840.3A EP2063907B1 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates

Publications (2)

Publication Number Publication Date
LTPA2021507I1 LTPA2021507I1 (lt) 2021-06-10
LTC3207941I2 true LTC3207941I2 (lt) 2022-10-10

Family

ID=39157851

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17151480.5T LT3207941T (lt) 2006-09-07 2007-09-07 Būdai ir kompozicijos difterijos toksino ir interleukino 3 konjugatų pagrindu
LTPA2021507C LTC3207941I2 (lt) 2006-09-07 2021-05-12

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP17151480.5T LT3207941T (lt) 2006-09-07 2007-09-07 Būdai ir kompozicijos difterijos toksino ir interleukino 3 konjugatų pagrindu

Country Status (17)

Country Link
US (7) US7763242B2 (lt)
EP (4) EP2063907B1 (lt)
JP (7) JP5550905B2 (lt)
AU (1) AU2007293047B2 (lt)
CA (5) CA3153438C (lt)
CY (3) CY1119654T1 (lt)
DK (2) DK2063907T3 (lt)
ES (3) ES2781402T7 (lt)
FR (1) FR21C1017I2 (lt)
HU (2) HUE048356T2 (lt)
LT (2) LT3207941T (lt)
LU (1) LUC00206I2 (lt)
NL (1) NL301103I2 (lt)
PL (2) PL3207941T6 (lt)
PT (1) PT3207941T (lt)
SI (1) SI3207941T1 (lt)
WO (1) WO2008030539A2 (lt)

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WO2010027802A2 (en) 2008-08-25 2010-03-11 New York University Methods for treating diabetic wounds
US20110171219A1 (en) * 2008-09-19 2011-07-14 Fahar Merchant Treating cancer stem cells using targeted cargo proteins
AU2011217728B2 (en) * 2010-02-17 2013-03-14 Csl Limited Compositions and methods for targeting type 1 interferon producing cells
EP2582382B1 (en) 2010-06-17 2017-04-19 New York University Cosmetic uses and applications of calreticulin
WO2012019061A2 (en) 2010-08-05 2012-02-09 Stem Centrx, Inc. Novel effectors and methods of use
CA2809369A1 (en) 2010-08-27 2012-03-01 Stem Centrx, Inc. Notum protein modulators and methods of use
BR112013005116A2 (pt) 2010-09-03 2019-09-24 Stem Centrx Inc moduladores e métodos de uso
MX356400B (es) 2010-12-08 2018-05-28 Abbvie Stemcentrx Llc Moduladores novedosos y metodos de uso.
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
EP3854413A1 (en) 2011-07-06 2021-07-28 GlaxoSmithKline Biologicals SA Immunogenic combination compositions and uses thereof
US20130058947A1 (en) 2011-09-02 2013-03-07 Stem Centrx, Inc Novel Modulators and Methods of Use
EP3093294A1 (en) 2012-02-24 2016-11-16 Stemcentrx, Inc. Dll3 modulators and methods of use
KR102099073B1 (ko) 2012-02-24 2020-04-10 애브비 스템센트알엑스 엘엘씨 항 ｓｅｚ6 항체들 및 사용 방법
RU2019109456A (ru) 2013-02-22 2019-04-10 ЭББВИ СТЕМСЕНТРКС ЭлЭлСи Новые конъюгаты антител и их применения
WO2015031698A1 (en) 2013-08-28 2015-03-05 Stem Centrx, Inc. Site-specific antibody conjugation methods and compositions
JP2016538318A (ja) 2013-08-28 2016-12-08 ステムセントリックス， インコーポレイテッド 新規ｓｅｚ６モジュレーターおよび使用方法
CN105764511B (zh) 2013-10-04 2019-01-11 艾普托斯生物科学公司 用于治疗癌症的组合物和方法
PE20160870A1 (es) 2013-11-06 2016-09-09 Abbvie Stemcentrx Llc Anticuerpos anti-claudina novedosos y metodos de uso
KR20160097336A (ko) 2013-12-12 2016-08-17 스템센트알엑스 인코포레이티드 신규 항-ｄｐｅｐ3 항체 및 이의 사용 방법
KR20170008202A (ko) 2014-02-21 2017-01-23 애브비 스템센트알엑스 엘엘씨 흑색종에 사용하기 위한 항-ｄｌｌ3 항체 및 약물 접합체
HRP20210292T1 (hr) 2014-04-30 2021-04-16 Pfizer Inc. Anti-ptk7 protutijelo-lijek konjugati
TW201617368A (zh) 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗ｍｆｉ２抗體及使用方法
WO2017184942A1 (en) 2016-04-21 2017-10-26 Abbvie Stemcentrx Llc Novel anti-bmpr1b antibodies and methods of use
CN107793481A (zh) * 2016-08-31 2018-03-13 南京传奇生物科技有限公司 一种靶向人cd123的嵌合受体配体及其应用
JP2021501203A (ja) 2017-10-30 2021-01-14 アプトース バイオサイエンシズ インコーポレイテッド がん治療用のアリールイミダゾール
WO2019210179A1 (en) 2018-04-27 2019-10-31 Stemline Therapeutics, Inc. Methods of treating an autoimmune disease with a human interleukin-3 (il-3)-diphtheria toxin conjugate (dt-il3)
EP3802834A4 (en) * 2018-05-30 2022-08-03 The Governing Council of the University of Toronto METHODS AND KITS FOR IDENTIFYING A PROTEIN RELATED TO RECEPTOR-LIGAND INTERACTIONS
CN113329752A (zh) 2018-10-31 2021-08-31 斯坦林治疗公司 用白喉毒素-人白细胞介素-3缀合物与其它药剂组合治疗骨髓增生性肿瘤的组合治疗方法
WO2020112642A1 (en) 2018-11-30 2020-06-04 Stemline Therapeutics, Inc. Improved methods of treating myeloproliferative neoplasms with a diphtheria toxin-human interleukin-3 conjugate
US20220411880A1 (en) * 2019-11-21 2022-12-29 Inserm (Institut National De La Santéet De La Recherche Médicale) Methods and compositions for diagnosing and treating chronic myelomonocytic leukemia (cmml)
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AU2014201901B2 (en) 2006-09-07 2016-05-05 Scott & White Healthcare Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
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Also Published As

Publication number Publication date
JP2024088720A (ja) 2024-07-02
EP3520806B1 (en) 2024-03-20
DK3207941T6 (da) 2020-11-09
JP2018135378A (ja) 2018-08-30
EP3207941B3 (en) 2020-08-19
PL2063907T3 (pl) 2018-06-29
US12180257B2 (en) 2024-12-31
JP2016155830A (ja) 2016-09-01
EP4414036A3 (en) 2024-10-09
US8470307B2 (en) 2013-06-25
CA3007075C (en) 2019-10-15
PL3207941T6 (pl) 2020-11-16
CA3007075A1 (en) 2008-03-13
CA3153438A1 (en) 2008-03-13
SI3207941T1 (sl) 2020-08-31
PL3207941T3 (pl) 2020-07-27
JP2014144967A (ja) 2014-08-14
EP3207941A1 (en) 2017-08-23
WO2008030539A3 (en) 2009-04-09
DK3207941T3 (da) 2020-03-30
CY1123035T1 (el) 2021-09-14
US9181317B2 (en) 2015-11-10
ES2781402T3 (es) 2020-09-01
JP5902223B2 (ja) 2016-04-13
US20160024167A1 (en) 2016-01-28
AU2007293047A1 (en) 2008-03-13
US20220235108A1 (en) 2022-07-28
JP6336500B2 (ja) 2018-06-06
NL301103I1 (nl) 2021-06-17
US20080138313A1 (en) 2008-06-12
EP2063907B1 (en) 2017-08-09
FR21C1017I2 (fr) 2022-04-22
CY2021011I1 (el) 2021-10-15
US11130792B2 (en) 2021-09-28
CA2923381A1 (en) 2008-03-13
JP2010502712A (ja) 2010-01-28
PT3207941T (pt) 2020-04-02
US10259853B2 (en) 2019-04-16
LTPA2021507I1 (lt) 2021-06-10
CA3153438C (en) 2024-03-12
LT3207941T (lt) 2020-04-10
US9631006B2 (en) 2017-04-25
HUE048356T2 (hu) 2020-07-28
NL301103I2 (nl) 2021-08-02
ES2646545T3 (es) 2017-12-14
JP2020079260A (ja) 2020-05-28
CY1119654T1 (el) 2019-07-10
EP3207941B1 (en) 2019-12-25
WO2008030539A2 (en) 2008-03-13
US20190169251A1 (en) 2019-06-06
CA2698595C (en) 2016-07-26
EP4414036A2 (en) 2024-08-14
JP6654660B2 (ja) 2020-02-26
CA3053981C (en) 2022-07-12
CY2021011I2 (el) 2021-10-15
FR21C1017I1 (lt) 2021-07-02
AU2007293047B2 (en) 2014-01-09
CA3053981A1 (en) 2008-03-13
HUS2100013I1 (hu) 2021-05-28
JP2022065089A (ja) 2022-04-26
US7763242B2 (en) 2010-07-27
ES2987072T3 (es) 2024-11-13
EP2063907A2 (en) 2009-06-03
EP3520806A1 (en) 2019-08-07
EP2063907A4 (en) 2011-08-31
US20180022788A1 (en) 2018-01-25
DK2063907T3 (da) 2017-11-13
ES2781402T7 (es) 2021-06-09
LUC00206I2 (lt) 2022-10-07
US20130315860A1 (en) 2013-11-28
CA2698595A1 (en) 2008-03-13
US20090232767A1 (en) 2009-09-17
JP5550905B2 (ja) 2014-07-16

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