LTIP1775A - Novel heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same - Google Patents

Novel heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same

Info

Publication number: LTIP1775A
Authority: LT; Lithuania
Prior art keywords: group; hydrogen atom; sulfur; pharmaceutical compositions; compounds
Prior art date: 1989-07-11

Application number

LTIP1775A

Other languages

English (en)

Inventor

Karoly Nador

Pal Scheiber

Erzsebet Szelecsenyi

Bela Molnar

Laszlo Szporny

Bela Kiss

Egon Karpati

Eva Palosi

Dora Groo

Istvan Laszlovszky

Zsolt Szombathelyi

Adam Sarkadi

Aniko Gere

Mihaly Bodo

Katalin Csomor

Judit Laszy

Zsolt Szentirmai

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-11

Filing date

1994-01-14

Publication date

1995-07-25

1994-01-14 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1995-07-25 Publication of LTIP1775A publication Critical patent/LTIP1775A/xx

Links

150000002391 heterocyclic compounds Chemical class 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title 2
JLQNHALFVCURHW-UHFFFAOYSA-N cyclooctasulfur Chemical compound S1SSSSSSS1 JLQNHALFVCURHW-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229910052757 nitrogen Inorganic materials 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
PFRUBEOIWWEFOL-UHFFFAOYSA-N [N].[S] Chemical compound [N].[S] PFRUBEOIWWEFOL-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000000141 anti-hypoxic effect Effects 0.000 abstract 1
125000005418 aryl aryl group Chemical group 0.000 abstract 1
230000002490 cerebral effect Effects 0.000 abstract 1
125000005059 halophenyl group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Thiazole And Isothizaole Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Adhesives Or Adhesive Processes (AREA)

LTIP1775A 1989-07-11 1994-01-14 Novel heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same LTIP1775A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU893474A HU204040B (en)	1989-07-11	1989-07-11	Process for producing new thiazoles and thiazines and pharmaceutical compositions comprising same

Publications (1)

Publication Number	Publication Date
LTIP1775A true LTIP1775A (en)	1995-07-25

Family

ID=10964168

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTIP1775A LTIP1775A (en)	1989-07-11	1994-01-14	Novel heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same

Country Status (24)

Country	Link
US (1)	US5096902A (ja)
EP (1)	EP0411775B1 (ja)
JP (1)	JPH0348670A (ja)
KR (1)	KR950003496B1 (ja)
CN (1)	CN1028229C (ja)
AT (1)	ATE135349T1 (ja)
AU (1)	AU629660B2 (ja)
CA (1)	CA2020805A1 (ja)
DD (1)	DD297973A5 (ja)
DE (1)	DE69025819T2 (ja)
FI (1)	FI903473A7 (ja)
HR (1)	HRP920775A2 (ja)
HU (2)	HU204040B (ja)
IE (1)	IE902499A1 (ja)
IL (1)	IL95018A (ja)
LT (1)	LTIP1775A (ja)
LV (1)	LV10090B (ja)
NO (1)	NO903078L (ja)
NZ (1)	NZ234440A (ja)
PL (2)	PL165110B1 (ja)
PT (1)	PT94653A (ja)
RU (1)	RU1833377C (ja)
YU (1)	YU47797B (ja)
ZA (1)	ZA905406B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2088965T3 (es) *	1989-04-07	1996-10-01	Lilly Co Eli	Derivados de rodanina aril-sustituidos.
US5458793A (en) *	1993-05-13	1995-10-17	The Lubrizol Corporation	Compositions useful as additives for lubricants and liquid fuels

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU78421A1 (fr) *	1977-10-31	1979-06-01	Zyma Sa	Procede de preparation de nouveaux composes thiazolidiniques
US4656286A (en) *	1984-08-27	1987-04-07	Polaroid Corporation, Patent Dept.	Aminoethanethiol and thiazolidine compounds
US4652649A (en) *	1985-02-20	1987-03-24	United Pharmaceuticals, Inc.	Anti-spasmodic agents having a ring in the main chain
HU198012B (en) *	1987-07-03	1989-07-28	Richter Gedeon Vegyeszet	Process for producing cyclic amino-acid derivatives and pharmaceutical compositions containing them
CA2004028C (en) *	1988-12-08	1998-09-22	Motoki Torizuka	Condensed benzene derivative

1989
- 1989-07-11 HU HU893474A patent/HU204040B/hu not_active IP Right Cessation
1990
- 1990-04-12 US US07/509,473 patent/US5096902A/en not_active Expired - Fee Related
- 1990-07-10 PL PL90300985A patent/PL165110B1/pl unknown
- 1990-07-10 CN CN90104518A patent/CN1028229C/zh not_active Expired - Fee Related
- 1990-07-10 EP EP90307527A patent/EP0411775B1/en not_active Expired - Lifetime
- 1990-07-10 FI FI903473A patent/FI903473A7/fi not_active Application Discontinuation
- 1990-07-10 ZA ZA905406A patent/ZA905406B/xx unknown
- 1990-07-10 RU SU904830514A patent/RU1833377C/ru active
- 1990-07-10 IL IL9501890A patent/IL95018A/en not_active IP Right Cessation
- 1990-07-10 IE IE249990A patent/IE902499A1/en not_active Application Discontinuation
- 1990-07-10 KR KR90010436A patent/KR950003496B1/ko not_active Expired - Lifetime
- 1990-07-10 AU AU58815/90A patent/AU629660B2/en not_active Ceased
- 1990-07-10 DE DE69025819T patent/DE69025819T2/de not_active Expired - Fee Related
- 1990-07-10 NZ NZ234440A patent/NZ234440A/xx unknown
- 1990-07-10 CA CA002020805A patent/CA2020805A1/en not_active Abandoned
- 1990-07-10 PL PL90285992A patent/PL165125B1/pl unknown
- 1990-07-10 DD DD90342666A patent/DD297973A5/de not_active IP Right Cessation
- 1990-07-10 YU YU133390A patent/YU47797B/sh unknown
- 1990-07-10 NO NO90903078A patent/NO903078L/no unknown
- 1990-07-10 PT PT94653A patent/PT94653A/pt not_active Application Discontinuation
- 1990-07-10 AT AT90307527T patent/ATE135349T1/de not_active IP Right Cessation
- 1990-07-11 JP JP2181698A patent/JPH0348670A/ja active Pending
1992
- 1992-10-01 HR HRP920775AA patent/HRP920775A2/hr not_active Application Discontinuation
- 1992-12-30 LV LVP-92-685A patent/LV10090B/lv unknown
1994
- 1994-01-14 LT LTIP1775A patent/LTIP1775A/xx not_active Application Discontinuation
- 1994-10-12 HU HU94P/P00038P patent/HU210074A9/hu unknown

Also Published As

Publication number	Publication date
US5096902A (en)	1992-03-17
ZA905406B (en)	1991-04-24
RU1833377C (en)	1993-08-07
JPH0348670A (ja)	1991-03-01
HRP920775A2 (hr)	1994-04-30
CN1028229C (zh)	1995-04-19
CA2020805A1 (en)	1991-01-12
KR950003496B1 (en)	1995-04-13
NO903078D0 (no)	1990-07-10
YU133390A (sh)	1992-09-07
PL285992A1 (en)	1991-02-25
ATE135349T1 (de)	1996-03-15
FI903473A0 (fi)	1990-07-10
YU47797B (sr)	1996-01-09
FI903473A7 (fi)	1991-01-12
PL165125B1 (pl)	1994-11-30
EP0411775B1 (en)	1996-03-13
EP0411775A1 (en)	1991-02-06
HUT55768A (en)	1991-06-28
NO903078L (no)	1991-01-14
DE69025819T2 (de)	1996-09-05
HU210074A9 (en)	1995-02-28
IL95018A (en)	1995-05-26
CN1049159A (zh)	1991-02-13
AU5881590A (en)	1991-01-17
IE902499A1 (en)	1991-02-13
LV10090B (en)	1995-02-20
HU204040B (en)	1991-11-28
PT94653A (pt)	1991-04-18
DE69025819D1 (de)	1996-04-18
LV10090A (lv)	1994-05-10
AU629660B2 (en)	1992-10-08
IL95018A0 (en)	1991-06-10
PL165110B1 (pl)	1994-11-30
DD297973A5 (de)	1992-01-30
NZ234440A (en)	1991-09-25
KR910002819A (ko)	1991-02-26

Legal Events

Date	Code	Title	Description
1996-02-26	FD9A	Withdrawn applications	Free format text: 951221

Publication	Publication Date	Title
HU908443D0 (en)	1991-07-29	Process for the production of peptides
HU913883D0 (en)	1992-02-28	N-(iodo-propargyl-oxi-carbonyl)amino acid esthers of anti-microbial effect
NZ236026A (en)	1992-03-26	6-phenyl-, pyridyl-, furanyl- and thienyl- substituted 5,6-dihydroimidazo (2,1-b) thiazole derivatives; preparatory processes, intermediates therefor and pharmaceutical compositions
EP0270093A3 (en)	1989-12-27	Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties
AU629660B2 (en)	1992-10-08	Novel heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same
ATE69448T1 (de)	1991-11-15	Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
YU43701B (en)	1989-10-31	Process for preparing new amidinic derivatives of 2-substituted 4-phenyl-imidazole
IL67464A (en)	1986-08-31	N,n-disubstituted alkenamides and phenylalkenamides,their production and pharmaceutical compositions containing them
HUT53487A (en)	1990-11-28	Fungicide compositions containing nitrogen-containing heterocyclic compounds as active components and process for producing the active components