LU86258A1 - Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique - Google Patents

Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique Download PDF

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Publication number
LU86258A1
LU86258A1 LU86258A LU86258A LU86258A1 LU 86258 A1 LU86258 A1 LU 86258A1 LU 86258 A LU86258 A LU 86258A LU 86258 A LU86258 A LU 86258A LU 86258 A1 LU86258 A1 LU 86258A1
Authority
LU
Luxembourg
Prior art keywords
radical
formula
compounds according
acid
adamantyl
Prior art date
Application number
LU86258A
Other languages
English (en)
French (fr)
Inventor
Shroot Braham
Eustache Jacques
Bernardon Jean-Michel
Original Assignee
Rech Dermatologiques C I R D S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rech Dermatologiques C I R D S filed Critical Rech Dermatologiques C I R D S
Priority to LU86258A priority Critical patent/LU86258A1/fr
Priority to IE870121A priority patent/IE870121L/xx
Priority to DE8787400134T priority patent/DE3783922T2/de
Priority to JP62013274A priority patent/JP2520120B2/ja
Priority to DE198787400134T priority patent/DE232199T1/de
Priority to EP87400134A priority patent/EP0232199B1/fr
Priority to CA000527731A priority patent/CA1315201C/fr
Priority to NZ218991A priority patent/NZ218991A/en
Priority to DK029187A priority patent/DK172063B1/da
Priority to CA000527732A priority patent/CA1337344C/fr
Priority to AU67806/87A priority patent/AU597329B2/en
Priority to ZA87435A priority patent/ZA87435B/xx
Priority to US07/005,727 priority patent/US4927928A/en
Publication of LU86258A1 publication Critical patent/LU86258A1/fr
Priority to US07/483,625 priority patent/US5212203A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/445Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
LU86258A 1986-01-21 1986-01-21 Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique LU86258A1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
LU86258A LU86258A1 (fr) 1986-01-21 1986-01-21 Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
NZ218991A NZ218991A (en) 1986-01-21 1987-01-20 Aromatic benzamido derivatives, process for preparing them, and pharmaceutical and cosmetic compositions thereof
DK029187A DK172063B1 (da) 1986-01-21 1987-01-20 Benzamido-forbindelser, deres fremstilling, anvendelse deraf til fremstilling af præparat og præparater deraf
JP62013274A JP2520120B2 (ja) 1986-01-21 1987-01-20 芳香族ベンズアミド化合物、その製法、ひとおよび動物医薬、並びに化粧品
DE198787400134T DE232199T1 (de) 1986-01-21 1987-01-20 Aromatische benzamido-verbindungen, verfahren zu ihrer herstellung und ihre verwendung in human- oder tiermedizin und in der kosmetik.
EP87400134A EP0232199B1 (fr) 1986-01-21 1987-01-20 Composés benzamido aromatiques, leur procédé de préparation et leur utilisation en médecine humaine ou vétérinaire et en cosmétique
CA000527731A CA1315201C (fr) 1986-01-21 1987-01-20 Compositions pharmaceutiques a base de composes benzamido aromatiques
IE870121A IE870121L (en) 1986-01-21 1987-01-20 "aromatic benzamido compounds, a method for their¹preparation and their use in human and veterinary medicine¹and in cosmetics"
DE8787400134T DE3783922T2 (de) 1986-01-21 1987-01-20 Aromatische benzamido-verbindungen, verfahren zu ihrer herstellung und ihre verwendung in human- oder tiermedizin und in der kosmetik.
CA000527732A CA1337344C (fr) 1986-01-21 1987-01-20 Composes benzamido aromatique, leur procede de preparation et leur utilisation en cosmetique
AU67806/87A AU597329B2 (en) 1986-01-21 1987-01-20 Benzamido-aromatic derivatives, process for their preparation and their use in human or veterinary medicine and in cosmetics
ZA87435A ZA87435B (en) 1986-01-21 1987-01-21 Aromatic benzamido compounds,a method for their preparation and their use in human and veterinary medicine and in cosmetics
US07/005,727 US4927928A (en) 1986-01-21 1987-01-21 Aromatic benzamido compounds, their preparation and their use in human or veterinary medicine or in cosmetic preparations
US07/483,625 US5212203A (en) 1986-01-21 1990-02-23 Aromatic benzamido compounds; their preparation and their use in human or veterinary medicine or in cosmetic preparations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU86258 1986-01-21
LU86258A LU86258A1 (fr) 1986-01-21 1986-01-21 Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique

Publications (1)

Publication Number Publication Date
LU86258A1 true LU86258A1 (fr) 1987-09-03

Family

ID=19730618

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86258A LU86258A1 (fr) 1986-01-21 1986-01-21 Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique

Country Status (11)

Country Link
US (1) US4927928A (da)
EP (1) EP0232199B1 (da)
JP (1) JP2520120B2 (da)
AU (1) AU597329B2 (da)
CA (2) CA1315201C (da)
DE (2) DE3783922T2 (da)
DK (1) DK172063B1 (da)
IE (1) IE870121L (da)
LU (1) LU86258A1 (da)
NZ (1) NZ218991A (da)
ZA (1) ZA87435B (da)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742083A (en) * 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
US4939133A (en) * 1985-10-01 1990-07-03 Warner-Lambert Company N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade
US5212203A (en) * 1986-01-21 1993-05-18 Centre International De Recherches Dermatogologiques (C.I.R.D.) Aromatic benzamido compounds; their preparation and their use in human or veterinary medicine or in cosmetic preparations
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
LU87039A1 (fr) * 1987-11-04 1989-06-14 Oreal Esters biaromatiques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
JPH0742259B2 (ja) * 1988-12-23 1995-05-10 保土谷化学工業株式会社 ベンズアミド誘導体
IT1232252B (it) * 1989-02-22 1992-01-28 Rotta Research Lab Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
FR2649977B1 (fr) * 1989-07-18 1991-10-04 Cird Esters bi-aromatiques, leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
CA2020887A1 (en) * 1989-07-28 1991-01-29 Michael Klaus Aromatic carboxylic amides
GB8921792D0 (en) * 1989-09-27 1989-11-08 May & Baker Ltd New compositions of matter
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
GB9017710D0 (en) * 1990-08-13 1990-09-26 May & Baker Ltd New compositions of matter
US5698711A (en) * 1991-01-28 1997-12-16 Rhone-Poulenc Rorer Limited Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- or heteroatom-containing linking group
CH685875A5 (fr) * 1991-04-26 1995-10-31 Pierre Baudet Les N-phényl-benzamides protecteurs contre les effets nocifs de la lumière ultra-violette
US5869067A (en) * 1991-05-15 1999-02-09 Centre International De Recherches Dermatologiques Galderma (Cird Galderma) Bi-aromatic compounds and pharmaceutical and cosmetic compositions
FR2676440B1 (fr) * 1991-05-15 1993-07-30 Cird Galderma Nouveaux composes aromatiques derives d'imine, leur procede de preparation et leur utilisation en medecine humaine et veterinaire ainsi qu'en cosmetique.
US5753239A (en) * 1991-05-15 1998-05-19 Centre International De Recherches Dematologiques Galderma (Cird Galderma) Bi-aromatic compounds and pharmaceutical and cosmetic compositions
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
DE4307976A1 (de) * 1993-03-15 1994-09-22 Beiersdorf Ag Neue Verwendung von Aknemitteln
EP0619116A3 (en) * 1993-04-05 1994-11-23 Hoechst Japan Use of synthetic retinoids for osteopathy.
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6461643B2 (en) 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5472983A (en) * 1994-04-14 1995-12-05 Centaur Pharmaceuticals, Inc. Benzamide-containing pharmaceutical compositions
US6133326A (en) 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO1997036480A1 (en) * 1996-03-29 1997-10-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5756548A (en) * 1995-04-03 1998-05-26 Centaur Pharmaceuticals, Inc. Acetamidobenzamide compounds for neurodegenerative disorders
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
WO1997010197A1 (en) * 1995-09-11 1997-03-20 Emisphere Technologies, Inc. METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
FR2741878B1 (fr) * 1995-12-01 1998-01-09 Cird Galderma Composes biaromatiques portant un groupement adamantyl en ortho, compositions pharmaceutiques et cosmetiques les contenant et utilisations
US5955506A (en) * 1996-04-03 1999-09-21 Centaur Pharmaceuticals, Inc. Benzamides for neurodegenerative disorder treatment
AU3828597A (en) 1996-06-14 1998-01-07 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US6303645B1 (en) 1998-05-22 2001-10-16 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
JP2002516276A (ja) 1998-05-22 2002-06-04 アバニール・ファーマシューティカルズ IgEのモジュレータとしてのベンゾイミダゾール誘導体
US6919366B2 (en) 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6369091B1 (en) 1998-05-22 2002-04-09 Avanir Pharmaceuticals Benzimidazole analogs as down-regulators of IgE
US6991798B1 (en) 1998-08-07 2006-01-31 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CA2339765C (en) * 1998-08-07 2009-04-28 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
NZ534409A (en) * 1999-04-05 2006-03-31 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) * 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
ES2298168T3 (es) * 1999-12-16 2008-05-16 Emisphere Technologies, Inc. Compuestos y composiciones para suministrar agentes activos.
JP4879433B2 (ja) * 2000-01-13 2012-02-22 エミスフェアー・テクノロジーズ・インク 活性剤を送達するための化合物および組成物
US7351741B2 (en) * 2000-06-29 2008-04-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
KR100407640B1 (ko) * 2000-12-19 2003-12-01 주식회사 태평양 신규한 디페닐 아미드 유도체, 그의 제조방법 및 이를포함하는 약학 및 화장료 조성물
DE60221804T2 (de) 2001-03-12 2008-05-15 Avanir Pharmaceuticals, San Diego Benzimidazolderivate zur ige-modulierung und zellproliferationshemmung
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2002344453B2 (en) * 2002-11-05 2009-04-09 Lead Chemical Co.,Ltd. Compound protecting against ultraviolet
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
KR100680584B1 (ko) * 2005-08-19 2007-02-08 (주)아모레퍼시픽 히드록시벤즈아미드 화합물 및 그 제조방법, 및 이를유효성분으로 함유하는 화장료 조성물
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
KR101349187B1 (ko) 2006-12-05 2014-01-10 (주)아모레퍼시픽 지방대사 이상질환의 치료 및 예방용 약학 조성물
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2931661B1 (fr) 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
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US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
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WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
KR101604053B1 (ko) * 2011-08-05 2016-03-16 (주)아모레퍼시픽 신규 벤조산아미드 화합물
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US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2017050870A1 (en) * 2015-09-22 2017-03-30 Sabic Global Technologies B.V. Synthesis of substituted amidobenzoate compounds, the compounds obtained and the use thereof as phthalate free internal electron donor for polymerization of olefins
CN106905184B (zh) * 2017-03-05 2019-03-29 北京化工大学 含有苯甲酰胺基团的氮芥类化合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5247453B2 (da) * 1973-04-23 1977-12-02
DE2500157C2 (de) * 1975-01-03 1983-09-15 Hoechst Ag, 6230 Frankfurt N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung
LU85544A1 (fr) * 1984-09-19 1986-04-03 Cird Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique
HU201300B (en) * 1985-03-16 1990-10-28 Wellcome Found Process for production of derivatives of aryl and medical compositions containing them as active substance
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique

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AU6780687A (en) 1987-07-23
AU597329B2 (en) 1990-05-31
CA1315201C (fr) 1993-03-30
DK172063B1 (da) 1997-10-06
DE3783922D1 (de) 1993-03-18
US4927928A (en) 1990-05-22
NZ218991A (en) 1990-01-29
CA1337344C (fr) 1995-10-17
IE870121L (en) 1987-07-21
DE3783922T2 (de) 1993-09-02
DE232199T1 (de) 1988-11-03
EP0232199B1 (fr) 1993-02-03
EP0232199A3 (en) 1989-12-27
ZA87435B (en) 1987-09-30
DK29187A (da) 1987-07-22
JPS62190154A (ja) 1987-08-20
DK29187D0 (da) 1987-01-20
EP0232199A2 (fr) 1987-08-12
JP2520120B2 (ja) 1996-07-31

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