LU86600A1 - Produits d'echange entre un aminodisulfure et un thiol - Google Patents

Produits d'echange entre un aminodisulfure et un thiol Download PDF

Info

Publication number
LU86600A1
LU86600A1 LU86600A LU86600A LU86600A1 LU 86600 A1 LU86600 A1 LU 86600A1 LU 86600 A LU86600 A LU 86600A LU 86600 A LU86600 A LU 86600A LU 86600 A1 LU86600 A1 LU 86600A1
Authority
LU
Luxembourg
Prior art keywords
compound
identified
compound according
amino
substituted
Prior art date
Application number
LU86600A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU86600A1 publication Critical patent/LU86600A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU86600A 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol LU86600A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/781,076 US4866180A (en) 1984-02-24 1985-09-23 Amino disulfide thiol exchange products
US78107685 1985-09-23

Publications (1)

Publication Number Publication Date
LU86600A1 true LU86600A1 (fr) 1987-04-02

Family

ID=25121607

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86600A LU86600A1 (fr) 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol

Country Status (10)

Country Link
US (1) US4866180A (es)
KR (1) KR940006629B1 (es)
AT (1) AT394725B (es)
CA (1) CA1288106C (es)
ES (1) ES2001978A6 (es)
FI (1) FI863776A7 (es)
GR (1) GR862416B (es)
LU (1) LU86600A1 (es)
PT (1) PT83418B (es)
ZA (1) ZA866297B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) * 1993-08-26 1997-05-13 Peterson; Dwight M. 2,7-diaminomitosene analogues
ATE427948T1 (de) 2001-04-24 2009-04-15 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
CA2484640C (en) * 2002-05-15 2012-01-17 Endocyte, Inc. Vitamin-mitomycin conjugates
WO2004069159A2 (en) 2003-01-27 2004-08-19 Endocyte, Inc. Vitamin receptor binding drug delivery conjugates
CN101098854B (zh) * 2004-07-23 2012-12-05 恩多塞特公司 二价连接体及其轭合物
CN101175757B (zh) * 2005-03-16 2012-11-14 恩多塞特公司 蝶酸及其缀合物的合成和纯化
BRPI0615354A2 (pt) * 2005-08-19 2011-05-17 Endocyte, Inc. conjugado de liberação de fármaco de ligação de receptor, composição farmacêutica que o compreende, bem como seu uso
EP2382995A3 (en) * 2005-08-19 2013-09-25 Endocyte, Inc. Ligand conjugates of Vinca alkaloids, analogs and derivatives
US20100104626A1 (en) * 2007-02-16 2010-04-29 Endocyte, Inc. Methods and compositions for treating and diagnosing kidney disease
AU2008224988A1 (en) * 2007-03-14 2008-09-18 Endocyte, Inc. Binding ligand linked drug delivery conjugates of tubulysins
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
CN101784565B (zh) 2007-06-25 2014-12-10 恩多塞特公司 含有亲水性间隔区接头的共轭物
CN101909441B (zh) 2007-10-25 2015-05-13 恩多塞特公司 微管蛋白抑制剂及其制备方法
US10080805B2 (en) 2012-02-24 2018-09-25 Purdue Research Foundation Cholecystokinin B receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
BR112015008365A2 (pt) 2012-10-16 2017-07-04 Endocyte Inc composto da fórmula b-l(d)x, ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, composição de forma de dosagem unitária ou dose unitária, composição para tratar um câncer em um paciente, e método para tratar um câncer em um paciente

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (es) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
EP0116208B1 (en) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin analogues
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤

Also Published As

Publication number Publication date
CA1288106C (en) 1991-08-27
ZA866297B (en) 1987-04-29
PT83418B (pt) 1989-05-12
FI863776A0 (fi) 1986-09-18
FI863776L (fi) 1987-03-24
KR870003111A (ko) 1987-04-15
KR940006629B1 (ko) 1994-07-23
FI863776A7 (fi) 1987-03-24
ES2001978A6 (es) 1988-07-01
ATA254886A (de) 1991-11-15
AT394725B (de) 1992-06-10
PT83418A (en) 1986-10-01
US4866180A (en) 1989-09-12
GR862416B (en) 1987-01-26

Similar Documents

Publication Publication Date Title
LU86600A1 (fr) Produits d'echange entre un aminodisulfure et un thiol
EP0280741B1 (en) Mitomycin derivatives
HK1001329B (en) Mitomycin derivatives
US6306849B1 (en) Selected derivatives of K-252a
EP0313874B1 (en) Disulfur analogs of LL-E33288 antitumor agents
LU84843A1 (fr) Amidines
LU85295A1 (fr) Aminodisulfures
US4814445A (en) Process for preparing mitomycin analogs
LU85711A1 (fr) Acylaminomitosanes
CA1291293C (en) Substituted 7-oxomitosanes
JP2991348B2 (ja) ７−（ジフェニルメチル）オキシ−９ａ−メトキシマイトサン並びにその製造及び使用
FR2517680A1 (fr) Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique
BE899380A (fr) Aminodisulfures.
US4927943A (en) Substituted 7-oxomitosanes
US5106840A (en) Method of preparing n-oxo-tetrahydro-beta-carbolines
LU86411A1 (fr) Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.
US5318975A (en) 5-pyrimdineamine derivatives
EP0272063B1 (en) Mitomycin derivatives
EP0294828B1 (en) Mitomycin analogs, a process for preparing them and pharmaceutical compositions
BE896963A (fr) Amidines
EP0412015B1 (fr) Nouveaux dérivés N-(vincristinoyl-23) et N-(noranhydro-5' vinblastinoyl-23) d'acide amino-1 méthylphosphonique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
CA1204770A (en) Fluorinated diaminoalkene derivatives
US5099016A (en) Substituted 7-oxomitosanes
US5097036A (en) Substituted 7-oxomitosanes
CA2502515A1 (fr) Derives de pyrrolo (3,4-c) carbazole et de pyrido (2,3-b) pyrrolo (3,4-e) indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent