LU88811I2 - Liposome daunorubicine optionellement sous forme d'un sel d'addition acide les liposomes comprenant un phospholipide chimiquement pur (pureté>98%) et de zéro à cinquante pourcents en poids de cholestérol par rapport au phospholipide et les liposomes ayant une taille inférieure à 200nm - Google Patents

Liposome daunorubicine optionellement sous forme d'un sel d'addition acide les liposomes comprenant un phospholipide chimiquement pur (pureté>98%) et de zéro à cinquante pourcents en poids de cholestérol par rapport au phospholipide et les liposomes ayant une taille inférieure à 200nm

Info

Publication number: LU88811I2
Authority: LU; Luxembourg
Prior art keywords: liposomes; phospholipid; purity; zero; micellular
Prior art date: 1984-10-22

Application number

LU88811C

Other languages

English (en)

Original Assignee

Nexstar Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-22

Filing date

1985-10-22

Publication date

1996-11-05

1984-10-22 Priority claimed from US06/663,550 external-priority patent/US5441745A/en

1984-10-22 Priority claimed from US06/663,503 external-priority patent/US5435989A/en

1985-10-22 Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc

1996-11-05 Publication of LU88811I2 publication Critical patent/LU88811I2/fr

Links

150000003904 phospholipids Chemical class 0.000 title abstract 3
239000002502 liposome Substances 0.000 title 3
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
235000012000 cholesterol Nutrition 0.000 title 1
STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 title 1
229960000975 daunorubicin Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
239000002245 particle Substances 0.000 abstract 6
206010028980 Neoplasm Diseases 0.000 abstract 2
239000002246 antineoplastic agent Substances 0.000 abstract 2
229940127089 cytotoxic agent Drugs 0.000 abstract 2
239000012216 imaging agent Substances 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
210000001539 phagocyte Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Physics & Mathematics (AREA)
Dispersion Chemistry (AREA)
Optics & Photonics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

LU88811C 1984-10-22 1985-10-22 Liposome daunorubicine optionellement sous forme d'un sel d'addition acide les liposomes comprenant un phospholipide chimiquement pur (pureté>98%) et de zéro à cinquante pourcents en poids de cholestérol par rapport au phospholipide et les liposomes ayant une taille inférieure à 200nm LU88811I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/663,550 US5441745A (en)	1982-03-30	1984-10-22	Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body
US06/663,503 US5435989A (en)	1982-03-30	1984-10-22	Method of targeting a specific location in a body

Publications (1)

Publication Number	Publication Date
LU88811I2 true LU88811I2 (fr)	1996-11-05

Family

ID=27098764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU88811C LU88811I2 (fr)	1984-10-22	1985-10-22	Liposome daunorubicine optionellement sous forme d'un sel d'addition acide les liposomes comprenant un phospholipide chimiquement pur (pureté>98%) et de zéro à cinquante pourcents en poids de cholestérol par rapport au phospholipide et les liposomes ayant une taille inférieure à 200nm

Country Status (11)

Country	Link
EP (1)	EP0179444B1 (fr)
JP (1)	JPH0747533B2 (fr)
KR (1)	KR900004802B1 (fr)
AT (1)	ATE64298T1 (fr)
CA (1)	CA1298548C (fr)
DE (2)	DE3583204D1 (fr)
DK (2)	DK482685D0 (fr)
HK (1)	HK119993A (fr)
IE (1)	IE58659B1 (fr)
LU (1)	LU88811I2 (fr)
NL (1)	NL960020I1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE60901B1 (en) *	1986-08-21	1994-08-24	Vestar Inc	Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics
US5043107A (en) *	1986-08-21	1991-08-27	Vestar Research, Inc.	Preparation small unilamellar vesicles including polyene antifungal antibiotics
IL88076A (en) *	1987-10-28	1993-01-14	Nippon Shinyaku Co Ltd	Fat emulsions as drug carriers
AU598958B2 (en)	1987-11-12	1990-07-05	Vestar, Inc.	Improved amphotericin b liposome preparation
US5648532A (en) *	1993-06-03	1997-07-15	The Regents Of The University Of California	Compositions for boron neutron capture therapy and methods thereof
EP0806969A2 (fr) *	1995-02-09	1997-11-19	Schering Aktiengesellschaft	Liposomes contenant des agents de contraste pour l'imagerie relative au pool sanguin intracardiaque
NO312708B1 (no) *	2000-02-21	2002-06-24	Anticancer Therapeutic Inv Sa	Radioaktive liposomer til terapi
EP1684723A4 (fr) *	2003-11-21	2007-06-20	Fujifilm Corp	Milieu de contraste comprenant des liposomes contenant un compose de chelate hydrophobe
EP1745788A1 (fr) *	2005-07-22	2007-01-24	KTB Tumorforschungsgesellschaft mbH	Acylglycerophospholipides pour le traitement du cancer et de la cachexie
WO2012066896A1 (fr) *	2010-11-19	2012-05-24	Kato Junji	Préparation pharmaceutique combinée

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4310505A (en) *	1979-11-08	1982-01-12	California Institute Of Technology	Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
JPS59122423A (ja) *	1982-12-28	1984-07-14	Green Cross Corp:The	制癌剤含有脂肪乳剤
JPS59163315A (ja) *	1983-03-09	1984-09-14	Mitsui Pharmaceut Inc	カルモフ−ル含有リポソ−ム

1985
- 1985-10-21 DK DK482685A patent/DK482685D0/da not_active Application Discontinuation
- 1985-10-21 IE IE260285A patent/IE58659B1/en not_active IP Right Cessation
- 1985-10-21 CA CA000493488A patent/CA1298548C/fr not_active Expired - Lifetime
- 1985-10-22 DE DE8585113386T patent/DE3583204D1/de not_active Expired - Lifetime
- 1985-10-22 JP JP60236230A patent/JPH0747533B2/ja not_active Expired - Lifetime
- 1985-10-22 EP EP85113386A patent/EP0179444B1/fr not_active Expired - Lifetime
- 1985-10-22 KR KR1019850007773A patent/KR900004802B1/ko not_active Expired
- 1985-10-22 DE DE19675031C patent/DE19675031I2/de active Active
- 1985-10-22 DK DK484585A patent/DK167556B1/da active Protection Beyond IP Right Term
- 1985-10-22 AT AT85113386T patent/ATE64298T1/de active
- 1985-10-22 LU LU88811C patent/LU88811I2/fr unknown
1993
- 1993-11-04 HK HK1199/93A patent/HK119993A/en not_active IP Right Cessation
1996
- 1996-08-09 NL NL960020C patent/NL960020I1/nl unknown

Also Published As

Publication number	Publication date
DK484585D0 (da)	1985-10-22
DE19675031I2 (de)	2008-04-10
JPH0747533B2 (ja)	1995-05-24
CA1298548C (fr)	1992-04-07
HK119993A (en)	1993-11-12
DK167556B1 (da)	1993-11-22
IE852602L (en)	1986-04-22
KR900004802B1 (ko)	1990-07-06
JPS61158932A (ja)	1986-07-18
DK482685D0 (da)	1985-10-21
DK484585A (da)	1986-04-23
EP0179444B1 (fr)	1991-06-12
DE3583204D1 (de)	1991-07-18
IE58659B1 (en)	1993-11-03
EP0179444A3 (en)	1987-08-12
EP0179444A2 (fr)	1986-04-30
ATE64298T1 (de)	1991-06-15
NL960020I1 (nl)	1996-11-01
KR860003514A (ko)	1986-05-26

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