DK484585A - Micellulaere partikelkompositioner, hvori er indkapslet billedtagende og kemoterapeutiske midler for tumorer, og kompositionernes anvendelse - Google Patents

Micellulaere partikelkompositioner, hvori er indkapslet billedtagende og kemoterapeutiske midler for tumorer, og kompositionernes anvendelse Download PDF

Info

Publication number: DK484585A
Authority: DK; Denmark
Prior art keywords: micellular; tumors; compositions; chemotherapeutic agents; encouraged
Prior art date: 1984-10-22

Application number

DK484585A

Other languages

English (en)

Other versions

DK484585D0 (da

DK167556B1 (da

Inventor

Cary Arnett Presant

Richard Thomas Proffitt

Raymond Leo Teplitz

Lawrence Ernest Williams

George Wing-Yiu Tin

Original Assignee

Hope Nat Medical Center

Vestar Research Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-22

Filing date

1985-10-22

Publication date

1986-04-23

1984-10-22 Priority claimed from US06/663,550 external-priority patent/US5441745A/en

1984-10-22 Priority claimed from US06/663,503 external-priority patent/US5435989A/en

1985-10-22 Application filed by Hope Nat Medical Center, Vestar Research Inc filed Critical Hope Nat Medical Center

1985-10-22 Publication of DK484585D0 publication Critical patent/DK484585D0/da

1986-04-23 Publication of DK484585A publication Critical patent/DK484585A/da

1993-11-22 Application granted granted Critical

1993-11-22 Publication of DK167556B1 publication Critical patent/DK167556B1/da

Links

239000002245 particle Substances 0.000 title abstract 7
206010028980 Neoplasm Diseases 0.000 title abstract 3
239000002246 antineoplastic agent Substances 0.000 title abstract 3
229940127089 cytotoxic agent Drugs 0.000 title abstract 3
239000012216 imaging agent Substances 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 3
238000003384 imaging method Methods 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
210000001539 phagocyte Anatomy 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Physics & Mathematics (AREA)
Dispersion Chemistry (AREA)
Optics & Photonics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK484585A 1984-10-22 1985-10-22 Anvendelse af en micellepartikelkomposition, hvori partiklerne i sig selv har indkapslet et kemoterapeutisk middel, til fremstilling af et intravenoest indgiveligt farmaceutisk praeparat til indfoerelse af partikelkompositionen og det kemoterapeutiske middel i tumorceller DK167556B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US66350384		1984-10-22
US66355084		1984-10-22
US06/663,550 US5441745A (en)	1982-03-30	1984-10-22	Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body
US06/663,503 US5435989A (en)	1982-03-30	1984-10-22	Method of targeting a specific location in a body

Publications (3)

Publication Number	Publication Date
DK484585D0 DK484585D0 (da)	1985-10-22
DK484585A true DK484585A (da)	1986-04-23
DK167556B1 DK167556B1 (da)	1993-11-22

Family

ID=27098764

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK482685A DK482685D0 (da)	1984-10-22	1985-10-21	Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme
DK484585A DK167556B1 (da)	1984-10-22	1985-10-22	Anvendelse af en micellepartikelkomposition, hvori partiklerne i sig selv har indkapslet et kemoterapeutisk middel, til fremstilling af et intravenoest indgiveligt farmaceutisk praeparat til indfoerelse af partikelkompositionen og det kemoterapeutiske middel i tumorceller

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK482685A DK482685D0 (da)	1984-10-22	1985-10-21	Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme

Country Status (11)

Country	Link
EP (1)	EP0179444B1 (da)
JP (1)	JPH0747533B2 (da)
KR (1)	KR900004802B1 (da)
AT (1)	ATE64298T1 (da)
CA (1)	CA1298548C (da)
DE (2)	DE3583204D1 (da)
DK (2)	DK482685D0 (da)
HK (1)	HK119993A (da)
IE (1)	IE58659B1 (da)
LU (1)	LU88811I2 (da)
NL (1)	NL960020I1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE60901B1 (en) *	1986-08-21	1994-08-24	Vestar Inc	Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics
US5043107A (en) *	1986-08-21	1991-08-27	Vestar Research, Inc.	Preparation small unilamellar vesicles including polyene antifungal antibiotics
IL88076A (en) *	1987-10-28	1993-01-14	Nippon Shinyaku Co Ltd	Fat emulsions as drug carriers
AU598958B2 (en)	1987-11-12	1990-07-05	Vestar, Inc.	Improved amphotericin b liposome preparation
US5648532A (en) *	1993-06-03	1997-07-15	The Regents Of The University Of California	Compositions for boron neutron capture therapy and methods thereof
EP0806969A2 (de) *	1995-02-09	1997-11-19	Schering Aktiengesellschaft	Kontrastmittelhaltige liposomen für die darstellung des intravasalraumes
NO312708B1 (no) *	2000-02-21	2002-06-24	Anticancer Therapeutic Inv Sa	Radioaktive liposomer til terapi
EP1684723A4 (en) *	2003-11-21	2007-06-20	Fujifilm Corp	CONTRAST MEDIUM COMPRISING LIPOSOMES CONTAINING A HYDROPHOBIC CHELATE COMPOUND
EP1745788A1 (de) *	2005-07-22	2007-01-24	KTB Tumorforschungsgesellschaft mbH	Acylglycerophospholipide zur Behandlung von Krebs und Tumorkachexie
WO2012066896A1 (ja) *	2010-11-19	2012-05-24	Kato Junji	組合わせ医薬製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4310505A (en) *	1979-11-08	1982-01-12	California Institute Of Technology	Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
JPS59122423A (ja) *	1982-12-28	1984-07-14	Green Cross Corp:The	制癌剤含有脂肪乳剤
JPS59163315A (ja) *	1983-03-09	1984-09-14	Mitsui Pharmaceut Inc	カルモフ−ル含有リポソ−ム

1985
- 1985-10-21 DK DK482685A patent/DK482685D0/da not_active Application Discontinuation
- 1985-10-21 IE IE260285A patent/IE58659B1/en not_active IP Right Cessation
- 1985-10-21 CA CA000493488A patent/CA1298548C/en not_active Expired - Lifetime
- 1985-10-22 DE DE8585113386T patent/DE3583204D1/de not_active Expired - Lifetime
- 1985-10-22 JP JP60236230A patent/JPH0747533B2/ja not_active Expired - Lifetime
- 1985-10-22 EP EP85113386A patent/EP0179444B1/en not_active Expired - Lifetime
- 1985-10-22 KR KR1019850007773A patent/KR900004802B1/ko not_active Expired
- 1985-10-22 DE DE19675031C patent/DE19675031I2/de active Active
- 1985-10-22 DK DK484585A patent/DK167556B1/da active Protection Beyond IP Right Term
- 1985-10-22 AT AT85113386T patent/ATE64298T1/de active
- 1985-10-22 LU LU88811C patent/LU88811I2/fr unknown
1993
- 1993-11-04 HK HK1199/93A patent/HK119993A/en not_active IP Right Cessation
1996
- 1996-08-09 NL NL960020C patent/NL960020I1/nl unknown

Also Published As

Publication number	Publication date
DK484585D0 (da)	1985-10-22
LU88811I2 (fr)	1996-11-05
DE19675031I2 (de)	2008-04-10
JPH0747533B2 (ja)	1995-05-24
CA1298548C (en)	1992-04-07
HK119993A (en)	1993-11-12
DK167556B1 (da)	1993-11-22
IE852602L (en)	1986-04-22
KR900004802B1 (ko)	1990-07-06
JPS61158932A (ja)	1986-07-18
DK482685D0 (da)	1985-10-21
EP0179444B1 (en)	1991-06-12
DE3583204D1 (de)	1991-07-18
IE58659B1 (en)	1993-11-03
EP0179444A3 (en)	1987-08-12
EP0179444A2 (en)	1986-04-30
ATE64298T1 (de)	1991-06-15
NL960020I1 (nl)	1996-11-01
KR860003514A (ko)	1986-05-26

Legal Events

Date	Code	Title	Description
1993-11-22	B1	Patent granted (law 1993)
1996-10-28	CTFF	Application for supplementary protection certificate (spc) filed	Free format text: CA 1996 00017, 960906
2005-11-07	PUP	Patent expired
2007-12-03	CTFF	Application for supplementary protection certificate (spc) filed	Spc suppl protection certif: CA 1996 00017 Filing date: 19960906 Expiry date: 20100524

Publication	Publication Date	Title
AU4515985A (en)	1986-01-23	New tetrapyrrole therapeutic agents
MY110186A (en)	1998-02-28	The use of tyloxapol as a nanoparticle stabilizer and dispersant.
ES8304797A1 (es)	1983-03-16	"procedimiento para la preparacion de nuevas formas orales de dipiridamol, en forma de granulados, pastillas o tabletas".
EP0430968A4 (en)	1993-10-20	Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles
ATE121082T1 (de)	1995-04-15	Tri-azamakrozyklen und deren metall komplexe.
EP0165454A3 (en)	1986-12-30	Dentifrice for hypersensitive teeth
CA2153326A1 (en)	1995-05-18	Taxane formulations comprising phospholipids
GB2128088B (en)	1986-04-30	Oral mopidamol preparations
HU9200226D0 (en)	1992-04-28	Active agent particles with modified cover
DK484585D0 (da)	1985-10-22	Micellulaere partikelkompositioner, hvori er indkapslet billedtagende og kemoterapeutiske midler for tumorer, og kompositionernes anvendelse
ES8608528A1 (es)	1986-07-16	Procedimiento para la fabricacion de fosfatidilserina para el tratamiento de desordenes del sistema nervioso central
MX9504023A (es)	1997-05-31	Composicion farmaceutica y transdermicamente activa que contiene acido 5-aminolaevulinico y procedimiento para su preparacion.
KR930700163A (ko)	1993-03-13	연조직 종양의 치료 및/또는 진단 방법
FI850613A0 (fi)	1985-02-14	Isoxazolderivat, foerfarande foer framstaellning av dessa samt dessa foereningar innehaollande laekemedel.
AU559192B2 (en)	1987-02-26	Composition for treating myocardial infarction
ATE70456T1 (de)	1992-01-15	Verwendung von micellaren partikeln zur herstellung von zusammensetzungen zum beschiessen von tumoren in menschen und deren verwendung.
EP0201005A3 (en)	1987-05-20	99mtc(iii)myocardial imaging agents which are non-reducable in vivo
Anghileri et al.	1976	57Co-hematoporphyrin accumulation by experimental tumors
DE3465014D1 (en)	1987-09-03	Podophyllotoxin preparations for use in the treatment of genital warts
IT1242026B (it)	1994-02-02	Composizione farmaceutica contenente un complesso ferro-schizokinene per il trattamento dell'anemia ferropenica.